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https://www.readbyqxmd.com/read/29775316/l-arginine-catalyzed-synthesis-of-nanometric-organosilica-particles-through-a-waterborne-sol-gel-process-and-their-porous-structure-analysis
#1
Xiaoguang Qiao, Pierre-Yves Dugas, Laurent Veyre, Elodie Bourgeat-Lami
We report an efficient and easy to implement waterborne sol-gel process for the synthesis of nanometric organosilica particles. In this process, tetraethyl orthosilicate (TEOS) and 3-(methacryloxy)propyl trimethoxy silane (γ-MPS), employed as silica sources, are heterogeneously delivered in an aqueous solution of L-arginine, a basic amino acid used as catalyst, from a top organic layer. Co-condensation of TEOS with γ-MPS led to organosilica particles with diameters comprised between 30 and 230 nm when increasing the γ-MPS content from 0 to 10...
May 18, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29773369/cellulose-based-molecularly-imprinted-red-blood-cell-like-microparticles-for-the-selective-capture-of-cortisol
#2
Koichiro Hayashi, Hikaru Hayashi, Shota Yamada, Wataru Sakamoto, Toshinobu Yogo
Magnetite-nanoparticle-containing red-blood-cell-like-microparticles (M-RBC-MPs) with a selective ability for trapping cortisol (COR) were synthesized by an electrospray technique of a molecularly imprinted ethyl(hydroxyethyl) cellulose (EHEC)-based precursor. The as-synthezied M-RBC-MPs were ∼3-μm-disks with a dent. M-RBC-MPs contained magnetite nanoparticles below 15 nm in diameter, which exhibited magnetization and no room-temperature coercivity. The molecularly imprinted M-RBC-MPs (MI-M-RBC-MPs) passed through pores less than their diameter...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29767056/performance-and-ruminal-parameters-of-fattening-moghani-lambs-fed-recycled-poultry-bedding
#3
Ayoub Azizi, Afrooz Sharifi, Arash Azarfar, Ali Kiani, Alireza Jolazadeh
This study investigated the effects of recycled poultry bedding (RPB) on performance and protozoa population, microbial enzyme activity and microbial protein synthesis (MPS) in rumen contents of fattening lambs. Thirty-six male Moghani lambs (31.4 ± 3.2 kg body weight) were fed iso-energetic and iso-nitrogenous diets containing 0, 70, 140 or 210 g/kg dry matter (DM) RPB in a balanced randomized design (9 lambs per treatment). Results showed that final body weight, DM intake, average daily gain and feed conversion ratio were unchanged ( P  > 0...
June 2017: Animal nutrition
https://www.readbyqxmd.com/read/29755819/vitreoretinal-interface-characteristics-in-eyes-with-idiopathic-macular-holes-qualitative-and-quantitative-analysis
#4
Arzu Seyhan Karatepe, Jale Menteş, E Tansu Erakgün, Filiz Afrashi, Serhad Nalçacı, Cezmi Akkın, Yeşim Ateş
Objectives: To determine the qualitative and quantitative vitreoretinal interface characteristics with spectral domain optical coherence tomography (SD-OCT) in eyes with macular hole (MH) and investigate their relation with best corrected visual acuity (BCVA) and MH duration. Materials and Methods: Sixty-one eyes of 46 consecutive patients diagnosed with idiopathic MH were included in the study. The mean age of the patients was 66.7±7.5 (51-79) years. Complete ophthalmologic examination and SD-OCT examination were performed in all eyes and MH stages were determined according to SD-OCT findings...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29745033/role-of-teriparatide-in-glucocorticoid-induced-osteoporosis-through-regulating-cellular-reactive-oxygen-species
#5
Tao Wang, Chao Han, Peng Tian, Peng-Fei Li, Xin-Long Ma
OBJECTIVE: To determine the signaling pathways mediated by teriparatide in MLO-Y4 cell lines based on the evaluation of reactive oxygen species (ROS) through AKT pathways, which regulate apoptosis of bone cells. METHODS: We performed the DCFH-DA assay to investigate the role of ROS in MLO-Y4 cells caused by dexamethasone (Dex). Four groups were included: Dex group, Dex+NAC, Dex+ teriparatide group and control group (without any dispose). Real-time reverse transcriptase polymerase chain reaction was used to test the SOD2 and Cat mRNA expression...
