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Metal allergy

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https://www.readbyqxmd.com/read/28913542/metal-release-profiles-of-orthodontic-bands-brackets-and-wires-an-in-vitro-study
#1
B Wendl, H Wiltsche, E Lankmayr, H Winsauer, A Walter, A Muchitsch, N Jakse, M Wendl, T Wendl
AIM: The present study evaluated the temporal release of Co Cr, Mn, and Ni from the components of a typical orthodontic appliance during simulated orthodontic treatment. MATERIALS AND METHODS: Several commercially available types of bands, brackets, and wires were exposed to an artificial saliva solution for at least 44 days and the metals released were quantified in regular intervals using inductively coupled plasma quadrupole mass spectrometry (ICP-MS, Elan DRC+, Perkin Elmer, USA)...
September 14, 2017: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/28886415/burden-of-higher-lead-exposure-in-african-americans-starts-in-utero-and-persists-into-childhood
#2
Andrea E Cassidy-Bushrow, Alexandra R Sitarik, Suzanne Havstad, Sung Kyun Park, Lawrence F Bielak, Christine Austin, Christine Cole Johnson, Manish Arora
BACKGROUND: Recent public health lead crises in urban areas emphasize the need to better understand exposure to environmental toxicants, particularly in higher risk groups. Although African-American children have the highest prevalence of elevated blood lead levels in the United States, little is known about when this trajectory of disproportionate burden of lead exposure first emerges. OBJECTIVES: Using tooth-matrix biomarkers that directly measure fetal and early childhood metal levels, the primary goal of this study was to determine if there were racial disparities in lead levels during fetal development and early childhood...
September 5, 2017: Environment International
https://www.readbyqxmd.com/read/28875355/is-there-an-association-between-flow-diverter-fish-mouthing-and-delayed-type-hypersensitivity-to-metals-a-case-control-study
#3
Naci Kocer, Prabath Kumar Mondel, Elif Yamac, Ayse Kavak, Osman Kizilkilic, Civan Islak
PURPOSE: Flow diverters are increasingly used in the treatment of complex and giant intracranial aneurysms. However, they are associated with complications like late aneurysmal rupture. Additionally, flow diverters show focal structural decrease in luminal diameter without any intimal hyperplasia. This resembles a "fish mouth" when viewed en face. In this pilot study, we tested the hypothesis of a possible association between flow diverter fish-mouthing and delayed-type hypersensitivity to its metal constituents...
September 5, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28870053/-domestic-external-fixator-application-in-the-treatment-of-limb-deformities-7-289-cases-application-report
#4
S H Qin, B F Guo, X J Zheng, S F Jiao, H T Xia, A M Peng, Q Pan, J C Zang, Z J Wang
Objective: To discuss the clinical application and effects of domestic external fixator in the treatment of patients with malformations of limbs. Methods: A total of 7 289 patients with malformation of limbs who had been operated in Qin Sihe orthopedic surgery team from January 1989 to June 2016 were retrospective analyzed. The patients were treated with domestic external fixator, including 4 033 males and 3 256 females, aging from 2 to 82 years with a mean age of 23.4 years. There were 2 732 patients using Ilizarov external fixator, 4 713 patients using hybrid external fixator, 57 patients using monobrachial external fixator, 232 patients using Ilizarov external fixator and hybrid external fixator...
September 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28841289/nanoscale-zeolitic-imidazolate-framework-8-as-efficient-vehicles-for-enhanced-delivery-of-cpg-oligodeoxynucleotides
#5
Huijie Zhang, Wei Chen, Kai Gong, Jinghua Chen
CpG oligodeoxynucleotides (ODNs) activate the immune system and induce Th 1 responses by stimulation of Toll-like receptor 9 (TLR9). Thus, CpG ODNs have become immunotherapeutics against various diseases including cancers, allergies, and infection. However, applications of CpG ODNs are largely limited because of their easy degradation by DNase as well as inefficient cellular uptake. Development of efficient delivery systems capable of transferring CpG ODNs into immune cells is important to enhance their therapeutic efficacy...
