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https://www.readbyqxmd.com/read/28047707/su-g-201-14-is-maximum-skin-dose-a-reliable-metric-for-accelerated-partial-breast-irradiation-with-brachytherapy
#1
S Park, O Ragab, S Patel, Y Kim, J Demanes, M Kamrava
PURPOSE: To evaluate the reliability of the maximum point dose (Dmax) to the skin surface as a dosimetric constraint, we investigated the correlation between Dmax at the skin surface and dose metrics at various definitions of skin thickness. METHODS: 42 patients treated with APBI using a Strut Adjusted Volume Implant (SAVI) applicator between 2010 and 2014 were retrospectively reviewed. Target (PTV_EVAL) and organs at risk (OARs: skin, lung, and ribs) were delineated on a CT following NSABP B-39 guidelines...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043333/a-nematicidal-tannin-from-punica-granatum-l-rind-and-its-physiological-effect-on-pine-wood-nematode-bursaphelenchus-xylophilus
#2
Qunqun Guo, Guicai Du, Hongtao Qi, Yanan Zhang, Tongqing Yue, Jingchao Wang, Ronggui Li
The ethanol extract of Punica granatum L. rind was tested to show significant nematicidal activity against pine wood nematode. Three nematicidal compounds were obtained from the ethanol extract by bioassay-guided fractionation and identified as punicalagin 1, punicalin 2, and corilagin 3 by mass and nuclear magnetic resonance spectral data analysis. Punicalagin 1 was most active against PWN among the purified compounds with the LC50 value of 307.08μM in 72h. According to the enzyme assays in vitro, punicalagin 1 could inhibit the activity of acetylcholinesterase, amylase and cellulase from PWN with IC50 value of 0...
January 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28031235/htp-nutraceutical-screening-for-histone-deacetylase-inhibitors-and-effects-of-hdacis-on-tumor-suppressing-mirnas-by-trichostatin-a-and-grapeseed-vitis-vinifera-in-hela-cells
#3
Elizabeth A Mazzio, Karam F A Soliman
BACKGROUND/AIM: Aggressive tumor malignancies are a consequence of delayed diagnosis, epigenetic/phenotype changes and chemo-radiation resistance. Histone deacetylases (HDACs) are a major epigenetic regulator of transcriptional repression, which are highly overexpressed in advanced malignancy. While original chemotherapy drugs were modeled after phytochemicals elucidated by botanical screenings, HDAC inhibitors (HDACi) such as apicidin, trichostatin A (TSA) and butyrate were discovered as products of fungus and microbes, in particular, gut microbiota...
January 2017: Cancer Genomics & Proteomics
https://www.readbyqxmd.com/read/28028308/metastatic-squamous-cell-carcinoma-of-the-pleura-a-rare-complication-of-hidradenitis-suppurativa
#4
Kiran Joglekar, Christopher Jackson, Dipen Kadaria, Amik Sodhi
BACKGROUND Squamous cell carcinoma (SCC), also known as Marjolin ulcer, is a rare complication of hidradenitis suppurativa (HS). Metastatic SCC from HS typically involves the axial skeleton or abdominopelvic viscera. Metastatic disease to the lungs is a rare phenomenon with only three reported cases of lung parenchyma. We present a biopsy proven case of metastatic SCC to the pleura from gluteal HS. CASE REPORT A 46-year-old male with a history of recently diagnosed Marjolin ulcer secondary to gluteal HS was transferred to our intensive care unit for acute hypoxemic respiratory failure secondary to recurrent pleural effusion...
December 28, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27991775/a-new-approach-to-sampling-intact-fe-plaque-reveals-si-induced-changes-in-fe-mineral-composition-and-shoot-as-in-rice
#5
Douglas C Amaral, Guilherme Lopes, Luiz R G Guilherme, Angelia L Seyfferth
The Fe (oxyhydr)oxide rind, or Fe plaque, that forms on aquatic plant roots is an important sorbent of metal(loid)s and plays a role in the attenuation of metal(loid) uptake into higher plants. However, the mineral composition of Fe plaque and thus its potential to sorb metal(loid)s is affected by solution chemistry. The predominant strategy to characterize Fe plaque using dithionite-citrate-bicarbonate (DCB) extraction and elemental analysis reveals total Fe quantity but misses the mineral structure of the Fe (oxyhydr)oxide...
