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https://www.readbyqxmd.com/read/28722085/-anatomical-planes-and-landmarks-of-transanal-total-mesorectal-excision-for-rectal-cancer-and-prophylaxis-of-intraoperative-complications
#1
Zhanlong Shen, Yingjiang Ye, Shan Wang
Total mesorectal excision (TME) is a mile-stone procedure in the history of rectal cancer surgery, but the exposure of surgical field of distal rectum is usually poor in patients with male, obese and narrow pelvis, which may lead to tumor residue and relative complications. Recently, a new technique called transanal TME (taTME) is considered to solve the above problems, but most medical centers are still in the learning curve of this procedure. Therefore, anatomical planes and landmarks of taTME for rectal cancer and prophylaxis of intraoperative complications are induced in this paper, which includes posterior plane: angle of anus and distal mesorectum and bleeding of mesorectum; rectosacral fascia and presacral bleeding; lateral and posterior-lateral plane: posterior branches of pelvic plexus and damage of anal function; anterior plane: vessel branches of neurovascular bundle and bleeding...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28712912/multixplore-visual-exploration-platform-for-multimodal-neuroimaging-data
#2
Saeed M Bakhshmand, Ali R Khan, Sandrine de Ribaupierre, Roy Eagleson
BACKGROUND: Construction of brain functional and structural networks by neuroimaging methods facilitates inter-modal studies. These type of studies often demand exploration tools to carry out functional-structural discoveries and answer questions regarding the anatomical basis of brain networks. NEW METHOD: This paper describes the design and development of a software module for interactive visualization and exploration of dual-modal brain networks. Our objective was to equip the user with a research tool to investigate brain connectivity matrices while visualizing relevant anatomical landmarks within a 3D volumetric view...
July 13, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28705077/fifty-years-of-hemodialysis-access-literature-the-fifty-most-cited-publications-in-the-medical-literature
#3
Edvard Skripochnik, David J O'Connor, Eric B Trestman, Evan C Lipsitz, Larry A Scher
Objectives The modern era of hemodialysis access surgery began with the publication in 1966 by Brescia et al. describing the use of a surgically created arteriovenous fistula. Since then, the number of patients on chronic hemodialysis and the number of publications dealing with hemodialysis access have steadily increased. We have chronicled the increase in publications in the medical literature dealing with hemodialysis access by evaluating the characteristics of the 50 most cited articles. Methods We queried the Science Citation Index from the years 1960-2014...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28699568/evaluation-of-the-informatician-perspective-determining-types-of-research-papers-preferred-by-clinicians
#4
Boshu Ru, Xiaoyan Wang, Lixia Yao
BACKGROUND: To deliver evidence-based medicine, clinicians often reference resources that are useful to their respective medical practices. Owing to their busy schedules, however, clinicians typically find it challenging to locate these relevant resources out of the rapidly growing number of journals and articles currently being published. The literature-recommender system may provide a possible solution to this issue if the individual needs of clinicians can be identified and applied...
July 5, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28699246/a-potential-pitfall-in-studies-of-biological-shape-does-size-matter
#5
David Outomuro, Frank Johansson
The number of published studies using geometric morphometrics (GM) for analysing biological shape has increased steadily since the beginning of the 1990's, covering multiple research areas such as ecology, evolution, development, taxonomy and palaeontology. Unfortunately, we have observed that many published studies using GM do not evaluate the potential allometric effects of size on shape, which normally require consideration or assessment. This might lead to misinterpretations and flawed conclusions in certain cases, especially when size effects explain a large part of the shape variation...
July 12, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28698936/creation-of-an-aesthetic-male-nipple-areolar-complex-in-female-to-male-transgender-chest-reconstruction
#6
Cori A Agarwal, Vanessa T Wall, Sagar T Mehta, Daniel P Donato, Norelle K Walzer
BACKGROUND: Female-to-male chest wall reconstruction is becoming more common, but while there is a growing body of the literature describing technique and algorithms, little detail is written on methods for creating a male appearing nipple areolar complex (NAC) from a female NAC utilizing free nipple graft techniques. Incorrect positioning of the NAC on the chest wall and suboptimal shaping and sizing of the NAC are common pitfalls in male NAC creation. METHODS: With this paper, we present techniques for nipple grafting to achieve improved male appearing NACs, as well as a simple, reproducible method for appropriate placement of the NAC relative to the borders of the pectoralis muscle...
