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https://www.readbyqxmd.com/read/28228766/cell-wall-remodeling-in-abscission-zone-cells-during-ethylene-promoted-fruit-abscission-in-citrus
#1
Paz Merelo, Javier Agustí, Vicent Arbona, Mário L Costa, Leandro H Estornell, Aurelio Gómez-Cadenas, Silvia Coimbra, María D Gómez, Miguel A Pérez-Amador, Concha Domingo, Manuel Talón, Francisco R Tadeo
Abscission is a cell separation process by which plants can shed organs such as fruits, leaves, or flowers. The process takes place in specific locations termed abscission zones. In fruit crops like citrus, fruit abscission represents a high percentage of annual yield losses. Thus, understanding the molecular regulation of abscission is of capital relevance to control production. To identify genes preferentially expressed within the citrus fruit abscission zone (AZ-C), we performed a comparative transcriptomics assay at the cell type resolution level between the AZ-C and adjacent fruit rind cells (non-abscising tissue) during ethylene-promoted abscission...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28227503/suitability-of-nitinol-electrodes-in-neural-prostheses-such-as-endovascular-neural-interfaces
#2
Yan T Wong, Nicholas L Opie, Sam E John, Giulia Gerboni, Gil S Rind, Stephen M Ronayne, Kate E Fox, Thomas J Oxley, David B Grayden, Yan T Wong, Nicholas L Opie, Sam E John, Giulia Gerboni, Gil S Rind, Stephen M Ronayne, Kate E Fox, Thomas J Oxley, David B Grayden, Sam E John, Stephen M Ronayne, David B Grayden, Nicholas L Opie, Kate E Fox, Giulia Gerboni, Thomas J Oxley, Yan T Wong, Gil S Rind
A major challenge facing neural prostheses is the development of electrodes that are well tolerated by the brain and body. A novel way to circumvent the need to perform an invasive craniotomy and penetration of the blood-brain barrier to implant electrodes, is to guide electrodes up into the cerebral veins and place electrodes on the vessel walls adjacent to neuronal populations. To aid in the development of these stent based devices, microelectrodes manufactured from Nitinol would allow electrodes to be implanted via a catheter and then once deployed, alter their shape to conform to the vessel walls...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227501/feasibility-of-a-chronic-minimally-invasive-endovascular-neural-interface
#3
Nicholas L Opie, Gil S Rind, Sam E John, Stephen M Ronayne, David B Grayden, Anthony N Burkitt, Clive N May, Terence J O'Brien, Thomas J Oxley, Nicholas L Opie, Gil S Rind, Sam E John, Stephen M Ronayne, David B Grayden, Anthony N Burkitt, Clive N May, Terence J O'Brien, Thomas J Oxley, Sam E John, Stephen M Ronayne, David B Grayden, Nicholas L Opie, Anthony N Burkitt, Terence J O'Brien, Clive N May, Thomas J Oxley, Gil S Rind
Development of a neural interface that can be implanted without risky, open brain surgery will increase the safety and viability of chronic neural recording arrays. We have developed a minimally invasive surgical procedure and an endovascular electrode-array that can be delivered to overlie the cortex through blood vessels. Here, we describe feasibility of the endovascular interface through electrode viability, recording potential and safety. Electrochemical impedance spectroscopy demonstrated that electrode impedance was stable over 91 days and low frequency phase could be used to infer electrode incorporation into the vessel wall...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28213018/pathogen-biofilm-formation-on-cantaloupe-surface-and-its-impact-on-the-antibacterial-effect-of-lauroyl-arginate-ethyl
#4
Yezhi Fu, Amanda J Deering, Arun K Bhunia, Yuan Yao
Pathogen biofilm at fruit surface may pose a particular risk to food safety. In this study, the biofilms of Listeria monocytogenes V7 and Salmonella enterica serovar Typhimurium ATCC 13311 on cantaloupe fruit surface were visualized, and the resistance of biofilms against lauroyl arginate ethyl (LAE, an antibacterial compound) was evaluated. Each bacterium was inoculated on isolated cantaloupe rind surfaces at 10(5)-10(6) CFU/cm(2) and after incubation for 2, 12, 24, and 48 h, the surfaces were imaged using cryo-scanning electron microscopy (Cryo-SEM)...
