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https://www.readbyqxmd.com/read/28634724/darma-software-for-dual-axis-rating-and-media-annotation
#1
Jeffrey M Girard, Aidan G C Wright
Continuous measurement systems provide a means of measuring dynamic behavioral and experiential processes as they play out over time. DARMA is a modernized continuous measurement system that synchronizes media playback and the continuous recording of two-dimensional measurements. These measurements can be observational or self-reported and are provided in real-time through the manipulation of a computer joystick. DARMA also provides tools for reviewing and comparing collected measurements and for customizing various settings...
June 20, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28634004/minyoo-matata-the-vicious-worm-a-taenia-solium-computer-based-health-education-tool-in-swahili
#2
Chiara Trevisan, Eric M Fèvre, Maurice Owiny, Isaac Ngere, Maria Vang Johansen
Lack of knowledge is one of the main risk factors for the spread of the zoonotic parasite Taenia solium. The computer-based health-education tool 'The Vicious Worm' was developed to create awareness and provide evidence-based health education as a specific measure in control strategies. To increase the reach of the tool, a new version in Swahili was developed and can now be downloaded for free from http://theviciousworm.sites.ku.dk.
June 17, 2017: Trends in Parasitology
https://www.readbyqxmd.com/read/28627465/differential-proteome-analysis-of-hippocampus-and-temporal-cortex-using-label-free-based-2d-lc-ms-ms
#3
Xiaoyan Liu, Zhengguang Guo, Wei Liu, Wei Sun, Chao Ma
Hippocampus and temporal cortex are important brain regions, which play distinct, but complimentary roles in mediating learning and memory. Herein, we utilized label-free differential proteome strategy to explore function of normal human hippocampus and temporal cortex in learning and memory. As a result, a total of 5529 and 5702 proteins were identified in hippocampus and temporal cortex, respectively, 516 of which were significantly differential expressed, with abundance span 5 orders of magnitudes. Pathways analysis showed that temporal cortex was involved in growth of axons growth and synapse density regulation, through which could regulate long-term potentiation and long-term retention of trace memory...
June 13, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28622818/use-of-a-smartphone-application-to-screen-for-depression-and-suicide-in-south-korea
#4
Seung-Ho Jang, Young Sup Woo, Jeong-Wan Hong, Bo-Hyun Yoon, Tae-Yeon Hwang, Moon-Doo Kim, Sang-Yeol Lee, Won-Myong Bahk
OBJECTIVE: This is a cross-sectional study using a free depression and suicide screening smartphone application, which contains the data from the Center for Epidemiological Studies-Depression (CES-D) and a Suicide Behaviors Questionnaire-Revised (SBQ-R). METHOD: The free application was downloaded worldwide from Apple's App Store and Android Market, and the participants who downloaded the application were actively measured. RESULTS: The subjects totaled 208,683 men and women...
May 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28619296/understanding-north-american-yoga-therapists-attitudes-skills-and-use-of-evidence-based-practice-a-cross-national-survey
#5
Marlysa Sullivan, Matthew Leach, James Snow, Steffany Moonaz
INTRODUCTION: Little is known about the adoption of evidence-based practice (EBP) by yoga therapists (YTs). OBJECTIVE: To determine the attitudes, skills, training, use, barriers and facilitators to the use of EBP amongst North American YTs DESIGN: Cross-sectional, descriptive survey METHODS: Self-identified YTs practicing in North America were invited to participate in an online survey. YT attitudes, skills, training, utilisation, barriers to use, and facilitators of EBP use were measured using the 84-item Evidence-Based practice Attitude and utilization SurvEy (EBASE)...
June 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28613845/spatial-and-temporal-trends-in-global-emissions-of-nitrogen-oxides-from-1960-to-2014
#6
Tianbo Huang, Xi Zhu, Qirui Zhong, Xiao Yun, Wenjun Meng, Bengang Li, Jianmin Ma, Eddy Y Zeng, Shu Tao
The quantification of nitrogen oxide (NOx) emissions is critical for air quality modeling. Based on updated fuel consumption and emission factor databases, a global emission inventory was compiled with high spatial (0.10.1), temporal (monthly), and source (87 sources) resolutions for the period 1960 to 2014. The monthly emission data have been uploaded online (http://inventory.pku.edu.cn), along with a number of other air pollutant and greenhouse gas data for free download. Differences in source profiles, not global total quantities, between our results and those reported previously were found...
June 14, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28585144/weighted-gene-co-expression-network-analysis-of-gene-modules-for-the-prognosis-of-esophageal-cancer
#7
Cong Zhang, Qian Sun
Esophageal cancer is a common malignant tumor, whose pathogenesis and prognosis factors are not fully understood. This study aimed to discover the gene clusters that have similar functions and can be used to predict the prognosis of esophageal cancer. The matched microarray and RNA sequencing data of 185 patients with esophageal cancer were downloaded from The Cancer Genome Atlas (TCGA), and gene co-expression networks were built without distinguishing between squamous carcinoma and adenocarcinoma. The result showed that 12 modules were associated with one or more survival data such as recurrence status, recurrence time, vital status or vital time...
