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https://www.readbyqxmd.com/read/28717883/first-postpubertal-male-same-sex-sexual-experience-in-the-national-health-and-social-life-survey-current-functioning-in-relation-to-age-at-time-of-experience-and-partner-age
#1
Bruce Rind
This study used an important data set to examine long-term adjustment and functioning in men, who as adolescents had sexual experiences with men. The data came from the National Health and Social Life Survey, which used a national probability sample (Laumann, Gagnon, Michael, & Michaels, 1994). Three perspectives were considered, which offered different predictions. From the "child sexual abuse" (CSA) paradigm, which dominates clinical, legal, and lay views, expected was robust evidence for poorer adjustment, given that intense harm is assumed to be intrinsic...
July 17, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28708030/growth-kinetics-of-listeria-monocytogenes-in-cut-produce
#2
Joelle K Salazar, Surasri N Sahu, Ian M Hildebrandt, Lijie Zhang, Yan Qi, Girvin Liggans, Atin R Datta, Mary Lou Tortorello
Cut produce continues to constitute a significant portion of the fresh fruit and vegetables sold directly to consumers. As such, the safety of these items during storage, handling, and display remains a concern. Cut tomatoes, cut leafy greens, and cut melons, which have been studied in relation to their ability to support pathogen growth, have been specifically identified as needing temperature control for safety. Data are needed on the growth behavior of foodborne pathogens in other types of cut produce items that are commonly offered for retail purchase and are potentially held without temperature control...
July 14, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28669782/the-drosophila-melanogaster-tribbles-pseudokinase-is-necessary-for-proper-memory-formation
#3
Holly LaFerriere, Troy Zars
The tribbles (trbl) pseudokinases play important roles in signaling and physiology in multiple contexts, ranging from innate immunity to cancer, suggesting fundamental cellular functions for the trbls' gene products. Despite expression of the trbl pseudokinases in the nervous systems of invertebrate and vertebrate animals, and evidence that they have a function within mouse and human dopamine neurons, there is no clear case for a function of a Trbl protein that influences behavior. Indeed, the first and only evidence for this type of function comes from Drosophila melanogaster, where a mutation of the single trbl gene was identified in a genetic screen for short-term memory mutant flies...
June 29, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28665969/potentiated-virucidal-activity-of-pomegranate-rind-extract-pre-and-punicalagin-against-herpes-simplex-virus-hsv-when-co-administered-with-zinc-ii-ions-and-antiviral-activity-of-pre-against-hsv-and-aciclovir-resistant-hsv
#4
David M J Houston, Joachim J Bugert, Stephen P Denyer, Charles M Heard
BACKGROUND: There is a clinical need for new therapeutic products against Herpes simplex virus (HSV). The pomegranate, fruit of the tree Punica granatum L, has since ancient times been linked to activity against infection. This work probed the activity of pomegranate rind extract (PRE) and co-administered zinc (II) ions. MATERIALS AND METHODS: PRE was used in conjunction with zinc (II) salts to challenge HSV-1 and aciclovir-resistant HSV in terms of virucidal plaque assay reduction and antiviral activities in epithelial Vero host cells...
2017: PloS One
https://www.readbyqxmd.com/read/28644126/extensive-horizontal-gene-transfer-in-cheese-associated-bacteria
#5
Kevin S Bonham, Benjamin E Wolfe, Rachel J Dutton
Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments. Identifying widespread HGT regions within multispecies microbiomes can pinpoint the molecular mechanisms that play key roles in microbiome assembly. We sought to identify horizontally transferred genes within a model microbiome, the cheese rind. Comparing 31 newly-sequenced and 134 previously sequenced bacterial isolates from cheese rinds, we identified over 200 putative horizontally transferred genomic regions containing 4,844 protein coding genes...
June 23, 2017: ELife
https://www.readbyqxmd.com/read/28636136/capillary-zone-electrophorsis-for-the-analysis-of-naturally-occurring-2-hydroxycitric-acids-and-their-lactones
#6
B L Abhijith, Moolya Mohan, David Joseph, Simimole Haleema, Hassan Y Aboul-Enein, Ibrahim Ibnusaud
A simple capillary zone electrophoresis method with direct ultraviolet detection has been developed for the analysis of naturally occurring diastereomeric 2-hydroxycitric acid lactones. Using 50 mM sodium phosphate buffer of pH 7, a baseline resolution Rs > 3.0 was observed for all organic acids selected for the present study. This method was employed for the quantitative determination of title acids present in the plant sources namely G. cambogia fruit rinds and H. sabdariffa calyx. Conversion of 2-hydroxycitric acids to their lactones on heating above plant sources is deliberated...