June 2017: Food Microbiology
https://www.readbyqxmd.com/read/28211296/recommendations-for-the-medical-management-of-chronic-venous-disease-the-role-of-micronized-purified-flavanoid-fraction-mpff
#5
Ronald Bush, Anthony Comerota, Mark Meissner, Joseph D Raffetto, Steven R Hahn, Katherine Freeman
Scope A systematic review of the clinical literature concerning medical management of chronic venous disease with the venoactive therapy Micronized Purified Flavonoid Fraction was conducted in addition to an investigation of the hemodynamics and mechanism of chronic venous disease. Methods The systematic review of the literature focused on the use of Micronized Purified Flavonoid Fraction (diosmin) which has recently become available in the US, in the management of chronic venous disease. The primary goal was to assess the level of evidence of the role of Micronized Purified Flavonoid Fraction in the healing of ulcers, and secondarily on the improvement of the symptoms of chronic venous disease such as edema...
April 2017: Phlebology
https://www.readbyqxmd.com/read/28192137/a-strategic-approach-for-direct-recovery-and-stabilization-of-fusarium-sp-ict-sac1-cutinase-from-solid-state-fermented-broth-by-carrier-free-cross-linked-enzyme-aggregates
#6
Sandeep A Chaudhari, Rekha S Singhal
The major hurdles in commercial exploitation of cutinase (having both esterolytic and lipolytic activities) with potent industrial applications are its high production cost, operational instability and reusability. Although commercially available in immobilized form, its immobilization process (synthesis of support/carrier) makes it expensive. Herein we tried to address multiple issues of production cost, stability, and reusability, associated with cutinase. Waste watermelon rinds, an agroindustrial waste was considered as a cheap support for solid state fermentation (SSF) for cutinase production by newly isolated Fusarium sp...
February 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28190542/principles-of-effective-communication-with-patients-who-have-intellectual-disability-among-primary-care-physicians
#7
S Werner, S Yalon-Chamovitz, M Tenne Rinde, A D Heymann
OBJECTIVE: Examine physicians' implementation of effective communication principles with patients with intellectual disabilities (ID) and its predictors. METHODS: Focus groups helped construct a quantitative questionnaire. The questionnaire (completed by 440 physicians) examined utilization of effective communication principles, attitudes toward individuals with ID, subjective knowledge and number of patients with ID. RESULTS: Subjective knowledge of ID and more patients with ID increased utilization of effective communication principles...
February 2, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28176141/myocardial-infarction-and-future-risk-of-cancer-in-the-general-population-the-troms%C3%A3-study
#8
Ludvig B Rinde, Birgit Småbrekke, Erin M Hald, Ellen E Brodin, Inger Njølstad, Ellisiv B Mathiesen, Maja-Lisa Løchen, Tom Wilsgaard, Sigrid K Brækkan, Anders Vik, John-Bjarne Hansen
The association between myocardial infarction (MI) and future risk of incident cancer is scarcely investigated. Therefore, we aimed to study the risk of cancer after a first time MI in a large cohort recruited from a general population. Participants in a large population-based study without a previous history of MI or cancer (n = 28,763) were included and followed from baseline to date of cancer, death, migration or study end. Crude incidence rates (IRs) and hazard ratios (HRs) for cancer after MI were calculated...
February 7, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28173798/spasmogenic-and-spasmolytic-activity-of-rind-of-punica-granatum-linn
#9
Niaz Ali, Ayesha Jamil, Syed Wadood Ali Shah, Ismail Shah, Ghayour Ahmed
BACKGROUND: Rind of Punica granatum is traditionally used in treatment of abdominal cramps and various GIT disorders. So far spasmolytic activity of rind of Punica granatum has been reported using in vitro model. However, its mode of action is not explored yet. Therefore, the current work describes the possible mode of action for spasmolytic activity of methanolic extract of rind of Punica granatum (Pg. Cr). Acute toxicity study is also performed to determine its safe dose range. METHODS: Rind of Punica granatum was subjected to shade drying...
February 7, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28169002/the-c8-side-chain-is-one-of-the-key-functional-group-of-garcinol-for-its-anti-cancer-effects
#10
Xin-Ying Zhou, Jing Cao, Chao-Ming Han, Shu-Wen Li, Chen Zhang, Yin-Duan Du, Qian-Qian Zhou, Xin-Yan Zhang, Xin Chen
Garcinol from the fruit rind of Garcinia indica shows anti-carcinogenic and anti-inflammatory properties, but its mechanism and key functional groups were still need to be identified. Our previous computer modeling suggested that the C8 side chain of Garcinol is so large that it may influence the bioactivity of the compound. 8-Me Garcinol, a derivative of Garcinol in which the bulky side chain at the C8 position of Garcinol is replaced with a much smaller methyl group, was synthesized through a 12-step procedure starting from 1,3-cyclohexanedione...
