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Out of hospital cardiac arrest

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https://www.readbyqxmd.com/read/28528323/c-graph-a-validated-scoring-system-for-early-stratification-of-neurologic-outcome-after-out-of-hospital-cardiac-arrest-treated-with-targeted-temperature-management
#1
Erich L Kiehl, Alex M Parker, Ralph M Matar, Matthew F Gottbrecht, Michelle C Johansen, Mark P Adams, Lori A Griffiths, Steven P Dunn, Katherine L Bidwell, Venu Menon, Kyle B Enfield, Lawrence W Gimple
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) results in significant morbidity and mortality, primarily from neurologic injury. Predicting neurologic outcome early post-OHCA remains difficult in patients receiving targeted temperature management. METHODS AND RESULTS: Retrospective analysis was performed on consecutive OHCA patients receiving targeted temperature management (32-34°C) for 24 hours at a tertiary-care center from 2008 to 2012 (development cohort, n=122)...
May 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28526668/north-american-public-opinion-survey-on-the-acceptability-of-crowdsourcing-basic-life-support-for-out-of-hospital-cardiac-arrest-with-the-pulsepoint-mobile-phone-app
#2
Katie N Dainty, Haris Vaid, Steven C Brooks
BACKGROUND: The PulsePoint Respond app is a novel system that can be implemented in emergency dispatch centers to crowdsource basic life support (BLS) for patients with cardiac arrest and facilitate bystander cardiopulmonary resuscitation (CPR) and automated external defibrillator use while first responders are en route. OBJECTIVE: The aim of this study was to conduct a North American survey to evaluate the public perception of the above-mentioned strategy, including acceptability and willingness to respond to alerts...
May 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28526495/automated-external-defibrillator-and-operator-performance-in-out-of-hospital-cardiac-arrest
#3
Jolande A Zijlstra, Loes E Bekkers, Michiel Hulleman, Stefanie G Beesems, Rudolph W Koster
AIM: An increasing number of failing automated external defibrillators (AEDs) is reported: AEDs not giving a shock or other malfunction. We assessed to what extent AEDs are 'failing' and whether this had a device-related or operator-related cause. METHODS: We studied analysis periods from AEDs used between January 2012 and December 2014. For each analysis period we assessed the correctness of the (no)-shock advice (sensitivity/specificity) and reasons for an incorrect (no)-shock advice...
May 16, 2017: Resuscitation
https://www.readbyqxmd.com/read/28506865/protocol-driven-neurological-prognostication-and-withdrawal-of-life-sustaining-therapy-after-cardiac-arrest-and-targeted-temperature-management
#4
Irina Dragancea, Matthew P Wise, Nawaf Al-Subaie, Julius Cranshaw, Hans Friberg, Guy Glover, Tommaso Pellis, Rebecca Rylance, Andrew Walden, Niklas Nielsen, Tobias Cronberg
BACKGROUND: Brain injury is reportedly the main cause of death for patients resuscitated after out-of-hospital cardiac arrest (OHCA). However, the majority may actually die following withdrawal of life-sustaining therapy (WLST) with a presumption of poor neurological recovery. We investigated how the protocol for neurological prognostication was used and how related treatment recommendations might have affected WLST decision-making and outcome after OHCA in the Targeted Temperature Management (TTM) trial...
May 12, 2017: Resuscitation
https://www.readbyqxmd.com/read/28502185/characteristics-management-and-results-of-out-of-hospital-cardiac-arrest-ohca-with-or-without-st-segment-elevation-myocardial-infarction-stemi
#5
Mary Beth Fisher, Adrian Messerli, Thomas F Whayne
No abstract text is available yet for this article.
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28497927/the-potential-role-of-pain-related-sseps-in-the-early-prognostication-of-long-term-functional-outcome-in-post-anoxic-coma
#6
Alessandra Del Felice, Stefano Bargellesi, Federico Linassi, Bruno Scarpa, Emanuela Formaggio, Paolo Boldrini, Stefano Masiero, Paolo Zanatta
BACKGROUND: Cardiac arrest (CA) is a common cause of disability. Multimodal evaluation has improved prognosis but precocious biomarkers are not appropriate in determining long-term functional outcome. AIM: to identify early prognostication markers of long-term functional outcome in post-anoxic coma. DESIGN: retrospective assessment of outcomes. POPULATION: Individuals older than 18 years with post-anoxic coma hospitalized in intensive care units after cardiac arrest (CA) regardless of cause (cardiac or non-cardiac) and location of event (in or out-of-hospital)...