June 21, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28627966/further-evidence-of-cucurbit-host-specificity-among-acidovorax-citrulli-groups-based-on-a-detached-melon-fruit-pathogenicity-assay
#7
Lichun Yan, Hu Baishi, Gong Chen, Mei Zhao, Ron Ricardo Walcott
Bacterial fruit blotch (BFB), caused by the gram-negative bacterium Acidovorax citrulli, is a serious economic threat to cucurbit crop production worldwide. A. citrulli strains can be divided into two genetically distinct groups with group I strains infecting a range of cucurbit species, and group II strains being predominantly associated with watermelon. Group I and II A. citrulli strains differ in their arsenal of type III secreted (T3S) effector proteins and we hypothesize that these effectors are critical for cucurbit host preference...
June 19, 2017: Phytopathology
https://www.readbyqxmd.com/read/28597428/mapping-quantitative-trait-loci-for-fruit-traits-and-powdery-mildew-resistance-in-melon-cucumis-melo
#8
Yu-Hua Wang, Dong-Hong Wu, Jin-Hsing Huang, Shing-Jy Tsao, Kae-Kang Hwu, Hsiao-Feng Lo
BACKGROUND: Fruit characters affect consumer preferences and the market value of melons is determined by fruit quality. Most fruit quality-related traits are controlled by multiple genes, and are influenced by environmental factors. Furthermore, powdery mildew is another limiting factor in melon production. To develop new melon cultivars with disease resistance and high quality fruits using the molecular marker-assisted breeding strategy, identification of quantitative trait loci for fruit quality and disease resistance is required...
December 2016: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/28595827/the-ovine-motor-cortex-a-review-of-functional-mapping-and-cytoarchitecture
#9
REVIEW
Sam E John, Timothy J H Lovell, Nicholas L Opie, Stefan Wilson, Theodore C Scordas, Yan T Wong, Gil S Rind, Stephen Ronayne, Sébastien H Bauquier, Clive N May, David B Grayden, Terence J O'Brien, Thomas J Oxley
In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological research due to their relatively large brain and blood vessel size, their cortical architecture, and their docile temperament. However, the functional anatomy of sheep brain is not as well studied as that of non-human primates, rodents, and felines. For example, while the location of the sheep motor cortex has been known for many years, there have been few studies of the somatotopy of the motor cortex and there were a range of discrepancies across them...
June 16, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28593516/antidepressant-and-anxiolytic-effects-of-garcinia-indica-fruit-rind-via-monoaminergic-pathway
#10
Isha Dhamija, Milind Parle, Sandeep Kumar
Depression and anxiety are the most crippling neuropsychiatric disorders of this modern era. These mostly occur as anxiety followed by depression or in mixed state. Therefore, there is an urgent need of a safe and effective treatment, which proves its worth in this ailment. What else than a conventional food would be a better choice for a convenient therapy. Therefore, Garcinia indica, commonly known as Kokam, fruit rind has been used in the present study to investigate its antidepressant and anti-anxiety potential using forced swim test, tail suspension test, and reserpine-induced hypothermia; and elevated plus maze, hole-board test, and light dark model, respectively...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28573253/in-vivo-carbon-tetrachloride-induced-hepatoprotective-and-in-vitro-cytotoxic-activities-of-garcinia-hombroniana-seashore-mangosteen
#11
Nargis Jamila, Naeem Khan, Amir Atlas Khan, Imran Khan, Sadiq Noor Khan, Zainal Amiruddin Zakaria, Melati Khairuddean, Hasnah Osman, Kyong Su Kim
BACKGROUND: Garcinia hombroniana, known as "manggis hutan" (jungle mangosteen) in Malaysia, is distributed in tropical Asia, Borneo, Thailand, Andaman, Nicobar Islands, Vietnam and India. In Malaysia, its ripened crimson sour fruit rind is used as a seasoning agent in curries and culinary dishes. Its roots and leaves decoction is used against skin infections and after child birth. This study aimed to evaluate in vivo hepatoprotective and in vitro cytotoxic activities of 20% methanolic ethyl acetate (MEA) G...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28552725/the-inhibitory-effect-of-anti-tumor-polysaccharide-from-punica-granatum-on-metastasis
#12
Sheeja Varghese, Manu M Joseph, Aravind S R, Unnikrishnan B S, T T Sreelekha
Galactomannan (PSP001) isolated from the fruit rind of Punica granatum was demonstrated as an excellent antioxidant, immunomodulatory and anticancer agent both in vitro and in vivo models. Since the most lethal and debilitating attribute of cancer cells is their ability to evolve to a state of malignancy, with key features like increased angiogenesis, invasion, migration, colony formation, and metastasis, the present study focused on evaluating the effects of the galactomannan on tumor and malignancy. PSP001 effectively reduced the neovascularization in chick embryos highlighting its potential as an angiogenic inhibitor...
