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"low thrombocytes count"

E Forsblom, I Tielinen, E Ruotsalainen, A Järvinen
The prognostic impact of thrombocytopaenia in Staphylococcus aureus bacteraemia (SAB) has previously been determined at bacteraemia onset only and relevant pre-bacteraemic thrombocytopaenia predisposing parameters have not been accounted for. We evaluated the prognostic impact of low thrombocyte count in SAB excluding pre-bacteraemic factors potentially causing thrombocytopaenia. This was a multicentre retrospective analysis of methicillin-sensitive SAB (MS-SAB) patients. Thrombocyte count was determined at blood culture collection and at days 3 and 7...
May 2017: European Journal of Clinical Microbiology & Infectious Diseases
Yuval Glick, Elit Levin, Lisa Saidel-Odes, Francisc Schlaeffer, Klaris Riesenberg
BACKGROUND: Southern Israel is endemic for Brucella melitensis (BM) infection. AIMS: This study aims to describe clinical manifestations and laboratory abnormalities in hospitalized adults with BM-bacteremia and to assess the relationship between various laboratory parameters, outcomes and complications of brucellosis. METHODS: This is a retrospective study. All BM bacteremic patients hospitalized in the Soroka University Medical Center (SUMC) during 2006-2011 were included...
February 2016: Harefuah
Cornelis H van Werkhoven, Susanne M Huijts, Douwe F Postma, Jan Jelrik Oosterheert, Marc J M Bonten
INTRODUCTION: The diagnostic yield of blood cultures is limited in patients with community-acquired pneumonia (CAP). Yet, positive blood culture results provide important information for antibiotic treatment and for monitoring epidemiologic trends. We investigated the potential of clinical predictors to improve the cost-benefit ratio of obtaining blood cultures. METHODS: Data from two prospective cohort studies of adults with suspected CAP, admitted to non-ICU wards, were combined...
2015: PloS One
Hakan Gunes, Tarik Kivrak
Eltrombopag is a non-peptide thrombopoietin receptor agonist. Eltrombopag has originally been developed for conditions where therapy for thrombocytopenia is needed. Secondary to eltrombopag have been reported thrombotic events, chest pain, acute renal failure, neutropenia, ascites, retinal exudates, antiphospholipid syndrome. In this case, we present a 53 year-old patient who had diagnosis of Idiopathic Thrombocytopenic Purpura (ITP) for 30 years with splenectomy. He's still having low thrombocyte counts despite the classical ITP therapy...
2016: Current Drug Safety
Yavuz Simsek, Mehmet Gul, Onder Celik, Nasuhi Engin Aydin, Senem Arda Düz, Ebru Celik, Elif Ozerol, Ibrahim Halil Özerol, Kevser Tanbek
OBJECTIVE: Preeclampsia appears to be associated with a higher extent of inflammation than in uncomplicated pregnancies. We aimed to test whether this was the case in patients with hemolysis, elevated liver functions and low platelet count (HELLP) syndrome and to clarify the contribution of placental and systemic inflammatory variables in the development of this syndrome. MATERIALS AND METHODS: Thirty healthy pregnant women (control group) and 20 patients with HELLP syndrome (study group) were included in the study...
August 2013: Hypertension in Pregnancy
Roos Elisabeth Marck, Harriet Leonie Montagne, Willem Eduard Tuinebreijer, Roelf Simon Breederveld
Thrombocytopenia is common in trauma and critically ill patients and is associated with a poor outcomes. The objective of this retrospective study was to investigate the course of thrombocyte concentration changes in burn patients, the influences of various factors on this course, and a possible predictive value of thrombocyte counts on outcome in 244 patients admitted to our burn centre. Their thrombocyte counts were obtained until 50 days after burn. Data on patient demographics, total percentage burned surface area (%TBSA), sepsis and mortality were collected...
June 2013: Burns: Journal of the International Society for Burn Injuries
Erkan Parlak, Selçuk Dişibeyaz, Aydın Şeref Köksal, Bülent Odemiş, Nurgül Saşmaz, Burhan Şahin
BACKGROUND AND AIM: Endoscopic methods are effective in the control of endoscopic sphincterotomy (ES) bleeding. Initial failure or recurrent bleeding may develop in some patients, which may require angiographic or surgical interventions. We aimed to determine the factors leading to failure of endoscopic treatment methods. METHODS: Forty-six patients (1.37%) had endoscopic and/or clinically significant bleeding among a total of 3354 ESs (2998 primary, 356 re-ES) performed within 3 years...
September 2013: Clinics and Research in Hepatology and Gastroenterology
Peter Stiefelhagen
No abstract text is available yet for this article.
October 20, 2011: MMW Fortschritte der Medizin
Ovgu Ozkan Dogan, Yavuz Simsek, Sevki Celen, Nuri Danisman
AIM: The purpose of this study was to investigate the correlations between thrombophilic mutations, anticoagulant activity and hemolysis, elevated liver functions and low thrombocyte count (HELLP) syndrome. MATERIAL AND METHODS: Twenty-five healthy pregnant women (control group) and 34 patients with HELLP syndrome (study group) were included in the study between April 2007 and January 2008. Homocysteine levels and activities of protein C, protein S and antithrombin III of the groups were compared...
June 2011: Journal of Obstetrics and Gynaecology Research
Masaki Ishihara, Satoshi Kamei, Naoto Taira, Akihiko Morita, Kenji Miki, Tomoka Naganuma, Masayuki Minami, Hiroshi Shiota, Motohiko Hara, Tomohiko Mizutani
BACKGROUND: Prognostic factors related to community-acquired bacterial meningitis (BM) in adult patients have been evaluated using multivariate analysis in The Netherlands, where the rate of antibiotic resistance was low. However, an evaluation of these factors in countries with a high rate of antibiotic resistance has not yet been done. Thus, we studied the prognostic factors in adults with community-acquired BM in our hospitals, which are located in Tokyo, Japan, where the rate of antibiotic resistance is high...
