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https://www.readbyqxmd.com/read/28108406/berry-s-ligament-and-the-inferior-thyroid-artery-as-reliable-anatomical-landmarks-for-the-recurrent-laryngeal-nerve-a-fresh-cadaveric-study-of-the-cervical-spine-the-recurrent-laryngeal-nerve-rln-relevant-to-spine
#1
Ali Rajabian, Michael Walsh, Nasir A Quraishi
BACKGROUND CONTEXT: Whilst most cadaveric studies of the RLN have focused on course variations, they have usually been done on preserved (fixed and embalmed) cadavers which renders the RLN immobile and of less surgical landmark value. PURPOSE: Our aim was to perform a thorough exposure in fresh cadavers with the intention of investigating inferior thyroid artery and Berry's ligament as reliable landmarks for the identification of the RLN in anterior cervical spine surgery...
January 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28103558/effective-multi-query-expansions-collaborative-deep-networks-based-feature-learning-for-robust-landmark-retrieval
#2
Yang Wang, Xuemin Lin, Lin Wu, Wenjie Zhang
Given a query photo issued by a user (q-user), the landmark retrieval is to return a set of photos with their landmarks similar to those of the query, while the existing studies on the landmark retrieval focus on exploiting geometries of landmarks for similarity matches between candidate photos and a query photo. We observe that the same landmarks provided by different users over social media community may convey different geometry information depending on the viewpoints and/or angles, and may subsequently yield very different results...
January 18, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28093049/efficient-variational-approach-to-multimodal-registration-of%C3%A2-anatomical%C3%A2-and%C3%A2-functional-intra-patient-tumorous-brain-data
#3
Alvar-Ginés Legaz-Aparicio, Rafael Verdú-Monedero, Jorge Larrey-Ruiz, Juan Morales-Sánchez, Fernando López-Mir, Valery Naranjo, Ángela Bernabéu
This paper addresses the functional localization of intra-patient images of the brain. Functional images of the brain (fMRI and PET) provide information about brain function and metabolism whereas anatomical images (MRI and CT) supply the localization of structures with high spatial resolution. The goal is to find the geometric correspondence between functional and anatomical images in order to complement and fuse the information provided by each imaging modality. The proposed approach is based on a variational formulation of the image registration problem in the frequency domain...
November 29, 2016: International Journal of Neural Systems
https://www.readbyqxmd.com/read/28066627/survival-analyses-in-lung-cancer
#4
EDITORIAL
Kari Chansky, Dragan Subotic, Nathan R Foster, Torsten Blum
BACKGROUND: Although survival analyses represent one of the cornerstones in oncology in general, some aspects of the reported survival data in lung cancer patients are still not fully elucidated. METHODS: After having defined several open questions, an evidence based approach was applied in order to answer these questions. Areas of interest were: (I) possible uncertainties in reported survival data; (II) survival surrogates; (III) recommended methods for evaluating progression free survival (PFS) as a surrogate endpoint in future datasets; (IV) postoperative lung cancer recurrence and survival...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28058863/what-should-clinicians-know-about-the-use-of-glucocorticoids-in-systemic-sclerosis
#5
Michele Iudici
Glucocorticoids (GC) are drugs largely used by rheumatologists, but their utilization in systemic sclerosis (SSc) is still controversial for both the lack of evidence of their usefulness and the physicians and patients' concern about their related adverse events. Due to the rarity and the complexity of the disease, few studies investigating the role of GC in SSc have been performed. Thus, a huge variability in corticosteroid prescriptive practice among physicians involved in the care of SSc patients still exists worldwide...
January 6, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28027916/vitamin-d-in-saudi-arabia-prevalence-distribution-and-disease-associations
#6
REVIEW
Nasser M Al-Daghri
More than 33 years have passed since the first paper highlighting vitamin D deficiency as a public health concern in Saudi Arabia was published in 1983. Despite "early" detection,it wasn't until the year 2010 where the interest in vitamin D research grew exponentially worldwide and was finally visible in Saudi clinical and academic areas. Since then,many landmark studies have been generated with regards to the physiologic functions of vitamin D,both skeletal and extra-skeletal. This review is limited to the prevalence,distribution A systematic review on the prevalence studies done in KSA from 2011 to 2016 was done and revealed that the prevalence of vitamin D deficiency (<50nmol/l) in Saudi Arabia among different populations (adults,children and adolescents,newborns and pregnant/lactating women) is 81...
