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pregnancy endocrinology

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https://www.readbyqxmd.com/read/29445919/appraisal-of-clinical-practice-guidelines-on-the-management-of-hypothyroidism-in-pregnancy-using-the-appraisal-of-guidelines-for-research-and-evaluation-ii-instrument
#1
REVIEW
Yuan Fang, Liang Yao, Jing Sun, Jian Zhang, Yanxia Li, Ruifei Yang, Kehu Yang, Limin Tian
PURPOSE: This study aimed to systematically evaluate the quality of guidelines for the management of hypothyroidism in pregnancy. METHOD: Systematic searches were conducted to identify hypothyroidism in pregnancy guidelines published in electronic databases and developers' websites. Four reviewers independently evaluated eligible guidelines using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument. Agreement among reviewers was measured using the intraclass correlation coefficient (ICC)...
February 14, 2018: Endocrine
https://www.readbyqxmd.com/read/29423789/do-trained-reproductive-endocrinologists-perform-better-than-their-trainees-comparing-clinical-pregnancy-rates-and-live-birth-rates-after-transfer-of-single-fresh-blastocysts
#2
Sadikah Behbehani, Joseph Hasson, Stefano Polesello, W Y Son, Togas Tulandi, William Buckett
PURPOSE: To compare clinical pregnancy rates and live birth rates of single blastocyst transfers performed by attending physicians or fellows in reproductive endocrinology and infertility program. METHODS: Retrospective study in an academic reproductive center. We evaluated 932 fresh single blastocyst transfer cycles performed by fellows in training (389 embryo transfers) and by attending physicians (543 embryo transfers). RESULTS: There were no differences in the baseline characteristics and IVF cycle parameters between patients who had transfers performed by fellows or attending physicians...
February 9, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29419855/-clinical-report-of-testicular-hypoplasia-combined-with-21-hydroxylase-deficiency
#3
Bo Jiang, Dingyuan Ma, Huanhuan Chen, Xiaoyu Yang, Yugui Cui, Zhengfeng Xu, Jiayin Liu
OBJECTIVE To investigate the correlation of 21-hydroxylase deficiency (21-OHD) with male testicular dysplasia. METHODS Clinical data of 8 infertile males with congenital adrenal hyperplasia due to 21-OHD was retrospectively analyzed. In addition, potential mutations of the CYP21A2 gene was detected. RESULTS All patients were referred because of azoospermia or severe oligospermia and had small testis with averaged testicular volume of 6.1 mL. Three patients had testicular adrenal rest tumors. Endocrinologic examinations revealed low levels of leutinizing hormone and follicular stimulating hormone, normal or elevated testosterone, elevated progesterone, elevated or normal adrenocoticotropic hormone, and low or normal cortisol...
February 10, 2018: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/29366859/endogenous-opiates-and-behavior-2016
#4
REVIEW
Richard J Bodnar
This paper is the thirty-ninth consecutive installment of the annual review of research concerning the endogenous opioid system. It summarizes papers published during 2016 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides, opioid receptors, opioid agonists and opioid antagonists. The particular topics that continue to be covered include the molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors related to behavior, and the roles of these opioid peptides and receptors in pain and analgesia, stress and social status, tolerance and dependence, learning and memory, eating and drinking, drug abuse and alcohol, sexual activity and hormones, pregnancy, development and endocrinology, mental illness and mood, seizures and neurologic disorders, electrical-related activity and neurophysiology, general activity and locomotion, gastrointestinal, renal and hepatic functions, cardiovascular responses, respiration and thermoregulation, and immunological responses...
