Yves Dauvilliers, Gert Jan Lammers, Michel Lecendreux, Kiran Maski, Sujay Kansagra, Jed Black, Rupa Parvataneni, Abby Chen, Y Grace Wang, Giuseppe Plazzi
STUDY OBJECTIVES: To examine body mass index (BMI) changes associated with sodium oxybate treatment (SXB) in pediatric patients with narcolepsy with cataplexy who participated in a double-blind, placebo-controlled, randomized withdrawal study and an open-label continuation period (OLC). METHODS: Participants were aged 7-16 years at screening. SXB-naive participants titrated to twice-nightly dosing of SXB, then entered a 2-week stable-dose period; participants taking SXB at study entry entered a 3-week stable-dose period...
November 9, 2023: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine