keyword
MENU ▼
Read by QxMD icon Read
search

treatment of contusions

keyword
https://www.readbyqxmd.com/read/27903013/isoflurane-associated-mydriasis-mimicking-blown-pupils-in-a-patient-treated-in-a-neurointensive-care-unit
#1
Eva Magdalena Korf, Volker Martin Tronnier, Jan Gliemroth, Jan Nils Küchler
We report a misinterpretation of bilateral mydriasis as blown pupils related to elevated intracranial pressure (ICP) under volatile sedation with isoflurane (Anesthetic Conserving Device [AnaConDa], Hudson RCI, Uppland Vasby, Sweden) in a 59-year-old patient with a severe traumatic brain injury with frontal contusion. The patient showed bilateral mydriasis and a missing light reflex 8 hours after changing sedation from intravenous treatment with midazolam and esketamine to volatile administration of isoflurane...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27888539/macrophage-depletion-impairs-skeletal-muscle-regeneration-the-roles-of-regulatory-factors-for-muscle-regeneration
#2
Xiaoguang Liu, Yu Liu, Linlin Zhao, Zhigang Zeng, Weihua Xiao, Peijie Chen
Though macrophages are essential for skeletal muscle regeneration, which is a complex process, the roles and mechanisms of the macrophages in the process of muscle regeneration are still not fully understood. The objective of this study is to explore the roles of macrophages and the mechanisms involved in the regeneration of injured skeletal muscle. One hundred and twelve C57BL/6 mice were randomly divided into muscle contusion and macrophages depleted groups. Their gastrocnemius muscles were harvested at the time points of 12h, 1, 3, 5, 7, 14d post-injury...
November 26, 2016: Cell Biology International
https://www.readbyqxmd.com/read/27857999/do-age-and-anticoagulants-affect-the-natural-history-of-acute-subdural-hematomas
#3
Brandon P Lucke-Wold, Ryan C Turner, Darnell Josiah, Chelsea Knotts, Sanjay Bhatia
Acute subdural hematoma is a serious complication following traumatic brain injury. Large volume hematomas or those with underlying brain injury can cause mass effect, midline shift, and eventually herniation of the brain. Acute subdural hematomas in the young are associated with high-energy trauma and often have underlying contusions, while acute subdural hematomas in the elderly are associated with minor trauma and an absence of underlying contusions, even though the elderly are more likely to be on anticoagulants or anti-platelet therapy...
2016: Arch Emerg Med Crit Care
https://www.readbyqxmd.com/read/27832687/subarachnoid-space-transplantation-of-schwann-and-or-olfactory-ensheathing-cells-following-severe-spinal-cord-injury-fails-to-improve-locomotor-recovery-in-rats
#4
Mohsen Nategh, Masoumeh Firouzi, Mehdi Naji-Tehrani, Leila Oryadi Zanjani, Zahra Hassannejad, Mohammad Hosein Nabian, Shayan Abdollah Zadegan, Mehrbod Karimi, Vafa Rahimi-Movaghar
Treatment of spinal cord injury by exogenous cells has brought both successful and unsuccessful results. Olfactory ensheathing cells and Schwann cells have been widely used for transplantation purposes. In this study, we investigated the effects of these cells on contused spinal cord by introducing cells into subarachnoid space. Fifty thousand Schwann cells or olfactory ensheathing cells or a mixture of both cell types were transplanted one week after a 3-second clip compression injury at T-9 spinal cord level in rats...
September 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27827332/a-preventative-respiratory-protocol-to-identify-trauma-subjects-at-risk-for-respiratory-compromise-on-a-general-in-patient-ward
#5
Bethany A Nyland, Sarah K Spilman, Meghan E Halub, Keith D Lamb, Julie A Jackson, Trevor W Oetting, Sheryl M Sahr
BACKGROUND: Patients are at risk for respiratory complications after sustaining blunt chest trauma, yet contradictory evidence exists about the utility of prophylactic respiratory therapy to reduce respiratory complications in this population. This study assessed the effectiveness of a proactive respiratory protocol on an in-patient ward to identify trauma patients at risk for pulmonary complications, administer appropriate therapies, and prevent deterioration requiring transfer to the ICU...
