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https://www.readbyqxmd.com/read/28426918/advanced-cancer-caregiving-as-a-risk-for-major-depressive-episodes-and-generalized-anxiety-disorder
#1
Kelly M Trevino, Holly G Prigerson, Paul K Maciejewski
OBJECTIVE: Caregivers of advanced cancer patients provide extensive care associated with high levels of caregiver distress. The degree to which cancer caregiving increases caregivers' risk for a psychiatric disorder is unknown. The current study examines whether advanced cancer caregiving poses distinct risks for initial and recurrent major depressive episodes (MDEs) and generalized anxiety disorder (GAD) relative to the general population. METHODS: Caregivers of advanced cancer patients (N = 540) from Coping with Cancer were compared to general population controls (N = 9,282) from the National Comorbidity Survey Replication...
April 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28424925/cross-vertical-mattress-suturing-with-basilar-tightening-during-the-correction-of-inverted-nipple-in-30-cases
#2
Weizhong Liang, Zuojun Zhao, Shu Liu, Tingmin Gu
OBJECTIVE: To investigate the efficacy of cross vertical mattress suturing with basilar tightening during the correction of inverted nipple. METHODS: Thirty patients with inverted nipples underwent cross vertical mattress suturing with basilar tightening. The postoperative results were recorded. RESULTS: All the patients were followed up for 6 months to 2 years. The results of 28 cases were satisfactory, and there was no recurrence. Two patients relapsed, and a mild depression was formed...
April 19, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28420655/syncope-and-its-impact-on-occupational-accidents-and-employment-a-danish-nationwide-retrospective-cohort-study
#3
Anna-Karin Numé, Kristian Kragholm, Nicolas Carlson, Søren L Kristensen, Henrik Bøggild, Mark A Hlatky, Christian Torp-Pedersen, Gunnar Gislason, Martin H Ruwald
BACKGROUND: First-time syncopal episodes usually occur in adults of working age, but their impact on occupational safety and employment remains unknown. We examined the associations of syncope with occupational accidents and termination of employment. METHODS AND RESULTS: Through linkage of Danish population-based registers, we included all residents 18 to 64 years from 2008 to 2012. Among 3 410 148 eligible individuals, 21 729 with a first-time diagnosis of syncope were identified, with a median age 48...
April 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28418198/stress-is-associated-with-an-increased-risk-of-recurrent-seizures-in-adults
#4
Elisa Baldin, W Allen Hauser, Alison Pack, Dale C Hesdorffer
OBJECTIVE: The literature is sparse on the complex interrelationships between stressors, depression, anxiety disorders, and epilepsy. We hypothesized that a relationship exists between stress and epilepsy. We evaluated whether markers of stress are associated with seizure recurrence in a low income community-based cohort of adults with single unprovoked seizure or newly diagnosed epilepsy. METHODS: We ascertained adult residents of Northern Manhattan and Harlem, New York City, with a first unprovoked seizure or newly diagnosed epilepsy, between December 2010 and January 2013...
April 18, 2017: Epilepsia
https://www.readbyqxmd.com/read/28414131/cyclical-corticosterone-administration-sensitizes-depression-like-behavior-in-rats
#5
Katherina A Lebedeva, Hector J Caruncho, Lisa E Kalynchuk
Because stress is a significant risk factor for depression, many animal models of depression employ chronic stress as a precipitating event. However, almost without exception, stress-induced animal models of depression focus on a single bout of depression and therefore, they do not provide any means to understand the typical cycling of mood observed in most patients with depression. Here we assessed whether repeated cycles of exposure to the stress hormone corticosterone would sensitize depression-like behavior...
April 13, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28412613/intensified-emotion-perception-in-depression-differences-in-physiological-arousal-and-subjective-perceptions
#6
Sofia Wenzler, Marleen Hagen, Mika P Tarvainen, Marietheres Hilke, Naddy Ghirmai, Ann-Caitlin Huthmacher, Marco Trettin, Rolf van Dick, Andreas Reif, Viola Oertel-Knöchel
People suffering from depression perceive themselves and their surroundings as more negative than healthy ones. An explanation might be that depressed individuals experience negative information as more stressful than non-depressed subjects and, consequently, respond in an amplified manner on a subjective and physiological level. To test this proposition, we presented 41 patients with recurrent depressive episodes and 42 controls with stimuli from the International Affective Picture System split into three valence categories while different parameters of physiological arousal (e...
April 2, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28407526/the-impact-of-antidepressants-on-seizure-frequency-and-depressive-and-anxiety-disorders-of-patients-with-epilepsy-is-it-worth-investigating
#7
Ramses Ribot, Bichun Ouyang, Andres M Kanner
PURPOSE: Depression and anxiety disorders in patients with epilepsy (PWE) remain under-recognized and under-treated, despite being the most common psychiatric co-morbidities. Selective serotonin re-uptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are considered first-line treatment for primary depression and anxiety disorders. We performed this study to investigate if SSRIs and SNRIs could affect the seizure frequency of PWE and to assess whether such effect is independent of the response of the mood and anxiety disorders to these drugs...
