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https://www.readbyqxmd.com/read/29331797/application-of-polyacrylamide-gel-as-a-new-membrane-in-electromembrane-extraction-for-the-quantification-of-basic-drugs-in-breast-milk-and-wastewater-samples
#1
Sakine Asadi, Hadi Tabani, Saeed Nojavan
Introducing new membranes with green chemistry approach seems to be a great challenge for the development of a practical method in separation science. In this regard, for the first time, polyacrylamide gel as a new membrane in electromembrane extraction (EME) was used for the extraction of three model basic drugs (pseudoephedrine (PSE), lidocaine (LID), and propranolol (PRO)), followed by HPLC-UV. In comparison with conventional EME, in this method neither organic solvent nor carrier agents were used for extraction of mentioned drugs...
January 9, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29304316/best-practices-to-limit-contamination-of-donor-milk-in-a-milk-bank
#2
Elizabeth B Froh, Jill Vanderpool, Diane L Spatz
Human milk donated to a milk bank can become contaminated in a number of ways, but processes exist to eradicate pathogenic bacterial growth. Donor human milk may be cultured before or after pasteurization or both. The purpose of this article is to describe standard operations of the Mothers' Milk Bank of the Children's Hospital of Philadelphia, best practices to limit the bacterial contamination of donor human milk, and implications for future research.
January 2, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29287170/outcomes-associated-with-type-of-milk-supplementation-among-late-preterm-infants
#3
Rebecca Mannel, Jennifer D Peck
OBJECTIVE: To assess whether type of milk supplementation provided to breastfeeding late preterm infants was associated with hospital length of stay (LOS) or breastfeeding status at discharge. DESIGN: Retrospective chart review. SETTING: Tertiary care teaching hospital in the southern United States. PARTICIPANTS: Late preterm infants 35 0/7 to 36 6/7 weeks gestational age (N = 183) admitted to the mother-baby unit between November 1, 2014, and October 31, 2016...
December 26, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29280369/characteristics-of-the-regional-human-milk-bank-in-poland-donors-recipients-and-nutritional-value-of-human-milk
#4
Olga Barbarska, Monika Zielińska, Beata Pawlus, Aleksandra Wesołowska
Background: In case of shortage of breast milk despite proper lactation care or the poor state of the mother’s health, breast milk from human milk bank is recommended for feeding preterm infants Objective: This study retrospectively evaluated the first year of the operation of the Regional Human Milk Bank Material and methods: Data concerning donors was collected in the human milk bank during the cooperation. The clinical characteristics of the recipients was made on the basis of medical documentation from the Holy Family Hospital in Warsaw, Poland...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/29275815/human-milk-and-necrotizing-enterocolitis
#5
Aloka L Patel, Jae H Kim
NEC is a multifactorial disease that occurs when multiple risk factors and/or stressors overlap, leading to profound inflammation and intestinal injury. Human milk feedings, both from the infant's mother and donor human milk, have been associated with reductions in NEC in preterm infants. This article will review the protective factors in human milk, clinical studies of human milk and NEC, and practices to enhance human milk use in neonatal intensive care units.
February 2018: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/29222900/comparisons-of-proteomic-profiles-of-whey-protein-between-donor-human-milk-collected-earlier-than-3-months-and-6-months-after-delivery
#6
Won-Ho Hahn, Joon-Hwan Song, Jong-Bok Seo, Jung Eun Lee, Jeong-Sang Lee, Seunghyun Song, Joohyun Lee, Nam Mi Kang
BACKGROUND AND OBJECTIVES: Human milk has nutritional, protective, and developmental advantages for premature infants. However, proteomic information of low abundant protein of donor milk is insufficient. The purpose of this study is to analyze and compare the proteome of low abundant protein of donor milk obtained at different postpartum ages other than the colostrum. METHODS AND STUDY DESIGN: Donor breast milk from 12 healthy mothers was collected 15 days, 2 months and 6 months after delivery and stored by medically approved methods...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29221760/substrate-specificity-and-transfucosylation-activity-of-gh29-%C3%AE-l-fucosidases-for-enzymatic-production-of-human-milk-oligosaccharides
#7
Birgitte Zeuner, Jan Muschiol, Jesper Holck, Mateusz Lezyk, Mattias Raae Gedde, Carsten Jers, Jørn Dalgaard Mikkelsen, Anne S Meyer
Human milk oligosaccharides (HMOs) constitute a unique family of bioactive lactose-based molecules present in human breast milk. HMOs are of major importance for infant health and development but also virtually absent from bovine milk used for infant formula. Among the HMOs, the fucosylated species are the most abundant. Transfucosylation catalysed by retaining α-L-fucosidases is a new route for manufacturing biomimetic HMOs. Seven α-L-fucosidases from glycosyl hydrolase family 29 were expressed, characterized in terms of substrate specificity and thermal stability, and shown to be able to catalyse transfucosylation...
