keyword
MENU ▼
Read by QxMD icon Read
search

Subtype stroke

keyword
https://www.readbyqxmd.com/read/28931222/the-role-of-human-immunodeficiency-virus-associated-vasculopathy-in-the-etiology-of-stroke
#1
Laura A Benjamin, Theresa J Allain, Henry Mzinganjira, Myles D Connor, Colin Smith, Sebastian Lucas, Elizabeth Joekes, Sam Kampondeni, Karen Chetcuti, Ian Turnbull, Mark Hopkins, Steve Kamiza, Elizabeth L Corbett, Robert S Heyderman, Tom Solomon
Background: Human immunodeficiency virus (HIV) infection is a recognized risk factor for stroke among young populations, but the exact mechanisms are poorly understood. We studied the clinical, radiologic, and histologic features of HIV-related ischemic stroke to gain insight into the disease mechanisms. Methods: We conducted a prospective, in-depth analysis of adult ischemic stroke patients presenting to Queen Elizabeth Central Hospital, Blantyre, Malawi, in 2011...
September 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28927686/temporal-trends-in-the-levels-of-peripherally-circulating-leukocyte-subtypes-in-the-hours-after-ischemic-stroke
#2
Dipender Gill, Prasanthi Sivakumaran, Adarsh Aravind, Atisha Tank, Roshni Dosh, Roland Veltkamp
BACKGROUND: Leukocyte-mediated neuroinflammation may affect outcomes after ischemic stroke. AIMS: To explore temporal changes in levels of peripherally circulating leukocyte subtypes in the early hours after ischemic stroke in humans. METHODS: Retrospective analysis of a single-center database of consecutive thrombolysis cases for acute ischemic stroke (AIS). Multivariable regression analysis was used to explore temporal changes in the levels of peripherally circulating leukocyte subtypes in the hours immediately after ischemic stroke...
September 15, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28924103/pravastatin-reduces-the-risk-of-atherothrombotic-stroke-when-administered-within-six-months-of-an-initial-stroke-event
#3
Naohisa Hosomi, Yoji Nagai, Kazuo Kitagawa, Yoko Nakagawa, Shiro Aoki, Tomohisa Nezu, Tatsuo Kagimura, Hirofumi Maruyama, Hideki Origasa, Kazuo Minematsu, Shinichiro Uchiyama, Masayasu Matsumoto
AIMS: The J-STARS study examined whether pravastatin (10 mg/day) reduces recurrence of stroke in non-cardioembolic ischemic stroke patients who were enrolled within 1 month to 3 years after initial stroke events (ClinicalTrials.gov, NCT00221104). The main results showed that the frequency of atherothrombotic stroke was low in pravastatin-treated patients, although no effect of pravastatin was found for the other stroke subtypes. We evaluated differences of early (within 6 months) or late (after 6 months) pravastatin treatment benefits on the incidence of stroke or transient ischemic attack (TIA), as well as atherothrombotic stroke and the other subtypes...
September 16, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28919819/migraine-and-risk-of-stroke-and-acute-coronary-syndrome-in-two-case-control-studies-in-the-danish-population
#4
Merete Osler, Ida Kim Wium-Andersen, Martin Balslev Jørgensen, Terese Sara Høj Jørgensen, Marie Kim Wium-Andersen
INTRODUCTION: Migraine has consistently been associated with increased risk of ischemic stroke, while the evidence for a relation with other types of stroke or coronary outcomes is limited. We examined the association between migraine and stroke and acute coronary syndrome (ACS) subtypes and the influence of potential confounding factors. METHODS: All first-time hospital contacts for stroke (n=155,216) or ACS (n=97,799) were identified in Danish National Patient Registers and matched with 2 control groups of the background population...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28904463/relationship-between-factor-v-leiden-gene-variant-and-risk-of-ischemic-stroke-a-case-control-study
#5
Amit Kumar, Shubham Misra, Ram Sagar, Pradeep Kumar, Arun K Yadav, Pumanshi Talwar, Ritesh Raj, Kameshwar Prasad
BACKGROUND: Factor V Leiden is the most common genetic variation among the blood coagulation pathway which leads to prothrombotic state, therefore, is considered an important gene for understating the stroke mechanism. AIM: The aim of the present study is to determine the relationship between single nucleotide polymorphism at G1691A position of Factor V gene and risk of ischemic stroke (IS) in North Indian population. MATERIALS AND METHODS: In a retrospective case-control study, 250 patients with IS and 250 age- and gender-matched controls were enrolled in the period of October 2012 to September 2014 from in- and out-patient department of Neurology, All India Institute of Medical Sciences, New Delhi, India...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28893252/association-between-carotid-plaque-characteristics-and-acute-cerebral-infarction-determined-by-mri-in-patients-with-type-2-diabetes-mellitus
#6
Beibei Sun, Xiao Li, Xiaosheng Liu, Xiaoqian Ge, Qing Lu, Xihai Zhao, Jun Pu, Jianrong Xu, Huilin Zhao
BACKGROUND: Type 2 diabetes mellitus (T2DM) might aggravate the carotid plaque vulnerability, and increase the risk for ischemic stroke. Few studies reported the acute stroke subtype with carotid plaque characteristics in T2DM patients. This study aimed to investigate the association between carotid plaque characteristics and acute cerebral infarct (ACI) lesion features determined by MRI in T2DM patients. METHODS: Patients with acute cerebrovascular syndrome in internal carotid artery territory were recruited...
