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https://www.readbyqxmd.com/read/27717861/epidemiological-characteristics-practice-of-ventilation-and-clinical-outcome-in-patients-at-risk-of-acute-respiratory-distress-syndrome-in-intensive-care-units-from-16-countries-provent-an-international-multicentre-prospective-study
#1
Ary Serpa Neto, Carmen S V Barbas, Fabienne D Simonis, Antonio Artigas-Raventós, Jaume Canet, Rogier M Determann, James Anstey, Goran Hedenstierna, Sabrine N T Hemmes, Greet Hermans, Michael Hiesmayr, Markus W Hollmann, Samir Jaber, Ignacio Martin-Loeches, Gary H Mills, Rupert M Pearse, Christian Putensen, Werner Schmid, Paolo Severgnini, Roger Smith, Tanja A Treschan, Edda M Tschernko, Marcos F V Melo, Hermann Wrigge, Marcelo Gama de Abreu, Paolo Pelosi, Marcus J Schultz
BACKGROUND: Scant information exists about the epidemiological characteristics and outcome of patients in the intensive care unit (ICU) at risk of acute respiratory distress syndrome (ARDS) and how ventilation is managed in these individuals. We aimed to establish the epidemiological characteristics of patients at risk of ARDS, describe ventilation management in this population, and assess outcomes compared with people at no risk of ARDS. METHODS: PRoVENT (PRactice of VENTilation in critically ill patients without ARDS at onset of ventilation) is an international, multicentre, prospective study undertaken at 119 ICUs in 16 countries worldwide...
October 4, 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27686460/esicm-lives-2016-part-two-milan-italy-1-5-october-2016
#2
S Sivakumar, F S Taccone, K A Desai, C Lazaridis, M Skarzynski, M Sekhon, W Henderson, D Griesdale, L Chapple, A Deane, L Williams, R Strickland, K Lange, D Heyland, M Chapman, M J Rowland, P Garry, J Westbrook, R Corkill, C A Antoniades, K T Pattinson, G Fatania, A J Strong, R B Myers, C Lazaridis, C M Jermaine, C S Robertson, C G Rusin, J Hofmeijer, L Sondag, M C Tjepkema-Cloostermans, A Beishuizen, F H Bosch, M J A M van Putten, L Carteron, C Patet, D Solari, M Oddo, M A Ali, C Dias, R Almeida, A Vaz-Ferreira, J Silva, E Monteiro, A Cerejo, A P Rocha, A A Elsayed, A M Abougabal, B N Beshey, K M Alzahaby, S Pozzebon, A Blandino Ortiz, S Cristallini, O Lheureux, A Brasseur, J L Vincent, J Creteur, F S Taccone, M Hravnak, K Yousef, Y Chang, E Crago, R M Friedlander, S A Abdelmonem, S A Tahon, T A Helmy, H S Meligy, F Puig, I Dunn-Siegrist, J Pugin, S Gupta, D Govil, S Srinivasan, S J Patel, J K N, A Gupta, D S Tomar, M Shafi, R Harne, D P Arora, N Talwar, S Mazumdar, E E Papakrivou, D Makris, E Manoulakas, B Tsolaki, B Karadodas, E Zakynthinos, I Palacios Garcia, A Diaz Martin, V Sanchez Encinares, M Pachón Ibañez, J Garnacho Montero, G Labrador, T Cebrero Cangueiro, V Poulose, J Koh, J W Kam, H Yeter, A Kara, O Aktepe, A Topeli, I Tsolakoglou, G Intas, P Stergiannis, A A Kolaros, E Chalari, E Athanasiadou, A Martika, G Fildisis, V Faivre, C Mengelle, B Favier, D Payen, A Poppe, M S Winkler, E Mudersbach, J Schreiber, M L Wruck, E Schwedhelm, S Kluge, C Zöllner, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, A García-de la Torre, M V de la Torre-Prados, T Tsvetanova-Spasova, P Nuevo-Ortega, C Rueda-Molina, A Fernández-Porcel, E Camara-Sola, L Salido-Díaz, A García-Alcántara, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, D E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, B Suberviola, J Riera, L Rellan, M Sanchez, J C Robles, E Lopez, R Vicente, E Miñambres, M 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Sakamoto, S Inoue, K C Yamada, H Koami, T Miike, F Nagashima, T Iwamura, A Boscolo, V Lucchetta, E Piasentini, D Bertini, L Manesso, L Spiezia, P Simioni, C Ori, R B Souza, A M Martins, A M A Liberatore, Y R Kang, M N Nakamae, J C F Vieira, I H J Koh, K Hanslin, F Wilske, P Skorup, J Sjölin, M Lipcsey, W Jin Long, C Er Zhen, A Vakalos, V Avramidis, S H Wu, L J Shyu, C H Li, C H