January 20, 2018: Peptides
https://www.readbyqxmd.com/read/29336014/response-to-yazdani-a-surgery-or-in-vitro-fertilisation-the-simplicity-of-this-question-belies-its-complexity-when-all-you-have-is-a-hammer-everything-looks-like-a-nail
#5
Jason Abbott
This is perhaps the most apt mantra of IVF (in vitro fertilisation) as a treatment in Australasia in this day and age. It is also important to note the truth in the identification of IVF being low skill-based, largely independent of the practitioner, but more importantly costly, and with few exceptions, only available in the private sector. Such revelations really require a rethink of the entire reproductive endocrinology and infertility (CREI) subspecialty. In fact, if there is only one solution to all fertility problems - that of the 'effective IVF procedure' - why not do away completely with the clinician and simply have nurse practitioners who oversee the identified issue of an individual or couple wanting a pregnancy? This in conjunction with the outstanding scientific advances that led to the initiation and promulgation of IVF really would reduce costs by cutting out the unnecessary clinician middle-person who is unimportant in the equation...
February 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29329570/exophthalmos-in-a-young-woman-with-no-graves-disease-a-case-report-of-igg4-related-orbitopathy
#6
Annamaria Erdei, Zita Steiber, Csaba Molnar, Ervin Berenyi, Endre V Nagy
BACKGROUND: Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic Graves' disease. CASE PRESENTATION: A 25-year-old woman has been referred to the endocrinology clinic, 4 months after delivery, with suspected Graves' orbitopathy...
January 12, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29259467/clinical-outcome-of-various-metformin-treatments-for-women-with-polycystic-ovary-syndrome
#7
Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Takeshi Iwasa, Munkhsaikhan Munkhzaya, Kiyohito Yano, Yiliyasi Mayila, Takako Tokui, Rie Yanagihara, Sumika Matsui, Takeshi Kato, Akira Kuwahara, Minoru Irahara
Aim: Polycystic ovary syndrome (PCOS) is an ovulatory disorder and insulin resistance and diabetes are involved in its pathophysiology. Metformin, an anti-diabetic agent, has been reported to be useful to induce ovulation. Methods: Metformin treatment was classified into four types: (1) clomiphene-metformin combination treatment for clomiphene-resistant patients; (2) clomiphene-metformin combination for clomiphene-sensitive patients; (3) clomiphene-metformin combination for naïve patients; and (4) metformin monotherapy...
April 2017: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29258698/monitoring-and-controlling-ovarian-activity-in-wild-felids
#8
Ampika Thongphakdee, Wanlaya Tipkantha, Chainarong Punkong, Kaywalee Chatdarong
In the past decade, studies on reproductive biology, endocrinology, and assisted reproductive technologies (ARTs) in the domestic cat have contributed to a lot of progress in conservation breeding of wild felids. However, the 36 species of the Felidae family have species- and individual-specific reproductive cycles and respond differently to exogenous hormones. Monitoring the ovarian cycle of wild felids can improve their natural breeding and maximize their reproductive success. Moreover, fundamental knowledge on the hormonal patterns of each feline species offers the opportunity to develop ARTs, particularly in threatened and endangered species...
December 11, 2017: Theriogenology
https://www.readbyqxmd.com/read/29247457/progestin-primed-ovarian-stimulation-with-or-without-clomiphene-citrate-supplementation-in-normal-ovulatory-women-undergoing-in-vitro-fertilization-intracytoplasmic-sperm-injection-a-prospective-randomized-controlled-trial
#9
Yali Liu, Qiuju Chen, Sha Yu, Yun Wang, Wen He, Hannah Ya-Ning Chang, Bian Wang, Hongyuan Gao, Hui Long, Li Wang, Qifeng Lyu, Ai Ai, Yanping Kuang
OBJECTIVE: To compare the endocrinological profiles, cycle characteristics and pregnancy outcomes of progestin-primed ovarian stimulation (PPOS) with or without clomiphene citrate (CC) supplementation in normal ovulatory women undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). DESIGN: Prospective randomized controlled study. PATIENT(S): A total of 320 infertile women undergoing IVF/ICSI. Medroxyprogesterone acetate (MPA) and human menopausal gonadotropin (hMG) were simultaneously administered on menstrual cycle day 3...
