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https://www.readbyqxmd.com/read/28927679/-mediastinitis-after-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#1
D Basille, F De Dominicis, E Magois, C Andrejak, P Berna, V Jounieaux
INTRODUCTION: Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used for the diagnosis of mediastinal and hilar lymphadenopathy. OBSERVATION: We describe a case of mediastinitis appearing 15 days after an EBUS-TBNA procedure in a 79 years old male patient. The mediastinitis was treated surgically by thoracotomy with a wide excision of infected tissue requiring transplantation of a serratus anterior muscle flap pedicled on a branch of the thoracodorsal artery...
September 16, 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/28926605/assessment-of-common-somatic-mutations-of-egfr-kras-braf-nras-in-pulmonary-non-small-cell-carcinoma-using-iplex%C3%A2-hs-a-new-highly-sensitive-assay-for-the-massarray%C3%A2-system
#2
Bobbie C Sutton, Ryan T Birse, Kevin Maggert, Tammy Ray, Jessica Hobbs, Amobi Ezenekwe, Jason Kazmierczak, Michael Mosko, Joan Kish, Andrew Bullock, Zonggao Shi, M Sharon Stack, Darryl Irwin
Increased early detection and personalized therapy for lung cancer have coincided with greater use of minimally invasive sampling techniques such as endobronchial ultrasound-guided biopsy (EBUS), endoscopic ultrasound-guided biopsy (EUS), and navigational biopsy, as well as thin needle core biopsies. As many lung cancer patients have late stage disease and other comorbidities that make open surgical procedures hazardous, the least invasive biopsy technique with the highest potential specimen yield is now the preferred first diagnostic study...
2017: PloS One
https://www.readbyqxmd.com/read/28924107/transesophageal-endoscopic-ultrasound-eus-guided-fine-needle-aspiration-for-the-diagnosis-of-a-lung-nodule-that-was-non-abutting-on-ct
#3
Yousuke Nakai, Hiroyuki Isayama, Takeo Watanabe, Suguru Mizuno, Hirofumi Kogure, Saburo Matsubara, Minoru Tada, Kazuhiko Koike
An 80-year-old man presented with a right side lung tumor. The tumor was not abutting the bronchus or chest wall; thus, endobronchial ultrasound (EBUS) and CT-guided biopsy were considered to be technically difficult. We therefore attempted endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Although the nodule was not abutting the esophagus on CT, an irregularly shaped hypoechoic lesion was visualized on EUS. EUS-FNA was successfully performed. The tumor was diagnosed as squamous cell carcinoma...
September 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28910804/ebus-tbna-can-distinguish-sarcoid-like-side-effect-of-nivolumab-treatment-from-tumor-progression-in-non-small-cell-lung-cancer
#4
Ségolène Lainez, Claire Tissot, Michèle Cottier, Jean-Michel Vergnon
With the expansion of immunotherapy in the treatment of lung cancer, clinicians have to face new clinical pictures and adapt their practice. We report the case of a 69-year-old man diagnosed with non-small cell lung cancer using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and treated with nivolumab as second-line therapy. After 8 injections of nivolumab, a new CT and PET scan revealed massive growth and increase in metabolism of hilar and mediastinal lymph nodes, whereas the size and metabolism of the left upper lobe lesion were reduced...
September 15, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28898881/performance-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-for-the-diagnosis-of-isolated-mediastinal-and-hilar-lymphadenopathy
#5
Chung-Chun Tyan, Tiago Machuca, Kasia Czarnecka, Hyang Mi Ko, Gilda da Cunha Santos, Scott L Boerner, Andrew Pierre, Marcelo Cypel, Tom Waddell, Gail Darling, Marc de Perrot, Shaf Keshavjee, William Geddie, Kazuhiro Yasufuku
BACKGROUND: Although many studies have assessed the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the context of a specific disease, few studies have assessed the overall diagnostic yield, sensitivity, and negative predictive value in patients with isolated mediastinal and hilar lymphadenopathy (IMHL). OBJECTIVE: We evaluated the performance of EBUS-TBNA for diagnosing IMHL in a population with a high prevalence of concurrent or preexisting non-pulmonary malignancy...
