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https://www.readbyqxmd.com/read/28497312/phenytoin-neuroprotection-or-neurotoxicity
#1
REVIEW
Jan M Keppel Hesselink, David J Kopsky
Phenytoin is an 80-year young molecule and new indications are still emerging. The neuroprotective potential of phenytoin has been evaluated for decades. Recently, a positive phase II trial supported its further development in the treatment of optic neuritis in multiple sclerosis. In 1942, however, peripheral neuritis was first reported to be an adverse event of phenytoin, and since then a small but steady stream of publications discussed peripheral polyneuropathy as being a possible adverse event of phenytoin...
May 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28495480/-fabien-arcelin-1876-1942-or-how-to-become-a-radiation-oncologist-when-born-an-archeologist
#2
N Foray
Fabien Arcelin, physician working in Lyon, pioneer of radiology and radiotherapy, was both mentored by Destot (one of the fathers of the French radiology for his thesis of medicine) and by his own father Adrien Arcelin (one of the two codiscoverers of the prehistorical site of the Roche-de-Solutré in Burgundy) for archeological works. Hence, radiologist in Lyon during the week and archeologist during the weekend, Fabien Arcelin made significant advances in both radiation research and archeology. He was notably the discoverer of the first tombs of Aurignacian men...
May 8, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28492447/the-yellow-fever-vaccine-misadventure-of-1942
#3
John S Marr, John T Cathey
In 1942, a hepatitis B outbreak occurred in the US Army after vaccination with contaminated lots of 17D yellow fever vaccine; long-term sequelae were surprisingly limited, and retrospective studies of carrier rates, cirrhosis, and hepatocellular carcinoma were found to be minimal. Later studies identified the contaminant as hepatitis B virus (HBV) in the human serum component of the vaccine. Other than 2 follow-up studies of long-term sequelae and reports within US Military archives, the event has never been fully elucidated in its proper historical context in the medical literature available through MEDLINE (PubMed)...
May 10, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28490663/quantitative-estimated-exposure-to-vinyl-chloride-and-risk-of-angiosarcoma-of-the-liver-and-hepatocellular-cancer-in-the-us-industry-wide-vinyl-chloride-cohort-mortality-update-through-2013
#4
Kenneth A Mundt, Linda D Dell, Lori Crawford, Alexa E Gallagher
OBJECTIVE: To evaluate mortality risks of angiosarcoma of the liver (ASL), primary hepatocellular carcinoma (HCC) and other cancers among 9951 men employed between 1942 and 1972 at 35 US vinyl chloride (VC) or polyvinyl chloride plants followed for mortality through 31 December 2013. METHODS: SMR and time-dependent Cox proportional hazards analyses were used to evaluate mortality risks by cumulative VC exposure. RESULTS: Liver cancer mortality was elevated (SMR=2...
May 10, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28466454/renal-osteodystrophy-time-for-common-nomenclature
#5
REVIEW
Susan M Ott
PURPOSE OF REVIEW: The term renal osteodystrophy has been used to describe a wide variety of bone problems facing patients with chronic kidney disease (CKD). Here, we review the history of the use of this term. RECENT FINDINGS: Bone disease resulting from CKD was first noticed in 1890. The term "renal osteodystrophy" was used to define the bone disease in 1942. Since then, important discoveries have increased our knowledge of the complexities of bone physiology in these patients...
May 2, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28463010/behavioral-patterns-and-associations-with-glucose-control-during-12-week-randomized-free-living-clinical-trial-of-day-and-night-hybrid-closed-loop-insulin-delivery-in-adults-with-type-1-diabetes
#6
Ali Emami, Malgorzata E Willinska, Hood Thabit, Lalantha Leelarathna, Sara Hartnell, Sibylle Dellweg, Carsten Benesch, Julia K Mader, Manuel Holzer, Harald Kojzar, Thomas R Pieber, Sabine Arnolds, Mark L Evans, Roman Hovorka
OBJECTIVES: We evaluated patterns of meal intake, insulin bolus delivery, and fingerstick glucose measurements during hybrid closed-loop and sensor-augmented pump (SAP) therapy, including associations with glucose control. METHODS: Data were retrospectively analyzed from pump-treated adults with type 1 diabetes who underwent, in random order, 12 weeks free-living closed-loop (n = 32) and 12 weeks SAP (n = 33) periods. We quantified daily patterns of main meals, snacks, prandial insulin boluses, correction boluses, and fingerstick glucose measurements by analyzing data recorded on the study glucometer and on study insulin pump...
May 2, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28458793/osteosarcoma-of-the-larynx-treatment-outcomes-and-patterns-of-failure-analysis
#7
Nathan R Bennion, Michael J Baine, Timothy Malouff, Weining Zhen
The incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most recent case of laryngeal osteosarcoma in a patient presenting with respiratory distress found to be due to a tumor mass arising from her cricoid cartilage. We further summarize current knowledge regarding the epidemiology, presentation, and diagnosis of this uncommon disease...
