keyword
MENU ▼
Read by QxMD icon Read
search

Coxiella

keyword
https://www.readbyqxmd.com/read/28319680/first-genetic-evidence-of-coxiella-burnetii-in-cases-presenting-with-acute-febrile-illness-india
#1
Sanjay Kumar, Shefali Raj Gangoliya, Syed Imteyaz Alam, Satish Patil, Ganavalli Subramanya Ajantha, Raghavendra Dhirendra Kulkarni, Dev Vrat Kamboj
No abstract text is available yet for this article.
March 20, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28293541/high-content-imaging-reveals-expansion-of-the-endosomal-compartment-during-coxiella-burnetii-parasitophorous-vacuole-maturation
#2
Charles L Larson, Robert A Heinzen
Coxiella burnetii is an obligate intracellular pathogen and the causative agent of human Q fever. Replication of the bacterium within a large parasitophorous vacuole (PV) resembling a host phagolysosome is required for pathogenesis. PV biogenesis is a pathogen driven process that requires engagement of several host cell vesicular trafficking pathways to acquire vacuole components. The goal of this study was to determine if infection by C. burnetii modulates endolysosomal flux to potentially benefit PV formation...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28290594/-effects-of-vaccination-against-q-fever-in-lower-saxony-dairy-cattle-farms
#3
Stefanie Lehner, Katja Lohan, Heinz-Josef Dieckhoff, Ursula Gerdes
OBJECTIVE: Being a notifiable and zoonotic disease, Q-fever is coming under increasing focus of epizootic disease control. Current studies indicate that the disease is more widespread in Germany than the number of notifications suggest. Therefore, since 2013, under certain conditions a hardship allowance is granted by the Animal Diseases Fund of Lower Saxony for the vaccine costs of the basic immunization to support affected farms. Material und methods: All farmers, on whose farms clinical signs of Q-fever and the pathogen Coxiella burnetii had been detected prior to vaccination and who had taken advantage of the hardship allowance during the previous 2 years were surveyed to assess the effectiveness of the measure...
March 14, 2017: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/28284601/molecular-investigation-into-the-presence-of-a-coxiella-sp-in-rhipicephalus-sanguineus-ticks-in-australia
#4
Charlotte L Oskam, Alexander W Gofton, Telleasha L Greay, Rongchang Yang, Stephen Doggett, Una M Ryan, Peter J Irwin
Q fever is an infectious disease with a global distribution caused by the intracellular bacterium, Coxiella burnetii, which has been detected in a large number of tick species worldwide, including the brown dog tick, Rhipicephalus sanguineus. Recent reports of a high seroprevalance of C. burnetii in Australian dogs, along with the identification of additional Coxiella species within R. sanguineus ticks, has prompted an investigation into the presence and identification of Coxiella species in R. sanguineus ticks in Australia...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28281305/evolutionary-changes-in-symbiont-community-structure-in-ticks
#5
Olivier Duron, Florian Binetruy, Valérie Noël, Julie Cremaschi, Karen D McCoy, Céline Arnathau, Olivier Plantard, John Goolsby, Adalberto A Pérez de León, Dieter J A Heylen, A Raoul Van Oosten, Yuval Gottlieb, Gad Baneth, Alberto A Guglielmone, Agustin Estrada-Peña, Maxwell N Opara, Lionel Zenner, Fabrice Vavre, Christine Chevillon
Ecological specialization to restricted diet-niches is driven by obligate, and often maternally inherited, symbionts in many arthropod lineages. These heritable symbionts typically form evolutionarily stable associations with arthropods that can last for millions of years. Ticks were recently found to harbor such an obligate symbiont, Coxiella-LE, that synthesizes B vitamins and cofactors not obtained in sufficient quantities from blood diet. In this study, the examination of 81 tick species show that some Coxiella-LE symbioses are evolutionarily stable with an ancient acquisition followed by co-diversification as observed in ticks belonging to the Rhipicephalus genus...