January 3, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/27943588/separation-of-phenolic-acids-from-sugarcane-rind-by-online-solid-phase-extraction-with-high-speed-counter-current-chromatography
#6
Ping Geng, Yingtong Fang, Ronglong Xie, Weilun Hu, Xingjun Xi, Qiao Chu, Genlai Dong, Nusrat Shaheen, Yun Wei
Sugarcane rind contains some functional phenolic acids. The separation of these compounds from sugarcane rind is able to realize the integrated utilization of the crop and reduce environment pollution. In this paper, a novel protocol based on interfacing online solid-phase extraction with high-speed counter-current chromatography (HSCCC) was established, aiming at improving and simplifying the process of phenolic acids separation from sugarcane rind. The conditions of online solid-phase extraction with HSCCC involving solvent system, flow rate of mobile phase as well as saturated extent of absorption of solid-phase extraction were optimized to improve extraction efficiency and reduce separation time...
December 12, 2016: Journal of Separation Science
https://www.readbyqxmd.com/read/27889144/exploring-the-microbiota-of-the-red-brown-defect-in-smear-ripened-cheese-by-454-pyrosequencing-and-its-prevention-using-different-cleaning-systems
#7
Raffaele Guzzon, Ilaria Carafa, Kieran Tuohy, Gonzalo Cervantes, Luca Vernetti, Andrea Barmaz, Roberto Larcher, Elena Franciosi
Red-brown pigmentation can occasionally form in smeared-ripened cheese such as Fontina during the ripening process. This reaction is due to over-development of the typical microbiota present on the rind. Previous studies have demonstrated the relationship between red-brown pigmentation and the traditional utilization of wooden shelves during cheese ripening. The first part of the paper focuses on the characterisation of yeast and bacterial microbiota: plate counts and 454-pyrosequencing were performed in spoiled (n = 6) and non-spoiled cheeses (n = 6) and on the wooden shelves used during ripening...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27886374/effect-of-different-aloe-fractions-on-the-growth-of-lactic-acid-bacteria
#8
Giulia Chiodelli, Marco Pellizzoni, Gabriela Ruzickova, Luigi Lucini
Several foods on the market, such as yogurt and fermented milk, include mixtures of prebiotics and probiotic microorganisms effective in promoting the proliferation and equilibrium of intestinal bacteria, thus improving gut health. Particularly, researchers and the public have shown increasing interest in the combination of probiotics with natural substances that promote health or that can act as substrates to promote bacterial growth. The aim of this study is to evaluate the effects of different extracts of Aloe barbadensis and Aloe arborescens in fermented milk, taking into account both the prebiotic effect of aloe polysaccharides and the antimicrobial activity of several secondary metabolites...
January 2017: Journal of Food Science
https://www.readbyqxmd.com/read/27867111/anti-inflammatory-activity-of-punica-granatum-l-pomegranate-rind-extracts-applied-topically-to-ex-vivo-skin
#9
David M J Houston, Joachim Bugert, Stephen P Denyer, Charles M Heard
Coadministered pomegranate rind extract (PRE) and zinc (II) produces a potent virucidal activity against Herpes simplex virus (HSV); however, HSV infections are also associated with localised inflammation and pain. Here, the objective was to determine the anti-inflammatory activity and relative depth penetration of PRE, total pomegranate tannins (TPT) and zinc (II) in skin, ex vivo. PRE, TPT and ZnSO4 were dosed onto freshly excised ex vivo porcine skin mounted in Franz diffusion cells and analysed for COX-2, as a marker for modulation of the arachidonic acid inflammation pathway, by Western blotting and immunohistochemistry...
