keyword
MENU ▼
Read by QxMD icon Read
search

Vestibular schwannoma

keyword
https://www.readbyqxmd.com/read/28323186/micro-multileaf-collimator-linac-radiosurgery-for-vestibular-schwannomas
#1
Essam M Rezk, Faycal El Majdoub, Martin Kocher, Harald Treuer, Volker Sturm, Mohammad Maarouf
OBJECTIVE: This study evaluates the efficacy of linear accelerator (LINAC) radiosurgery using micro multi-leaf collimator technique (μMLC) in the treatment of a consecutive series of patients with vestibular schwannomas. PATIENTS AND METHODS: In this retrospective study, we enrolled 50 patients with non-neurofibromatosis type 2 vestibular schwannoma who were treated with μMLC LINAC-based SRS at University Hospital of Cologne, Germany. A minimum clinical follow-up of 24 months was conducted...
March 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28321373/a-review-of-skull-base-tumor-clinical-trials-past-trends-and-future-opportunities
#2
Anand Devaiah, Charles Murchison
Objective Tumors of the anterior and lateral skull base (TALSB) are relatively rare but can be devastating to patients. By examining trials focused on TALSB, we can characterize the studies that predominate and better understand current directions of study. This gives us a better understanding of future studies to pursue. Study Design This is a retrospective analysis. Settings We set skull base tumor clinical trials in the United States which are listed in ClinicalTrials.gov. Subjects and Methods We used the information available on ClinicalTrials...
April 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28319458/quality-of-life-in-807-patients-with-vestibular-schwannoma-comparing-treatment-modalities
#3
Géke Soulier, Bibian M van Leeuwen, Hein Putter, Jeroen C Jansen, Martijn J A Malessy, Peter Paul G van Benthem, Andel G L van der Mey, Anne M Stiggelbout
Objective In vestibular schwannoma treatment, the choice among treatment modalities is controversial. The first aim of this study was to examine the quality of life of patients with vestibular schwannoma having undergone observation, radiation therapy, or microsurgical resection. The second aim was to examine the relationship between perceived symptoms and quality of life. Last, the association between quality of life and time since treatment was studied. Study Design Cross-sectional study. Setting Tertiary referral center...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28298021/prophylactic-nimodipine-treatment-and-improvement-in-hearing-outcome-after-vestibular-schwannoma-surgery-a-combined-analysis-of-a-randomized-multicenter-phase-iii-trial-and-its-pilot-study
#4
Christian Scheller, Andreas Wienke, Marcos Tatagiba, Alireza Gharabaghi, Kristofer F Ramina, Oliver Ganslandt, Barbara Bischoff, Johannes Zenk, Tobias Engelhorn, Cordula Matthies, Thomas Westermaier, Gregor Antoniadis, Maria Teresa Pedro, Veit Rohde, Kajetan von Eckardstein, Thomas Kretschmer, Malte Kornhuber, Jörg Steighardt, Michael Richter, Fred G Barker, Christian Strauss
OBJECT In clinical routines, neuroprotective strategies in neurosurgical interventions are still missing. A pilot study (n = 30) and an analogously performed Phase III trial (n = 112) pointed to a beneficial effect of prophylactic nimodipine and hydroxyethyl starch (HES) in vestibular schwannoma (VS) surgery. Considering the small sample size, the data from both studies were pooled. METHODS The patients in both investigator-initiated studies were assigned to 2 groups. The treatment group (n = 70) received parenteral nimodipine (1-2 mg/hour) and HES (hematocrit 30%-35%) from the day before surgery until the 7th postoperative day...
February 24, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28295370/the-human-endolymphatic-sac-expresses-natriuretic-peptides
#5
Martin Nue Møller, Svend Kirkeby, Jonas Vikeså, Finn Cilius Nielsen, Per Cayé-Thomasen
OBJECTIVES/HYPOTHESIS: The function of the human endolymphatic sac (ES) has been enigmatic for decades. Hypotheses include controlling endolymphatic fluid homeostasis and inner ear immunological defense. Additionally, several studies indicate a possible endocrine capacity and a yet undefined role in intracranial pressure homeostasis. However, no direct evidence of such capacity exists. This study aims to explore and identify the hypothesized endocrine capacity of the human ES. STUDY DESIGN: DNA microarrays and immunohistochemistry were used for analyses of fresh human ES tissue samples...
