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https://www.readbyqxmd.com/read/28944619/comparative-study-of-new-autologous-material-bone-cartilage-composite-graft-bccg-for-ossiculoplasty-with-polycel-%C3%A2-and-titanium
#1
Ji Sun Kong, Chang Yeong Jeong, Myung Joo Shim, Woo Jin Kim, Sang Won Yeo, Shi Nae Park
OBJECTIVE: Ossiculoplasty is a surgical procedure that recreates sound transmission of the middle ear in conductive hearing loss. Various materials have been used for ossicular reconstruction, but the most ideal material for ossiculoplasty remains controversial. The purpose of this study is to introduce a novel method of autologous ossiculoplasty, bone-cartilage composite graft (BCCG), and to compare its surgical results with different types of ossiculoplastic prostheses. STUDY DESIGN: A retrospective study was performed in a tertiary referral center...
September 25, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28944603/the-effect-of-side-of-implantation-on-unilateral-cochlear-implant-performance-in-patients-with-prelingual-and-postlingual-sensorineural-hearing-loss-a-systematic-review
#2
Véronique J C Kraaijenga, Tyche C Derksen, Inge Stegeman, Adriana L Smit
OBJECTIVE: Cerebral lateralization of language processing leads to a right ear advantage in normal hearing subjects. The aim of this study was to present a systematic overview of the effect of implantation side on postoperative cochlear implant performance in patients with symmetrical severe to profound sensorineural hearing loss. DATA SOURCES: PubMed, Embase and The Cochrane Library databases. RESEARCH METHODS: Databases were searched from database inception up to January 9(th) 2017 for cochlear implant and side and all synonyms...
September 25, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28944379/septic-arthritis-of-the-temporomandibular-joint-after-acute-otitis-media-in-a-child
#3
Kathia Dubron, Jan Meeus, Koenraad Grisar, Stefanie Desmet, Titiaan Dormaar, Yannick Spaey, Constantinus Politis
Septic arthritis of the temporomandibular joint as a complication of acute otitis media is rare in the Western world. This report describes the case of a 7-year-old boy who had pain in his right ear and limited mouth opening, following the onset of acute otitis media. A contrast-enhanced computed tomography scan revealed right-sided mastoiditis and hydrops of the right temporomandibular joint, suggesting septic arthritis. Real-time PCR and microbiologic analysis identified Streptococcus pyogenes and Staphylococcus epidermidis in the joint aspirate...
September 22, 2017: Quintessence International
https://www.readbyqxmd.com/read/28944007/the-other-white-nose-syndrome-transcriptome-tolerant-and-susceptible-hosts-respond-differently-to-the-pathogen-pseudogymnoascus-destructans
#4
Christina M Davy, Michael E Donaldson, Craig K R Willis, Barry J Saville, Liam P McGuire, Heather Mayberry, Alana Wilcox, Gudrun Wibbelt, Vikram Misra, Trent Bollinger, Christopher J Kyle
Mitigation of emerging infectious diseases that threaten global biodiversity requires an understanding of critical host and pathogen responses to infection. For multihost pathogens where pathogen virulence or host susceptibility is variable, host-pathogen interactions in tolerant species may identify potential avenues for adaptive evolution in recently exposed, susceptible hosts. For example, the fungus Pseudogymnoascus destructans causes white-nose syndrome (WNS) in hibernating bats and is responsible for catastrophic declines in some species in North America, where it was recently introduced...
September 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28943207/supramolecular-nano-engineered-lipidic-carriers-based-on-diflunisal-phospholipid-complex-for-transdermal-delivery-qbd-based-optimization-characterization-and-preclinical-investigations-for-management-of-rheumatoid-arthritis
#5
Amanpreet Kaur, Bhupinder Singh Bhoop, Sanjay Chhibber, Gajanand Sharma, Vijay Singh Gondil, Om Prakash Katare
Diflunisal (DIF) is used for treatment of rheumatoid arthritis, osteoarthritis etc. DIF-phospholipid complex (DIF-PL complex) was prepared by solvent-evaporation method and characterized by molecular docking studies, SEM, FTIR, DSC, PXRD studies. Further, the DIF-PL complex was incorporated into supramolecular nano-engineered lipidic carriers (SNLCs) for transdermal delivery. The optimization exercise was done using Face centered cubic design (FCCD) after screening of variables by L8 Taguchi orthogonal array design...
