keyword
https://read.qxmd.com/read/38523726/breast-metastasis-an-unusual-cause-of-malignant-breast-lesion
#1
JOURNAL ARTICLE
Dunkan Petersbourg
Teaching point: Although rare, an intra-mammary metastasis from extramammary cancer should be considered in a patient with an oncological history.
2024: Journal of the Belgian Society of Radiology
https://read.qxmd.com/read/38491916/effect-of-iodized-oil-embolization-on-temperature-change-during-cryoablation-for-renal-cell-carcinoma
#2
JOURNAL ARTICLE
Nai-Wen Chang, Chien-An Liu, Jia-An Hong, Shu-Huei Shen
INTRODUCTION: We aimed to evaluate the effect of transcatheter arterial embolization (TAE) with iodized oil (Lipiodol) on temperature change during cryoablation (CA) for renal cell carcinoma (RCC). MATERIAL AND METHODS: We retrospectively reviewed patients receiving CA for RCC from February 2020 to July 2021, including those who received Lipiodol TAE prior to CA (TAE group) and those who underwent only CA with comparable clinical and tumor characteristics (non-TAE group)...
March 16, 2024: Minimally Invasive Therapy & Allied Technologies: MITAT
https://read.qxmd.com/read/38485610/exploring-the-adam12-expression-in-clear-cell-renal-cell-carcinoma-a-radiogenomic-analysis-on-ct-imaging
#3
JOURNAL ARTICLE
Federico Greco, Andrea Panunzio, Caterina Bernetti, Alessandro Tafuri, Bruno Beomonte Zobel, Carlo Augusto Mallio
RATIONALE AND OBJECTIVES: Radiogenomics of clear cell renal cell carcinoma (ccRCC) has been developed thanks to the availability of genomic data, both gene expressions and gene mutations, obtained through the sequencing of ccRCC genome. These data are collected in the Cancer Genome Atlas (TCGA) Research Network-work. Disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) gene belongs to the family of genes coding for multidomain and multifunctional type I transmembrane proteins ADAMs...
March 13, 2024: Academic Radiology
https://read.qxmd.com/read/38483602/percutaneous-image-guided-cryoablation-of-endophytic-renal-cell-carcinoma
#4
JOURNAL ARTICLE
Christian Greve Jensen, Marco Dybdahl, John Valtersson, Bo Redder Mussmann, Louise Aarup Duus, Theresa Junker, Pia Iben Pietersen, Lars Lund, Brian T Welch, Ole Graumann
PURPOSE: Endophytic renal cancer treatment is a challenge. Due to difficulties in endophytic tumor visualization during surgical extirpation, image-guided percutaneous cryoablation (PCA) is an attractive alternative. The minimally invasive nature of PCA makes it favorable for comorbid patients as well as patients in which surgery is contraindicated. Oncological outcomes and complications after PCA of endophytic biopsy-proven renal cell carcinoma (RCC) were reviewed in this study. MATERIALS AND METHODS: Patients were included after a multidisciplinary team conference from January 2015 to November 2021...
March 14, 2024: Cardiovascular and Interventional Radiology
https://read.qxmd.com/read/38480074/computed-tomography-based-radiomics-to-predict-foxm1-expression-and-overall-survival-in-patients-with-clear-cell-renal-cell-carcinoma
#5
JOURNAL ARTICLE
Jingwei Zhao, Qi Zhang, Yan Chen, Xinming Zhao
RATIONALE AND OBJECTIVES: To establish a computed tomography (CT)-based radiomics model to predict Fork head box M1(FOXM1) expression levels and develop a combined model for prognostic prediction in patients with clear cell renal cell carcinoma (ccRCC). MATERIALS AND METHODS: A total of 529 patients were utilized to assess the prognostic significance of FOXM1 expression and were subsequently categorized into low and high FOXM1 expression groups. 184 patients with CT images were randomly divided into training and validation cohorts...
March 12, 2024: Academic Radiology
https://read.qxmd.com/read/38478923/efficacy-safety-and-tolerability-of-tivozanib-in-heavily-pretreated-patients-with-advanced-clear-cell-renal-cell-carcinoma
#6
JOURNAL ARTICLE
Andrew C Johns, Matthew T Campbell, Mamie Gao, Andrew W Hahn, Zita Lim, Emily Wang, Jianjun Gao, Amishi Y Shah, Pavlos Msaouel, Nizar M Tannir
BACKGROUND: Tivozanib has been approved as a third-line or later therapy for advanced renal cell carcinoma based on the TIVO-3 trial, which was conducted before immune checkpoint therapies (ICT), cabozantinib, and lenvatinib/everolimus became incorporated in the current sequential treatment paradigm for advanced clear cell RCC (ccRCC). METHODS: We performed a retrospective study of patients with advanced ccRCC treated with tivozanib at MD Anderson Cancer Center during 6/2021-7/2023...