December 2016: Respiratory Care
https://www.readbyqxmd.com/read/27800203/surgical-treatment-for-occipital-condyle-fracture-c1-dislocation-and-cerebellar-contusion-with-hemorrhage-after-blunt-head-trauma
#6
Shigeo Ueda, Nobuhiro Sasaki, Miyuki Fukuda, Minoru Hoshimaru
Occipital condyle fractures (OCFs) have been treated as rare traumatic injuries, but the number of reported OCFs has gradually increased because of the popularization of computed tomography (CT) and magnetic resonance imaging (MRI). The patient in this report presented with OCFs and C1 dislocation, along with traumatic cerebellar hemorrhage, which led to craniovertebral junction instability. This case was also an extremely rare clinical condition in which the patient presented with traumatic lower cranial nerve palsy secondary to OCFs...
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27799012/selective-brain-hypothermia-mitigates-brain-damage-and-improves-neurological-outcome-after-posttraumatic-decompressive-craniectomy-in-mice
#7
Jacek Szczygielski, Andreas Müller, Angelika E Mautes, Christoph Sippl, Cosmin Glameanu, Karsten Schwerdtfeger, Wolf-Ingo Steudel, Joachim Oertel
Hypothermia and decompressive craniectomy have been considered as treatment for traumatic brain injury. The present study investigates whether selective brain hypothermia added to craniectomy could improve neurological outcome after brain trauma. Male CD-1 mice were assigned into the following groups: sham, decompressive craniectomy (DC), closed head injury (CHI), CHI followed by craniectomy (CHI+DC), CHI+DC followed by focal hypothermia (CHI+DC+H). At 24h posttrauma animals were subjected to Neurological Severity Score test (NSS) and Beam Balance Score test (BBS)...
October 31, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27789279/conditioned-medium-of-olfactory-ensheathing-cells-promotes-the-functional-recovery-and-axonal-regeneration-after-contusive-spinal-cord-injury
#8
Mengchao Gu, Zhengchao Gao, Xiaohui Li, Lei Guo, Teng Lu, Yuhuan Li, Xijing He
OBJECTIVE: To investigate the effectiveness and the potential role of olfactory ensheathing cell conditioned medium (OEC-M) to treat contusive spinal cord injury (SCI). METHODS: The contusive SCI model was established by NYU weight-drop impactor at T10 segment. Male Sprague-Dawley rats received intraperitoneal injection of control medium (Con-M, n=18), low dose OEC-M (n=18) and high dose OEC-M (n=18). Immunofluorescence was performed to identify the purity of cultured OECs...
January 1, 2017: Brain Research
https://www.readbyqxmd.com/read/27762660/time-dependent-effects-of-arginine-vasopressin-v1-receptor-inhibition-on-secondary-brain-damage-after-traumatic-brain-injury
#9
Sandro M Krieg, Raimund Trabold, Nikolaus Plesnila
Arginine-vasopressin (AVP) V1 receptors are known to mediate brain edema formation after traumatic brain injury (TBI). So far, however, AVP V1 receptors were only inhibited by genetic deletion or prior to trauma. Therefore the current study aimed to determine the therapeutic window of AVP V1 receptors anatomization after TBI. Male C57BL/6 mice (n=7 per group) were subjected to controlled cortical impact (CCI) and 500 ng of a selective peptide V1 receptor antagonist (V1880) were applied by intracerebroventricular injection 5 min, 1, 3, and 6 hours thereafter...
October 20, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27762659/neurobiological-effects-of-morphine-following-spinal-cord-injury
#10
Michelle Hook, Sarah Woller, Eric Bancroft, Miriam Aceves, Mary Katherine Funk, John Hartman, Sandra M Garraway
Opioids and NSAIDs are commonly used to manage pain in the early phase of spinal cord injury (SCI). Despite its analgesic efficacy, however, our studies suggest that intrathecal (i.t.) morphine undermines locomotor recovery and increases lesion size in a rodent model of SCI. Similarly, intravenous (i.v.) morphine attenuates locomotor recovery. The current study explores whether i.v. morphine also increases lesion size after a spinal contusion (T12) injury, and quantifies the cell types that are affected by early opioid administration...
