TC thorax lung pulmonary

BACKGROUND: The aim of the study was the assessment of the clinical usefulness of scintigraphy with (99m)Tc-EDDA/HYNIC-TOC for purposes of a differential diagnosis of SPNs by means of a visual inspection and semi-quantitative assessment of uptake intensity of the radiopharmaceutical (RPh). MATERIAL AND METHODS: In 53 patients (32 males and 21 females at the ages between 38 and 78 years, mean value 57) with SPN on chest radiographs or CT scans, of diameters from 1 to 5...

This study was conducted to assess the feasibility of using Tc-99m labelled 2-methoxy isobutyl isonitrile (MIBI) scintigraphy, to evaluate benign and malignant intratoracic lesions and to assess the value in the differential diagnosis. The eligible population of the study included randomly selected 37 patients examined in Kocaeli University Pulmonary Clinic (19 men, 18 women) who had a abnormality in the PA chest X-ray and hadn't received any therapy. After intravenous injection of 15-25 mCi Tc-99m MIBI, early (10 minutes) and delayed (2...

STUDY OBJECTIVE: The validation of electrical impedance tomography (EIT) for measuring regional ventilation distribution by comparing it with single photon emission CT (SPECT) scanning. DESIGN: Randomized, prospective animal study. SETTINGS: Animal laboratories and nuclear medicine laboratories at a university hospital. PARTICIPANTS: Twelve anesthetized and mechanically ventilated pigs. INTERVENTIONS: Lung injury was induced by central venous injection of oleic acid...

PURPOSE: To investigate whether changes in diethylenetriamine pentaacetic acid (DTPA) aerosol clearance lung scans predict the development of radiation pneumonitis. METHODS AND MATERIALS: Thirty-three patients with advanced non-small-cell lung cancer were treated with palliative radiation therapy to thorax. All patients were subjected to pretreatment and post-treatment DTPA aerosol clearance lung scans. The clearance t1/2 values were compared using the paired t test...

Pulmonary involvement secondary to Waldenstrom's macroglobulinemia (WMG) is described in a 40-year-old male by incidental findings on a bone scan. He was examined for right leg pain, and bone scan revealed unexpected pulmonary uptake of Tc-99m MDP. CT scan of the thorax revealed pleural effusion and slightly disseminated micronoduler density increase in the right lung and parenchymal infiltration in the left lung. Transdermal lung biopsy demonstrated diffuse infiltration of lymphoplasmocytoids. Reporting the presence of pulmonary involvement is important because it may prevent morbidity from pulmonary dysfunction...

PURPOSE: To determine the biodistribution of Tc-99m labeled somatostatin receptor-binding peptide (Depreotide) on planar and SPECT studies of the thorax and upper abdomen in order to improve diagnostic accuracy. METHODS AND MATERIALS: Retrospectively 29 planar and SPECT studies from 28 patients (all males, average age of 65.79) were reviewed. All the patients had been referred for evaluation of solitary pulmonary nodules. Two to four hours after IV injection of 555- to 740-MBq (15-20 mCi) Tc-99m Depreotide, anterior and posterior total body images, and anterior, posterior, right lateral and left lateral planar images were obtained, and thoracic SPECT was acquired with a three-head gamma camera...

INTRODUCTION: Respiratory symptoms (stridor) in thyroid diseases are rather common, but often overlooked, especially in older people in whom they may be misinterpreted as asthma or chronic bronchitis. MATERIAL AND METHODS: To assess the value of lung function tests for differential diagnosis we used these tests in 33 patients with upper airway obstruction caused by an enlargement of the thyroid gland. The clinical examination consisted of an evaluation of the respiration, examination of the movement of the vocal chords, thyroid parameters, Tc scintigraphy, ultrasound examination, and X-ray examination of the thorax and trachea up to the level of the glottis, supplemented by a CT scan if needed...

PURPOSE: The lower thorax and upper abdomen are visualized during cardiac acquisition of rest Tl-201 and stress Tc-99m tetrofosmin gated SPECT. Thus, abnormal Tl-201 localization in these areas and in organs such as parts of the lungs, liver, spleen, and kidneys can be observed, including rotating raw cine data. MATERIALS AND METHODS: Other than cardiac images, the authors retrospectively reviewed Tl-201 rotating (raw data) images of 235 patients. Abnormal findings in the lungs, liver, spleen, and kidneys were identified that correlated with the patients' clinical information; radiographic findings, including computed tomography and ultrasonography of the abdomen; other scintigraphic studies; and laboratory findings...

UNLABELLED: Lung scintigraphy is the primary tool for diagnostics of pulmonary embolism. A perfusion study is often complemented by a ventilation study. Intermediate probability scans are frequent. Our goal was to develop a fast method for tomographic ventilation and perfusion scintigraphy to improve the diagnostic value of lung scintigraphy. METHODS: SPECT was performed with a dual-head gamma camera. Acquisition parameters were determined using a thorax phantom...

The purpose of this study was to determine the frequency of hypoxemia and pulmonary mineralization using 99mTc-methylene diphosphonate (99mTc-MDP) in dogs with pituitary-dependent hyperadrenocorticism (PDH). Twenty-one dogs with PDH were prospectively evaluated using thoracic radiography, arterial blood gas analysis, and bone phase and pulmonary perfusion scintigraphy (using 99mTc-macro-aggregated albumin [99mTc-MAA]). The radiographs and bone and perfusion studies were evaluated subjectively. An averaged quantitative count density ratio was calculated between the thorax and cranial thoraco-lumbar vertebrae from lateral thoracic 99mTc-MDP images...

