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https://www.readbyqxmd.com/read/28432676/bifidobacterium-adolescentis-dsm-20083-and-lactobacillus-casei-lafti-l26-dsl-probiotics-able-to-block-the-in-vitro-adherence-of-rotavirus-in-ma104-cells
#1
Karem Prunella Fernandez-Duarte, Nury Nathalia Olaya-Galán, Sandra Patricia Salas-Cárdenas, Jazmin Lopez-Rozo, Maria Fernanda Gutierrez-Fernandez
Rotavirus is the leading worldwide cause of gastroenteritis in children under five years of age. Even though there are some available vaccines to prevent the disease, there are limited strategies for challenging diarrhea induced by rotavirus infection. For this reason, researchers are constantly searching for other approaches to control diarrhea by means of probiotics. In order to demonstrate the ability of some probiotic bacteria to interfere with the in vitro rotavirus infection in MA104 cells, strains of Lactobacillus sp...
April 21, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28430997/global-impact-of-rotavirus-vaccination-on-childhood-hospitalizations-and-mortality-from-diarrhea
#2
Eleanor Burnett, Christine L Jonesteller, Jacqueline E Tate, Catherine Yen, Umesh D Parashar
In 2006, two rotavirus vaccines were licensed. We summarize the impact of rotavirus vaccination on hospitalizations and deaths from rotavirus and all-cause acute gastroenteritis (AGE) during the first 10 years since vaccine licensure, including recent evidence from high child mortality countries. We used standardized guidelines (PRISMA) guidelines to identify observational evaluations of rotavirus vaccine impact among children <5 years of age that presented at least 12 months of pre- and post-vaccine introduction surveillance data...
April 18, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28425908/rotavirus-vaccine-breastfeeding-and-other-factors-that-could-affect-susceptibility-to-gastroenteritis-in-young-children
#3
Amy Elizabeth Murphy
No abstract available.
April 20, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28422995/characterization-of-rotavirus-infection-in-children-with-acute-gastroenteritis-in-bengo-province-northwestern-angola-prior-to-vaccine-introduction
#4
Carolina Gasparinho, João Piedade, Maria Clara Mirante, Cristina Mendes, Carlos Mayer, Susana Vaz Nery, Miguel Brito, Claudia Istrate
BACKGROUND: Rotavirus group A (RVA) is considered the leading cause of pediatric diarrhea, responsible for the high burden of diarrheal diseases in sub-Saharan Africa. Despite recent studies, the existent data are scarce for some African countries like Angola, a country with one of the highest RVA-related death estimates. The aim of this study was to determine the RVA detection rate and circulating genotypes in children less than five years of age with acute gastroenteritis attended at the Bengo General Hospital in Caxito, Bengo province, Angola, before vaccine introduction...
2017: PloS One
https://www.readbyqxmd.com/read/28419538/receiving-early-information-and-trusting-swedish-child-health-centre-nurses-increased-parents-willingness-to-vaccinate-against-rotavirus-infections
#5
Lina Schollin Ask, Anders Hjern, Ann Lindstrand, Ola Olen, Eva Sjögren, Margareta Blennow, Åke Örtqvist
AIM: Rotavirus vaccines are effective against severe infections, but have a modest impact on mortality in high-income countries. Parental knowledge and attitudes towards vaccines are crucial for high vaccination coverage. This study aimed to identify why parents refused to let their infant have the vaccination or were unsure. METHODS: This cross-sectional study was based on 1,063 questionnaires completed by the parents of newborn children in 2014. Stepwise logistic regression was used to identify the main predictors...
April 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28419020/education-in-the-waiting-room-description-of-a-pediatric-emergency-department-educational-initiative
#6
Sarah Reid, Gina Neto, Sandy Tse, Ken J Farion, Ariyan Marvizi, Lauren Smith, Chantalle Clarkin, Kristina Rohde, Katherine Moreau
OBJECTIVE: The aim of this study was to understand parents' awareness of and reactions to a slide presentation based waiting-room educational initiative. METHODS: This was a prospective observational study at a Canadian tertiary-care pediatric emergency department (ED) with an annual census of 68,000 visits. An anonymous parental survey was developed de novo, and parents were asked to complete the survey during their low-acuity ED visit over a 2-week study period...
