keyword
https://read.qxmd.com/read/38646394/comparative-evaluation-of-linscope-and-king-vision-video-laryngoscopes-in-tracheal-intubation-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Mohd Luqman, S Moied Ahmed, Amal Shaharyar, Raihan Mannan
Introduction Indirect laryngoscopy has become a widely accepted method for learning the techniques of airway management. The incorporation of small, less expensive, and yet more reliable video cameras in laryngoscopes has given the process of laryngoscopy and intubation a big leap. The King Vision video laryngoscope (Medline Industries, USA) has demonstrated promise in several settings while the Linscope video laryngoscope (Centrum, Turkey) is a newly launched device and no literature is available to the best of our knowledge...
March 2024: Curēus
https://read.qxmd.com/read/38582675/the-incidence-and-patterns-of-maxillofacial-fractures-and-associated-head-and-neck-injuries
#2
JOURNAL ARTICLE
Anwar B Bataineh
The aim of this study was to evaluate the incidence and patterns of maxillofacial fractures and the demographic characteristics of associated head and neck injuries. This single-center retrospective cohort study was conducted at the Department of Oral and Maxillofacial Surgery of King Abdullah University Hospital (KAUH) in Irbid, northern Jordan. The data was obtained from the electronic clinical records of all patients in whom maxillofacial fractures and associated head and neck injuries were confirmed. During the five-year period captured by this retrospective study, 481 patients with 1026 maxillofacial fractures (equivalent to 2...
March 18, 2024: Journal of Cranio-maxillo-facial Surgery
https://read.qxmd.com/read/38564008/factors-affecting-graft-healing-in-laryngotracheal-reconstruction-a-retrospective-single-center-experience
#3
JOURNAL ARTICLE
Abdullah Sindi, Fatima S Alangari, Yara Akkielah, Nasser Almutairi, Abdulah Aljasser, Ahmed Alammar
PURPOSE: To examine the factors that affect graft healing after laryngotracheal reconstruction (LTR). METHODS: We conducted a retrospective chart review at King Abdulaziz University Hospital, Riyadh, Saudi Arabia, between January-2008 and October-2023. We included all patients who underwent LTR and required anterior and/or posterior graft placement, while those who underwent procedures without graft placement and those with incomplete information were excluded. RESULTS: Forty-nine patients were analyzed...
April 2, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38544576/improving-asthma-outcomes-clinicians-perspectives-on-peripheral-airways
#4
JOURNAL ARTICLE
Gregory G King, Li Ping Chung, Omar S Usmani, Kris Nilsen, Bruce R Thompson
Disease of the peripheral (or small) airways is fundamental in asthma, being closely related to symptoms (or lack of control of them), airway hyperresponsiveness, spirometric abnormalities, risk of loss of control, or exacerbations and inflammation. Current technology now allows routine measurement of peripheral airway function. Having a working concept of peripheral airways disease in asthma is arguably very useful to clinicians and beneficial to patients because it allows a more comprehensive assessment of asthma severity (rather than just symptoms alone, which is the norm), tracking of progress or deterioration, and assessing response to treatment...
May 2024: J Allergy Clin Immunol Glob
https://read.qxmd.com/read/38482576/chemoradiation-to-the-submental-muscles-alters-hyoid-movement-during-swallowing-in-a-rat-model
#5
JOURNAL ARTICLE
Suzanne N King, Abigail Kuntz, Nathan Scott, Brittany Smiley, Andres Portocarrero Bonifaz, Megan Blackburn
Hyolaryngeal dysfunction is a commonly reported swallowing problem after chemoradiation treatment for head and neck cancer. The displacement of the hyolaryngeal complex during swallowing protects the airway and assists in opening the upper esophageal sphincter. Activation of the submental muscles, specifically the mylohyoid and geniohyoid muscles, are thought to facilitate movement of the hyoid. The purpose of this study was to determine if targeted radiation to the submental muscles given concurrently with chemotherapy alters hyolaryngeal displacement one-month after treatment...
March 14, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38470489/natural-antibodies-drive-type-2-immunity-in-response-to-damage-associated-molecular-patterns
#6
JOURNAL ARTICLE
Arlind B Mara, Kavita Rawat, William T King, Claudia V Jakubzick
Allergic Airway Disease (AAD) is an example of type 2 inflammation which leads to chronic airway eosinophilia controlled by CD4 Th2 cells. Inflammation is reinforced by mast cells and basophils armed with allergen-specific IgE made by allergen-specific B2 B cells of the adaptive immune system. Little is known about how AAD is affected by innate B1 cells which produce natural antibodies (NAbs) that facilitate apoptotic cell clearance and detect damage and pathogen associated molecular patterns (DAMPS and PAMPS)...