September 21, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28943053/our-experience-with-500-patients-with-benign-paroxysmal-positional-vertigo-reexploring-aetiology-and-reevaluating-mri-investigation
#6
Fei Tan, Constantin Bartels, Rory McConn Walsh
OBJECTIVE: To explore the aetiology of and to evaluate the importance of MRI investigation on the posterior semicircular canal benign paroxysmal positional vertigo in an Irish population. METHODS: A retrospective observational study of 500 patients with posterior semicircular canal benign paroxysmal positional vertigo, diagnosed and treated by the senior author over a 10-year period. Most patients underwent an MRI brain and inner ear, following the same scan protocol...
September 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28942742/atlanto-axial-rotatory-fixation-a-serious-potential-complication-of-paediatric-ent-surgery-that-requires-prompt-diagnosis-and-treatment
#7
G James, D N P Thompson
BACKGROUND: Atlanto-axial rotatory fixation is a persistent deformity of the C1-2 vertebral relationship caused by subluxation of the articular surfaces, and can occur after positioning for ENT procedures where the head is rotated - for example to access the ear or posterior triangle of the neck. If promptly recognised, it can usually be managed successfully with conservative methods, without long-lasting sequelae, but delayed or inappropriate management may lead to permanent neck deformity, neurological problems and pain...
September 25, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28942630/effect-of-vowel-context-on-the-recognition-of-initial-consonants-in-kannada
#8
Mohan Kumar Kalaiah, Jayashree S Bhat
BACKGROUND AND OBJECTIVES: The present study was carried out to investigate the effect of vowel context on the recognition of Kannada consonants in quiet for young adults. SUBJECTS AND METHODS: A total of 17 young adults with normal hearing in both ears participated in the study. The stimuli included consonant-vowel syllables, spoken by 12 native speakers of Kannada. Consonant recognition task was carried out as a closed-set (fourteen-alternative forced-choice)...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942628/postoperative-mastoid-aeration-following-canal-wall-up-mastoidectomy-according-to-preoperative-middle-ear-disease-analysis-of-temporal-bone-computed-tomography-scans
#9
Oh Joon Kwon, Jae Moon Sung, Hwi Kyeong Jung, Chang Woo Kim
BACKGROUND AND OBJECTIVES: The aim of our study was to evaluate postoperative mastoid aeration according to the preoperative middle ear disease and investigate the factors affecting it. SUBJECTS AND METHODS: We retrospectively reviewed the high-resolution computed tomography (CT) scans of temporal bones that were taken 1 year after surgery. The postoperative mastoid aeration was evaluated according to the preoperative diagnosis, and classified into three groups: grade 1 (complete mastoid aeration), an air-filled epitympanum and mastoid cavity; grade 2 (partial mastoid aeration), an air-filled epitympanum and partially aerated mastoid cavity; and grade 3 (absence of mastoid aeration), no air space in the mastoid cavity...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28942306/systemic-mycobacterium-kansasii-infection-in-a-domestic-shorthair-cat
#10
S-H Lee, D-M Go, S-H Woo, H-T Park, E Kim, H S Yoo, D-Y Kim
A 1-year-old, female domestic shorthair cat was presented with anorexia, depression and weight loss, accompanied by multifocal nodules affecting the face, pinnae and periarticular tissue. Routine medical treatments were ineffective. The animal's physical condition continued to deteriorate and it finally died. Post-mortem examination revealed multifocal to coalescing firm nodules with occasional ulceration affecting the ears, peri-ocular areas, nasal planum, oral cavity and laryngopharyngeal region. Tan-coloured, firm, nodular lesions were also observed in the periarticular tissue, lungs and tracheobronchial and mediastinal lymph nodes...