December 24, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28018895/regional-differences-in-end-diastolic-volumes-between-3d-echo-and-cmr-in-hlhs-patients
#7
Alberto Gomez, Ozan Oktay, Daniel Rueckert, Graeme P Penney, Julia A Schnabel, John M Simpson, Kuberan Pushparajah
Ultrasound is commonly thought to underestimate ventricular volumes compared to magnetic resonance imaging (MRI), although the reason for this and the spatial distribution of the volume difference is not well understood. In this paper, we use landmark-based image registration to spatially align MRI and ultrasound images from patients with hypoplastic left heart syndrome and carry out a qualitative and quantitative spatial comparison of manual segmentations of the ventricular volume obtained from the respective modalities...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27999403/monitoring-building-deformation-with-insar-experiments-and-validation
#8
Kui Yang, Li Yan, Guoman Huang, Chu Chen, Zhengpeng Wu
Synthetic Aperture Radar Interferometry (InSAR) techniques are increasingly applied for monitoring land subsidence. The advantages of InSAR include high accuracy and the ability to cover large areas; nevertheless, research validating the use of InSAR on building deformation is limited. In this paper, we test the monitoring capability of the InSAR in experiments using two landmark buildings; the Bohai Building and the China Theater, located in Tianjin, China. They were selected as real examples to compare InSAR and leveling approaches for building deformation...
December 20, 2016: Sensors
https://www.readbyqxmd.com/read/27995390/the-three-decade-long-journey-in-heart-failure-drug-development
#9
Kelly S Lewis, Javed Butler, Johann Bauersachs, Peter Sandner
Heart failure is a global disease with increasing prevalence due to an aging worldwide population with increasing co-morbidities. Despite several therapeutic options available to treat HFrEF, morbidity and mortality remain high. Importantly, no approved therapies are available to treat HFpEF. This paper will briefly summarize the burden of disease, HF classification and definitions and the landmark clinical trials in both HFrEF and HFpEF. Given the increasing incidence and prevalence of HF and the high morbidity and mortality associated with this disease, continued development efforts are essential to address the unmet needs of these patients...
December 20, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27993606/classification-of-navigation-impairment-a-systematic-review-of-neuropsychological-case-studies
#10
REVIEW
Michiel H G Claessen, Ineke J M van der Ham
The neurocognitive architecture of navigation ability has been investigated by extensively studying the navigation problems of individual neurological patients. These neuropsychological case reports have applied highly variable approaches to establish navigation impairment in their patients. This review provides a systematic and up-to-date inventory of all relevant case studies and presents an analysis of the types of navigation impairments that have been described. The systematic literature search revealed 58 relevant papers reporting on 67 neurological patients...
December 16, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27993480/bokhman-redux-endometrial-cancer-types-in-the-21st-century
#11
Adrian A Suarez, Ashley S Felix, David E Cohn
In 1983 Jan V. Bokhman, M.D. published a landmark paper entitled "Two Pathogenetic Types of Endometrial Carcinoma" in which an enduring dualistic view of endometrial cancer was first proposed. "Type I" cancers are thought to represent estrogen driven mostly low grade endometrioid tumors strongly associated with obesity and other components of the metabolic syndrome. "Type II" cancers represent higher grade non-endometrioid tumors for which the latter associations are less significant. Basic tenets of this dichotomy including significant prognostic differences have been abundantly confirmed by later literature...
December 16, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27981065/art-3-5d-an-algorithm-to-label-arteries-and-veins-from-three-dimensional-angiography
#12
Beatrice Barra, Elena De Momi, Giancarlo Ferrigno, Guglielmo Pero, Francesco Cardinale, Giuseppe Baselli
Preoperative three-dimensional (3-D) visualization of brain vasculature by digital subtraction angiography from computerized tomography (CT) in neurosurgery is gaining more and more importance, since vessels are the primary landmarks both for organs at risk and for navigation. Surgical embolization of cerebral aneurysms and arteriovenous malformations, epilepsy surgery, and stereoelectroencephalography are a few examples. Contrast-enhanced cone-beam computed tomography (CE-CBCT) represents a powerful facility, since it is capable of acquiring images in the operation room, shortly before surgery...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27959801/webly-supervised-fine-grained-visual-categorization-via-deep-domain-adaptation
#13
Zhe Xu, Shaoli Huang, Ya Zhang, Dacheng Tao
Learning visual representations from web data has recently attracted attention for object recognition. Previous studies have mainly focused on overcoming label noise and data bias and have shown promising results by learning directly from web data. However, we argue that it might be better to transfer knowledge from existing human labeling resources to improve performance at nearly no additional cost. In this paper, we propose a new semi-supervised method for learning via web data. Our method has the unique design of exploiting strong supervision, i...
December 8, 2016: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/27956021/prediction-of-the-drilling-path-to-surgically-pin-the-femoral-neck-from-the-spatial-location-of-pelvic-and-femoral-anatomical-landmarks-a-cadaver-validation-study
#14
V Sholukha, J Panda, P Salvia, B Beyer, M Rooze, S Van Sint Jan
Several clinical applications rely on accurate guiding information when drilling along the femoral neck (e.g., pin insertion in case of neck fracture). Currently, applications rely on real-time X-ray imaging, which results in irradiation issues for the surgeon conducting the operation. The goal of this paper was to develop an X-ray-free method that would allow for a pathway to be drilled between the lateral aspect of the femoral diaphysis (the so-called piercing point), the femoral neck and the head centres...
