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https://www.readbyqxmd.com/read/28334372/simulations-imaging-and-modeling-a-unique-theme-for-an-undergraduate-research-program-in-biomechanics
#1
Stephanie M George, Zachary J Domire
As the reliance on computational models to inform experiments and evaluate medical devices grows, the demand for students with modeling experience will grow. In this paper, we report on the three year experience of a National Science Foundation funded Research Experiences for Undergraduates (REU) based on the theme simulations, imaging, and modeling in biomechanics. While directly applicable to REU sites, our findings also apply to those creating other types of summer undergraduate research programs. The objective of the paper is to examine if a theme of simulations, imaging, and modeling will improve students' understanding of the important topic of modeling, provide an overall positive research experience, and provide an interdisciplinary experience...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28331353/undernutrition-and-associated-factors-among-24-36-month-old-children-in-slum-areas-of-bahir-dar-city-ethiopia
#2
Yeshalem Mulugeta Demilew, Dagninet Derebe Abie
BACKGROUND: This study aimed to assess undernutrition and associated factors among 24-36-month-old children in the slum areas of Bahir Dar city. METHODS: A community-based cross-sectional study was conducted among 480 children from May 1 to 26, 2015. The simple random sampling technique was used to select respondents. Data were collected using a structured interviewer-administered questionnaire. Statistical Package for Social Sciences version 20 was used for analysis...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28330369/energy-transfer-in-multi-collision-environments-an-experimental-test-of-theory-lih-10-2-in-h2-0-0
#3
Xiaoyan Shen, Shuyin Wang, Kang Dai, Yifan Shen, Anthony J McCaffery
We report separate experimental and theoretical studies of the equilibration of highly excited LiH (v = 10; J = 2) in H2 at 680 K. Experiments that follow the time evolution of state-to-state population transfer in multi-collision conditions with μs resolution were carried out by Shen and co-workers at Xinjiang University and East China Institute of Science and Technology. At the same time, theoretical computations on the relaxation of this gas mixture were undertaken by McCaffery and co-workers at Sussex University...
March 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28328937/efficient-occupancy-model-fitting-for-extensive-citizen-science-data
#4
Emily B Dennis, Byron J T Morgan, Stephen N Freeman, Martin S Ridout, Tom M Brereton, Richard Fox, Gary D Powney, David B Roy
Appropriate large-scale citizen-science data present important new opportunities for biodiversity modelling, due in part to the wide spatial coverage of information. Recently proposed occupancy modelling approaches naturally incorporate random effects in order to account for annual variation in the composition of sites surveyed. In turn this leads to Bayesian analysis and model fitting, which are typically extremely time consuming. Motivated by presence-only records of occurrence from the UK Butterflies for the New Millennium data base, we present an alternative approach, in which site variation is described in a standard way through logistic regression on relevant environmental covariates...
2017: PloS One
https://www.readbyqxmd.com/read/28328231/use-of-cell-phones-and-computers-for-health-promotion-and-tobacco-cessation-by-american-indian-college-students-in-montana
#5
Jo Ann W Dotson, Lonnie A Nelson, Sara L Young, Dedra Buchwald, John Roll
INTRODUCTION: Cell phones and personal computers have become popular mechanisms for delivering and monitoring health information and education, including the delivery of tobacco cessation education and support. Tobacco smoking is prevalent among American Indians (AIs) and Alaska Natives (ANs), with 26% AI/AN adult men smoking compared to 19% of Caucasian adult males and 22% of African American adult males. Smoking is even more prevalent in Northern Plains AI populations, with 42% of men <i>and</i> women reporting current smoking...