September 13, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28881088/ectopic-thyroid-cancer-diagnosed-by-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#6
Jingwen Hu, Ming Li, Lin Xu
We report a case of papillary carcinoma in a mediastinal ectopic thyroid diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). In this case, the tumor was adjacent to the central airway; therefore, we attempted to perform EBUS-TBNA to obtain specimens for a diagnosis of papillary thyroid carcinoma. Surgical resection was conducted, and histological evaluation of the resected specimen confirmed ectopic papillary thyroid carcinoma, consistent with the histology from the EBUS-TBNA specimen...
September 7, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28879863/a-novel-stepwise-approach-combining-conventional-and-endobronchial-ultrasound-needle-aspiration-for-mediastinal-lymph-node-sampling
#7
Levy Liran, Kuint Rottem, Fridlender Zvi Gregorio, Abutbul Avi, Berkman Neville
BACKGROUND AND OBJECTIVES: Since the introduction of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), most pulmonary centers use this technique exclusively for mediastinal lymph node (LN) sampling. Conventional "blind" TBNA (cTBNA), however, is cheaper, more accessible, provides more tissue, and requires less training. We evaluated whether sampling of mediastinal LN using EBUS-TBNA or cTBNA according to a predefined set of criteria provides acceptable diagnostic yield...
September 7, 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28879075/endobronchial-ultrasound-convex-probe-for-lymphoma-sarcoidosis-lung-cancer-and-other-thoracic-entities-a-case-series
#8
Paul Zarogoulidis, Haidong Huang, Chong Bai, Christoforos Kosmidis, Georgia Trakada, Lemonia Veletza, Theodora Tsiouda, Nikolaos Barbetakis, Dimitrios Paliouras, Evangelia Athanasiou, Dimitris Hatzibougias, Anastasios Kallianos, Nikolaos Panagiotopoulos, Liana Papaemmanouil, Wolfgang Hohenforst-Schmidt
Endobronchial ultrasound endoscopy is a state of the art diagnostic endoscopic procedure for the thorax. Firstly it was designed mainly for the staging of lung cancer and of course for the diagnosis of suspicious findings in large central airways. The main limitation of the equipment is the diameter of the instrument and therefore it can only be guided through large airways. However; the diameter of the working channel also provides a large tissue sample nowadays with the 19G biopsy needle. We will provide our experience with the 22G needle of the endobronchial convex-probe in several medical situations of the thorax...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28869237/nasal-route-for-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna-an-alternative-modality-in-difficult-oral-bronchoscope-insertion
#9
Saurabh Mittal, Karan Madan, Vijay Hadda, Anant Mohan, Randeep Guleria
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is usually performed under moderate sedation through the oral approach. Oral insertion is performed owing to the larger size of the EBUS bronchoscope as well as the delicate and rigid distal end with an integrated ultrasound transducer assembly. Nasal route for EBUS scope insertion has been described as a feasible alternative. We herein report a patient wherein inability to introduce the EBUS bronchoscope through the mouth necessitated nasal insertion of the bronchoscope to successfully perform EBUS-TBNA...
September 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28867308/-use-of-endobronchial-ultrasound-in-the-management-of-cryptogenic-haemoptysis
#10
L Mhanna, E Noel-Savina, S Pontier, M Jaffro, N Guibert, C Hermant, G Plat, A Didier
Currently about 50% of cases of haemoptysis are thought to be cryptogenic. Haemorrhage from the pulmonary arterial system is rare and usually due to aneurysms or pseudoaneurysms, the radiological diagnosis of which is often difficult. We report here the case of a patient admitted with a heavy haemoptysis in whom the thoracic CT scan did not reveal the diagnosis. Bronchoscopy with endobronchial ultrasound showed a vascular malformation of a branch of the pulmonary artery allowing a radiological embolisation...