Yu, H C Chen, C H Wang, K H Lin, Z E Aray, C F Gómez, A P Tejero, D D Monge, V M Losada, C M Tarancón, S D Cortés, A M Gutiérrez, T P Álvarez, A Rouze, K Jaffal, S Six, K Stolz, V Cattoen, S Nseir, J M Arnal, M Saoli, D Novotni, A Garnero, T Becher, V Buchholz, D Schädler, I Frerichs, N Weiler, N Eronia, T Mauri, S Gatti, E Maffezzini, A Bronco, L Alban, T Sasso, C Marenghi, G Grasselli, A Pesenti, G Bellani, A Al-Fares, L Del Sorbo, S Anwar, F Facchin, S Azad, R Zamel, N Ferguson, M Cypel, S Keshavjee, E Fan, E Durlinger, A Spoelstra-de Man, B Smit, H J de Grooth, A Girbes, H Oudemans-van Straaten, Y Smulders, M A Alfaro, F Parrilla, A Meli, M Pellegrini, N Rodriguez, J M Goyeneche, I Morán, H Aguirre, J Mancebo, S J H Heines, U Strauch, D C J J Bergmans, P Blankman, A Shono, D Hasan, D Gommers, W Y Chung, K S Lee, Y J Jung, J H Park, S S Sheen, K J Park, R Worral, S Denham, P Isherwood, S E Rees, S Larraza, N Dey, S Spadaro, J B Brohus, R W Winding, C A Volta, D S Karbing, F Ampatzidou, A Vlachou, G Kehagioglou, T Karaiskos, A Madesis, C Mauromanolis, N Michail, G Drossos, N Saraj, S Rijkenberg, H M Feijen, H Endeman, A A J Donnelly, E Morgan, H Garrard, H Buckley, L Russell, N Haase, A Perner, C Goh, K Mouyis, C L N Woodward, J Halliday, G B Encina, J Ros, L Lagunes, J Tabernero, F Bosch, J Rello, D García Huertas, F Manzano, E Morente-Constantin, B Rivera-Ginés, M Colmenero-Ruiz, A Naharro Abellán, L Pérez Pérez, A Pérez Lucendo, P Matía Almudévar, J Palamidessi Domínguez, P Rodríguez Villamizar, J García Sanz, I Fernandez Simon, B Lobo Valbuena, S Alcantara Carmona, M Pais, S Ramalingam, C Díaz, L Fox, M Santafe, P Barba, M García, S Leal, M Pérez, M L Pérez Pérez, A Naharro Abellán, A Pérez Lucendo, P Matia Almudevar, J Palamidessi Domínguez, P Rodríguez Villamizar, J Veganzones, I Fernandez Simón, B Lobo Valbuena, N Martínez, S Alcántara Carmona, I Moors, D Mokart, F Pène, J Lambert, A Kouatchet, J Mayaux, F Vincent, M Nyunga, F Bruneel, L Laisne, A Rabbat, C Lebert, P Perez, M Chaize, A Renault, A P Meert, R Hamidfar, M Jourdain, M Darmon, B Schlemmer, S Chevret, V Lemiale, E Azoulay, D Benoit, D Martins-Branco, M Sousa, S Marum, M J Bouw, G Galstyan, P Makarova, E Parovichnikova, L Kuzmina, V Troitskaya, N Drize, E Gemdzhian, V Savchenko, H C Chao, E Kılıc, B Demiriz, M L Uygur, M Sürücü, K Cınar, A E Yıldırım, K Kiss, B Köves, V Csernus, Z Molnár, A Ntantana, D Matamis, S Savvidou, M Giannakou, M Gouva, G Nakos, V Koulouras, S Gaffney, E Black, R Docking, C Judge, T Drew, H Misran, R Munshi, L McGovern, M Coyle, L Dunne, E Deasy, P Lavin, A Fahy, D M Darcy, M Donnelly, N H Ismail, T Hall, K Wykes, J Jack, W C Ngu, P Morgan, J Ruiz-Ramos, P Ramirez, M Gordon, E Villarreal, J Frasquet, J L Poveda-Andrés, A Castellanos, C E Ijssennagger, S Ten Hoorn, A van Wijk, J M van den Broek, P R Tuinman, A M Elmenshawy, B D Hammond, G Gibbon, T Belcham, K Burton, L U Taniguchi, F J S Ramos, A K Momma, A P R Martins-Filho, J J Bartocci, M F D Lopes, M H Sad, C M Rodrigues, E M C Pires, J M Vieira, M A Leite, L D Murbach, E F Osaku, J Barreto, S T Duarte, S Taba, D Miglioranza, D P Gund, C F Lordani, C R L M Costa, S M Ogasawara, A C Jorge, P A D Duarte, S Spadaro, M Capuzzo, F Dalla Corte, S Terranova, G Scaramuzzo, A Fogagnolo, S Bertacchini, A Bellonzi, R Ragazzi, C A Volta, C Cruz, A Nunes, F Seabra Pereira, I Aragão, A F Cardoso, C Santos, M J Malheiro, H Castro, T Cardoso, J Paratz, J Kenardy, T Comans, F Coyer, P Thomas, R Boots, N Pereira, A Vilas-Boas, E Gomes, C Dias, J Torres, D Carvalho, E Molinos, C Vales, R Araújo, C Cruz, A Nunes, F Seabra Pereira, A F Cardoso, C Santos, M J Malheiro, H Castro, T Cardoso, L Karnatovskaia, K Philbrick, G Ognjen, M Clark, R Molina Montero, J Luján Varas, L Alcázar Sánchez-Elvira, C Pintado Delgado, P Villa Díaz, B Llorente Ruiz, A Pardo Guerrero, J A Cambronero Galache, R Jiménez, S Rebollo, O Alejandro, A Fernández, S Moreno, L