keyword
https://read.qxmd.com/read/38472403/-overview-of-chronobiological-and-sleep-medical-aspects-of-depression-in-adolescents
#21
REVIEW
Neda Ghotbi, Aline Doreen Scherff, Ellen Greimel, Gerd Schulte-Körne
Changes in sleep are reported in adolescents with depression with a frequency of up to 71%. Aspects of chronobiology and sleep based on the current scientific literature are illustrated and summarized in this narrative review. The circadian clock synchronizes organisms to the light-dark structure of the environment. The individual synchronization is called "chronotype." Chronotype changes according to age, among other factors, and adolescents experience the latest chronotypes overall. The potential discrepancy between internal and external time is called "social jetlag...
March 12, 2024: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://read.qxmd.com/read/38471778/spectral-slope-and-lempel-ziv-complexity-as-robust-markers-of-brain-states-during-sleep-and-wakefulness
#22
JOURNAL ARTICLE
Christopher Höhn, Michael A Hahn, Janna D Lendner, Kerstin Hoedlmoser
Non-oscillatory measures of brain activity such as the spectral slope and Lempel-Ziv complexity are affected by many neurological disorders and modulated by sleep. A multitude of frequency ranges, particularly a broadband (encompassing the full spectrum) and narrowband approach, have been used especially for estimating the spectral slope. However, the effects of choosing different frequency ranges have not yet been explored in detail. Here, we evaluated the impact of sleep stage and task-engagement (resting, attention and memory) on slope and complexity in a narrow- (30 - 45Hz) and broadband (1 - 45Hz) frequency range in 28 healthy male human subjects (21...
March 12, 2024: ENeuro
https://read.qxmd.com/read/38470175/comprehensive-phenotypes-of-patients-with-syngap1-related-disorder-reveals-high-rates-of-epilepsy-and-autism
#23
JOURNAL ARTICLE
Kimberly Wiltrout, Elise Brimble, Annapurna Poduri
OBJECTIVE: To delineate the comprehensive phenotypic spectrum of SYNGAP1-related disorder in a large patient cohort aggregated through a digital registry. METHODS: We obtained de-identified patient data from an online registry. Data were extracted from uploaded medical records. We reclassified all SYNGAP1 variants using American College of Medical Genetics criteria and included patients with pathogenic/likely pathogenic (P/LP) single nucleotide variants or microdeletions incorporating SYNGAP1...
March 12, 2024: Epilepsia
https://read.qxmd.com/read/38470080/the-motor-dysfunction-seen-in-isolated-rem-sleep-behavior-disorder
#24
JOURNAL ARTICLE
Cristina Simonet, Laura Pérez-Carbonell, Miquel A Galmés-Ordinas, Brook F R Huxford, Harneek Chohan, Aneet Gill, Guy Leschziner, Andrew J Lees, Anette Schrag, Alastair J Noyce
BACKGROUND: Isolated Rapid Eye Movement (REM) sleep Behavior Disorder (iRBD) requires quantitative tools to detect incipient Parkinson's disease (PD). METHODS: A motor battery was designed and compared with the Movement Disorder Society-Unified Parkinson's Disease Rating Scale part III (MDS-UPDRS-III) in people with iRBD and controls. This included two keyboard-based tests (BRadykinesia Akinesia INcoordination tap test and Distal Finger Tapping) and two dual tasking tests (walking and finger tapping)...
March 12, 2024: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/38469992/the-effect-of-a-training-program-on-adolescents-%C3%A2-stress-levels-and-healthy-lifestyle-behaviors-during-the-covid-19-pandemic-a-randomized-controlled-study
#25
RANDOMIZED CONTROLLED TRIAL
Edanur Tar Bolacali, Derya Kaya Şenol
TOPIC: Adolescence is the period when people adopt healthy lifestyle behaviors and turn them into habits. Healthy lifestyle behaviors are a significant step toward a long and healthy life. PURPOSE: This study investigated the effect of a training program on adolescents' stress levels and healthy lifestyle behaviors during the COVID-19 pandemic. METHODS: This randomized controlled study was conducted between May and July 2021. The sample consisted of 100 adolescents living in a city in the south of Turkey...
May 2024: Journal of Child and Adolescent Psychiatric Nursing
https://read.qxmd.com/read/38469833/pain-care-at-home-to-amplify-function-protocol-article
#26
JOURNAL ARTICLE
Anne C Black, Sara N Edmond, Joseph W Frank, Audrey Abelleira, Jennifer L Snow, Danielle M Wesolowicz, William C Becker
Guidelines recommend strategies to optimize opioid medication safety, including frequent reassessment of the benefits and harms of long-term opioid therapy. Prescribers, who are predominantly primary care providers (PCPs), may lack the training or resources to implement these guideline-concordant practices. Two interventions have been designed to assist PCPs and tested within the Veterans Health Administration (VHA). Telemedicine Collaborative Management (TCM) provides primarily medication management support via care manager-prescriber teams...