March 24, 2017: Rare Tumors
https://www.readbyqxmd.com/read/28426782/peste-des-petits-ruminants-ppr-a-neglected-tropical-disease-in-maghreb-region-of-north-africa-and-its-threat-to-europe
#8
Ratiba Baazizi, Mana Mahapatra, Brian Donald Clarke, Khatima Ait-Oudhia, Djamel Khelef, Satya Parida
BACKGROUND: Peste des petits ruminants (PPR) is a contagious disease listed by the World Organisation for Animal health (OIE) as being a specific hazard. It affects sheep, goats, and wild ungulates, and is prevalent throughout the developing world particularly Asia, the Middle East, and Africa. PPR has been targeted for eradication by 2030 by the Food and Agriculture Organization of the United Nations (FAO) and the OIE, after the successful eradication of the related disease, rinderpest in cattle...
2017: PloS One
https://www.readbyqxmd.com/read/28422888/18f-fdg-pet-ct-for-detection-of-the-primary-tumor-in-adults-with-extracervical-metastases-from-cancer-of-unknown-primary-a-systematic-review-and-meta-analysis
#9
REVIEW
Synne Alexandra Burglin, Søren Hess, Poul Flemming Høilund-Carlsen, Oke Gerke
BACKGROUND: Cancer of unknown primary (CUP) is a heterogeneous group of cancers, so called when a biopsy from a patient reveals malignancy without giving a clue to where in the body the primary tumor is located. Whole-body 18-fluorine-fluorodeoxyglucose positron-emission-tomography/computed tomography (18F-FDG PET/CT) is widely used for diagnosis and staging of most cancers. We hypothesized that 18F-FDG PET/CT-especially if used early-is suitable for the detection of the primary tumor in patients with CUP...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28405215/the-american-psychosomatic-society-integrating-mind-brain-body-and-social-context-in-medicine-since-1942
#10
REVIEW
Christoph Herrmann-Lingen
BACKGROUND: The American Psychosomatic Society is one of the oldest and probably the most influential scientific society in psychosomatic/biopsychosocial research worldwide. The current article delineates the historical development and current strategic orientation of the society. METHOD: Review of published literature, archived materials and current documents of the society. RESULTS: The American Psychosomatic Society (APS) was founded in 1942, originally named the "American Society for Research in Psychosomatic Problems "...
2017: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/28403312/nursing-throughout-war-times-political-propaganda-and-professional-valorization-1942-1945
#11
Thais da Silva Kneodler, Graciele Oroski Paes, Fernando Rocha Porto, Pedro Ruiz Barbosa Nassar, Alexandre Barbosa de Oliveira
OBJECTIVE: to discuss the symbolic effects of the publication on written press of institutional rites related to the courses promoted by the Brazilian Federal District's Schools of Nursing during the Second World War. METHOD: exploratory and documentary study, whose sources were treated by historical method. RESULTS: one noticed, in the news reports analyzed, that the Brazilian Estado Novo has used nurses images to divulge within the society the woman's acting altruistic model in service to the country, through the systematic diffusion by the press of her honorable acting during the war, what assured the amplification of the visibility and acknowledgment of the Nursing profession in that context...
April 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28392651/degos-like-lesions-associated-with-systemic-lupus-erythematosus
#12
Min Soo Jang, Jong Bin Park, Myeong Hyeon Yang, Ji Yun Jang, Joon Hee Kim, Kang Hoon Lee, Geun Tae Kim, Hyun Hwangbo, Kee Suck Suh
Degos disease, also referred to as malignant atrophic papulosis, was first described in 1941 by Köhlmeier and was independently described by Degos in 1942. Degos disease is characterized by diffuse, papular skin eruptions with porcelain-white centers and slightly raised erythematous telangiectatic rims associated with bowel infarction. Although the etiology of Degos disease is unknown, autoimmune diseases, coagulation disorders, and vasculitis have all been considered as underlying pathogenic mechanisms. Approximately 15% of Degos disease have a benign course limited to the skin and no history of gastrointestinal or central nervous system (CNS) involvement...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28384641/inception-and-development-of-the-papanicolaou-stain-method
#13
Nikolaos Chantziantoniou, Amber D Donnelly, Maheswari Mukherjee, Mathilde E Boon, R Marshall Austin
OBJECTIVE: Cytodiagnoses of specific malignancies are enabled through analyses of abnormal nuclear chromatin and cytoplasmic features in stained cells. AIM: The objective of this work was to explore the inception, development, and chemistry of the Pap stain method introduced in 1942 by Dr. G.N. Papanicolaou. STUDY DESIGN: To achieve this, we carried out a review of the English literature. RESULTS: Between 1914 and 1933, Papanicolaou first analyzed vaginal squamous cells in guinea pigs and later in human vaginal fluid samples using hematoxylin and eosin with limited color reactions, correlating the cell-type morphology with endocrinology and histology...