Herrera, A Ojados, M Galindo, J Murcia, M Contreras, S Sánchez-Argente, Y Bonilla, M D Rodríguez, J M Allegue, Ö Cakin, H Parlak, H Kirca, F Mutlu, B Aydınlı, M Cengiz, A Ramazanoglu, E-J Jung, S-Y Oh, H Lee, N M Filgueiras Filho, E F Ricaldi, S S Gomes, B B Ramos, C V De Lucia, C S Ballalai, J C A Oliveira, G P Araponga, L N Veiga, C S Silva, M E Garrido, J Cebrián Domenech, A Pinos Montalvo, T Ciges Chornet, P Concha Martinez, M Piñol Ribas, R Gimeno Costa, A Castellanos Ortega, C Forbes, H Prescott, A Lal, F A Khan, E G Dela Pena, J S Dizon, P P P Perez, C M J Wong, M Muñoz Garach, O Moreno Romero, R Ramirez Puerta, F Acosta Diaz, A M Perez Bailon, A Carranza Pinel, L Peñas Maldonado, M S Kalaiselvan, R L Siva Kumar, M K Renuka, A S Arun Kumar, S De Rosa, F Ferrari, S Carboni Checcacci, A Rigobello, M Joannidis, F Politi, A Pellizzari, R Bonato, A Fernandez-Carmona, I Macias-Guarasa, R Gutierrez-Rodriguez, P Martinez-Lopez, M A Diaz-Castellanos, A Fernandez-Carmona, M Arias-Diaz, E Aguilar-Alonso, I Macias-Guarasa, P Martinez-Lopez, M A Diaz-Castellanos, R N Nikandish, V Artemenko, A Budnyuk, G Li Bassi, T Senussi, F Idone, E Aguilera Xiol, C Travierso, C Chiurazzi, A Motos, R Amaro, Y Hua, L Fernández-Barat, O T Ranzani, Q Bobi, M Rigol, A Torres, A Youn, J Gyung Hwang, M Muñoz Garach, O Moreno Romero, M E Yuste Ossorio, F Acosta Diaz, A M Perez Bailon, A Carranza Pinel, L Peñas Maldonado, C Teixeira, H Figueira, R Oliveira, A Mota, I Aragão, O Kamp, O Cruciger, M Aach, C Kaczmarek, C Waydhas, T A Schildhauer, U Hamsen, M Camprubí-Rimblas, L Chimenti, R Guillamat-Prats, T Lebouvier, J Bringué, J Tijero, M N Gómez, L Blanch, A Artigas, G Tagliabue, M Ji, J V Suneby Jagers, P A Easton, R B Souza, A M A Liberatore, A M C R P F Martins, J C F Vieira, Y R Kang, M N Nakamae, I H J Koh, J Y Hong, M H Shin, M S Park, A Pomprapa, P A Pickerodt, M B T Hofferberth, M Russ, W Braun, M Walter, R Francis, B Lachmann, S Leonhardt, I H J Koh, R B Souza, A M C R P F Martins, J C F Vieira, A M A Liberatore, A Landaverde-López, N A Canedo-Castillo, A Esquivel-Chávez, P C Arvizu-Tachiquín, L A Sánchez-Hurtado, J A Baltazar-Torres, V Cardoso, A Krystopchuk, S Castro, L Melão, S Firmino, A Marreiros, C Granja, S Almaziad, A Kubbara, W Barnett, R Nakity, W Alamoudi, R Altook, T Tarazi, M Fida, F Safi, R Assaly, A Santini, M Milesi, T Maraffi, P Pugni, D T Andreis, M Cavenago, L Gattinoni, A Protti, G Perchiazzi, J B Borges, S Bayat, L Porra, L Broche, M Pellegrini, G Scaramuzzo, G Hedenstierna, A Larsson, M Pellegrini, G Hedenstierna, A Roneus, M Segelsjö, M C Vestito, A Larsson, G Perchiazzi, E Gremo, A Nyberg, M Castegren, A Pikwer, T Yoshida, D Engelberts, G Otulakowski, B Katira, M Post, N D Ferguson, L Brochard, M B P Amato, B P Kavanagh, N Koch, W Huber, J Hoellthaler, S Mair, V Phillip, R M Schmid, A Beitz, V Baladrón, F J Redondo Calvo, D Padilla, P Villarejo, R Villazala, A S Yuste, N Bejarano, R J Steenstra, H Banierink, J Hof, I C van der Horst, M W Nijsten, M Hoekstra, K Roedl, F Sterz, T Horvatits, K Horvatits, A Drolz, H Herkner, V Fuhrmann, M Kott, K Zitta, B Brandt, C Schildhauer, G Elke, L Hummitzsch, I Frerichs, N Weiler, M Albrecht, L Rey González, D Cabestrero Alonso, A Blandino Ortiz, R de Pablo Sánchez, J Higuera Lucas, K Roedl, F Sterz, A Drolz, K Horvatits, T Horvatits, H Herkner, V Fuhrmann, T Horvatits, A Drolz, K Roedl, K Rutter, A Ferlitsch, G Fauler, M Trauner, V Fuhrmann, T Horvatits, S Pischke, L Fischer, F Thaiss, M Koch, K Bangert, V Fuhrmann, S Kluge, A W Lohse, B Nashan, M Sterneck, S Faenza, A Siniscalchi, E Pierucci, E Mancini, D Ricci, C Gemelli, A Cuoghi, S Magnani, M Atti, F Sotos, J Cánovas, A López, A Burruezo, D Torres, M E Herrera-Gutierrez, J Barrueco-Francioni, D Arias-Verdú, R Lozano-Saez, G Quesada-Garcia, G Seller-Pérez, A Figueiredo, Y Anzola, R Pereira, L Bento, D Arias-Verdú, M Lai, M Deiana, J Barrueco-Francioni, M E Herrera-Gutierrez, G