November 17, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27846826/natural-product-htp-screening-for-antibacterial-e-coli-0157-h7-and-anti-inflammatory-agents-in-lps-from-e-coli-o111-b4-activated-macrophages-and-microglial-cells-focus-on-sepsis
#10
Elizabeth A Mazzio, Nan Li, David Bauer, Patricia Mendonca, Equar Taka, Mohammed Darb, Leeshawn Thomas, Henry Williams, Karam F A Soliman
BACKGROUND: Acute systemic inflammatory response syndrome arising from infection can lead to multiple organ failure and death, with greater susceptibility occurring in immunocompromised individuals. Moreover, sub-acute chronic inflammation is a contributor to the pathology of diverse degenerative diseases (Parkinson's disease, Alzheimer's disease and arthritis). Given the known limitations in Western medicine to treat a broad range of inflammatory related illness as well as the emergence of antibiotic resistance, there is a renewed interest in complementary and alternative medicines (CAMs) to achieve these means...
November 15, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27821402/ischemic-stroke-and-risk-of-venous-thromboembolism-in-the-general-population-the-troms%C3%A3-study
#11
Ludvig B Rinde, Birgit Småbrekke, Ellisiv B Mathiesen, Maja-Lisa Løchen, Inger Njølstad, Erin M Hald, Tom Wilsgaard, Sigrid K Brækkan, John-Bjarne Hansen
BACKGROUND: Even though clinical data support a relation between ischemic stroke and venous thromboembolism (VTE), the strength and time dependence of the association remain to be settled at the population level. We therefore aimed to investigate the association between ischemic stroke and VTE in a prospective population-based cohort. METHODS AND RESULTS: Participants (n=30 002) were recruited from 3 surveys of the Tromsø study (conducted in 1994-1995, 2001, and 2007-2008) and followed through 2010...
November 7, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27815644/hebephilia-and-other-chronophilic-puzzles
#12
Bruce Rind
No abstract text is available yet for this article.
November 4, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27800440/evolution-of-the-microbiological-profile-of-vacuum-packed-ricotta-salata-cheese-during-shelf-life
#13
Daniele Casti, Christian Scarano, Carlo Pala, Francesca Cossu, Sonia Lamon, Vincenzo Spanu, Michela Ibba, Anna Maria Mocci, Francesco Tedde, Gavino Nieddu, Carlo Spanu, Enrico Pietro Luigi De Santis
Ricotta salata cheese is a salted variety of ricotta traditionally made in Sardinia (Italy) from the whey remaining after the production of Pecorino Romano protected designation of origin or other sheep milk cheeses. Ricotta salata cheese is very critical for the possible growth of pathogenic and spoilage microorganisms. Sporadic cases of listeriosis associated with ricotta salata cheese have been reported over recent years. The objective of the present study was to assess the evolution of spoilage and pathogen microorganism of vacuum-packed ricotta salata cheese during the entire product shelf-life...
April 19, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/27795388/biotic-interactions-shape-the-ecological-distributions-of-staphylococcus-species
#14
Erik K Kastman, Noelani Kamelamela, Josh W Norville, Casey M Cosetta, Rachel J Dutton, Benjamin E Wolfe
: Many metagenomic sequencing studies have observed the presence of closely related bacterial species or genotypes in the same microbiome. Previous attempts to explain these patterns of microdiversity have focused on the abiotic environment, but few have considered how biotic interactions could drive patterns of microbiome diversity. We dissected the patterns, processes, and mechanisms shaping the ecological distributions of three closely related Staphylococcus species in cheese rind biofilms...
October 18, 2016: MBio
https://www.readbyqxmd.com/read/27785381/chloroplast-sequence-of-treegourd-crescentia-cujete-bignoniaceae-to-study-phylogeography-and-domestication
#15
Priscila Ambrósio Moreira, Cédric Mariac, Nora Scarcelli, Marie Couderc, Doriane Picanço Rodrigues, Charles R Clement, Yves Vigouroux
PREMISE OF THE STUDY: Crescentia cujete (Bignoniaceae) fruit rinds are traditionally used for storage vessels and handicrafts. We assembled its chloroplast genome and identified single-nucleotide polymorphisms (SNPs). METHODS AND RESULTS: Using a genome skimming approach, the whole chloroplast of C. cujete was assembled using 3,106,928 sequence reads of 150 bp. The chloroplast is 154,662 bp in length, structurally divided into a large single copy region (84,788 bp), a small single copy region (18,299 bp), and two inverted repeat regions (51,575 bp) with 88 genes annotated...