September 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28812014/surgical-approach-may-influence-survival-of-large-diameter-head-metal-on-metal-total-hip-arthroplasty-a-6-to-10-year-follow-up-study
#6
Chih-Chien Hu, Tsan-Wen Huang, Shih-Jie Lin, Po-Chun Lin, Feng-Chih Kuo, Kuo-Ti Peng, Kuo-Chin Huang, Hsin-Nung Shih, Mel S Lee
Large-diameter head (LDH) metal-on-metal (MoM) total hip arthroplasty (THA) has lost popularity because of metal allergy or ALTRs (adverse local tissue reactions) in the past decade. Whether the surgical approach may influence the survival of LDH-MoM-THA has not been reported. From 2006 to 2009, we performed 96 LDH-MoM-THAs on 80 patients using an in situ head-neck assembly technique through a modified Watson-Jones approach. With a mean follow-up of 8.4 years (range, 6.3-10.1 years), the implant survival rate was 100%...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28806494/body-piercing-motivations-and-implications-for-health
#7
REVIEW
Cheri Van Hoover, Carol-Ann Rademayer, Cindy L Farley
Body piercing has evolved from a behavior once considered extreme to an accepted choice among the general population. Earlobe piercing is so common that it is now considered a normative behavior. The motivations for choosing body piercing have changed and are associated with piercing site and number of piercings chosen by the individual. Meanings ascribed to body piercing were traditionally related to enhanced sexual desirability and experience, but now range from the innocuous, such as a fashion statement, to the risk laden, such as nonsuicidal self-injury...
August 14, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28804748/health-of-children-living-near-coal-ash
#8
Clara G Sears, Kristina M Zierold
Coal ash, generated from coal combustion, is composed of small particles containing metals and other elements, such as metalloids. Coal ash is stored in open-air impoundments, frequently near communities. The objective of this study was to evaluate the prevalence of health and sleep problems in children living near coal ash and compare these prevalences to children not living near coal ash. In 2013 to 2014, we conducted a cross-sectional survey in a community adjacent to coal ash storage sites and a community not exposed to coal ash...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28795428/are-metals-involved-in-tattoo-related-hypersensitivity-reactions-a-case-report
#9
Christa de Cuyper, Evelyne Lodewick, Ines Schreiver, Bernhard Hesse, Christian Seim, Hiram Castillo-Michel, Peter Laux, Andreas Luch
BACKGROUND: Allergic reactions to tattoos are not uncommon. However, identification of the culprit allergen(s) remains challenging. OBJECTIVES: We present a patient with papulo-nodular infiltration of 20-year-old tattoos associated with systemic symptoms that disappeared within a week after surgical removal of metal osteosynthesis implants from his spine. We aimed to explore the causal relationship between the metal implants and the patient's clinical presentation...
August 9, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28776630/metal-allergy-as-a-cause-of-implant-failure-in-shoulder-arthroplasty
#10
Jia-Wei Kevin Ko, Thema A Nicholson, C Edward Hoffler, Gerald Williams, Charles Getz
Metal allergy is an uncommon and poorly understood cause of failure of orthopedic implants. To the authors' knowledge, there have been no reports of the management of shoulder arthroplasty patients with metal allergy. The authors present their experience with the diagnosis and management of patients with metal allergy. Patients with metal allergy undergoing shoulder arthroplasty were identified through retrospective chart review from January 1, 2012, to January 31, 2015. Case characteristics collected included patient risk factors (age, sex, prior cutaneous reactions to metal), metal allergy factors (type of metal allergy, method of diagnosis), and surgery factors (implant type, primary/revision, type of shoulder arthroplasty)...
