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https://www.readbyqxmd.com/read/28079758/concussion-in-ice-hockey-current-gaps-and-future-directions-in-an-objective-diagnosis
#1
Aynsley M Smith, Michael J Stuart, William O Roberts, David W Dodick, Jonathan T Finnoff, Janelle K Jorgensen, David A Krause
OBJECTIVE: This review provides an update on sport-related concussion (SRC) in ice hockey and makes a case for changes in clinical concussion evaluation. Standard practice should require that concussions be objectively diagnosed and provide quantitative measures of the concussion injury that will serve as a platform for future evidence-based treatment. METHODS: The literature was surveyed to address several concussion-related topics: research in ice hockey-related head trauma, current subjective diagnosis, promising components of an objective diagnosis, and current and potential treatments...
January 10, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28060291/optimization-of-a-quantitative-micro-neutralization-assay
#2
Yipu Lin, Yan Gu, John W McCauley
The micro-neutralization (MN) assay is a standard technique for measuring the infectivity of the influenza virus and the inhibition of virus replication. In this study, we present the protocol of an imaging-based MN assay to quantify the true antigenic relationships between viruses. Unlike typical plaque reduction assays that rely on visible plaques, this assay quantitates the entire infected cell population of each well. The protocol matches the virus type or subtype with the selection of cell lines to achieve maximum infectivity, which enhances sample contrast during imaging and image processing...
December 14, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28049411/accelerating-metagenomic-read-classification-on-cuda-enabled-gpus
#3
Robin Kobus, Christian Hundt, André Müller, Bertil Schmidt
BACKGROUND: Metagenomic sequencing studies are becoming increasingly popular with prominent examples including the sequencing of human microbiomes and diverse environments. A fundamental computational problem in this context is read classification; i.e. the assignment of each read to a taxonomic label. Due to the large number of reads produced by modern high-throughput sequencing technologies and the rapidly increasing number of available reference genomes software tools for fast and accurate metagenomic read classification are urgently needed...
January 3, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28048381/su-f-p-41-iomp-new-professional-journal-medical-physics-international-initial-results
#4
S Tabakov, P Sprawls
PURPOSE: The number of professional and educational sessions and presentations at World Congresses (WC) doubled during the past 12 years. Alongside this, many new e-learning and related initiatives underpinned the global growth of medical physicists. A number of meetings discussed the need of an international forum to discuss medical physics education and professional development. In 2013 IOMP initiated a new Journal for the purpose - MEDICAL PHYSICS INTERNATIONAL (MPI) - a free access e-publication (www...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047651/su-f-j-100-standardized-biodistribution-template-for-nuclear-medicine-dosimetry-collection-and-reporting
#5
A Kesner, G Poli, S Beykan, M Lassman
PURPOSE: As the field of Nuclear Medicine moves forward with efforts to integrate radiation dosimetry into clinical practice we can identify the challenge posed by the lack of standardized dose calculation methods and protocols. All personalized internal dosimetry is derived by projecting biodistribution measurements into dosimetry calculations. In an effort to standardize organization of data and its reporting, we have developed, as a sequel to the EANM recommendation of "Good Dosimetry Reporting", a freely available biodistribution template, which can be used to create a common point of reference for dosimetry data...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047435/mo-de-bra-06-3d-image-acquisition-and-reconstruction-explained-with-online-animations
#6
A Kesner
PURPOSE: Understanding the principles of 3D imaging and image reconstruction is fundamental to the field of medical imaging. Clinicians, technologists, physicists, patients, students, and inquisitive minds all stand to benefit from greater comprehension of the supporting technologies. To help explain the basic principles of 3D imaging, we developed multi-frame animations that convey the concepts of tomographic imaging. The series of free (gif) animations are accessible online, and provide a multimedia introduction to the main concepts of image reconstruction...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27984423/evaluation-of-medication-mediated-effects-in-pharmacoepidemiology
#7
Eric J Tchetgen Tchetgen, Kelesitse Phiri
Medical conditions such as epilepsy or infection with human immunodeficiency virus (HIV) are known to be associated with a spectrum of adverse health outcomes if not appropriately managed by efficacious treatment and care. Medications for such conditions can be potent, and their use might sometimes have unintended health consequences. Prominent examples have emerged in HIV perinatal research in which use of antiretroviral treatment during pregnancy to treat maternal HIV infection and prevent transmission of the virus to the fetus have been shown to be associated with adverse birth outcomes...