Seller-Perez, K Vardas, S Ilia, A Sertedaki, E Charmadari, C A Stratakis, E Briassouli, D Goukos, K Psarra, E Botoula, S Tsagarakis, E Mageira, C Routsi, S Nanas, G Briassoulis, A Boscolo, D Bertini, E Campello, V Lucchetta, E Piasentini, C M Radu, L Manesso, P Simioni, C Ori, H Su, Y M Lam, K Willis, V Pullar, R P Hubner, J L Tsang, L García de Guadiana-Romualdo, S Rebollo-Acebes, P Esteban-Torrella, R Jiménez-Sánchez, E Jiménez-Santos, A Ortín-Freire, A Hernando-Holgado, M D Albaladejo-Otón, L Coelho, L Rabello, J Salluh, I Martin-Loeches, A Rodriguez, S Nseir, P Póvoa, E Varis, V Pettilä, M Poukkanen, S Jacob, S Karlsson, A Perner, J Takala, E Wilkman, O H M Lundberg, L Bergenzaun, J Rydén, M Rosenqvist, O Melander, M S Chew, E Rodriguez-Ruiz, R Hernández Vaquero, A Lopez Lago, J L Garcia Allut, A Estany Gestal, M A Garcia Gonzalez, Y Kishihara, H Yasuda, S Rebollo, L García de Guadiana-Romualdo, R Jimenez, P Esteban Torrella, A Fernandez, S Sanchez, A Ortin, G Li Bassi, R Guillamat Prats, A Artigas, E Aguilera, D Marti, O T Ranzani, M Rigol, L Fernandez, M Ferrer, I Martin-Loeches, A Torres, V S Lanziotti, P Póvoa, L Pulcheri, M O Ribeiro, A P Barbosa, J R Lapa E Silva, M Soares, J I F Salluh, I Palacios Garcia, A Diaz Martin, M Gil Marqués, A Puppo Moreno, A Gutierrez Pizarraya, J Pachón Diaz, M Pachón Ibañez, Y Smani, M Mc Connell, L A Zhang, R S Parker, I Banerjee, G Clermont, E Norberg, J Oras, A Cuisinier, C Maufrais, J F Payen, S Nottin, G Walther, P Bouzat, S Arib, F Bilotta, R Badenes, F Rubulotta, S Mirek, I A Crippa, B Monfort, E Stazi, A Lozano Roig, J Creteur, F S Taccone, S Magnoni, M Marando, S Pifferi, V Conte, F Ortolano, M Carbonara, G Bertani, E Scola, M Cadioli, F Triulzi, A Colombo, N Stocchetti, H B Rotzel, A Serrano Lázaro, D Aguillón Prada, M Rodriguez Guimillo, C Sanchís Piqueras, J Romero Guia, M García Simon, A Mesejo Arizmendi, A Carratalá, S El Maraghi, A Yehia, M Bakry, A Shoman, F N Backes, M M Bianchin, S R R Vieira, A de Souza, A N Backes, C Klein, M S Kalaiselvan, M K Renuka, A S Arunkumar, A Lozano, O Lheureux, R Badenes, J L Vincent, J Creteur, F S Taccone, C Gallaher, S Cattlin, S Gordon, J Picard, V Fontana, O Bond, L Nobile, J L Vincent, J Creteur, F S Taccone, S Mrozek, L Delamarre, F Capilla, T Al-Saati, O Fourcade, T Geeraerts, A M Dominguez-Berrot, M Gonzalez-Vaquero, M E Vallejo-Pascual, D Gupta, B D Ivory, M Chopra, J McCarthy, C L Felderhof, C MacNeil, F Rubulotta, P Waldauf, M Maggiorini, F Duska, R R L Fumis, J M Vieira Junior, G Amarante, A Skorko, S Sanders, J Aron, R J Kroll, C Redfearn, P Krishnan, J E Khalil, F Kovari, N Kongpolprom, V Gulia, E Lourenço, L Melão, C Duro, G Baptista, A Alves, B Arminda, M Rodrigues, A Marreiros, C Granja, J Hayward, F Baldwin, R Gray, P A Katinakis, M Stijf, M Ten Kleij, M Jansen-Frederiks, R Broek, M de Bruijne, P E Spronk, K Sinha, M Luney, K Palmer, L Keating, M Abu-Habsa, R Bahl, N Baskaralingam, A Ahmad, L Kanapeckaite, P Bhatti, S Glace, S Jeyabraba, H F Lewis, A Kostopoulos, M Raja, A West, A Ely, L M Turkoglu, P Zolfaghari, J P Baptista, M P Marques, P Martins, J Pimentel, D Gupta, Y C Su, S Villacres, M E Stone, A Parsikia, S Medar, K P O'Dea, J Porter, N Tirlapur, J M Jonathan, S Singh, M Takata, M Abu-Habsa, A Ahmad, E McWhirter, R Lyon, M L Hariz, E Azmi, J Alkhan, S Honeybul, V Movsisyan, S Petrikov, Z Marutyan, I Aliev, A Evdokimov, E Antonucci, T Merz, C Hartmann, P Pelosi, E Calzia, P Radermacher, B Nußbaum, C Hartmann, M Huber-Lang, M Gröger, P Radermacher, B Nußbaum, B Nußbaum, E Antonucci, E Calzia, P Pelosi, P Radermacher, C Hartmann, E Svoren-Jabalera, E E Davenport, P Humburg, J Knight, C J Hinds, I J Jun, W J Kim, E H Lee, G Besch, A Perrotti, M Puyraveau, L Carteron, M Baltres, E Samain, S Chocron, S Pili-Floury, E P Plata-Menchaca, J Sabater-Riera, M Estruch, E Boza, F Sbraga, J Toscana-Fernández, E Bruguera-Pellicer, J Ordoñez-Llanos, X L Pérez-Fernández, P