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Obesity management

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https://www.readbyqxmd.com/read/29908352/man1b-cdg-novel-variants-with-a-distinct-phenotype-and-review-of-literature
#1
Meena Balasubramanian, Diana S Johnson
BACKGROUND: Congenital disorders of glycosylation (CDG) are a group of rare metabolic diseases due to impaired lipid and protein glycosylation. It comprises a characteristic high frequency of intellectual disability (ID) and a wide range of clinical phenotypes. OBJECTIVE: (s): To identify the underlying diagnosis in two families each with two siblings with variable level of ID through trio whole exome sequencing. METHODS: Both the families were recruited to the Deciphering Developmental Disorders (DDD) study to identify the aetiology for their ID...
June 13, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29908054/a-randomized-controlled-feasibility-trial-in-behavioral-weight-management-for-underserved-postpartum-african-american-women-the-renew-study
#2
Priya P Joshi, Lisa M Quintiliani, Ashley C McCarthy, Ashley Gilmore, Mufaddal Mahesri, Lisa M Sullivan, Caroline M Apovian
We aimed to test the feasibility of an in-person behavioral weight-loss intervention for underserved postpartum African American women with overweight or obesity in an urban hospital setting. Participants were randomized to an intervention of a culturally tailored adaptation of the Diabetes Prevention Program or usual care. The primary outcome was program satisfaction. Women who completed the intervention reported higher levels of satisfaction with the program, despite low attendance rates at group meetings...
June 14, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29907091/end-stage-renal-disease-treated-in-provence-alpes-c%C3%A3-te-d-azur-12-years-follow-up-and-forecast-to-the-year-2030
#3
Anne-Claire Durand, Elisabeth Jouve, Jean-Christophe Delarozière, Mohamed Boucekine, Ghizlane Izaaryene, Adeline Crémades, Franck Mazoué, Bénédicte Devictor, Asmatullah Kakar, Roland Sambuc, Philippe Brunet, Stéphanie Gentile
BACKGROUND: This study describes the time trend of renal replacement therapy for end-stage renal disease (ESRD) in the Provence-Alpes Côte d'Azur region (PACA) between 2004 and 2015, and forecasts up to 2030. METHODS: A longitudinal study was conducted on all ESRD patients treated in PACA and recorded in the French Renal Epidemiology and Information Network (REIN) during this period. Time trends and forecasts to 2030 were analyzed using Poisson regression models...
June 15, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29907086/potential-risk-factors-and-prevalence-of-helicobacter-pylori-infection-among-adult-patients-with-dyspepsia-symptoms-in-cameroon
#4
Laure Brigitte Kouitcheu Mabeku, Michelle Larissa Noundjeu Ngamga, Hubert Leundji
BACKGROUND: Helicobacter pylori is a Gram negative bacterium that colonizes the stomach of approximately two-thirds of the human population and it is involved in the pathogenesis of gastroduodenal diseases. This study sought to determine potential risk factors associated with seroprevalence of H. pylori among dyspepsia patients in Cameroon for a better management of the disease. METHODS: The study was carried out from August to December 2014 at Laquintinie Hospital and District Hospital of Bonassama in Douala metropolis...
June 15, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29904577/surgical-treatment-of-obesity
#5
REVIEW
Vance L Albaugh, Naji N Abumrad
Obesity prevalence continues to increase worldwide, as do the numerous chronic diseases associated with obesity, including diabetes, non-alcoholic fatty liver disease, dyslipidemia, and hypertension. The prevalence of bariatric surgery also continues to increase and remains the most effective and sustainable treatment for obesity. Over the last several years, numerous prospective and longitudinal studies have demonstrated the benefits of bariatric surgery on weight loss, mortality, and other chronic diseases...
