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https://www.readbyqxmd.com/read/28528378/trabeculotomy-opening-size-and-iop-reduction-after-trabectome%C3%A2-surgery
#1
Thomas Wecker, Alexandra Anton, Matthias Neuburger, Jens F Jordan, Christian van Oterendorp
BACKGROUND: Trabeculotomy with the Trabectome® is an effective surgical procedure to lower intraocular pressure (IOP). However, in some patients it does not lead to a significant IOP reduction despite a gonioscopically well visible opening of Schlemm's canal. This study investigated whether the size of the trabeculotomy opening and other parameters, including anterior chamber depth (ACD) are related to IOP reduction. METHODS: Retrospective observational case series with 93 eyes of 93 patients who underwent Trabectome surgery...
May 20, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28527653/ultrasound-biomicroscopy-measurement-of-schlemm-s-canal-in-pediatric-patients-with-and-without-glaucoma
#2
Anika Tandon, Caroline Watson, Ramesh Ayyala
PURPOSE: To compare the diameter of Schlemm's canal in children with and without congenital glaucoma as measured in vivo by means of ultrasound biomicroscopy. METHODS: In this prospective single-center study of pediatric subjects (<18 years of age) the diameter of Schlemm's canal in nonglaucomatous and glaucomatous eyes was compared. An 80 MHz iUltrasound probe (iScience Interventional Inc, Menlo Park, CA) placed near the limbus was used to identify and measure the canal's diameter with special attention to the anterior segment anatomy (especially in subjects with congenital glaucoma)...
May 17, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28526283/combination-of-anterior-segment-optical-coherence-tomography-modalities-to-improve-accuracy-of-rectus-muscle-insertion-location
#3
Michael J Venincasa, Carla J Osigian, Kara M Cavuoto, Julia D Rossetto, Hilda Capo
No abstract text is available yet for this article.
May 16, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28525962/association-of-lunate-morphology-with-carpal-instability-in-scapholunate-ligament-injury
#4
Eric Quan Pang, Nathan Douglass, Robin N Kamal
BACKGROUND: We examined the relationship between lunate morphology (type 1 without a medial facet; type II with a medial facet) and dorsal intercalated segmental instability (DISI) in patients with scapholunate ligament injuries. We tested the primary null hypothesis that there is no relationship between lunate morphology and development of DISI. Secondary analysis compared the agreement of classifying lunate morphology based on the presence of a medial lunate facet, capitate-to-triquetrum (CT) distance, and magnetic resonance imaging (MRI)...
May 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28525492/degenerative-cervical-disc-disease-long-term-changes-in-sagittal-alignment-and-their-clinical-implications-after-cervical-interbody-fusion-cage-subsidence-a-prospective-study-with-standalone-lordotic-tantalum-cages
#5
Félix Tomé-Bermejo, Julián A Morales-Valencia, Javier Moreno-Pérez, Juan Marfil-Pérez, Elena Díaz-Dominguez, Angel R Piñera, Luis Alvarez
STUDY DESIGN: A retrospective, observational study of prospectively collected outcomes. OBJECTIVE: To investigate the long-term clinical course of anterior cervical discectomy and fusion with interbody fusion cages (ACDF-IFC) with lordotic tantalum implants and to correlate the radiologic findings with the clinical outcomes, with special emphasis on the significance and the influence of implant subsidence. SUMMARY OF BACKGROUND DATA: Cage subsidence is the most frequently reported complication after ACDF-IFC...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525488/artificial-disk-replacement-combined-with-fusion-versus-2-level-fusion-in-cervical-2-level-disk-disease-with-a-5-year-follow-up
#6
Gyu Yeul Ji, Chang Hyun Oh, Dong Ah Shin, Yoon Ha, Seong Yi, Keung Nyun Kim, Hyun Cheol Shin, Do Heum Yoon
STUDY DESIGN: Prospective study. OBJECTIVE: The purpose of this study was to compare the long-term clinical and radiologic outcomes of hybrid surgery (HS) and 2-level anterior cervical discectomy and fusion (2-ACDF) in patients with 2-level cervical disk disease. SUMMARY OF BACKGROUND DATA: In a previous study with a 2-year follow-up, HS was shown to be superior to 2-ACDF, with a better Neck Disability Index (NDI) score, less postoperative neck pain, faster C2-C7 range of motion (ROM) recovery, and less adjacent ROM increase...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525482/artificial-cervical-disk-replacement-for-the-treatment-of-adjacent-segment-disease-after-anterior-cervical-decompression-and-fusion
#7
Sheng Bin, Huang Xiangwang, Xiao Sheng, Xiang Tiecheng, Liu Xiangyang, Zhang Yi, Liu Bin
STUDY DESIGN: Retrospective study. OBJECTIVE: To evaluate the outcome of artificial cervical disk replacement (ACDR) for the treatment of adjacent segment disease (ASD) after anterior cervical decompression and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF is the useful procedure for degenerative cervical diseases. However, studies have reported accelerated degeneration of functional spinal units adjacent to the fusion site after ACDF. MATERIALS AND METHODS: Between January 2004 and January 2011, 32 inpatients (18 male, 14 female; age, 38-61 y; mean, 48 y) underwent ACDR for the treatment of ASD after previous ACDF (single-level: n=12; 2-level: n=15; 3-level: n=5)...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525481/comparison-of-the-clinical-and-radiographic-results-between-cervical-artificial-disk-replacement-and-anterior-cervical-fusion-a-6-year-prospective-nonrandomized-comparative-study
