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https://www.readbyqxmd.com/read/29310711/impact-of-collaborative-pharmaceutical-care-on-in-patients-medication-safety-study-protocol-for-a-stepped-wedge-cluster-randomized-trial-medrev-study
#1
Géraldine Leguelinel-Blache, Christel Castelli, Clarisse Roux-Marson, Sophie Bouvet, Sandrine Andrieu, Philippe Cestac, Rémy Collomp, Paul Landais, Bertrice Loulière, Christelle Mouchoux, Rémi Varin, Benoit Allenet, Pierrick Bedouch, Jean-Marie Kinowski
BACKGROUND: Clinical pharmaceutical care has long played an important role in the improvement of healthcare safety. Pharmaceutical care is a collaborative care approach, implicating all the actors of the medication circuit in order to prevent and correct drug-related problems that can lead to adverse drug events. The collaborative pharmaceutical care performed during patients' hospitalization requires two mutually reinforcing activities: medication reconciliation and medication review...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29242497/silicon-cmos-architecture-for-a-spin-based-quantum-computer
#2
M Veldhorst, H G J Eenink, C H Yang, A S Dzurak
Recent advances in quantum error correction codes for fault-tolerant quantum computing and physical realizations of high-fidelity qubits in multiple platforms give promise for the construction of a quantum computer based on millions of interacting qubits. However, the classical-quantum interface remains a nascent field of exploration. Here, we propose an architecture for a silicon-based quantum computer processor based on complementary metal-oxide-semiconductor (CMOS) technology. We show how a transistor-based control circuit together with charge-storage electrodes can be used to operate a dense and scalable two-dimensional qubit system...
December 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/29220983/biomimetic-spiral-grating-for-stable-and-highly-efficient-absorption-in-crystalline-silicon-thin-film-solar-cells-erratum
#3
Jin Hou, Wei Hong, Xiaohang Li, Chunyong Yang, Shaoping Chen
In the original manuscript, the maximum short-circuit current in Fig. 2 and the description of angular stability for polarization in Fig. 6 are found incorrect owing to negligence. The incorrect maximum integrated absorption also led to errors appeared in Fig. 3 and Fig. 4(d), in which the mistake value was used to plot. In this erratum, all of those mistakes have been corrected. Moreover, both higher Fourier expansion order and the resolution of frequency are adopted in the recalculation to make sure the updated results to be reliable...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29213234/cognitive-mapping-based-on-conjunctive-representations-of-space-and-movement
#4
Taiping Zeng, Bailu Si
It is a challenge to build robust simultaneous localization and mapping (SLAM) system in dynamical large-scale environments. Inspired by recent findings in the entorhinal-hippocampal neuronal circuits, we propose a cognitive mapping model that includes continuous attractor networks of head-direction cells and conjunctive grid cells to integrate velocity information by conjunctive encodings of space and movement. Visual inputs from the local view cells in the model provide feedback cues to correct drifting errors of the attractors caused by the noisy velocity inputs...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/29094787/functional-dysconnectivity-of-the-limbic-loop-of-frontostriatal-circuits-in-first-episode-treatment-naive-schizophrenia
#5
Pan Lin, Xiaosheng Wang, Bei Zhang, Brian Kirkpatrick, Dost Öngür, James J Levitt, Jorge Jovicich, Shuqiao Yao, Xiang Wang
Frontostriatal circuits dysfunction has been implicated in the etiology and psychopathology of patients with schizophrenia (SZ). However, few studies have investigated SZ-related functional connectivity (FC) alterations in discrete frontostriatal circuits and their relationship with pathopsychology in first-episode schizophrenia (FESZ). The goal of this study was to identify dysfunctions in discrete frontostriatal circuits that are associated with key features of FESZ. To this end, a case-control, cross-sectional study was conducted, wherein resting-state (RS) functional magnetic resonance (fMRI) data were collected from 37 treatment-naïve FESZ patients and 29 healthy control (HC) subjects...
November 2, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28949639/degeneracy-preserving-quantum-nondemolition-measurement-of-parity-type-observables-for-cat-qubits
#6
Joachim Cohen, W Clarke Smith, Michel H Devoret, Mazyar Mirrahimi
A central requirement for any quantum error correction scheme is the ability to perform quantum nondemolition measurements of an error syndrome, corresponding to a special symmetry property of the encoding scheme. It is in particular important that such a measurement does not introduce extra error mechanisms, not included in the error model of the correction scheme. In this Letter, we ensure such a robustness by designing an interaction with a measurement device that preserves the degeneracy of the measured observable...
August 11, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28947008/a-method-for-generating-3d-thermal-models-with-decoupled-acquisition
#7
Andriy Guilherme Krefer, Maiko Min Ian Lie, Gustavo Benvenutti Borba, Humberto Remigio Gamba, Marcos Dinís Lavarda, Mauren Abreu de Souza
BACKGROUND AND OBJECTIVE: Both thermal imaging and 3D scanning offer convenient advantages for medical applications, namely, being contactless, non-invasive and fast. Consequently, many approaches have been proposed to combine both sensing modalities in order to acquire 3D thermal models. The predominant approach is to affix a 3D scanner and a thermal camera in the same support and calibrate them together. While this approach allows straightforward projection of thermal images over the 3D mesh, it requires their simultaneous acquisition...