December 12, 2016: Epidemiology
https://www.readbyqxmd.com/read/27973671/feasibility-of-obtaining-measures-of-lifestyle-from-a-smartphone-app-the-myheart-counts-cardiovascular-health-study
#8
Michael V McConnell, Anna Shcherbina, Aleksandra Pavlovic, Julian R Homburger, Rachel L Goldfeder, Daryl Waggot, Mildred K Cho, Mary E Rosenberger, William L Haskell, Jonathan Myers, Mary Ann Champagne, Emmanuel Mignot, Martin Landray, Lionel Tarassenko, Robert A Harrington, Alan C Yeung, Euan A Ashley
Importance: Studies have established the importance of physical activity and fitness, yet limited data exist on the associations between objective, real-world physical activity patterns, fitness, sleep, and cardiovascular health. Objectives: To assess the feasibility of obtaining measures of physical activity, fitness, and sleep from smartphones and to gain insights into activity patterns associated with life satisfaction and self-reported disease. Design, Setting, and Participants: The MyHeart Counts smartphone app was made available in March 2015, and prospective participants downloaded the free app between March and October 2015...
December 14, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27930392/pain-catastrophizing-is-not-associated-with-spinal-nociceptive-processing-in-people-with-chronic-widespread-pain
#9
David A Rice, Rosalind S Parker, Gwyn N Lewis, Michal T Kluger, Peter J McNair
OBJECTIVES: Pain catastrophizing has been associated with higher pain intensity, increased risk of developing chronic pain and poorer outcomes after pain treatments. Despite this, the mechanisms by which pain catastrophizing influences pain remain poorly understood. It has been hypothesised that pain catastrophizing may impair descending inhibition of spinal level nociception. The aims of this study were to compare spinal nociceptive processing in people with chronic widespread pain and pain free controls and examine potential relationships between measures of pain catastrophizing and spinal nociception...
December 7, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27920726/hrvanalysis-a-free-software-for-analyzing-cardiac-autonomic-activity
#10
Vincent Pichot, Frédéric Roche, Sébastien Celle, Jean-Claude Barthélémy, Florian Chouchou
Since the pioneering studies of the 1960s, heart rate variability (HRV) has become an increasingly used non-invasive tool for examining cardiac autonomic functions and dysfunctions in various populations and conditions. Many calculation methods have been developed to address these issues, each with their strengths and weaknesses. Although, its interpretation may remain difficult, this technique provides, from a non-invasive approach, reliable physiological information that was previously inaccessible, in many fields including death and health prediction, training and overtraining, cardiac and respiratory rehabilitation, sleep-disordered breathing, large cohort follow-ups, children's autonomic status, anesthesia, or neurophysiological studies...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27902529/perceived-exertion-during-exercise-is-associated-with-children-s-energy-intake
#11
S Nicole Fearnbach, Travis D Masterson, Haley A Schlechter, Eric Loken, Danielle S Downs, David Thivel, Kathleen L Keller
PURPOSE: To examine the individual-level factors that predict energy intake (EI) following imposed exercise (EX) and sedentary time (SED) in children. METHODS: Healthy-weight children ages 9-12 years (n = 20) reported to the laboratory for 1 baseline and 2 experimental visits (EX and SED) each separated by 1 week in a randomized crossover design. Percent body fat, weight (kg), and height (m) were used to calculate fat-mass index (FM index) and fat-free mass index (FFM index; kg/m)...
November 29, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27893485/peripheral-neuropathic-pain-a-mechanism-related-organizing-principle-based-on-sensory-profiles
#12
Ralf Baron, Christoph Maier, Nadine Attal, Andreas Binder, Didier Bouhassira, Giorgio Cruccu, Nanna B Finnerup, Maija Haanpää, Per Hansson, Philipp Hüllemann, Troels S Jensen, Rainer Freynhagen, Jeffrey D Kennedy, Walter Magerl, Tina Mainka, Maren Reimer, Andrew S C Rice, Märta Segerdahl, Jordi Serra, Sören Sindrup, Claudia Sommer, Thomas Tölle, Jan Vollert, Rolf-Detlef Treede
Patients with neuropathic pain are heterogeneous in etiology, pathophysiology and clinical appearance. They exhibit a variety of pain-related sensory symptoms and signs (sensory profile). Different sensory profiles might indicate different classes of neurobiological mechanisms and hence subgroups with different sensory profiles might respond differently to treatment.The aim of the investigation was to identify subgroups in a large sample of neuropathic pain patients using hypothesis-free statistical methods on the database of three large multi-national research networks (German Research Network on Neuropathic Pain (DFNS), IMI-Europain, Neuropain)...
November 3, 2016: Pain
https://www.readbyqxmd.com/read/27875377/spinal-cord-stimulation-for-refractory-angina-pectoris-a-systematic-review-and-meta-analysis
#13
Xiaoxiao Pan, Hongguang Bao, Yanna Si, Chenjie Xu, Hao Chen, Xianzhong Gao, Xinyi Xie, Yajie Xu, Fan Sun, Lingqing Zeng
OBJECTIVES: Parasthesia free stimulation, such as high frequency and burst have been demonstrated as effective therapies for neuropathic pain. The aim of this meta-analysis was to evaluate the efficacy and safety of conventional spinal cord stimulation (SCS) in the treatment of refractory angina pectoris (RAP). METHODS: Relevant randomized controlled trial (RCT) studies that investigated SCS for patients with RAP were comprehensively searched in Medline, Pubmed, Embase, and Cochrane Library...