October 20, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27761681/diadenosine-tetraphosphate-ap4a-inhibits-atp-induced-excitotoxicity-a-neuroprotective-strategy-for-traumatic-spinal-cord-injury-treatment
#11
David Reigada, Rosa María Navarro-Ruiz, Marcos Javier Caballero-López, Ángela Del Águila, Teresa Muñoz-Galdeano, Rodrigo M Maza, Manuel Nieto-Díaz
Reducing cell death during the secondary injury is a major priority in the development of a cure for traumatic spinal cord injury (SCI). One of the earliest processes that follow SCI is the excitotoxicity resulting from the massive release of excitotoxicity mediators, including ATP, which induce an excessive and/or prolonged activation of their receptors and a deregulation of the calcium homeostasis. Diadenosine tetraphosphate (Ap4A) is an endogenous purinergic agonist, present in both extracellular and intracellular fluids, with promising cytoprotective effects in different diseases including neurodegenerative processes...
October 19, 2016: Purinergic Signalling
https://www.readbyqxmd.com/read/27744073/does-decorin-protect-neuronal-tissue-via-its-antioxidant-and-antiinflammatory-activity-from-traumatic-brain-injury-an-experimental-study
#12
Rafet Özay, Erhan Türkoğlu, Bora Gürer, Habibullah Dolgun, Oya Evirgen, Berrin İmge Ergüder, Nazlı Hayırlı, Levent Gürses, Zeki Şekerci, Erdal Reşit Yılmaz
BACKGROUND: The development of secondary brain injury via oxidative stress after traumatic brain injury (TBI) is well known. Decorin inactivates Transforming growth factor-β1 (TGF-β1), complement system (CS) and Tumor necrosis factor-α (TNF-α) which are related the oxidative stress and apoptosis. Consequently, the aim of the present study was to evaluate the role of Decorin (DC) on TBI. METHODS: A total of 24 male rats were used and divided into four groups as follows; control, trauma, DC, and methylprednisolone (MP)...
October 12, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27736318/norbni-blocks-the-adverse-effects-of-morphine-following-spinal-cord-injury
#13
Miriam Aceves, Eric Bancroft, Alejandro R Aceves, Michelle Hook
Opioids are frequently used for the treatment of pain following spinal cord injury (SCI). Unfortunately, we have shown that morphine administered in the acute phase of SCI results in significant, adverse secondary consequences including compromised locomotor and sensory recovery. Similarly, we showed that selective activation of the κ-opioid receptor (KOR), even at a dose 32-fold lower than morphine, is sufficient to attenuate recovery of locomotor function. In the current study, we tested whether activation of the KOR is necessary to produce morphine's adverse effects using nor-Binaltorphimine (norBNI), a selective KOR antagonist...
October 13, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27723516/characterization-of-the-occult-nature-of-injury-for-frequently-occurring-motor-vehicle-crash-injuries
#14
Samantha L Schoell, Andrea N Doud, Ashley A Weaver, Jennifer W Talton, Ryan T Barnard, James E Winslow, Joel D Stitzel
BACKGROUND: Occult injuries are not easily detected and can be potentially life-threatening. The purpose of this study was to quantify the perceived occultness of the most frequent motor vehicle crash injuries according to emergency medical services (EMS) professionals. STUDY DESIGN: An electronic survey was distributed to 1,125 EMS professionals who were asked to quantify the likelihood that first responders would miss symptoms related to a particular injury on a 5-point Likert scale...
October 7, 2016: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/27693821/post-traumatic-tremor-and-thalamic-deep-brain-stimulation-evidence-for-use-of-diffusion-tensor-imaging
#15
Sandra G J Boccard, Pedro Rebelo, Binith Cheeran, Alexander Green, James J FitzGerald, Tipu Z Aziz
BACKGROUND: Deep brain stimulation (DBS) is a well-established treatment to reduce tremor, notably in Parkinson disease. DBS may also be effective in post-traumatic tremor, one of the most common movement disorders caused by head injury. However, the cohorts of patients often have multiple lesions that may impact the outcome depending on which fiber tracts are affected. CASE DESCRIPTION: A 20-year-old man presented after road traffic accident with severe closed head injury and polytrauma...