April 7, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28348369/novel-molecular-approach-to-define-pest-species-status-and-tritrophic-interactions-from-historical-bemisia-specimens
#14
W T Tay, S Elfekih, A Polaszek, L N Court, G A Evans, K H J Gordon, P J De Barro
Museum specimens represent valuable genomic resources for understanding host-endosymbiont/parasitoid evolutionary relationships, resolving species complexes and nomenclatural problems. However, museum collections suffer DNA degradation, making them challenging for molecular-based studies. Here, the mitogenomes of a single 1912 Sri Lankan Bemisia emiliae cotype puparium, and of a 1942 Japanese Bemisia puparium are characterised using a Next-Generation Sequencing approach. Whiteflies are small sap-sucking insects including B...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28329522/multiple-miliary-osteoma-cutis-of-the-face-associated-with-albright-hereditary-osteodystrophy-in-the-setting-of-acne-vulgaris-a-case-report
#15
Joseph V Caravaglio, Rema Gupta, David Weinstein
Osteoma cutis is a condition characterized by theformation of bone within the skin. Such aberrantossification of the skin and subcutaneous tissue isconsidered primary when it arises in the absence ofunderlying tissue damage or a preceding cutaneouslesion. Conversely, secondary osteoma cutis occurswhen skin ossification is the result of a pre-existingskin lesion, trauma, or inflammatory process [1,2].Although rare, primary osteoma cutis has beenassociated with a number of different geneticdisorders. Albright hereditary osteodystrophy (AHO),a condition first described in 1942 by Fuller Albright,is an autosomal dominant metabolic disorder causedby a mutation in the GNAS1 gene [3]...
March 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28264352/the-jumping-plant-lice-of-the-neotropical-genus-i-tainarys-i-hemiptera-psylloidea-associated-with-anacardiaceae
#16
Daniel Burckhardt, Dalva L Queiroz
The Neotropical psyllid genus Tainarys Brèthes, 1920 is revised to include 14 extant and one fossil species from Dominican amber. Eight species are described as new, viz. Tainarys aroeira sp. nov., T. atra sp. nov., T. hapla sp. nov., T. myracrodrui sp. nov., T. nigricornis sp. nov., T. didyma sp. nov. and T. orientalis sp. nov. from Brazil, the last two also from Uruguay, as well as T. lozadai sp. nov. from Peru. The fifth instar immatures are described for nine species. †Vicinilura Klimaszewski, 1996, erected for the fossil †V...
February 20, 2017: Zootaxa
https://www.readbyqxmd.com/read/28264308/description-of-the-newly-hatched-juvenile-of-i-aegla-i-i-castro-i-schmitt-1942-crustacea-anomura-aeglidae
#17
Luane Samara Alves E Silva, Cecilia Margarita Guerrero-Ocampo, Maria Lucia Negreiros-Fransozo, Gustavo Monteiro Teixeira
This study describes and illustrates the morphology of the first juvenile stage of Aegla castro Schmitt, 1942. Ovigerous females were collected from May to July 2013, in Couro River (Mauá da Serra, Paraná, Brazil). These females were kept individually under controlled feeding, aeration, water temperature and quality and checked daily for hatching of juveniles. The newly-hatched juveniles were fixed in alcohol series and kept in 70% alcohol with glycerin in a 2:1 ratio prior to study under light microscopy...
February 26, 2017: Zootaxa
https://www.readbyqxmd.com/read/28248665/douglas-doug-dorset-1942-2016
#18
Lisa Baugh, Mark Disko, William Lamberti, Karl Strohmaier, William Duax, John Fryer, Sven Hovmöller, Xiaodong Zou, Laurence Marks, Stavros Nicolopoulos
No abstract text is available yet for this article.
March 1, 2017: Acta Crystallographica. Section A, Foundations and Advances
https://www.readbyqxmd.com/read/28230130/stephen-e-fienberg-1942-2016
#19
Robin Mejia
No abstract text is available yet for this article.
February 22, 2017: Nature
https://www.readbyqxmd.com/read/28225542/historical-overview-of-leprosy-control-in-cuba
#20
Enrique Beldarraín-Chaple
INTRODUCTION Leprosy, an infectious disease caused by Mycobacterium leprae, affects the nervous system, skin, internal organs, extremities and mucous membranes. Biological, social and environmental factors influence its occurrence and transmission. The first effective treatments appeared in 1930 with the development of dapsone, a sulfone. The main components of a control and elimination strategy are early case detection and timely administration of multidrug therapy. OBJECTIVES Review the history of leprosy control in Cuba, emphasizing particularly results of the National Leprosy Control Program, its modifications and influence on leprosy control...
January 2017: MEDICC Review
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