March 9, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28278296/robust-growth-of-avirulent-phase-ii-coxiella-burnetii-in-bone-marrow-derived-murine-macrophages
#6
Diane C Cockrell, Carrie M Long, Shelly J Robertson, Jeffrey G Shannon, Heather E Miller, Lara Myers, Charles L Larson, Tregei Starr, Paul A Beare, Robert A Heinzen
Published data show that murine bone marrow-derived macrophages (BMDM) restrict growth of avirulent phase II, but not virulent phase I, Coxiella burnetii. Growth restriction of phase II bacteria is thought to result from potentiated recognition of pathogen-associated molecular patterns, which leads to production of inhibitory effector molecules. Past studies have used conditioned medium from L-929 murine fibroblasts as a source of macrophage-colony stimulating factor (M-CSF) to promote differentiation of bone marrow-derived myeloid precursors into macrophages...
2017: PloS One
https://www.readbyqxmd.com/read/28274243/presence-of-coxiella-burnetii-dna-in-inflamed-bovine-cardiac-valves
#7
Jørgen S Agerholm, Tim K Jensen, Jens F Agger, Marc Y Engelsma, Hendrik I J Roest
BACKGROUND: Bacterial endocarditis is a recognised disease in humans and animals. In humans, infection with Coxiella burnetii can cause endocarditis, but this has not been investigated thoroughly in animals. Endocarditis in cattle is a common post-mortem finding in abattoirs and studies have identified Trueperella pyogenes as a major cause. Despite exposure of cattle to C. burnetii, the significance of this particular bacterium for development and progression of endocarditis has not been studied in detail...
March 9, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28272921/prevalence-and-risk-factors-of-coxiella-burnetii-antibodies-in-bulk-milk-from-cattle-sheep-and-goats-in-jordan
#8
Mohammad M Obaidat, Gilbert J Kersh
This large-scale cross-sectional study was conducted to determine the prevalence, geographical distribution, and risk factors for the presence of antibodies against Coxiella burnetii in bulk tank milk derived from dairy cattle, sheep, and goats in Jordan. Bulk milk samples were collected from 78 dairy cattle, 48 sheep, and 23 goat farms from various places in Jordan according to the density of these animal species in each region of the country. The samples were tested for C. burnetii antibodies using the CHEKIT Q-Fever Antibody ELISA kit...
March 8, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28267780/the-eurasian-otter-lutra-lutra-as-a-potential-host-for-rickettsial-pathogens-in-southern-italy
#9
Mario Santoro, Nicola D'Alessio, Anna Cerrone, Maria Gabriella Lucibelli, Giorgia Borriello, Gaetano Aloise, Clementina Auriemma, Nunzia Riccone, Giorgio Galiero
Canine monocytic ehrlichiosis and rickettsiosis are zoonotic tick-borne diseases of canids caused by the intracellular obligate bacteria Ehrlichia canis and Rickettsia species respectively. In this study, we investigated using standard and real-time PCR and sequencing, the occurrence and molecular characterization of E. canis and Rickettsia species in the Eurasian otter (Lutra lutra) from the southern Italian population. Samples were screened by using molecular assays also for Neospora caninum, Toxoplasma gondii, Clamydophyla spp...
2017: PloS One
https://www.readbyqxmd.com/read/28254833/yellow-fever-vaccine-associated-neurological-disease-a-suspicious-case
#10
Pedro Beirão, Patrícia Pereira, Andreia Nunes, Pedro Antunes
A 70-year-old man with known cardiovascular risk factors, presented with acute onset expression aphasia, agraphia, dyscalculia, right-left disorientation and finger agnosia, without fever or meningeal signs. Stroke was thought to be the cause, but cerebrovascular disease investigation was negative. Interviewing the family revealed he had undergone yellow fever vaccination 18 days before. Lumbar puncture revealed mild protein elevation. Cultural examinations, Coxiella burnetti, and neurotropic virus serologies were negative...