August 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28942232/an-unusual-case-of-temporal-bone-encephalomeningocele-occurring-together-with-normal-pressure-hydrocephalus
#11
Bernard Tan Wen Sheng, David Low Yong Ming, Heng Wai Yuen
Temporal bone encephalomeningoceles are uncommon clinical entities that can be challenging to diagnose and treat. Common presenting complaints include symptoms of aural fullness, hearing loss, clear otorrhea and meningitis. Common etiologies are chronic middle ear disease and trauma. A significant proportion of cases are spontaneous, which occurs in relation to benign intracranial hypertension. Normal pressure hydrocephalus associated with temporal bone encepahomeningoceles has not been previously described...
September 20, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28942100/doppler-ultrasonography-can-be-useful-to-determine-the-etiology-of-idiopathic-sudden-sensorineural-hearing-loss
#12
Ahmet Mutlu, Isa Cam, Sinem Dasli, Murat Topdag
OBJECTIVE: This study aims to evaluate clinical features of both carotid and vertebral arteries in the idiopathic sudden sensorineural hearing loss (ISSNHL) patients and healthy individuals to contribute additional knowledge on vascular compromise theory. METHODS: This study was designed as a retrospective case control study in a tertiary referral center. 55 patients for ISSNHL and 35 healthy participants (70 ears) are involved to the study. All of the patients were evaluated for the systemic disorders and excluded other possible causes (autoimmune diseases, acoustic schwannoma, drug toxicity, etc) of ISSNHL...
September 20, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28941704/mir-194-is-involved-in-morphogenesis-of-spiral-ganglion-neurons-in-inner-ear-by-rearranging-actin-cytoskeleton-via-targeting-rhob
#13
Jintao Du, Xuemei Zhang, Hui Cao, Di Jiang, Xianren Wang, Wei Zhou, Kaitian Chen, Jiao Zhou, Hongyan Jiang, Luo Ba
Many microRNAs participate in the development, differentiation and function preservation of the embryonic and adult inner ear, but many details still need to be elucidated regarding the numerous microRNAs in the inner ear. Based on previous investigations on the microRNA profile in the inner ear, we confirmed that several microRNAs are expressed in the inner ear, and we detected the spatial expression of these microRNAs in the neonatal mouse inner ear. Then we focused on miR-194 for its specific expression with a dynamic spatiotemporal pattern during inner ear development...
September 20, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28940836/small-airway-involvement-in-the-late-allergic-response-in-asthma
#14
Henning Stenberg, Zuzana Diamant, Jaro Ankerst, Leif Bjermer, Ellen Tufvesson
BACKGROUND: Allergy and asthma are closely linked. Inhalation of allergen induces an early allergic response (EAR) within the airways of allergic asthmatic subjects, which is followed by a late allergic response (LAR) in approximately 50% of the subjects. The LAR is defined as a drop in forced expiratory volume in 1 s (FEV1 ) from baseline usually occurring 4-8 h after exposure, and is believed to affect small airways. However, FEV1 is insensitive to changes in small airway physiology...
September 21, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28940817/answer-to-shimizu-et%C3%A2-al-organ-involvement-pattern-suggests-subgroups-within-relapsing-polychondritis
#15
Jérémie Dion, Nathalie Costedoat-Chalumeau, Jean-Charles Piette
We read with interest the letter from Shimizu et al. regarding their large survey of 121 Japanese physicians following a total of 239 patients with relapsing polychondritis (RP). Using correlation matrix, they found that airway involvement (laryngo and tracheobronchial (TB)) was strongly associated with nasal chondritis whereas the relationship was inverse with external ear chondritis suggesting that the nasal and the auricular chondritis define two subgroups of RP patients. This article is protected by copyright...