March 14, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28295212/constitutional-lztr1-mutation-presenting-with-a-unilateral-vestibular-schwannoma-in-a-teenager
#6
Karen W Gripp, Laura Baker, Vinay Kandula, Joseph Piatt, Andrew Walter, Zhenbin Chen, Ludwine Messiaen
Schwannomatosis is a rare neurofibromatosis clinically diagnosed by age-dependent criteria, with bilateral vestibular schwannoma and/or a constitutional NF2 mutation representing exclusion criteria. Following SMARCB1 germline mutations, constitutional mutations in LZTR1 were discovered. We report on the molecular investigation in a patient presenting at 14 years with a unilateral vestibular schwannoma, ultimately causing blindness and unilateral hearing loss, in the absence of other schwannomas or a positive family history...
March 14, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28294345/long-term-mri-surveillance-after-microsurgery-for-vestibular-schwannoma
#7
Mia E Miller, Harrison Lin, Bill Mastrodimos, Roberto A Cueva
OBJECTIVES: To determine the optimal postoperative magnetic resonance imaging (MRI) schedule and length of follow-up for patients undergoing microsurgical excision of vestibular schwannoma (VS). STUDY DESIGN: A retrospective review of patients who underwent microsurgical excision of VS at a single tertiary care center between January 1993 and March 2004. METHODS: Two hundred and twenty subjects were analyzed and characteristics gathered, including tumor size, surgical approach, completeness of resection, and length of follow-up to last MRI...
March 14, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28293782/baha-implant-as-a-hearing-solution-for-single-sided-deafness-after-retrosigmoid-approach-for-the-vestibular-schwannoma-surgical-results
#8
Jan Boucek, Jan Vokral, Libor Cerny, Martin Chovanec, Jiří Skrivan, Eduard Zverina, Jan Betka, Michal Zabrodsky
Skull base tumors and, in particular, vestibular schwannoma (VS) are among the etiological reasons for single-sided deafness (SSD). Patients with SSD have problems in understanding speech in a noisy environment and cannot localize the direction of sounds. Baha is one of the most frequently used systems for SSD compensation. Out of 38 patients with SSD after retrosigmoid removal of VS who underwent testing with Baha softband, 16 were satisfied and were indicated for Baha implantation. Two surgical approaches have been used-the Nijmegen linear incision technique with subdermal thinning (Group I, implant BI300) and fast surgery technique without subdermal thinning (Group II, implant BIA400)...
March 14, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28284969/factors-leading-to-oro-facial-herpetic-eruptions-in-patients-undergoing-surgery-for-vestibular-schwannoma
#9
Satya Deo Pandey, Anant Mehrotra, Kuntal Kanti Das, Kamlesh Singh Bhaisora, Jayesh Sardhara, Pradeep Sharma, Suyash Singh, Arun Kumar Srivastava, Rabi Narayan Sahu, Awadesh Kumar Jaiswal, Sanjay Behari, Raj Kumar
No abstract text is available yet for this article.
March 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28284966/the-impact-of-primary-treatment-strategy-on-vestibular-schwannoma-patient-quality-of-life
#10
Robert W Foley, Robert M Maweni, Hussein Jaafar, Rory McConn Walsh, Mohsen Javadpour, Daniel Rawluk
OBJECTIVE: To assess the quality of life (QoL) in a representative sample of vestibular schwannoma patients and to ascertain the differences in outcomes associated with distinct management strategies. PATIENTS & METHODS: Vestibular Schwannoma patients attending a tertiary referral centre were asked to complete the FACT-Br Questionnaire, which assesses QoL in five domains: physical, social, emotional and functional and a brain cancer specific domain. Results were analysed in the overall cohort and in surgery, stereotactic radiosurgery and conservative management subgroups...