June 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28581279/improved-software-to-browse-the-serial-medical-images-for-learning
#8
Koojoo Kwon, Min Suk Chung, Jin Seo Park, Byeong Seok Shin, Beom Sun Chung
The thousands of serial images used for medical pedagogy cannot be included in a printed book; they also cannot be efficiently handled by ordinary image viewer software. The purpose of this study was to provide browsing software to grasp serial medical images efficiently. The primary function of the newly programmed software was to select images using 3 types of interfaces: buttons or a horizontal scroll bar, a vertical scroll bar, and a checkbox. The secondary function was to show the names of the structures that had been outlined on the images...
July 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28559222/mobile-app-design-development-and-publication-for-adverse-drug-reaction-assessments-of-causality-severity-and-preventability
#9
Muslimah Ithnin, Mohd Dzulkhairi Mohd Rani, Zuraidah Abd Latif, Paveethra Kani, Asmalita Syaiful, Khairun Nain Nor Aripin, Tengku Amatullah Madeehah Tengku Mohd
BACKGROUND: Adverse drug reactions (ADRs) cause significant morbidity and mortality. Improved assessment of ADRs to identify the causal relationship, the severity, and the preventability will aid ADRs prevention or reduce patient burden. OBJECTIVE: The aim of this study was to develop mobile apps in assisting clinical decision in ADR assessments of causality, severity, and preventability using validated tools. The usability of the apps was assessed. METHODS: We designed mobile apps using validated assessment tools for ADRs...
May 30, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28549078/herod-a-human-ethnic-and-regional-specific-omics-database
#10
Xian Zeng, Lin Tao, Zhang Peng, Chu Qin, Shangying Chen, Weidong He, Ying Tan, Hong Xia Liu, Sheng Yong Yang, Zhe Chen, Yu Yang Jiang, Yu Zong Chen
Motivation: Genetic and gene expression variations within and between populations and across geographical regions have substantial effects on the biological phenotypes, diseases, and therapeutic response. The development of precision medicines can be facilitated by the OMICS studies of the patients of specific ethnicity and geographic region. However, there is an inadequate facility for broadly and conveniently accessing the ethnic and regional specific OMICS data. Results: Here, we introduced a new free database, HEROD, a human ethnic and regional specific OMICS database...
May 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28548922/development-of-ergonomics-audits-for-bagging-haul-truck-and-maintenance-and-repair-operations-in-mining
#11
Patrick G Dempsey, Jonisha Pollard, William L Porter, Alan Mayton, John R Heberger, Sean Gallagher, Leanna Reardon, Colin G Drury
The development and testing of ergonomics and safety audits for small and bulk bag filling, haul truck and maintenance and repair operations in coal preparation and mineral processing plants found at surface mine sites is described. The content for the audits was derived from diverse sources of information on ergonomics and safety deficiencies including: analysis of injury, illness and fatality data and reports; task analysis; empirical laboratory studies of particular tasks; field studies and observations at mine sites; and maintenance records...
June 18, 2017: Ergonomics
https://www.readbyqxmd.com/read/28537669/e2f2-induces-mcm4-ccne2-and-whsc1-upregulation-in-ovarian-cancer-and-predicts-poor-overall-survival
#12
L Xie, T Li, L-H Yang
OBJECTIVE: To explore the genes co-upregulated with E2F2 in ovarian cancer and their association with survival outcomes in ovarian cancer patients. MATERIALS AND METHODS: The raw data of GDS3592 was downloaded from GEO datasets for reanalysis. The overlapping subset between the top 150 upregulated genes in ovarian cancer epithelial cells (CEPIs) and the E2F2 positively correlated genes (Pearson's r≥0.5) in ovarian cancer cohort in TCGA was identified. The association between E2F2, MCM4, CCNE2 and WHSC1 and overall survival (OS) and recurrence-free survival (RFS) in ovarian cancer patients were assessed using Kaplan-Meier plotter...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28537202/self-assessment-of-independence-in-older-people
#13
Pierre Koskas, B Wolfowicz
BACKGROUND: E-health initiatives on the Internet can be used to provide support to people with chronic diseases and to their caregivers. In 2014/2015, we created a free website called jesuisautonome.fr where older people, or their carers on their behalf, can assess their independence in daily living by filling out a simple questionnaire. OBJECTIVES: To evaluate the interest of the public in websites of this kind, by analysing home care plans obtained via the self-assessment questionnaire...
January 1, 2017: HIM Journal
https://www.readbyqxmd.com/read/28535189/predicting-accurate-contacts-in-thousands-of-pfam-domain-families-using-pconsc3
#14
Mirco Michel, Marcin J Skwark, David Menéndez Hurtado, Magnus Ekeberg, Arne Elofsson
Motivation: A fewyears ago it was shown that by using amaximumentropy approach to describe couplings between columns in a multiple sequence alignment it is possible to significantly increase the accuracy of residue contact predictions. For very large protein families with more than 1000 effective sequences the accuracy is sufficient to produce accurate models of proteins as well as complexes. Today, for about half of all Pfam domain families no structure is known, but unfortunately most of these families have at most a few hundred members, i...