May 10, 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29735373/natural-history-of-echocardiographic-abnormalities-in-mucopolysaccharidosis-iii
#6
Carolyn M Wilhelm, Kristen V Truxal, Kim L McBride, John P Kovalchin, Kevin M Flanigan
BACKGROUND: Mucopolysaccharidosis (MPS) type III, Sanfilippo Syndrome, is an autosomal recessive lysosomal storage disorder. MPS I and II patients often develop cardiac involvement leading to early mortality, however there are limited data in MPS III. The objective of this study is to describe cardiac abnormalities in a large group of MPS III patients followed in a longitudinal natural history study designed to determine outcome measures for gene transfer trials. METHODS: A single center study of MPS III patients who were enrolled in the Nationwide Children's Hospital natural history study in 2014...
April 27, 2018: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29735104/inhibition-of-interaction-between-epigallocatechin-3-gallate-and-myofibrillar-protein-by-cyclodextrin-derivatives-improves-gel-quality-under-oxidative-stress
#7
Yumeng Zhang, Lin Chen, Yuanqi Lv, Shuangxi Wang, Zhiyao Suo, Xingguang Cheng, Xinglian Xu, Guanghong Zhou, Zhixi Li, Xianchao Feng
High levels of polyphenols can interact with myofibrillar proteins (MPs), causing damage to a MP emulsion gel. In this study, β-cyclodextrins were used to reduce covalent and non-covalent interaction between epigallocatechin-3-gallate (EGCG) and MPs under oxidative stress. The loss of both thiol and free amine groups and the unfolding of MPs caused by EGCG (80 μM/g protein) were significantly prevented by β-cyclodextrins, and the structural stability and solubility were improved. MP emulsion gel treated with EGCG (80 μM/g protein) had the highest cooking loss (68...
June 2018: Food Research International
https://www.readbyqxmd.com/read/29728280/intensification-of-uv-c-tertiary-treatment-disinfection-and-removal-of-micropollutants-by-sulfate-radical-based-advanced-oxidation-processes
#8
J Rodríguez-Chueca, C García-Cañibano, R-J Lepistö, Á Encinas, J Pellinen, J Marugán
This study explores the enhancement of UV-C tertiary treatment by sulfate radical based Advanced Oxidation Processes (SR-AOPs), including photolytic activation of peroxymonosulfate (PMS) and persulfate (PS) and their photocatalytic activation using Fe(II). Their efficiency was assessed both for the inactivation of microorganisms and the removal or micropollutants (MPs) in real wastewater treatment plant effluents. Under the studied experimental range (UV-C dose 5.7-57 J/L; UV-C contact time 3 to 28 s), the photolysis of PMS and PS (0...
April 21, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29715125/safety-and-feasibility-of-single-port-surgery-for-colon-cancer-in-octogenarians
#9
Mitsuyoshi Tei, Masahisa Otsuka, Yozo Suzuki, Kentaro Kishi, Masahiro Tanemura, Hiroki Akamatsu
BACKGROUND/AIM: The use of single-port surgery (SPS) in elderly patients with colon cancer remains controversial. The aim of this study was to evaluate the clinical outcomes of elderly patients who underwent SPS. PATIENTS AND METHODS: Consecutive patients >80 years old of age who underwent SPS (n=86) or multi-port surgery (MPS) (n=40) for colon cancer from January 2008 to December 2014 were analyzed. Short-term and long-term outcomes were compared between groups...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29707013/the-effect-of-resection-angle-on-stress-distribution-after-root-end-surgery
#10
Jaiane Bandoli Monteiro, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Alexandre Luiz Souto Borges, Rubens Nisie Tango
Introduction: This study aimed to investigate the influence of the resection angle on the stress distribution of retrograde endodontic treated maxillary incisors under oblique-load application. Methods and Materials: A maxillary central incisor which was endodontically treated and restored with a fiber glass post was obtained in a 3-dimensional numerical model and distributed into three groups according to type of resection: control; restored with fiber post without retrograde obturation, R45 and R90 with 45º and 90º resection from tooth axial axis, respectively and restored with Fuji II LC (GC America)...