2018: F1000Research
https://www.readbyqxmd.com/read/29903687/adolescents-experiences-of-obesity-surgery-a-qualitative-study
#6
Karin Nordin, Anna-Lena Brorsson, Kerstin Ekbom
BACKGROUND: The positive effects of behavioural treatment and weight management in adolescents with severe obesity are modest. Obesity surgery can be an option for adolescents, but is not the first-hand choice of treatment. The knowledge about adolescents' own experiences of having undergone surgery and their thoughts and feelings of the follow-up period are limited. OBJECTIVES: To describe adolescents' decision to go through obesity surgery as teenager and their experiences of the follow-up period...
April 26, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29902214/body-weight-perception-disordered-weight-control-behaviors-and-depressive-symptoms-among-korean-adults-the-korea-national-health-and-nutrition-examination-survey-2014
#7
Yongjoo Kim, S Bryn Austin, S V Subramanian, Ichiro Kawachi
BACKGROUND/ PURPOSE: Despite emerging evidence suggesting harmful influences of accurate weight perception on psychological health among individuals with obesity, little is known about the association in Asian populations. The aim of this study was investigate the association between body weight perception and depressive symptoms among Korean adults, and potential differential associations across gender. METHODS: We used data from the sixth Korea National Health and Nutrition Examination Survey in 2014, comprising 3,318 female (n = 1,876) and male (n = 1,442) participants, aged 19-65 years, with no history of depression and a body-mass index (BMI)> = 18...
2018: PloS One
https://www.readbyqxmd.com/read/29901549/a-bibliometric-analysis-of-clinical-and-translational-research-in-pediatric-gastroenterology-from-1970-to-2017
#8
Melanie H Schwimmer, Mary Catherine Sawh, Karen M Heskett, Nidhi P Goyal, Kimberly P Newton, Jeffrey B Schwimmer
OBJECTIVES: Pediatric gastroenterology is a clinical and research discipline principally developed over the past 50 years. Bibliometric methods provide quantitative analysis and identify research trends. Study aims were to characterize the growth and trends in pediatric gastroenterology clinical and translational research using citation analysis. METHODS: Using citations analysis software, a search strategy specific for pediatric gastroenterology was implemented for the years 1970-2017...
June 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29900680/guided-self-help-to-manage-binge-eating-in-a-dietetic-led-community-weight-management-service
#9
G D Traviss-Turner, U Philpot, J Wilton, K Green, S Heywood-Everett, A J Hill
An estimated 30% of patients accessing community weight management services experience symptoms of binge eating disorder (BED). Guided self-help (GSH) is the recommended first line of treatment for BED. This study is a preliminary investigation into the effectiveness of GSH delivered by dietitians for patients with binge eating within a weight management service and a consideration of the association between wellbeing, therapeutic relationship and outcomes. The study was conducted as a single group, pre- and post-intervention study with 24 patients reporting symptoms of binge eating who completed the self-help manual with guidance from a trained community dietitian...
June 14, 2018: Clinical Obesity
https://www.readbyqxmd.com/read/29900417/the-tatton-brown-rahman-syndrome-a-clinical-study-of-55-individuals-with-de-novo-constitutive-dnmt3a-variants
#10
Katrina Tatton-Brown, Anna Zachariou, Chey Loveday, Anthony Renwick, Shazia Mahamdallie, Lise Aksglaede, Diana Baralle, Daniela Barge-Schaapveld, Moira Blyth, Mieke Bouma, Jeroen Breckpot, Beau Crabb, Tabib Dabir, Valerie Cormier-Daire, Christine Fauth, Richard Fisher, Blanca Gener, David Goudie, Tessa Homfray, Matthew Hunter, Agnete Jorgensen, Sarina G Kant, Cathy Kirally-Borri, David Koolen, Ajith Kumar, Anatalia Labilloy, Melissa Lees, Carlo Marcelis, Catherine Mercer, Cyril Mignot, Kathryn Miller, Katherine Neas, Ruth Newbury-Ecob, Daniela T Pilz, Renata Posmyk, Carlos Prada, Keri Ramsey, Linda M Randolph, Angelo Selicorni, Deborah Shears, Mohnish Suri, I Karen Temple, Peter Turnpenny, Lionel Val Maldergem, Vinod Varghese, Hermine E Veenstra-Knol, Naomi Yachelevich, Laura Yates, Nazneen Rahman
Tatton-Brown-Rahman syndrome (TBRS; OMIM 615879), also known as the DNMT3A-overgrowth syndrome, is an overgrowth intellectual disability syndrome first described in 2014 with a report of 13 individuals with constitutive heterozygous DNMT3A variants. Here we have undertaken a detailed clinical study of 55 individuals with de novo DNMT3A variants, including the 13 previously reported individuals. An intellectual disability and overgrowth were reported in >80% of individuals with TBRS and were designated major clinical associations...
