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https://www.readbyqxmd.com/read/29722352/epilepsy
#1
REVIEW
Orrin Devinsky, Annamaria Vezzani, Terence J O'Brien, Nathalie Jette, Ingrid E Scheffer, Marco de Curtis, Piero Perucca
Epilepsy affects all age groups and is one of the most common and most disabling neurological disorders. The accurate diagnosis of seizures is essential as some patients will be misdiagnosed with epilepsy, whereas others will receive an incorrect diagnosis. Indeed, errors in diagnosis are common, and many patients fail to receive the correct treatment, which often has severe consequences. Although many patients have seizure control using a single medication, others require multiple medications, resective surgery, neuromodulation devices or dietary therapies...
May 3, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29674654/author-correction-circuit-dissection-of-the-role-of-somatostatin-in-itch-and-pain
#2
Jing Huang, Erika Polgár, Hans Jürgen Solinski, Santosh K Mishra, Pang-Yen Tseng, Noboru Iwagaki, Kieran A Boyle, Allen C Dickie, Mette C Kriegbaum, Hendrik Wildner, Hanns Ulrich Zeilhofer, Masahiko Watanabe, John S Riddell, Andrew J Todd, Mark A Hoon
In the version of this article initially published online, the labels were switched for the right-hand pair of bars in Fig. 4e. The left one of the two should be Chloroquine + veh, the right one Chloroquine + CNO. The error has been corrected in the print, HTML and PDF versions of the article.
April 19, 2018: Nature Neuroscience
https://www.readbyqxmd.com/read/29549316/publisher-correction-a-craniofacial-specific-monosynaptic-circuit-enables-heightened-affective-pain
#3
Erica Rodriguez, Katsuyasu Sakurai, Jennie Xu, Yong Chen, Koji Toda, Shengli Zhao, Bao-Xia Han, David Ryu, Henry Yin, Wolfgang Liedtke, Fan Wang
In the version of this article initially published, ORCID links were missing for authors Erica Rodriguez, Koji Toda and Fan Wang. The error has been corrected in the HTML and PDF versions of the article.
March 16, 2018: Nature Neuroscience
https://www.readbyqxmd.com/read/29515215/publisher-correction-medial-preoptic-circuit-induces-hunting-like-actions-to-target-objects-and-prey
#4
Sae-Geun Park, Yong-Cheol Jeong, Dae-Gun Kim, Min-Hyung Lee, Anna Shin, Geunhong Park, Jia Ryoo, Jiso Hong, Seohui Bae, Cheol-Hu Kim, Phill-Seung Lee, Daesoo Kim
In the version of this article initially published, a sentence in the fifth paragraph of the Results read, "Immunohistochemistry revealed that VGLUT2+ MPA neurons rarely expressed CaMKIIα, which is a putative marker for subcortical glutamatergic neurons." It should have read, "Immunohistochemistry revealed that CaMKIIα+ MPA neurons rarely expressed VGLUT2, which is a putative marker for subcortical glutamatergic neurons." The error has been corrected in the HTML and PDF versions of the article...
March 7, 2018: Nature Neuroscience
https://www.readbyqxmd.com/read/29487038/a-flow-leak-correction-algorithm-for-pneumotachographic-work-of-breathing-measurement-during-high-flow-nasal-cannula-oxygen-therapy
#5
Francesco Montecchia, Fabio Midulla, Paola Papoff
Measuring work of breathing (WOB) is an intricate task during high-flow nasal cannula (HFNC) therapy because the continuous unidirectional flow toward the patient makes pneumotachography technically difficult to use. We implemented a new method for measuring WOB based on a differential pneumotachography (DP) system, equipped with one pneumotachograph inserted in the HFNC circuit and another connected to a monitoring facemask, combined with a leak correction algorithm (LCA) that corrects flow measurement errors arising from leakage around the monitoring facemask...
April 2018: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29428618/robustness-of-expression-pattern-formation-due-to-dynamic-equilibrium-in-gap-gene-system-of-an-early-drosophila-embryo
#6
Ekaterina Myasnikova, Alexander Spirov
The first manifestation of a segmentation pattern in the early Drosophila development is the formation of expression domains of genes belonging to the gap class. In our previous research the phenomenon of the gap system's robustness, exhibited as the ability to reduce highly variable gene expression in the course of development, was explained as a result of gene cross-regulation. In this paper we formulate the rigorous robustness conditions using the inherent properties of gap gene family. We propose an approach based on the observation that for the formation of a pattern with well-established domain borders it is necessary that there exist a stationary nucleus in which the gene expression level is almost constant in time...
