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Relaxometry

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https://www.readbyqxmd.com/read/28928507/characteristics-of-xanthosoma-sagittifolium-roots-during-cooking-using-physicochemical-analysis-uniaxial-compression-multispectral-imaging-and-low-field-nmr-spectroscopy
#1
Abena Achiaa Boakye, María Gudjónsdóttir, Jacob Lercke Skytte, Ioannis S Chronakis, Faustina Dufie Wireko-Manu, Ibok Oduro
To effectively promote the industrial utilization of cocoyam (Xanthosoma sagittifolium) roots for enhanced food sustainability and security, there is a need to study their molecular, mechanical and physicochemical properties in detail. The physicochemical and textural characteristics of the red and white varieties of cocoyam roots were thus analysed by low field nuclear magnetic resonance relaxometry, multispectral imaging, uniaxial compression testing, and relevant physicochemical analysis in the current study...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28923493/diagnosis-and-quantification-of-the-iron-overload-through-magnetic-resonance
#2
J M Alústiza Echeverría, M C Barrera Portillo, A Guisasola Iñiguiz, A Ugarte Muño
There are different magnetic resonance techniques and models to quantify liver iron concentration. T2 relaxometry methods evaluate the iron concentration in the myocardium, and they are able to discriminate all the levels of iron overload in the liver. Signal intensity ratio methods saturate with high levels of liver overload and can not assess iron concentration in the myocardium but they are more accessible and are very standardized. This article reviews, in different clinical scenarios, when Magnetic Resonance must be used to assess iron overload in the liver and myocardium and analyzes the current challenges to optimize the aplication of the technique and to be it included in the clinical guidelines...
September 15, 2017: Radiología
https://www.readbyqxmd.com/read/28921712/a-review-of-nmr-methods-used-in-the-study-of-the-structure-and-dynamics-of-ionic-liquids
#3
Raju Nanda, Krishnan Damodaran
Recently, NMR spectroscopy has been emerging out as a powerful tool to study the structure and dynamics of ionic liquids (ILs) and ILs-Li(+) salt mixtures. This mini-review primarily focuses on the applications of various NMR spectroscopic techniques such as self-diffusion measurements, NMR relaxometry, two-dimensional NMR and other novel NMR approaches to study the structure and dynamics of ILs and its mixtures with lithium salts.
September 18, 2017: Magnetic Resonance in Chemistry: MRC
https://www.readbyqxmd.com/read/28912434/food-grade-filler-particles-as-an-alternative-method-to-modify-the-texture-and-stability-of-myofibrillar-gels
#4
Andrew J Gravelle, Shai Barbut, Alejandro G Marangoni
A series of food grade particles were characterized for their potential as fillers in myofibrillar gels. The fillers were separated into (i) hydrophilic, insoluble, crystalline particles and (ii) starch granules. The particles used were microcrystalline cellulose, oat fiber and walnut shell flour, as well as potato and tapioca starches. Crystalline particles increased hardness and decreased recovery properties. Although all of these fillers decreased the T2 relaxation time of water, this was dependent on particle type and size...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28911905/gaussian-process-classification-of-superparamagnetic-relaxometry-data-phantom-study
#5
Javad Sovizi, Kelsey B Mathieu, Sara L Thrower, Wolfgang Stefan, John D Hazle, David Fuentes
MOTIVATION: Superparamagnetic relaxometry (SPMR) is an emerging technology that holds potential for use in early cancer detection. Measurement of the magnetic field after the excitation of cancer-bound superparamagnetic iron oxide nanoparticles (SPIONs) enables the reconstruction of SPIONs spatial distribution and hence tumor detection. However, image reconstruction often requires solving an ill-posed inverse problem that is computationally challenging and sensitive to measurement uncertainty...