#8
Wei Tian, Kai Yan, Xiao Han, Jie Yu, Peihao Jin, Xiaoguang Han
STUDY DESIGN: Prospective nonrandomized comparative study. OBJECTIVE: To compare the long-term clinical and radiographic results of cervical artificial disk replacement (CADR) and anterior cervical discectomy and fusion (ACDF), and to provide our evidence if CADR could reduce adjacent segment degeneration (ASD). SUMMARY OF BACKGROUND DATA: CADR is widely used in spine surgery today. Despite the short-term results of it having been ascertained, the long-term results are still under observation...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525475/a-comparison-of-multilevel-anterior-cervical-discectomy-and-corpectomy-in-patients-with-4-level-cervical-spondylotic-myelopathy-a-minimum-2-year-follow-up-study-multilevel-anterior-cervical-discectomy
#9
Zhonghai Li, Jiancheng Huang, Zhizhong Zhang, Fengning Li, Tiesheng Hou, Shuxun Hou
STUDY DESIGN: Retrospective clinical series. OBJECTIVES: To compare perioperative parameters, clinical outcomes, radiographic parameters, and complication rates of segmental anterior cervical corpectomy and fusion (sACCF) plus preservation of middle vertebrae with those of multilevel anterior cervical discectomy and fusion (mACDF) in 70 patients with 4-level cervical spondylotic myelopathy (CSM). METHODS: Between July 2006 and May 2011, 70 consecutive patients [49 males and 21 females; mean age 56...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525471/cervical-disk-replacement-with-discover-versus-fusion-in-a-single-level-cervical-disk-disease-a-prospective-single-center-randomized-trial-with-a-minimum-2-year-follow-up
#10
Marjan Rožanković, Sergej M Marasanov, Miroslav Vukić
STUDY DESIGN: Prospective randomized study. OBJECTIVE: To compare the clinical outcome after Discover arthroplasty versus anterior cervical discectomy and fusion (ACDF) in patients treated for symptomatic single-level cervical disk disease. SUMMARY OF BACKGROUND DATA: ACDF is still the gold standard for surgical treatment of cervical spine degenerative disk disease. However, results of many studies suggest that it may cause degenerative changes at levels immediately above and below the fusion, known as adjacent segment degenerative disease...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28524151/-etiopathogenesis-of-ocular-ischemic-syndrome
#11
D К Makhkamova
Ocular ischemic syndrome (OIS) is a collection of symptoms of carotid and ophthalmic artery disease of common genesis accompanied by ischemia of eyeball membranes. Specifically, the intraocular blood flow becomes impaired due to inflow reduction or arrest, while the venous outflow remains patent. Causes of OIS include arterial hypertension, atherosclerosis, diabetes, aortoarteritis and other vascular diseases. Clinical features depend on the extent, nature, and site of vascular involvement as well as the concurrent pathology...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28524144/-new-approaches-to-the-treatment-of-keratoconjunctivitis-sicca
#12
T N Safonova, O V Gladkova, I A Novikov, V I Boev, A A Fedorov
A new method has been developed for the treatment of severe forms of keratoconjunctivitis sicca (KCS) that involves the use of an original cyclosporine A (CyA) saturated soft contact lens (SCL) together with preservative-free artificial tears therapy. AIM: to evaluate the effectiveness of the newly developed treatment for KCS based on the use of medical SCL saturated with 0.05% CyA. MATERIAL AND METHODS: The patients (43 men, 60 eyes) with severe KCS were divided into 2 groups...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28523339/medial-meniscal-extrusion-a-validation-study-comparing-different-methods-of-assessment
#13
Luke D Jones, Stephen J Mellon, Neil Kruger, Andrew P Monk, Andrew J Price, David J Beard
PURPOSE: Longitudinal cohort studies of knee OA aetiology use MRI to assess meniscal extrusion within the same knee at sequential time points. A validated method of assessment is required to ensure that extrusion is measured at the same location within the knee at each time point. Absolute perpendicular extrusion from the tibial edge can be assessed using the reference standard of segmentation of the tibia and medial meniscus. This is labour intensive and unsuitable for large cohorts...
April 21, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28521845/hiv-infected-individuals-on-long-term-antiretroviral-therapy-are-at-higher-risk-for-ocular-disease
#14
E Schaftenaar, N S Khosa, G S Baarsma, C Meenken, J A McINTYRE, A D M E Osterhaus, G M G M Verjans, R P H Peters
Introduction of antiretroviral therapy (ART) has dramatically reduced the incidence of infectious ocular diseases in human immunodeficiency virus (HIV)-infected individuals. However, the effects of long-term ART and chronic HIV infection on the eye are ill-defined. This study determined the occurrence and severity of ocular diseases among 342 participants in a rural South African setting: HIV-naïve (n = 105), HIV-infected ART-naïve (n = 16), HIV-infected on ART for 36 months (long-term ART; n = 165). More HIV-infected participants presented with an external eye condition, in particular blepharitis, than HIV-naïve individuals (18% vs...