April 10, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28406681/affective-enhancement-of-working-memory-is-maintained-in-depression
#8
Susanne Schweizer, Lauren Navrady, Lauren Breakwell, Rachel M Howard, Ann-Marie Golden, Aliza Werner-Seidler, Tim Dalgleish
We currently know little about how performance on assessments of working memory capacity (WMC) that are designed to mirror the concurrent task demands of daily life are impacted by the presence of affective information, nor how those effects may be modulated by depression-a syndrome where sufferers report global difficulties with executive processing. Across 3 experiments, we investigated WMC for sets of neutral words in the context of processing either neutral or affective (depressogenic) sentences, which had to be judged on semantic accuracy (Experiments 1 and 2) or self-reference (Experiment 3)...
April 13, 2017: Emotion
https://www.readbyqxmd.com/read/28406052/the-psychometric-properties-of-the-perceived-stress-scale-10-among-patients-with-systemic-lupus-erythematosus
#9
S D Mills, D Azizoddin, G Z Racaza, D J Wallace, M H Weisman, P M Nicassio
Objective Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease characterized by periods of remission and recurrent flares, which have been associated with stress. Despite the significance of stress in this disease, the Perceived Stress Scale-10 has yet to be psychometrically evaluated in patients with SLE. Methods Exploratory factor analysis was used to examine the structural validity of the Perceived Stress Scale-10 among patients with SLE ( N = 138) receiving medical care at Cedars Sinai Medical Center...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28400711/cannabinoid-hyperemesis-and-the-cyclic-vomiting-syndrome-in-adults-recognition-diagnosis-acute-and-long-term-treatment
#10
REVIEW
Christian G Blumentrath, Boris Dohrmann, Nils Ewald
The cannabinoid hyperemesis syndrome (CHS) and the cyclic vomiting syndrome in adults (CVS) are both characterized by recurrent episodes of heavy nausea, vomiting and frequently abdominal pain. Both syndromes are barely known among physicians. Literature is inconsistent concerning clinical features which enable differentiation between CVS and CHS. We performed a literature review using the LIVIVO search portal for life sciences to develop a pragmatic approach towards these two syndromes. Our findings indicate that complete and persistent resolution of all symptoms of the disease following cannabis cessation is the only reliable criterion applicable to distinguish CHS from CVS...
2017: German Medical Science: GMS E-journal
https://www.readbyqxmd.com/read/28399092/-the-affective-pathology-in-patients-with-adolescent-bulimia-nervosa
#11
V V Grachev
AIM: To investigate affective pathology in patients with adolescent bulimia nervosa (BN) and to analyze comorbid mutual influences of these clinical entities. MATERIAL AND METHODS: A sample consisted of 52 young female patients, aged from 13.9 to 17.4 years, who simultaneously meet ICD-10 criteria of F50.2 - typical BN and F30-F39 - mood disorders. The Eating Attitudes Test (EAT-26) and the Beck Depression Inventory were used for psychometric assessment. Duration of follow-up ranged from 1 to 7 years...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28393267/charting-the-perfect-storm-emerging-biological-interfaces-between-stress-and-stroke
#12
REVIEW
G Kronenberg, J Schöner, C Nolte, A Heinz, M Endres, Karen Gertz
A growing body of evidence demonstrates that psychosocial stress is an important and often underestimated risk factor for cardiovascular disease such as myocardial infarction and stroke. In this article, we map out major biological interfaces between stress, stress-related psychiatric disorders, and stroke, placing special emphasis on the fact that stress and psychiatric disorders may be both cause and consequence of cardiovascular disease. Apart from high-risk lifestyle habits such as smoking and lack of exercise, neuroendocrine dysregulation, alterations of the hemostatic system, increased oxidative stress, and inflammatory changes have been implicated in stress-related endothelial dysfunction...
April 9, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28391385/the-association-between-a-lifetime-history-of-low-back-injury-in-a-motor-vehicle-collision-and-future-low-back-pain-a-population-based-cohort-study
#13
Paul S Nolet, Vicki L Kristman, Pierre Côté, Linda J Carroll, J David Cassidy
PURPOSE: This population-based cohort study investigated the association between a lifetime history of a low back injury in a motor vehicle collision (MVC) and future troublesome low back pain. Participants with a history of a low back injury in a motor vehicle collision who had recovered (no or mild low back pain) were compared to those without a history of injury. Current evidence from two cross-sectional and one prospective study suggests that individuals with a history of a low back injury in a MVC are more likely to experience future LBP...
April 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28390496/kindling-of-life-stress-in-bipolar-disorder-effects-of-early-adversity
#14
Benjamin G Shapero, Rachel B Weiss, Taylor A Burke, Elaine M Boland, Lyn Y Abramson, Lauren B Alloy
Most theoretical frameworks regarding the role of life stress in bipolar disorders (BD) do not incorporate the possibility of a changing relationship between psychosocial context and episode initiation across the course of the disorder. The kindling hypothesis theorizes that over the longitudinal course of recurrent affective disorders, the relationship between major life stressors and episode initiation declines (Post, 1992). The present study aimed to test an extension of the kindling hypothesis in BD by examining the effect of early life adversity on the relationship between proximal life events and prospectively assessed mood episodes...
