Sphinter of oddi

No abstract text is available yet for this article.

An in vitro isolated spiral strip of rabbit common bile duct was prepared and tested for its pharmacological reactivity. It was found to be a suitable preparation with a long lasting and stable sensitivity when exposed to various drugs. The pharmacological reactivity proved to vary along the common bile duct; the different portions (sphincteric, median and hepatic) displayed different activities to the various agonists and antagonists. The following receptors were identified in different sections: alpha and beta-adrenergic, muscarinic cholinergic, bradykinin, H1 and prostaglandin F2 alpha...

No abstract text is available yet for this article.

Transduodenal sphincteroplasty is an efficient and easy method for dealing with benign biliary tract disease. With it a permanent wide-open stoma is created between the common bile duct and the duodenum, which is established only by complete division of the muscular sphinteric mechanism. Specific indications for sphincteroplasty include multiple common duct stones or "sludge", primary biliary calculi, unremovable intrahepatic stones, impacted ampullary stones, or stenosis of the sphincter of Oddi. Conditions unrelieved by sphincteroplasty include biliary dyskinesia "post-cholecystectomy syndrome", and relapsing pancreatitis with biliary disease...

Pressure changes in the gallbladder and the bile flow and pressure changes in the common bile duct were determined in sheep. The experiments were conducted on animals with external junction of choleslochus and cholecystostomy performed previously. The experiments demonstrated pressure in the sheep of the functional sphincter of Mirizzi at the boundary between the intrahepatic and extrahepatic bile ducts. A correlation was demonstrated also between the function of this sphincter and that of Oddi's sphincter...