January 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28328018/abundance-correction-for-mass-discrimination-effects-in-polymer-mass-spectra
#6
Martin S Engler, Sarah Crotty, Markus J Barthel, Christian Pietsch, Ulrich S Schubert, Sebastian Böcker
RATIONALE: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) is frequently used to analyze homo- and copolymers, i.e. for computing copolymer fingerprints. However, the oligomer abundances are influenced by mass discrimination, i.e. mass- and composition-dependent ionization. We have developed a computational method to correct the abundance bias caused by the mass discrimination. METHODS: MALDI-TOFMS in combination with computational methods was used to investigate three random copolymers with different ratios of styrene and isoprene...
May 30, 2016: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28327935/science-in-the-cloud-sic-a-use-case-in-mri-connectomics
#7
Gregory Kiar, Krzysztof J Gorgolewski, Dean Kleissas, William Gray Roncal, Brian Litt, Brian Wandell, Russel A Poldrack, Martin Wiener, R Jacob Vogelstein, Randal Burns, Joshua T Vogelstein
Modern technologies are enabling scientists to collect extraordinary amounts of complex and sophisticated data across a huge range of scales like never before. With this onslaught of data, we can allow the focal point to shift from data collection to data analysis. Unfortunately, lack of standardized sharing mechanisms and practices often make reproducing or extending scientific results very difficult. With the creation of data organization structures and tools which drastically improve code portability, we now have the opportunity to design such a framework for communicating extensible scientific discoveries...
March 7, 2017: GigaScience
https://www.readbyqxmd.com/read/28327916/multilayer-modeling-and-analysis-of-human-brain-networks
#8
Manlio De Domenico
Understanding how the human brain is structured, and how its architecture is related to the function, is of paramount importance for a variety of applications, including, but not limited to, new ways to prevent, deal with and cure brain diseases, such as Alzheimer's or Parkinson's, and psychiatric disorders, such as Schizophrenia. The recent advances in structural and functional neuroimaging, together with the increasing attitude to interdisciplinary approaches involving computer science, mathematics and physics, are fostering interesting results from computational neuroscience, that are quite often based on the analysis of complex network representation of human brain...
February 6, 2017: GigaScience
https://www.readbyqxmd.com/read/28327698/accuracy-and-reliability-of-different-cone-beam-computed-tomography-cbct-devices-for-structural-analysis-of-alveolar-bone-in-comparison-with-multislice-ct-and-micro-ct
#9
Jeroen Van Dessel, Laura Ferreira Pinheiro Nicolielo, Yan Huang, Walter Coudyzer, Benjamin Salmon, Ivo Lambrichts, Reinhilde Jacobs
OBJECTIVE: The aim of this study was to assess whether cone beam computed tomography (CBCT) may be used for clinically reliable alveolar bone quality assessment in comparison to its clinical alternatives, multislice computed tomography and the gold standard (micro-CT). MATERIALS AND METHODS: Six dentate mandibular bone samples were scanned with seven CBCT devices (ProMax 3D Max, NewTom GiANO, Cranex 3D, 3D Accuitomo 170, Carestream 9300, Scanora 3D, I-CAT Next generation), one micro-CT scanner (SkyScan 1174) and one MSCT machine (Somatom Definition Flash) using two protocols (standard and high-resolution)...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28326513/manual-vs-computer-assisted-sperm-analysis-can-casa-replace-manual-assessment-of-human-semen-in-clinical-practice
#10
Joanna Talarczyk-Desole, Anna Berger, Grażyna Taszarek-Hauke, Jan Hauke, Leszek Pawelczyk, Piotr Jedrzejczak
OBJECTIVES: The aim of the study was to check the quality of computer-assisted sperm analysis (CASA) system in comparison to the reference manual method as well as standardization of the computer-assisted semen assessment. MATERIAL AND METHODS: The study was conducted between January and June 2015 at the Andrology Laboratory of the Division of Infertility and Reproductive Endocrinology, Poznań University of Medical Sciences, Poland. The study group consisted of 230 men who gave sperm samples for the first time in our center as part of an infertility investigation...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28325973/building-a-database-for-long-term-monitoring-of-benthic-macrofauna-in-the-pertuis-charentais-2004-2014
#11
Anne S Philippe, Christine Plumejeaud-Perreau, Jérôme Jourde, Philippe Pineau, Nicolas Lachaussée, Emmanuel Joyeux, Frédéric Corre, Philippe Delaporte, Pierrick Bocher
BACKGROUND: Long-term benthic monitoring is rewarding in terms of science, but labour-intensive, whether in the field, the laboratory, or behind the computer. Building and managing databases require multiple skills, including consistency over time as well as organisation via a systematic approach. Here, we introduce and share our spatially explicit benthic database, comprising 11 years of benthic data. It is the result of intensive benthic sampling that has been conducted on a regular grid (259 stations) covering the intertidal mudflats of the Pertuis-Charentais (Marennes-Oléron Bay and Aiguillon Bay)...
2017: Biodiversity Data Journal
https://www.readbyqxmd.com/read/28325441/a-review-of-fuzzy-cognitive-maps-in-medicine-taxonomy-methods-and-applications
#12
REVIEW
Abdollah Amirkhani, Elpiniki I Papageorgiou, Akram Mohseni, Mohammad R Mosavi
BACKGROUND AND OBJECTIVE: A high percentage of medical errors, committed because of physician's lack of experience, huge volume of data to be analyzed, and inaccessibility to medical records of previous patients, can be reduced using computer-aided techniques. Therefore, designing more efficient medical decision-support systems (MDSSs) to assist physicians in decision-making is crucially important. Through combining the properties of fuzzy logic and neural networks, fuzzy cognitive maps (FCMs) are among the latest, most efficient, and strongest artificial intelligence techniques for modeling complex systems...
April 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28323588/virtual-reality-applications-for-stress-management-training-in-the-military
#13
Federica Pallavicini, Luca Argenton, Nicola Toniazzi, Luciana Aceti, Fabrizia Mantovani
INTRODUCTION: Stress Management Training programs are increasingly being adopted in the military field for resilience empowerment and primary stress prevention. In the last several years, advanced technologies (virtual reality in particular) have been integrated in order to develop more innovative and effective stress training programs for military personnel, including soldiers, pilots, and other aircrew professionals. This systematic review describes experimental studies that have been conducted in recent years to test the effectiveness of virtual reality-based Stress Management Training programs developed for military personnel...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28322578/interview-with-amr-h-sawalha-epigenetics-and-autoimmunity
#14
Amr H Sawalha
Amr H Sawalha is Professor of Internal Medicine and Marvin and Betty Danto Research Professor of Connective Tissue Research at the University of Michigan, Department of Internal Medicine, Division of Rheumatology. He also holds faculty appointments at the Center for Computational Medicine and Bioinformatics and the Graduate Program in Immunology at the University of Michigan. He was recently appointed as Guest Professor at Central South University in Changsha, China. He received his medical degree from Jordan University of Science and Technology and completed his residency training in internal medicine at the University of Oklahoma Health Sciences Center, and his fellowship in rheumatology at the University of Michigan...
March 21, 2017: Epigenomics
https://www.readbyqxmd.com/read/28321440/neuronify-an-educational-simulator-for-neural-circuits
#15
Svenn-Arne Dragly, Milad Hobbi Mobarhan, Andreas Våvang Solbrå, Simen Tennøe, Anders Hafreager, Anders Malthe-Sørenssen, Marianne Fyhn, Torkel Hafting, Gaute T Einevoll
Educational software (apps) can improve science education by providing an interactive way of learning about complicated topics that are hard to explain with text and static illustrations. However, few educational apps are available for simulation of neural networks. Here, we describe an educational app, Neuronify, allowing the user to easily create and explore neural networks in a plug-and-play simulation environment. The user can pick network elements with adjustable parameters from a menu, i.e., synaptically connected neurons modelled as integrate-and-fire neurons and various stimulators (current sources, spike generators, visual, and touch) and recording devices (voltmeter, spike detector, and loudspeaker)...