November 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28874706/synthesis-of-arbitrary-quantum-circuits-to-topological-assembly-systematic-online-and-compact
#8
Alexandru Paler, Austin G Fowler, Robert Wille
It is challenging to transform an arbitrary quantum circuit into a form protected by surface code quantum error correcting codes (a variant of topological quantum error correction), especially if the goal is to minimise overhead. One of the issues is the efficient placement of magic state distillation sub circuits, so-called distillation boxes, in the space-time volume that abstracts the computation's required resources. This work presents a general, systematic, online method for the synthesis of such circuits...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28820602/intricate-resonant-raman-response-in-anisotropic-res2
#9
Amber McCreary, Jeffrey R Simpson, Yuanxi Wang, Daniel Rhodes, Kazunori Fujisawa, Luis Balicas, Madan Dubey, Vincent H Crespi, Mauricio Terrones, Angela R Hight Walker
The strong in-plane anisotropy of rhenium disulfide (ReS2) offers an additional physical parameter that can be tuned for advanced applications such as logic circuits, thin-film polarizers, and polarization-sensitive photodetectors. ReS2 also presents advantages for optoelectronics, as it is both a direct-gap semiconductor for few-layer thicknesses (unlike MoS2 or WS2) and stable in air (unlike black phosphorus). Raman spectroscopy is one of the most powerful characterization techniques to nondestructively and sensitively probe the fundamental photophysics of a 2D material...
October 11, 2017: Nano Letters
https://www.readbyqxmd.com/read/28609480/an-automated-and-reliable-method-for-breath-detection-during-variable-mask-pressures-in-awake-and-sleeping-humans
#10
Chinh D Nguyen, Jason Amatoury, Jayne C Carberry, Danny J Eckert
Accurate breath detection is crucial in sleep and respiratory physiology research and in several clinical settings. However, this process is technically challenging due to measurement and physiological artifacts and other factors such as variable leaks in the breathing circuit. Recently developed techniques to quantify the multiple causes of obstructive sleep apnea, require intermittent changes in airway pressure applied to a breathing mask. This presents an additional unique challenge for breath detection...
2017: PloS One
https://www.readbyqxmd.com/read/28573311/kinematics-in-the-brain-unmasking-motor-control-strategies
#11
Liesjet E H Van Dokkum, D Mottet, I Laffont, A Bonafé, N Menjot de Champfleur, J Froger, E Le Bars
In rhythmical movement performance, our brain has to sustain movement while correcting for biological noise-induced variability. Here, we explored the functional anatomy of brain networks during voluntary rhythmical elbow flexion/extension using kinematic movement regressors in fMRI analysis to verify the interest of method to address motor control in a neurological population. We found the expected systematic activation of the primary sensorimotor network that is suggested to generate the rhythmical movement...
June 2, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28553479/a-dna-based-parity-generator-checker-for-error-detection-through-data-transmission-with-visual-readout-and-an-output-correction-function
#12
Daoqing Fan, Erkang Wang, Shaojun Dong
During any type of binary data transmission, the occurrence of bit errors is an inevitable and frequent problem suffered. These errors, which have fatal effects on the correct logic computation, especially in sophisticated logic circuits, can be checked through insertion of a parity generator (pG) at the transmitting end and a parity checker (pC) at the receiving end. Herein, taking even pG/pC as a model device, we constructed the first DNA-based molecular parity generator/checker (pG/pC) for error detection through data transmission, on a universal single-strand platform according to solely DNA hybridization...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28409953/quantum-state-transfer-via-noisy-photonic-and-phononic-waveguides
#13
B Vermersch, P-O Guimond, H Pichler, P Zoller
We describe a quantum state transfer protocol, where a quantum state of photons stored in a first cavity can be faithfully transferred to a second distant cavity via an infinite 1D waveguide, while being immune to arbitrary noise (e.g., thermal noise) injected into the waveguide. We extend the model and protocol to a cavity QED setup, where atomic ensembles, or single atoms representing quantum memory, are coupled to a cavity mode. We present a detailed study of sensitivity to imperfections, and apply a quantum error correction protocol to account for random losses (or additions) of photons in the waveguide...
March 31, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28375210/corticolimbic-hyper-response-to-emotion-and-glutamatergic-function-in-people-with-high-schizotypy-a-multimodal-fmri-mrs-study
#14
G Modinos, A McLaughlin, A Egerton, K McMullen, V Kumari, G J Barker, C Keysers, S C R Williams
Animal models and human neuroimaging studies suggest that altered levels of glutamatergic metabolites within a corticolimbic circuit have a major role in the pathophysiology of schizophrenia. Rodent models propose that prefrontal glutamate dysfunction could lead to amygdala hyper-response to environmental stress and underlie hippocampal overdrive in schizophrenia. Here we determine whether changes in brain glutamate are present in individuals with high schizotypy (HS), which refers to the presence of schizophrenia-like characteristics in healthy individuals, and whether glutamate levels are related to altered corticolimbic response to emotion...
