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drug eluting stents

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https://www.readbyqxmd.com/read/28748156/the-optimal-duration-of-dual-antiplatelet-therapy-after-implantation-of-drug-eluting-coronary-stents-an-unanswered-question
#1
EDITORIAL
Cristina Aurigemma, Francesco Burzotta, Carlo Trani
No abstract text is available yet for this article.
June 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28745576/association-of-cyp2c19-2-polymorphism-with-clopidogrel-response-and-1-year-major-adverse-cardiovascular-events-in-a-multiethnic-population-with-drug-eluting-stents
#2
Shirley Siang Ning Tan, Alan Yean Yip Fong, Melissa Mejin, Jerry Gerunsin, Khai Liy Kong, Felicia Yien Yin Chin, Lee Len Tiong, Melissa Siaw Han Lim, Asri Said, Ning Zan Khiew, Chi Yen Voon, Nor Hanim Mohd Amin, Yee Ling Cham, Keng Tat Koh, Yen Yee Oon, Tiong Kiam Ong
BACKGROUND: Patients undergoing elective percutaneous coronary intervention (PCI) with drug-eluting stents (DES) who have impaired clopidogrel response, have a higher risk of subsequent major adverse cardiovascular events (MACE). AIM OF THE STUDY: To establish the relationship between CYP2C19 genotype, clopidogrel responsiveness and 1-year MACE. MATERIALS & METHODS: Aspirin/clopidogrel responses were assessed with Multiplate Analyzer and CYP2C19*2 allele by SpartanRx...
July 26, 2017: Pharmacogenomics
https://www.readbyqxmd.com/read/28741575/the-drug-eluting-absorbable-magnesium-vascular-scaffold-in-complex-coronary-bifurcations-insights-from-an-in-vivo-multimodality-imaging-study
#3
Johan Bennett, Maarten Vanhaverbeke, Nina Vanden Driessche, Nick Hiltrop, Tom Adriaenssens, Walter Desmet, Peter Sinnaeve, Christophe Dubois
AIMS: This acute in-vivo study sought to provide insights regarding the feasibility of performing complex bifurcation stenting with Magmaris magnesium-alloy bioresorbable scaffolds (Biotronik,Bulach, Switzerland). METHODS AND RESULTS: Twenty-five New-Zealand-White rabbits underwent stenting of non-diseased aorto-iliac bifurcations with Magmaris using provisional (PS,n=5), culotte (n=6), modified-T (n=6), or T-and-protrusion (TAP,n=8) stenting techniques. Angiography, optical coherence tomography and micro-computed tomography were performed...
July 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28740709/outcomes-of-a-hybrid-approach-of-percutaneous-coronary-intervention-followed-by-minimally-invasive-aortic-valve-replacement
#4
Orlando Santana, Steve Xydas, Roy F Williams, Angelo LaPietra, Maurice Mawad, Gerald P Rosen, Nirat Beohar, Christos G Mihos
BACKGROUND: In patients requiring coronary revascularization and aortic valve replacement, a combined approach of percutaneous coronary intervention followed by minimally invasive aortic valve replacement may be a viable treatment strategy. METHODS: The outcomes of 123 consecutive patients with significant coronary artery and aortic valve disease, who underwent percutaneous coronary intervention followed by elective minimally invasive aortic valve replacement between February 2009 and April 2014, were retrospectively evaluated...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28732815/2-year-outcomes-with-the-absorb-bioresorbable-scaffold-for-treatment-of-coronary-artery-disease-a-systematic-review-and-meta-analysis-of-seven-randomised-trials-with-an-individual-patient-data-substudy
#5
Ziad A Ali, Patrick W Serruys, Takeshi Kimura, Runlin Gao, Stephen G Ellis, Dean J Kereiakes, Yoshinobu Onuma, Charles Simonton, Zhen Zhang, Gregg W Stone
BACKGROUND: Bioresorbable vascular scaffolds (BVS) offer the potential to improve long-term outcomes of percutaneous coronary intervention after their complete bioresorption. Randomised trials have shown non-inferiority between BVS and metallic drug-eluting stents at 1 year in composite safety and effectiveness outcomes, although some increases in rates of target vessel-related myocardial infarction and device thrombosis were identified. Outcomes of BVS following the first year after implantation are unknown...