September 11, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28890533/dose-response-relationship-between-thrombin-activatable-fibrinolysis-inhibitor-tafi-and-stroke-a-chinese-case-control-study
#7
Huixu Dai, Jingpu Shi, Qiao He, Hao Sun
BACKGROUND Because TAFI (thrombin-activatable fibrinolysis inhibitor) antigen varies widely among different populations, we performed this case-control study to explore the relationship between TAFI levels and stroke in a Chinese population. MATERIAL AND METHODS Our population-based case-control study included 217 stroke patients and 218 healthy controls. The plasma TAFI level was measured by immune turbidimetry. Univariate and multivariate logistic regression analyses were used to analyze the association between different TAFI levels and stroke and its subtypes...
September 11, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28888808/association-of-high-density-lipoprotein-cholesterol-concentration-with-different-types-of-stroke-and-coronary-heart-disease-the-japan-public-health-center-based-prospective-jphc-study
#8
Isao Saito, Kazumasa Yamagishi, Yoshihiro Kokubo, Hiroshi Yatsuya, Hiroyasu Iso, Norie Sawada, Manami Inoue, Shoichiro Tsugane
BACKGROUND AND AIMS: Although low high-density lipoprotein (HDL) cholesterol concentration is an established risk factor for coronary heart disease (CHD), information regarding subtypes of stroke is very limited, especially in Asian populations. METHODS: A prospective study was conducted among 30,736 individuals aged 40-69 years, who lived in nine communities in Japan and did not have a history of cardiovascular disease (CVD). CHD and stroke, including its subtypes, were assessed, and sex-specific hazard ratios (HRs) and 95% confidence intervals (CIs) for outcomes were estimated according to quintiles of HDL cholesterol using Cox proportional models adjusted for other CVD risk factors...
September 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28883775/seasonal-and-monthly-variation-in-stroke-and-its-subtypes-10-year-hospital-based-study
#9
Ahmad Bahonar, Alireza Khosravi, Fariborz Khorvash, Mohammadreza Maracy, Mohammad Saadatnia
BACKGROUND AND OBJECTIVES: There is no evidence of long-term studies of seasonal variations in stroke in Iran. Hence, the aim of this study was to determine the seasonal and monthly variation of 28-day mortality in Isfahan, Iran. METHODS: From 2003 to 2013, In a Hospital-based retrospective study, 24186 cases with first-ever stroke were analyzed in Isfahan. Multinomial logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals (CI) for seasonal and monthly 28-day mortality for stroke in general and three subtypes of stroke including intracranial hemorrhage (ICH), ischemic (IS) and subarachnoid hemorrhage (SAH)...
June 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28882090/stenosis-length-of-middle-cerebral-artery-and-branch-atheromatous-disease-associated-infarct
#10
Jian Wang, Yujie Wang, Zijia Chai, Yue Xin, Jialiang Wang, Jianting Qiu
ABSRACT Background: We analyzed the relationship between the characteristics of branch atheromatous disease associated infarct (BAI) and stenosis length (SL) of relevant middle cerebral artery (MCA) M1 segment. METHODS: 95 patients with BAI were recruited from 1024 consecutive acute ischemic stroke patients. Among them, 59 patients (62.11%) had concurrent relative stenosis of MCA M1 segment. The neurologic deficit severity at admission was assessed by NIHSS and the infarct size by infarct lesion thickness and maximum diameter...