March 13, 2024: Oncologist
https://read.qxmd.com/read/38477383/percutaneous-microwave-ablation-of-t1a-renal-cell-carcinomas-a-10-year-single-center-retrospective-review
#7
JOURNAL ARTICLE
Cassie McCloskey, Angela Jacques, Dylan McCloskey, Jonathan Tibballs
INTRODUCTION: Partial nephrectomy is currently the preferred treatment option for T1a renal cell carcinomas (RCC), with nephron-sparing techniques, including microwave ablation, becoming more common in select patients. Primary aims are to document outcomes of microwave ablation for T1a RCCs in an Australian tertiary centre to add to the evidence for its safety and efficacy. METHODS: The prospectively maintained Sir Charles Gairdner Hospital Interventional Radiology database was retrospectively searched for all Renal Microwave ablations completed between June 2012 and February 2022...
March 13, 2024: Journal of Medical Imaging and Radiation Oncology
https://read.qxmd.com/read/38475661/ctdna-predicts-clinical-t1a-to-pathological-t3a-upstaging-after-partial-nephrectomy
#8
JOURNAL ARTICLE
Jee Soo Park, Hongkyung Kim, Won Sik Jang, Jongchan Kim, Won Sik Ham, Seung-Tae Lee
Most patients diagnosed with clear cell renal cell carcinoma (ccRCC) are also detected with small and organ-confined tumors, and the majority of these are classified as clinical tumor stage 1a (cT1a). A considerable proportion of patients with cT1 RCC shows tumor upstaging to pathological stage 3a (pT3a), and these patients have worse oncological outcomes. The role of circulating tumor DNA (ctDNA) in RCC has been limited to monitoring treatment response and resistance. Therefore, the present study aimed to evaluate the potential of ctDNA in predicting pT3a upstaging in cT1a ccRCC...
March 12, 2024: Cancer Science
https://read.qxmd.com/read/38467854/characterization-of-renal-masses-with-mri-based-radiomics-assessment-of-inter-package-and-inter-observer-reproducibility-in-a-prospective-pilot-study
#9
JOURNAL ARTICLE
Haitham Al-Mubarak, Octavia Bane, Nicolas Gillingham, Christopher Kyriakakos, Ghadi Abboud, Jordan Cuevas, Janette Gonzalez, Kirolos Meilika, Amir Horowitz, Hsin-Hui Vivien Huang, Jorge Daza, Valentin Fauveau, Ketan Badani, Satish E Viswanath, Bachir Taouli, Sara Lewis
OBJECTIVES: To evaluate radiomics features' reproducibility using inter-package/inter-observer measurement analysis in renal masses (RMs) based on MRI and to employ machine learning (ML) models for RM characterization. METHODS: 32 Patients (23M/9F; age 61.8 ± 10.6 years) with RMs (25 renal cell carcinomas (RCC)/7 benign masses; mean size, 3.43 ± 1.73 cm) undergoing resection were prospectively recruited. All patients underwent 1...
March 12, 2024: Abdominal Radiology
https://read.qxmd.com/read/38460936/primary-angiosarcoma-of-the-kidney-a-challenging-diagnosis
#10
JOURNAL ARTICLE
Arthur Peyrottes, Sylvain Bodard, Marc-Olivier Timsit, Arnaud Mejean, Frederic Panthier, François Audenet
Angiosarcoma is a rare malignancy derived from endothelial cells which behaves aggressively. Primary angiosarcoma of the kidney is even rarer, and its clinical and radiological presentations do not differ from clear cells renal cell carcinoma (ccRCC). Management protocols are not standardized, although nephrectomy is usually performed. Subsequent treatments (chemotherapy, radiotherapy, and lately, targeted therapies) vary considerably. Herein, we report the case of a middle-aged patient harboring primary angiosarcoma of the left kidney and discuss its presentation and management in light of current guidelines...
March 7, 2024: Fr J Urol
https://read.qxmd.com/read/38456787/the-prevalence-and-radiologic-features-of-renal-cancers-associated-with-flcn-bap1-sdh-and-met-germline-mutations
#11
JOURNAL ARTICLE
Charlotte Charbel, Pamela I Causa Andrieu, Mohamed Soliman, Sungmin Woo, Junting Zheng, Marinela Capanu, Ines Nikolovski, Hebert A Vargas, Murad Abusamra, Maria I Carlo
Purpose To investigate the prevalence of FLCN, BAP1, SDH , and MET mutations in an oncologic cohort and determine the prevalence, clinical features, and imaging features of renal cell carcinoma (RCC) associated with these mutations. Secondarily, to determine the prevalence of encountered benign renal lesions. Materials and Methods From 25 220 patients with cancer who prospectively underwent germline analysis with a panel of more than 70 cancer-predisposing genes from 2015 to 2021, patients with FLCN, BAP1, SDH , or MET mutations were retrospectively identified...