July 24, 2017: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/28881830/value-of-quantitative-magnetic-resonance-imaging-t1-relaxometry-in-predicting-contrast-enhancement-in-glioblastoma-patients
#6
Elke Hattingen, Andreas Müller, Alina Jurcoane, Burkhard Mädler, Philip Ditter, Hans Schild, Ulrich Herrlinger, Martin Glas, Sied Kebir
SUMMARIZING THE IMPORTANCE OF THE STUDY: The repetitive usage of gadolinium-based contrast agents (GBCA) is critical for magnetic resonance imaging (MRI) evaluation of tumor burden in glioblastoma patients. It is also a crucial tool for determination of radiographical response to treatment. GBCA injection, however, comes with a 2.4% rate of adverse events including life-threatening conditions such as nephrogenic systemic fibrosis (NSF). Moreover, GBCA have been shown to be deposited in brain tissue of patients even with an intact blood-brain barrier (BBB)...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28869162/a-novel-method-for-t2-quantification-in-presence-of-b1-inhomogeneities
#7
David Milford, Martin Bendszus, Sabine Heiland
INTRODUCTION: T2 relaxometry as a quantitative MRI technique offers a more precise characterization of tissue, compared with qualitative T2 weighted imaging. The issue, however, is that in typically used T2 relaxometry sequences such as a multi-spin echo sequences, incorrect refocussing flip angles and B1 inhomogeneities cause inaccuracies in T2 determination. The work presented here within presents a new technique for modelling T2 decay curves and thereby correcting T2 times altered by inhomogeneities...
August 28, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28844220/self-diffusion-studies-by-intra-and-inter-molecular-spin-lattice-relaxometry-using-field-cycling-liquids-plastic-crystals-porous-media-and-polymer-segments
#8
REVIEW
Rainer Kimmich, Nail Fatkullin
Field-cycling NMR relaxometry is a well-established technique for probing molecular dynamics in a frequency range from typically a few kHz up to several tens of MHz. For the interpretation of relaxometry data, it is quite often assumed that the spin-lattice relaxation process is of an intra-molecular nature so that rotational fluctuations dominate. However, dipolar interactions as the main type of couplings between protons and other dipolar species without quadrupole moments can imply appreciable inter-molecular contributions...
August 2017: Progress in Nuclear Magnetic Resonance Spectroscopy
https://www.readbyqxmd.com/read/28843639/characteristics-of-the-most-recently-awarded-magnetic-resonance-imaging-patents-in-the-united-states
#9
REVIEW
Sushma Gaddam, Gregory Lemberskiy, Andrew B Rosenkrantz
PURPOSE: To characterize recent magnetic resonance imaging (MRI) technical development and innovation based on data regarding MRI-related patents awarded in 2016. METHODS: The US Patent and Trademark Office website was searched for patents awarded in 2016 and an abstract containing "magnetic resonance." Patent characteristics were summarized. An MRI physicist classified patents' themes. RESULTS: A total of 423 MRI-related patents were awarded in 2016...
July 29, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28808201/thalamic-paramagnetic-iron-by-t2-relaxometry-correlates-with-severity-of-multiple-sclerosis
#10
Eva Baranovicova, Ema Kantorova, Dagmar Kalenska, Lucia Lichardusova, Michal Bittsan-Sky, Dusan Dobrota
Iron can contribute to the pathogenesis and progression of multiple sclerosis (MS) due to its accumulation in the human brain. We focus on the thalamus as an information transmitter between various subcortical and cortical areas. Thalamic iron seems to follow different rules than iron in other deep gray matter structures and its relation to the clinical outcomes of MS is still indistinct. In our study, we investigated a connection between thalamic iron and patients' disability and course of the disease. The presence of paramagnetic substances in the tissues was tracked by T2* quantification...