September 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27692838/pulmonary-contusion-and-traumatic-pneumatoceles-in-a-platform-diver-with-hemoptysis
#16
Joanna Shi-En Chan, Jeremy C Wee, R Ponampalam, Evelyn Wong
BACKGROUND: Injuries in divers resulting purely from impact with the water are uncommon in the published literature. We present a case report of pulmonary contusion in a young diver. CASE REPORT: A young, healthy competitive platform diver landed flat on his back in the water from a dive of 10 meters. He complained of upper back pain and had an episode of hemoptysis after the dive. He was initially observed for 15 hours postinjury, and was discharged when three chest radiographs (CXRs) taken at 1, 7, and 11 hours postinjury did not show significant abnormalities...
September 28, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27689421/diffusion-tensor-imaging-as-a-biomarker-for-assessing-neuronal-stem-cell-treatments-affecting-areas-distal-to-the-site-of-spinal-cord-injury
#17
Michael B Jirjis, Chris Valdez, Aditya Vedantam, Brian D Schmit, Shekar N Kurpad
OBJECTIVE The aims of this study were to determine if the morphological and functional changes induced by neural stem cell (NSC) grafts after transplantation into the rodent spinal cord can be detected using MR diffusion tensor imaging (DTI) and, furthermore, if the DTI-derived mean diffusivity (MD) metric could be a biomarker for cell transplantation in spinal cord injury (SCI). METHODS A spinal contusion was produced at the T-8 vertebral level in 40 Sprague Dawley rats that were separated into 4 groups, including a sham group (injury without NSC injection), NSC control group (injury with saline injection), co-injection control group (injury with Prograf), and the experimental group (injury with NSC and Prograf injection)...
September 30, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27668913/interventricular-septal-pseudoaneurysm-after-blunt-chest-trauma-in-a-6-year-old-an-illustrative-case-and-review
#18
Natalie Behrle, Peter Dyke, Abdallah Dalabih
Motor vehicle accident is the most common cause of blunt cardiac injury (BCI) in children (85.3%) due to the height of the child in relation to proper restraints and the compliant pediatric rib cage (J Trauma. 1996;40:200-202). Trauma to the chest wall may lead to injury of the myocardium, resulting in myocardial contusion, ventricular septal defect (VSD), ventricular free wall rupture, or valve compromise (J Trauma. 1996;40; 200-202; Heart Lung. 2012;41:200-202; J Inj Violence Res. 2012;4:98-100). There are several proposed mechanisms for the formation of VSD after blunt chest trauma including rupture of ischemic myocardium related to the initial trauma and reopening of a spontaneously closed congenital VSD...
September 23, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27665217/therapeutic-pulsed-ultrasound-promotes-revascularization-and-functional-recovery-of-rat-skeletal-muscle-after-contusion-injury
#19
Areeya Chongsatientam, Tossaporn Yimlamai
The mechanism by which therapeutic pulsed ultrasound (TPU) promotes the repair of damaged gastrocnemius muscle was investigated. Male Wistar rats were divided into uninjured, sham-treated injured and TPU-treated injured (TPU) groups. Injury was induced by mass-drop technique. TPU was applied to the injured muscle for 5 min, daily, started at day 1 post-injury and continuing for 3, 7 and 14 d. For 3 d post-injury, a significant reduction in muscle force was observed in both the sham-treated injured and TPU groups...
December 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27661034/long-term-therapeutic-outcome-of-ophthalmic-complications-following-endoscopic-sinus-surgery
#20
Heping Wu, Tao Shen, Jingchang Chen, Jianhua Yan
Ophthalmic complications associated with endoscopic sinus surgery (ESS) are quite rare. There is a paucity of reliable data and limited experience on the clinical findings and treatments of these injuries. Our study here is to characterize the types of orbital injury following ESS, in particular extraocular muscle injury, and to evaluate the long-term therapeutic outcomes as compiled from a relatively large sample of Chinese patients.A series of 27 patients (21 males and 6 females; mean age = 42.6 years, ranges: 10-60 years) were retrospectively reviewed...
September 2016: Medicine (Baltimore)
keyword
keyword
106371
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"