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pregnancy endocrinology

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https://www.readbyqxmd.com/read/28292614/embryo-transfer-simulation-improves-pregnancy-rates-and-decreases-time-to-proficiency-in-reproductive-endocrinology-and-infertility-fellow-embryo-transfers
#1
Ryan J Heitmann, Micah J Hill, John M Csokmay, Justin Pilgrim, Alan H DeCherney, Shad Deering
OBJECTIVE: To design and evaluate an ET simulator to train Reproductive Endocrinology and Infertility (REI) fellows' techniques of ET. DESIGN: Simulation model development and retrospective cohort analysis. SETTING: Not applicable. PATIENT(S): Patients undergoing IVF. INTERVENTION(S): Simulation model evaluation and implementation of ET simulation training. MAIN OUTCOME MEASURE(S): Pregnancy rates...
March 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28276192/the-pregnancy-outcome-of-progesterone-primed-ovarian-stimulation-using-medroxyprogesterone-acetate4mg-versus-10mg-daily-in-infertile-women-undergoing-in-vitro-fertilization-a-randomized-controlled-trial
#2
J Dong, Y Wang, W R Chai, Q Q Hong, N L Wang, L H Sun, H Long, L Wang, H Tian, Q F Lyu, X F Lu, Q J Chen, Y P Kuang
OBJECTIVE: To investigate the clinical outcome and endocrinological characteristics of progestin-primed ovarian stimulation (PPOS) using medroxyprogesterone acetate (MPA) 4mg versus 10mg daily in infertile women with normal ovary reserve. DESIGN: A randomized parallel controlled trial. SETTING: Tertiary-care academic medical center. PARTICIPANTS: 300 infertile women undergoing IVF/ICSI treatment. METHODS: HMG 225IU/d and MPA (group A: 10mg/d; group B: 4mg/d) were started simultaneously from cycle day 3 onwards...
March 9, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28228319/optimizing-natural-fertility-a%C3%A2-committee-opinion
#3
(no author information available yet)
This Committee Opinion provides practitioners with suggestions for optimizing the likelihood of achieving pregnancy in couples/individuals attempting conception who have no evidence of infertility. This document replaces the document of the same name previously published in 2013, Fertil Steril 2013;100(3):631-7.
January 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28217518/a-2016-clinical-practice-pattern-in-the-management-of-primary-hypothyroidism-among-doctors-from-different-clinical-specialties-in-new-delhi
#4
Vineet Surana, Sameer Aggarwal, Deepak Khandelwal, Rajiv Singla, Saptarshi Bhattacharya, Sachin Chittawar, Sanjay Kalra, Deep Dutta
BACKGROUND: This study aimed to document practices in managing hypothyroidism among doctors in New Delhi, with special focus on subclinical hypothyroidism, pregnancy, and old age, and to compare it with global practices. METHODS: During an academic program attended by 394 doctors, all participants were given a questionnaire designed based on thyroid practices survey done by Burch et al. to evaluate the practice patterns. Questions were based on evaluating doctor's preferred choices in diagnosis, therapy, and follow-up of hypothyroidism in different scenarios...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28176826/annexin-a5-organized-in-2d-network-at-the-plasmalemma-eases-human-trophoblast-fusion
#5
Severine A Degrelle, Pascale Gerbaud, Ludovic Leconte, Fatima Ferreira, Guillaume Pidoux
Only a limited number of human cells can fuse to form a multinucleated syncytium. Cell fusion occurs as part of the differentiation of some cell types, including myotubes in muscle and osteoclasts in remodeling bone. In the differentiation of the human placenta, mononuclear cytotrophoblasts aggregate and fuse to form endocrinologically active, non-proliferative, multinucleated syncytia. These syncytia allow the exchange of nutrients and gases between the maternal and fetal circulation. Alteration of syncytial formation during pregnancy affects fetal growth and the outcome of the pregnancy...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28162192/-the-454th-case-a-29-week-pregnant-woman-with-abdominal-pain-hyperlipemia-and-multiorgan-dysfunction
#6
D Wu, J Xu, J M Peng, L K Ma, S Chen, X G Li, T P Zhang, J M Qian
A 32 year-old woman in the third trimester of pregnancy was admitted for severe acute pancreatitis due to hypertriglyceridemia. During hospitalization she developed multiorgan dysfunction, infected pancreatic necrosis, abdominal compartment syndrome and intrauterine fetal death. She was successfully treated by multidisciplinary team including department of emergency medicine, ICU, gastroenterology, obstetrics, endocrinology, ultrasonography, radiology, infectious disease, nutrition and surgery.