December 16, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29201073/knowledge-of-thyroid-disorders-during-pregnancy-among-general-practitioners-in-iran
#10
Sahar Askari, Hengameh Abdi, Soleiman Ahmadi, Zahra Bahadoran, Atieh Amouzegar
Background and Objectives: Thyroid disorders during pregnancy are important health problems worldwide. The aim of this study was to assess the knowledge of general practitioners (GPs) about thyroid disorders during pregnancy. Methods: In this cross sectional study, 120 GPs were randomly selected among participants of a continuous medical education (CME) program, entitled "practical endocrinology". To assess the knowledge and educational requirements of GPs regarding thyroid disorders during pregnancy, a validated and localized multiple-choice questionnaire was used...
July 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29171892/parenting-in-the-age-of-preimplantation-gene-editing
#11
Sigal Klipstein
Medical science at its core aims to preserve health and eliminate disease, but a common theme in scientific discovery is the application of findings in ways that were not the primary intent. The development of diagnostic modalities to predict the health of resulting children has been a fundamental aim underpinning research into prenatal and preimplantation diagnostic modalities; however, the knowledge gained has in some cases been utilized for nonmedical purposes. As an example, amniocentesis developed to determine whether the pregnancy is chromosomally normal also provides information about the sex of the fetus, which normally does not affect health...
December 2017: Hastings Center Report
https://www.readbyqxmd.com/read/29148544/reproductive-endocrinology-exposure-to-pesticide-residues-linked-to-adverse-pregnancy-outcomes
#12
Alan Morris
No abstract text is available yet for this article.
November 17, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/29059580/characteristics-of-peripheral-blood-nk-and-nkt-like-cells-in-euthyroid-and-subclinical-hypothyroid-women-with-thyroid-autoimmunity-experiencing-reproductive-failure
#13
Eva Miko, Matyas Meggyes, Katalin Doba, Nelli Farkas, Barbara Bogar, Aliz Barakonyi, Laszlo Szereday, Julia Szekeres-Bartho, Emese Mezosi
Thyroid autoimmunity (TAI) appears to play a crucial role in female infertility, recurrent pregnancy loss and IVF failure. Thyroid autoantibodies against thyroid peroxidase and thyroglobulin have been shown to represent an independent risk factor for infertility and miscarriage. Moreover, thyroxin hormone administration reduces the risk of obstetrical complications in TAI positive women. The aim of our present study was to investigate the immunological background of female infertility and recurrent pregnancy loss in euthyroid and subclinical hypothyroid women with TAI focusing on innate immunity...
September 28, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29055783/prenatal-organochlorine-pesticide-exposure-and-the-disruption-of-steroids-and-reproductive-hormones-in-cord-blood-the-hokkaido-study
#14
Atsuko Araki, Chihiro Miyashita, Takahiko Mitsui, Houman Goudarzi, Futoshi Mizutani, Youichi Chisaki, Sachiko Itoh, Seiko Sasaki, Kazutoshi Cho, Kimihiko Moriya, Nobuo Shinohara, Katsuya Nonomura, Reiko Kishi
Certain organochlorine pesticides (OCPs) are designated as persistent organic pollutants and are regulated in many countries. The effects of OCPs on pediatric endocrinology are a concern; however, only limited data exist from human studies on maternal OCP exposure and its effects on infants' hormone levels. This study was conducted as part of the Hokkaido Study Sapporo Cohort, a prospective birth cohort study in Japan. Participants included 514 women who enrolled at 23-35weeks of gestation between 2002 and 2005; maternal blood samples were collected in late pregnancy, and 29 OCPs were measured...
January 2018: Environment International
https://www.readbyqxmd.com/read/29051074/pairing-ultrasonography-with-endocrinology-to-elucidate-underlying-mechanisms-of-successful-pregnancy-in-the-northern-fur-seal-callorhinus-ursinus
#15
Michelle R Shero, Don R Bergfelt, J Ward Testa, Gregg P Adams
Reproductive success is one of the central tenets of conservation management programs, yet the inability to study underlying physiological processes in a minimally-invasive manner and the unpredictable nature of wild animal populations leaves large gaps in our knowledge of factors critical to successful reproduction in wild species. This study integrated ultrasonography of the reproductive tract and analysis of reproductive hormones in 172 northern fur seals (Callorhinus ursinus) to identify intrinsic factors associated with reinitiating embryonic growth at the end of diapause...
