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https://www.readbyqxmd.com/read/27932857/vogt-koyanagi-harada-syndrome-current-perspectives
#1
REVIEW
Abeir Baltmr, Sue Lightman, Oren Tomkins-Netzer
Vogt-Koyanagi-Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27930434/occult-globe-perforation-during-medial-canthopexy
#2
Deepa Manjunath, Peter K Kaiser, Justis P Ehlers
PURPOSE: To report a case of occult globe perforation following craniofacial surgery. METHODS: A 16-year-old girl presented with vision loss and hypotony of her left eye following a craniofacial procedure, including bilateral medial canthopexy. This report describes the evaluation and findings following the craniofacial surgery. RESULTS: After recognition of vision loss and concern for rupture, surgical exploration was performed by an ophthalmologist at an outside institution on suspicion of globe penetration/perforation...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27913442/comparison-of-anti-vegf-therapies-on-fibrovascular-pigment-epithelial-detachments-in-age-related-macular-degeneration
#3
Adrian Au, Vishal S Parikh, Rishi P Singh, Justis P Ehlers, Alex Yuan, Aleksandra V Rachitskaya, Jonathan E Sears, Sunil K Srivastava, Peter K Kaiser, Andrew P Schachat, Daniel F Martin, Yasha Modi
BACKGROUND: The aim is to compare the therapeutic effects of three antivascular endothelial growth factor (VEGF) drugs (bevacizumab, aflibercept and ranibizumab) on fibrovascular pigment epithelial detachments (fvPEDs) in age-related macular degeneration (AMD). METHODS: This was a retrospective, comparative, consecutive case series of 88 unique eyes with fvPEDs in neovascular AMD treated with anti-VEGF monotherapy for a minimum of 6 months. All eyes were treatment naive...
December 2, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27902541/central-serous-chorioretinopathylike-mimicking-multifocal-vitelliform-macular-dystrophy-an-ocular-side-effect-of-mitogen-extracellular-signal-regulated-kinase-inhibitors
#4
Chiara Giuffrè, Elisabetta Miserocchi, Giulio Modorati, Adriano Carnevali, Alessandro Marchese, Lea Querques, Giuseppe Querques, Francesco Bandello
PURPOSE: To describe a case of multiple detachments of the neurosensory retina mimicking multifocal vitelliform macular dystrophy after chemotherapy with mitogen/extracellular signal-regulated kinase inhibitor for metastatic ovarian cancer. METHODS: Case report. RESULTS: A 38-year-old woman presented to our clinic for eye examination before the initiation of chemotherapy with trametinib. One month after starting treatment, the patient complained of vision loss and metamorphopsia in both eyes...
November 29, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27893621/choroidal-changes-associated-with-serous-macular-detachment-in-eyes-with-staphyloma-dome-shaped-macula-or-tilted-disk-syndrome
#5
Anna C S Tan, Suzanne Yzer, K Bailey Freund, Kunal K Dansingani, Nopasak Phasukkijwatana, David Sarraf
PURPOSE: To study the relationship of choroidal abnormalities with serous retinal detachment (SRD) in eyes with staphyloma, dome-shaped macula, or tilted disk syndrome. METHODS: Group 1, 28 eyes of 20 patients with staphyloma/dome-shaped macula/tilted disk syndrome associated with SRD was compared with Group 2, 30 eyes of 20 patients, with staphyloma/dome-shaped macula/tilted disk syndrome but without SRD. Radial and en-face optical coherence tomography and choroidal analysis were performed...
November 23, 2016: Retina
https://www.readbyqxmd.com/read/27887794/retinoschisis-and-neurosensory-detachment-in-advanced-focal-glaucoma
#6
E Arranz-Márquez, E Jarrín Hernández, A Pastor, J García Gil de Bernabé
CLINICAL CASE: A 71-year-old woman with normotensive primary open-angle glaucoma presented with an asymptomatic temporal peripapillary retinoschisis, associated with serous retinal detachment in the eye with the more advanced glaucoma. It was located at the inferior pole of the optic disc, in the proximity of a glaucomatous focal disc defect. DISCUSSION: Although congenital optic pits are strongly related with juxta-papillary retinoschisis, retinoschisis can also arise from acquired defects in the proximity of glaucomatous optic discs...