2018: Wellcome Open Research
https://www.readbyqxmd.com/read/29898885/making-progress-on-the-global-crisis-of-obesity-and-weight-management
#11
Michael E J Lean, Arne Astrup, Susan B Roberts
No abstract text is available yet for this article.
June 13, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29898382/effect-of-long-term-nitrite-administration-on-browning-of-white-adipose-tissue-in-type-2-diabetic-rats-a-stereological-study
#12
Tarlan Varzandi, Mahammad Amin Abdollahifar, Seyed Ali Haeri Rohani, Abbas Piryaei, Azita Zadeh-Vakili, Sajad Jeddi, Asghar Ghasemi
INTRODUCTION: Nitric oxide (NO) deficiency is associated with obesity and type 2 diabetes. Nitrite, a NO donor, is considered as a new therapeutic agent in diabetes. This study aims at determining effects of long-term nitrite administration on browning of white adipose tissue (WAT) in type 2 diabetic rats. METHODS: Male rats were divided into 4 groups: Control, control + nitrite, diabetes, and diabetes + nitrite. Sodium nitrite (50 mg/L in drinking water) was administered for 3 months...
June 10, 2018: Life Sciences
https://www.readbyqxmd.com/read/29898234/identifying-and-preventing-eating-disorders-in-adolescent-patients-with-obesity
#13
Sharonda Alston Taylor, Sarah Ditch, Shana Hansen
Adolescents with obesity are not immune to developing disordered eating and eating disorders. They most commonly present with atypical or subthreshold criterion due to excess body weight or questions regarding the presence of a distorted body image. Patients with premorbid overweight/obesity and subsequent achievement of weight loss may lead to delays in the recognition and treatment of disordered eating and eating disorders. In fact, disordered eating and eating disorders tend to be higher in those undergoing weight management...
June 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29897305/reducing-the-prevalence-of-obesity-in-canada-a-call-to-action
#14
Rachel Shentow-Bewsh, Daniyal Zuberi
With rates of obesity among adults and youth rising in Canada, it is clear that the current approaches currently used to reduce the prevalence of obesity, with an emphasis on individual weight management interventions focused on restrictive dieting, are not proving successful at a population level. Given that obesity is associated with poor physical and mental health outcomes, is placing a multi-billion-dollar economic burden on Canada and disproportionately affects disadvantaged groups, such as Aboriginal Canadians and women of low socioeconomic status, it is a health and social issue that must be addressed immediately by social workers and policy makers...
June 13, 2018: Social Work in Public Health
https://www.readbyqxmd.com/read/29895848/vitamin-a-and-micronutrient-deficiencies-post-bariatric-surgery-aetiology-complications-and-management-in-a-complex-multiparous-pregnancy
#15
Fiona L Mackie, Nicola S Cooper, Louise J Whitticase, Amanda Smith, William L Martin, Sheldon C Cooper
Adequate vitamin A is essential for healthy pregnancy, but high levels may be teratogenic. We present a patient who underwent bariatric surgery, prior to child bearing, and suffered maternal and foetal complications during eleven pregnancies, possibly associated with vitamin A deficiency, amongst multiple micronutrient deficiencies and risk factors including smoking and obesity. Maternal complications included visual disturbance, night blindness and recurrent infections. Recurrent foetal pulmonary hypoplasia and microphthalmia led to foetal and neonatal loss, not previously described in the medical literature...