May 12, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28497243/-kids-save-lives-resuscitation-training-for-schoolchildren-systematic-review
#7
D C Schroeder, H Ecker, S Wingen, F Semeraro, B W Böttiger
BACKGROUND: Even in western developed countries, the probability of survival after out-of-hospital cardiac arrest (OHCA) is only 6-10%. In order to improve survival after OHCA, early initiation of cardiopulmonary resuscitation (CPR) by laypersons is essential. Introduction of CPR training in schoolchildren seems to be effective to increase lay-CPR rates. OBJECTIVE: The objective of the present investigation was to elucidate educational aspects of teaching schoolchildren in CPR and to summarize campaigns related to a comprehensive establishment of lay-CPR worldwide...
May 11, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28493598/bystander-cpr-is-clustered-and-associated-with-neighborhood-socioeconomic-characteristics-a-geospatial-analysis-of-kent-county-michigan
#8
Amy Uber, Richard C Sadler, Todd Chassee, Joshua C Reynolds
OBJECTIVES: Geographic clustering of bystander CPR is associated with demographic and socioeconomic features of the community where out-of-hospital cardiac arrest (OHCA) occurred, though this association remains largely untested in rural areas. With a significant rural component and relative racial homogeneity, Kent County, Michigan provides a unique setting to externally validate or identify new community features associated with bystander CPR. Using a large, countywide dataset, we tested for geographic clustering of bystander CPR, and its associations with community socioeconomic features...
May 11, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28492570/-the-use-of-mechanical-chest-compression-devices-for-both-out-of-hospital-and-in-hospital-refractory-cardiac-arrest
#9
Alessandra Russo, Nicola Gasparetto, Luca Favero, Salvatore Ivan Caico, Silvia Orazio, Guido Garzena, Paolo Rosi, Zoran Olivari
The purpose of cardiopulmonary resuscitation after sudden cardiac arrest is to restore minimal blood flow to provide oxygen to the brain and other vital organs. Chest compressions and external defibrillation are the first line for circulatory support. Although early defibrillation is the main factor influencing survival, cardiopulmonary resuscitation must be characterized by high-quality external chest compressions. Unfortunately, the performance of manual chest compressions decreases during time and in hostile conditions...
April 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28490655/practice-guideline-summary-reducing-brain-injury-following-cardiopulmonary-resuscitation-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology
#10
Romergryko G Geocadin, Eelco Wijdicks, Melissa J Armstrong, Maxwell Damian, Stephan A Mayer, Joseph P Ornato, Alejandro Rabinstein, José I Suarez, Michel T Torbey, Richard M Dubinsky, Jason Lazarou
OBJECTIVE: To assess the evidence and make evidence-based recommendations for acute interventions to reduce brain injury in adult patients who are comatose after successful cardiopulmonary resuscitation. METHODS: Published literature from 1966 to August 29, 2016, was reviewed with evidence-based classification of relevant articles. RESULTS AND RECOMMENDATIONS: For patients who are comatose in whom the initial cardiac rhythm is either pulseless ventricular tachycardia (VT) or ventricular fibrillation (VF) after out-of-hospital cardiac arrest (OHCA), therapeutic hypothermia (TH; 32-34°C for 24 hours) is highly likely to be effective in improving functional neurologic outcome and survival compared with non-TH and should be offered (Level A)...
May 10, 2017: Neurology
https://www.readbyqxmd.com/read/28486897/effect-of-pre-hospital-advanced-airway-management-for-out-of-hospital-cardiac-arrest-caused-by-respiratory-disease-a-propensity-score-matched-study
#11
N Ohashi-Fukuda, T Fukuda, N Yahagi
Optimal pre-hospital care for out-of-hospital cardiac arrest (OHCA) caused by respiratory disease may differ from that for OHCA associated with other aetiologies, especially with respect to respiratory management. We aimed to investigate whether pre-hospital advanced airway management (AAM) was associated with favourable outcomes after OHCA caused by intrinsic respiratory disease. This nationwide, population-based, propensity score-matched study of adult patients in Japan with OHCA due to respiratory disease from 1 January 2005 to 31 December 2012 compared patients with and without pre-hospital AAM...