March 12, 2024: Subst Use Addctn J
https://read.qxmd.com/read/38469290/involvement-of-limbic-structures-in-patients-with-isolated-rapid-eye-movement-sleep-behavior-disorder
#27
JOURNAL ARTICLE
D A Lee, H J Lee, K M Park
This study aimed to investigate the alterations in limbic structure volumes and limbic covariance network in patients with isolated rapid eye movement (REM) sleep behavior disorder (iRBD) and to compare them with healthy controls. We retrospectively enrolled 35 patients with iRBD and 35 healthy controls who underwent three-dimensional T1-weighted brain MRI. Volumetric analysis of subcortical limbic structures, including the hippocampus, amygdala, thalamus, mammillary body, hypothalamus, basal forebrain, septal nuclei, fornix, and nucleus accumbens, was performed...
April 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38469277/one-night-of-10-h-sleep-restores-vigilance-after-total-sleep-deprivation-the-role-of-delta-and-theta-power-during-recovery-sleep
#28
JOURNAL ARTICLE
Chao Hao, Mingzhu Li, Qian Ning, Ning Ma
A series of studies have demonstrated that impaired vigilance performance caused by total sleep deprivation could restore to baseline when recovery sleep is longer than the habitual sleep. However, it is unclear which factors on the recovery night affected the restoration of vigilance performance impaired by sleep deprivation. 22 participant's sleep electroencephalograms were recorded with polysomnography in 8-h baseline sleep and one-night 10-h recovery sleep following 36-h sleep deprivation. Participants completed a 10-min psychomotor vigilance task and subjective ratings after baseline and recovery sleep the following day...
April 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38469083/the-eveningness-chronotype-is-associated-with-nightmare-distress-and-dream-recall-a-cross-sectional-study
#29
JOURNAL ARTICLE
Yi-Seul Choo, Sang Wook Hong, Ga Eun Koo, Su-Hyun Han
Dreaming may be affected by sleep behavior; however, evidence of the effect of chronotypes on dreaming is limited. We investigated sleep patterns, dream recall, and nightmare distress according to chronotypes. This cross-sectional study retrospectively enrolled adult participants (age > 18 years) who visited a sleep laboratory between 2016 and 2021 and underwent standard polysomnography (PSG) and completed a self-reported questionnaire. Patients with major sleep disorders were excluded...
July 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38468418/cognitive-behavior-therapy-for-insomnia-for-untreated-hypertension-with-comorbid-insomnia-disorder-the-sleepright-clinical-trial
#30
JOURNAL ARTICLE
Andrew Sherwood, Christi Ulmer, Jade Q Wu, James A Blumenthal, Emma Herold, Patrick J Smith, Gary G Koch, Kristy Johnson, Anthony Viera, Jack Edinger, Alan Hinderliter
Insomnia and poor sleep are associated with an increased risk of developing cardiovascular disease (CVD) and its precursors, including hypertension. In 2022, the American Heart Association (AHA) added inadequate sleep to its list of health behaviors that increase the risk for CVD. It remains unknown, however, whether the successful treatment of insomnia and inadequate sleep can reduce heightened CVD risk. SLEEPRIGHT is a single-site, prospective clinical trial designed to evaluate whether the successful treatment of insomnia results in improved markers of CVD risk in patients with untreated hypertension and comorbid insomnia disorder...
March 11, 2024: Journal of Clinical Hypertension
https://read.qxmd.com/read/38467937/comprehensive-proteomics-of-csf-plasma-and-urine-identify-ddc-and-other-biomarkers-of-early-parkinson-s-disease
#31
JOURNAL ARTICLE
Jarod Rutledge, Benoit Lehallier, Pardis Zarifkar, Patricia Moran Losada, Marian Shahid-Besanti, Dan Western, Priyanka Gorijala, Sephira Ryman, Maya Yutsis, Gayle K Deutsch, Elizabeth Mormino, Alexandra Trelle, Anthony D Wagner, Geoffrey A Kerchner, Lu Tian, Carlos Cruchaga, Victor W Henderson, Thomas J Montine, Per Borghammer, Tony Wyss-Coray, Kathleen L Poston
Parkinson's disease (PD) starts at the molecular and cellular level long before motor symptoms appear, yet there are no early-stage molecular biomarkers for diagnosis, prognosis prediction, or monitoring therapeutic response. This lack of biomarkers greatly impedes patient care and translational research-L-DOPA remains the standard of care more than 50 years after its introduction. Here, we performed a large-scale, multi-tissue, and multi-platform proteomics study to identify new biomarkers for early diagnosis and disease monitoring in PD...