October 2016: Applications in Plant Sciences
https://www.readbyqxmd.com/read/27783171/reactions-to-first-postpubertal-female-same-sex-sexual-experience-in-the-kinsey-sample-a-comparison-of-minors-with-peers-minors-with-adults-and-adults-with-adults
#16
Bruce Rind
This study examined reactions to first postpubertal same-sex sexual experience in the Kinsey female same-sex sample (consisting of females with extensive postpubertal same-sex experience) as a function of participant and partner ages. As such, it complemented the Rind and Welter (2016) study, which examined the same in the Kinsey male same-sex sample. Data were collected by Kinsey interviewers between 1939 and 1961 (M year = 1947). Girls under 18 (M age = 14.9), whose sexual experience was with a woman (M age = 26...
October 25, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27774991/two-identified-looming-detectors-in-the-locust-ubiquitous-lateral-connections-among-their-inputs-contribute-to-selective-responses-to-looming-objects
#17
F Claire Rind, Stefan Wernitznig, Peter Pölt, Armin Zankel, Daniel Gütl, Julieta Sztarker, Gerd Leitinger
In locusts, two lobula giant movement detector neurons (LGMDs) act as looming object detectors. Their reproducible responses to looming and their ethological significance makes them models for single neuron computation. But there is no comprehensive picture of the neurons that connect directly to each LGMD. We used high-through-put serial block-face scanning-electron-microscopy to reconstruct the network of input-synapses onto the LGMDs over spatial scales ranging from single synapses and small circuits, up to dendritic branches and total excitatory input...
October 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27710867/highlighting-the-microbial-diversity-of-12-french-cheese-varieties
#18
Eric Dugat-Bony, Lucille Garnier, Jeremie Denonfoux, Stéphanie Ferreira, Anne-Sophie Sarthou, Pascal Bonnarme, Françoise Irlinger
Surface-ripened cheeses host complex microbial communities responsible for the transformation of milk into cheese as well as the development of important properties in terms of texture, color and sensory perception. In this study, we used high-throughput amplicon sequencing to decipher the bacterial and fungal diversity of 60 cheeses belonging to 12 popular French cheese varieties. Using this approach, 76 bacterial and 44 fungal phylotypes were identified. Major differences were observed between rind and core samples and also according to cheese varieties and manufacturing processes...
December 5, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27702395/identification-and-quantification-of-adulteration-in-garcinia-cambogia-commercial-products-by-chromatographic-and-spectrometric-methods
#19
Nargis Jamila, Ji Yeon Choi, Joon Ho Hong, Eun Yeong Nho, Naeem Khan, Cheon Ho Jo, Hyang Sook Chun, Kyong Su Kim
Species of genus Garcinia are rich sources of bioactive constituents with antimicrobial, anticancer, anti-inflammatory, hepatoprotective and anti-HIV activities. Commercial products of Garcinia cambogia are used as anti-obesity drugs with increasing market demand. Because of the high price of its products, it can be adulterated with similar lower-priced species. This study was designed to develop and validate an accurate and efficient method for the detection of any adulteration (G. indica) in G. cambogia products...
December 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/27699399/should-we-screen-for-type-2-diabetes-grand-rounds-discussion-from-beth-israel-deaconess-medical-center
#20
Gerald W Smetana, Martin J Abrahamson, David M Rind
The prevalence of diabetes in the United States is rising. Twelve percent of U.S. adults have diabetes and another 37% have impaired fasting glucose or impaired glucose tolerance. Diabetes is a major risk factor for such outcomes as cardiovascular disease, blindness, chronic kidney disease, and limb amputation. An important consideration is whether screening for abnormal glucose levels or diabetes reduces cardiovascular or all-cause morbidity and mortality. In October 2015, the U.S. Preventive Services Task Force published recommendations on screening for abnormal blood glucose and concluded that intensive lifestyle interventions have a moderate benefit in reducing progression to diabetes in patients who have abnormal blood glucose levels detected by screening...
October 4, 2016: Annals of Internal Medicine
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