May 25, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28551185/crystallization-and-demineralization-phenomena-in-stabilized-white-mold-cheese
#13
Gil F Tansman, Paul S Kindstedt, John M Hughes
Stabilized white mold cheese is a commercially important variant of traditional white mold cheese (sometimes called bloomy rind cheese) that has an extended shelf life compared with the traditional permutation. The objectives of this observational study were to document mineral element movements and the development of a pH gradient in stabilized white mold cheese, and to use novel crystallographic techniques to identify crystals that form in the rind of this cheese. Cheeses from 3 separate batches were collected from a commercial supplier at d 1, 4, 10, 14, and 18 of aging and analyzed in a randomized block design...
May 24, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28529184/the-grade-working-group-clarifies-the-construct-of-certainty-of-evidence
#14
Monica Hultcrantz, David Rind, Elie A Akl, Shaun Treweek, Reem A Mustafa, Alfonso Iorio, Brian S Alper, Joerg J Meerpohl, M Hassan Murad, Mohammed T Ansari, Srinivasa Vittal Katikireddi, Pernilla Östlund, Sofia Tranæus, Robin Christensen, Gerald Gartlehner, Jan Brozek, Ariel Izcovich, Holger Schünemann, Gordon Guyatt
OBJECTIVE: To clarify the GRADE (grading of recommendations assessment, development and evaluation) definition of certainty of evidence and suggest possible approaches to rating certainty of the evidence for systematic reviews, health technology assessments and guidelines. STUDY DESIGN AND SETTING: This work was carried out by a project group within the GRADE Working Group, through brainstorming and iterative refinement of ideas, using input from workshops, presentations, and discussions at GRADE Working Group meetings to produce this document, which constitutes official GRADE guidance...
May 18, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28524381/antifungal-activity-of-gallic-acid-in-vitro-and-in-vivo
#15
Zhi-Jian Li, Meng Liu, Gulina Dawuti, Qin Dou, Yu Ma, Heng-Ge Liu, Silafu Aibai
Gallic acid (GA) is a polyphenol natural compound found in many medicinal plant species, including pomegranate rind (Punica granatum L.), and has been shown to have antiinflammatory and antibacterial properties. Pomegranate rind is used to treat bacterial and fungal pathogens in Uyghur and other systems of traditional medicine, but, surprisingly, the effects of GA on antifungal activity have not yet been reported. In this study, we aimed to investigate the inhibitory effects of GA on fungal strains both in vitro and in vivo...