March 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28246364/elevated-cholesterol-in-the-coxiella-burnetii-intracellular-niche-is-bacteriolytic
#11
Minal Mulye, Dhritiman Samanta, Seth Winfree, Robert A Heinzen, Stacey D Gilk
Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome fuses with the host endocytic pathway to form a large lysosome-like vacuole called the parasitophorous vacuole (PV). The PV membrane is rich in sterols, and drugs perturbing host cell cholesterol homeostasis inhibit PV formation and bacterial growth. Using cholesterol supplementation of a cholesterol-free cell model system, we found smaller PVs and reduced Coxiella growth as cellular cholesterol concentration increased...
February 28, 2017: MBio
https://www.readbyqxmd.com/read/28242621/a-farnesylated-coxiella-burnetii-effector-forms-a-multimeric-complex-at-the-mitochondrial-outer-membrane-during-infection
#12
Laura F Fielden, Jennifer H Moffatt, Yilin Kang, Michael James Baker, Chen Ai Khoo, Craig R Roy, Diana Stojanovski, Hayley J Newton
Coxiella burnetii, the causative agent of Q fever, establishes a unique lysosome-derived intracellular niche termed the Coxiella-containing vacuole (CCV). The Dot/Icm type IVB secretion system is essential for biogenesis of the CCV and intracellular replication of Coxiella. Effector proteins, translocated into the host cell through this apparatus, act to modulate host trafficking and signaling processes to facilitate CCV development. Here we investigated the role of CBU0077, a conserved Coxiella effector that had previously been observed to localize to lysosomal membranes...
February 27, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28217558/the-scid-mouse-model-for-identifying-virulence-determinants-in-coxiella-burnetii
#13
Erin J van Schaik, Elizabeth D Case, Eric Martinez, Matteo Bonazzi, James E Samuel
Coxiella burnetii is an intracellular, zoonotic pathogen that is the causative agent of Q fever. Infection most frequently occurs after inhalation of contaminated aerosols, which can lead to acute, self-limiting febrile illness or more serve chronic infections such as hepatitis or endocarditis. Macrophages are the principal target cells during infection where C. burnetii resides and replicates within a unique phagolysosome-like compartment, the Coxiella-containing vacuole (CCV). The first virulence determinant described as necessary for infection was full-length lipopolysaccarride (LPS); spontaneous rough mutants (phase II) arise after passage in immuno-incompetent hosts...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28203574/resolution-of-q-fever-associated-cryoglobulinemia-with-anti-cd20-monoclonal-antibody-treatment
#14
Kellie L Hawkins, Edward N Janoff, Robert W Janson
Immunologic phenomena can complicate chronic infections with Coxiella burnetii (Q fever), including immune complex deposition causing vasculitis, neuropathy, and glomerulonephritis. We describe the case of a man with Q fever endocarditis, mixed cryoglobulinemia, and life-threatening vasculitis driven by immune complex deposition who was successfully treated with B cell depleting therapy (rituximab).
January 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28193163/prevalence-and-clinical-presentation-of-rickettsia-coxiella-leptospira-bartonella-and-chikungunya-virus-infections-among-hospital-based-febrile-patients-from-december-2008-to-november-2009-in-bangladesh
#15
Labib Imran Faruque, Rashid Uz Zaman, Emily S Gurley, Robert F Massung, A S M Alamgir, Renee L Galloway, Ann M Powers, Ying Bai, Michael Kosoy, William L Nicholson, Mahmudur Rahman, Stephen P Luby
BACKGROUND: We conducted a study to identify Rickettsia, Coxiella, Leptospira, Bartonella, and Chikungunya virus infections among febrile patients presenting at hospitals in Bangladesh. METHODS: We collected blood samples from patients at six tertiary hospitals from December 2008 to November 2009 and performed laboratory tests at the United States Centers for Disease Control and Prevention (CDC). RESULTS: Out of 720 enrolled patients, 263 (37%) were infected with Rickettsia; 132 patients had immunofluorescence antibody titer >64 against spotted fever, 63 patients against scrub typhus fever and 10 patients against typhus fever...