July 13, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28790121/cardiovascular-magnetic-resonance-relaxometry-predicts-regional-functional-outcome-after-experimental-myocardial-infarction
#11
COMPARATIVE STUDY
Sebastian M Haberkorn, Christoph Jacoby, Zhaoping Ding, Petra Keul, Florian Bönner, Amin Polzin, Bodo Levkau, Jürgen Schrader, Malte Kelm, Ulrich Flögel
BACKGROUND: Cardiovascular magnetic resonance with gadolinium-based contrast agents has established as gold standard for tissue characterization after myocardial infarction (MI). Beyond accurate diagnosis, the value of cardiovascular magnetic resonance to predict the outcome after MI has yet to be substantiated. METHODS AND RESULTS: Recent cardiovascular magnetic resonance approaches were systematically compared for quantification of tissue injury and functional impairment after MI using murine models with permanent left anterior descending coronary artery ligation (n=14) or 50 minutes ischemia/reperfusion (n=13)...
August 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28775058/analysis-of-white-matter-damage-in-patients-with-multiple-sclerosis-via-a-novel-in-vivo-mr-method-for-measuring-myelin-axons-and-g-ratio
#12
A Hagiwara, M Hori, K Yokoyama, M Nakazawa, R Ueda, M Horita, C Andica, O Abe, S Aoki
BACKGROUND AND PURPOSE: Myelin and axon volume fractions can now be estimated via MR imaging in vivo, as can the g-ratio, which equals the ratio of the inner to the outer diameter of a nerve fiber. The purpose of this study was to evaluate WM damage in patients with MS via this novel MR imaging technique. MATERIALS AND METHODS: Twenty patients with relapsing-remitting MS with a combined total of 149 chronic plaques were analyzed. Myelin volume fraction was calculated based on simultaneous tissue relaxometry...
August 3, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28764065/the-use-of-two-dimensional-nmr-relaxometry-in-bread-staling-a-valuable-tool
#13
E Curti, E Carini, M F Cobo, T Bocher, E Vittadini
Staling of bread was investigated in terms of physico-chemical parameters and one (1D) and two dimensional (2D) (1)H Nuclear Magnetic Resonance (NMR) relaxometry. Physico-chemical properties were consistent with those generally reported for bread staling (crumb moisture loss, decrease in frozen water content, formation of amylopectin crystals, crumb hardening). One dimensional (1)H NMR investigation suggested the presence of only one T1 protons population, while T2 was representative of multiple proton populations, that well related to the observed physico-chemical changes...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28762536/a-novel-mr-based-method-for-detection-of-cartilage-delamination-in-femoroacetabular-impingement-patients
#14
Michael A Samaan, Valentina Pedoia, Alan L Zhang, Matthew C Gallo, Thomas M Link, Richard B Souza, Sharmila Majumdar
In this study, quantitative magnetic resonance based measurements were used to evaluate T1ρ and T2 mapping and heterogeneity in femoroacetabular impingement (FAI) patients with acetabular cartilage delamination and to determine the ability of these quantitative MR-based measurements in detecting delamination. Unilateral hip joint MR-scans of 36 FAI patients with arthroscopically-confirmed acetabular cartilage delamination and 36 age, gender, and BMI matched controls were obtained. T1ρ and T2 mapping and heterogeneity of the hip joint articular cartilage were assessed in both groups using voxel-based relaxometry (VBR)...
August 1, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28759741/correction-of-environmental-magnetic-fields-for-the-acquisition-of-nuclear-magnetic-relaxation-dispersion-profiles-below-earth-s-field
#15
Vasileios Zampetoulas, David J Lurie, Lionel M Broche
T1 relaxation times can be measured at a range of magnetic field strengths by Fast Field-Cycling (FFC) NMR relaxometry to provide T1-dispersion curves. These are valuable tools for the investigation of material properties as they provide information about molecular dynamics non-invasively. However, accessing information at fields below 230 μT (10kHz proton Larmor frequency) requires careful correction of unwanted environmental magnetic fields. In this work a novel method is proposed that compensates for the environmental fields on a FFC-NMR relaxometer and extends the acquisition of Nuclear Magnetic Relaxation Dispersion profiles to 2...
