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https://www.readbyqxmd.com/read/28428673/migrant-general-practitioners-experiences-of-using-interpreters-in-health-care-a-qualitative-explorative-study
#1
Ferid Krupic, Kristian Samuelsson, Nabi Fatahi, Olof Skoldenberg, Arkan S Sayed-Noor
BACKGROUND: According to the UNHCR, 250 million people currently live outside their country of birth. The growing multicultural population poses a major challenge to healthcare professionals who aim to provide individualized, holistic care, which respects the individual's autonomy. To ensure basic rights, healthcare interventions should be guided by the value of benefiting others; individuals should be treated honestly, equally, and impartially. OBJECTIVE: To investigate immigrant doctors' experiences of using interpreters in the Swedish health-care system...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28425021/is-the-autism-spectrum-quotient-a-valid-measure-of-traits-associated-with-the-autism-spectrum-a-rasch-validation-in-adults-with-and-without-autism-spectrum-disorders
#2
Lars-Olov Lundqvist, Helen Lindner
The Autism-Spectrum Quotient (AQ) is among the most widely used scales assessing autistic traits in the general population. However, some aspects of the AQ are questionable. To test its scale properties, the AQ was translated into Swedish, and data were collected from 349 adults, 130 with autism spectrum disorder (ASD) and 219 without ASD, and analysed with Rasch. Several scale properties of the AQ were satisfactory but it did not meet the criterion of a unidimensional measure of autistic traits. The Rasch analysis showed that the 50-item AQ could be reduced to a 12-item subset with little loss of explanatory power, with the potential to efficiently measure the degree to which adults with and without ASD show autistic traits...
April 19, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28424157/childhood-adversity-and-risk-of-suicide-cohort-study-of-548%C3%A2-721-adolescents-and-young-adults-in-sweden
#3
Charlotte Björkenstam, Kyriaki Kosidou, Emma Björkenstam
Objective To examine the relation between childhood adversity, the role of school performance, and childhood psychopathology and the risk of suicide.Design Cohort study of register based indicators of childhood adversity (at ages 0-14) including death in the family (suicide analysed separately), parental substance abuse, parental psychiatric disorder, substantial parental criminality, parental separation/single parent household, receipt of public assistance, and residential instability.Setting Swedish medical birth register and various Swedish population based registers...
April 19, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28423729/digitalis-use-and-risk-of-gastrointestinal-cancers-a-nationwide-population-based-cohort-study
#4
Shao-Hua Xie, Tomas Jernberg, Fredrik Mattsson, Jesper Lagergren
BACKGROUND: Gastrointestinal cancers are characterized by a male predominance, suggesting a role of sex hormones.We hypothesized that digitalis medication, due to its estrogenic properties, decreases the risk of male-predominated gastrointestinal cancers. RESULTS: Long -term digitalis use (≥2 years) was followed by decreased risk for several gastrointestinal cancers, but associations were statistically significant only for liver cancer (hazard ratio [HR]=0.40, 95% confidence interval (CI) 0...
March 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423398/treatment-restarting-after-discontinuation-of-adjuvant-hormone-therapy-in-breast-cancer-patients
#5
Wei He, Karin E Smedby, Fang Fang, Henrik Olsson, Sara Margolin, Per Hall, Kamila Czene
Background: Over half of breast cancer patients discontinue their adjuvant hormone therapy, permanently or temporarily. We aimed to identify predictors of treatment restarting after discontinuation of adjuvant hormone therapy and to test the hypothesis that treatment restarting is associated with better breast cancer outcomes. Methods: We conducted a population-based cohort study by linking data from the Stockholm-Gotland Breast Cancer Register, the Swedish Prescribed Drug Register, and a self-reported questionnaire...
October 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28419674/prognostic-risk-factors-of-first-recurrence-in-patients-with-primary-stage-i-ii-cutaneous-malignant-melanoma-from-the-population-based-swedish-melanoma-register
#6
J Lyth, M Falk, M Maroti, H Eriksson, C Ingvar
BACKGROUND: Prognostic factors in patients with localised primary cutaneous malignant melanoma (CMM) are well described. However, prognostic factors for recurrence are less documented. OBJECTIVES: The aim of this study was to identify prognostic risk factors for first recurrence in patients with localised stage I-II CMM using population-based data. METHODS: This study included 1 437 CMM patients registered in one region of Sweden during 1999-2012 followed-up through December 31, 2012...