April 2018: Bio Systems
https://www.readbyqxmd.com/read/29422549/author-correction-midbrain-circuit-regulation-of-individual-alcohol-drinking-behaviors-in-mice
#7
Barbara Juarez, Carole Morel, Stacy M Ku, Yutong Liu, Hongxing Zhang, Sarah Montgomery, Hilledna Gregoire, Efrain Ribeiro, Marshall Crumiller, Ciorana Roman-Ortiz, Jessica J Walsh, Kelcy Jackson, Denise E Croote, Yingbo Zhu, Song Zhang, Leandro F Vendruscolo, Scott Edwards, Amanda Roberts, Georgia E Hodes, Yongke Lu, Erin S Calipari, Dipesh Chaudhury, Allyson K Friedman, Ming-Hu Han
The original version of this Article contained an error in the spelling of the author Scott Edwards, which was incorrectly given as Scott Edward. This has now been corrected in both the PDF and HTML versions of the Article.
February 8, 2018: Nature Communications
https://www.readbyqxmd.com/read/29310711/impact-of-collaborative-pharmaceutical-care-on-in-patients-medication-safety-study-protocol-for-a-stepped-wedge-cluster-randomized-trial-medrev-study
#8
Géraldine Leguelinel-Blache, Christel Castelli, Clarisse Roux-Marson, Sophie Bouvet, Sandrine Andrieu, Philippe Cestac, Rémy Collomp, Paul Landais, Bertrice Loulière, Christelle Mouchoux, Rémi Varin, Benoit Allenet, Pierrick Bedouch, Jean-Marie Kinowski
BACKGROUND: Clinical pharmaceutical care has long played an important role in the improvement of healthcare safety. Pharmaceutical care is a collaborative care approach, implicating all the actors of the medication circuit in order to prevent and correct drug-related problems that can lead to adverse drug events. The collaborative pharmaceutical care performed during patients' hospitalization requires two mutually reinforcing activities: medication reconciliation and medication review...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29242497/silicon-cmos-architecture-for-a-spin-based-quantum-computer
#9
M Veldhorst, H G J Eenink, C H Yang, A S Dzurak
Recent advances in quantum error correction codes for fault-tolerant quantum computing and physical realizations of high-fidelity qubits in multiple platforms give promise for the construction of a quantum computer based on millions of interacting qubits. However, the classical-quantum interface remains a nascent field of exploration. Here, we propose an architecture for a silicon-based quantum computer processor based on complementary metal-oxide-semiconductor (CMOS) technology. We show how a transistor-based control circuit together with charge-storage electrodes can be used to operate a dense and scalable two-dimensional qubit system...
December 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/29220983/biomimetic-spiral-grating-for-stable-and-highly-efficient-absorption-in-crystalline-silicon-thin-film-solar-cells-erratum
#10
Jin Hou, Wei Hong, Xiaohang Li, Chunyong Yang, Shaoping Chen
In the original manuscript, the maximum short-circuit current in Fig. 2 and the description of angular stability for polarization in Fig. 6 are found incorrect owing to negligence. The incorrect maximum integrated absorption also led to errors appeared in Fig. 3 and Fig. 4(d), in which the mistake value was used to plot. In this erratum, all of those mistakes have been corrected. Moreover, both higher Fourier expansion order and the resolution of frequency are adopted in the recalculation to make sure the updated results to be reliable...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29213234/cognitive-mapping-based-on-conjunctive-representations-of-space-and-movement
#11
Taiping Zeng, Bailu Si
It is a challenge to build robust simultaneous localization and mapping (SLAM) system in dynamical large-scale environments. Inspired by recent findings in the entorhinal-hippocampal neuronal circuits, we propose a cognitive mapping model that includes continuous attractor networks of head-direction cells and conjunctive grid cells to integrate velocity information by conjunctive encodings of space and movement. Visual inputs from the local view cells in the model provide feedback cues to correct drifting errors of the attractors caused by the noisy velocity inputs...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/29094787/functional-dysconnectivity-of-the-limbic-loop-of-frontostriatal-circuits-in-first-episode-treatment-naive-schizophrenia
#12
Pan Lin, Xiaosheng Wang, Bei Zhang, Brian Kirkpatrick, Dost Öngür, James J Levitt, Jorge Jovicich, Shuqiao Yao, Xiang Wang
Frontostriatal circuits dysfunction has been implicated in the etiology and psychopathology of patients with schizophrenia (SZ). However, few studies have investigated SZ-related functional connectivity (FC) alterations in discrete frontostriatal circuits and their relationship with pathopsychology in first-episode schizophrenia (FESZ). The goal of this study was to identify dysfunctions in discrete frontostriatal circuits that are associated with key features of FESZ. To this end, a case-control, cross-sectional study was conducted, wherein resting-state (RS) functional magnetic resonance (fMRI) data were collected from 37 treatment-naïve FESZ patients and 29 healthy control (HC) subjects...
February 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/28949639/degeneracy-preserving-quantum-nondemolition-measurement-of-parity-type-observables-for-cat-qubits
#13
Joachim Cohen, W Clarke Smith, Michel H Devoret, Mazyar Mirrahimi
A central requirement for any quantum error correction scheme is the ability to perform quantum nondemolition measurements of an error syndrome, corresponding to a special symmetry property of the encoding scheme. It is in particular important that such a measurement does not introduce extra error mechanisms, not included in the error model of the correction scheme. In this Letter, we ensure such a robustness by designing an interaction with a measurement device that preserves the degeneracy of the measured observable...