May 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28388454/initial-steps-to-inform-selection-of-continuation-cognitive-therapy-or-fluoxetine-for-higher-risk-responders-to-cognitive-therapy-for-recurrent-major-depressive-disorder
#15
Jeffrey R Vittengl, Lee Anna Clark, Michael E Thase, Robin B Jarrett
Responders to acute-phase cognitive therapy (A-CT) for major depressive disorder (MDD) often relapse or recur, but continuation-phase cognitive therapy (C-CT) or fluoxetine reduces risks for some patients. We tested composite moderators of C-CT versus fluoxetine's preventive effects to inform continuation treatment selection. Responders to A-CT for MDD judged to be at higher risk for relapse due to unstable or partial remission (N=172) were randomized to 8 months of C-CT or fluoxetine with clinical management and assessed, free from protocol treatment, for 24 additional months...
March 22, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28386925/vagus-nerve-stimulation-surgical-technique-of-implantation-and-revision-and-related-morbidity
#16
Flavio Giordano, Anna Zicca, Carmen Barba, Renzo Guerrini, Lorenzo Genitori
Indications for vagus nerve stimulation (VNS) therapy include focal, multifocal epilepsy, drop attacks (tonic/atonic seizures), Lennox-Gastaut syndrome, tuberous sclerosis complex (TSC)-related multifocal epilepsy, and unsuccessful resective surgery. Surgical outcome is about 50-60% for seizures control, and may also improve mood, cognition, and memory. On this basis, VNS has also been proposed for the treatment of major depression and Alzheimer's' disease. The vagus nerve stimulator must be implanted with blunt technique on the left side to avoid cardiac side effects through the classic approach for anterior cervical discectomy...
April 2017: Epilepsia
https://www.readbyqxmd.com/read/28385483/analgesic-use-and-risk-of-recurrent-falls-in-participants-with-or-at-risk-of-knee-osteoarthritis-data-from-the-osteoarthritis-initiative
#17
W-H Lo-Ciganic, L Floden, J K Lee, E L Ashbeck, L Zhou, C Chinthammit, A W Purdy, C K Kwoh
OBJECTIVE: Few studies have compared the risk of recurrent falls across different types of analgesic use, and were limited to adjust for potential confounders (e.g., pain/depression severity). We aimed to assess analgesic use and the subsequent risk of recurrent falls, among participants with or at risk of knee osteoarthritis (OA). METHODS: A longitudinal analysis included 4231 participants aged 45-79 years at baseline with 4-year follow-up from the Osteoarthritis Initiative (OAI) cohort study...
April 4, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28377699/computational-model-of-recurrent-subthalamo-pallidal-circuit-for-generation-of-parkinsonian-oscillations
#18
Osamu Shouno, Yoshihisa Tachibana, Atsushi Nambu, Kenji Doya
Parkinson's disease is a movement disorder caused by dopamine depletion in the basal ganglia. Abnormally synchronized neuronal oscillations between 8 and 15 Hz in the basal ganglia are implicated in motor symptoms of Parkinson's disease. However, how these abnormal oscillations are generated and maintained in the dopamine-depleted state is unknown. Based on neural recordings in a primate model of Parkinson's disease and other experimental and computational evidence, we hypothesized that the recurrent circuit between the subthalamic nucleus (STN) and the external segment of the globus pallidus (GPe) generates and maintains parkinsonian oscillations, and that the cortical excitatory input to the STN amplifies them...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28377244/trigeminal-neuralgia-toward-a-multimodal-approach
#19
REVIEW
Alfio Spina, Pietro Mortini, Federica Alemanno, Elise Houdayer, Sandro Iannaccone
OBJECTIVES: Trigeminal neuralgia (TN) is the most common cranial neuralgia in adults, with a slight prevalence in women. Antiepileptic drugs represent the mainstay of the medical treatment, whereas microvascular decompression is the best option in case of neurovascular conflict. Although these treatments showed good rate of efficacy, they can be contraindicated in some patients and more than 50% of patients undergoing these treatments will present recurrence of pain in the following months...
April 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28369185/lower-likelihood-of-falling-at-age-90-is-associated-with-daily-exercise-a-quarter-of-a-century-earlier-the-90-study
#20
Annlia Paganini-Hill, Dana E Greenia, Shawna Perry, Seyed Ahmad Sajjadi, Claudia H Kawas, Maria M Corrada
Objective: to explore the relationship between risk of falling at age 90+ and prior physical activity at age 60-70s. Design: population-based cohort study (The 90+ Study). Setting: California retirement community. Participants: of 1596 cohort members, 1536 had both falls and prior activity data. Mean age = 94 years; 78% female; 99% Caucasian. Methods: time spent in active physical activity was self-reported in 1980s; medical history, medication, assistive devices, residence type, and falls (outcome) was collected in 2000s...
March 21, 2017: Age and Ageing
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