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https://www.readbyqxmd.com/read/29450378/ocular-posterior-pole-pathological-modifications-related-to-complicated-pregnancy-a-review
#1
REVIEW
Vanessa Andrada Păun, Zamfir-Radu Ionescu, Liliana Voinea, Monica Cîrstoiu, Alexandru Baroș, Ștefan Pricopie, Radu Ciuluvică
Ocular posterior pole modification are a pathological manifestation in complicated pregnancies, especially when pregnancy induced hypertension is present (PIH), as well as in preeclampsia (PE) or eclampsia. Nonetheless, as the pregnancy evolves, the possibility for an aggravated evolution with HELLP syndrome, disseminated intravascular coagulation, and idiopathic thrombocytopenic purpura may have an ocular manifestation that, mainly, implies a loss of visual field or acuity, that, left unattended, may constitute a permanent impairment...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29445945/spectral-domain-optical-coherence-tomography-and-fundus-autofluorescence-findings-in-cytomegalovirus-retinitis-in-hiv-infected-patients
#2
Shigeko Yashiro, Takeshi Nishijima, Yuuka Yamamoto, Yumi Sekine, Natsuyo Yoshida-Hata, Tomohiro Iida, Shinichi Oka
PURPOSE: To assess the usefulness of spectral domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) findings in cytomegalovirus (CMV) retinitis. STUDY DESIGN: Observational case series. METHODS: Thirteen eyes of 11 human immunodeficiency virus (HIV)-positive patients with CMV retinitis underwent full ophthalmologic examinations, SD-OCT, and 4 eyes of 4 patients underwent FAF. FAF images included short-wavelength autofluorescence (SW-AF) and near-infrared autofluorescence (IR-AF)...
February 14, 2018: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29443367/swept-source-oct-angiography-of-multiple-evanescent-white-dot-syndrome-with-inflammatory-retinal-pigment-epithelial-detachment
#3
Swarup S Swaminathan, Fang Zheng, Andrew R Miller, Giovanni Gregori, Janet L Davis, Philip J Rosenfeld
A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29403592/management-of-retinal-diseases-in-pregnant-patients
#4
REVIEW
Julie M Rosenthal, Mark W Johnson
Pregnancy leads to significant changes in the body, which potentially affect the retina. Pregnancy can induce disease, such as that seen in hypertensive retinopathy and choroidopathy. It can cause exudative retinal detachments in the HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), disseminated intravascular coagulation (DIC), and thrombotic thrombocytopenic purpura (TTP), and provoke arterial and venous retinal occlusive disease. Pregnancy may also exacerbate pre-existing retinal disease, such as idiopathic central serous chorioretinopathy (ICSC) and diabetic retinopathy...
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29398239/unusual-ocular-clinical-manifestation-of-leptospirosis
#5
V M Asensio-Sánchez, B Haro-Álvarez, J Herreras, A Martín-Prieto
CLINICAL CASE: An uncommon case is presented of a 15 year-old girl with bilateral, multiple serous detachments of retina and retinal pigment epithelium. With clinical and laboratory (IgG 1/160 and IgM 1/160, using an indirect immunofluorescence assay) diagnoses of leptospirosis, a complete ophthalmic examination, fluorescein angiography, autofluorescence and optical coherence tomography were performed, and the patient was followed for two years. DISCUSSION: Bilateral, multiple serous detachments of retina and retinal pigment epithelium can be a complication of systemic leptospirosis, a zoonotic disease caused by Leptospira...
February 1, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29398236/acute-bilateral-serous-central-chorioretinopathy-after-emergency-contraceptive-therapy-with-ulipristal-acetate
#6
J C Molina Martín, M Balboa Alonso, J García Sánchez, M González Herrera, J R Hueso Abancens, E Mengual Verdú
CASE REPORT: The case concerns a 31 year-old woman with no previous history who consulted due to decreased vision in both eyes. She mentioned taking 1 pill of ulipristal acetate (30mg) as an emergency contraceptive four days before the visual symptoms appeared. In the examination, a better corrected visual acuity of 0.6 was found in the right eye and 0.8 in left eye (by Snellen chart), and bilateral macular serous detachment. It was decided to observe, and 15 days later she showed a functional and anatomical improvement...