May 23, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28529712/looking-into-pandora-s-box-the-content-of-sci-hub-and-its-usage
#15
Bastian Greshake
Despite the growth of Open Access, potentially illegally circumventing paywalls to access scholarly publications is becoming a more mainstream phenomenon. The web service Sci-Hub is amongst the biggest facilitators of this, offering free access to around 62 million publications. So far it is not well studied how and why its users are accessing publications through Sci-Hub. By utilizing the recently released corpus of Sci-Hub and comparing it to the data of  ~28 million downloads done through the service, this study tries to address some of these questions...
2017: F1000Research
https://www.readbyqxmd.com/read/28518173/simultaneous-quantification-of-n-and-o-glycans-using-a-solid-phase-method
#16
Shuang Yang, Yingwei Hu, Lori Sokoll, Hui Zhang
Glycosylation has a pivotal role in a diverse range of biological activities, modulating the structure and function of proteins. Glycogens coupled to the nitrogen atom (N-linked) of asparagine side chains or to the oxygen atom (O-linked) of serine and threonine side chains represent the two major protein glycosylation forms. N-glycans can be released by glycosidases, whereas O-glycans are often cleaved by chemical reaction. However, it is challenging to combine these enzymatic and chemical reactions in order to analyze both N- and O-glycans...
June 2017: Nature Protocols
https://www.readbyqxmd.com/read/28509812/ospemifene-s-effects-on-lipids-and-coagulation-factors-a-post-hoc-analysis-of-phase-2-and-3-clinical-trial-data
#17
David F Archer, Corrado Altomare, Wei Jiang, Susannah Cort
OBJECTIVE: To evaluate the effect of ospemifene 60 mg on the lipid and coagulation parameters of postmenopausal women using data from five phase 2 and 3 clinical trials. METHODS: Data for lipids and coagulation factors for 2,166 postmenopausal women were pooled from five randomized, placebo-controlled studies. Lipid and coagulation parameters included in this analysis were total cholesterol, high-density lipoproteins (HDL), low-density lipoproteins (LDL), triglycerides, activated partial thromboplastin time (aPTT), fibrinogen, antithrombin antigen, protein C Ag, and protein S Ag free...
May 15, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28509710/ultrasound-guided-pericardiocentesis-a-novel-parasternal-approach
#18
Adi Osman, Tan Wan Chuan, Jamalludin Ab Rahman, Gabriele Via, Guido Tavazzi
OBJECTIVE: The aim of this study was to evaluate a novel pericardiocentesis technique using an in-plane parasternal medial-to-lateral approach with the use of a high-frequency probe in patients with cardiac tamponade. BACKGROUND: Echocardiography is pivotal in the diagnosis of pericardial effusion and tamponade physiology. Ultrasound guidance for pericardiocentesis is currently considered the standard of care. Several approaches have been described recently, which differ mainly on the site of puncture (subxiphoid, apical, or parasternal)...
May 15, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28505005/gastric-cancer-with-primitive-enterocyte-phenotype-an-aggressive-subgroup-of-intestinal-type-adenocarcinoma
#19
Sho Yamazawa, Tetsuo Ushiku, Aya Shinozaki-Ushiku, Akimasa Hayashi, Akiko Iwasaki, Hiroyuki Abe, Amane Tagashira, Hiroharu Yamashita, Yasuyuki Seto, Hiroyuki Aburatani, Masashi Fukayama
A primitive cell-like gene expression signature is associated with aggressive phenotypes of various cancers. We assessed the expression of phenotypic markers characterizing primitive cells and its correlation with clinicopathologic and molecular characteristics in gastric cancer. Immunohistochemical analysis of a panel of primitive phenotypic markers, including embryonic stem cell markers (OCT4, NANOG, SALL4, CLDN6, and LIN28) and known oncofetal proteins (AFP and GPC3), was performed using tissue microarray on 386 gastric cancers...
May 12, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28503199/the-aachen-fall-prevention-app-a-smartphone-application-app-for-the-self-assessment-of-elderly-patients-at-risk-for-ground-level-falls
#20
Peter Rasche, Alexander Mertens, Christina Bröhl, Sabine Theis, Tobias Seinsch, Matthias Wille, Hans-Christoph Pape, Matthias Knobe
BACKGROUND: Fall incidents are a major problem for patients and healthcare. The "Aachen Fall Prevention App" (AFPA) represents the first mobile Health (mHealth) application (app) empowering older patients (persons 50+ years) to self-assess and monitor their individual fall risk. Self-assessment is based on the "Aachen Fall Prevention Scale," which consists of three steps. First, patients answer ten standardized yes-no questions (positive criterion ≥ 5 "Yes" responses). Second, a ten-second test of free standing without compensatory movement is performed (positive criterion: compensatory movement)...
2017: Patient Safety in Surgery
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