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mucinous appendiceal

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https://www.readbyqxmd.com/read/29785461/clinical-significance-of-appendiceal-diverticulum-a-significant-marker-for-appendiceal-neoplasia-in-australian-patients
#1
Daniel Leonard Chan, Christopher Lim, Arsalan Bakhtiar, Matthew Khoury, Michelle Smigelski, Dean Yeh, Praveen Ravindran
INTRODUCTION: Diverticula of the appendix (DA) have a reported incidence of up to 2.1%. They are primarily detected incidentally, through imaging and intraoperative or histologic diagnosis. This study's objective was to examine the prevalence of DA, and its relationship with inflammation and neoplasia, as well as review the literature with respect to clinical outcomes and ability to identify DA preoperatively. METHODOLOGY: A retrospective search of all patients undergoing an appendicectomy for right lower quadrant pain at a single institution between 2004 and 2017 was conducted...
May 21, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29725538/appendiceal-carcinoma-associated-with-microsatellite-instability
#2
Angélica Morales-Miranda, Ismael Domínguez Rosado, Carlos Chan Núñez, Fredy Chable Montero
Approximately 15% of colorectal cancer (CRC) cases exhibit microsatellite instability (MSI), which appears to be associated with unique biological behavior. The present study presents a case of appendiceal carcinoma associated with MSI that responded well to adjuvant chemotherapy. Clinical, pathological and immunohistochemical (IHC) characteristics have been described. The 60-year-old male patient had suffered from recurrent lower abdominal pain associated with abdominal distention for 6 months; then, following an acute attack, he was subjected to laparoscopic appendectomy...
May 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29719746/sister-mary-joseph-nodule-as-a-cutaneous-manifestation-of-metastatic-appendiceal-adenocarcinoma-case-report-and-literature-review
#3
Raghavendra L Girijala, Ryan R Riahi, Philip R Cohen
Sister Mary Joseph nodule (SMJN) is an uncommon pattern of superficial periumbilical tumor metastasis, with the primary tumor most commonly associated with gynecological or gastrointestinal origins. This manifestation can represent extensive tumor development from any of the intra-abdominal or pelvic structures. Therefore, SMJN carries a poor prognosis, with a two-year survival rate of only 13.5 percent regardless of the etiology of primary cancer. In this case, a 67-year-old man with metastatic mucinous adenocarcinoma of the appendix involving the umbilicus presenting more than five years after the initial cancer diagnosis is reported...
February 28, 2018: Curēus
https://www.readbyqxmd.com/read/29717422/management-of-mucinous-appendiceal-tumors
#4
Haroon A Choudry, Reetesh K Pai
No abstract text is available yet for this article.
May 1, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29705882/severe-peritoneal-sclerosis-after-repeated-pressurized-intraperitoneal-aerosol-chemotherapy-with-oxaliplatin-pipac-ox-report-of-two-cases-and-literature-survey
#5
M Graversen, S Detlefsen, P Pfeiffer, L Lundell, M B Mortensen
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new laparoscopic administration of chemotherapy for peritoneal metastasis (PM). PIPAC is repeated every 5th week, and seems to stabilize or improve quality of life, and might improve survival. So far, PIPAC has been well tolerated. With this paper, we aim to highlight a potential severe adverse reaction, as we describe the first cases of severe peritoneal sclerosis (SPS) caused by PIPAC. Patients with isolated PM were included in a prospective PIPAC protocol...
April 28, 2018: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/29698881/goblet-cell-carcinoid-of-the-appendix-case-report-of-a-high-grade-tumor-in-a-20-year-old
#6
Ameen Barghi, John Grabbe, Arundhati Ghosh
INTRODUCTION: Goblet cell carcinoid (GCC) is an extraordinarily rare appendiceal tumor that is usually an incidental diagnosis on post-operative histology. It typically presents in the fifth or sixth decade of life. Our patient is the only reported case study of GCC in a pediatric-young adult. Due to its potentially poor prognosis, GCC is surgically treated as an adenocarcinoma, with right hemicolectomy as the mainstay of treatment. PRESENTATION OF CASE: The patient was a 20-year-old male who presented with a history, physical exam, and work up consistent with acute appendicitis...
April 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29685759/can-low-grade-pmp-be-divided-into-prognostically-distinct-subgroups-based-on-histological-features-a-retrospective-study-and-the-importance-of-using-the-appropriate-classification
#7
Aditi Bhatt, Suniti Mishra, Robin Prabhu, Veena Ramaswamy, Antony George, Sonal Bhandare, Mita Shah, Sanket Mehta
INTRODUCTION: The pathological classification of PMP of appendiceal origin has prognostic and treatment implications. Our goals were to • Classify low grade mucinous carcinoma peritonei (LGMCP) into prognostically distinct subgroups based on histological features. • Compare the reproducibility of the WHO and the PSOGI classifications for both PMP and the appendiceal primary tumor. PATIENTS AND METHODS: A retrospective analysis of patients undergoing CRS and HIPEC or debulking surgery was done...
