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https://www.readbyqxmd.com/read/29219904/incivility-in-the-emergency-department-implications-for-nurse-leaders
#1
Katy Garth, Dana Todd, Dina Byers, Betty Kuiper
Uncivil behavior leads to low self-esteem, anxiety, sleep disturbance, recurrent nightmares, and depression. This article looks at the perception of incivility among emergency department nurses and the leadership required to implement evidence-based strategies to address this growing problem.
January 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29216784/evaluation-of-peripheral-serotonin-content-and-%C3%AE-2-adrenergic-receptor-function-as-potential-markers-for-life-long-recurrent-depressive-disorder-by-using-methodological-improvements
#2
Boris Aleksovski, Antoni Novotni, Viktorija Vujović, Vladimir Rendevski, Nensi Manusheva, Violeta Neceva, Ana Filipce, Aleksandar Risteski, Vasko Aleksovski, Icko Gjorgoski
OBJECTIVE: We aimed to evaluate the role and the relations between peripheral platelet serotonin content, blood plasma serotonin concentration and the function of platelet α2-adrenergic receptors (α2-AR) as potential state or trait biomarkers for recurrent depressive disorder (RDD). METHODS: 26 drug-free patients with life-long RDD and 31 healthy controls were included in the study. Several methodological improvements in blood collection and platelet isolation were implemented following the present standards in Haematology and Light transmission aggregometry...
December 7, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29215743/driven-exercise-in-the-absence-of-binge-eating-implications-for-purging-disorder
#3
Janet A Lydecker, Megan Shea, Carlos M Grilo
OBJECTIVE: Purging disorder (PD) is characterized by recurrent purging without objectively large binge-eating episodes. PD has received relatively little attention, and questions remain about the clinical significance of "purging" by exercise that is driven or compulsive (i.e., as extreme compensatory or weight-control behavior). The little available research suggests that individuals who use exercise as a compensatory behavior might have less eating-disorder psychopathology than those who purge by vomiting or laxatives, but those studies have had smaller sample sizes, defined PD using low-frequency thresholds, and defined exercise without weight-compensatory or driven elements...
December 7, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29213344/psychotherapy-for-major-depressive-disorder-and-generalized-anxiety-disorder-a-health-technology-assessment
#4
(no author information available yet)
Background: Major depressive disorder and generalized anxiety disorder are among the most commonly diagnosed mental illnesses in Canada; both are associated with a high societal and economic burden. Treatment for major depressive disorder and generalized anxiety disorder consists of pharmacological and psychological interventions. Three commonly used psychological interventions are cognitive behavioural therapy (CBT), interpersonal therapy, and supportive therapy. The objectives of this report were to assess the effectiveness and safety of these types of therapy for the treatment of adults with major depressive disorder and/or generalized anxiety disorder, to assess the cost-effectiveness of structured psychotherapy (CBT or interpersonal therapy), to calculate the budget impact of publicly funding structured psychotherapy, and to gain a greater understanding of the experiences of people with major depressive disorder and/or generalized anxiety disorder...
2017: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/29205026/prevalence-risk-factors-and-prognosis-of-depressive-disorders
#5
Niina Markkula, Jaana Suvisaari
In Finland, one out of ten adults had a depressive disorder on 2011, and compared to year 2000, the prevalence increased especially in women. Risk factors for recurrent depressive episodes included female gender, young age, childhood adversities, and prior mild depressive symptoms. During follow-up, 75% of patients recovered, and the risk for prolonged depression was increased in those living alone or with severe symptoms. Depressive disorders are associated with a two-fold risk of death, which can only partly be explained by physical illness and negative health behavior...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29204093/evaluation-of-the-adenosine-deaminase-ada-g22a-gene-polymorphism-with-recurrent-spontaneous-abortion-among-egyptian-patients
#6
Hanan Mohamed Farhan, Khadiga Abu-Gabal, Maha Katta, Raghda Ibrahim
Introduction: Adenosine and deoxyadenosine metabolism is influenced by adenosine deaminase (ADA) enzyme. ADA increases in different diseases and is considered as one of the markers for cell-mediated immunity. Pregnancy is associated with depressed cell-mediated immunity. The level of ADA expression, which seems to play a key role in maintaining pregnancy, is influenced by adenosine deaminase G22A gene polymorphism. We aimed in our study to evaluate the association of ADA G22A gene polymorphism with recurrent spontaneous abortion (RSA) in Egyptian women...