August 3, 2017: Orthopedics
https://www.readbyqxmd.com/read/28709788/making-sense-of-metal-allergy-and-hypersensitivity-to-metallic-implants-in-relation-to-hand-surgery
#11
REVIEW
Thomas J Christensen, Shefali A Samant, Alexander Y Shin
All metals implanted into a biological system undergo some degree of corrosion depending upon its composition. The electrochemical process of corrosion produces free metal ions, which may activate the host's immune system through a variety of mechanisms. Whereas dermal metal hypersensitivity is common, affecting 10% to 15% of the population, the immune reaction from implanted metals is much less common (< 0.1%), but has been associated with metal allergy and hypersensitivity producing a multitude of patient symptoms...
September 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28675503/a-population-based-study-of-self-reported-skin-exposures-and-symptoms-in-relation-to-contact-allergy-in-adolescents
#12
Maria Lagrelius, Carl-Fredrik Wahlgren, Mihály Matura, Anna Bergström, Inger Kull, Carola Lidén
BACKGROUND: Knowledge about the relations between skin exposures, skin symptoms and contact allergy in adolescents is limited. OBJECTIVES: To explore self-reported skin exposures and skin symptoms in girls and boys, and to assess the associations between exposures, symptoms and contact allergy at age 16 years. PARTICIPANTS AND METHODS: In all, 3115 adolescents from the population-based BAMSE birth cohort answered a questionnaire at age 16 concerning various skin exposures and related skin symptoms...
July 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28675438/biological-monitoring-of-dermal-and-air-exposure-to-cobalt-at-a-swedish-hard-metal-production-plant-does-dermal-exposure-contribute-to-uptake
#13
Maria Klasson, Magnus Lindberg, Ing-Liss Bryngelsson, Helena Arvidsson, Carin Pettersson, Bente Husby, Håkan Westberg
BACKGROUND: Occupational exposure to cobalt is well established in hard metal manufacture. Cobalt is known to cause contact allergy, asthma, hard metal lung disease, and lung cancer. The relationship between skin exposure and uptake determined in blood has not been extensively investigated. OBJECTIVE: To examine whether skin and inhalable air exposure to cobalt contributes to uptake, determined as cobalt in blood, in a hard metal manufacturing factory. METHODS: The amount of cobalt on the skin found with an acid wash technique, the air concentrations of inhalable cobalt and cobalt blood concentrations were determined and correlated in exposed workers...
July 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28672829/fexofenadine-suppresses-delayed-type-hypersensitivity-in-the-murine-model-of-palladium-allergy
#14
Ryota Matsubara, Kenichi Kumagai, Hiroaki Shigematsu, Kazutaka Kitaura, Yasunari Nakasone, Satsuki Suzuki, Yoshiki Hamada, Ryuji Suzuki
Palladium is frequently used in dental materials, and sometimes causes metal allergy. It has been suggested that the immune response by palladium-specific T cells may be responsible for the pathogenesis of delayed-type hypersensitivity in study of palladium allergic model mice. In the clinical setting, glucocorticoids and antihistamine drugs are commonly used for treatment of contact dermatitis. However, the precise mechanism of immune suppression in palladium allergy remains unknown. We investigated inhibition of the immune response in palladium allergic mice by administration of prednisolone as a glucocorticoid and fexofenadine hydrochloride as an antihistamine...
June 25, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28670256/contact-allergy-in-the-population-of-patients-with-chronic-inflammatory-dermatoses-and-contact-hypersensitivity-to-corticosteroids
#15
Marek Kot, Jarosław Bogaczewicz, Beata Kręcisz, Anna Woźniacka
INTRODUCTION: Clinical studies indicate that contact allergy to glucocorticosteroids (GCS) is not rare and has been increasingly reported over the past decade. Among the risk factors for developing contact hypersensitivity to topical corticosteroids, chronic inflammatory skin diseases and polyvalent contact allergy seem to be most important. AIM: To present the structure of contact allergy in the population of patients with chronic inflammatory dermatoses (CID) and contact hypersensitivity to corticosteroids...