December 9, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27943173/discounting-the-recommendations-of-the-second-panel-on-cost-effectiveness-in-health-and-medicine
#15
Mike Paulden, James F O'Mahony, Christopher McCabe
Twenty years ago, the "Panel on Cost-effectiveness in Health and Medicine" published a landmark text setting out appropriate methods for conducting cost-effectiveness analyses of health technologies. In the two decades since, the methods used for economic evaluations have advanced substantially. Recently, a "second panel" (hereafter "the panel") was convened to update the text and its recommendations were published in November 2016. The purpose of this paper is to critique the panel's updated guidance regarding the discounting of costs and health effects...
January 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/27913349/adaptive-cascade-regression-model-for-robust-face-alignment
#16
Qingshan Liu, Jiankang Deng, Jing Yang, Guangcan Liu, Dacheng Tao
Cascade regression is a popular face alignment approach, and it has achieved good performances on the wild databases. However, it depends heavily on local features in estimating reliable landmark locations and therefore suffers from corrupted images, such as images with occlusion, which often exists in real-world face images. In this paper, we present a new adaptive cascade regression model for robust face alignment. In each iteration, the shape-indexed appearance is introduced to estimate the occlusion level of each landmark, and each landmark is then weighted according to its estimated occlusion level...
December 1, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27908160/correspondence-optimization-in-2d-standardized-carotid-wall-thickness-map-by-description-length-minimization-a-tool-for-increasing-reproducibility-of-3d-ultrasound-based-measurements
#17
Yimin Chen, Bernard Chiu
PURPOSE: The previously described 2D standardized vessel-wall-plus-plaque thickness (VWT) maps constructed from 3D ultrasound vessel wall measurements using an arc-length (AL) scaling approach adjusted the geometric variability of carotid arteries and has allowed for the comparisons of VWT distributions in longitudinal and cross-sectional studies. However, this mapping technique did not optimize point correspondence of the carotid arteries investigated. The potential misalignment may lead to errors in point-wise VWT comparisons...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27900308/chronic-knee-extensor-mechanism-lesions-in-total-knee-arthroplasty-a-literature-review
#18
Umberto Cottino, Davide Deledda, Federica Rosso, Davide Blonna, Davide Edoardo Bonasia, Roberto Rossi
Knee extensor mechanism rupture is a serious complication of total knee arthroplasty (TKA). Its prevalence ranges from 1 to 10% and it is commonly observed as a chronic multifactorial pathology with the patellar tendon as the most common site of rupture. Knee extensor mechanism reconstruction can be performed using allogenic or synthetic grafts. In the literature it is still not clear whether one of these techniques is superior to the other and the choice is usually tailored to the patient case by case. Allografts allow better restoration of the anatomical landmarks, whereas the mesh technique is more reproducible and the graft does not elongate over time...
July 2016: Joints
https://www.readbyqxmd.com/read/27893304/blame-it-on-southern-but-it-s-a-western-blot
#19
Daniel J Klionsky
Edwin M. Southern is a professor emeritus at the University of Oxford. He is perhaps best known for development of the "Southern blot" (Dr. Southern was at the University of Edinburgh when he wrote his landmark paper). The Southern blot provided a scientific breakthrough by allowing scientists to detect a particular DNA sequence without first purifying it from the rest of the genome; the basic method involves the transfer of the DNA to a membrane, followed by detection with a specific probe. Although few people perform Southern blots as originally carried out by Southern, due in part to the more recent technique of the polymerase chain reaction, the basic concept continues to play an important role in molecular biology...
January 2, 2017: Autophagy
https://www.readbyqxmd.com/read/27891032/clinical-anatomy-and-significance-of-the-thoracic-intervertebral-foramen-a-cadaveric-study-and-review-of-the-literature
#20
Grigorios Gkasdaris, Grigorios Tripsianis, Konstantinos Kotopoulos, Stylianos Kapetanakis
INTRODUCTION: The literature is lacking information on the anatomy and the osseous dimensions of the thoracic intervertebral foramen (IVF). We describe the anatomy of the broader area, and we proceed with morphometric data of the vertebrae and the foramina. Depiction of these features is provided with imaging and illustrations. The purpose of this paper is to survey and present the anatomy of the foramen as a whole and provide baseline statistical data. MATERIALS AND METHODS: We review relevant literature, and we present data obtained from skeletal samples of known population and sex...
October 2016: Journal of Craniovertebral Junction and Spine
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