2017: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/29203867/sensory-stream-adaptation-in-chaotic-networks
#7
Adam Ponzi
Implicit expectations induced by predictable stimuli sequences affect neuronal response to upcoming stimuli at both single cell and neural population levels. Temporally regular sensory streams also phase entrain ongoing low frequency brain oscillations but how and why this happens is unknown. Here we investigate how random recurrent neural networks without plasticity respond to stimuli streams containing oddballs. We found the neuronal correlates of sensory stream adaptation emerge if networks generate chaotic oscillations which can be phase entrained by stimulus streams...
December 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29200575/are-we-overdiagnosing-bipolar-disorder
#8
M S Reddy, Starlin M Vijay, Swetha Reddy
Bipolar disorder (BD) is an established diagnostic entity used by clinicians for over a century. It is distinguished by the distinct manic and depressive episodes with interepisode euthymia. It has an illness course where both recovery and recurrences are a rule and has a good long-term prognosis, as reported earlier by Emil Kraeplin. There is an opinion in the current literature that BD is often underdiagnosed as unipolar depression, and based on that opinion, spectrum concept was introduced. Here, we present 5 cases to highlight that overdiagnosis of BD is also not infrequent and we discuss its reasons and therapeutic implications...
September 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29199760/effectivity-and-cost-effectivity-of-the-maintenance-electroconvulsive-therapy-a-mirror-naturalistic-analysis
#9
Albert Cosculluela, Jesús Cobo, Erika Martínez-Amorós, Montse Paños, Angel M Santiago, Sara Crivillés, María Camposo, Joan C Oliva, Albert Granero, Diego J Palao
INTRODUCTION: Maintenance Electroconvulsive Therapy (mECT) is a biological long-term treatment in which patients receive ECT on periods from 2 to 4 weeks, during a variable period of time, usually for more than 6 months. Recent studies showed the efficacy of mECT in prevention of relapse and recurrences. Our study wants to demostrate the effectivity and cost-effectivity of this therapy in the naturalistic conditions of our area. METHODOLOGY: HASH(0x4f29288) DESIGN: Retrospective longitudinal study, with mirror analysis in naturalistic conditions...
November 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29197414/integrated-mental-health-care-and-vocational-rehabilitation-to-improve-return-to-work-rates-for-people-on-sick-leave-because-of-depression-and-anxiety-the-danish-ibbis-trial-study-protocol-for-a-randomized-controlled-trial
#10
Rie Poulsen, Andreas Hoff, Jonas Fisker, Carsten Hjorthøj, Lene Falgaard Eplov
BACKGROUND: Depression and anxiety are among the largest contributors to the global burden of disease and have negative effects on both the individual and society. Depression and anxiety are very likely to influence the individual's work ability, and up to 40% of the people on sick leave in Denmark have depression and/or anxiety. There is no clear evidence that treatment alone will provide sufficient support for vocational recovery in this group. Integrated vocational and health care services have shown good effects on return to work in other, similar welfare contexts...
December 2, 2017: Trials
https://www.readbyqxmd.com/read/29197404/integrated-mental-health-care-and-vocational-rehabilitation-to-improve-return-to-work-rates-for-people-on-sick-leave-because-of-exhaustion-disorder-adjustment-disorder-and-distress-the-danish-ibbis-trial-study-protocol-for-a-randomized-controlled-trial
#11
Rie Poulsen, Jonas Fisker, Andreas Hoff, Carsten Hjorthøj, Lene Falgaard Eplov
BACKGROUND: Common mental disorders are important contributors to the global burden of disease and cause negative effects on both the individual and society. Stress-related disorders influence the individual's workability and cause early retirement pensions in Denmark. There is no clear evidence that mental health care alone will provide sufficient support for vocational recovery for this group. Integrated vocational and health care services have shown good effects on return to work in other similar welfare contexts...