July 18, 2017: Lancet
https://www.readbyqxmd.com/read/28731889/stent-thrombosis-with-bioabsorbable-polymer-drug-eluting-stents-insights-from-the-food-and-drug-administration-database
#6
Abdur R Khan, Avnish Tripathi, Talha A Farid, Bilal Abaid, Deepak L Bhatt, Jon R Resar, Michael P Flaherty
BACKGROUND: SYNERGY, a bioabsorbable polymer-based, everolimus-eluting stent (BP-DES), recently received regulatory approval in the USA for use in percutaneous coronary interventions. Yet, information on the safety of BP-DES in routine clinical practice is limited. Our aim was to compare the safety of the recently approved BP-DES with current durable polymer drug-eluting stents (DP-DES) by analyzing adverse events, namely, stent thrombosis (ST), reported to the Manufacturer and User Facility Device Experience (MAUDE) database...
July 20, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28729378/very-early-great-saphenous-vein-graft-aneurysm-treated-by-percutaneous-coronary-intervention-under-chromaflo-imaging-guidance
#7
Tetsuo Yamaguchi, Takamichi Miyamoto, Kandoh Kawahatsu, Toshihiro Nozato
A 73-year-old man, who had undergone coronary artery bypass grafting (CABG) 10 days prior, presented with a great saphenous vein graft aneurysm (SVGA). CT revealed the increasing size of the aneurysm. Since the SVGA occurred immediately after CABG and there were no other complications, the aneurysm was treated percutaneously. While intravascular ultrasonography (IVUS) and optical coherence tomography failed to detect the entry point, an IVUS catheter with the addition of ChromaFlo imaging clearly revealed the entry point, size and length of the SVGA...
July 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28728650/first-report-of-the-resolute-onyx-2-0-mm%C3%A2-zotarolimus-eluting-stent-for-the-treatment-of-coronary-lesions-with-very%C3%A2-small-reference-vessel-diameter
#8
Matthew J Price, Shigeru Saito, Richard A Shlofmitz, Douglas J Spriggs, Michael Attubato, Brent McLaurin, Alexandra Popma Almonacid, Sandeep Brar, Minglei Liu, Elizabeth Moe, Roxana Mehran
OBJECTIVES: The aim of this study was to explore the safety and efficacy of a dedicated drug-eluting stent for the treatment of coronary lesions with very small reference vessel diameter (RVD). BACKGROUND: Smaller RVD is associated with increased risk for restenosis and target lesion failure (TLF) after stent implantation. METHODS: This was a prospective, single-arm, multicenter trial of the Resolute Onyx 2.0-mm zotarolimus-eluting stent. The primary endpoint was 12-month TLF, which was compared with a pre-specified performance goal...
July 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28725329/ticagrelor-associated-conduction-disorder-a-case-report-and-review-of-the-literature
#9
Mustafa Yurtdas, Mahmut Ozdemir
A 47-year-old female presented to emergency clinic due to non-ST-elevation myocardial infarction (NSTEMI). After receiving acetylsalicylic acid, a loading dose of ticagrelor 180 mg and intravenous unfractionated heparin, she underwent successful placement of drug eluting stent on the distal part of non-dominant left circumflex artery. The patient had no pre-existing atrioventricular (AV) block and did not use AV blocking agent. Approximately 10 h after taking a loading dose of ticagrelor, baseline normal rhythm degenerated to the first and then complete AV block, with mild dizziness...
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28724504/total-evidence-for-drug-eluting-stent-efficacy-and-safety-in-stemi-patients
#10
EDITORIAL
Guido Parodi
No abstract text is available yet for this article.
July 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28724348/efficacy-and-safety-of-polymer-free-stent-versus-polymer-permanent-drug-eluting-stent-in-patients-with-acute-coronary-syndrome-a-meta-analysis-of-randomized-control-trials
#11
Kang Gao, Yiguang Sun, Ming Yang, Ling Han, Liwei Chen, Wenze Hu, Ping Chen, Xiaohong Li
BACKGROUND: The efficacy and safety of polymer-free stent (PFS) versus permanent polymer drug-eluting stent (PPDES) in patients undergoing percutaneous coronary intervention (PCI) remain controversial. Our meta-analysis was undertaken to evaluate and compare the efficacy and safety of PFS with those of PPDES in patients undergoing PCI. METHODS: We searched PubMed, Cochrane Library, EMBASE, and Clinical Trials.gov databases for randomized controlled trials (RCTs)...