Cavaleiro, A Tralhão, M Arrigo, J-P Lopes, M Lebrun, B Cholley, J L PerezVela, H MarinMateos, J J Jimenez Rivera, M A Alcala Llorente, B Gonzalez De Marcos, F J Gonzalez Fernandez, C Garcia Laborda, D Fernandez Zamora, J C Lopez Delgado, C Imperiali, D Berbel-Franco, M Dastis, G Moreno-Gonzalez, J Perez-Sanchez, I Romera-Peregrina, R Abellan-Lencina, A Martinez-Pascual, V Fuentes-Mila, M Gonzalez-Romero, J Górka, K Górka, T Iwaniec, M Frołow, K Polok, J Fronczek, M Kózka, J Musiał, W Szczeklik, A González Pérez, P Florez Ordoñez, A Giribet, M A Alonso Cuervo, R Alonso Cuervo, M A Rodriguez Esteban, L Iglesias Fraile, C Ponte Mittelbrum, G Muñiz Albaiceta, F Ampatzidou, M Sileli, G Kehagioglou, A Madesis, T Karaiskos, C Moursia, H Maleoglou, K Leleki, G Drossos, Z Uz, Y Ince, R Papatella, E Bulent, P Guerci, C Ince, B De Mol, V Vicka, D Gineityte, D Ringaitiene, I Norkiene, J Sipylaite, C Möller, C Fleischmann, D O Thomas-Rueddel, V Vlasakov, B Rochwerg, P Theurer, L Gattinoni, K Reinhart, C S Hartog, A González Pérez, J Zanabili Al Sibai, P Martinez Camblor, P Alvarez Fernandez, J M García Gala, J Silba Guisasola, G Muñiz Albaiceta, T Tamura, T Yatabe, I Miyajima, K Yamashita, M Yokoyama, F Ampatzidou, G Kehagioglou, E Dalampini, M Nastou, A Baddour, A Ignatiadis, T Asteri, G Drossos, K E Hathorn, S W Purtle, C M Horkan, F K Gibbons, K B Christopher, M V Viana, T A Tonietto, L A Gross, V L Costa, A L J Tavares, B O Lisboa, R B Moraes, S R Vieira, L V Viana, M J Azevedo, G D Ceniccola, R S F Pequeno, T P Holanda, V S Mendonça, W M C Araújo, L S F Carvalho, E Segaran, L Vickers, K Brinchmann, I Wignall, F Rubulotta, I De Brito-Ashurst, R Del Olmo, M J Esteban, C Vaquerizo, R Carreño, V Gálvez, G Kaminsky, B Nieto, M Fuentes, M A De la Torre, E Torres, A Alonso, C Velayos, T Saldaña, A Escribá, J Grip, R Kölegård, P Sundblad, O Rooyackers, Ben Naser, F Jaziri, A Ben Jazia, M Barghouth, O Hentati, W Skouri, M El Euch, M Mahfoudhi, S Turki, K Ben Abdelghni, Ben Abdallah, B N M Maha, J Cánovas, F Sotos, A López, M Lorente, A Burruezo, D Torres, K Polok, A Włudarczyk, J Górka, A Hałek, J Musiał, W Szczeklik, A Ben Jazia, F Jaziri, M Bargouth, M Bennasr, S Turki, K Ben Abdelghani, T Ben Abdallah, H J de Grooth, I L Geenen, J J Parienti, H M Oudemans-van Straaten, H P Shum, H S King, K C Chan, W W Yan, J Gonzalez Londoño, C Lorencio Cardenas, M Morales Pedrosa, C Murcia Gubianas, C Fuster Bertolin, N Vila Batllori, J M Sirvent, K Wykes, J Jack, P Morgan, A Mukhopadhyay, H Y Chan, Y Kowitlawakul, D Remani, C S F Leong, C J Henry, Z A Puthucheary, N Mendsaikhan, T Begzjav, G Lundeg, M Dünser, E D Valenzuela Espinoza, S P Welsh, M F Motta, E Guerra, M C L Zerpa, F Zechner, M Furche, F Berdaguer, P N Rubatto Birri, A Risso-Vazquez, A Dubin, F D Masevicius, D Greaney, A Magee, G Fitzpatrick, R G Lugo-Cob, L A Sánchez-Hurtado, P C Arvizu-Tachiquín, B C Tejeda-Huezo, A A Cano-Oviedo, J A Baltazar-Torres, M S Aydogan, T Togal, A Taha, H Z Chai, C Kam, S S Yang Razali, V Sivasamy, L Y Kuan, V Poulose, M A Lopez Morales, S Castro, T Pires, L Melão, A Krystopchuk, I Pereira, C Granja, L U Taniguchi, E M C Pires, J M Vieira, L C P Azevedo
No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27410465/near-infrared-emitting-bodipy-trisdota-111-in-as-a-monomolecular-multifunctional-imaging-probe-from-synthesis-to-in-vivo-investigations
#3
Nicolas Maindron, Martin Ipuy, Claire Bernhard, Damien Lhenry, Mathieu Moreau, Sabin Carme, Alexandra Oudot, Bertrand Collin, Jean-Marc Vrigneaud, Peggy Provent, François Brunotte, Franck Denat, Christine Goze
A new generation of monomolecular imaging probes (MOMIP) based on a distyryl-BODIPY (BODIPY=boron-dipyrromethene) coupled with three DOTA macrocycles has been prepared (DOTA=1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid). The MOMIP presents good fluorescence properties and is very stable in serum. The bimodal probe was conjugated to trastuzumab, and an optical in vivo study showed high accumulation of the imaging agent at the tumor site. (111) In radiometallation of the bioconjugate was performed in high radiochemical yield, highlighting the potential of this new BODIPY-chelators derivative as a bimodal imaging probe...