April 17, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28419558/age-but-not-philadelphia-positivity-impairs-outcome-in-older-elderly-patients-with-acute-lymphoblastic-leukemia-in-sweden
#7
Piotr Kozlowski, Emma Lennmyr, Lucia Ahlberg, Per Bernell, Erik Hulegårdh, Holger Karbach, Karin Karlsson, Beata Tomaszewska-Toporska, Maria Åström, Heléne Hallböök
OBJECTIVES: Older/elderly patients with acute lymphoblastic leukemia (ALL) are poorly represented in clinical trials. METHODS: Using Swedish national leukemia registries, we investigated disease/patient characteristics, treatment choices, outcome, and the impact of an age-adapted protocol (introduced in 2009) in this population-based study of patients aged 55-85 years, diagnosed with ALL 2005-2012. RESULTS: Of 174 patients, 82% had B-phenotype, 11% Burkitt leukemia (excluded), and 7% T-phenotype...
April 18, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28418479/associations-of-maternal-antidepressant-use-during-the-first-trimester-of-pregnancy-with-preterm-birth-small-for-gestational-age-autism-spectrum-disorder-and-attention-deficit-hyperactivity-disorder-in-offspring
#8
Ayesha C Sujan, Martin E Rickert, A Sara Öberg, Patrick D Quinn, Sonia Hernández-Díaz, Catarina Almqvist, Paul Lichtenstein, Henrik Larsson, Brian M D'Onofrio
Importance: Prenatal antidepressant exposure has been associated with adverse outcomes. Previous studies, however, may not have adequately accounted for confounding. Objective: To evaluate alternative hypotheses for associations between first-trimester antidepressant exposure and birth and neurodevelopmental problems. Design, Setting, and Participants: This retrospective cohort study included Swedish offspring born between 1996 and 2012 and followed up through 2013 or censored by death or emigration...
April 18, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28417423/evaluation-of-the-expression-of-amyloid-precursor-protein-and-the-ratio-of-secreted-amyloid-beta-42-to-amyloid-beta-40-in-sh-sy5y-cells-stably-transfected-with-wild-type-single-mutant-and-double-mutant-forms-of-the-app-gene-for-the-study-of-alzheimer-s-disease
#9
Aslina Pahrudin Arrozi, Siti Nur Syazwani Shukri, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof, Mohd Hanafi Ahmad Damanhuri, Suzana Makpol
Neuroblastoma cell lines such as SH-SY5Y are the most frequently utilized models in neurodegenerative research, and their use has advanced the understanding of the pathology of neurodegeneration over the past few decades. In Alzheimer's disease (AD), several pathogenic mutations have been described, all of which cause elevated levels of pathological hallmarks such as amyloid-beta (Aβ). Although the genetics of Alzheimer's disease is well known, familial AD only accounts for a small number of cases in the population, with the rest being sporadic AD, which contains no known mutations...
April 17, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28416524/range-of-risk-factor-levels-control-mortality-and-cardiovascular-outcomes-in-type-1-diabetes-mellitus
#10
Aidin Rawshani, Araz Rawshani, Stefan Franzén, Björn Eliasson, Ann-Marie Svensson, Mervete Miftaraj, Darren K McGuire, Naveed Sattar, Annika Rosengren, Soffia Gudbjörnsdottir
BACKGROUND: Individuals with type 1 diabetes mellitus (T1DM) have a high risk of cardiovascular complications, but it is unknown to what extent fulfilling all cardiovascular treatment goals is associated with residual risk of mortality and cardiovascular outcomes in those with T1DM compared with the general population. METHODS: We included all patients ≥18 years of age with T1DM who were registered in the Swedish National Diabetes Register from January 1, 1998, through December 31, 2014, a total of 33 333 patients, each matched for age and sex with 5 controls without diabetes mellitus randomly selected from the population...
