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renal cell carcinoma radiology

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https://www.readbyqxmd.com/read/28619630/hilar-fat-infiltration-a-new-prognostic-factor-in-metastatic-clear-cell-renal-cell-carcinoma-with-first-line-sunitinib-treatment
#1
Solène-Florence Kammerer-Jacquet, Angelique Brunot, Karim Bensalah, Boris Campillo-Gimenez, Mathilde Lefort, Sahar Bayat, Alain Ravaud, Frantz Dupuis, Mokrane Yacoub, Gregory Verhoest, Benoit Peyronnet, Romain Mathieu, Alexandra Lespagnol, Jean Mosser, Julien Edeline, Brigitte Laguerre, Jean-Christophe Bernhard, Nathalie Rioux-Leclercq
INTRODUCTION: The selection of patients with metastatic clear cell renal cell carcinoma (ccRCC) who may benefit from targeted tyrosine kinase inhibitors has been a challenge, even more so now with the advent of new therapies. Hilar fat infiltration (HFI) is a validated prognostic factor in nonmetastatic ccRCC (TNM 2009 staging system) but has never been studied in metastatic patients. We aimed to assess its phenotype and prognostic effect in patients with metastatic ccRCC treated with first-line sunitinib...
June 12, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28596926/invasive-mucormycosis-induced-pneumopericardium-a-rare-cause-of-pneumopericardium-in-an-immunocompromised-patient
#2
Sana Khan, Muhammad Waqar Elahi, Waqas Ullah, Hafez Mohammad Ammar Abdullah, Ejaz Ahmad, Mayar Al Mohajer, Aneela Majeed
Mucor and Rhizopus cause life-threatening infections primarily involving the lungs and sinuses, which disseminate very rapidly by necrosis and infarction of the contiguous tissues. We present a case of a 64-year-old African American posttransplant patient who presented with a productive cough and weight loss. He had a past surgical history of renal transplant for renal cell carcinoma and was on dual immunosuppressive therapy, that is, mycophenolate and tacrolimus. During his hospital stay, he developed a pneumopericardium due to the direct extension of a lung lesion...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28596583/dynamic-contrast-enhanced-mri-in-renal-tumors-common-subtype-differentiation-using-pharmacokinetics
#3
Hai-Yi Wang, Zi-Hua Su, Xiao Xu, Ning Huang, Zhi-Peng Sun, Ying-Wei Wang, Lu Li, Ai-Tao Guo, Xin Chen, Xin Ma, Lin Ma, Hui-Yi Ye
Preoperative renal tumor subtype differentiation is important for radiology and urology in clinical practice. Pharmacokinetic data (K (trans) & V e, etc.) derived from dynamic contrast-enhanced MRI (DCE-MRI) have been used to investigate tumor vessel permeability. In this prospective study on DCE-MRI pharmacokinetic studies, we enrolled patients with five common renal tumor subtypes: clear cell renal cell carcinoma (ccRCC; n = 65), papillary renal cell carcinoma (pRCC; n = 12), chromophobic renal cell carcinoma (cRCC; n = 9), uroepithelial carcinoma (UEC; n = 14), and fat-poor angiomyolipoma (fpAML; n = 10)...
June 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28593146/cholesterol-granuloma-of-the-abdominal-wall-an-unusual-finding-in-the-setting-of-renal-cell-carcinoma
#4
Robert Abraham Obeid, Daniel James Hoppe, Tamer Jacob Dafashy, Rebecca Elaine Waters, Susan Elizabeth Tarry
Cholesterol granulomas are composed of a distinct type of granulation tissue that contains lipids and cholesterol crystals. They are not believed to be a pathological entity, but rather an inflammatory tissue reaction to the presence of trapped blood secondary to localized hemorrhage.(1) Cholesterol granulomas can be identified histologically by the presence of multi-nucleated giant cells, hemosiderin, and red blood cells along with their associated break-down products.(1) Recognizing cholesterol granulomas can provide clinical utility as they demonstrate a tendency to mimic carcinoma both clinically and radiologically...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28592028/-analysis-of-12-cases-of-exogenous-lipoid-pneumonia-confirmed-by-pathology
#5
Y X Wang, F Fang, Y F Guo, Y M Li, T Y Sun, M Zhang, J Chen, B M Fang
Objective: To study the etiological, clinical, radiological, diagnostic, therapeutic, and prognostic manifestations of exogenous lipoid pneumonia (ELP), and therefore to improve the diagnosis and treatment of this disease. Methods: The clinical data of 12 cases of ELP confirmed by pathology were retrospectively analyzed. Results: The patients consisted of 9 males and 3 females, with an average age of 73.8 years (range, 44 to 100 years). The underlying diseases were variable, including diseases affecting the general condition (multiple organ failure, chronic heart and renal insufficiency, pemphigoid, etc) and conditions with increased risk of aspiration (sequelae of cerebrovascular disease, Alzheimer's disease, advanced stage of nasopharyngeal carcinoma, paralytic ileus, etc)...