December 2, 2017: Trials
https://www.readbyqxmd.com/read/29197212/recurrent-transitory-ischemic-attacks-with-subsequent-development-of-the-ischemic-stroke-as-initial-manifestation-of-eosinophilic-granulomatosis-with-polyangiitis-in-depressed-patient
#12
Darija Mahovic, Nenad Lakusic, Ivana Ljubicic, Nadica Laktasic Zerjavic, Katarina Ivana Tudor, Gordan Pavlisa
No abstract text is available yet for this article.
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29196145/effects-of-imipramine-on-cytokines-panel-in-the-rats-serum-during-the-drug-treatment-and-discontinuation
#13
M Kuśmider, A Faron-Górecka, P Pabian, J Solich, M Szlachta, M Kolasa, D Żurawek, J Wójcikowski, W Daniel, M Dziedzicka-Wasylewska
Time dependent sensitization (TDS) - phenomenon described originally by Chiodo and Antelman (1980) in context of dopamine receptors, refers to cascade of events that continue to develop in the organism, after the initiating stimulus is no longer available. Treatment could be recognized as such a initiating stimulus (in case of depression, example of electroconvulsive therapy would be obvious, but some aspects of pharmacotherapy too). The process leads to improvement, but, on the other hand, phenomena of kindling in recurrent depression is well known (more relapses and therapies make heavier and longer lasting subsequent episodes)...
November 28, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/29189031/-memory-support-strategies-and-bundles-a-pathway-to-improving-cognitive-therapy-for-depression-correction-to-dong-lee-and-harvey-2017
#14
(no author information available yet)
Reports an error in "Memory support strategies and bundles: A pathway to improving cognitive therapy for depression" by Lu Dong, Jason Y. Lee and Allison G. Harvey (Journal of Consulting and Clinical Psychology, 2017[Mar], Vol 85[3], 187-199). In the article, there was an error in Table 2 of the Results. In Table 2, the MS summary scores of the Total amount of MS are missing six descriptive statistics. They should have read as: 13.50, 8.54, 23, 18.32, 8.83, 23. The corrected table is included. (The following abstract of the original article appeared in record 2017-07144-001...
December 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29187221/autophagy-maintains-the-stemness-of-ovarian-cancer-stem-cells-by-foxa2
#15
Qiaohua Peng, Jiale Qin, Yanan Zhang, Xiaodong Cheng, Xinyu Wang, Weiguo Lu, Xing Xie, Songfa Zhang
BACKGROUND: Cancer stem cells (CSCs) are regarded as the main cell type responsible for the initiation, metastasis, drug resistance, and recurrence of cancer. But the mechanism by which cancer stem cells maintain their stemness remains unclear. METHODS AND RESULTS: In the present study, ovarian cancer stem cells (OCSCs) were revealed to have an enhanced autophagic flux. Furthermore, their chemoresistance and ability to self-renewal in vitro were decreased when autophagy was inhibited by Bafilomycin A1(BafA1), Chloroquine(CQ) or autophagy related 5(ATG5) knockdown...
November 29, 2017: Journal of Experimental & Clinical Cancer Research: CR
https://www.readbyqxmd.com/read/29184455/using-proms-to-guide-patients-and-practitioners-through-the-head-and-neck-cancer-journey
#16
REVIEW
Simon N Rogers, Brittany Barber
The measurement of patient-reported outcome measures (PROMs) following head and neck cancer (HNC) has the capacity to substantially enhance the care of patients and their care-givers following the diagnosis and treatment of HNC. Literature concerning PROMs has increased exponentially in the past 2 decades, producing a vast array of data upon which the multidisciplinary team can reflect. For this review, "Handle On QOL" has been used as a source of references to illustrate the points raised. PROMs are contextualized by considering the clinically-distinct key stages that cancer patients endure: diagnosis, treatment, acute toxicity, early recovery, late effects, recurrence, and palliation...