January 22, 2017: Bioorganic Chemistry
https://www.readbyqxmd.com/read/28129739/itraq-based-protein-profiling-and-fruit-quality-changes-at-different-development-stages-of-oriental-melon
#11
Xiaoou Guo, Jingjing Xu, Xiaohui Cui, Hao Chen, Hongyan Qi
BACKGROUND: Oriental melon is one of the most popular crops for its nutritional and flavour quality. Components that determine melon quality, such as sugar, colour, texture, flavour and aroma, among other factors, accumulate in different developmental stages. Thus, correlating the proteomic profiles with the biochemical and physiological changes occurring in the oriental melon is very important for advancing our understanding of oriental melon quality in the ripening processes. RESULTS: iTRAQ-based protein profiling was conducted on 'YuMeiren' oriental melon fruit at different developmental stages...
January 28, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28100189/an-snp-based-saturated-genetic-map-and-qtl-analysis-of-fruit-related-traits-in-zucchini-using-genotyping-by-sequencing
#12
Javier Montero-Pau, José Blanca, Cristina Esteras, Eva Ma Martínez-Pérez, Pedro Gómez, Antonio J Monforte, Joaquín Cañizares, Belén Picó
BACKGROUND: Cucurbita pepo is a cucurbit with growing economic importance worldwide. Zucchini morphotype is the most important within this highly variable species. Recently, transcriptome and Simple Sequence Repeat (SSR)- and Single Nucleotide Polymorphism (SNP)-based medium density maps have been reported, however further genomic tools are needed for efficient molecular breeding in the species. Our objective is to combine currently available complete transcriptomes and the Zucchini genome sequence with high throughput genotyping methods, mapping population development and extensive phenotyping to facilitate the advance of genomic research in this species...
January 18, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28047707/su-g-201-14-is-maximum-skin-dose-a-reliable-metric-for-accelerated-partial-breast-irradiation-with-brachytherapy
#13
S Park, O Ragab, S Patel, Y Kim, J Demanes, M Kamrava
PURPOSE: To evaluate the reliability of the maximum point dose (Dmax) to the skin surface as a dosimetric constraint, we investigated the correlation between Dmax at the skin surface and dose metrics at various definitions of skin thickness. METHODS: 42 patients treated with APBI using a Strut Adjusted Volume Implant (SAVI) applicator between 2010 and 2014 were retrospectively reviewed. Target (PTV_EVAL) and organs at risk (OARs: skin, lung, and ribs) were delineated on a CT following NSABP B-39 guidelines...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043333/a-nematicidal-tannin-from-punica-granatum-l-rind-and-its-physiological-effect-on-pine-wood-nematode-bursaphelenchus-xylophilus
#14
Qunqun Guo, Guicai Du, Hongtao Qi, Yanan Zhang, Tongqing Yue, Jingchao Wang, Ronggui Li
The ethanol extract of Punica granatum L. rind was tested to show significant nematicidal activity against pine wood nematode. Three nematicidal compounds were obtained from the ethanol extract by bioassay-guided fractionation and identified as punicalagin 1, punicalin 2, and corilagin 3 by mass and nuclear magnetic resonance spectral data analysis. Punicalagin 1 was most active against PWN among the purified compounds with the LC50 value of 307.08μM in 72h. According to the enzyme assays in vitro, punicalagin 1 could inhibit the activity of acetylcholinesterase, amylase and cellulase from PWN with IC50 value of 0...
January 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28031235/htp-nutraceutical-screening-for-histone-deacetylase-inhibitors-and-effects-of-hdacis-on-tumor-suppressing-mirnas-by-trichostatin-a-and-grapeseed-vitis-vinifera-in-hela-cells
#15
Elizabeth A Mazzio, Karam F A Soliman
BACKGROUND/AIM: Aggressive tumor malignancies are a consequence of delayed diagnosis, epigenetic/phenotype changes and chemo-radiation resistance. Histone deacetylases (HDACs) are a major epigenetic regulator of transcriptional repression, which are highly overexpressed in advanced malignancy. While original chemotherapy drugs were modeled after phytochemicals elucidated by botanical screenings, HDAC inhibitors (HDACi) such as apicidin, trichostatin A (TSA) and butyrate were discovered as products of fungus and microbes, in particular, gut microbiota...