July 11, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28694770/spatial-cues-provided-by-sound-improve-postural-stabilization-evidence-of-a-spatial-auditory-map
#7
Lennie Gandemer, Gaetan Parseihian, Richard Kronland-Martinet, Christophe Bourdin
It has long been suggested that sound plays a role in the postural control process. Few studies however have explored sound and posture interactions. The present paper focuses on the specific impact of audition on posture, seeking to determine the attributes of sound that may be useful for postural purposes. We investigated the postural sway of young, healthy blindfolded subjects in two experiments involving different static auditory environments. In the first experiment, we compared effect on sway in a simple environment built from three static sound sources in two different rooms: a normal vs...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28693677/directed-panspermia-a-21st-century-perspective
#8
Roy D Sleator, Niall Smith
Applying 21st century technology to the design and development of a hypothetical extra-terrestrial colonisation programme, we reimagine 'directed panspermia' from the perspective of Crick and Orgel's 'technological society', 44 years after the publication of their original landmark paper.
May 1, 2017: Science Progress
https://www.readbyqxmd.com/read/28693008/two-landmark-studies-published-in-1976-1977-paved-the-way-for-the-recognition-of-human-papillomavirus-as-the-major-cause-of-the-global-cancer-burden
#9
Kari J Syrjänen
Two groundbreaking reports were published in Acta Cytologica at the transition of 1976 to 1977. One appeared in the last issue of 1976 [Meisels and Fortin: Acta Cytol 1976;20:505-509] and the other in the first issue of 1977 [Purola and Savia: Acta Cytol 1977;21:26-31]. Today, 40 years later, it is not an overstatement to conclude that these are the two most influential studies ever published in this journal. Two reports with a similar content being published so close together (in the same journal) raised the question "Which of the two reports was truly submitted first?" In this commentary, this enigma is clarified beyond reasonable doubt, based on the well-considered testimonial of Prof...
July 11, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28690834/from-disease-modelling-to-personalised-therapy-in-patients-with-cep290-mutations
#10
Elisa Molinari, Shalabh Srivastava, John A Sayer, Simon A Ramsbottom
Mutations that give rise to premature termination codons are a common cause of inherited genetic diseases. When transcripts containing these changes are generated, they are usually rapidly removed by the cell through the process of nonsense-mediated decay. Here we discuss observed changes in transcripts of the centrosomal protein CEP290 resulting not from degradation, but from changes in exon usage. We also comment on a landmark paper (Drivas et al. Sci Transl Med. 2015) where modelling this process of exon usage may be used to predict disease severity in CEP290 ciliopathies, and how understanding this process may potentially be used for therapeutic benefit in the future...
2017: F1000Research
https://www.readbyqxmd.com/read/28651099/brain-shift-compensation-using-intraoperative-ultrasound-and-constraint-based-biomechanical-simulation
#11
Fanny Morin, Hadrien Courtecuisse, Ingerid Reinertsen, Florian Le Lann, Olivier Palombi, Yohan Payan, Matthieu Chabanas
PURPOSE: During brain tumor surgery, planning and guidance are based on preoperative images which do not account for brain-shift. However, this deformation is a major source of error in image-guided neurosurgery and affects the accuracy of the procedure. In this paper, we present a constraint-based biomechanical simulation method to compensate for craniotomy-induced brain-shift that integrates the deformations of the blood vessels and cortical surface, using a single intraoperative ultrasound acquisition...
June 15, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28644815/landmark-image-retrieval-by-jointing-feature-refinement-and-multimodal-classifier-learning
#12
Xiaoming Zhang, Senzhang Wang, Zhoujun Li, Shuai Ma
Landmark retrieval is to return a set of images with their landmarks similar to those of the query images. Existing studies on landmark retrieval focus on exploiting the geometries of landmarks for visual similarity matches. However, the visual content of social images is of large diversity in many landmarks, and also some images share common patterns over different landmarks. On the other side, it has been observed that social images usually contain multimodal contents, i.e., visual content and text tags, and each landmark has the unique characteristic of both visual content and text content...
June 20, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28637104/-treatment-options-in-non-alcoholic-fatty-liver-disease
#13
REVIEW
Won Kim
The prevalence of non-alcoholic fatty liver disease (NAFLD) has sharply increased over the past several decades in Korea. In most cases of NAFLD, metabolic stress and cellular apoptosis are often driven by metabolic abnormality, eventually leading to inflammation and fibrosis . Along with a dramatic surge in the obesity epidemic, 10-20% of NAFLD patients ultimately progress to non-alcoholic steatohepatitis (NASH), a precursor to cirrhosis and hepatocellular carcinoma, as well as multi-organ systemic diseases...