2017: Patient related Outcome Measures
https://www.readbyqxmd.com/read/29182613/assessment-of-type-1-and-type-3-deiodinase-expression-levels-in-depressive-disorders
#17
Elżbieta Gałecka, Anna Kumor-Kisielewska, Agata Orzechowska, Michael Maes, Paweł Górski, Janusz Szemraj
A depressive disorder is a disease characterized by a heterogenous background. The important processes observed and diagnosed in depressed patients indicate that the etiology of depression may include disturbances in thyroid hormone (TH) levels and the occurrence of immune-inflammatory activation. Type 1 (DIO1) and type 3 (DIO3) iodothyronine deiodinases are the enzymes which determine the peripheral and tissue levels of TH, but also interfere with immunological cells and inflammatory processes. We aimed to investigate the levels of DIO1 and DIO3 in the patients suffering from recurrent depressive disorders (rDD)...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29181274/assessment-of-brain-functional-connectome-alternations-and-correlation-with-depression-and-anxiety-in-major-depressive-disorders
#18
Vincent Chin-Hung Chen, Chao-Yu Shen, Sophie Hsin-Yi Liang, Zhen-Hui Li, Ming-Hong Hsieh, Yeu-Sheng Tyan, Mong-Liang Lu, Yena Lee, Roger S McIntyre, Jun-Cheng Weng
Major depressive disorder (MDD) is highly prevalent, recurrent, and associated with functional impairment, morbidity, and mortality. Herein, we aimed to identify disruptions in functional connectomics among subjects with MDD by using resting-state functional magnetic resonance imaging (rs-fMRI). Sixteen subjects with MDD and thirty health controls completed resting-state fMRI scans and clinical assessments (e.g., Hamilton Depression Rating Scale (HAMD) and Hospital Anxiety and Depression Scale (HADS)). We found higher amplitude of low frequency fluctuations (ALFF) bilaterally in the hippocampus and amygdala among MDD subjects when compared to healthy controls...
2017: PeerJ
https://www.readbyqxmd.com/read/29179144/the-centrality-of-dsm-and-non-dsm-depressive-symptoms-in-han-chinese-women-with-major-depression
#19
Kenneth S Kendler, Steven H Aggen, Jonathan Flint, Denny Borsboom, Eiko I Fried
INTRODUCTION: We compared DSM-IV criteria for major depression (MD) with clinically selected non-DSM criteria in their ability to represent clinical features of depression. METHOD: We conducted network analyses of 19 DSM and non-DSM symptoms of MD assessed at personal interview in 5952 Han Chinese women meeting DSM-IV criteria for recurrent MD. We estimated an Ising model (the state-of-the-art network model for binary data), compared the centrality (interconnectedness) of DSM-IV and non-DSM symptoms, and investigated the community structure (symptoms strongly clustered together)...
November 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29174739/episode-accumulation-associated-with-hastened-recurrence-and-delayed-recovery-in-bipolar-disorder
#20
Dong Yeon Park, Dennis Do, Lauren Chang, Saloni Shah, Laura D Yuen, Farnaz Hooshmand, Po W Wang, Shefali Miller, Terence A Ketter
AIMS: Assess episode accumulation (≥ 10 prior mood episodes) associations with demographic/baseline clinical characteristics and mood episode recurrence/recovery in bipolar disorder (BD). METHODS: Stanford BD Clinic outpatients enrolled during 2000-2011 were assessed with Systematic Treatment Enhancement Program for BD (STEP-BD) Affective Disorders Evaluation. Among recovered and syndromal mood episode patients, we assessed episode accumulation associations with demographic/baseline clinical characteristics and with recurrence/recovery (by Kaplan-Meier survival analyses, with mediators assessed with Cox Proportional Hazard Ratio (HR) analyses)...
November 15, 2017: Journal of Affective Disorders
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