August 26, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/26994779/clinical-application-of-the-provent-score-in-korean-patients-requiring-prolonged-mechanical-ventilation-a-10-year-experience-in-a-university-affiliated-tertiary-hospital
#4
Jeong Ha Mok, Yang Hee Kim, Eun Suk Jeong, Jung Seop Eom, Mi Hyun Kim, Ki Uk Kim, Min Ki Lee, Kwangha Lee
PURPOSE: We evaluated the clinical usefulness of a prognostic scoring system ("the ProVent score") in Korean patients requiring prolonged mechanical ventilation. MATERIAL AND METHODS: We retrospectively analyzed the data of 184 patients in a medical intensive care unit of a tertiary care hospital between January 2004 and December 2013. RESULTS: The patients' median age was 65 years, and 66.8% were male. One-year mortality was 67.4%. On day 21 of mechanical ventilation, the ProVent score was 0 in 13 patients (7...
June 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/26798519/nasal-expiratory-positive-airway-pressure-devices-provent-for-osa-a-systematic-review-and-meta-analysis
#5
REVIEW
Muhammad Riaz, Victor Certal, Gaurav Nigam, Jose Abdullatif, Soroush Zaghi, Clete A Kushida, Macario Camacho
Objective. To quantify the effectiveness of nasal expiratory positive airway pressure (nasal EPAP) devices or Provent as treatment for obstructive sleep apnea (OSA). Methods. PubMed and six other databases were searched through November 15, 2015, without language limitations. Results. Eighteen studies (920 patients) were included. Pre- and post-nasal EPAP means ± standard deviations (M ± SD) for apnea-hypopnea index (AHI) in 345 patients decreased from 27.32 ± 22.24 to 12.78 ± 16.89 events/hr (relative reduction = 53...
2015: Sleep Disorders
https://www.readbyqxmd.com/read/26653187/the-evolution-of-the-provent-score-from-medical-to-surgical-applications
#6
EDITORIAL
Christopher E Cox, Shannon S Carson
No abstract text is available yet for this article.
December 2015: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/26528705/a-phase-i-trial-of-high-dose-chemotherapy-combining-topotecan-plus-cyclophosphamide-with-hematopoietic-stem-cell-transplantation-for-ovarian-cancer-the-itov-01bis-study
#7
Frédéric Selle, Patricia Pautier, Catherine Lhommé, Patrice Viens, Michel Fabbro, François Lokiec, Joseph Gligorov, Sandrine Richard, Stéphane Provent, Daniele G Soares, Jean-Pierre Lotz
BACKGROUND: Dose-intensive chemotherapy with hematopoietic stem cell transplantation has been evaluated as a salvage treatment for recurrent ovarian cancer, but its benefit has not yet been demonstrated. In a previous phase I trial, we reported the feasibility of administering topotecan as a salvage regimen. METHODS: Twenty-one patients were treated with escalating doses of topotecan associated with a fixed dose of cyclophosphamide. RESULTS: The maximum tolerated dose was established at 9...
2016: Chemotherapy
https://www.readbyqxmd.com/read/26418231/validation-and-extension-of-the-prolonged-mechanical-ventilation-prognostic-model-provent-score-for-predicting-1-year-mortality-after-prolonged-mechanical-ventilation
#8
Chiedozie I Udeh, Brent Hadder, Belinda L Udeh
RATIONALE: Prognostic models can inform management decisions for patients requiring prolonged mechanical ventilation. The Prolonged Mechanical Ventilation Prognostic model (ProVent) score was developed to predict 1-year mortality in these patients. External evaluation of such models is needed before they are adopted for routine use. OBJECTIVES: The goal was to perform an independent external validation of the modified ProVent score and assess for spectrum extension at 14 days of mechanical ventilation...