August 11, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28947008/a-method-for-generating-3d-thermal-models-with-decoupled-acquisition
#14
Andriy Guilherme Krefer, Maiko Min Ian Lie, Gustavo Benvenutti Borba, Humberto Remigio Gamba, Marcos Dinís Lavarda, Mauren Abreu de Souza
BACKGROUND AND OBJECTIVE: Both thermal imaging and 3D scanning offer convenient advantages for medical applications, namely, being contactless, non-invasive and fast. Consequently, many approaches have been proposed to combine both sensing modalities in order to acquire 3D thermal models. The predominant approach is to affix a 3D scanner and a thermal camera in the same support and calibrate them together. While this approach allows straightforward projection of thermal images over the 3D mesh, it requires their simultaneous acquisition...
November 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28874706/synthesis-of-arbitrary-quantum-circuits-to-topological-assembly-systematic-online-and-compact
#15
Alexandru Paler, Austin G Fowler, Robert Wille
It is challenging to transform an arbitrary quantum circuit into a form protected by surface code quantum error correcting codes (a variant of topological quantum error correction), especially if the goal is to minimise overhead. One of the issues is the efficient placement of magic state distillation sub circuits, so-called distillation boxes, in the space-time volume that abstracts the computation's required resources. This work presents a general, systematic, online method for the synthesis of such circuits...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28820602/intricate-resonant-raman-response-in-anisotropic-res2
#16
Amber McCreary, Jeffrey R Simpson, Yuanxi Wang, Daniel Rhodes, Kazunori Fujisawa, Luis Balicas, Madan Dubey, Vincent H Crespi, Mauricio Terrones, Angela R Hight Walker
The strong in-plane anisotropy of rhenium disulfide (ReS2) offers an additional physical parameter that can be tuned for advanced applications such as logic circuits, thin-film polarizers, and polarization-sensitive photodetectors. ReS2 also presents advantages for optoelectronics, as it is both a direct-gap semiconductor for few-layer thicknesses (unlike MoS2 or WS2) and stable in air (unlike black phosphorus). Raman spectroscopy is one of the most powerful characterization techniques to nondestructively and sensitively probe the fundamental photophysics of a 2D material...
October 11, 2017: Nano Letters
https://www.readbyqxmd.com/read/28609480/an-automated-and-reliable-method-for-breath-detection-during-variable-mask-pressures-in-awake-and-sleeping-humans
#17
Chinh D Nguyen, Jason Amatoury, Jayne C Carberry, Danny J Eckert
Accurate breath detection is crucial in sleep and respiratory physiology research and in several clinical settings. However, this process is technically challenging due to measurement and physiological artifacts and other factors such as variable leaks in the breathing circuit. Recently developed techniques to quantify the multiple causes of obstructive sleep apnea, require intermittent changes in airway pressure applied to a breathing mask. This presents an additional unique challenge for breath detection...
2017: PloS One
https://www.readbyqxmd.com/read/28573311/kinematics-in-the-brain-unmasking-motor-control-strategies
#18
Liesjet E H Van Dokkum, D Mottet, I Laffont, A Bonafé, N Menjot de Champfleur, J Froger, E Le Bars
In rhythmical movement performance, our brain has to sustain movement while correcting for biological noise-induced variability. Here, we explored the functional anatomy of brain networks during voluntary rhythmical elbow flexion/extension using kinematic movement regressors in fMRI analysis to verify the interest of method to address motor control in a neurological population. We found the expected systematic activation of the primary sensorimotor network that is suggested to generate the rhythmical movement...
September 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28553479/a-dna-based-parity-generator-checker-for-error-detection-through-data-transmission-with-visual-readout-and-an-output-correction-function
#19
Daoqing Fan, Erkang Wang, Shaojun Dong
During any type of binary data transmission, the occurrence of bit errors is an inevitable and frequent problem suffered. These errors, which have fatal effects on the correct logic computation, especially in sophisticated logic circuits, can be checked through insertion of a parity generator (pG) at the transmitting end and a parity checker (pC) at the receiving end. Herein, taking even pG/pC as a model device, we constructed the first DNA-based molecular parity generator/checker (pG/pC) for error detection through data transmission, on a universal single-strand platform according to solely DNA hybridization...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28409953/quantum-state-transfer-via-noisy-photonic-and-phononic-waveguides
#20
B Vermersch, P-O Guimond, H Pichler, P Zoller
We describe a quantum state transfer protocol, where a quantum state of photons stored in a first cavity can be faithfully transferred to a second distant cavity via an infinite 1D waveguide, while being immune to arbitrary noise (e.g., thermal noise) injected into the waveguide. We extend the model and protocol to a cavity QED setup, where atomic ensembles, or single atoms representing quantum memory, are coupled to a cavity mode. We present a detailed study of sensitivity to imperfections, and apply a quantum error correction protocol to account for random losses (or additions) of photons in the waveguide...
March 31, 2017: Physical Review Letters
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