May 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28486696/coronary-artery-bypass-surgery-within-48%C3%A2-hours-after-cardiac-arrest-due-to-acute-myocardial-infarction
#12
Christina Grothusen, Christine Friedrich, Tim Attmann, Jette Meinert, Eva Ohnewald, Ulysses Ulbricht, Katharina Huenges, Assad Haneya, Derk Frank, Jan-Thorsten Graesner, Jan Schoettler, Jochen Cremer
OBJECTIVES: Cardiac arrest (CA) in patients with acute myocardial infarction is associated with a poor prognosis. Due to the additional trauma, risk of stroke and lack of data, coronary artery bypass grafting (CABG) is a controversial revascularization strategy for patients who cannot be treated percutaneously. Against this background, we investigated the outcome of patients from our department with acute myocardial infarction undergoing CABG after CA. METHODS: Between January 2001 and January 2015, 129 patients with preoperative CA due to acute myocardial infarction underwent CABG at our institution within 48 h after the CA had occurred...
May 8, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28483206/automated-external-defibrillators-and-survival-after-nonresidential-out-of-hospital-cardiac-arrest-in-a-small-north-american-city
#13
Anita Lwanga, Enrique Garcia-Sayan, Steven Lwanga, Erwin Karreman, Amira Mohamed
Most studies demonstrate that the use of automated external defibrillators (AEDs) during out of hospital cardiac arrest is associated with survival, but the majority of these studies were performed in large cities. With this in mind, the aims of our study were to examine AED placement and variables associated with survival after nonresidential out of hospital cardiac arrest (NROHCA) in a small North American city. Cases of NROHCA and locations with AEDs, in Regina, between January 2010 and December 2014 were reviewed...
March 29, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28482803/serum-neutrophil-gelatinase-associated-lipocalin-levels-predict-the-neurological-outcomes-of-out-of-hospital-cardiac-arrest-victims
#14
Tadashi Kaneko, Motoki Fujita, Yasuaki Ogino, Takahiro Yamamoto, Ryosuke Tsuruta, Shunji Kasaoka
BACKGROUND: Serum neutrophil gelatinase-associated lipocalin (NGAL) is a well-known biomarker of acute kidney injury. Serum NGAL was recently proposed as a potential predictor of mortality in post cardiac arrest syndrome (PCAS) patients following out-of-hospital cardiac arrest (OHCA). However, the potential predictive value of NGAL for neurological outcomes is unknown. Therefore, we assessed the potential predictive value of NGAL for neurological outcomes after OHCA. We also compared its predictive value with that of neuron-specific enolase (NSE) as an established biomarker...
May 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28476480/mortality-in-patients-resuscitated-from-out-of-hospital-cardiac-arrest-based-on-automated-blood-cell-count-and-neutrophil-lymphocyte-ratio-at-admission
#15
Christoph Weiser, Michael Schwameis, Fritz Sterz, Harald Herkner, Irene M Lang, Ilse Schwarzinger, Alexander O Spiel
INTRODUCTION: The neutrophil lymphocyte ratio(NLR) is a marker of systemic inflammation. We hypothesized that admission NLR is related to mortality and that epinephrine application during resuscitation influences NLR in patients after successful resuscitation from out of hospital cardiac arrest (OHCA). METHODS: This retrospective cohort study is based on a registry including all OHCA patients who had a presumed cardiac cause of cardiac arrest and achieved sustained ROSC prior to admission between 2005 and 2014...