February 1, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29375706/gamma-knife-perfexion%C3%A2-radiosurgery-and-endo-diode-laser-thermotherapy-for-choroidal-melanoma-with-technical-analysis-a-case-report
#7
Yi-Chieh Tsai, Chun-Yuan Kuo, Jia-Wei Lin, Shun-Tai Yang, Shih-Chung Lai, Jo-Ting Tsai
Radiosurgery serves an important function in the treatment of patients with intraocular tumors and preserves visual function via organ conservation. Therefore, it is important to ensure the safety and precision of GK-SRS as a primary treatment for intraocular tumors. The present case study described a 57-year-old female with uveal melanoma treated with GK-SRS. Retrobulbar anesthesia following fixation of the treated eye, via the suture of two of the extraocular muscles to the stereotactic frame, was performed to immobilize the eye during treatment...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29374647/acute-retinal-detachment-induced-by-the-valsalva-manoeuvre-in-morning-glory-disc-anomaly
#8
Mark A P Fajgenbaum, Serafeim N Antonakis, Luke Membrey, David A Laidlaw
We present a case in which a large, bullous, predominantly inferior, serous retinal detachment developed acutely after the Valsalva manoeuvre (from a coughing fit) in an eye with morning glory disc anomaly. We postulate that a rapid alteration in intracranial pressure was transmitted through the cavitary disc defect. This allowed a sudden influx of cerebrospinal fluid and/or liquefied vitreous into the subretinal space. This previously unreported case provides important evidence for the role of intracranial pressure fluctuations in the pathogenesis of macular schisis and neurosensory detachment secondary to optic disc cavitations...
January 26, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29359109/proteome-and-metabolome-of-subretinal-fluid-in-central-serous-chorioretinopathy-and-rhegmatogenous-retinal-detachment-a-pilot-case-study
#9
Laura Kowalczuk, Alexandre Matet, Marianne Dor, Nasim Bararpour, Alejandra Daruich, Ali Dirani, Francine Behar-Cohen, Aurélien Thomas, Natacha Turck
Purpose: To investigate the molecular composition of subretinal fluid (SRF) in central serous chorioretinopathy (CSCR) and rhegmatogenous retinal detachment (RRD) using proteomics and metabolomics. Methods: SRF was obtained from one patient with severe nonresolving bullous CSCR requiring surgical subretinal fibrin removal, and two patients with long-standing RRD. Proteins were trypsin-digested, labeled with Tandem-Mass-Tag and fractionated according to their isoelectric point for identification and quantification by tandem mass spectrometry...
January 2018: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29346241/chronic-central-serous-chorioretinopathy-early-and-late-morphological-and-functional-changes-after-verteporfin-photodynamic-therapy
#10
Pierluigi Iacono, Massimiliano Tedeschi, Barbara Boccassini, Adele Chiaravalloti, Monica Varano, Mariacristina Parravano
PURPOSE: To describe early and late morphological and functional changes in subjects receiving photodynamic therapy (PDT) for chronic central serous chorioretinopathy. METHODS: Patients with chronic central serous chorioretinopathy were prospectively enrolled and received standard PDT. At the baseline examination, each subject underwent complete ophthalmological examination, including best-corrected visual acuity (BCVA) assessment, fluorescein angiography and indocyanine green angiography, spectral domain optical coherence tomography, and microperimetry...
January 16, 2018: Retina
https://www.readbyqxmd.com/read/29342438/vitreoretinal-complications-and-outcomes-in-92-eyes-undergoing-surgery-for-modified-osteo-odonto-keratoprosthesis-a-10-year-review
#11
Pukhraj Rishi, Ekta Rishi, Vishvesh Agarwal, Sridevi Nair, Geetha Iyer, Bhaskar Srinivasan, Shweta Agarwal
PURPOSE: To analyze vitreoretinal (VR) complications and treatment outcomes in eyes undergoing modified osteo-odonto-keratoprosthesis (OOKP) surgery. DESIGN: Retrospective case series. PARTICIPANTS: All patients who underwent modified OOKP (mOOKP) surgery at a tertiary eye-care center from March 2003 to February 2013 were included. METHODS: Medical records were reviewed for relevant medical history, best-corrected visual acuity (BCVA), slit-lamp examination, ultrasound scan, oral examination findings, and VR complications...
January 13, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29342012/diffuse-chorioretinopathy-without-serous-detachment-associated-with-cardiac-transplantation
#12
Michael F Marmor
PURPOSE: To analyze an unusual case of widespread chorioretinopathy after cardiac transplantation for its potential etiology and clinical significance. METHODS: Clinical examinations included widefield and macular color and fundus autofluorescence photography, spectral domain optical coherence tomography, fluorescein angiography and indocyanine green angiography, full-field electroretinography, and Goldmann visual fields. PATIENT: A 44-year-old Hispanic woman was referred to rule out retinitis pigmentosa...
January 16, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29339644/changes-in-central-macular-thickness-and-retinal-nerve-fiber-layer-thickness-in-eyes-with-vogt-koyanagi-harada-disease-a-2-year-follow-up-study
#13
Yong-Seop Han, Kyung-Sup Shin, Woo-Hyuk Lee, Jung-Yeul Kim
PURPOSE: To investigate the central macular thickness (CMT) and retinal nerve fiber layer (RNFL) thickness in eyes with Vogt-Koyanagi-Harada (VKH) disease associated with optic disc swelling and serous retinal detachment through a 24-month follow-up period. METHODS: We prospectively investigated 28 eyes of 14 treatment-naïve patients with acute VKH disease associated with optic disc swelling and serous retinal detachment and 30 eyes of 15 normal individuals to compare changes in the CMT and average RNFL thickness...