March 12, 2024: JCI Insight
https://read.qxmd.com/read/38343674/comparison-of-intubating-conditions-in-supine-sniffing-and-25%C3%A2-back-up-position-using-channelled-and-non-channelled-video-laryngoscopes-a-randomised-controlled-study
#7
JOURNAL ARTICLE
Devyani Desai, Riddhi Sompura, Sudarshan Yadav
BACKGROUND AND AIMS: The 25°back-up position is proposed to increase the efficacy of preoxygenation and provide better tracheal intubating conditions when using a direct laryngoscope. This study aimed to compare the ease of tracheal intubation between supine and 25° back-up positions when using two video laryngoscopes (VLS). METHODS: One hundred adults with normal airways and belonging to the American Society of Anesthesiologists physical status classes I and II, requiring general anaesthesia, were randomised in groups K and M...
December 2023: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38331563/faecal-microbial-transfer-and-complex-carbohydrates-mediate-protection-against-copd
#8
JOURNAL ARTICLE
Kurtis F Budden, Shakti D Shukla, Kate L Bowerman, Annalicia Vaughan, Shaan L Gellatly, David L A Wood, Nancy Lachner, Sobia Idrees, Saima Firdous Rehman, Alen Faiz, Vyoma K Patel, Chantal Donovan, Charlotte A Alemao, Sj Shen, Nadia Amorim, Rajib Majumder, Kanth S Vanka, Jazz Mason, Tatt Jhong Haw, Bree Tillet, Michael Fricker, Simon Keely, Nicole Hansbro, Gabrielle T Belz, Jay Horvat, Thomas Ashhurst, Caryn van Vreden, Helen McGuire, Barbara Fazekas de St Groth, Nicholas J C King, Ben Crossett, Stuart J Cordwell, Lorenzo Bonaguro, Joachim L Schultze, Emma E Hamilton-Williams, Elizabeth Mann, Samuel C Forster, Matthew A Cooper, Leopoldo N Segal, Sanjay H Chotirmall, Peter Collins, Rayleen Bowman, Kwun M Fong, Ian A Yang, Peter A B Wark, Paul G Dennis, Philip Hugenholtz, Philip M Hansbro
OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is a major cause of global illness and death, most commonly caused by cigarette smoke. The mechanisms of pathogenesis remain poorly understood, limiting the development of effective therapies. The gastrointestinal microbiome has been implicated in chronic lung diseases via the gut-lung axis, but its role is unclear. DESIGN: Using an in vivo mouse model of cigarette smoke (CS)-induced COPD and faecal microbial transfer (FMT), we characterised the faecal microbiota using metagenomics, proteomics and metabolomics...
February 8, 2024: Gut
https://read.qxmd.com/read/38175484/perceived-benefits-of-bariatric-surgery-patient-perspectives
#9
JOURNAL ARTICLE
Moath S Alsaqaaby, Khaled A Alabduljabbar, Heshma R Alruwaili, Karl J Neff, Helen M Heneghan, Dimitri J Pournaras, Carel W Le Roux
BACKGROUND: Obesity is a chronic and complex disease characterized by the excessive accumulation of adipose tissue, which has detrimental effects on health. Evaluating the changes in quality of life (QoL) after bariatric surgery complements the medical benefits which are documented by healthcare professionals. PURPOSE: To study the perceived health benefits 1 year after substantial weight loss induced by bariatric surgery. METHODS: This pilot study evaluated patients 1 year after bariatric surgery using 13 questions related to the health domains of the KOSS: airway, body mass, cardiovascular risk, diabetes, economic impact, functional, gonadal impact, health status perceived, image, junction of the gastro-esophagus, kidney, liver, and medication...
January 4, 2024: Obesity Surgery
https://read.qxmd.com/read/38164864/lung-functions-pre-and-post-endoscopic-balloon-dilation-treatment-among-patients-with-subglottic-stenosis
#10
JOURNAL ARTICLE
S A Meo, I M U Meo, F Al-Rouq, T Al-Khlaiwi, S F Aldhahri, M S Almahmoud
OBJECTIVE: Subglottic stenosis (SGS) is an unusual clinical condition of mucosal wounding, compromising the extra-thoracic part of the tracheal airway below the vocal folds. The diagnosis of SGS is established with a detailed clinical examination and a direct endoscopic examination, and the role of spirometry is also often acknowledged. This study aimed to investigate the impact of SGS on lung functions before and after the balloon dilation procedure. PATIENTS AND METHODS: The respiratory functions were performed in the Department of Clinical Physiology and the Department of Otolaryngology College of Medicine, King Saud University, Riyadh, Saudi Arabia...