August 31, 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/28864395/bronchoscopic-techniques-in-the-management-of-patients-with-tuberculosis
#11
REVIEW
Michele Mondoni, Alice Repossi, Paolo Carlucci, Stefano Centanni, Giovanni Sotgiu
Tuberculosis (TB) is one of the leading causes of morbidity and mortality worldwide. Early diagnosis and treatment are key to prevent Mycobacterium tuberculosis transmission. Bronchoscopy can play a primary role in pulmonary TB diagnosis, particularly for suspected patients with scarce sputum or sputum smear negativity, and with endobronchial disease. Bronchoscopic needle aspiration techniques are accurate and safe means adopted to investigate hilar and mediastinal lymph nodes in cases of suspected TB lymphadenopathy...
August 29, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28857370/refining-the-role-of-endobronchial-ultrasound-transbronchial-needle-aspiration-in-lung-cancer-staging
#12
EDITORIAL
Phan Nguyen
No abstract text is available yet for this article.
August 30, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28857362/diagnostic-performance-of-endobronchial-ultrasound-guided-mediastinal-lymph-node-sampling-in-early-stage-non-small-cell-lung-cancer-a-prospective-study
#13
Macarena R Vial, Oisin J O'Connell, Horiana B Grosu, Mike Hernandez, Laila Noor, Roberto F Casal, John Stewart, Mona Sarkiss, Carlos A Jimenez, David Rice, Reza Mehran, David E Ost, George A Eapen
BACKGROUND AND OBJECTIVE: Standard nodal staging of lung cancer consists of positron emission tomography/computed tomography (PET/CT), followed by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) if PET/CT shows mediastinal lymphadenopathy. Sensitivity of EBUS-TBNA in patients with N0/N1 disease by PET/CT is unclear and largely based on retrospective studies. We assessed the sensitivity of EBUS-TBNA in this setting. METHODS: We enrolled patients with proven or suspected lung cancer staged as N0/N1 by PET/CT and without metastatic disease (M0), who underwent staging EBUS-TBNA...
August 30, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28840019/bronchoscopy-with-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-vs-transthoracic-needle-aspiration-in-lung-cancer-diagnosis-and-staging
#14
Mark L Munoz, Noah Lechtzin, Qing Kay Li, KoPen Wang, Lonny B Yarmus, Hans J Lee, David J Feller-Kopman
BACKGROUND: In evaluating patients with suspected lung cancer, it is important to not only obtain a tissue diagnosis, but also to obtain enough tissue for both histologic and molecular analysis in order to appropriately stage the patient with a safe and efficient strategy. The diagnostic approach may often be dependent on local resources and practice patterns rather than current guidelines. We Describe lung cancer staging at two large academic medical centers to identify the impact different procedural approaches have on patient outcomes...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28840013/training-and-certification-in-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#15
REVIEW
Therese Maria Henriette Naur, Lars Konge, Leizl Joy Nayahangan, Paul Frost Clementsen
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) plays a key role in the staging of lung cancer, which is crucial for allocation to surgical treatment. EBUS-TBNA is a complicated procedure and simulation-based training is helpful in the first part of the long learning curve prior to performing the procedure on actual patients. New trainees should follow a structured training programme consisting of training on simulators to proficiency as assessed with a validated test followed by supervised practice on patients...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28839991/combination-of-virtual-bronchoscopic-navigation-endobronchial-ultrasound-and-rapid-on-site-evaluation-for-diagnosing-small-peripheral-pulmonary-lesions-a-prospective-phase-ii-study
#16
Toshiya Maekura, Chikatoshi Sugimoto, Akihiro Tamiya, Nobuhiko Saijo, Yoko Naoki, Taro Koba, Yohei Kimura, Yoshinobu Matsuda, Masaki Kanazu, Naoko Takeuchi, Yumiko Sasaki, Yujiro Naito, Taisuke Tsuji, Reiko Sugawara, Takehiko Kobayashi, Keiko Nakao, Yoshihiko Taniguchi, Kyoichi Okishio, Naoki Omachi, Takahiko Kasai, Shinji Atagi