January 1, 2018: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29039178/-potential-clinical-application-of-kisspeptin-in-reproductive-endocrinology
#16
Yanling Fu, Yimin Zhu
Gonadotropin-releasing hormone (GnRH) plays an important role in the process of reproduction. Studies have shown that a family of peptides Kisspeptin can act on GnRH-related neurons, stimulating the secretion of GnRH, and activating the hypothalamic-pituitary-gonadal axis. Both animal experiments and clinical studies have shown that exogenous administration of Kisspeptin is able to induce physiological GnRH release in healthy individuals and those with endocrine-disorders, which brings great hope for treatment of reproductive endocrine diseases...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29018613/relationship-between-hemoglobin-glycation-index-and-extent-of-coronary-heart-disease-in-individuals-with-type-2-diabetes-mellitus-a-cross-sectional-study
#17
Po Chung Cheng, Shang Ren Hsu, Yun Chung Cheng, Yu Hsiu Liu
BACKGROUND: Individuals with type 2 diabetes (T2D) are at an increased risk of coronary heart disease (CHD). Diabetic complications have recently been associated with a measure of glucose metabolism known as the hemoglobin glycation index (HGI). Currently there is insufficient information regarding a potential link between HGI and cardiovascular disease. This study aimed to investigate the relationship between HGI and extent of CHD in individuals with T2D. METHODS: This cross-sectional study screened individuals visiting the endocrinology clinic between June 2012 and May 2016 for eligibility...
2017: PeerJ
https://www.readbyqxmd.com/read/29016514/disparities-in-care-for-publicly-insured-women-with-pregestational-diabetes
#18
Sarah Rae Easter, Emily W Rosenthal, Emma Morton-Eggleston, Nawal Nour, Ruth Tuomala, Chloe A Zera
OBJECTIVE: To investigate the association among public health insurance, preconception care, and pregnancy outcomes in pregnant women with pregestational diabetes. METHODS: This is a retrospective cohort of pregnant women with pregestational type 1 or type 2 diabetes from 2006 to 2011 in Massachusetts-a state with universal insurance coverage since 2006. Women delivering after 24 weeks of gestation and receiving endocrinology and obstetric care in a multidisciplinary clinic were included...
November 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28985546/ovulation-induction-and-controlled-ovarian-stimulation-using-letrozole-gonadotropin-combination-a-single-center-retrospective-cohort-study
#19
Sushila Arya, Sanja Kupesic-Plavsic, Zuber D Mulla, Alok K Dwivedi, Zeni Crisp, Jisha Jose, Luis S Noble
OBJECTIVE: To assess the effect of letrozole in combination with low dose gonadotropins for ovulation induction in anovulatory infertility from polycystic ovary syndrome (PCOS) and controlled ovarian stimulation for endometriosis, and unexplained infertility patients. STUDY DESIGN: Retrospective cohort study in a setting of private Reproductive Endocrinology and Infertility Clinic affiliated with the University. Three hundred couples (650 cycles) requiring OI/COS for PCOS (92 patients, 195 cycles), endometriosis (89 patients, 217 cycles), and unexplained infertility (119 patients, 238 cycles)...
November 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28982961/mechanisms-in-endocrinology-maternal-thyroid-dysfunction-during-pregnancy-and-behavioural-and-psychiatric-disorders-of-children-a-systematic-review
#20
REVIEW
Dagnachew Muluye Fetene, Kim S Betts, Rosa Alati
BACKGROUND: Maternal thyroid dysfunction during pregnancy may lead to persistent neurodevelopmental disorders in the offspring appearing in later life. This study aimed to review the available evidence concerning the relationship between maternal thyroid status during pregnancy and offspring behavioural and psychiatric disorders. METHODS: Systematic electronic database searches were conducted using PubMed, Embase, PsycNET, Scopus, Google Scholar and Cochrane library...
November 2017: European Journal of Endocrinology
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