February 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28012859/endogenous-opiates-and-behavior-2015
#7
REVIEW
Richard J Bodnar
This paper is the thirty-eighth consecutive installment of the annual review of research concerning the endogenous opioid system. It summarizes papers published during 2015 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides, opioid receptors, opioid agonists and opioid antagonists. The particular topics that continue to be covered include the molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors related to behavior, and the roles of these opioid peptides and receptors in pain and analgesia, stress and social status, tolerance and dependence, learning and memory, eating and drinking, drug abuse and alcohol, sexual activity and hormones, pregnancy, development and endocrinology, mental illness and mood, seizures and neurologic disorders, electrical-related activity and neurophysiology, general activity and locomotion, gastrointestinal, renal and hepatic functions, cardiovascular responses, respiration and thermoregulation, and immunological responses...
February 2017: Peptides
https://www.readbyqxmd.com/read/27994298/relationship-between-genotype-variants-follicle-stimulating-hormone-receptor-gene-polymorphisms-fshr-and-morphology-of-oocytes-prior-to-icsi-procedures
#8
Zafer Gashi, Shkelzen Elezaj, Afrim Zeqiraj, Driton Grabanica, Isak Shabani, Bujar Gruda, Fitore Gashi
INTRODUCTION: This study investigated association of Asn680Ser FSHR polymorphism with the ovarian response in 104 women of Albanian ethnic population enrolled in ICSI program. The reason of infertility in all cases has been identified as male factor. METHODS: Analysis of the Asn680Ser polymorphism was performed using TaqMan(®) SNP Genotyping Assay. Clinical and endocrinologic parameters were analyzed based on the genotype, age, BMI, oocyte yield, number of transferred embryos and pregnancy rate...
October 2016: Medical Archives
https://www.readbyqxmd.com/read/27882768/-adrenocortical-oncocytoma-presenting-as-cushing%C3%A2-s-syndrome-in-pregnancy-with-spontaneous-postpartum-uterine-rupture
#9
M Kotoulová, I Mikysková, J Dušková, J Vláčil, M Dvořák, M Halaška
OBJECTIVE: The description of rare case of the Cushings syndrome in pregnancy resulting in the spontaneous rupture of uterus. DESIGNS: A case report. SETTING: Department of Gynecology and Obstetrics, 1st Medical Faculty of Charles University and Hospital Na Bulovce. CASE REPORT: The authors report the case of a 33 year old woman, who was admitted to the clinic in 30th week of pregnancy for elevated blood pressure and hypokalemia...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27843806/a-2016-italian-survey-about-the-clinical-use-of-selenium-in-thyroid-disease
#10
Roberto Negro, Roberto Attanasio, Franco Grimaldi, Claudio Marcocci, Rinaldo Guglielmi, Enrico Papini
BACKGROUND: Selenium (Se) is a trace element that plays key roles in thyroid physiology. Se deficiency is associated with increased risk of thyroid disease. Some evidence suggests that Se supplementation may be beneficial in autoimmune thyroid disease (either hypo- or hyperthyroidism). OBJECTIVES: We sought to examine the use of Se in daily clinical practice among Italian endocrinologists. METHODS: Members of the Associazione Medici Endocrinologi (AME) were invited to participate in a web-based survey investigating the use of Se in different clinical conditions...