May 19, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28521823/t1rho-and-t2-relaxation-times-of-the-normal-adult-knee-meniscus-at-3t-analysis-of-zonal-differences
#15
Shoichiro Takao, Tan B Nguyen, Hon J Yu, Shigeo Hagiwara, Yasuhito Kaneko, Taiki Nozaki, Seiji Iwamoto, Maki Otomo, Ran Schwarzkopf, Hiroshi Yoshioka
BACKGROUND: Prior studies describe histological and immunohistochemical differences in collagen and proteoglycan content in different meniscal zones. The aim of this study is to evaluate horizontal and vertical zonal differentiation of T1rho and T2 relaxation times of the entire meniscus from volunteers without symptom and imaging abnormality. METHODS: Twenty volunteers age between 19 and 38 who have no knee-related clinical symptoms, and no history of prior knee surgeries were enrolled in this study...
May 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28520651/laparoscopic-management-of-hepatocellular-carcinoma-a-critical-reappraisal
#16
David Fuks, Luca Aldrighetti, Long R Jiao, Go Wakabayashi, Paolo Limongelli
Following the introduction of the first laparoscopic liver resection, after ∼25 years, a critical reappraisal seems to be warranted. Liver resection represents the first choice for curing early hepatocellular carcinoma (HCC) allowing a curative chance also in selected patients with intermediate stage tumors. The criteria for liver resectability by laparoscopy remains the same for open surgery, which is oncological criteria (absence of extrahepatic tumor location; completely resectable R0 resection), anatomic (resectability of involved segment with its own blood surely and biliary drainage; absence of vascular invasion of portal or hepatic veins) and technical (possibility to leave in place a residual volume ≥40%)...
May 17, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28520627/posterior-scleral-melanocytosis-a-novel-fundus-finding-masquerading-as-a-choroidal-nevus
#17
Rosa Dolz-Marco, Dov B Sebrow, K Bailey Freund
PURPOSE: To report a case of "posterior scleral melanocytosis," a pigmented lesion of the posterior sclera that clinically resembles a flat choroidal nevus. METHODS: Case report of a patient with posterior scleral melanocytosis. Multimodal imaging, including swept source optical coherence tomography, was used to demonstrate the scleral location of the pigmented lesion and to distinguish its features from a typical choroidal nevus present in the same eye. RESULTS: An 86-year-old woman was seen for regular follow-up for neovascular age-related macular degeneration in her right eye and 2 pigmented lesions in her left eye, both presumed to be choroidal nevi...
May 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28520595/decreased-visual-acuity-by-an-irregular-corneal-posterior-surface-after-repeat-descemet-stripping-automated-endothelial-keratoplasty
#18
Hiroyuki Yazu, Takefumi Yamaguchi, Murat Dogru, Yoshiyuki Satake, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To investigate the impact of higher-order aberrations (HOAs) on visual acuity after repeat Descemet stripping automated endothelial keratoplasty (DSAEK) in the same eyes. METHODS: This retrospective comparative case series includes 23 patients who underwent DSAEK twice in the same eyes (46 DSAEK in total). We evaluated the HOAs of the anterior and posterior corneal surfaces, and total cornea using the Fourier analysis data from anterior segment optical coherence tomography...
May 16, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28516453/dba-2j-mouse-model-for-experimental-glaucoma-pitfalls-and-problems
#19
Anita J Turner, Roshana Vander Wall, Vivek Gupta, Alex Klistorner, Stuart L Graham
PURPOSE: The DBA/2J mouse has been described as a model for congenital experimental glaucoma. It develops anterior segment anomalies with synechiae and pigment dispersion leading to raised intraocular pressure (IOP) and glaucomatous damage. However there are serious practical considerations when using this model in longitudinal studies. METHODS: We followed 118 mice from 12 - 48 weeks of age in a pharmaceutical trial. Here we report on the findings in control animals (n=37)...
May 18, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28514956/transcriptome-analysis-for-the-identification-of-cellular-markers-related-to-trabecular-meshwork-differentiation
#20
Padmapriya Sathiyanathan, Cheryl Y Tay, Lawrence W Stanton
BACKGROUND: Development of primary open-angle glaucoma (POAG) is associated with the malfunctioning trabecular meshwork (TM). Cell therapy offers great potential for the treatment of POAG, but requires the generation of functional TM cells in vitro to replace the lost/dysfunctional cells. TM differentiation in vitro from various stem cell types must be monitored by the expression of specific markers. However, no single definitive marker of the TM has been identified. RESULTS: To identify robust markers of TM differentiation, we performed global transcriptome profiling using high-density oligonucleotide microarray on ex vivo TM tissue and cultured TM progenitors...
May 17, 2017: BMC Genomics
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