December 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38141851/evaluation-of-high-dose-n-acetylcysteine-on-airway-inflammation-and-quality-of-life-outcomes-in-adults-with-bronchiectasis-a-randomised-placebo-controlled-pilot-study
#11
RANDOMIZED CONTROLLED TRIAL
L Jayaram, P T King, J Hunt, M Lim, C Park, E Hu, L Dousha, P Ha, J B Bartlett, A M Southcott, S Muruganandan, S Vogrin, M A Rees, O M Dean, C A Wong
BACKGROUND: High dose N acetylcysteine (NAC), a mucolytic, anti-inflammatory and antioxidant agent has been shown to significantly reduce exacerbations, and improve quality of life in placebo controlled, double blind randomised (RCT) studies in patients with COPD, and in an open, randomised study in bronchiectasis. In this pilot, randomised, double-blind, placebo-controlled study, we wished to investigate the feasibility of a larger clinical trial, and the anti-inflammatory and clinical benefits of high dose NAC in bronchiectasis...
March 2024: Pulmonary Pharmacology & Therapeutics
https://read.qxmd.com/read/38086256/management-and-outcomes-of-patients-with-high-risk-congenital-lung-malformation-volume-ratio%C3%A2-1-6-congenital-lung-malformations
#12
JOURNAL ARTICLE
Ashley Montgomery, Sarah Peiffer, Steven Mehl, Timothy C Lee, Sundeep G Keswani, Alice King
INTRODUCTION: Congenital lung malformations (CLMs) have a variable natural history. Larger lesions with CLM volume ratio (CVR) ≥ 1.6 are associated with hydrops and fetal mortality. The purpose of this study is to describe the management and outcomes of high-risk (CVR ≥ 1.6) CLM patients. METHODS: A retrospective cohort study was performed for all fetuses evaluated between May 2015 and May 2022. Demographics, prenatal imaging factors, prenatal and postnatal treatment, and outcomes were collected...
December 11, 2023: Journal of Surgical Research
https://read.qxmd.com/read/38022228/disease-outcomes-of-covid-19-in-diabetic-and-hypertensive-patients-during-the-hospital-stay
#13
JOURNAL ARTICLE
Amina Abid, Arooj Umar, Samina Qamar
Background A single-stranded RNA genome-encapsulated virus known as severe acute respiratory syndrome coronavirus 2 is known to cause severe acute respiratory syndrome in humans. People with diabetes and hypertension are often more susceptible to developing coronavirus disease 2019 (COVID-19) and experience a disproportionately higher rate of morbidity and death compared to the general population. The COVID-19 pandemic has become an urgent worldwide issue. Therefore, the main goal of this study is to assess how diabetes and hypertension, both separately and together, affect clinical outcomes in terms of morbidity and mortality in patients hospitalized with COVID-19...
October 2023: Curēus
https://read.qxmd.com/read/38022114/morpho-volumetric-changes-of-the-pharyngeal-airway-with-traumatic-maxillofacial-injuries-a-retrospective-radiographic-study
#14
JOURNAL ARTICLE
Muath S Alassaf, Hamza K Khan, Osama A Habib, Ayyob E Aboalkhair, Hasan A Albeshir, Mahmood M Samman
BACKGROUND: When dealing with traumatized patients, it is crucial to prioritize securing their airway. However, intubating someone who has sustained significant facial injuries can pose difficulties, as the narrow and altered shape of their upper airway may impede their ability to open their mouth. In light of this, the purpose of this study is to evaluate the volumetric and morphological alterations to the upper airway resulting from facial trauma by utilizing computed tomography (CT) scans...
October 2023: Curēus
https://read.qxmd.com/read/37802486/adult-perioperative-cardiac-arrest-an-overview-of-684-cases-reported-to-webairs
#15
JOURNAL ARTICLE
Matthew R Bright, Yasmin Endlich, Zachary Dj King, Leigh D White, Sandra I Concha Blamey, Martin D Culwick
There were 684 perioperative cardiac arrests reported to webAIRS between September 2009 and March 2022. The majority involved patients older than 60 years, classified as American Society of Anesthesiologists Physical Status 3 to 5, undergoing an emergency or major procedure. The most common precipitants included airway events, cardiovascular events, massive blood loss. medication issues, and sepsis. The highest mortality rate was 54% of the 46 cases in the miscellaneous category (this included 34 cases of severe sepsis, which had a mortality of 65%)...