March 2017: ENeuro
https://www.readbyqxmd.com/read/28320904/kinetics-of-low-temperature-transitions-and-a-reaction-rate-theory-from-non-equilibrium-distributions
#16
Vincenzo Aquilanti, Nayara Dantas Coutinho, Valter Henrique Carvalho-Silva
This article surveys the empirical information which originated both by laboratory experiments and by computational simulations, and expands previous understanding of the rates of chemical processes in the low-temperature range, where deviations from linearity of Arrhenius plots were revealed. The phenomenological two-parameter Arrhenius equation requires improvement for applications where interpolation or extrapolations are demanded in various areas of modern science. Based on Tolman's theorem, the dependence of the reciprocal of the apparent activation energy as a function of reciprocal absolute temperature permits the introduction of a deviation parameter d covering uniformly a variety of rate processes, from those where quantum mechanical tunnelling is significant and d < 0, to those where d > 0, corresponding to the Pareto-Tsallis statistical weights: these generalize the Boltzmann-Gibbs weight, which is recovered for d = 0...
April 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28318146/allen-newell-s-program-of-research-the-video-game-test
#17
Fernand Gobet
Newell (1973) argued that progress in psychology was slow because research focused on experiments trying to answer binary questions, such as serial versus parallel processing. In addition, not enough attention was paid to the strategies used by participants, and there was a lack of theories implemented as computer models offering sufficient precision for being tested rigorously. He proposed a three-headed research program: to develop computational models able to carry out the task they aimed to explain; to study one complex task in detail, such as chess; and to build computational models that can account for multiple tasks...
March 20, 2017: Topics in Cognitive Science
https://www.readbyqxmd.com/read/28302551/role-of-structural-bioinformatics-in-drug-discovery-by-computational-snp-analysis-a-proposed-protocol-for-analyzing-variation-at-the-protein-level
#18
REVIEW
David K Brown, Özlem Tastan Bishop
With the completion of the human genome project at the beginning of the 21st century, the biological sciences entered an unprecedented age of data generation, and made its first steps toward an era of personalized medicine. This abundance of sequence data has led to the proliferation of numerous sequence-based techniques for associating variation with disease, such as genome-wide association studies and candidate gene association studies. However, these statistical methods do not provide an understanding of the functional effects of variation...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28301747/single-cell-transcriptional-analysis
#19
Angela R Wu, Jianbin Wang, Aaron M Streets, Yanyi Huang
Despite being a relatively recent technological development, single-cell transcriptional analysis through high-throughput sequencing has already been used in hundreds of fruitful studies to make exciting new biological discoveries that would otherwise be challenging or even impossible. Consequently, this has fueled a virtuous cycle of even greater interest in the field and compelled development of further improved technical methodologies and approaches. Thanks to the combined efforts of the research community, including the fields of biochemistry and molecular biology, technology and instrumentation, data science, computational biology, and bioinformatics, the single-cell RNA-sequencing field is advancing at a pace that is both astounding and unprecedented...
March 16, 2017: Annual Review of Analytical Chemistry
https://www.readbyqxmd.com/read/28296725/preoperative-use-of-pregabalin-for-acute-pain-in-spine-surgery-a-meta-analysis-of-randomized-controlled-trials
#20
Hai-Liang Jiang, Shuang Huang, Jiang Song, Xiang Wang, Zhong-Shu Cao
BACKGROUND: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of pregabalin for pain management following spine surgery. METHODS: In September 2016, a systematic computer-based search was conducted in PubMed, EMBASE, Web of Science, and Cochrane Database of Systematic Reviews. RCTs of patients prepared for spine surgery that compared pregabalin with placebo were retrieved. The primary endpoint was the VAS score with rest or mobilization at 12 hours, 24 hours, and 48 hours and cumulative morphine consumption at 24 hours and 48 hours...
March 2017: Medicine (Baltimore)
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