2, 2017: Cancer Genomics & Proteomics
https://www.readbyqxmd.com/read/28028308/metastatic-squamous-cell-carcinoma-of-the-pleura-a-rare-complication-of-hidradenitis-suppurativa
#16
Kiran Joglekar, Christopher Jackson, Dipen Kadaria, Amik Sodhi
BACKGROUND Squamous cell carcinoma (SCC), also known as Marjolin ulcer, is a rare complication of hidradenitis suppurativa (HS). Metastatic SCC from HS typically involves the axial skeleton or abdominopelvic viscera. Metastatic disease to the lungs is a rare phenomenon with only three reported cases of lung parenchyma. We present a biopsy proven case of metastatic SCC to the pleura from gluteal HS. CASE REPORT A 46-year-old male with a history of recently diagnosed Marjolin ulcer secondary to gluteal HS was transferred to our intensive care unit for acute hypoxemic respiratory failure secondary to recurrent pleural effusion...
December 28, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27991775/a-new-approach-to-sampling-intact-fe-plaque-reveals-si-induced-changes-in-fe-mineral-composition-and-shoot-as-in-rice
#17
Douglas C Amaral, Guilherme Lopes, Luiz R G Guilherme, Angelia L Seyfferth
The Fe (oxyhydr)oxide rind, or Fe plaque, that forms on aquatic plant roots is an important sorbent of metal(loid)s and plays a role in the attenuation of metal(loid) uptake into higher plants. However, the mineral composition of Fe plaque and thus its potential to sorb metal(loid)s is affected by solution chemistry. The predominant strategy to characterize Fe plaque using dithionite-citrate-bicarbonate (DCB) extraction and elemental analysis reveals total Fe quantity but misses the mineral structure of the Fe (oxyhydr)oxide...
January 3, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/27943588/separation-of-phenolic-acids-from-sugarcane-rind-by-online-solid-phase-extraction-with-high-speed-counter-current-chromatography
#18
Ping Geng, Yingtong Fang, Ronglong Xie, Weilun Hu, Xingjun Xi, Qiao Chu, Genlai Dong, Nusrat Shaheen, Yun Wei
Sugarcane rind contains some functional phenolic acids. The separation of these compounds from sugarcane rind is able to realize the integrated utilization of the crop and reduce environment pollution. In this paper, a novel protocol based on interfacing online solid-phase extraction with high-speed counter-current chromatography (HSCCC) was established, aiming at improving and simplifying the process of phenolic acids separation from sugarcane rind. The conditions of online solid-phase extraction with HSCCC involving solvent system, flow rate of mobile phase as well as saturated extent of absorption of solid-phase extraction were optimized to improve extraction efficiency and reduce separation time...
December 12, 2016: Journal of Separation Science
https://www.readbyqxmd.com/read/27889144/exploring-the-microbiota-of-the-red-brown-defect-in-smear-ripened-cheese-by-454-pyrosequencing-and-its-prevention-using-different-cleaning-systems
#19
Raffaele Guzzon, Ilaria Carafa, Kieran Tuohy, Gonzalo Cervantes, Luca Vernetti, Andrea Barmaz, Roberto Larcher, Elena Franciosi
Red-brown pigmentation can occasionally form in smeared-ripened cheese such as Fontina during the ripening process. This reaction is due to over-development of the typical microbiota present on the rind. Previous studies have demonstrated the relationship between red-brown pigmentation and the traditional utilization of wooden shelves during cheese ripening. The first part of the paper focuses on the characterisation of yeast and bacterial microbiota: plate counts and 454-pyrosequencing were performed in spoiled (n = 6) and non-spoiled cheeses (n = 6) and on the wooden shelves used during ripening...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27886374/effect-of-different-aloe-fractions-on-the-growth-of-lactic-acid-bacteria
#20
Giulia Chiodelli, Marco Pellizzoni, Gabriela Ruzickova, Luigi Lucini
Several foods on the market, such as yogurt and fermented milk, include mixtures of prebiotics and probiotic microorganisms effective in promoting the proliferation and equilibrium of intestinal bacteria, thus improving gut health. Particularly, researchers and the public have shown increasing interest in the combination of probiotics with natural substances that promote health or that can act as substrates to promote bacterial growth. The aim of this study is to evaluate the effects of different extracts of Aloe barbadensis and Aloe arborescens in fermented milk, taking into account both the prebiotic effect of aloe polysaccharides and the antimicrobial activity of several secondary metabolites...
January 2017: Journal of Food Science
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