December 2015: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/26247337/development-and-validation-of-a-mortality-prediction-model-for-patients-receiving-14-days-of-mechanical-ventilation
#9
MULTICENTER STUDY
Catherine L Hough, Ellen S Caldwell, Christopher E Cox, Ivor S Douglas, Jeremy M Kahn, Douglas B White, Eric J Seeley, Shrikant I Bangdiwala, Gordon D Rubenfeld, Derek C Angus, Shannon S Carson
OBJECTIVES: The existing risk prediction model for patients requiring prolonged mechanical ventilation is not applicable until after 21 days of mechanical ventilation. We sought to develop and validate a mortality prediction model for patients earlier in the ICU course using data from day 14 of mechanical ventilation. DESIGN: Multicenter retrospective cohort study. SETTING: Forty medical centers across the United States. PATIENTS: Adult patients receiving at least 14 days of mechanical ventilation...
November 2015: Critical Care Medicine
https://www.readbyqxmd.com/read/26206262/bodipy-a-highly-versatile-platform-for-the-design-of-bimodal-imaging-probes
#10
Damien Lhenry, Manuel Larrouy, Claire Bernhard, Victor Goncalves, Olivier Raguin, Peggy Provent, Mathieu Moreau, Bertrand Collin, Alexandra Oudot, Jean-Marc Vrigneaud, François Brunotte, Christine Goze, Franck Denat
In molecular imaging, multimodal imaging agents can provide complementary information, for improving the accuracy of disease diagnosis or enhancing patient management. In particular, optical/nuclear imaging may find important preclinical and clinical applications. To simplify the preparation of dual-labeled imaging agents, we prepared versatile monomolecular multimodal imaging probe (MOMIP) platforms containing both a fluorescent dye (BODIPY) and a metal chelator (polyazamacrocycle). One of the MOMIP was conjugated to a cyclopeptide (i...
September 7, 2015: Chemistry: a European Journal
https://www.readbyqxmd.com/read/26169543/mortality-in-chronically-critically-ill-patients-expanding-the-use-of-the-provent-score
#11
Márcio Manozzo Boniatti, Andreia Della Giustina, Luiz Gustavo Marin, Josiane França, Moreno Calcagnotto Dos Santos, Josi Vidart, José Augusto Santos Pellegrini, Carla Silva Lincho, Edison Moraes Rodrigues Filho
PURPOSE: The purpose of the study is to look at the performance of the Prognosis for Prolonged Ventilation (ProVent) score with a short-term outcome as well as when used earlier during the course of prolonged mechanical ventilation (MV). MATERIALS AND METHODS: This retrospective study was performed in a tertiary public hospital from August 2011 to August 2012. All patients admitted to the intensive care unit (ICU) during this period were included in the study. Chronically critically ill (CCI) patients were defined as those with 21 days of MV...
October 2015: Journal of Critical Care
https://www.readbyqxmd.com/read/25891298/provent-therapy-for-obstructive-sleep-apnea-impact-of-nasal-obstruction
#12
Michael Friedman, Michelle S Hwang, Sreeya Yalamanchali, Thomas Pott, Mandeep Sidhu, Ninos J Joseph
OBJECTIVES/HYPOTHESIS: Determine the impact of nasal obstruction on efficacy, success, and adherence of Provent therapy in patients with obstructive sleep apnea (OSA). STUDY DESIGN: Prospective, two-arm, clinical pilot study at a single clinical site. METHODS: Patients with OSA who failed continuous positive airway pressure therapy were divided into two treatment arms: arm 1 were patients with no complaints of nasal obstruction and <50% nasal obstruction on exam, and arm 2 were patients with occasional complaints of nasal obstruction and 50% to 80% nasal obstruction on exam...
January 2016: Laryngoscope
https://www.readbyqxmd.com/read/25852965/development-and-usability-testing-of-a-web-based-decision-aid-for-families-of-patients-receiving-prolonged-mechanical-ventilation
#13
Christopher E Cox, Nicholas G Wysham, Brenda Walton, Derek Jones, Brian Cass, Maria Tobin, Mattias Jonsson, Jeremy M Kahn, Douglas B White, Catherine L Hough, Carmen L Lewis, Shannon S Carson
BACKGROUND: Web-based decision aids are increasingly important in medical research and clinical care. However, few have been studied in an intensive care unit setting. The objectives of this study were to develop a Web-based decision aid for family members of patients receiving prolonged mechanical ventilation and to evaluate its usability and acceptability. METHODS: Using an iterative process involving 48 critical illness survivors, family surrogate decision makers, and intensivists, we developed a Web-based decision aid addressing goals of care preferences for surrogate decision makers of patients with prolonged mechanical ventilation that could be either administered by study staff or completed independently by family members (Development Phase)...