2018: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/29706403/facile-preparation-of-an-alternating-copolymer-based-high-molecular-shape-selective-organic-phase-for-reversed-phase-liquid-chromatography
#11
Abul K Mallik, Hiroki Noguchi, Mohammed Mizanur Rahman, Makoto Takafuji, Hirotaka Ihara
The synthesis of a new alternating copolymer-grafted silica phase is described for the separation of shape-constrained isomers of polycyclic aromatic hydrocarbons (PAHs) and tocopherols in reversed-phase high-performance liquid chromatography (RP-HPLC). Telomerization of the monomers (octadecyl acrylate and N-methylmaleimide) was carried out with a silane coupling agent; 3-mercaptopropyltrimethoxysilane (MPS), and the telomer (T) was grafted onto porous silica surface to prepare the alternating copolymer-grafted silica phase (Sil-alt-T)...
April 23, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29705972/p-tau-and-subunit-c-mitochondrial-atp-synthase-accumulation-in-the-central-nervous-system-of-a-woman-with-hurler-scheie-syndrome-treated-with-enzyme-replacement-therapy-for-12-years
#12
Hiroshi Kobayashi, Masamichi Ariga, Yohei Sato, Masako Fujiwara, Nei Fukasawa, Takahiro Fukuda, Hiroyuki Takahashi, Masahiro Ikegami, Motomichi Kosuga, Torayuki Okuyama, Yoshikatsu Eto, Hiroyuki Ida
We report an autopsy case of a woman with mucopolysaccharidosis type I (MPS I) Hurler-Scheie syndrome who was treated with enzyme replacement therapy (ERT) for 12 years. This was the first case of MPS I treated with ERT in Japan. Pathological analysis showed no glycosaminoglycan accumulation in the liver and spleen as a result of long-term ERT, although severe aortic stenosis, diffuse intimal hyperplasia of the coronary artery, and fibrous hypertrophy of the endocardium were observed. Additionally, we detected subunit c mitochondrial ATP synthase (SCMAS) accumulation and mild tauopathy (hyperphosphorylated tau or p-tau, both 3-repeat and 4-repeat tau accumulation) in the same area of the cerebral limbic system and central gray matter of the mid brain and pons...
April 29, 2018: JIMD Reports
https://www.readbyqxmd.com/read/29705420/short-communication-in-vitro-rumen-gas-production-and-starch-degradation-of-starch-based-feeds-depend-on-mean-particle-size
#13
A Gallo, G Giuberti, A S Atzori, F Masoero
Our objective was to model the effect of mean particle size (mPS) on in vitro rumen starch degradation (IVSD) and the kinetics of gas production for different starch-based feeds. For each feed, 2 batches of the same grains were separately processed through 2 different mills (cutter or rotor speed mills), with or without different screens to achieve a wide range of mPS (0.32 to 3.31 mm for corn meals; 0.19 to 2.81 mm for barley meals; 0.16 to 2.13 mm for wheat meals; 0.28 to 2.32 mm for oat meals; 0.21 to 2...
April 25, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29702726/moss-protonemata-are-dispersed-by-water-wind-and-snails
#14
Carlos J Pasiche-Lisboa, Inés Sastre-De Jesús
PREMISE OF THE STUDY: Mosses produce asexual propagules, which are dispersed, thus allowing population establishment and maintenance. However, it is unknown if or how protonemata-one of their asexually produced propagules-are dispersed. Moss protonemata were exposed to three dispersal vectors (water, wind, and snails) to describe the dispersal capability and survival after dispersal. METHODS: The protonemata of mosses Callicostella belangeriana and Taxiphyllum taxirameum were splashed with water drops from a 1 or 2 m height, exposed to two wind velocities (V1 = 2...
April 27, 2018: American Journal of Botany
https://www.readbyqxmd.com/read/29700418/smarca4-deficient-undifferentiated-uterine-sarcoma-malignant-rhabdoid-tumor-of-the-uterus-a-clinicopathologic-entity-distinct-from-undifferentiated-carcinoma
#15
David L Kolin, Fei Dong, Michele Baltay, Neal Lindeman, Laura MacConaill, Marisa R Nucci, Christopher P Crum, Brooke E Howitt
Small cell carcinoma of the ovary, hypercalcemic type is a rare, aggressive malignancy which usually occurs in young women and is characterized by mutations in SMARCA4, with few other alterations. We recently encountered uterine tumors with morphologic, immunohistochemical, and genetic similarities to small cell carcinoma of the ovary, hypercalcemic type. Herein we report the clinicopathologic and molecular features (using a targeted massively parallel sequencing [MPS] assay) of these tumors. The cases were diagnosed on cervical and endometrial biopsies (n = 2, 34, and 29 years) or hysterectomy and bilateral salpingo-oophorectomy (n = 3, 25, 33, and 58 years)...