July 22, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28741075/brain-relaxometry-after-macrocyclic-gd-based-contrast-agent
#16
Andreas Müller, Alina Jurcoane, Burkhard Mädler, Philip Ditter, Hans Schild, Elke Hattingen
PURPOSE: To assess if ratios of T1-weighted (T1w) signal intensity (SI) and quantitative T1 relaxometry (qT1) change on serial administration of macrocyclic gadobutrol. METHODS: A total of 17 glioblastoma patients were scanned at 3.0 T magnetic resonance imaging (MRI) every 6 weeks after tumor resection with standard MRI and T1 and T2 relaxometry before and after gadobutrol administration. On co-registered images T1w SI was measured and relaxation times T1 (qT1) and quantitative T2 (qT2) were quantified in several deep grey matter nuclei as ratios relative to frontal white matter and to the pons...
July 24, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28703417/dynamic-nuclear-polarization-fast-field-cycling-method-for-the-selective-study-of-molecular-dynamics-in-block-copolymers
#17
Bulat Gizatullin, Oliver Neudert, Siegfried Stapf, Carlos Mattea
Dynamic nuclear polarization (DNP) is one of the most useful methods to increase sensitivity in NMR spectroscopy. It is based on the transfer of magnetization from an electron to the nuclear spin system. Based on previous work that demonstrated the feasibility of integrating DNP with fast field cycling (FFC) relaxometry and the possibility to distinguish between different mechanisms, such as the Overhauser effect (OE) and the solid effect (SE), the first FFC study of the differential relaxation properties of a copolymer is presented...
July 13, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28699215/automated-t2-relaxometry-of-the-hippocampus-for-temporal-lobe-epilepsy
#18
Gavin P Winston, Sjoerd B Vos, Jane L Burdett, M Jorge Cardoso, Sebastien Ourselin, John S Duncan
OBJECTIVE: Hippocampal sclerosis (HS), the most common cause of refractory temporal lobe epilepsy, is associated with hippocampal volume loss and increased T2 signal. These can be identified on quantitative imaging with hippocampal volumetry and T2 relaxometry. Although hippocampal segmentation for volumetry has been automated, T2 relaxometry currently involves subjective and time-consuming manual delineation of regions of interest. In this work, we develop and validate an automated technique for hippocampal T2 relaxometry...
September 2017: Epilepsia
https://www.readbyqxmd.com/read/28697447/dynamical-regimes-of-lipids-in-additivated-liposomes-with-enhanced-elasticity-a-field-cycling-nmr-relaxometry-approach
#19
Carla C Fraenza, Esteban Anoardo
We study the molecular dynamics of lipids in binary large unilamellar liposomes suspended in D2O composed of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) or soy phosphatidylcholine (SPC) additivated with different percentiles of sodium deoxycholate (SDC). We use the fast field-cycling proton NMR relaxometry technique over a wide timescale and at diverse temperatures. A model previously validated in different formulations is here employed for the relaxometric analysis of elastic vesicles. A new dynamical regime is observed for the first time in additivated DMPC and additivated/non-additivated SPC liposomes...
September 2017: Biophysical Chemistry
https://www.readbyqxmd.com/read/28692849/designing-healthier-comminuted-meat-products-effect-of-dietary-fibers-on-water-distribution-and-texture-of-a-fat-reduced-meat-model-system
#20
Minyi Han, Hanne Christine Bertram
Development of healthier meat products is needed to meet consumers' request. The effects of dietary fiber addition on the water distribution, water binding capacity (WBC), and textural properties of a fat-reduced model meat system enriched with inulin, cellulose, carboxymethyl cellulose (CMC), chitosan, pectin, respectively, were investigated in this study. The fibers were incorporated in powder form to constitute 2% (w/w) of the meat batter. In general, fiber enrichment resulted in significant lower cooking loss and improved WBC, while the impact on texture was dependent on the specific dietary fiber...
July 3, 2017: Meat Science
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