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Pregnant hypothermia

Juergen Pauluhn
This paper reviews the results from past regulatory and mechanistic inhalation studies in rats with the type II pyrethroid Cyfluthrin. Apart from many chemical irritants, Cyfluthrin was shown to be a neuroexcitatory agent without any inherent tissue-destructive or irritant property. Thus, any Cyfluthrin-induced neuroexcitatory afferent sensory stimulus from peripheral nociceptors in the upper respiratory tract is likely to be perceived as a transient stimulus triggering annoyance and/or avoidance by both rats and humans...
January 5, 2018: Toxicology Letters
Renata Jaccottet Freitas, Tiago Neuenfeld Munhoz, Iná da Silva Dos Santos, Flávio Sérgio Chiuchetta, Fernando Barros, Aline Coletto, Alicia Matijasevich
Objective: To evaluate providers' compliance with practice guidelines of prenatal and neonatal care in order to reduce neonatal mortality. Methods: Uncontrolled before-and-after study designed to evaluate changes that occurred between 2004 and 2012, after the interventions proposed by the Municipality Committee of Research on Child Deaths, Foetal and Maternal Death (COMAI) on the frequency of the process indicators for perinatal assistance improvement. A total of 254 patients were studied in 2004 and 259 patients in 2012...
October 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Nardhy Gomez-Lopez, Roberto Romero, Marcia Arenas-Hernandez, Bogdan Panaitescu, Valeria Garcia-Flores, Tara N Mial, Aashna Sahi, Sonia S Hassan
OBJECTIVE: Intra-amniotic infection is associated with spontaneous preterm labor. In most cases, the infection is subclinical and bacteria are detected in the amniotic cavity rather than in the chorioamniotic membranes. The aims of this study were to establish a model of intra-amniotic lipopolysaccharide (LPS)-induced preterm labor/birth that resembles the subclinical syndrome and to compare this model to two established models of LPS-induced preterm labor/birth. METHODS: Pregnant B6 mice received an intra-amniotic, intra-uterine, or intra-peritoneal injection of LPS (100 ng/amniotic sac, 15 μg/25 μL, and 15 μg/200 μL respectively) or PBS (control)...
February 2018: Journal of Maternal-fetal & Neonatal Medicine
Paul D Trethowan, Tom Hart, Andrew J Loveridge, Anna Haw, Andrea Fuller, David W Macdonald
Mammals use endogenously produced heat to maintain a high and relatively constant core body temperature (Tb ). How they regulate their Tb during reproduction might inform us as to what thermal conditions are necessary for optimal development of offspring. However, few studies have measured Tb in free-ranging animals for sufficient periods of time to encounter reproductive events. We measured Tb continuously in six free-ranging adult female African lions (Panthera leo) for approximately 1 year. Lions reduced the 24 h amplitude of Tb by about 25% during gestation and decreased mean 24 h Tb by 1...
November 2016: Biology Letters
Michael J Murray, Heidi DeBlock, Brian Erstad, Anthony Gray, Judi Jacobi, Che Jordan, William McGee, Claire McManus, Maureen Meade, Sean Nix, Andrew Patterson, M Karen Sands, Richard Pino, Ann Tescher, Richard Arbour, Bram Rochwerg, Catherine Friederich Murray, Sangeeta Mehta
OBJECTIVE: To update the 2002 version of "Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient." DESIGN: A Task Force comprising 17 members of the Society of Critical Medicine with particular expertise in the use of neuromuscular-blocking agents; a Grading of Recommendations Assessment, Development, and Evaluation expert; and a medical writer met via teleconference and three face-to-face meetings and communicated via e-mail to examine the evidence and develop these practice guidelines...
November 2016: Critical Care Medicine
Shinsuke Koyama, Koichiro Okuno, Hirokazu Naoi, Masahiro Watanabe, Kimiaki Ozaki, Yasuhiko Shiki
Lymphocytic adenohypophysitis is a very rare autoimmune disease characterized by an anterior pituitary infiltration of lymphocytes that cause various symptoms, such as headache, visual disturbance, and hypopituitarism. Lymphocytic adenohypophysitis is more common in women and has a remarkable association with the perinatal period. Recently, we experienced a case of lymphocytic adenohypophysitis shortly after delivery. A 37-year-old primiparous woman delivered her baby at 38 weeks' gestation. The next morning, she presented symptoms of hypoglycemia and hypothermia...