January 16, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29338130/correlation-between-morphological-characteristics-in-spectral-domain-optical-coherence-tomography-different-functional-tests-and-a-patient-s-subjective-handicap-in-acute-central-serous-chorioretinopathy
#14
Bianca S Gerendas, Julia-Sophie Kroisamer, Wolf Buehl, Sandra M Rezar-Dreindl, Katharina M Eibenberger, Eleonore Pablik, Ursula Schmidt-Erfurth, Stefan Sacu
PURPOSE: The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical practice. METHODS: Retinal thickness (RT), the height, area and volume of subretinal fluid (SRF)/pigment epithelium detachments were evaluated using the standardized procedures of the Vienna Reading Center...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29321438/vogt-koyanagi-harada-disease-associated-with-influenza-a-virus-infection-a-case-report
#15
Nozomu Yoshino, Ai Kawamura, Akira Ishii, Katsuyuki Yoshida, Tamami Watanabe, Takeshi Yamashita, Takahiko Fukuchi, Fumihiko Toyoda, Akihiko Kakehashi, Hitoshi Sugawara
We herein report a case of a 31-year-old Japanese man who simultaneously had a positive influenza A virus antigen test result and Vogt-Koyanagi-Harada disease (VKHD), demonstrated by both diffuse multiple early hyperfluorescent points on fluorescein fundus photography and serous retinal detachments on optical coherence tomography. He had meningitis. It was difficult to determine whether the main cause of meningitis was influenza A or VKHD. After initial treatment with peramivir for influenza A and then methylprednisolone pulse with subsequent corticosteroid therapy for VKHD, his symptoms improved gradually...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29282403/epiretinal-membrane-in-dome-shaped-macula-complicated-with-serous-retinal-detachment-transient-efficacy-of-surgery
#16
Guillaume Soudier, Alain Gaudric, Vincent Gualino, Mathieu Nardin, Claude Speeg-Schatz, David Gaucher
Dome-shaped macula (DSM) is an entity recently described as a convex anterior protrusion of the macular area within a posterior myopic staphyloma. Specific complications were associated with DSM, like serous retinal detachment (SRD). We describe a woman presenting with a decreased vision at 20/50. SD-OCT scans were performed, showing a macular bulge. SRD was present and an epiretinal membrane could also be observed. Fluorescein angiography and indocyanin green angiography did not show any leakage nor choroidal neovascularization...
September 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29260086/retinal-findings-in-membranoproliferative-glomerulonephritis
#17
Ahmad M Mansour, Luiz H Lima, J Fernando Arevalo, Miguel Hage Amaro, Virginia Lozano, Alaa Bou Ghannam, Errol W Chan
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed for a period of 1.5-37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment...
September 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29212288/failure-of-ocular-photodynamic-therapy-for-secondary-choroidal-metastasis-a-case-report-and-literature-review
#18
Rui Hua, Wenya Li, Weiwei Wu, Jun Tao, Qing Peng
The choroid is the most common site for intraocular metastatic disease. Photodynamic therapy (PDT) can effectively destroy malignant tissue and induce anti-tumor activity. Recent publications support its use as an effective therapy for the treatment of choroidal metastases, especially in the subfoveal region, resulting in subsequent vision preservation or improvement. Here, we introduce a case of choroidal metastasis, secondary to primary lung cancer. The progression of choroidal metastasis after PDT was followed up using spectral domain optical coherence tomography with point-to-point follow-up...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29195497/bilateral-uveitis-and-macular-edema-induced-by-nivolumab-a-case-report
#19
Claire Theillac, Morgane Straub, Anne-Laure Breton, Luc Thomas, Stéphane Dalle
BACKGROUND: Nivolumab is a fully human antibody which is routinely used at first therapy for metastatic melanoma. Usually, side effects are immune-related adverse events. We report a case of a man who developed bilateral anterior uveitis and macular serous retinal detachment during nivolumab treatment for metastatic melanoma. CASE PRESENTATION: A man on nivolumab treatment for a leg melanoma with duodenal and lymph nodes metastases developed a sudden bilateral visual acuity impairment and bilateral non-painfull redness eyes several days after the third infusion...
December 1, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29190243/factors-associated-with-serous-retinal-detachment-in-highly-myopic-eyes-with-vertical-oval-shaped-dome
#20
Antonio García-Ben, María J Morillo Sanchez, Ana Gonzalez Gómez, Ignacio García-Basterra, Antonio Soler García, Jose M García-Campos
PURPOSE: This study investigated factors associated with persistent serous retinal detachment in highly myopic eyes with vertical oval-shaped domes. METHODS: Twenty-eight highly myopic patients (40 eyes) with smooth macular elevations related to a vertical oval-shaped dome were recruited. Serous retinal detachment was investigated; 11 eyes had persistent submacular fluid (study group) and 29 eyes lacked submacular fluid (control group). All patients underwent complete ophthalmologic examinations, including axial-length measurement and fluorescein angiography...
November 22, 2017: Retina
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