June 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28572534/contrast-media-enhancement-reduction-predicts-tumor-response-to-presurgical-molecular-targeting-therapy-in-patients-with-advanced-renal-cell-carcinoma
#6
Shogo Hosogoe, Shingo Hatakeyama, Ayumu Kusaka, Itsuto Hamano, Yoshimi Tanaka, Kazuhisa Hagiwara, Hideaki Hirai, Satoko Morohashi, Hiroshi Kijima, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Chikara Ohyama
BACKGROUND AND OBJECTIVE: A quantitative tumor response evaluation to molecular-targeting agents in advanced renal cell carcinoma (RCC) is debatable. We aimed to evaluate the relationship between radiologic tumor response and pathological response in patients with advanced RCC who underwent presurgical therapy. RESULTS: Of 34 patients, 31 underwent scheduled radical nephrectomy. Presurgical therapy agents included axitinib (n = 26), everolimus (n = 3), sunitinib (n = 1), and axitinib followed by temsirolimus (n = 1)...
May 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28571151/leiomyosarcoma-of-renal-vein-a-rare-case-report
#7
Sandeep Ojha, Ramarao Nilkanthe, Jyoti Valecha, Farah Meenai, Amit Haritwal
Leiomyosarcomas (LMS) arising from vascular channel are rare and more often arise from inferior vena cava and pulmonary arteries. Primary renal vein LMS are even rarer and occur predominantly in females with peak in fifth and sixth decade. Preoperative diagnosis is difficult because these are rare tumours and present with symptoms and radiological findings similar to Renal Cell Carcinoma (RCC). We report a case of 55-year-old female who presented with abdominal discomfort with radiology showing a renal mass with features of RCC, radical nephrectomy was done and resected tumour showed an attachment to the wall of renal vein with morphology resembling LMS...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28567328/squamous-cell-carcinoma-of-the-renal-pelvis-atypical-presentation-of-a-rare-malignancy
#8
Kyrollis Attalla, Kenneth Haines, Daniel Labow, Reza Mehrazin
Primary squamous cell carcinoma (SCC) of the renal pelvis is exceedingly rare and is associated with advanced stage at diagnosis and a poor prognosis. Diagnosis is often difficult due to vague presenting symptoms and nonspecific radiologic findings. The mainstay of treatment is nephrectomy, with cisplatin based chemotherapy and palliative radiation reserved for metastatic disease. We report a SCC of the renal pelvis in a 72 year-old female who presented with abdominal pain. To date, this is the largest SCC originating from the renal pelvis reported in the literature, made even more exceptional by the lack of antecedent risk factors...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28533051/features-of-ipsilateral-renal-recurrences-after-partial-nephrectomy-a-proposal-of-a-pathogenetic-classification
#9
Alessandro Antonelli, Maria Furlan, Regina Tardanico, Simona Fisogni, Mario Sodano, Francesca Carobbio, Sandra Belotti, Alberto Cozzoli, Tiziano Zanotelli, Claudio Simeone
BACKGROUND: Poor data are reported on the pathogenesis of ipsilateral relapse (IR) after partial nephrectomy (PN). The objective of this study was to investigate features of IR after PN with the intention to propose a pathogenetic classification. MATERIALS AND METHODS: Retrospective consultation of an institutional database that stores the data of 683 patients submitted to PN since 1993. The clinical, radiological, and follow-up data of the cases submitted to salvage nephrectomy due to an IR were analyzed...