April 2016: Journal of Obstetrics and Gynaecology Research
Patrick Burns, Hai Lun Liu, Shikha Kuthiala, Gilles Fecteau, André Desrochers, Lucien Daniel Durosier, Mingju Cao, Martin G Frasch
The chronically instrumented pregnant sheep has been used as a model of human fetal development and responses to pathophysiologic stimuli such as endotoxins, bacteria, umbilical cord occlusions, hypoxia and various pharmacological treatments. The life-saving clinical practices of glucocorticoid treatment in fetuses at risk of premature birth and the therapeutic hypothermia have been developed in this model. This is due to the unique amenability of the non-anesthetized fetal sheep to the surgical placement and maintenance of catheters and electrodes, allowing repetitive blood sampling, substance injection, recording of bioelectrical activity, application of electric stimulation and in vivo organ imaging...
October 25, 2015: Journal of Visualized Experiments: JoVE
Kevin N Oguayo, Ola O Oyetayo, David Stewart, Steven M Costa, Richard O Jones
Out-of-hospital cardiac arrest is a leading cause of death in the United States. Pregnant women are not immune to cardiac arrest, and the treatment of such patients can be difficult. Pregnancy is a relative contraindication to the use of therapeutic hypothermia after cardiac arrest. A 20-year-old woman who was 18 weeks pregnant had an out-of-hospital cardiac arrest. Upon her arrival at the emergency department, she was resuscitated and her circulation returned spontaneously, but her score on the Glasgow Coma Scale was 3...
August 2015: Texas Heart Institute Journal
Satoshi Furukawa, Naho Tsuji, Seigo Hayashi, Masayoshi Abe, Souichiro Hagio, Yoshikazu Yamagishi, Yusuke Kuroda, Akihiko Sugiyama
The effects of chlorpromazine-treatment timing on the development of the placenta in pregnant rats were examined. Chlorpromazine was administered intraperitoneally at 100mg/kg on gestation day (GD) 11 (GD11-treated group), GD 13 (GD13-treated group) or GD 15 (GD15-treated group) into pregnant rats. All treated dams exhibited decreased body weight, prone position, hypothermia, loss or decrease of locomotor activity, etc. The fetal mortality rates were increased up to 42.9% in the GD11- and GD13-treated groups and up to 16...
September 2015: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
Shi-Min Yuan
Infective Endocarditis (IE) during pregnancy is a rare but grave condition. The diagnosis and management can be challenging, especially when the pregnant patient warrants a cardiac operation under cardiopulmonary bypass. The present article describes IE during pregnancy based on a series of published case reports in the literature. IE during pregnancy often causes embolic events and mycotic aneurysms. Two-thirds of IE in the pregnant patients requires timely or urgent cardiac surgery to alleviate patients' deterioration...
February 2015: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Erin C Hunter, Jennifer A Callaghan-Koru, Abdullah Al Mahmud, Rashed Shah, Azadeh Farzin, Elizabeth A Cristofalo, Sadika Akhter, Abdullah H Baqui
Bangladesh has one of the world's highest rates of low birth weight along with prevalent traditional care practices that leave newborns highly vulnerable to hypothermia, infection, and early death. We conducted formative research to explore existing newborn care practices in rural Bangladesh with an emphasis on thermal protection, and to identify potential facilitators, barriers, and recommendations for the community level delivery of kangaroo mother care (CKMC). Forty in-depth interviews and 14 focus group discussions were conducted between September and December 2012...
December 2014: Social Science & Medicine
Lisa Groff Paris, Melody Seitz, Katie G McElroy, Mary Regan
OBJECTIVE: To examine the effect of various warming methods during cesarean birth (CB) on maternal core body temperature, maternal hypothermia, and other maternal and neonatal outcomes. DESIGN: Three-arm randomized controlled trial. SETTING: Perinatal unit in a large community hospital in the mid-Atlantic United States. PARTICIPANTS: Two hundred twenty-six (226) pregnant women undergoing planned CB. METHODS: Women were randomly assigned to one of three groups (usual care, warmed fluids, or warmed underbody pad)...
November 2014: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
A Chakladar, M J Dixon, D Crook, C M Harper
BACKGROUND: The adverse effects of inadvertent perioperative hypothermia in the surgical population are well established. The aim of this study was to investigate whether a resistive warming mattress would reduce the incidence of inadvertent perioperative hypothermia in patients undergoing elective caesarean section. METHODS: A total of 116 pregnant women booked for elective caesarean section were randomised to either intraoperative warming with a mattress or control...