April 12, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29676706/-a-man-with-abdominal-pain-diarrhoea-and-rectal-bleeding
#8
A J M Oosterwijk, J W van den Berg, C C van Rossem
A 49-year-old man came to the emergency room with abdominal pain, vomiting, diarrhoea and rectal bleeding. Both colonoscopy and CT of the abdomen showed cecocolic intussusception caused by an appendiceal mucocele. An ileocecal resection was performed via a laparoscopic approach and microscopy of the tissue showed a low-grade mucinous neoplasm.
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29593930/mucinous-carcinomatosis-a-rare-association-between-an-ovarian-tumor-and-an-e-gist
#9
Hugo Palma Rios, André Goulart, Pedro Leão
Pseudomyxoma peritonei (PMP) and extragastrointestinal stromal tumors (E-GISTs) are both rare entities. Most of the time, PMP is associated with an appendiceal tumor. An ovarian mucinous tumor can mimic appendiceal metastases. E-GIST is a mesenchymal tumor that can arise from the omentum, retroperitoneum, mesentery, or pleura. We present a case of an 87-year-old woman with mucinous carcinomatosis and acute intestinal occlusion submitted to an emergency laparotomy. She has found to have a borderline mucinous tumor of the ovary from the intestinal type with several lesions of pseudomyxoma peritonei and an E-GIST from the epiploons retrocavity (intermediated risk)...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29581685/incidental-findings-in-routine-histopathological-examination-of-appendectomy-specimens-retrospective-analysis-of-1970-patients
#10
Oğuzhan Dincel, Mustafa Göksu, Bilge Aydın Türk, Burçin Pehlivanoğlu, Serap İşler
Diseases and tumors of the appendix vermiformis are very rare, except for acute appendicitis. This study aimed to examine rare findings in the histopathologic examinations of specimens of patients undergoing appendectomy due to the diagnosis of acute appendicitis. The files of 1970 patients undergoing appendectomy due to the diagnosis of acute appendicitis between March 2012 and March 2016 were retrospectively investigated. Rare findings were found in 59 (3 %) patients, and these were evaluated in detail. Patients' age, gender, pathology reports, and postoperation follow-ups were recorded...
February 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29580358/clinicopathological-features-and-management-of-appendiceal-mucoceles-a-systematic-review
#11
REVIEW
William F Morano, Elizabeth M Gleeson, Sean H Sullivan, Vennila Padmanaban, Beth L Mapow, Patricia A Shewokis, Jesus Esquivel, Wilbur B Bowne
Appendiceal mucoceles (AMs) are rare mucin-containing neoplasms with malignant potential. Lack of evidence-based data exists defining clinicopathological features for management. MEDLINE search between 1995 and 2015 was performed using search criteria "Appendix mucocele." Systematic review of patient-, pathologic-, and treatment-related characteristics was performed and data analyzed. Among 276 cases of non-perforated AMs, 163 (59%) patients were female, with variable and nonspecific presentation...
February 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29579011/histologic-and-outcome-study-supports-reclassifying-appendiceal-goblet-cell-carcinoids-as-goblet-cell-adenocarcinomas-and-grading-and-staging-similarly-to-colonic-adenocarcinomas
#12
Masato Yozu, Melanie E Johncilla, Amitabh Srivastava, David P Ryan, James C Cusack, Leona Doyle, Namrata Setia, Michelle Yang, Gregory Y Lauwers, Robert D Odze, Joseph Misdraji
Goblet cell carcinoid tumors are amphicrine tumors whose biological behavior ranges from indolent to highly aggressive, depending on tumor grade. Current grading systems for these tumors are based on identifying an adenocarcinoma arising in the setting of a goblet cell carcinoid tumor, which distinguishes this tumor from other gastrointestinal tract adenocarcinomas. Because goblet cell tumors are predominantly tumors of mucin secreting cells, we propose that they be classified as goblet cell adenocarcinomas, and graded using a methodology that has parallels in colorectal adenocarcinoma grading...
March 23, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29576463/risk-factors-for-appendiceal-and-colorectal-peritoneal-metastases
#13
Malin Enblad, Wilhelm Graf, Helgi Birgisson
BACKGROUND: Early diagnosis to target minimal volume disease has received increased attention in the management of appendiceal and colorectal peritoneal metastases (PM). This study aimed to identify risk factors for appendiceal, colon and rectal PM. METHODS: Data were retrieved from the Swedish Colorectal Cancer Registry for all patients undergoing bowel resection of appendiceal and colorectal tumours, in Sweden, 2007-2015. Risk factors for synchronous and metachronous PM were analysed with multivariate logistic and Cox proportional hazard regression models...