November 22, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27872777/optic-disk-pit-with-sudden-central-visual-field-scotoma
#7
Nikol Panou, Demetrios G Vavvas
Purpose. To describe a case of optic disk pit (ODP) with sudden central visual field scotoma. Methods. A 49-year-old woman presented, reporting sudden painless central visual field loss 3 months prior to presentation. Neuroophthalmologic, systematic, and laboratory evaluation and full imaging processes were performed. Results. Fundoscopy and color photography demonstrated an optic disk pit inferotemporally. Perimetry identified central visual field horizontal scotoma. OCT revealed absence of serous retinal detachment, but disclosed inner retina thinning corresponding to the area of the visual field loss...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27861254/bilateral-diffuse-uveal-melanocytic-proliferation-associated-with-renal-cancer-the-importance-of-indocyanine-green-angiography-and-early-diagnosis
#8
Vinicius F Kniggendorf, Elmar T Neto, Elizabeth M Maia, Joao P S Grando, Anne M C Bardal, Patrícia M M Beato, Caroline C Torres, Mauricio Maia
PURPOSE: To report a case of bilateral diffuse uveal melanocytic proliferation associated with renal carcinoma and to illustrate the importance of ancillary examinations to early diagnosis and treatment. DESIGN: Clinical case report. METHODS: A 56-year-old man reported a 3-day history of visual impairment and scotoma in the right eye. An ophthalmoscopic examination, visual field test, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, optical coherence tomography, and systemic evaluation were performed...
November 17, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27847643/novel-perspectives-on-swept-source-optical-coherence-tomography
#9
REVIEW
Fabio Lavinsky, Daniel Lavinsky
Technologies for multimodal digital imaging of vitreoretinal diseases have improved the accuracy of diagnosis and the depth of the knowledge of the mechanisms of disease and their response to treatments. Optic coherence tomography (OCT) has become a mandatory tool for the management and for the follow-up of retinal pathologies. OCT technology evolved in the last two decades from time-domain to spectral domain and recently to the swept-source OCTs (SS-OCT). SS-OCT improved the depth of imaging and the scan speed, thus adding novel algorithms and features such as for vitreous and vitreoretinal interface evaluation, choroid segmentation and mapping, OCT angiography and En-face OCT...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27847640/choroidal-thickness-in-older-patients-with-central-serous-chorioretinopathy
#10
Caio V Regatieri, Eduardo A Novais, Lauren Branchini, Mehreen Adhi, Emily D Cole, Ricardo Louzada, Mark Lane, Elias Reichel, Jay S Duker
BACKGROUND: To investigate the choroidal thickness in older patients with central serous chorioretinopathy (CSCR) compared to age-matched normal subjects. METHODS: Fifteen patients (30 eyes) with CSCR, all aged ≥60 years, and 21 age-matched normal subjects (21 eyes) underwent high-definition raster scanning using SD-OCT. Both eyes from CSCR patients were included in the analysis. The eyes in patients with CSCR were divided into two groups: active CSCR (17 eyes) if there was foveal-involving subretinal fluid and inactive contralateral eye group (13 eyes)...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27822434/seven-year-evaluation-of-idiopathic-multiple-retinal-pigment-epithelium-detachments
#11
Pawel Krasnicki, Diana Dmuchowska, Ewa Zukowska, Zofia Mariak
Objective: To analyze a 7-year natural history of idiopathic multiple retinal pigment epithelium (RPE) detachment based on optical coherence tomography (OCT) images. Methods: Case report. SD-OCT imaging (Topcon 3D OCT-1000). Results: A 55-year-old female presented with three foci of pigment epithelium detachment (PED) in her left eye. Her past ophthalmic and medical history was uneventful. The patient's visual acuity in both eyes was 1.0 throughout the follow-up period. Fluorescein angiography images are shown...
2016: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/27800247/bilateral-vision-loss-after-delivery-in-two-cases-severe-preeclampsia-and-hellp-syndrome
#12
Gökhan Çelik, Ahmet Eser, Murat Günay, Nursal Melda Yenerel
Two patients with no symptoms of hypertension in their medical history before pregnancy were referred to the obstetrics emergency clinic with hypertension and visual complaints. After physical examination and laboratory tests, one of the patients was diagnosed with severe preeclampsia while the other was diagnosed with HELLP syndrome (Hemolysis-Elevated Liver enzymes-Low Platelets). Ocular examinations were performed after delivery due to the patients' worsening visual complaints. The severe preeclamptic patient showed bilateral serous retinal detachment (SRD) while the patient with HELLP syndrome showed bilateral macular hemorrhage...