A 28-year-old woman with a deformed thorax and kyphoscoliosis associated with Klippel-Feil syndrome developed respiratory failure with pulmonary hypertension. Pulmonary 133Xe ventilation and 99mTc-MAA perfusion scintigraphies showed maldistributions of lung ventilation and perfusion, and noticeably delayed 133Xe washout from the lungs. Dynamic breathing MR imaging showed poor and/or asynchronous respiratory movements of the chest wall and diaphragm. These findings indicate that the perfusion-ventilation imbalance, the decreased ventilatory turnover, and expiratory flow from the alveolar space partly derived from the impaired respiratory mechanics may be responsible for the respiratory complications in this patient...

The phenomenon of reverse mismatched ventilation-perfusion on pulmonary scintigraphy is a fairly common occurrence. We present a patient who was experiencing decreasing oxygen saturation and had a reverse mismatched ventilation-perfusion imaging pattern associated with radiotracer retention in a main bronchus. Technetium-99m-DTPA aerosol lung imaging showed tracer retention in the trachea and right main bronchus, absent ventilation in the right lung, and normal ventilation in the left lung. Technetium-99m-MAA perfusion lung images showed normal perfusion of the left lung and some perfusion in the right lung...

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UNLABELLED: Pulmonary hypoplasia was diagnosed sonographically in 32 fetuses from 20 to 33 weeks of gestation. In addition to standard biometry, transverse thoracic diameter (TTD), sagittal thoracic diameter (TSD), thoracic circumference (TC) and lung diameter (LD) were measured in all cases and compared with known nomograms. The fetuses were divided into five groups according to the main sonographic findings: group 1-skeletal dysplasia; group 2-renal agenesis; group 3-diaphragmatic hernia; group 4-hydrothorax; and group 5-others...

The case of a 14-year-old girl with Behcet syndrome is described. Besides painful and recurrent oral ulcerations, the patient had a cough and intermittent hemoptysis. The initial chest roentgenogram revealed bilateral parahilar opacities. CT and MRI scans of the thorax showed bilateral thrombosing aneurysms of the pulmonary arteries. Pulmonary blood flow imaging was performed after technegas ventilation lung scanning and Tc-99m MAA injection using a first-pass radionuclide angiography procedure. Altered blood flow in the left pulmonary artery was shown...

PURPOSE: Continuous lateral rotational therapy (CLRT) <40 degrees is a method of altering the position of the ventilated patient to help clear secretions from the lung. CLRT has not been shown to reduce the incidence of atelectasis or pneumonia but potentially offers a way to maximize positional drainage in these patients without producing adverse effects. Treatment intervention, bracketed by two (nonrotational) control periods. The purpose of this study was to determine if CLRT alters mucus transport in critically ill, intubated patients in the intensive care unit of a teaching hospital...

Measurement of the clearance rate of inhaled aerosols of 99mTc-diethylenetriamine pentaacetic acid (DTPA) from distal airway to pulmonary capillary is a sensitive technique for the detection of lung injury. As the solute diffuses across the blood-gas barrier, the concentration in circulating blood increases, giving rise to a background signal superimposed on the signal from residual DTPA in the airway. Background subtraction is conventionally based on the thigh, but this tissue has the disadvantage in that its composition, in terms of the relative volumes of its extracellular extravascular and intravascular compartments (a ratio of approximately 4:1), is quite different from that of the lung (<1:6)...

A 67-yr-old woman with a history of myocardial infarct was admitted to emergency for marked dyspnea, nonproductive cough, nausea and fever. The thorax X-ray revealed a bilateral alveolar and interstitial infiltration pattern with basal accentuation. The cardiac examinations were normal. Technegas ventilation and Tc-99m-macroaggregated albumin (MAA) perfusion scans were performed to rule out pulmonary embolism. Bilateral multiple ventilation defects with normal perfusion was observed. The patient had been taking nitrofurantoin for four days for a bladder infection...

Tc-99m MIBI is taken up avidly by viable tumor tissue and does not accumulate in the necrotic carcinoma. We present a patient who underwent Tc-99m MIBI and Tc-99m HMDP thoracic SPECTs: a large area of increased MIBI uptake with central photopenia (ring appearance) in the right upper lung localizes bone imaging agent and does not localize multiple areas of intense uptake in the metastatic hilar mediastinum lymph nodes. Rapid growth of tumor cells in the lung leading to central necrosis/ischemia accounts for bone imaging agent localization in the tumor, as well as the ring-appearance of lung mass on Tc-99m MIBI imaging...

The current prospective, longitudinal study was designed to define the confidence limits and characteristics of growth for fetal cardiac, thoracic, and pulmonary dimensions from 20 to 40 weeks' gestation. We tested the hypotheses that (1) CC/TC, (2) CC/AC, (3) TC/HC, and (4) TC/AC ratios remain constant throughout this period of gestation. The four-chamber view of the fetal heart in diastole, in the absence of fetal breathing, was used as a standard reference for sonographic measurement of cardiac, thoracic, and left and right pulmonary dimensions in a longitudinal study of 45 uncomplicated pregnancies...