February 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28179203/involvement-of-matrix-metalloproteinases-in-chronic-q-fever
#16
Anne F M Jansen, Teske Schoffelen, Julien Textoris, Jean Louis Mege, Chantal P Bleeker-Rovers, Hendrik I J Roest, Peter C Wever, Leo A B Joosten, Mihai G Netea, Esther van de Vosse, Marcel van Deuren
OBJECTIVES: Chronic Q fever is a persistent infection with the intracellular Gram-negative bacterium Coxiella burnetii, which can lead to complications of infected aneurysms. Matrix metalloproteinases (MMPs) cleave extracellular matrix and are involved in infections as well as aneurysms. We aimed to study the role of MMPs in the pathogenesis of chronic Q fever. METHODS: We investigated gene expression of MMPs through microarray analysis and MMP production with enzyme-linked immunosorbent assay in C...
February 4, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28176495/serosurvey-of-coxiella-burnetii-q-fever-in-dromedary-camels-camelus-dromedarius-in-laikipia-county-kenya
#17
A S Browne, E M Fèvre, M Kinnaird, D M Muloi, C A Wang, P S Larsen, T O'Brien, S L Deem
Dromedary camels (Camelus dromedarius) are an important protein source for people in semi-arid and arid regions of Africa. In Kenya, camel populations have grown dramatically in the past few decades resulting in the potential for increased disease transmission between humans and camels. An estimated four million Kenyans drink unpasteurized camel milk, which poses a disease risk. We evaluated the seroprevalence of a significant zoonotic pathogen, Coxiella burnetii (Q fever), among 334 camels from nine herds in Laikipia County, Kenya...
February 8, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28167053/seroprevalence-and-risk-factors-of-coxiella-burnetii-infection-among-high-risk-population-in-center-of-iran-a-neglected-health-problem
#18
Zary Nokhodian, Behrooz Ataei, Abdolreza Moradi, Majid Yaran, Shervin Gaffari Hoseini, Awat Feizi, Roya Sherkat
In order to evaluate the prevalence of antibodies against phase I and II antigens of Coxiella Burnetii and to identify related risk factors among high-risk groups in the center of Iran, a serological survey was performed in Isfahan County. In a cross-sectional study, 401 sera were collected from slaughterhouse workers, butchers, farmers and veterinarians in spring 2015. Samples were tested for specific immunoglobulin G (IgG) antibodies against phase I and II of C. burnetii by indirect immunofluorescence assay...
May 2017: Acta Tropica
https://www.readbyqxmd.com/read/28131376/molecular-evidence-of-tick-borne-hemoprotozoan-parasites-theileria-ovis-and-babesia-ovis-and-bacteria-in-ticks-and-blood-from-small-ruminants-in-northern-algeria
#19
Atef Aouadi, Hamza Leulmi, Mehdi Boucheikhchoukh, Ahmed Benakhla, Didier Raoult, Philippe Parola
Using qPCR, standard PCR and/or sequencing, we investigated the presence of tick-associated microorganisms in ticks and blood from sheep and goats from Souk Ahras, Algeria. Borrelia theileri, was detected in (7/120, 5.8%) blood from sheep and (13/120, 10.8%) goats. Anaplasma ovis was screened in (38/73, 52%) Rhipicephalus bursa and (5/22, 22.7%) R. turanicus and in (74/120, 61.7%), (65/120, 54.2%) blood of sheep and goats respectively. Coxiella burnetii tested positive in R. bursa (4/73, 5.5%) and (7/120, 5...
February 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28131375/transmission-of-coxiella-burnetii-to-cage-mates-using-murine-animal-model
#20
Yassina Bechah, Didier Raoult
Aerosols from the products of abortions of infected animals with Coxiella burnetii were known to be the main source of infection in humans with this bacterium. However, little is known about the excretion of C. burnetii in the feces and urine of infected mice, or the dynamic of transmission between infected and healthy mice. To investigate whether C. burnetii can be excreted in the feces and urine of infected mice and whether transmission to uninfected cage mates occurs, male mice were inoculated with C. burnetii using a "whole body aerosol system" and feces and urine were collected different time points post-infection from these mice...
February 2017: Comparative Immunology, Microbiology and Infectious Diseases
keyword
keyword
10619
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"