December 2015: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27799745/pathophysiology-of-visual-disorders-induced-by-phosphodiesterase-inhibitors-in-the-treatment-of-erectile-dysfunction
#13
REVIEW
Marilita M Moschos, Eirini Nitoda
AIM: The aim of this review was to summarize the ocular action of the most common phosphodiesterase (PDE) inhibitors used for the treatment of erectile dysfunction and the subsequent visual disorders. METHOD: This is a literature review of several important articles focusing on the pathophysiology of visual disorders induced by PDE inhibitors. RESULTS: PDE inhibitors have been associated with ocular side effects, including changes in color vision and light perception, blurred vision, transient alterations in electroretinogram (ERG), conjunctival hyperemia, ocular pain, and photophobia...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27795862/malignant-hypertensive-retinopathy-in-an-infant-with-mid-aortic-occlusion
#14
Lawrence J Oh, Gaurav Bhardwaj, David S Winlaw, Craig E Donaldson
Purpose. Case report describing an eight-month-old infant presenting with intermittent esotropia and irritability who was found to have malignant (grade 4) hypertensive retinopathy and mid-aortic syndrome. Methods. Visual acuity was 6/140 in the right eye and not recordable in the left eye. Blood pressure was as high as 230/120 mmHg. Fundoscopy revealed bilateral optic disc swelling, macular stars, and serous retinal detachment in the left eye, findings that are consistent with malignant (grade 4) hypertensive retinopathy...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27780183/dome-shaped-maculopathy-enhanced-visualization-with-radial-optical-coherence-tomography-scans
#15
Joseph G Christenbury, Nopasak Phasukkijwatana, Anna Tan, K Bailey Freund, David Sarraf
PURPOSE: To describe two cases of dome-shaped macula (DSM) and serous macular detachment, the diagnosis of which was enhanced with a radial optical coherence tomography (OCT) scanning protocol. METHODS: Retrospective case series of DSM associated with serous macular detachment. Multimodal retinal imaging was performed including spectral domain OCT with a radial scan protocol and en face OCT angiography. Anatomical outcomes before and after therapy are presented...
September 30, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27778454/quantification-of-fluid-resorption-from-diabetic-macular-oedema-with-foveal-serous-detachment-after-dexamethasone-intravitreal-implant-ozurdex-%C3%A2-in-a-pregnant-diabetic
#16
Delila Hodzic-Hadzibegovic, Shakoor Ba-Ali, Marianne Valerius, Henrik Lund-Andersen
PURPOSE: To quantify the fluid resorption from the centre of the fovea in a pregnant woman with diabetic macular oedema by daily optical coherence tomography (OCT) measurements after the administration of intravitreal dexamethasone implant (Ozurdex(®) ). METHODS: A 36-year-old pregnant woman with type 1 diabetes for 33 years presented with diabetic macular oedema with foveal serous detachment and symptomatic vision loss at 16 gestational weeks. Best-corrected visual acuity (BCVA) in Snellen notation and central retinal volume assessed by optical coherence tomography (OCT, Topcon Corporation) were measured almost on a daily basis the first five weeks after implantation and then 2-3 times per month until childbirth...
October 24, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27747120/full-thickness-macular-hole-formation-after-internal-limiting-membrane-peeling-beware-the-omega-sign
#17
Robert A Sisk, Okan Toygar
Purpose. To introduce a clinical sign on spectral domain optical coherence tomography (SDOCT), which may indicate high risk for full-thickness macular hole formation after internal limiting membrane (ILM) peeling. Methods. The preoperative SDOCT images of two patients-one with multilaminar hemorrhage from ruptured retinal artery macroaneurysm and one with serous retinal detachment and severe macular schisis from optic pit maculopathy-who developed full-thickness macular hole (FTMH) after ILM peeling were evaluated retrospectively...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27734587/canine-panuveitis-a-retrospective-evaluation-of-55-cases-2000-2015
#18
Benjamin E Bergstrom, Jean Stiles, Wendy M Townsend
OBJECTIVE: To determine the most common etiologies of panuveitis in a group of dogs, patient response to therapy, and visual outcome. DESIGN: Retrospective study. MATERIALS AND METHODS: Medical records of 55 dogs diagnosed with panuveitis at the Purdue University Veterinary Teaching Hospital between December 2000 and December 2015 were reviewed. Data collected included signalment, season of diagnosis, descriptions of ocular lesions, diagnostic testing, treatment protocols, etiologic diagnoses (when determined), and visual outcome...
October 12, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27734134/-is-histamine-involved-in-the-formation-of-serous-macular-retinal-detachment
#19
K Kirschfeld
No abstract text is available yet for this article.
October 12, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27730294/-antihistamines-for-the-treatment-of-serous-macular-retinal-detachment
#20
A Hassenstein
No abstract text is available yet for this article.
October 11, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
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