April 26, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28529741/pazopanib-induced-asymptomatic-radiological-acute-pancreatitis-a-case-report
#10
Iosune Baraibar, Almudena Quílez, Diego Salas, Marta Román, Christian Rolfo, José L Pérez-Gracia, Ignacio Gil-Bazo
The universal clinical use of multi-targeted tyrosine kinase inhibitors (TKIs) in patients diagnosed with advanced renal cell carcinoma (RCC) has significantly prolonged their estimated survival times and their quality of life. However, several adverse side-effects associated predominantly with the inhibition of the vascular endothelial growth factor receptor by these drugs may prove to be potentially life-threatening. One adverse event that is only rarely observed with the use of TKIs in this clinical setting is acute pancreatitis...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28511950/benign-m%C3%A3-llerian-inclusions-in-lymphadenectomies-for-renal-cell-carcinoma-a-radiologic-and-pathologic-mimic-of-metastases
#11
Christopher P Dall, David S Sharp, Debra L Zynger
No abstract text is available yet for this article.
April 26, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28470395/irreversible-electroporation-to-treat-malignant-tumor-recurrences-within-the-pelvic-cavity-a-case-series
#12
L G P H Vroomen, H J Scheffer, M C A M Melenhorst, N van Grieken, M P van den Tol, M R Meijerink
OBJECTIVE: To describe the initial experience with irreversible electroporation (IRE) to treat pelvic tumor recurrences. METHODS: A retrospective single-center analysis was performed. Adverse events were recorded using Common Terminology Criteria of Adverse Events (CTCAE) 4.0. Clinical outcome was determined using pain- and general- symptom assessment, including Seddon's peripheral nerve injury (PNI) types. Radiological outcome was evaluated by comparing baseline with three-month 18F-FDG PET-CT follow-up...
May 3, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28462166/papillary-renal-cell-carcinoma-revealed-by-renal-traumatism-a-case-report-in-lom%C3%A3
#13
Tchilabalo Matchonna Kpatcha, Kodjo Tengué, Gnimdou Botcho, Tchin Darré, Kossi Akomola Sabi, Komi Hola Sikpa, Essomendedou Léloua, Edoé Viyomé Séwa, Obube Amegayibor, Tsipa Anoukoum, Koffi Amégbor, Ekoue David Dosseh
This study is a report on a case of papillary carcinoma of the kidney revealed by an abdominal contusion. The results of radiological investigations were discordant with the low intensity of the shock. The treatment consisted of radical nephrectomy because of the suspicion of a pre-existing malignancy. Histological analysis revealed a papillary carcinoma pT3N0M0. We focus on the need for performing diagnostic tests in order to avoid missing a pre-existing anomaly to the kidney trauma.
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28436368/-pseudo-pseudoaneurysm-following-robotic-assisted-partial-nephrectomy
#14
Eric Schommer, Julio Gundian, David D Thiel
A 65-year-old female presented to clinic requesting follow up for a history of right robotic partial nephrectomy done at an outside institution 2 years prior. Initial pathology demonstrated a grade 2/4 3.4 cm clear cell renal cell carcinoma with negative margins. There was no tumor necrosis, sarcomatoid differentiation, or lymphovascular invasion. High quality follow up imaging initially revealed a pseudoaneurysm in the central portion of the right kidney. The patient was sent to interventional radiology for angioembolization...
April 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28429452/real-world-experience-of-the-feasibility-and-tolerability-of-the-2-1-dosing-schedule-with-sunitinib-in-the-treatment-of-patients-with-advanced-renal-cell-carcinoma-in-australia
#15
Megan Crumbaker, Alexander Guminski, Howard Gurney, Dhanusha Sabanathan, Shirley Wong, Nick Pavlakis
AIM: Sunitinib is a first-line treatment option for metastatic renal cell carcinoma (mRCC) funded by the Australian Pharmaceutical Benefits Scheme. Toxicities are common with the standard schedule leading to alternative dosing schedules to be suggested. We reviewed Australian treatment practices to evaluate the safety and outcomes of patients on a 2 weeks on, 1 week off treatment schedule (2/1). METHODS: We performed a retrospective review of 63 patients with mRCC treated with first-line sunitinib on a 2/1 schedule at four Australian centers...