June 12, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29895427/management-of-gastric-fistula-complicating-laparoscopic-sleeve-gastrectomy-with-biological-glue-in-a-combined-percutaneous-and-endoscopic-approach
#16
Ahmad Assalia, Anat Ilivitzki, Amos Ofer, Alain Suissa, Elias Manassa, Ahmad Mahajna, Iyad Khamaysi
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is considered as a first line treatment for morbid obesity around the globe. Leakage and subsequent gastric fistula is the most dreadful complication, which may lead to serious morbidity and even mortality. OBJECTIVES: To assess the safety and efficacy of fibrin glue application in the setting of gastric fistula after LSG. SETTING: University hospital, Israel. METHODS: Twenty-four morbidly obese patients (mean age = 42...
April 22, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29892993/pre-pregnancy-weight-loss-in-women-with-obesity-requesting-removal-of-their-intra-uterine-contraceptive-device-in-order-to-conceive-a-pilot-study-of-full-meal-replacement
#17
L Brackenridge, N Finer, R L Batterham, K Pedram, T Ding, J Stephenson, J Barry, P Hardiman
Obesity during pregnancy is associated with increased risks of thromboembolism, gestational diabetes, pre-eclampsia, miscarriage, congenital anomaly, macrosomia and stillbirth. The current practice, directed at reducing gestational weight gain, is largely ineffective. The present pilot study was designed to assess the acceptability of a 24-week intensive weight management programme (IWMP; full meal replacement followed by partial meal replacement and weight stabilization) to achieve weight loss for women with obesity requesting removal of their intra-uterine contraceptive device in order to conceive...
June 11, 2018: Clinical Obesity
https://www.readbyqxmd.com/read/29892570/management-of-gastroesophageal-reflux-disease-in-adults-a-pharmacist-s-perspective
#18
REVIEW
Brett MacFarlane
Gastroesophageal reflux disease (GERD) is a common gastrointestinal diagnosis, a leading reason for endoscopy and cause of potentially serious complications, resulting in significant individual and system-wide health burden. Approximately one quarter of people living in western countries have experienced GERD, and the prevalence appears to be on the rise. Risk factors for GERD include hiatus hernia, obesity, high-fat diet, tobacco smoking, alcohol consumption, pregnancy, genetics, and some medications. The cardinal symptoms of GERD are troublesome heartburn and regurgitation...
2018: Integrated Pharmacy Research and Practice
https://www.readbyqxmd.com/read/29890171/weight-loss-strategies-for-treatment-of-obesity-lifestyle-management-and-pharmacotherapy
#19
REVIEW
Robert F Kushner
Obesity is one of the most serious and prevalent non-communicable diseases of the twenty-first century. It is also a patient-centered condition in which affected individuals seek treatment through a variety of commercial, medical and surgical approaches. Considering obesity as a chronic medical disease state helps to frame the concept of using a three-stepped intensification of care approach to weight management. As a foundation, all patients should be counseled on evidence-based lifestyle approaches that include diet, physical activity and behavior change therapies...
June 8, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29889580/a-pilot-test-of-the-gowoman-weight-management-intervention-for-women-with-mobility-impairments-in-the-online-virtual-world-of-second-life-%C3%A2
#20
Margaret A Nosek, Susan Robinson-Whelen, Tracey A Ledoux, Rosemary B Hughes, Daniel P O'Connor, Rebecca E Lee, Rebecca Goe, Stephanie L Silveira, Rachel Markley, Thomas M Nosek
OBJECTIVE: Pilot test GoWoman, a small-group weight management intervention for mobility impaired women that was a disability- and gender-responsive adaptation of the Diabetes Prevention Program delivered in the online virtual world of Second Life® . Objectives were to (1) examine pre-/post-intervention differences in weight, waist circumference, diet, physical activity, self-efficacy for diet and physical activity, nutrition knowledge and social support for weight management, (2) determine intervention feasibility (fidelity, attrition, engagement, acceptability)...
June 11, 2018: Disability and Rehabilitation
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