April 18, 2017: Circulation
https://www.readbyqxmd.com/read/28416350/survival-among-men-at-high-risk-of-disseminated-prostate-cancer-receiving-initial-locally-directed-radical-treatment-or-initial-androgen-deprivation-therapy
#11
Prasanna Sooriakumaran, Tommy Nyberg, Olof Akre, Anders Widmark, Freddie Hamdy, Markus Graefen, Stefan Carlsson, Gunnar Steineck, N Peter Wiklund
BACKGROUND: There is increasing low-quality evidence rationalizing the use of radical therapy for men at high risk of disseminated prostate cancer. OBJECTIVE: To investigate, using high-quality epidemiologic data, whether initial radical therapy in men at high risk of disseminated prostate cancer improves survival. DESIGN, SETTING, AND PARTICIPANTS: An observational population-based Swedish study from 1996 to 2010 of men at high risk of disseminated prostate cancer (prostate-specific antigen [PSA] >50) initially treated by radical therapy (radiation therapy [n=630] or radical prostatectomy [n=120]) or androgen deprivation therapy (n=17 602), and followed for up to 15 yr...
April 14, 2017: European Urology
https://www.readbyqxmd.com/read/28415966/birth-by-caesarean-section-and-school-performance-in-swedish-adolescents-a-population-based-study
#12
Eileen A Curran, Louise C Kenny, Christina Dalman, Patricia M Kearney, John F Cryan, Timothy G Dinan, Ali S Khashan
BACKGROUND: Our objective was to assess the impact of obstetric mode of delivery, and in particular birth by Caesarean section (CS), on school performance in adolescents using a large, population-based cohort. METHODS: We extracted data from the Swedish Medical Birth Register and National School Register. We included all live singleton births in Sweden from 1982-1995 (n = 1,489,925). School grades were reported on a scale from 0 to 320, scores less than 160 (i...
April 17, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28410353/post-colonoscopy-colorectal-cancers-in-sweden-room-for-quality-improvement
#13
Anna Forsberg, Ulf Hammar, Anders Ekbom, Rolf Hultcrantz
OBJECTIVE: Post-colonoscopy colorectal cancer (PCCRC), a cancer occurring within a short interval of a colonoscopy, might be partly explained as missed or incompletely resected lesions. Associated risk factors are age, sex, comorbidity, cancer location, and colonoscopy volume. There is a gap in the knowledge of prevalence of PCCRC and the impact of different risk factors in Sweden. METHODS: This is a retrospective population-based observational cohort study of the colonoscopies performed on adults during the years 2001-2010 that were identified from Swedish health registers...
April 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28407381/arrival-of-rabbit-haemorrhagic-disease-virus-2-to-northern-europe-emergence-and-outbreaks-in-wild-and-domestic-rabbits-oryctolagus-cuniculus-in-sweden
#14
A S Neimanis, H Ahola, S Zohari, U Larsson Pettersson, C Bröjer, L Capucci, D Gavier-Widén
Incursion of rabbit haemorrhagic disease virus (RHDV) into Sweden was documented in 1990 and it is now considered endemic in wild rabbit (Oryctolagus cuniculus) populations. Rabbit haemorrhagic disease virus 2 (RHDV2), a new, related lagovirus was first detected in France in 2010, and has spread rapidly throughout Europe and beyond. However, knowledge of RHDV2 in northern Europe is sporadic and incomplete, and in Sweden, routinely available diagnostic methods to detect rabbit haemorrhagic disease (RHD) do not distinguish between types of virus causing disease...
April 13, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28406579/disparities-in-pharmacotherapy-for-alcohol-use-disorder-in-the-context-of-universal-healthcare-a-swedish-register-study
#15
Katherine J Karriker-Jaffe, Jianguang Ji, Jan Sundquist, Kenneth S Kendler, Kristina Sundquist
BACKGROUND AND AIM: Pharmacotherapy can be an important part of the continuum of care for alcohol use disorder (AUD). The Swedish universal healthcare system emphasizes provision of care to marginalized groups. The primary aim was to test associations of neighbourhood deprivation and disadvantaged social status with receipt of AUD pharmacotherapy in this context. DESIGN: Data from linked population registers were used to follow an open cohort over 7 years. SETTING: Sweden...