April 21, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28413382/angiomyolipoma-with-epithelial-cysts-masquerading-as-a-cystic-renal-cell-carcinoma
#16
Andrew Wood, Fiona Young, Marie O'Donnell
Angiomyolipoma with epithelial cysts (AMLEC) is a very uncommon renal tumor. AMLEC has a characteristic histological appearance and immunohistochemical staining pattern, knowledge of which should preclude misdiagnosis by pathologists. We present a rare case of an AMLEC which was suspected to be a cystic renal cell carcinoma radiologically. We describe the characteristic immunological staining pattern and ultrastructural features of this lesion and discuss the potential differential diagnoses.
January 2017: Current Urology
https://www.readbyqxmd.com/read/28376423/a-single-thyroid-nodule-revealing-early-metastases-from-clear-cell-renal-carcinoma-case-report-and-review-of-literature
#17
Marino Di Furia, Andrea Della Penna, Andrea Salvatorelli, Marco Clementi, Stefano Guadagni
INTRODUCTION: We report the case of an incidental solitary renal cancer cell (RCC) thyroid metastatic nodule treated by thyroidectomy. PRESENTATION OF CASE: A 53 year male presented with a solitary, asymptomatic thyroid nodule. He was treated with left nephrectomy 1 year before for a RCC. Radiological standard follow-up was negative for secondary lesions but ultrasound (US) 12 months after surgery revealed a 1.5cm solid nodule in the right lobe of the gland. Fine needle aspiration biopsy (FNAB) was inadequate and the patient was submitted to total thyroidectomy...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28286335/challenging-pitfalls-and-mimickers-in-diagnosing-anastomosing-capillary-hemangioma-of-the-kidney-case-report-and-literature-review
#18
REVIEW
Haneen Adnan Al-Maghrabi, Abdullatif Sami Al Rashed
BACKGROUND Vascular tumors of the kidney are rare tumors that are usually diagnosed and confirmed by histopathological examination due to the difficulty in definitive diagnosis by clinical and radiological examination. Anastomosing hemangioma is a rare variant of capillary hemangioma that mimics angiosarcoma. CASE REPORT Here, we present a case of a 55-year-old female with a history of partial nephrectomy due to clear cell renal cell carcinoma three years earlier, who presented with a contralateral anastomosing capillary hemangioma...
March 13, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28274620/partial-nephrectomy-is-associated-with-higher-risk-of-relapse-compared-with-radical-nephrectomy-for-clinical-stage-t1-renal-cell-carcinoma-pathologically-up-staged-to-t3a
#19
Paras H Shah, Daniel M Moreira, Vinay R Patel, Geoffrey Gaunay, Arvin K George, Manaf Alom, Zachary Kozel, Oksana Yaskiv, Simon J Hall, Michael J Schwartz, Manish A Vira, Lee Richstone, Louis R Kavoussi
PURPOSE: We studied recurrence-free survival after partial vs radical nephrectomy for clinical stage T1 renal cell carcinoma in all patients and in those up staged to pathological stage T3a. MATERIALS AND METHODS: We retrospectively reviewed the records of 1,250 patients who underwent partial or radical nephrectomy for clinically localized T1 renal cell carcinoma between 2006 and 2014. Recurrence-free survival was estimated using the Kaplan-Meier method and evaluated as a function of nephrectomy type with the log rank test and Cox models, adjusting for clinical, radiological and pathological characteristics...
March 6, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28268233/does-computed-tomography-still-have-limitations-to-distinguish-benign-from-malignant-renal-tumors-for-radiologists
#20
Toshitaka Shin, Vinay A Duddalwar, Osamu Ukimura, Toru Matsugasumi, Frank Chen, Nariman Ahmadi, Andre Luis de Castro Abreu, Hiromitsu Mimata, Inderbir S Gill
OBJECTIVES: To evaluate the current accuracy of CT for diagnosing benign renal tumors. MATERIALS AND METHODS: We retrospectively reviewed 905 patients who underwent preoperative CT followed by surgical resection. The final pathology was benign in 156 patients (17%). After exclusions, 140 patients with 163 benign tumors were included and 3 sets of the CT interpretations by radiologists with varying levels of experience were analyzed. RESULTS: The histological breakdown was as follows: oncocytomas (54...
March 8, 2017: Urologia Internationalis
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