May 19, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28490120/evaluation-of-antioxidant-potential-of-artocarpus-heterophyllus-l-j33-variety-fruit-waste-from-different-extraction-methods-and-identification-of-phenolic-constituents-by-lcms
#16
Mohd Nazrul Hisham Daud, Dian Nashiela Fatanah, Noriham Abdullah, Rohaya Ahmad
Artocarpus heterophyllus J33 (AhJ33) fruit is a popular and valuable jackfruit variety in Malaysia. For export, the pulp has to be separated from the skin which is usually discarded. Hence, the conversion of the fruit waste to food products with economic value needs to be explored utilizing the waste to wealth concept. This paper reports the evaluation of antioxidant potential of AhJ33 fruit waste (rind and rachis) extracts from three different extraction methods (maceration, percolation and Soxhlet). The antioxidant potential was assessed by DPPH radical scavenging, FRAP and β-carotene bleaching assays...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28487537/evidence-of-cross-cutting-and-redox-reaction-in-khatyrka-meteorite-reveals-metallic-al-minerals-formed-in-outer-space
#17
Chaney Lin, Lincoln S Hollister, Glenn J MacPherson, Luca Bindi, Chi Ma, Christopher L Andronicos, Paul J Steinhardt
We report on a fragment of the quasicrystal-bearing CV3 carbonaceous chondrite Khatyrka recovered from fine-grained, clay-rich sediments in the Koryak Mountains, Chukotka (Russia). We show higher melting-point silicate glass cross-cutting lower melting-point Al-Cu-Fe alloys, as well as unambiguous evidence of a reduction-oxidation reaction history between Al-Cu-Fe alloys and silicate melt. The redox reactions involve reduction of FeO and SiO2 to Fe and Fe-Si metal, and oxidation of metallic Al to Al2O3, occurring where silicate melt was in contact with Al-Cu-Fe alloys...
May 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28486520/rapid-expansion-of-the-invasive-oyster-crassostrea-gigas-at-its-northern-distribution-limit-in-europe-naturally-dispersed-or-introduced
#18
Marc B Anglès d'Auriac, Eli Rinde, Pia Norling, Sylvie Lapègue, André Staalstrøm, Dag Ø Hjermann, Jens Thaulow
The Pacific oyster, Crassostrea gigas, was introduced to Europe for aquaculture purposes, and has had a rapid and unforeseen northward expansion in northern Europe. The recent dramatic increase in number of C. gigas populations along the species' northern distribution limit has questioned the efficiency of Skagerrak as a dispersal barrier for transport and survival of larvae. We investigated the genetic connectivity and possible spreading patterns between Pacific oyster populations on the southern Norwegian coast (4 localities) and Swedish and Danish populations by means of DNA microsatellite analysis of adult oysters, and by simulating larvae drift...
2017: PloS One
https://www.readbyqxmd.com/read/28474137/clinical-features-and-predictive-value-of-serum-inflammatory-markers-of-perivascular-involvement-in-immunoglobulin-g4-related-disease
#19
Hideya Yamamoto, Eiji Sugiyama, Masahiro Serikawa, Fuminari Tatsugami, Michiya Yokozaki, Toshiro Kitagawa, Atsushi Senoo, Yumiko Kubo Nakamoto, Kazuo Awai, Kazuaki Chayama, Yasuki Kihara
Vascular and/or perivascular involvements of sclerotic inflammation (perivasculitis) are a complication of immunoglobulin G4-related disease (IgG4-RD). We sought to examine clinical manifestations of perivasculitis by computed tomography (CT) in patients with elevated serum IgG4 levels, and then to evaluate some potential predictors of perivasculitis in definite IgG4-RD patients. From a database of patients with serum IgG4 measurements, we selected 81 patients with elevated serum IgG4 levels (≥135 mg/dl)...
May 4, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28469705/suppression-of-cinnamoyl-coa-reductase-increases-the-level-of-monolignol-ferulates-incorporated-into-maize-lignins
#20
Rebecca A Smith, Cynthia L Cass, Mona Mazaheri, Rajandeep S Sekhon, Marlies Heckwolf, Heidi Kaeppler, Natalia de Leon, Shawn D Mansfield, Shawn M Kaeppler, John C Sedbrook, Steven D Karlen, John Ralph
BACKGROUND: The cell wall polymer lignin provides structural support and rigidity to plant cell walls, and therefore to the plant body. However, the recalcitrance associated with lignin impedes the extraction of polysaccharides from the cell wall to make plant-based biofuels and biomaterials. The cell wall digestibility can be improved by introducing labile ester bonds into the lignin backbone that can be easily broken under mild base treatment at room temperature. The FERULOYL-CoA MONOLIGNOL TRANSFERASE (FMT) enzyme, which may be naturally found in many plants, uses feruloyl-CoA and monolignols to synthesize the ester-linked monolignol ferulate conjugates...
2017: Biotechnology for Biofuels
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