September 2016: European Thyroid Journal
https://www.readbyqxmd.com/read/27779622/mothers-do-it-differently-reproductive-experience-alters-fear-extinction-in-female-rats-and-women
#11
J S Milligan-Saville, B M Graham
Fear extinction is the laboratory basis of exposure therapy for anxiety disorders. Recent findings have revealed that estradiol is necessary to the consolidation of extinction memories in females. These findings are based on studies conducted using virgin rats and young women whose reproductive history is unknown. We hypothesized that motherhood, which results in extensive endocrinological, neurobiological and behavioral changes, may lead to alterations in fear extinction in females. We used a cross-species translational approach to investigate the impact of reproductive experience on fear extinction and fear relapse in female rats (n=116) and women (n=64)...
October 25, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27743688/puberty-ovarian-cycle-pregnancy-and-postpartum-ovulation-in-captive-sichuan-golden-monkeys-rhinopithecus-roxellana-based-on-changes-in-urinary-and-fecal-gonadal-steroid-metabolites
#12
Muren, Satoshi Kusuda, Osamu Doi, Hitomi Naito, Hisashi Hashikawa
The purpose of this study was to evaluate the reproductive status and clarify the reproductive physiology of captive Sichuan golden monkeys. The concentrations of urinary estradiol-3-glucuronide (E2G) and pregnanediol-glucuronide (PdG) or fecal estradiol-17β (E2) and PdG in two females, and fecal testosterone concentrations in a male, were measured continuously using enzyme immunoassays. On the basis of these hormone profiles, the follicular phase, luteal phase, and ovarian cycle were calculated to be 14.7 ± 4...
January 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/27736313/hormonal-replacement-in-hypopituitarism-in-adults-an-endocrine-society-clinical-practice-guideline
#13
Maria Fleseriu, Ibrahim A Hashim, Niki Karavitaki, Shlomo Melmed, M Hassan Murad, Roberto Salvatori, Mary H Samuels
OBJECTIVE: To formulate clinical practice guidelines for hormonal replacement in hypopituitarism in adults. PARTICIPANTS: The participants include an Endocrine Society-appointed Task Force of six experts, a methodologist, and a medical writer. The American Association for Clinical Chemistry, the Pituitary Society, and the European Society of Endocrinology co-sponsored this guideline. EVIDENCE: The Task Force developed this evidence-based guideline using the Grading of Recommendations, Assessment, Development, and Evaluation system to describe the strength of recommendations and the quality of evidence...
November 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27734685/-iodine-supply-of-pregnant-women-in-the-czech-republic
#14
Radovan Bílek, Nataša Kaňová, Veronika Mindžáková, David Neumann, Jan Jiskra, Lydie Ryšavá, Václav Zamrazil
INTRODUCTION: Iodine deficiency is a global public health problem which is particularly noticeable in pregnant or breastfeeding women and their children. Even mild iodine deficiency during pregnancy can lead to damage to the developing brain and thus affecting the fetus intelligence, his cognitive and neurological function, embryogenesis and growth. PATIENTS: In the period 2010-2015 was determined by spectrophotometry at the Institute of Endocrinology the basal urinary iodine in 532 pregnant women at the age of 32 ± 5 (18-44) years, which came from Prague, Hradec Kralove and Mlada Boleslav...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27731904/chinese-herbal-medicine-for-subfertile-women-with-polycystic-ovarian-syndrome
#15
REVIEW
Kunyan Zhou, Jing Zhang, Liangzhi Xu, Taixiang Wu, Chi Eung Danforn Lim
BACKGROUND: Polycystic ovarian syndrome (PCOS) is one of the most common reproductive endocrinology abnormalities, and affects 5% to 10% of women of reproductive age. Western medicines, such as oral contraceptives, insulin sensitizers and laparoscopic ovarian drilling (LOD), have been used to treat PCOS. Recently, many studies have been published that consider Chinese herbal medicine (CHM) as an alternative treatment for women with PCOS. OBJECTIVES: To assess the efficacy and safety of CHM for subfertile women with PCOS...