2009: Internal Medicine
S M Said, J Hahn, E Schleyer, M Müller, G M Fiedler, M Buerke, R Prondzinsky
Thrombocyte glycoprotein IIb/IIIa inhibitors prevent fibrinogen binding and thereby thrombocyte aggregation. The inhibition of thrombocyte activation at the damaged coronary plaque is the target of the new therapeutic strategies in treating acute coronary syndrome. This reduces the ischemic complications associated with the non-STelevation myocardial infarction (NSTEMI) and percutaneous coronary intervention (PCI). Thrombocytopenia is a known complication of glycoprotein (GP) IIb/IIIa inhibitors. Although, in general, GP IIb/IIIa inhibitor-induced thrombocytopenia is a harmless side effect which responds readily to thrombocyte transfusion, it can occasionally be a very serious complication associated with serious bleeding...
February 2007: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Martijn Weisfelt, Diederik van de Beek, Lodewijk Spanjaard, Johannes B Reitsma, Jan de Gans
BACKGROUND: A low cerebrospinal fluid (CSF) white-blood cell count (WBC) has been identified as an independent risk factor for adverse outcome in adults with bacterial meningitis. Whereas a low CSF WBC indicates the presence of sepsis with early meningitis in patients with meningococcal infections, the relation between CSF WBC and outcome in patients with pneumococcal meningitis is not understood. METHODS: We examined the relation between CSF WBC, bacteraemia and sepsis in a prospective cohort study that included 352 episodes of pneumococcal meningitis, confirmed by CSF culture, occurring in patients aged >16 years...
2006: BMC Infectious Diseases
P O Laine, J C Lindqvist, S O Pyrhönen, L M Teerenhovi, S M Syrjänen, J H Meurman
The 1-year incidence of oral mucosal lesions during cytostatic therapy was investigated in 67 patients [34 men and 33 women (mean age 49 years)] out of 79 original patients, being treated for non-Hodgkin lymphoma or Hodgkin's disease. The incidence of lesions during examinations was 43.4%. Recurrent lesions were observed in 19.4% of cases. Mean leukocyte counts were statistically significantly lower (P < 0.01) during lesion periods than before cytostatic therapy in all lesion groups. Leukocytopenia was found in 85...
October 1993: European Journal of Cancer. Part B, Oral Oncology
R Manthorpe, B Kofod, A Wiik, O Saxtrup, S E Svehag
In a prospective 9 month study at a medical department with special interest in immunology and rheumatology, 10 patients with spuriously low thrombocyte counts - pseudothrombocytopenia - were registered. The phenomenon was observed when the counting of platelets was performed on a Thrombocounter C apparatus or by manual counting using K2EDTA stabilized blood since platelet agglutination was considerably less pronounced when solution citratis glucosi fortis (ACD) was used as the anticoagulant. Results of our in vitro studies indicate that the mechanisms contributing to pseudothrombocytopenia involve the interaction of circulating immune complexes with platelet membrane Fc receptors causing agglutination...
May 1981: Scandinavian Journal of Haematology
O J Bergmann, P L Andersen
To estimate clinical, pathogenic and serological aspects of acute oral candidiasis (AOC) during febril episodes in patients with haematologic malignancies, 23 consecutive patients who developed AOC within 7 days from start of fever were compared with 23 consecutive patients who did not develop AOC. The duration of fever and severe granulocytopenia (less than 0.5 x 10(9)/l) was significantly longer in patients with AOC than in patients without AOC, the median differences between the patients with and without AOC being 4 and 3 days, respectively...
1990: Scandinavian Journal of Infectious Diseases
E Fosse, J L Svennevig, G Semb, A Skulberg
We have studied the effect of blood-saving measures in open heart surgery. Such measures were introduced in 1987. All fluids administered on the day of operation and on the first postoperative day were registered in all cardiac patients operated during one month in 1986, 1987, 1988. In 1986 the patients were exposed to a median of 21 donors while in 1988 they were exposed to a median of 2 donors. The reduction in transfusions was achieved by substituting plasma by polygeline, by giving thrombocytes only when there was a low thrombocyte count and by accepting a hemoglobin value of 9 g/100 ml before transfusion of erythrocytes...
February 28, 1990: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
P Lautala, M Uhari
Epidemic nephropathy, a form of hemorrhagic fever with renal syndrome, caused by the Puumala serotype of hantaviruses and occurring endemically in northern Scandinavia, was studied in 13 children. The clinical symptoms and signs were somewhat different from those reported in adults; none of our patients had hemorrhagic manifestations despite low thrombocyte counts. The most common presenting symptoms were fever, abdominal pain, and renal tenderness with oliguria followed by polyuria. The predominant laboratory findings were proteinuria and/or hematuria and elevated serum creatinine levels...
October 1991: American Journal of Diseases of Children
R A Slaastad, H C Godal
In 753 consequtive blood samples (from the same number of patients) routinely examined for coagulation abnormalities, a positive ethanol gelation test was found in 160. In 7 samples with plasma fibrinogen below 150 mg/100 ml and a positive test, other laboratory signs of consumption coagulopathy (low thrombocyte count, low factor V, low antithrombin III, large amounts of FDP in serum and great discrepancies between Normotest and Thrombotest) were regularly observed. Also at normal or high fibrinogen levels, a positive ethanol gelation test was more frequently associated with low thrombocyte counts, low factor V and Normotest/Thrombotest discrepancy than was a negative test...
January 1976: Scandinavian Journal of Haematology
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