March 11, 2024: Acta Neuropathologica
https://read.qxmd.com/read/38466992/assessment-and-management-of-sleep-disturbance-in-palliative-care-settings
#32
JOURNAL ARTICLE
Megan S Jeon, Peter Allcroft, Linda Ruth Brown, David Currow, Slavica Kochovska, Anu Krishnan, Andrew Webster, Rachel Campbell
Background: Sleep disturbances, including insomnia, sleep-disordered breathing, and circadian rhythm disorders with potential consequences including excessive daytime somnolence and worsening fatigue, are prevalent yet largely under-measured and therefore under-managed problems in people receiving palliative care. This has the potential to negatively affect the person's functioning and quality of life. Objectives: We aimed to review the current practice of assessment and management of sleep disturbances in people with life-limiting illnesses in Australian and New Zealand palliative care settings, and to define areas for improvement in assessment and management of sleep disturbances and further research...
March 12, 2024: Journal of Palliative Medicine
https://read.qxmd.com/read/38466158/presynaptic-dopaminergic-imaging-characterizes-patients-with-rem-sleep-behavior-disorder-due-to-synucleinopathy
#33
JOURNAL ARTICLE
Dario Arnaldi, Pietro Mattioli, Stefano Raffa, Matteo Pardini, Federico Massa, Alex Iranzo, Andres Perissinotti, Aida Niñerola-Baizán, Carles Gaig, Monica Serradell, Amaia Muñoz-Lopetegi, Gerard Mayà, Claudio Liguori, Mariana Fernandes, Fabio Placidi, Agostino Chiaravalloti, Karel Šonka, Petr Dušek, David Zogala, Jiri Trnka, Bradley F Boeve, Toji Miyagawa, Val J Lowe, Tomoyuki Miyamoto, Masayuki Miyamoto, Monica Puligheddu, Michela Figorilli, Alessandra Serra, Michele T Hu, Johannes C Klein, Frederik Bes, Dieter Kunz, Valérie Cochen De Cock, Delphine de Verbizier, Giuseppe Plazzi, Elena Antelmi, Michele Terzaghi, Irene Bossert, Kristína Kulcsárová, Alessio Martino, Alessandro Giuliani, Marco Pagani, Flavio Nobili, Silvia Morbelli
OBJECTIVE: To apply a machine learning analysis to clinical and presynaptic dopaminergic imaging data of patients with rapid eye movement (REM) sleep behavior disorder (RBD) to predict the development of Parkinson disease (PD) and dementia with Lewy bodies (DLB). METHODS: In this multicenter study of the International RBD study group, 173 patients (mean age 70.5 ± 6.3 years, 70.5% males) with polysomnography-confirmed RBD who eventually phenoconverted to overt alpha-synucleinopathy (RBD due to synucleinopathy) were enrolled, and underwent baseline presynaptic dopaminergic imaging and clinical assessment, including motor, cognitive, olfaction, and constipation evaluation...
March 11, 2024: Annals of Neurology
https://read.qxmd.com/read/38465918/parasomnia-induced-by-lemborexant-a-case-report
#34
JOURNAL ARTICLE
Toshinori Nakamura, Yusuke Arai, Tetsuya Hagiwara, Ryosuke Kitoh, Daimei Sasayama, Shinsuke Washizuka
Lemborexant, an orexin receptor antagonist, is effective not only for sleep disorders but also for preventing and treating delirium. To date, no complex sleep-related behaviors due to lemborexant have been reported. Herein, we present the case of a 69-year-old male patient who was hospitalized for oral floor and tongue cancer and developed delirium after surgery; however, upon lemborexant dosage increase, used to treat insomnia, he developed abnormal nocturnal behavior. This symptom rapidly improved when lemborexant was discontinued...
March 11, 2024: International Clinical Psychopharmacology
https://read.qxmd.com/read/38465133/exploring-care-and-recovery-for-individuals-with-post-traumatic-stress-disorder-a-scoping-review
#35
REVIEW
Jennifer R Smith, Kyle J Drouillard, Angel M Foster
Most people experience trauma at some point in their lives. The sources of trauma can include accidents, natural disasters, physical or sexual assault, combat, torture, or the death of a loved one. Experiencing or witnessing any of these, or other terrifying events, may make one susceptible to developing post-traumatic stress disorder (PTSD), a trauma- and stressor-related mental health condition. The common symptoms and consequences of PTSD include intrusive and distressing thoughts, memories, or flashbacks related to the traumatic event; avoidance of situations, people, or activities that remind one of the traumatic event; irritability, sleep difficulties, or hypervigilance; feelings of guilt, shame, or fear; substance use; strains on relationships; and suicidal thoughts and behaviors...