April 18, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28416428/-nasogastric-rehydration-for-treating-children-with-gastroenteritis
#7
B Rébeillé-Borgella, C Barbier, R Moussaoui, A Faisant, A-P Michard-Lenoir, A Rubio
INTRODUCTION: When oral rehydration is not feasible, enteral rehydration via the nasogastric route has been the ESPGHAN recommended method of rehydration since 2008, rather than intravenous rehydration (IVR), for children with acute gastroenteritis. However, these recommendations are rarely followed in France. Since 2011, in case of failure of oral rehydration, enteral rehydration has been used as a first-line therapy in the Children's Emergency Department at the Grenoble-Alpes University Hospital...
April 14, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28403085/is-rotavirus-still-a-major-cause-for-diarrheal-illness-in-hospitalized-pediatric-patients-after-rotavirus-vaccine-introduction-in-the-saudi-national-immunization-program
#8
Moustafa Abdelaal Hegazi, Mohamed Hesham Sayed, Haifa Hasan Sindi, Osama Elsayed Bekhit, Basem Salama El-Deek, Faisal M Yaqoub Alshoudri, Amroo Khaled Noorelahi
Previous studies in Jeddah, western Saudi Arabia, showed rotavirus (RV) prevalence around 40% in pediatric inpatients with gastroenteritis (GE) with a maximum level during cooler months. Currently, there are no data on impact of rotavirus vaccine (RVV) on RV-GE in Saudi Arabia. Therefore, this study was conducted to assess impact of RVV on incidence and severity of RV-GE in hospitalized pediatric patients; 3 years after introduction of RVV in Saudi immunization program (SIP) in January, 2013.This cross-sectional observational study included GE cases under 5 years of age admitted to 2 tertiary hospitals, in Jeddah, from October to December, 2015...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28400860/multiple-etiologies-of-infectious-diarrhea-and-concurrent-infections-in-a-pediatric-outpatient-based-screening-study-in-odisha-india
#9
Arpit Kumar Shrivastava, Subrat Kumar, Nirmal Kumar Mohakud, Mrutyunjay Suar, Priyadarshi Soumyaranjan Sahu
BACKGROUND: There are multiple etiologies responsible for infectious gastroenteritis causing acute diarrhea which are often under diagnosed. Also acute diarrhea is one of the major causes of morbidity and mortality among children less than 5 years of age. METHODS: In our study, fecal samples (n = 130) were collected from children (<5 years) presenting with symptoms of acute diarrhea. Samples were screened for viral, bacterial, and parasitic etiologies. Rotavirus and Adenovirus were screened by immunochromatographic tests...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28399824/long-term-impact-of-self-financed-rotavirus-vaccines-on-rotavirus-associated-hospitalizations-and-costs-in-the-valencia-region-spain
#10
Alejandro Orrico-Sanchez, Mónica López-Lacort, Silvia Pérez-Vilar, Javier Díez-Domingo
BACKGROUND: Rotavirus vaccines are available in Spain from 2007. They are recommended by the Spanish Pediatric Association, but not funded by the National Health System (NHS) and its coverage rate reached 40-50%. The hospitalization rate reduction of rotavirus caused gastroenteritis (RVAGE) directly attributable to vaccination remains unclear due to the large differences described in published studies, ranging from 14 to 44.5% in children <5 years of age, even with similar vaccination coverage...