July 19, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28722295/prevalence-correlates-and-impact-of-coronary-calcification-on-adverse-events-following-pci-with-newer-generation-des-findings-from-a-large-multiethnic-registry
#12
Robert S Copeland-Halperin, Usman Baber, Melissa Aquino, Anitha Rajamanickam, Swathi Roy, Choudhury Hasan, Nitin Barman, Jason C Kovacic, Pedro Moreno, Prakash Krishnan, Joseph M Sweeny, Roxana Mehran, George Dangas, Annapoorna S Kini, Samin K Sharma
OBJECTIVES: We sought to determine the prevalence, predictors, and clinical impact of target lesion calcification in patients undergoing percutaneous coronary intervention (PCI) with newer generation drug-eluting stents (DES) and devices. BACKGROUND: Coronary calcification is independently associated with adverse outcomes following PCI. While newer DES and contemporary devices are considered safer and more efficacious, their influence on outcomes following PCI of heavily calcified lesions is unknown...
July 19, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28722266/second-generation-drug-eluting-stents-versus-bare-metal-stents-for-percutaneous-coronary-intervention-of-the-proximal-left-anterior-descending-artery-an-analysis-of-the-basket-prove-i-and-ii-trials
#13
Fernanda Marinho Mangione, Tor Biering-Sørensen, Kotaro Nochioka, Tannas Jatene, Odilson Marcos Silvestre, Kim Wadt Hansen, Rikke Sørensen, Jan Skov Jensen, Peter Godsk Jorgensen, Raban Jeger, Christoph Kaiser, Matthias Pfisterer, Søren Galatius
OBJECTIVES: To compare mid-term outcomes between patients undergoing proximal left anterior descending artery (LAD) percutaneous coronary intervention (PCI) with second generation drug-eluting stent (DES) or bare-metal stent (BMS). BACKGROUND: PCI with BMS and first-generation DES have shown to be safe options for the treatment of proximal LAD stenosis, however associated with considerable reintervention rates. Overall, second-generation DES has proven to be superior to BMS and first-generation DES, nevertheless, its effect for proximal LAD PCI has not previously been reported...
July 19, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28720725/optical-coherence-tomography-findings-in-patients-with-coronary-stent-thrombosis-a-report-of-the-prevention-of-late-stent-thrombosis-by-an-interdisciplinary-global-european-effort-prestige-consortium
#14
Tom Adriaenssens, Michael Joner, Thea Godschalk, Nikesh Malik, Fernando Alfonso, Erion Xhepa, Dries De Cock, Kenichi Komukai, Tomohisa Tada, Javier Cuesta, Vasile Sirbu, Laurent J Feldman, Franz-Josef Neumann, Alison H Goodall, Ton Heestermans, Ian Buysschaert, Ota Hlinomaz, Ann Belmans, Walter Desmet, Jurrien M Ten Berg, Anthony H Gershlick, Steffen Massberg, Adnan Kastrati, Giulio Guagliumi, Robert Byrne
Background -Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods -Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed with frequency domain OCT...
July 18, 2017: Circulation
https://www.readbyqxmd.com/read/28716428/high-intensity-statin-treatments-in-clinically-stable-patients-on-aspirin-monotherapy-12-months-after-drug-eluting-stent-implantation-a-randomized-study
#15
Eui Im, Yun-Hyeong Cho, Yongsung Suh, Deok-Kyu Cho, Ae-Young Her, Yong Hoon Kim, Kyounghoon Lee, Woong Chol Kang, Kyeong Ho Yun, Sang-Yong Yoo, Sang-Sig Cheong, Dong-Ho Shin, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
INTRODUCTION AND OBJECTIVES: Current guidelines on the treatment of blood cholesterol recommend continuous maintenance of high-intensity statin treatment in drug-eluting stent (DES)-treated patients. However, high-intensity statin treatment is frequently underused in clinical practice after stabilization of DES-treated patients. Currently, the impact of continuous high-intensity statin treatment on the incidence of late adverse events in these patients is unknown. We investigated whether high-intensity statin treatment reduces late adverse events in clinically stable patients on aspirin monotherapy 12 months after DES implantation...