November 2014: International Journal of Obstetric Anesthesia
Rovana Paludo Toyama, João Carlos Xikota, Marcelo L Schwarzbold, Tania Silvia Frode, Ziliani da Silva Buss, Jean Costa Nunes, Gabriela Di Giunta Funchal, Fernanda Costa Nunes, Roger Walz, Maria Marlene de Souza Pires
OBJECTIVE: Clinical and experimental evidences indicate that intrauterine inflammation during pregnancy is associated to brain damage. The objective of this study is to determine the effects of lipopolysaccharide in temperature, cytokine production and sickness behavior of pregnant dams. METHODS: A single i.p. injection of lipopolysaccharide (LPS) (50, 150 or 300 µg/kg) was administered on E18. Controls received isotonic saline. Body temperature was controlled before and 3 h after injections...
March 2015: Journal of Maternal-fetal & Neonatal Medicine
S-M Yuan
Background: Cardiac operations in pregnant patients are a challenge for physicians in multidisciplinary teams due to the complexity of the condition which affects both mother and baby. Management strategies vary on a case-by-case basis. Feto-neonatal and maternal outcomes after cardiopulmonary bypass (CPB) in pregnancy, especially long-term follow-up results, have not been sufficiently described. Methods: This review was based on a complete literature retrieval of articles published between 1991 and April 30, 2013...
January 2014: Geburtshilfe und Frauenheilkunde
Meharban Singh
Neonates truly constitute the foundation of a nation and no sensible government can afford to neglect their needs and rights. In the last 50 y, technology has revolutionized neonatology and we have moved from an exceedingly passive or "hands-off" philosophy to an extremely aggressive or mechanistic approach. Deaths during first 28 d of life account for over 60 % of all infant deaths and 40 % of all deaths of under-5 children. If we have to further reduce infant mortality rate in our country we must focus our strategies to improve health and survival of newborn babies...
June 2014: Indian Journal of Pediatrics
Suada Brankovic, Amra Macak Hadziomerovic, Admir Rama, Mersa Segalo
INTRODUCTION: Premature baby (praematurus, neonatus praetemporarius) indicates infant that is born before 37 full weeks of gestation, calculated from the first day of the last mother's menstruation. Premature baby is characterized by immaturity of its organs and tissues, which can lead to an immediate or later threat. Premature children cannot keep the body temperature and very quickly gets hypothermia. This is due to the low creation of heat, but also because of the great loss of heat through the thin skin, which lacks fat...
2013: Medical Archives
Mangwi Richard Ayiasi, Kathleen Van Royen, Roosmarijn Verstraeten, Lynn Atuyambe, Bart Criel, Christopher Orach Garimoi, Patrick Kolsteren
BACKGROUND: Neonatal death accounts for one fifth of all under-five mortality in Uganda. Suboptimal newborn care practices resulting from hypothermia, poor hygiene and delayed initiation of breastfeeding are leading predisposing factors. Evidence suggests focused educational prenatal care messages to mitigate these problems. However, there is a paucity of data on the interaction between the service provider and the prenatal service user. This study aims to understand the scope of educational information and current practices on newborn care from the perspectives of prenatal mothers and health workers...
2013: BMC Pregnancy and Childbirth
N Schlabritz-Loutsevitch, G Hubbard, J Zhang, S Gupta, E Dick
INTRODUCTION: Abruptio placentae, defined as premature separation of a normally implanted placenta, is a life threatening pregnancy complication with unknown pathophysiology. A history of abruptio placentae is the major risk factor for this pregnancy complication in humans. We describe the first case of recurrent abruptio placentae in a Macaca fascicularis. MATERIAL AND METHODS: A pregnant M. fascicularis at term gestation was presented with weakness and hypothermia...
April 2013: Placenta
L Bosch, M M Rivera del Álamo, A Andaluz, L Monreal, C Torrente, F García-Arnas, L Fresno
Intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP) have shown clinical relevance in monitoring critically ill human beings submitted to abdominal surgery. Only a few studies have been performed in veterinary medicine. The aim of this study was to assess how pregnancy and abdominal surgery may affect IAP and APP in healthy cats. For this purpose, pregnant (n=10) and non-pregnant (n=11) queens undergoing elective spaying, and tomcats (n=20, used as controls) presented for neutering by scrotal orchidectomy were included in the study...
December 15, 2012: Veterinary Record
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