March 2024: Radiology. Imaging cancer
https://read.qxmd.com/read/38416370/multilocular-cystic-nephroma-in-an-adult-a-diagnostic-quandary
#12
JOURNAL ARTICLE
Ritu Verma, Jyoti Verma, Neelima Gupta
Multilocular cystic nephroma (MLCN) is an unusual, benign slow-growing renal cystic neoplasm which mimics other cystic renal lesions and has such clinical, radiological, and morphological features that causes diagnostic dilemma. MLCN lies in the spectrum of mixed epithelial and stromal tumor (MEST) family of kidney. According to World Health Organization (WHO 2016 classification), MEST encompasses spectrum of tumors ranging from predominantly cystic tumors, adult cystic nephroma (ACN) to tumors that are variably solid (MEST), thus creating diagnostic dilemma...
February 28, 2024: CEN Case Reports
https://read.qxmd.com/read/38415576/contrast-enhanced-ultrasound-of-the-indeterminate-renal-mass-from-the-ajr-how-we-do-it-special-series
#13
REVIEW
Khaled Y Elbanna, Satheesh Krishna, Antonio Finelli, Mostafa Atri
Contrast-enhanced ultrasound (CEUS) is distinguished from CT and MRI by the use of microbubble ultrasound contrast agents (UCAs) with intravascular blood pool distribution. When performing CEUS, low-intensity ultrasound allows real-time tissue subtraction imaging, whereas high-intensity ultrasound leads to microbubble destruction, enabling visualization of the contrast inflow pattern. CEUS has exceptional contrast resolution that enables the detection of even minimal blood flow, achieving very high NPV for ruling out vascular perfusion and providing high frame rates in the evaluation of tissue perfusion dynamics...
February 28, 2024: AJR. American Journal of Roentgenology
https://read.qxmd.com/read/38411691/renal-cell-carcinoma-and-venous-tumor-thrombus-predicting-sarcomatoid-dedifferentiation-through-preoperative-ivim-based-mr-imaging
#14
JOURNAL ARTICLE
Jian Zhao, Xiaohui Ding, Shaopeng Zhou, Meifeng Wang, Cheng Peng, Xu Bai, Xiaojing Zhang, Kan Liu, Xin Ma, Xu Zhang, Haiyi Wang
PURPOSE: To evaluate the value of preoperative intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and conventional MRI indicators in identifying sarcomatoid dedifferentiation in renal cell carcinoma (RCC) and tumor thrombus. METHODS: From September 2016 to April 2023, consecutive patients with RCC and tumor thrombus who received routine MRI examination and IVIM-DWI before radical resection were enrolled prospectively. Kaplan-Meier method with log-rank test was used to calculate and compare the survival probability...
February 27, 2024: Abdominal Radiology
https://read.qxmd.com/read/38410103/time-to-strategy-failure-and-treatment-beyond-progression-in-pretreated-metastatic-renal-cell-carcinoma-patients-receiving-nivolumab-post-hoc-analysis-of-the-meet-uro-15-study
#15
JOURNAL ARTICLE
Veronica Murianni, Alessio Signori, Sebastiano Buti, Sara Elena Rebuzzi, Davide Bimbatti, Ugo De Giorgi, Silvia Chiellino, Luca Galli, Paolo Andrea Zucali, Cristina Masini, Emanuele Naglieri, Giuseppe Procopio, Michele Milella, Lucia Fratino, Cinzia Baldessari, Riccardo Ricotta, Veronica Mollica, Mariella Sorarù, Marianna Tudini, Veronica Prati, Andrea Malgeri, Francesco Atzori, Marilena Di Napoli, Orazio Caffo, Massimiliano Spada, Franco Morelli, Giuseppe Prati, Franco Nolè, Francesca Vignani, Alessia Cavo, Helga Lipari, Giandomenico Roviello, Fabio Catalano, Alessandra Damassi, Malvina Cremante, Pasquale Rescigno, Giuseppe Fornarini, Giuseppe Luigi Banna
BACKGROUND: Immunotherapies exhibit peculiar cancer response patterns in contrast to chemotherapy and targeted therapy. Some patients experience disease response after initial progression or durable responses after treatment interruption. In clinical practice, immune checkpoint inhibitors may be continued after radiological progression if clinical benefit is observed. As a result, estimating progression-free survival (PFS) based on the first disease progression may not accurately reflect the actual benefit of immunotherapy...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38407627/assessing-visibility-and-bone-changes-of-spinal-metastases-in-ct-scans-a-comprehensive-analysis-across-diverse-cancer-types
#16
JOURNAL ARTICLE
Jung Oh Lee, Dong Hyun Kim, Hee-Dong Chae, Eugene Lee, Ji Hee Kang, Ji Hyun Lee, Hyo Jin Kim, Jiwoon Seo, Jee Won Chai
OBJECTIVES: To analyze the characteristics of spinal metastasis in CT scans across diverse cancers for effective diagnosis and treatment, using MRI as the gold standard. METHODS: A retrospective study of 309 patients from four centers, who underwent concurrent CT and spinal MRI, revealing spinal metastasis, was conducted. Data on metastasis including total number, volume, visibility on CT (visible, indeterminate, or invisible), and type of bone change were collected...