April 12, 2017: Addiction
https://www.readbyqxmd.com/read/28404503/physical-mobility-physical-activity-and-obesity%C3%A2-among-elderly-findings-from-a-large-population-based-swedish-survey
#16
M Asp, B Simonsson, P Larm, A Molarius
OBJECTIVE: To examine how physical activity and physical mobility are related to obesity in the elderly. STUDY DESIGN: A cross-sectional study of 2558 men and women aged 65 years and older who participated in a population survey in 2012 was conducted in mid-Sweden with an overall response rate of 67%. METHODS: Obesity (body mass index ≥30 kg/m(2)) was based on self-reported weight and height, and physical activity and physical mobility on questionnaire data...
March 19, 2017: Public Health
https://www.readbyqxmd.com/read/28403041/sex-differences-in-time-trends-of-blood-pressure-among-swedish-septuagenarians-examined-three-decades-apart-a-longitudinal-population-study
#17
Erik Joas, Xinxin Guo, Silke Kern, Svante Östling, Ingmar Skoog
OBJECTIVE: The aim of this study was to analyze the influence of birth cohort, sex and age on the trajectories of SBP and DBP in two birth cohorts of 70-year-olds, examined 3 decades apart and followed up at ages 75 and 79-80 years. METHODS: Two population samples of 70-year-olds from Gothenburg, Sweden, were examined. The first, born in 1901-1902, was examined in 1971-1972 (n = 973). The second, born in 1930, was examined in 2000 (n = 509). Both samples were re-examined at ages 75 and 79-80 years...
April 11, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28402770/mortality-and-cardiovascular-disease-in-type-1-and-type-2-diabetes
#18
Aidin Rawshani, Araz Rawshani, Stefan Franzén, Björn Eliasson, Ann-Marie Svensson, Mervete Miftaraj, Darren K McGuire, Naveed Sattar, Annika Rosengren, Soffia Gudbjörnsdottir
Background Long-term trends in excess risk of death and cardiovascular outcomes have not been extensively studied in persons with type 1 diabetes or type 2 diabetes. Methods We included patients registered in the Swedish National Diabetes Register from 1998 through 2012 and followed them through 2014. Trends in deaths and cardiovascular events were estimated with Cox regression and standardized incidence rates. For each patient, controls who were matched for age, sex, and county were randomly selected from the general population...
April 13, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28402538/overall-and-abdominal-obesity-and-incident-aortic-valve-stenosis-two-prospective-cohort-studies
#19
Susanna C Larsson, Alicja Wolk, Niclas Håkansson, Magnus Bäck
Aims: The aim of this study was to examine the association of overall and abdominal obesity with aortic valve stenosis (AVS) incidence in two prospective cohorts. Methods and results: We used data from the Cohort of Swedish Men and the Swedish Mammography Cohort, involving 71 817 men and women who were free of cardiovascular disease and had reported their anthropometric measures in 1997. Aortic valve stenosis cases were ascertained through linkage with nationwide registers on hospitalization and causes of death...
April 11, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28402430/st-segment-depression-on-24-hour-electrocardiography-predicts-incident-atrial-fibrillation-in-two-population-based-cohorts
#20
Linda S B Johnson, John Berntsson, Tord Juhlin, Jeff S Healey, Steen Juul-Möller, Per Wollmer, Peter M Nilsson, Bo Hedblad, Mårten Rosenqvist, Gunnar Engström
Aims: ST-depression at 24hECG has not been studied in relation to atrial fibrillation (AF) risk. We aimed to determine whether ST-depression at 24hECG was associated with incident AF in two Swedish population-based cohorts - a sub-cohort of the Malmö Diet and Cancer study (MDCS), and the cohort 'Men born in 1914', and to determine whether 24hECG could be used to predict AF development. Methods and results: There were 378 acceptable 24hECG recordings in the MDCS (mean age 64...
April 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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