November 2023: Anaesthesia and Intensive Care
https://read.qxmd.com/read/37721483/plasma-metanephrines-yield-fewer-false-positive-results-than-urine-metanephrines-in-obstructive-sleep-apnea-patients
#16
JOURNAL ARTICLE
Thomas F J King, Yingjuan Mok, Lily Mae Dacay, Hang Siang Wong, Pon Poh Hsu, Alvin Tan, Kang Min Wong, Ehsan Saffari Seyed, Jacques W M Lenders, Troy H Puar
INTRODUCTION: Obstructive sleep apnea (OSA) is associated with increased nocturnal sympathetic activity. In OSA patients, elevations in metanephrines may lead to false positive tests when evaluating for pheochromocytoma or paraganglioma (PPGL). We hypothesized that morning plasma metanephrines would lead to fewer false-positive results than 24-hour urinary metanephrines in OSA patients. METHODS: Patients undergoing polysomnography for suspected OSA were recruited...
September 18, 2023: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/37708638/home-high-flow-nasal-therapy-in-a-patient-with-pleuroparenchymal-fibroelastosis-a-case-report
#17
Kazuhiko Iwasaki, Satoshi Watanabe, Akihito Okazaki, Seiji Yano
A 62-year-old man with pleuroparenchymal fibroelastosis (PPFE), who had been under observation for 19 years, was admitted due to headache, fatigue, and dyspnea. Although no acute findings were detected, his symptoms were attributed to hypercapnia and exertional hypoxemia. He had a history of pneumothorax, but chose not to undergo positive airway pressure ventilation. Consequently, home high-flow nasal therapy (HFNT) was initiated, and 4 months later, he observed an improvement in his quality of life, body weight gain, and relief from hypercapnia...
September 12, 2023: Respiratory Investigation
https://read.qxmd.com/read/37654667/domiciliary-transcutaneous-electrical-stimulation-in-patients-with-obstructive-sleep-apnoea-and-limited-adherence-to-continuous-positive-airway-pressure-therapy-a-single-centre-open-label-randomised-controlled-phase-iii-trial
#18
JOURNAL ARTICLE
Deeban Ratneswaran, Michael Cheng, Ebrahim Nasser, Rajiv Madula, Martino Pengo, Kath Hope, Esther I Schwarz, Yuanming Luo, Georgios Kaltsakas, Michael I Polkey, John Moxham, Joerg Steier
BACKGROUND: Hypoglossal nerve stimulation (HNS) for obstructive sleep apnoea (OSA) is a novel way to manage the condition. We hypothesised that in patients with OSA and limited adherence to continuous positive airway pressure (CPAP) therapy, domiciliary transcutaneous electrical stimulation (TESLA) would control sleep apnoea and provide health benefits. METHODS: We undertook a single-centre, open-label, randomised, controlled phase III trial in patients with OSA (apnoea-hypopnoea-index [AHI] 5-35 h-1 ), a BMI of 18...
August 2023: EClinicalMedicine
https://read.qxmd.com/read/37636724/efficacy-of-cricotracheal-stenosis-resection-ctsr-among-children-with-congenital-vs-acquired-sub-glottic-stenosis
#19
JOURNAL ARTICLE
Jaber Alshammari, Mohammed Halawani, Abdullah Arafat, Abdullah Alkhaldi, Nazish Masud
Sub-glottic Stenosis (SGS) treatment in children is challenging because there is no standard algorithm to follow; however, the use of endoscopic techniques in SGS treatment has emerged over the last decades and has advanced. The aim of this study was to assess the efficacy of Cricotracheal Stenosis Resection (CTSR) among children with congenital vs. acquired SGS. In this retrospective study, we reviewed the charts of 22 patients who underwent endoscopic intervention as the primary modality of treatment for SGS at King Abdulaziz Medical City from January 1, 2011 to October 31, 2019...
September 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37615417/right-place-no-trace-a-case-report-of-postintubation-bronchospasm
#20
JOURNAL ARTICLE
James P King, Nagendra K Natarajan
Evidence suggests obesity correlates with airway hyperreactivity, which can result in severe bronchospasm. This report presents a 31-year-old female with a high body mass index who presented for a laparoscopic hysterectomy and bilateral salpingo-oophorectomy. She had no past medical or atopic history. After induction of anaesthesia and intubation, O2 saturation fell with no CO2 trace, breathing sounds or chest rise. Despite confirming endotracheal tube position by video laryngoscopy, the CO2 trace remained flat and mechanical ventilation was difficult with high airway pressures...
August 24, 2023: Journal of Perioperative Practice
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