April 26, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29683519/children-with-mucopolysaccharidosis-risk-progressive-visual-dysfunction-despite-haematopoietic-stem-cell-transplants
#16
Kristina Teär Fahnehjelm, Monica Olsson, Enping Chen, Jürg Hengstler, Karin Naess, Jacek Winiarski
AIM: This prospective study assessed the long-term ocular and visual outcomes of children with mucopolysaccharidoses type I Hurler syndrome (MPS IH) who were treated with haematopoietic stem cell transplants (HSCT). METHODS: Clinical ophthalmological assessments were performed on eight patients at the St Erik Eye Hospital, Stockholm, Sweden, from 2001-2018: The median age at diagnosis and HSCT were 12.2 (range 5.0-16.4) and 16.7 (8.0-20.4) months. The last eye examination was at a median of 13...
April 23, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29671225/effectiveness-of-early-hematopoietic-stem-cell-transplantation-in-preventing-neurocognitive-decline-in-mucopolysaccharidosis-type-ii-a-case-series
#17
A Selvanathan, C Ellaway, C Wilson, P Owens, P J Shaw, K Bhattacharya
The early progressive form of the X-linked disorder, Hunter syndrome or mucopolysaccharidosis type II (MPS II) (OMIM #309900), is characterized by cognitive decline, and pulmonary and cardiac complications that often cause death before 20 years of age. Deficiency of the lysosomal enzyme, iduronate-2-sulfatase (EC 3.1.6.13) results in deposition of the glycosaminoglycans, dermatan, and heparan sulfate in various tissues. In recent years, enzyme replacement therapy (ERT) has become the mainstay of treatment, but is expensive and ineffective in arresting cognitive decline...
April 19, 2018: JIMD Reports
https://www.readbyqxmd.com/read/29662787/steroid-associated-osteonecrosis-animal-model-in-rats
#18
Li-Zhen Zheng, Jia-Li Wang, Ling Kong, Le Huang, Li Tian, Qian-Qian Pang, Xin-Luan Wang, Ling Qin
Objective: Established preclinical disease models are essential for not only studying aetiology and/or pathophysiology of the relevant diseases but more importantly also for testing prevention and/or treatment concept(s). The present study proposed and established a detailed induction and assessment protocol for a unique and cost-effective preclinical steroid-associated osteonecrosis (SAON) in rats with pulsed injections of lipopolysaccharide (LPS) and methylprednisolone (MPS). Methods: Sixteen 24-week-old male Sprague-Dawley rats were used to induce SAON by one intravenous injection of LPS (0...
April 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29626345/the-personalities-of-danish-mps-trait-and-aspect-level-differences
#19
Asbjørn Sonne Nørgaard, Robert Klemmensen
OBJECTIVE: To study personality traits of Danish parliamentarians (MPs) and examine elite-voter congruence and elite differentiation. Whereas previous political elite studies have focused only on the Big Five level we include aspect-level differences. METHOD: In a highly representative survey of Danish MPs (N=81, response rate= 46.3 pct.) and a representative study of Danish voters (N=3,612) we used the 60-item NEO-PI-R short version to examine personality differences on the Big Five level and, based on the NEO-BFAS, the aspect level...
April 6, 2018: Journal of Personality
https://www.readbyqxmd.com/read/29604577/low-levels-of-microplastics-mp-in-wild-mussels-indicate-that-mp-ingestion-by-humans-is-minimal-compared-to-exposure-via-household-fibres-fallout-during-a-meal
#20
Ana I Catarino, Valeria Macchia, William G Sanderson, Richard C Thompson, Theodore B Henry
Microplastics (MPs) are the most numerous debris reported in marine environments and assessment of the amounts of MPs that accumulate in wild organisms is necessary for risk assessment. Our objective was to assess MP contamination in mussels collected around the coast of Scotland (UK) to identify characteristics of MPs and to evaluate risk of human exposure to MPs via ingestion of mussels. We deployed caged mussels (Mytilus edulis) in an urbanised estuary (Edinburgh, UK) to assess seasonal changes in plastic pollution, and collected mussels (Mytilus spp and subtidal Modiolus modiolus) from eight sampling stations around Scotland to enumerate MP types at different locations...
March 28, 2018: Environmental Pollution
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