May 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28476479/the-cost-effectiveness-of-a-mechanical-compression-device-in-out-of-hospital-cardiac-arrest
#16
Joachim Marti, Claire Hulme, Zenia Ferreira, Silviya Nikolova, Ranjit Lall, Charlotte Kaye, Michael Smyth, Charlotte Kelly, Tom Quinn, Simon Gates, Charles D Deakin, Gavin D Perkins
AIM: To assess the cost-effectiveness of LUCAS-2, a mechanical device for cardiopulmonary resuscitation (CPR) as compared to manual chest compressions in adults with non-traumatic, out-of-hospital cardiac arrest. METHODS: We analysed patient-level data from a large, pragmatic, multi-centre trial linked to administrative secondary care data from the Hospital Episode Statistics (HES) to measure healthcare resource use, costs and outcomes in both arms. A within-trial analysis using quality adjusted life years derived from the EQ-5D-3L was conducted at 12-month follow-up and results were extrapolated to the lifetime horizon using a decision-analytic model...
May 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28476474/the-association-between-aha-cpr-quality-guideline-compliance-and-clinical-outcomes-from-out-of-hospital-cardiac-arrest
#17
Sheldon Cheskes, Robert H Schmicker, Tom Rea, Laurie J Morrison, Brian Grunau, Ian R Drennan, Brian Leroux, Christian Vaillancourt, Terri A Schmidt, Allison C Koller, Peter Kudenchuk, Tom P Aufderheide, Heather Herren, Katharyn H Flickinger, Mark Charleston, Ron Straight, Jim Christenson
BACKGROUND: Measures of chest compression fraction (CCF), compression rate, compression depth and pre-shock pause have all been independently associated with improved outcomes from out-of-hospital (OHCA) cardiac arrest. However, it is unknown whether compliance with American Heart Association (AHA) guidelines incorporating all the aforementioned metrics, is associated with improved survival from OHCA. METHODS: We performed a secondary analysis of prospectively collected data from the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest database...
May 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28473275/effects-of-repeated-epinephrine-administration-and-administer-timing-on-witnessed-out-of-hospital-cardiac-arrest-patients
#18
R Sagisaka, H Tanaka, H Takyu, H Ueta, S Tanaka
BACKGROUND: Repeated administration of epinephrine is associated with unfavorable cerebral outcome after out-of-hospital cardiac arrests (OHCA), but the timing of epinephrine administration has not been considered. AIM: The aim of the study was to analyze the effects of repeated epinephrine administration after OHCA on favorable cerebral function coded by cerebral performance categories (CPC 1-2). METHODS: A nationwide, retrospective, population-based observational study was conducted by using Utstein-style data between 2010 and 2012 in Japan...
May 1, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28467879/bystander-efforts-and-1-year-outcomes-in-out-of-hospital-cardiac-arrest
#19
COMPARATIVE STUDY
Kristian Kragholm, Mads Wissenberg, Rikke N Mortensen, Steen M Hansen, Carolina Malta Hansen, Kristinn Thorsteinsson, Shahzleen Rajan, Freddy Lippert, Fredrik Folke, Gunnar Gislason, Lars Køber, Kirsten Fonager, Svend E Jensen, Thomas A Gerds, Christian Torp-Pedersen, Bodil S Rasmussen
BACKGROUND: The effect of bystander interventions on long-term functional outcomes among survivors of out-of-hospital cardiac arrest has not been extensively studied. METHODS: We linked nationwide data on out-of-hospital cardiac arrests in Denmark to functional outcome data and reported the 1-year risks of anoxic brain damage or nursing home admission and of death from any cause among patients who survived to day 30 after an out-of-hospital cardiac arrest. We analyzed risks according to whether bystander cardiopulmonary resuscitation (CPR) or defibrillation was performed and evaluated temporal changes in bystander interventions and outcomes...
May 4, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28467148/outcomes-of-cardiac-arrest-in-residential-care-homes-for-the-elderly-in-hong-kong
#20
Kit Ling Fan, Ling Pong Leung
OBJECTIVE: Studies done in the 1990's suggested nursing home residents with cardiac arrest had minimal chance of survival and resuscitation was not recommended. More recent studies showed opposing results. In Hong Kong, the proportion of elderly living in the residential care homes for the elderly is increasing. There is no study of out-of-hospital cardiac arrest outcomes in this population. This study aimed at evaluating the prognosis of out-of-hospital cardiac arrest occurring in the residential care homes for the elderly...
May 3, 2017: Prehospital Emergency Care
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