June 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28634701/the-50-most-cited-articles-in-facial-plastic-surgery
#14
Michael T Chang, Zachary G Schwam, Christopher A Schutt, Emily M Kamen, Boris Paskhover
Bibliometric analysis is a common method to determine the most influential articles in medical specialties, as it is an objective measure of peer recognition of scientific work. This study is the first bibliometric analysis of the literature in facial plastic surgery, to determine the most cited papers in the field. Bibliometric analysis was performed using the Science Citation Index from the Institute for Scientific Information, accessed through the Web of Science™. Filter terms relevant to the field of facial plastic surgery were used to identify the 50 most cited journal articles between 1900 and 2016...
June 20, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28629191/a-new-filtering-and-smoothing-algorithm-for-railway-track-surveying-based-on-landmark-and-imu-odometer
#15
Qingan Jiang, Wenqi Wu, Mingming Jiang, Yun Li
High-accuracy railway track surveying is essential for railway construction and maintenance. The traditional approaches based on total station equipment are not efficient enough since high precision surveying frequently needs static measurements. This paper proposes a new filtering and smoothing algorithm based on the IMU/odometer and landmarks integration for the railway track surveying. In order to overcome the difficulty of estimating too many error parameters with too few landmark observations, a new model with completely observable error states is established by combining error terms of the system...
June 19, 2017: Sensors
https://www.readbyqxmd.com/read/28626470/multi-infarct-dementia-a-historical-perspective
#16
REVIEW
Erin McKay, Scott E Counts
BACKGROUND: Multi-infarct dementia (MID), a prominent subtype of vascular dementia (VaD), has only achieved recognition in the last 4 decades. Since its original description, the characterization, etiological understanding, and therapeutic direction of MID and other VaD subtypes has progressed at an astounding rate. SUMMARY: This paper divides the landmark discoveries and emergence of new research strategies for MID into decade-defining patterns so that a condensed picture of the total history of MID and its eventual inclusion as a VaD subtype emerges...
January 2017: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/28620458/reproducibility2020-progress-and-priorities
#17
REVIEW
Leonard P Freedman, Gautham Venugopalan, Rosann Wisman
The preclinical research process is a cycle of idea generation, experimentation, and reporting of results. The biomedical research community relies on the reproducibility of published discoveries to create new lines of research and to translate research findings into therapeutic applications. Since 2012, when scientists from Amgen reported that they were able to reproduce only 6 of 53 "landmark" preclinical studies, the biomedical research community began discussing the scale of the reproducibility problem and developing initiatives to address critical challenges...
2017: F1000Research
https://www.readbyqxmd.com/read/28609480/an-automated-and-reliable-method-for-breath-detection-during-variable-mask-pressures-in-awake-and-sleeping-humans
#18
Chinh D Nguyen, Jason Amatoury, Jayne C Carberry, Danny J Eckert
Accurate breath detection is crucial in sleep and respiratory physiology research and in several clinical settings. However, this process is technically challenging due to measurement and physiological artifacts and other factors such as variable leaks in the breathing circuit. Recently developed techniques to quantify the multiple causes of obstructive sleep apnea, require intermittent changes in airway pressure applied to a breathing mask. This presents an additional unique challenge for breath detection...
2017: PloS One
https://www.readbyqxmd.com/read/28598743/implementing-competency-based-medical-education-moving-forward
#19
Jason R Frank, Linda Snell, Robert Englander, Eric S Holmboe
For more than 60 years, competency-based education has been proposed as an approach to education in many disciplines. In medical education, interest in CBME has grown dramatically in the last decade. This editorial introduces a series of papers that resulted from summits held in 2013 and 2016 by the International CBME Collaborators, a scholarly network whose members are interested in developing competency-based approaches to preparing the next generation of health professionals. An overview of the papers is given, as well as a summary of landmarks in the conceptual evolution and implementation of CBME...
June 2017: Medical Teacher
https://www.readbyqxmd.com/read/28595892/localization-of-optic-disc-and-fovea-in-retinal-images-using-intensity-based-line-scanning-analysis
#20
Ravi Kamble, Manesh Kokare, Girish Deshmukh, Fawnizu Azmadi Hussin, Fabrice Mériaudeau
Accurate detection of diabetic retinopathy (DR) mainly depends on identification of retinal landmarks such as optic disc and fovea. Present methods suffer from challenges like less accuracy and high computational complexity. To address this issue, this paper presents a novel approach for fast and accurate localization of optic disc (OD) and fovea using one-dimensional scanned intensity profile analysis. The proposed method utilizes both time and frequency domain information effectively for localization of OD...
April 27, 2017: Computers in Biology and Medicine
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