July 14, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28714525/dedicated-bifurcation-stents-or-regular-drug-eluting-stents-in-distal-left-main-stenosis-a-retrospective-study
#16
Adam Kern, Robert J Gil, Krystian Bojko, Bartłomiej Rzeszowski, Krzysztof Bednarski, Jerzy Górny, Jacek Bil
BACKGROUND: Mainly atherosclerosis develops in distal left main (LM) within bifurcation or trifurcation. The aim of this study was to analyze the strategy of distal LM stenosis treatment and associated clinical outcomes in a large hospital in Northern Poland. METHODS: The study population consisted of consecutive patients with stable coronary artery disease or acute coronary syndrome (ACS) and distal LM stenosis who were hospitalized between June 2012 and June 2013...
July 17, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28708023/comparison-of-drug-eluting-balloon-angioplasty-with-self-expanding-interwoven-nitinol-stent-deployment-in-patients-with-complex-femoropopliteal-lesions
#17
Burak Teymen, Suleyman Akturk, Ulku Akturk, Muhammed Tdjani
Objective The aim of this study was to compare the drug-eluting balloon with self-expanding interwoven nitinol stent deployment in patients with complex femoropopliteal lesions. Methods We retrospectively identified patients at our clinic with complex femoropopliteal artery lesions treated either with self-expanding interwoven nitinol stent or drug-eluting balloon. All patients had ankle-brachial index measured before and after the intervention, and regular clinical follow-up with Doppler ultrasonography was performed at six months and one year...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28707443/cardiac-transplant-vasculopathy
#18
EDITORIAL
Jonathan M Tobis
Transplant vasculopathy is a form of slowly progressive rejection. The interventional cardiologist plays an important role in maintaining survival of this precious commodity by performing PCI. Everolimus drug eluting stents are highly effective and have relatively low occurrence of in-stent restenosis, but transplant vasculopathy continues to progress in a diffuse pattern.
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28707379/three-and-6-month-optical-coherence-tomographic-surveillance-following-percutaneous-coronary-intervention-with-the-angiolite%C3%A2-drug-eluting-stent-the-anchor-study
#19
Rishi Puri, Imanol Otaegui, Manel Sabaté, Antonio Serra-Peñaranda, Marti Puigfel, Armando Perez de Prado, Luis Nombela-Franco, Jose M de la Torre Hernandez, Rosario Ortas Nadal, Andres Iniguez-Romo, Gustavo Jiménez, Felipe Fernandez-Vazquez, Carlos Cuellas-Ramon, Nieves Gonzalo, Victor Alfonso Jiménez Diaz, Lluis Duocastella, Maria Molina, Marc Amoros, Isabel Perez, Alberto Barria Perez, Emilie Pelletier Beaumont, Stephen J Nicholls, Bruno Garcia Del Blanco, Josep Rodés-Cabau
BACKGROUND: Pre-clinical results of a novel open-cell, thin strut, durable polymer, laser cut cobalt chromium sirolimus-eluting stent (Angiolite) were promising. Using quantitative optical coherence tomographic (OCT) analyses, we explored the healing characteristics of the Angiolite DES system at 3- and 6-months post implantation. METHODS: A total of 103 patients with de novo coronary lesions underwent percutaneous coronary intervention with the Angiolite DES and were randomized 1:3 into two cohorts for angiographic and OCT follow-up, with 28 and 70 patients returning for 3- or 6-month post-PCI surveillance, respectively...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28707375/clinical-outcomes-with-reservoir-based-polymer-free-amphilimus-eluting-stents-in-real-world-patients-according-to-diabetes-mellitus-and-complexity-the-investig8-registry
#20
Gennaro Sardella, Pieter Stella, Mauro Chiarito, Antonio M Leone, Vruyr Balian, Franco Prosperi, Giovanni Sorropago, Massimo Mancone, Simone Calcagno, Carlo Briguori, Giulio G Stefanini
BACKGROUND: Patients with diabetes mellitus (DM) remain at higher risk of restenosis after percutaneous coronary intervention despite the use of contemporary drug-eluting stents. The Cre8 amphilimus-eluting stent (AES) has shown promising results in DM patients. Whether this holds true irrespective of patient's clinical and angiographic complexity is unknown. METHODS: Five hundred and ninety five consecutive patients (738 lesions) undergoing AES implantation were included in the INVESTIG8 multicenter registry...
July 14, 2017: Catheterization and Cardiovascular Interventions
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