February 26, 2024: Skeletal Radiology
https://read.qxmd.com/read/38388790/depiction-rate-of-feeding-arteries-of-renal-cell-carcinoma-on-four-dimensional-computed-tomography-angiography
#17
JOURNAL ARTICLE
Kazuaki Munetomo, Yusuke Matsui, Koji Tomita, Mayu Uka, Noriyuki Umakoshi, Takahiro Kawabata, Yusuke Morimitsu, Toshihiro Iguchi, Takao Hiraki
PURPOSE: To retrospectively evaluate the depiction rate of feeding arteries in biopsy-proven clear cell renal cell carcinoma (CCRCC) on four-dimensional computed tomography angiography (4D-CTA) images. MATERIALS AND METHODS: This study included 22 patients with 22 CCRCC and 30 feeding arteries treated with transcatheter renal artery embolization. The depiction rate of the feeding arteries on preprocedural 4D-CTA was evaluated. Images were acquired by 320-row multi-detector computed tomography (CT) 15‒36 s after starting to inject a contrast agent (600 mg/kg iodine) intravenously into patients at 2...
February 23, 2024: Japanese Journal of Radiology
https://read.qxmd.com/read/38387043/med15-tfe3-fusion-renal-cell-carcinoma-with-extensive-cystic-change-a-clinicopathologic-and-molecular-genetic-study-of-2-cases-with-an-emphasis-on-differential-diagnosis
#18
JOURNAL ARTICLE
Xiaona Yin, Xingen Hu, Jiayun Xu, Danting Xiong, Ming Zhao
OBJECTIVES: TFE3-rearranged renal cell carcinomas (RCCs) harbor gene fusions between TFE3 and 1 of many partner genes. MED15::TFE3 fusion RCC is rare, often cystic, and easily misdiagnosed. METHODS: This study aimed to characterize 2 cases of MED15::TFE3 fusion RCC with extensive cystic change using fluorescence in situ hybridization and targeted RNA sequencing. RESULTS: Both patients were young adult women aged 29 and 35 years. Radiologically, both presented with a cystic Bosniak category II renal lesion...
February 22, 2024: American Journal of Clinical Pathology
https://read.qxmd.com/read/38383255/ct-derived-radiomics-predict-the-growth-rate-of-renal-tumours-in-von-hippel-lindau-syndrome
#19
JOURNAL ARTICLE
S Singh, F Dehghani Firouzabadi, A Chaurasia, F Homayounieh, M W Ball, F Huda, E B Turkbey, W M Linehan, A A Malayeri
AIM: To predict renal tumour growth patterns in von Hippel-Lindau syndrome by utilising radiomic features to assist in developing personalised surveillance plans leading to better patient outcomes. MATERIALS AND METHODS: The study evaluated 78 renal tumours in 55 patients with histopathologically-confirmed clear cell renal cell carcinomas (ccRCCs), which were segmented and radiomics were extracted. Volumetric doubling time (VDT) classified the tumours into fast-growing (VDT <365 days) or slow-growing (VDT ≥365 days)...
February 8, 2024: Clinical Radiology
https://read.qxmd.com/read/38375738/institutional-clinical-indication-based-typical-dose-values-of-multiphasic-abdominopelvic-computed-tomography-examinations
#20
JOURNAL ARTICLE
Süleyman Filiz, Safiye Gürel, Kamil Gürel
PURPOSE: Our study aimed to obtain clinical indication-based typical dose values and size-specific dose estimates (SSDEs) for multiphasic abdominopelvic computed tomography (CT) examinations and to review our data with published diagnostic reference levels (DRLs). METHODS: In this retrospective study, multiphasic liver, kidney, pancreas, and mesenteric ischemia protocol CT scans performed at our center between January 2018 and December 2021 were analyzed. The clinical indications were hepatocellular carcinoma, renal cell carcinoma, pancreas adenocarcinoma, and mesenteric ischemia...
February 20, 2024: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
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