March 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28283837/vascular-hyperpermeability-as-a-hallmark-of-phacomatoses-is-the-etiology-angiogenesis-related-to-or-comparable-with-mechanisms-seen-in-inflammatory-pathways-part-ii-angiogenesis-and-inflammation-related-molecular-pathways-tumor-associated-macrophages-and-possible
#11
REVIEW
Yosef Laviv, Burkhard Kasper, Ekkehard M Kasper
Phacomatoses are a special group of familial hamartomatous syndromes with unique neurocutaneous manifestations as well as characteristic tumors. Neurofibromatosis type 2 (NF2) and tuberous sclerosis complex (TSC) are representatives of this family. A vestibular schwannoma (VS) and subependymal giant cell tumor (SGCT) are two of the most common intracranial tumors associated with these syndromes, related to NF2 and TSC, respectively. These tumors can present with an obstructive hydrocephalus due to their location adjacent to or in the ventricles...
March 11, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28282143/proteome-analysis-of-human-perilymph-using-an-intraoperative-sampling-method
#12
Heike Andrea Schmitt, Andreas Pich, Anke Schröder, Verena Scheper, Giorgio Lilli, Günter Reuter, Thomas Lenarz
The knowledge about the etiology and pathophysiology of sensorineural hearing loss (SNHL) is still very limited. The project aims at the improvement of understanding different types of SNHL by proteome analysis of human perilymph. Sampling of perilymph has been established during inner ear surgeries (cochlear implant and vestibular schwannoma surgeries) and safety of the sampling method was determined by pure tone audiometry. An in-depth shot-gun proteomics approach was performed to identify cochlear proteins and individual proteome in perilymph of patients...
March 10, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28271520/expanded-transcanal-transpromontorial-approach-to-the-internal-auditory-canal-pilot-clinical-experience
#13
Livio Presutti, Matteo Alicandri-Ciufelli, Marco Bonali, Alessia Rubini, Giacomo Pavesi, Alberto Feletti, Barbara Masotto, Lukas Anschuetz, Daniele Marchioni
OBJECTIVES/HYPOTHESIS: The aim of this study was to describe and evaluate the feasibility of an expanded transcanal transpromontorial approach, developed from the exclusive endoscopic transcanal transpromontorial approach. STUDY DESIGN: Retrospective case series. METHODS: Retrospective chart review of 10 patients operated by an expanded transcanal transpromontorial approach in two tertiary referral centers (University Hospital of Modena, Italy and University Hospital of Verona, Italy)...
March 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28271169/-intraoperative-monitoring-of-the-facial-nerve-vestibular-schwannoma-surgery
#14
J Prell, C Strauss, S K Plontke, S Rampp
BACKGROUND: In vestibular schwannoma surgery, facial nerve injury with consecutive functional impairment is one of the most important complications. Intraoperative monitoring of facial nerve function has been developed in order to avoid this complication. OBJECTIVE: Which methods for intraoperative monitoring have been developed? Which methods are in use today and what can they achieve in modern vestibular schwannoma surgery? MATERIAL AND METHODS: This article provides an evaluation and summary of the literature, as well as a discussion of the methods and their ability to achieve the goals of intraoperative monitoring...
March 7, 2017: HNO
https://www.readbyqxmd.com/read/28265819/vascular-hyperpermeability-as-a-hallmark-of-phacomatoses-is-the-etiology-angiogenesis-comparable-with-mechanisms-seen-in-inflammatory-pathways-part-i-historical-observations-and-clinical-perspectives-on-the-etiology-of-increased-csf-protein-levels-csf-clotting
#15
REVIEW
Yosef Laviv, Burkhard S Kasper, Ekkehard M Kasper
Phacomatoses are a special group of familial hamartomatous syndromes with unique neuro-cutaneous manifestations as well as disease characteristic tumors. Neurofibromatosis 2 (NF2) and tuberous sclerosis complex (TSC) are representatives of this family. Vestibular schwannoma (VS) and subependymal giant cell tumor (SGCT) are two of the most common intracranial tumors associated with NF2 and TSC, respectively. These tumors can present with obstructive hydrocephalus due to their location adjacent to or in the ventricles...