April 4, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28374674/rules-and-mechanisms-for-efficient-two-stage-learning-in-neural-circuits
#15
Tiberiu Teşileanu, Bence Ölveczky, Vijay Balasubramanian
Trial-and-error learning requires evaluating variable actions and reinforcing successful variants. In songbirds, vocal exploration is induced by LMAN, the output of a basal ganglia-related circuit that also contributes a corrective bias to the vocal output. This bias is gradually consolidated in RA, a motor cortex analogue downstream of LMAN. We develop a new model of such two-stage learning. Using stochastic gradient descent, we derive how the activity in 'tutor' circuits (e.g., LMAN) should match plasticity mechanisms in 'student' circuits (e...
April 4, 2017: ELife
https://www.readbyqxmd.com/read/28368355/a-reconfigurable-readout-integrated-circuit-for-heterogeneous-display-based-multi-sensor-systems
#16
Kyeonghwan Park, Seung Mok Kim, Won-Jin Eom, Jae Joon Kim
This paper presents a reconfigurable multi-sensor interface and its readout integrated circuit (ROIC) for display-based multi-sensor systems, which builds up multi-sensor functions by utilizing touch screen panels. In addition to inherent touch detection, physiological and environmental sensor interfaces are incorporated. The reconfigurable feature is effectively implemented by proposing two basis readout topologies of amplifier-based and oscillator-based circuits. For noise-immune design against various noises from inherent human-touch operations, an alternate-sampling error-correction scheme is proposed and integrated inside the ROIC, achieving a 12-bit resolution of successive approximation register (SAR) of analog-to-digital conversion without additional calibrations...
April 3, 2017: Sensors
https://www.readbyqxmd.com/read/28361950/implementation-of-a-quantum-controlled-swap-gate-with-photonic-circuits
#17
Takafumi Ono, Ryo Okamoto, Masato Tanida, Holger F Hofmann, Shigeki Takeuchi
Quantum information science addresses how the processing and transmission of information are affected by uniquely quantum mechanical phenomena. Combination of two-qubit gates has been used to realize quantum circuits, however, scalability is becoming a critical problem. The use of three-qubit gates may simplify the structure of quantum circuits dramatically. Among them, the controlled-SWAP (Fredkin) gates are essential since they can be directly applied to important protocols, e.g., error correction, fingerprinting, and optimal cloning...
March 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28231527/rapid-discrimination-and-determination-of-antibiotics-drugs-in-plastic-syringes-using-near-infrared-spectroscopy-with-chemometric-analysis-application-to-amoxicillin-and-penicillin
#18
Laetitia Minh Mai Lê, Luc Eveleigh, Ikram Hasnaoui, Patrice Prognon, Arlette Baillet-Guffroy, Eric Caudron
The aim of this study was to investigate near infrared spectroscopy (NIRS) combined to chemometric analysis to discriminate and quantify three antibiotics by direct measurement in plastic syringes.Solutions of benzylpenicillin (PENI), amoxicillin (AMOX) and amoxicillin/clavulanic acid (AMOX/CLAV) were analyzed at therapeutic concentrations in glass vials and plastic syringes with NIR spectrometer by direct measurement. Chemometric analysis using partial least squares regression and discriminative analysis was conducted to develop qualitative and quantitative calibration models...
May 10, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28218673/a-high-performance-piezoelectric-sensor-for-dynamic-force-monitoring-of-landslide
#19
Ming Li, Wei Cheng, Jiangpan Chen, Ruili Xie, Xiongfei Li
Due to the increasing influence of human engineering activities, it is important to monitor the transient disturbance during the evolution process of landslide. For this purpose, a high-performance piezoelectric sensor is presented in this paper. To adapt the high static and dynamic stress environment in slope engineering, two key techniques, namely, the self-structure pressure distribution method (SSPDM) and the capacitive circuit voltage distribution method (CCVDM) are employed in the design of the sensor...
February 17, 2017: Sensors
https://www.readbyqxmd.com/read/28196412/mapk3-at-the-autism-linked-human-16p11-2-locus-influences-precise-synaptic-target-selection-at-drosophila-larval-neuromuscular-junctions
#20
Sang Mee Park, Hae Ryoun Park, Ji Hye Lee
Proper synaptic function in neural circuits requires precise pairings between correct pre- and post-synaptic partners. Errors in this process may underlie development of neuropsychiatric disorders, such as autism spectrum disorder (ASD). Development of ASD can be influenced by genetic factors, including copy number variations (CNVs). In this study, we focused on a CNV occurring at the 16p11.2 locus in the human genome and investigated potential defects in synaptic connectivity caused by reduced activities of genes located in this region at Drosophila larval neuromuscular junctions, a well-established model synapse with stereotypic synaptic structures...
February 2017: Molecules and Cells
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