April 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28397879/intestinal-microbiome-in-children-with-severe-and-complicated-acute-viral-gastroenteritis
#11
Shih-Yen Chen, Chi-Neu Tsai, Yun-Shien Lee, Chun-Yuan Lin, Kuan-Yeh Huang, Hsun-Ching Chao, Ming-Wei Lai, Cheng-Hsun Chiu
The aim of the present study was to evaluate the microbiota of children with severe or complicated acute viral gastroenteritis (AGE). To that end, next-generation sequencing (NGS) technology was used to sequence the 16S ribosomal RNA (16S rRNA) gene in 20 hospitalized pediatric patients with severe or complicated AGE and a further 20 otherwise healthy children; the fecal microbiome was then assessed. Comparative metagenomics data were analyzed by a Wilcoxon rank-sum test and hierarchical clustering analysis of bacterial reads...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28397614/genotype-analysis-of-noroviruses-associated-with-gastroenteritis-outbreaks-in-childcare-centres-victoria-australia-2012-2015
#12
L D Bruggink, J M Moselen, J A Marshall
The characteristics of norovirus outbreaks in children (0-5 years) in childcare centres in Victoria, Australia (2012-2015) were examined. The three most common open reading frame (ORF) 2 genotypes in childcare centre outbreaks were GII.4 (42%), GII.6 (21%) and GII.3 (14%); the remaining genotypes (GI.2, GI.3, GI.4, GI.8, GI.13, GII.1, GII.2, GII.7 and GII.13) each made up <10%. The GII.4 genotype was the only norovirus genotype seen in all 4 years of the study and was the most common genotype in 2012-2014 but in 2015 the most common genotype was GII...
April 11, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28392538/listeria-monocytogenes-meningitis-complicating-rotavirus-gastroenteritis-in-an-immunocompetent-child
#13
Takuma Ohnishi, Akiko Kawano, Mayumi Araki, Yuko Hamahata, Machiko Usui, Motoko Shimoyamada, Takuya Tamame, Masayuki Akashi, Seiji Sato
Listeria monocytogenes only occasionally causes bacterial meningitis in immunocompetent children. We report a case of L. monocytogenes meningitis associated with rotavirus gastroenteritis. The patient was a previously healthy 20-month-old girl who was admitted because of sustained fever and lethargy after suffering from gastroenteritis for 6 days. The patient's peripheral white blood cell count was 18,600/µL and the C-reactive protein level was 2.44 mg/dL. A stool sample tested positive for rotavirus antigen...
April 7, 2017: Keio Journal of Medicine
https://www.readbyqxmd.com/read/28388889/molecular-epidemiology-of-rotavirus-causing-diarrhea-among-children-less-than-five-years-of-age-visiting-national-level-children-hospitals-nepal
#14
Subhash Dhital, Jeevan Bahadur Sherchand, Bharat Mani Pokhrel, Keshab Parajuli, Niranjan Shah, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sundar Khadka, Sulochana Khatiwada, Narayan Parajuli, Basistha Rijal
BACKGROUND: Rotaviruses are the major cause of diarrhea among the infants and young children all over the world causing over 500,000 deaths and 2.4 million hospitalizations each year. In Nepal Rotavirus infection positivity rates ranges from 17.0 to 39.0% among children less than 5 years. However, little is known about the molecular genotypes of Rotavirus prevailing. The objective of this study was to estimate the burden of Rotavirus gastroenteritis and determine the genotypes of Rotavirus among children less than 5 years...
April 7, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28381569/group-a-rotaviruses-in-chinese-bats-genetic-composition-serology-and-evidence-for-bat-to-human-transmission-and-reassortment
#15
Biao He, Xiaohong Huang, Fuqiang Zhang, Weilong Tan, Jelle Matthijnssens, Shaomin Qin, Lin Xu, Zihan Zhao, Ling'en Yang, Quanxi Wang, Tingsong Hu, Xiaolei Bao, Jianmin Wu, Changchun Tu
Bats are natural reservoirs for many pathogenic viruses and increasing evidence supports that bats can also harbor group A rotaviruses (RVA), important causative agents of diarrhea in children and young animals. Currently, 8 RVA strains have been identified from African and Chinese bats, possessing completely novel genotype constellations or genotypes possibly originating from other mammals. However, all these data were mainly based on detection of RVA RNA, only present during acute infections, which does not permit assessment of the true exposure of a bat population to RVA...
April 5, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28367780/impact-of-self-financed-rotavirus-vaccines-on-hospital-stays-and-costs-in-spain-after-a-3-year-introductory-period
#16
O Redondo-González, J M Tenías-Burillo, J Ruiz-Gonzalo
Vaccination has reduced rotavirus hospitalizations by 25% in European regions with low-moderate vaccine availability. We aimed to quantify the reduction in hospital costs after the longest period in which Rotarix® and Rotateq® were simultaneously commercially available in Spain. Cases, length of stay (LOS), and diagnosis-related groups (DRGs) were retrieved from the Minimum Basic Data Set. Healthcare expenditure was estimated through the cost accounting system Gescot®. DRGs were clustered: I, non-bacterial gastroenteritis with complications; II, without complications; III, requiring surgical/other procedures or neonatal cases (highest DRG weights)...