October 12, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27729465/vascular-adaptation-in-pregnancy-and-endothelial-dysfunction-in-preeclampsia
#16
REVIEW
D S Boeldt, I M Bird
Maternal vascular adaptation to pregnancy is critically important to expand the capacity for blood flow through the uteroplacental unit to meet the needs of the developing fetus. Failure of the maternal vasculature to properly adapt can result in hypertensive disorders of pregnancy such as preeclampsia (PE). Herein, we review the endocrinology of maternal adaptation to pregnancy and contrast this with that of PE. Our focus is specifically on those hormones that directly influence endothelial cell function and dysfunction, as endothelial cell dysfunction is a hallmark of PE...
January 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/27651724/a-novel-approach-using-a-minimal-number-of-injections-during-the-ivf-icsi-cycle-luteal-half-dose-depot-gnrh-agonist-following-corifollitropin-alfa-versus-the-corifollitropin-alfa-with-a-gnrh-antagonist-cycle
#17
Bülent Haydardedeoğlu, Esra Bulgan Kılıçdağ
OBJECTIVE: Corifollitropin alfa is a good choice for assisted reproductive technology (ART) cycles because fewer injections are needed than with other agents. In this retrospective cohort, we analyzed luteal injected half-dose depot gonadotropin hormone-releasing hormone (GnRH) agonist cycles in women who received corifollitropin alfa and those who underwent a conventional corifollitropin alfa cycle with a GnRH antagonist. MATERIAL AND METHODS: In this retrospective cohort, we analyzed luteal injected half-dose depot GnRH agonist cycles in women who received corifollitropin alfa and those who underwent a conventional corifollitropin alfa cycle with a GnRH antagonist at the Division of Reproductive Endocrinology and IVF Unit, Obstetrics and Gynecology Department, Başkent University School of Medicine, Adana, Turkey, from March 2014 to August 2015...
2016: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/27631591/autologous-transplantation-of-cryopreserved-ovarian-tissue-to-induce-puberty-the-endocrinologists-view
#18
Michael von Wolff, Petra Stute, Christa Flück
Transplantation of cryopreserved ovarian tissue has been shown to successfully induce pregnancies. Furthermore, puberty may be induced by transplanted ovarian tissue in girls suffering from premature primary ovarian insufficiency (PPOI) due to gonadotoxic therapy. Therefore, the question arises if ovarian tissue cryopreservation should be recommended for puberty induction in prepubertal girls with cancer prior to gonadotoxic therapies. Although this strategy seems to be more natural than administering exogenous steroid sex hormones, there are some disadvantages from the endocrinological point of view...
December 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27593922/benign-prostatic-hyperplasia-case-report-of-a-17-year-old
#19
Ismail Yağmur, Burak Turna, Ali Tekin, Emir Akıncıoğlu, Bnu Sarsık, İbrahim Ulman
INTRODUCTION: Benign prostatic hyperplasia (BPH) is generally common in men older than 50 years of age but is extremely rare in childhood. In the literature to date, fewer than five cases have been reported under 18 years of age. Owing to the limited number of cases, the etiology and management of BPH in the first two decades is not clear. OBJECTIVE: We herein report a 17-year-old boy who presented with acute urinary retention due to BPH and was treated with endoscopic transurethral resection of the prostate (TUR-P)...
August 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27531964/variation-in-the-use-of-definitive-treatment-options-in-the-management-of-graves-disease-a-uk-clinician-survey
#20
Jessica Hookham, Emma E Collins, Amit Allahabadia, Sabapathy P Balasubramanian
BACKGROUND: Graves' disease can be treated with antithyroid drugs (ATDs), radioiodine or surgery. Use of definitive treatments (radioiodine or surgery) varies widely across centres. Specific clinical circumstances, local facilities, patient and clinician preferences and perceptions will affect the choice of treatment. Detailed understanding of UK clinicians' views and their rationale for different treatments is lacking. AIMS: To study the preferences and perceptions of UK clinicians on the role of surgery and radioiodine in the management of Graves' disease...
April 2017: Postgraduate Medical Journal
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