November 21, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27830889/sectioned-images-and-surface-models-of-a-cadaver-for-understanding-the-free-vascularized-anterior-rib-flap
#14
Dong Sun Shin, Hyung Jun Kim, Bong Chul Kim
BACKGROUND: The purpose of this study is to describe the vascularized anterior rib flap on sectioned images and surface models using Visible Korean for medical education and clinical training in the field of mandibular reconstructive surgery. MATERIALS AND METHODS: Serially sectioned images of the thorax were obtained from a cadaver. Significant structures in the sectioned images were outlined and stacked to create a surface model. RESULTS: The PDF file (8...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27826133/safe-sex-messages-within-dating-and-entertainment-smartphone-apps-a-review
#15
REVIEW
Evelyn Tzu-Yen Huang, Henrietta Williams, Jane S Hocking, Megan Sc Lim
BACKGROUND: Smartphone apps provide a new platform for entertainment, information distribution, and health promotion activities, as well as for dating and casual sexual encounters. Previous research has shown high acceptability of sexual health interventions via smartphone apps; however, sexual health promotion apps were infrequently downloaded and underused. Integrating sexual health promotion into established apps might be a more effective method. OBJECTIVE: The objective of our study was to critically review popular sex-related apps and dating apps, in order to ascertain whether they contain any sexual health content...
November 8, 2016: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/27821265/tetrahedral-node-for-transmission-line-modeling-tlm-applied-to-bio-heat-transfer
#16
Hugo F M Milan, Kifle G Gebremedhin
Transmission-Line Modeling (TLM) is a numerical method used to solve complex and time-domain bio-heat transfer problems. In TLM, parallelepipeds are used to discretize three-dimensional problems. The drawback in using parallelepiped shapes is that instead of refining only the domain of interest, a large additional domain would also have to be refined, which results in increased computational time and memory space. In this paper, we developed a tetrahedral node for TLM applied to bio-heat transfer that does not have the drawback associated with the parallelepiped node...
October 31, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27807048/snpgenesets-an-r-package-for-genome-wide-study-annotation
#17
Hao Mei, Lianna Li, Fan Jiang, Jeannette Simino, Michael Griswold, Thomas Mosley, Shijian Liu
Genome-wide studies (GWS) of SNP associations and differential gene expressions have generated abundant results; next-generation sequencing technology has further boosted the number of variants and genes identified. Effective interpretation requires massive annotation and downstream analysis of these genome-wide results, a computationally challenging task. We developed the snpGeneSets package to simplify annotation and analysis of GWS results. Our package integrates local copies of knowledge bases for SNPs, genes, and gene sets, and implements wrapper functions in the R language to enable transparent access to low-level databases for efficient annotation of large genomic data...
December 7, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/27798424/considering-the-optimal-timing-of-breast-reconstruction-with-abdominal-flaps-with-adjuvant-irradiation-in-370-consecutive-pedicled-transverse-rectus-abdominis-myocutaneous-flap-and-free-deep-inferior-epigastric-perforator-flap-performed-in-a-chinese-oncology
#18
Shanshan He, Jian Yin, Geoffrey L Robb, Jingyan Sun, Xuehui Zhang, Haixin Li, Jing Liu, Chunyong Han
PURPOSE: There is an ongoing debate on the optimal sequence of radiation and breast reconstruction. The purpose of this article was to (a) assess the impact of radiation on autologous breast reconstruction and (b) analyze the best timing for autologous breast reconstruction in the setting of radiation in a Chinese population. METHODS: A retrospective review of patients undergoing breast reconstruction with autologous lower abdominal flaps between 2001 and 2014 in the Tianjin Medical University and Cancer Hospital was performed...
October 28, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27794554/rnacentral-a-comprehensive-database-of-non-coding-rna-sequences
#19
(no author information available yet)
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species...
January 4, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/27749456/efficacy-and-safety-of-bevacizumab-containing-therapy-in-newly-diagnosed-ovarian-cancer-rosia-single-arm-phase-3b-study
#20
Amit M Oza, Frédéric Selle, Irina Davidenko, Jacob Korach, Cesar Mendiola, Patricia Pautier, Ewa Chmielowska, Aristotelis Bamias, Andrea DeCensi, Zanete Zvirbule, Antonio González-Martín, Roberto Hegg, Florence Joly, Claudio Zamagni, Angiolo Gadducci, Nicolas Martin, Stephen Robb, Nicoletta Colombo
OBJECTIVE: The aim of this study was to assess the safety and efficacy of extending bevacizumab therapy beyond 15 months in nonprogressive ovarian cancer. PATIENTS AND METHODS: In this multinational prospective single-arm study (ClinicalTrials.gov NCT01239732), eligible patients had International Federation of Gynecology and Obstetrics stage IIB to IV or grade 3 stage I to IIA ovarian cancer without clinical signs or symptoms of gastrointestinal obstruction or history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within the preceding 6 months...
January 2017: International Journal of Gynecological Cancer
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