BACKGROUND: The diagnostic yield of peripheral pulmonary lesions (PPLs) by flexible bronchoscopy (FB) is still insufficient. To improve the diagnostic yield of bronchoscopy, several techniques such as endobronchial ultrasound (EBUS), virtual bronchoscopic navigation (VBN), and rapid on-site evaluation (ROSE) have been examined. The primary purpose of the present study was to evaluate the usefulness of combining EBUS, VBN, and ROSE for diagnosing small PPLs. METHODS: Patients with PPLs 30 mm or less on chest computed tomography (CT) were prospectively enrolled...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28834894/value-of-radial-probe-endobronchial-ultrasound-guided-transbronchial-biopsy-and-computer-tomography-guided-transthoracic-needle-aspiration-in-the-diagnosis-of-peripheral-pulmonary-lesions
#17
Qiudi Zhang, Sujuan Zhang, Xiong Xu, Qianqian Xu, Jun Zhou
Computer tomography-guided transthoracic needle aspiration (CT-TTNA) is a minimally invasive technique for sampling peripheral lung lesions. Radial endobronchial ultrasound-guided transbronchial biopsy (rEBUS-TBB) is an alternative. The present study analyzed and compared rEBUS-TBB and CT-TTNA in the diagnosis of peripheral pulmonary lesions (PPL).Clinical data of 513 patients with PPL who underwent an rEBUS-TBB or CT-TTNA examination were analyzed retrospectively. The positive diagnostic rate, complication rate, and influencing factors of the 2 methods were compared...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28834344/unusual-presentation-of-poorly-differentiated-primary-pulmonary-synovial-sarcoma-pd-ppss-diagnosed-by-ebus-tbna-with-cytogenetic-confirmation-a-diagnostic-challenge
#18
Sharvari Dalal, Charles E Nicholson, Darshana Jhala
Poorly differentiated primary pulmonary synovial sarcoma (PD-PPSS) is a rare, aggressive neoplasm, which occurs in 0.5% cases of all lung malignancies. The diagnosis of PD-PPSS can be very challenging on cytology samples. We present here an unusual case of PD-PPSS diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), in the setting of known history of diffuse large B-cell lymphoma. Diff-Quik and Papanicolaou stains showed cellular specimen with clusters of highly atypical small round blue cells admixed with lymphoid elements; and some with denuded cytoplasm...
August 18, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28832765/is-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-with-a-stylet-necessary-for-lymph-node-screening-in-lung-cancer-patients
#19
Y Xu, J Lin, Y Jin, X Wu, H Zheng, J Feng
During endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), a needle is commonly used with a stylet, although recently the stylet has been omitted. This prospective study aimed to compare the quality of specimens obtained by EBUS-TBNA performed with and without a stylet. Between November 2013 and November 2014, 131 patients with lung cancer underwent EBUS-TBNA, with a total of 148 mediastinal or hilar lymph nodes sampled both with and without an inner-stylet, yielding 296 cytological specimens...
August 17, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28819382/effectiveness-of-the-benign-and-malignant-diagnosis-of-mediastinal-and-hilar-lymph-nodes-by-endobronchial-ultrasound-elastography
#20
Haidong Huang, Zhiang Huang, Qin Wang, Xinan Wang, Yuchao Dong, Wei Zhang, Paul Zarogoulidis, Yan-Gao Man, Wolfgang Hohenforst Schmidt, Chong Bai
Background and Objectives: Endobronchial ultrasound elastography is a new technique for describing the stiffness of tissue during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The aims of this study were to investigate the diagnostic value of Endobronchial ultrasound (EBUS) elastography for distinguishing the difference between benign and malignant lymph nodes among mediastinal and hilar lymph node. Materials and Methods: From June 2015 to August 2015, 47 patients confirmed of mediastinal and hilar lymph node enlargement through examination of Computed tomography (CT) were enrolled, and a total of 78 lymph nodes were evaluated by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)...
2017: Journal of Cancer
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