September 21, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28940719/effect-of-availability-of-video-laryngoscopy-on-the-use-of-fiberoptic-intubation-in-school-aged-children-with-microtia
#16
Ichiro Kondo, Hidetsugu Kobayashi, Yoshihumi Suga, Akihiro Suzuki, Shuya Kiyama, Shoichi Uezono
BACKGROUND: With the increasing popularity of video laryngoscopy during intubation of pediatric patients with normal or difficult airways, fiberoptic-assisted tracheal intubation, traditionally considered the gold standard for difficult intubation, may become underused. AIM: We aimed to assess the use of airway management techniques before and after introduction of video laryngoscopy in a cohort of school-aged children with microtia, who are at increased risk of difficult intubation...
September 20, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28940518/sandwich-compression-with-rubbery-tourniquet-sheets-and-cotton-balls-for-auricular-pseudocyst
#17
Ming-Ying Wu, Chun-Bing Chen, Yi-Hsi Chen, Catherine Chang, Kai-Chieh Chan
OBJECTIVES/HYPOTHESIS: Pseudocyst of the auricle is a benign, noninflammatory cystic disease that is more common in Asians than in Caucasians. When managed conservatively, the results are often unsatisfactory and recurrences are common. We aimed to introduce a novel modified surgical method that involves a deroofing technique followed by a sandwich compression suture using two rubber tourniquet sheets and an iodine-soaked cotton ball for the treatment of auricular pseudocysts and to ascertain its effectiveness...
September 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28940480/thirty-day-morbidity-and-mortality-following-otologic-neurotologic-surgery-analysis-of-the-national-surgical-quality-improvement-program
#18
Zachary G Schwam, Elias Michaelides, Phoebe Kuo, Michael A Hajek, Benjamin L Judson, Christopher Schutt
OBJECTIVES/HYPOTHESIS: To determine the rate and timing of, as well as risk factors for, postoperative morbidity and mortality following otologic and neurotologic surgery. STUDY DESIGN: Retrospective cohort study. METHODS: A total of 1,381 patients were identified in the American College of Surgeons National Surgical Quality Improvement Program for the years 2005 to 2010. Simple summary statistics, χ(2) , and multivariable logistic regression were performed...
September 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28940090/dicipivirus-family-picornaviridae-in-wild-northern-white-breasted-hedgehog-erinaceus-roumanicus
#19
Gábor Reuter, Ákos Boros, Gábor Földvári, Sándor Szekeres, Róbert Mátics, Beatrix Kapusinszky, Eric Delwart, Péter Pankovics
Using random amplification and high-throughput sequencing technology a novel picornavirus with dicistronic genome organization and genetically related to canine picodicistrovirus (genus Dicipivirus, family Picornaviridae) was identified and characterized in Northern white-breasted hedgehogs. Hedgehog dicipivirus (hedgehog/H14/2015/HUN, MF188967) was detected in 15 (75%) of 20 faecal specimens by RT-PCR with high viral loads (up to 8.2x10(8) genomic copies/ml faeces). Hedgehog dicipivirus RNA was also identified in blood, ear skin, abdominal muscle and liver tissues...
September 22, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28938423/igfbp4-is-required-for-adipogenesis-and-influences-the-distribution-of-adipose-depots
#20
David E Maridas, Victoria E DeMambro, Phuong T Le, Subburaman Mohan, Clifford J Rosen
Insulin-like Growth Factor I (IGF-I) induces adipogenesis in vitro. IGF Binding Protein 4 (IGFBP4) is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. We previously reported that Igfbp4 null mice (Igfbp4-/-) had decreased fat proportions at 8 and 16 weeks of age. However, the mechanism leading to the reduced adiposity remains unknown. The purpose of this study was to elucidate how IGFBP4 mediates adipose tissue development in vivo. Our results showed that inguinal (iWAT) and gonadal (gWAT) white adipose tissues from Igfbp4-/- mice had decreased weights and Pparγ expression...
July 27, 2017: Endocrinology
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