December 5, 2017: New Biotechnology
https://www.readbyqxmd.com/read/29221672/cost-and-use-of-pasteurized-donor-human-milk-at-a-children-s-hospital
#8
Diane L Spatz, Abbey C Robinson, Elizabeth B Froh
OBJECTIVE: To determine the cost and use of pasteurized donor human milk (PDHM) at a children's hospital with a strong human milk culture. DESIGN: A retrospective descriptive cohort study. SETTING: A children's hospital in the northeastern region of the United States. PARTICIPANTS: Infants (N = 281) younger than 1 year of age at the time of hospitalization who received PDHM between January 2011 and November 2014. Infants older than 1 year of age at the time of hospitalization were excluded from the study sample...
December 5, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29218832/necrotizing-enterocolitis-in-the-setting-of-milk-allergy-after-pediatric-living-donor-liver-transplantation
#9
Soichi Narumoto, Seisuke Sakamoto, Hajime Uchida, Kengo Sasaki, Takanobu Shigeta, Akinari Fukuda, Shunsuke Nosaka, Rie Irie, Takako Yoshioka, Mureo Kasahara
NEC is an idiopathic intestinal mucosal injury that may progress to transmural bowel necrosis without mesenteric ischemia. NEC usually affects 7- to 10-day-old neonates following enteral feeding. A 10-month-old girl with no history of laparotomy underwent LDLT for acute liver failure. After starting enteral feeding on postoperative day 5, she developed abdominal distention. Diffuse PVG and PI were detected by radiologic modalities. Exploratory laparotomy revealed patchy necrosis of the intestine without perforation...
December 7, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29216029/disparities-in-hospital-reported-breast-milk-use-in-neonatal-intensive-care-units-united-states-2015
#10
Ellen O Boundy, Cria G Perrine, Jennifer M Nelson, Heather C Hamner
Breast milk is the recommended nutrition for infants. For preterm infants, when mother's milk is not available, pasteurized donor milk is recommended (1). Non-Hispanic black mothers are at increased risk for having a preterm birth and for not breastfeeding (2,3); however, it is not known whether demographic disparities exist in the use of breast milk in neonatal intensive care units (NICUs). Data from CDC's 2015 Maternity Practices in Infant Nutrition and Care (mPINC) survey, which does not collect patient-level demographics, were linked to the 2011-2015 U...
December 8, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29207479/growth-and-bone-mineralization-of-very-preterm-infants-at-term-corrected-age-in-relation-to-different-nutritional-intakes-in-the-early-postnatal-period
#11
Michelle N Körnmann, Viola Christmann, Charlotte J W Gradussen, Laura Rodwell, Martin Gotthardt, Johannes B Van Goudoever, Arno F J Van Heijst
Preterm infants often have a reduced bone mineral content (BMC) with increased risk of metabolic bone disease. After birth it is difficult to supply calcium (Ca) and phosphorus (P) comparable to the high fetal accretion rate. It is not known whether high supplementation of minerals in the early postnatal period improves growth and bone mineralization. The aim of this study was to evaluate growth and bone mineralization at term corrected age (TCA) in very and extremely preterm infants who received different enteral Ca and P intakes during the first 10 days of life...
December 2, 2017: Nutrients
https://www.readbyqxmd.com/read/29198102/antimicrobial-and-antibiofilm-activity-of-human-milk-oligosaccharides-against-streptococcus-agalactiae-staphylococcus-aureus-and-acinetobacter-baumannii
#12
Dorothy L Ackerman, Kelly M Craft, Ryan S Doster, Jörn-Hendrik Weitkamp, David M Aronoff, Jennifer A Gaddy, Steven D Townsend
In a previous study, we reported that human milk oligosaccharides (HMOs) isolated from five donor milk samples possessed antimicrobial and antibiofilm activity against Streptococcus agalactiae, also known as Group B Streptococcus or GBS. Herein, we present a broader evaluation of the antimicrobial and antibiofilm activity by screening HMOs from 14 new donors against three strains of GBS and two of the ESKAPE pathogens of particular interest to child health, Staphylococcus aureus and Acinetobacter baumannii...
December 8, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/29173648/in-silico-identification-of-milk-antihypertensive-di-and-tripeptides-involved-in-angiotensin-i-converting-enzyme-inhibitory-activity
#13
Vladimir R Vukic, Dajana V Vukic, Spasenija D Milanovic, Mirela D Ilicic, Katarina G Kanuric, Mark S Johnson
Identification of bioactive milk peptides could improve food technology through improved selection of food supplements with a focus on antihypertensive properties. We hypothesized that angiotensin I-converting enzyme (ACE) inhibitory activities of milk di- and tripeptides could be predicted using 3-dimensional quantitative structure activity relationship methods and that these activities could be explained through evaluation of structural features (hydrogen bond donor/acceptor, hydrophobic, steric, and electrostatic) that are responsible for this bioactivity...