March 7, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28248607/multivariate-analysis-of-factors-influencing-facial-nerve-outcome-following-microsurgical-resection-of-vestibular-schwannoma
#16
Renato Torres, Yann Nguyen, Antoine Vanier, Mustapha Smail, Evelyne Ferrary, Olivier Sterkers, Michel Kalamarides, Daniele Bernardeschi
Objective To assess through multivariate analysis the clinical pre- and intraoperative factors of facial nerve outcomes at day 8 and 1-year recovery of facial palsy, as compared with day 8 status among patients who underwent total resection of unilateral vestibular schwannoma. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods This study included 229 patients with preoperative normal facial function and anatomic preservation of the facial nerve. Clinical, radiologic, and intraoperative factors were assessed according to facial nerve function at day 8 and 1 year...
March 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28224282/micrornas-effective-elements-in-ear-related-diseases-and-hearing-loss
#17
REVIEW
Mohammad-Reza Mahmoudian-Sani, Ameneh Mehri-Ghahfarrokhi, Fereshteh Ahmadinejad, Morteza Hashemzadeh-Chaleshtori, Massoud Saidijam, Mohammad-Saeid Jami
miRNAs are important factors for post-transcriptional process that controls gene expression at mRNA level. Various biological processes, including growth and differentiation, are regulated by miRNAs. miRNAs have been demonstrated to play an essential role in development and progression of hearing loss. Nowadays, miRNAs are known as critical factors involved in different physiological, biological, and pathological processes, such as gene expression, progressive sensorineural hearing loss, age-related hearing loss, noise-induced hearing loss, cholesteatoma, schwannomas, and inner ear inflammation...
February 21, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28223251/facial-nerve-function-and-quality-of-resection-in-large-and-giant-vestibular-schwannomas-surgery-operated-by-retrosigmoid-transmeatal-approach-in-semisetting-position-with-intraoperative-facial-nerve-monitoring
#18
Lotfi Boublata, Mohamad Belahreche, Rafik Ouchtati, Zarinah Shabay, Lila Boutiah, Mohamad Kabache, Nadji M'Hamed, Zoheir Djenna, Hocine Bounecer, Nafa Ioualalen
No abstract text is available yet for this article.
February 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28219164/-a-combination-use-of-endoscope-and-microscope-in-cerebral-pontine-angle-surgery
#19
Z Y Wang, H Jia, J Yang, H Y Tan, H Wu
Objective: To evaluate the application of combination use of microscope and endoscope in cerebral pontine angle (CPA) surgery. Methods: A total of 72 patients undergone lateral skull base surgeries via endoscope under microscopic control from January 2006 to January 2015 was reviewed respectively. The patients including 35 males and 37 females were composed of 22 cases of vestibular swannnomas, 45 cases of cranial neuropathy and 5 cases of CPA chelesteatoma. Twenty cases of vestibular swannnomas, 15 cases of cranial neuropathy and 2 cases of CPA chelesteatoma undergone the surgery via retrosigmoid approach, while other cases undergone the surgery via retrolabyrinthine approach...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28218014/bilateral-otoneurological-pathology-to-operate-or-not
#20
Shivun Khosla, Matthew Elliot, Neil Donnelly
OBJECTIVE: To illustrate our experience when managing a complex patient with potentially life-threatening bilateral otological disease facing multisensory compromise including complete loss of audiovestibular function and visual disturbance Clinical presentation: A 67 year old lady, presented with a large left vestibular schwannoma and extensive right cholesteatoma encircling the otic capsule. She underwent translabyrinthine resection of the vestibular schwannoma, resulting in profound sensorineural hearing loss, vestibular hypofunction and corneal scarring following an initial temporary facial palsy...
March 2017: Cochlear Implants International
keyword
keyword
10618
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"