2015: Annals of Intensive Care
https://www.readbyqxmd.com/read/25673137/the-provent-model-learns-to-speak-french
#14
COMMENT
Christopher E Cox
Leroy and colleagues report on the accuracy of the Prolonged Mechanical Ventilation Prognostic Model ('ProVent') in a cohort study of patients ventilated for at least 21 days in one of three hospitals in the north of France. This study is noteworthy because it is the first to describe the performance of the ProVent model both outside the US and in a community hospital-based setting.
2014: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/25493378/intensive-chemotherapy-as-salvage-treatment-for-solid-tumors-focus-on-germ-cell-cancer
#15
F Selle, J Gligorov, S Richard, A Khalil, I Alexandre, D Avenin, S Provent, D G Soares, J P Lotz
Germ cell tumors present contrasting biological and molecular features compared to many solid tumors, which may partially explain their unusual sensitivity to chemotherapy. Reduced DNA repair capacity and enhanced induction of apoptosis appear to be key factors in the sensitivity of germ cell tumors to cisplatin. Despite substantial cure rates, some patients relapse and subsequently die of their disease. Intensive doses of chemotherapy are used to counter mechanisms of drug resistance. So far, high-dose chemotherapy with hematopoietic stem cell support for solid tumors is used only in the setting of testicular germ cell tumors...
January 2015: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/25389784/sensitivity-and-specificity-of-hypopnoea-detection-using-nasal-pressure-in-the-presence-of-a-nasal-expiratory-resistive-device-provent%C3%A2
#16
Stephen Milne, Terence C Amis, John R Wheatley, Kristina Kairaitis
Nasal expiratory resistive valves (Provent(®)) have been proposed as novel therapy for obstructive sleep apnea. We compared pressure measurements from a standard nasal pressure catheter used to assess nasal airflow during sleep with those from nasal expiratory resistive device with attached proprietary nasal pressure cannula. Nasal pressure cannula or Provent(®) + proprietary nasal pressure cannula were attached to a bench model of human anterior nares and nasal passages, and pressure measured (P). Respiratory airflows generated by a subject breathing were applied to rear of model and airflow (V) measured via pneumotachograph...
December 2014: Physiological Measurement
https://www.readbyqxmd.com/read/25377018/the-epidemiology-of-chronic-critical-illness-in-the-united-states
#17
Jeremy M Kahn, Tri Le, Derek C Angus, Christopher E Cox, Catherine L Hough, Douglas B White, Sachin Yende, Shannon S Carson
OBJECTIVES: The epidemiology of chronic critical illness is not well characterized. We sought to determine the prevalence, outcomes, and associated costs of chronic critical illness in the United States. DESIGN: Population-based cohort study using data from the United States Healthcare Costs and Utilization Project from 2004 to 2009. SETTING: Acute care hospitals in Massachusetts, North Carolina, Nebraska, New York, and Washington. PATIENTS: Adult and pediatric patients meeting a consensus-derived definition for chronic critical illness, which included one of six eligible clinical conditions (prolonged acute mechanical ventilation, tracheotomy, stroke, traumatic brain injury, sepsis, or severe wounds) plus at least 8 days in an ICU...
February 2015: Critical Care Medicine
https://www.readbyqxmd.com/read/25372715/intensive-chemotherapy-as-salvage-treatment-for-solid-tumors-focus-on-germ-cell-cancer
#18
F Selle, J Gligorov, S Richard, A Khalil, I Alexandre, D Avenin, S Provent, D G Soares, J P Lotz
Germ cell tumors present contrasting biological and molecular features compared to many solid tumors, which may partially explain their unusual sensitivity to chemotherapy. Reduced DNA repair capacity and enhanced induction of apoptosis appear to be key factors in the sensitivity of germ cell tumors to cisplatin. Despite substantial cure rates, some patients relapse and subsequently die of their disease. Intensive doses of chemotherapy are used to counter mechanisms of drug resistance. So far, high-dose chemotherapy with hematopoietic stem cell support for solid tumors is used only in the setting of testicular germ cell tumors...
November 4, 2014: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/25353107/new-therapies-for-obstructive-sleep-apnea
#19
REVIEW
David P White
A strong demand for new obstructive sleep apnea (OSA) therapies exists and several are emerging. Hypoglossal nerve stimulation is designed to activate upper airway muscles. The initial study from Inspire (Maple Grove, MN) suggests that the device will work well in a very selective group of OSA patients. However, it is likely to be quite expensive. The Winx device (ApniCure, Redwood City, CA) works by establishing a vacuum in the oral cavity, which pulls the uvula and soft palate forward and stabilizes the tongue position...
October 2014: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/25037939/one-year-mortality-in-patients-requiring-prolonged-mechanical-ventilation-multicenter-evaluation-of-the-provent-score
#20
MULTICENTER STUDY
Guillaume Leroy, Patrick Devos, Fabien Lambiotte, Didier Thévenin, Olivier Leroy
INTRODUCTION: Current severity-of-illness indexes are unable to assess the long-term prognosis of patients requiring prolonged mechanical ventilation. A prognostic scoring system (Prognosis for Prolonged Ventilation score - ProVent - score) seems able to evaluate one-year mortality of such patients. However, testing of the model outside the developers' centers has not been reported. So, it is unclear how the ProVent score performs in non-US and non-tertiary ICUs. The goal of our study was to evaluate its performances in a French multicenter, community hospital-based setting...
2014: Critical Care: the Official Journal of the Critical Care Forum
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