October 2017: Nutrition Research
https://www.readbyqxmd.com/read/29166382/human-milk-h2o2-content-does-it-benefit-preterm-infants
#14
Monika Cieslak, Cristina H F Ferreira, Yulia Shifrin, Jingyi Pan, Jaques Belik
BACKGROUND: Human milk has a high content of the antimicrobial compound hydrogen peroxide (H2O2). As opposed to healthy full-term infants, preterm neonates are fed previously expressed and stored maternal milk. These practices may favor H2O2 decomposition, thus limiting its potential benefit to preterm infants. The goal of this study was to evaluate the factors responsible for H2O2 generation and degradation in breastmilk. METHODS: Human donors' and rat milk, along with rat mammary tissue were evaluated...
November 22, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29166375/gastric-emptying-of-different-meal-volumes-of-identical-composition-in-preterm-infants-a-time-series-analysis
#15
Sharon L Perrella, Anna R Hepworth, Zoya Gridneva, Karen N Simmer, Peter E Hartmann, Donna T Geddes
BACKGROUND: Preterm infants' meals typically progress to higher volumes over time. Knowledge of gastric emptying (GE) responses to differing meal volumes may inform enteral feeding management. We examined the effect of meal volume and composition on preterm GE. METHODS: Forty infants were studied at 33.3±1.4 (29.7-35.6) weeks postmenstrual age when fully enteral fed (target 150 ml/kg/day). Intra-individual comparisons of GE were made for paired meals of 100 and 75% prescribed volume and identical composition of mother's own milk (n=21) and pasteurized donor human milk (n=19)...
November 22, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29161533/the-nuts-and-bolts-of-implementing-a-pasteurized-donor-human-milk-program-on-a-mother-baby-unit
#16
Sheilajane C Lewis, Marcy McMahon, Ginny Combs, Kristine Smith, Miriam Segura-Harrison, Barbara L Philipp
No abstract text is available yet for this article.
November 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29108433/the-human-milk-oligosaccharides-are-not-affected-by-pasteurization-and-freeze-drying
#17
Won-Ho Hahn, Jaehan Kim, Seunghyun Song, Suyeon Park, Nam Mi Kang
OBJECTIVES: Human milk oligosaccharides (HMOs) are known as important factors in neurologic and immunologic development of neonates. Moreover, freeze-drying seems to be a promising storage method to improve the processes of human milk banks. However, the effects of pasteurization and freeze-drying on HMOs were not evaluated yet. The purpose of this study is to analyze and compare the HMOs profiles of human milk collected before and after the pasteurization and freeze-drying. METHODS: Totally nine fresh human milk samples were collected from three healthy mothers at the first, second, and third week after delivery...
November 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29108075/polyunsaturated-fatty-acids-are-less-effective-to-reduce-methanogenesis-in-rumen-inoculum-from-calves-exposed-to-a-similar-treatment-early-in-life
#18
A Ruiz-González, S Debruyne, J Jeyanathan, L Vandaele, S De Campeneere, V Fievez
The aim of this study was to evaluate the dose response on in vitro methane (CH) production of PUFA to which the inoculum donor animals had been exposed early in life. Sixteen Holstein calves (160 ± 3 and 365 ± 2 kg BW) at 6 and 12 mo of age were used as inoculum donors. Half of the calves were given increasing amounts of extruded linseed from birth (22 g/d) until 4 mo of age (578 g/d) first mixed with milk and then included in their concentrate. Linseed oil (LSO) was supplemented in vitro at 5 different doses (0, 0...
October 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/29103706/alterations-in-ruminal-bacterial-populations-at-induction-and-recovery-from-diet-induced-milk-fat-depression-in-dairy-cows
#19
D W Pitta, N Indugu, B Vecchiarelli, D E Rico, K J Harvatine
Ten ruminally cannulated Holstein cows were used in a crossover design that investigated changes in ruminal bacterial populations in response to induction and recovery from diet-induced milk fat depression (MFD). Further, the effect on the ruminal microbiota of the cows with diet-induced milk fat depression inoculated with rumen contents from non-milk fat-depressed donor cows was evaluated. Milk fat depression was induced during the first 10 d of each period by feeding a low-fiber, high-starch, and high-polyunsaturated fatty acid diet (26...
November 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29072928/donor-milk-utilization-for-healthy-infants-experience-at-a-single-academic-center
#20
Sarbattama Sen, Charis Benjamin, Jennifer Riley, Abigail Heleba, Kaitlin Drouin, Katherine Gregory, Mandy Brown Belfort
BACKGROUND: Banked donor milk (BDM) has historically been used as an alternative to formula for preterm infants. Recently, BDM has been endorsed by two national organizations for use in healthy infants. We sought to quantify utilization trends and characteristics of mothers and their healthy newborns who received BDM during their postpartum stay between 2013 and 2016 at a single academic medical center. MATERIALS AND METHODS: In this observational study, we used a clinical log to identify all infants who received BDM in the well-baby nursery between July 2013 and June 2016...
October 26, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
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