February 2024: Curēus
https://read.qxmd.com/read/38463432/the-effects-of-service-dogs-for-children-with-autism-spectrum-disorder-and-their-caregivers-a-cross-sectional-study
#36
JOURNAL ARTICLE
Kerri E Rodriguez, Mandy Rispoli, Bridgette L Kelleher, Evan L MacLean, Marguerite E O'Haire
INTRODUCTION: Service dogs are an increasingly popular complementary intervention for children with autism spectrum disorder. However, despite increasing demand, there remains a lack of empirical research on their potential benefits. The purpose of this study was to evaluate the effects of service dogs on children with autism and their caregivers. METHODS: A total of N = 75 families of children with autism were recruited from a non-profit service dog provider in the US, including n = 39 families previously placed with a service dog and n = 36 families engaging in usual care while on the waitlist...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38462966/examining-the-association-of-breakfast-skipping-with-sleep-disturbance-mental-health-and-health-related-quality-of-life-data-from-the-2018-korean-community-health-survey
#37
JOURNAL ARTICLE
Sung Min Jung, Mee-Ri Lee
Objectives: This study aimed to explore the relationship between breakfast skipping and its effects on sleep disorders, mental health, and health-related quality of life among Korean adults. Methods: Utilizing data from the 2018 Korea Community Health Survey, this cross-sectional analysis included 173,272 adults aged 19 years and older. Instruments used for assessment included the Patient Health Questionnaire-9 for depression, the EuroQol 5-dimension (EQ-5D) for health-related quality of life, and the Pittsburgh Sleep Quality Index for sleep disorders...
March 11, 2024: Nutritional Neuroscience
https://read.qxmd.com/read/38461873/combined-effects-of-sleep-and-objectively-measured-daily-physical-activity-on-arterial-stiffness-in-middle-aged-and-older-adults
#38
JOURNAL ARTICLE
Youngju Choi, Keisei Kosaki, Nobuhiko Akazawa, Koichiro Tanahashi, Seiji Maeda
Although sleep quality and physical activity (PA) may influence on arterial stiffness, the combined effects of these two factors on arterial stiffness remain unknown. A total of 103 healthy middle-aged and older men and women (aged 50-83 years) with no history of cardiovascular disease and depression were included in this study. Arterial stiffness was measured using carotid-femoral pulse wave velocity (cfPWV), brachial-ankle PWV (baPWV), and femoral-ankle PWV (faPWV). Poor sleepers were defined as those with a Pittsburgh Sleep Quality Index score of >5...
March 8, 2024: Experimental Gerontology
https://read.qxmd.com/read/38461857/application-of-the-sleep-c-a-l-m-tool-for-assessing-nocturia-in-a-large-nationally-representative-cohort
#39
JOURNAL ARTICLE
Joseph U Boroda, Benjamin De Leon, Lakshay Khosla, Muchi D Chobufo, Syed N Rahman, Jason M Lazar, Jeffrey P Weiss, Thomas F Monaghan
PURPOSE: Nocturia significantly impacts patients' quality of life but remains insufficiently evaluated and treated. The "Sleep C.A.L.M." system categorizes the factors thought to collectively reflect most underlying causes of nocturia (Sleep disorders, Comorbidities, Actions [i.e., modifiable patient behaviors such as excess fluid intake], Lower urinary tract dysfunction, and Medications). The purpose of this study was to assess the association of nocturia with the Sleep C.A.L.M. categories using a nationally representative dataset...
February 2024: International Neurourology Journal
https://read.qxmd.com/read/38461678/group-based-sleep-trajectories-in-children-and-adolescents-a-systematic-review
#40
REVIEW
Yuhang Wang, Buqun Li, Chenggang Zhang, Orfeu M Buxton, Susan Redline, Xiaoyu Li
Sleep is crucial for health and development. Evidence indicates that sleep changes over time and distinct subgroups may experience different longitudinal patterns. This study systematically reviewed the studies that used latent trajectory modeling to investigate sleep trajectories of children and adolescents aged 0-18 years, and summarized the associated determinants and health-related outcomes. We searched PubMed, Embase, CENTRAL, PsycINFO, and Web of Science, identifying 46 articles that met our criteria...
February 29, 2024: Sleep Medicine Reviews
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