March 6, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29564494/mucinous-appendiceal-neoplasms-pathologic-classification-clinical-implications-imaging-spectrum-and-mimics
#14
REVIEW
Alanna Van Hooser, Todd R Williams, Daniel T Myers
Mucinous appendiceal neoplasms are uncommon, but important to recognize with imaging due to malignant potential. Peritoneal seeding and pseudomyxoma peritonei can occur with both frankly malignant as well as low-grade appendiceal neoplasms. Prospective imaging identification of potential appendiceal neoplasm is paramount to clinical/surgical management. When a mucinous appendiceal neoplasm is suspected, a right hemicolectomy with lymph node dissection is the preferred surgical management. Unfortunately, accurate preoperative diagnosis can be challenging due to a wide range of clinical presentations and overlapping imaging appearances of appendiceal neoplasms with benign entities...
March 21, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29487003/satb2-is-a-supportive-marker-for-the-differentiation-of-a-primary-mucinous-tumor-of-the-ovary-and-an-ovarian-metastasis-of-a-low-grade-appendiceal-mucinous-neoplasm-lamn-a-series-of-seven-cases
#15
Elisa Schmoeckel, Thomas Kirchner, Doris Mayr
The differentiation between a primary mucinous ovarian neoplasm and an extra-ovarian metastasis in the ovary is often challenging in the histopathologic practice. Among various ovarian metastases from the gastro-intestinal tract the low-grade appendiceal mucinous neoplasm (LAMN) is an important differential diagnosis to consider particularly in case of pseudomyxoma peritonei. A newly recognized marker in the routine diagnostic of a mucinous neoplasm in the ovary is SATB2 (Special AT-rich sequence-binding protein 2)...
March 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29483455/-a-case-of-laparoscopy-assisted-ileocecal-resection-for-large-appendiceal-mucinous-adenocarcinoma
#16
Masahiro Hashimoto, Kohei Murata, Yoshinori Kagawa, Atsushi Naito, Kenji Kawai, Takuya Sakamoto, Kohei Murakami, Yoshiteru Katsura, Akihisa Omura, Toru Masuzawa, Atsushi Takeno, Michiko Yoshimura, Yutaka Takeda, Takeshi Kato, Shigeyuki Tamura
Appendiceal mucinous adenocarcinoma accompanied by cysts ruptures by surgical operation and leakage of mucus into the peritoneal cavity results in deterioration of prognosis.We report a case where the appendix mucinous adenocarcinoma was safely excised by laparoscopically preceding vascular treatment, lymph node dissection and intestinal dissection.The case was a woman in her forty-age suffering from the right lower quadrant and fever; no improvement was observed even when antibiotics were administered.A cystic lesion with a maximum diameter of 75mm was found on the right side of the pelvis with CT, and numerous lymph adenopathy was observed along the iliac artery...
February 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29428475/peritoneal-metastases-invading-the-seminal-vesicles-radiologic-appearance-and-outcome-of-treatment
#17
Paul H Sugarbaker
BACKGROUND: Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) may be of greatest benefit if all visible evidence of disease is resected. In some male patients the peritoneal metastases within the pelvis are invasive into the seminal vesicles and complete cytoreduction requires resection of these structures. PATIENTS AND METHODS: From a prospective database of colorectal and appendiceal cancer patients who had CT evidence of seminal vesicle involvement and then had cytoreduction including resection of the seminal vesicles were reviewed...
January 12, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29394656/-a-case-of-appendiceal-mucinous-adenocarcinoma-detected-with-a-bladder-tumor
#18
Shinji Tsutsumi, Akihiko Murata, Yoichi Yamauchi, Kensuke Okano, Hiroshi Yokoyama, Akitoshi Kimura, Yoshiya Ishizawa, Minoru Umehara, Masashi Kato, Naoki Hashimoto, Yutaka Umehara, Shinsuke Nishikawa, Kenichi Takahashi, Takayuki Morita
A 74-year-oldwoman hadconsultedthe department of urology in our hospital because of microscopic hematuria. Cystoscopy revealeda urinary bladder tumor, suspectedas an adenocarcinoma basedon biopsy. MRI showeda cystic tumor of the appendix with vesical fistula; therefore, she underwent an operation with a diagnosis of appendiceal cancer invading the urinary bladder. During the operation, we found that the appendix sunk into the urinary bladder with right adnexa. Therefore, we performed ileocecal resection, partial resection of the urinary bladder, and right adnexectomy...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29352970/an-uncommon-cecal-bulge-caused-by-a-large-appendiceal-mucinous-neoplasm
#19
Michael Xiang Ma, Jee Kong, Simon Hillery, Kim Cheah
No abstract text is available yet for this article.
January 17, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29352430/correction-to-clinical-surveillance-after-macroscopically-complete-surgery-for-low-grade-appendiceal-mucinous-neoplasms-lamn-with-or-without-limited-peritoneal-spread-long-term-results-in-a-prospective-series
#20
Marcello Guaglio, Snita Sinukumar, Shigeki Kusamura, Massimo Milione, Filippo Pietrantonio, Luigi Battaglia, Stefano Guadagni, Dario Baratti, Marcello Deraco
In the original article Massimo Milione's last name was spelled incorrectly. It is correct as reflected here. The original article has also been updated.
January 19, 2018: Annals of Surgical Oncology
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