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28657568/metal-hypersensitivity-after-knee-arthroplasty-fact-or-fiction
#16
Massimo Innocenti, Berti Vieri, Tommaso Melani, Tommaso Paoli, Christian Carulli
BACKGROUND AND AIM OF THE WORK: Hypersensitivity to metals in the general population has an incidence of about 15%, and in rising also for the higher number of joint replacements in the last decades. Total Knee Arthroplasty (TKA) represents the most performed orthopaedic procedure during last years, and it seems to be particularly associated with sensitization after surgery. On the other hand, there is a rising amount of patients with painful but well implanted and functioning TKAs: in certain cases, after the exclusion of the most frequent causes of failure, a condition of hypersensitivity may be found, and a revision with anallergic implants is mandatory...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28627111/european-surveillance-system-on-contact-allergies-essca-results-with-the-european-baseline-series-2013-14
#17
W Uter, J C Amario-Hita, A Balato, B Ballmer-Weber, A Bauer, A Belloni Fortina, A Bircher, M M U Chowdhury, S M Cooper, M Czarnecka-Operacz, A Dugonik, R Gallo, A Giménez-Arnau, J D Johansen, S M John, M Kieć-Świerczyńska, T Kmecl, B Kręcisz, F Larese Filon, V Mahler, M Pesonen, T Rustemeyer, A Sadowska-Przytocka, J Sánchez-Pérez, S Schliemann, M L Schuttelaar, D Simon, R Spiewak, S Valiukevičienė, E Weisshaar, I R White, S M Wilkinson
BACKGROUND: Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, new products or formulations and regulatory intervention, the spectrum of contact sensitization changes. OBJECTIVE: To evaluate the current spectrum of contact allergy to allergens present in the European baseline series (EBS) across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (ESSCA, www...
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28616704/metallic-ion-release-after-knee-prosthesis-implantation-a-prospective-study
#18
Adrien Lons, Sophie Putman, Gilles Pasquier, Henri Migaud, Elodie Drumez, Julien Girard
INTRODUCTION: Metal-on-metal (MoM) hip replacement bearings produce metallic ions that can cause health complications. Metallic release also occurs with other materials, but data on metallic ion levels after knee arthroplasty are sparse. We postulate that knee replacement generates elevating metallic ions (chromium (Cr), cobalt (Co) and titanium (Ti)) during the first year after implantation. PATIENTS AND METHODS: This ongoing prospective study included all patients who underwent the same type of knee arthroplasty between May and December 2013...
June 14, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28595206/transcatheter-closure-of-atrial-septal-defect-with-atrial-septal-occluder-in-a-patient-with-nickel-allergy
#19
Hasan Arı, Selma Arı, Ahmet Tütüncü, Alper Karakuş, Mehmet Melek
Presently described is transcatheter closure of atrial septal defect with atrial septal occluder (ASO) device in a patient with nickel allergy. Patients with metal allergy who will undergo nitinol device implantation should be tested for possible nickel hypersensitivity. ASO device and treatment strategy (percutaneous or surgical) should be selected according to allergy test result.
June 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28561797/trav7-2-02-expressing-cd8%C3%A2-%C2%BA-t-cells-are-responsible-for-palladium-allergy
#20
Yuri Takeda, Yoshiko Suto, Koyu Ito, Wataru Hashimoto, Tadashi Nishiya, Kyosuke Ueda, Takayuki Narushima, Tetsu Takahashi, Kouetsu Ogasawara
While metallic biomaterials have led to an improvement in the quality of life, metal allergies, especially to palladium (Pd), has caused a recent increase in allergic patients. Metal allergy is known to be a T cell-mediated delayed-type hypersensitivity (DTH); however, the pathogenic T cell subsets and the specific T cell receptor (TCR) have not been identified. Therefore, we attempted to identify the pathogenic T cells responsible for Pd allergy. We found that activating CD8⁺ T cells significantly increased and that the TRAV (TCRα variable) 7-2*02 chain skewed in Pd allergic mice...
May 31, 2017: International Journal of Molecular Sciences
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