April 3, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28365283/-epidemiological-and-clinical-characteristics-of-infants-admitted-to-hospital-due-to-human-parechovirus-infections-a-prospective-study-in-spain
#17
Fernando Martín Del Valle, Cristina Calvo, Inés Martinez-Rienda, Amaia Cilla, María P Romero, Ana Isabel Menasalvas, Leticia Reis-Iglesias, Diana Roda, María J Pena, Nuria Rabella, María Del Mar Portugués de la Red, Gregoria Megías, Antonio Moreno-Docón, Almudena Otero, María Cabrerizo
INTRODUCTION: Human parechovirus (HPeV) is one of the recently described picornaviridae viruses that have been associated with fever of unknown origin (FUO), clinical sepsis, gastroenteritis, meningitis, or encephalitis in very young infants. The aim of this study is to describe the epidemiology and clinical features of these viruses. PATIENTS AND METHODS: A prospective multicentre 3-year study was conducted in 12 hospitals in Spain. Out of 850 specimens examined, 47 were positive (5...
March 29, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28363627/evaluation-of-a-nurse-initiated-acute-gastroenteritis-pathway-in-the-pediatric-emergency-department
#18
Rebecca A Carson, Shawna S Mudd, P Jamil Madati
Acute gastroenteritis (AGE) is a common illness treated in the emergency department. Delays in initiating rehydration for children with mild or moderate dehydration from AGE can lead to prolonged ED visits and increased resource utilization that do not provide prognostic value or support family-centered care. The purpose of this quality improvement project was to promote early oral rehydration therapy (ORT) for persons with AGE in an attempt to reduce unnecessary resource utilization and length of stay (LOS)...
March 28, 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/28360258/impact-of-maternal-antibodies-and-infant-gut-microbiota-on-the-immunogenicity-of-rotavirus-vaccines-in-african-indian-and-european-infants-protocol-for-a-prospective-cohort-study
#19
Kuladaipalayam Natarajan C Sindhu, Nigel Cunliffe, Matthew Peak, Mark Turner, Alistair Darby, Nicholas Grassly, Melita Gordon, Queen Dube, Sudhir Babji, Ira Praharaj, Valsan Verghese, Miren Iturriza-Gómara, Gagandeep Kang
INTRODUCTION: Gastroenteritis is the leading cause of morbidity and mortality among young children living in resource-poor settings, majority of which is attributed to rotavirus. Rotavirus vaccination can therefore have a significant impact on infant mortality. However, rotavirus vaccine efficacy in Sub-Saharan Africa and Southeast Asia is significantly lower than in high-income countries. Maternally derived antibodies, infant gut microbiota and concomitant oral polio vaccination have been proposed as potential reasons for poor vaccine performance in low-income settings...
March 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28359707/evidence-based-practice-video-discharge-instructions-in-the-pediatric-emergency-department
#20
Elyssa B Wood, Gina Harrison, Amber Trickey, Mary Ann Friesen, Sarah Stinson, Erin Rovelli, Serena McReynolds, Kristina Presgrave
While a high quality discharge from a Pediatric Emergency Department helps caregivers feel informed and prepared to care for their sick child at home, poor adherence to discharge instructions leads to unnecessary return visits, negative health outcomes, and decreased patient satisfaction. Nurses at the Inova Loudoun Pediatric ED utilized the Johns Hopkins Model of Evidence Based Practice to answer the following question: Among caregivers who have children discharged from the ED, does the addition of video discharge instructions (VDI) to standard written/verbal discharge instructions (SDI) result in improved knowledge about the child's diagnosis, treatment, illness duration, and when to seek further medical care? METHODS: A multidisciplinary team reviewed available evidence and created VDI for three common pediatric diagnoses: gastroenteritis, bronchiolitis, and fever...
March 28, 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
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