September 8, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28881842/effect-of-age-on-long-term-outcomes-after-stroke-with-atrial-fibrillation-a-hospital-based-follow-up-study-in-china
#11
Tao Wang, Bin Li, Hongfei Gu, Yongzhong Lou, Xianjia Ning, Jinghua Wang, Zhongping An
Atrial fibrillation (AF) is an established predictor of poor outcomes after stroke. We aimed to assess the effect of age on outcomes at 1 year and 3 years in stroke patients with AF. We recruited acute ischemic stroke patients with AF between January 2006 and September 2014 in Tianjin, China. Clinical features and outcomes at 1 year and 3 years after stroke were compared between younger group and elderly group. Overall, 951 consecutive stroke patients with AF were included in this study. There was a higher mortality and dependency rate in the elderly group than in the young group at both 1 and 3 years after stroke...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28881267/gamma-glutamyltransferase-and-cardiovascular-mortality-in-korean-adults-a-cohort-study
#12
Sang-Wook Yi, Sang-Hun Lee, Hee-Jin Hwang, Jee-Jeon Yi
BACKGROUND AND AIMS: Insufficient evidence has been reported on the associations between gamma-glutamyltransferase (GGT) and cardiovascular disease (CVD) mortality from studies with an adequate number of participants. METHODS: 512,990 Korean adults who participated in routine health examinations during the period 2002-2003 were followed up until 2013. Hazard ratios (HRs) were calculated after adjusting for potential confounders. RESULTS: Each 1-unit higher natural-log-transformed GGT (LogeGGT) level was associated with approximately 30-50% higher mortality risk of CVD (HR = 1...
August 26, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28879775/direct-indirect-and-total-bilirubin-and-risk-of-incident-coronary-heart-disease-in-the-dongfeng-tongji-cohort
#13
Xuefeng Lai, Qin Fang, Liangle Yang, Xuguang Chen, Hao Wang, Lin Ma, Wenting Guo, Miao Liu, Handong Yang, Ce Zhang, Xiulou Li, Xinwen Min, Jing Yuan, Mei-An He, Tangchun Wu, Xiaomin Zhang
BACKGROUND: Total bilirubin (TBIL) is known to be inversely associated with coronary heart disease (CHD) risk, however, whether this association is dose-response remains inconsistent and it is unclear which subtype of bilirubin is responsible for the potential protective effect. METHODS: We included 12, 097 participants who were free of CHD, stroke, cancer and potential liver, biliary and renal diseases at baseline from Sep. 2008 to June 2010 and were followed-up until Oct...
September 7, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28873081/impact-of-tag-single-nucleotide-polymorphisms-snps-in-ccl11-gene-on-risk-of-subtypes-of-ischemic-stroke-in-xinjiang-han-populations
#14
Chen Liang, Guihua Ni, Jianhua Ma, Hai Liu, Zhifeng Mao, Honggang Sun, Xiaoning Zhang
BACKGROUND CCL11 is an important inflammatory cytokine associated with inflammation-related diseases such as atherosclerosis and stroke. The aim of this study was to investigate the relationship between CCL11 gene polymorphism with subtypes of ischemic stroke in Xinjiang Han populations. MATERIAL AND METHODS The improved multiple ligase detection reaction (iMLDR) method was used to analyze the genotypes of 6 tag SNPs in the CCL11 gene (rs1129844, rs17809012, rs1860183, rs1860184, rs4795898, and rs4795895) in a case-control study of 406 lacunar stroke patients, 214 large-artery atherosclerotic (LAA) stroke patients, and 425 controls...
September 5, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28870596/common-and-specific-risk-factors-for-ischemic-stroke-in-elderly-differences-based-on-type-of-ischemic-stroke-and-aging
#15
Sayato Fukui, Ryoko Imazeki, Yu Amano, Yousuke Kudo, Kazumitsu Amari, Masahiro Yamamoto, Kikue Todoroki, Yoshimori Ikeya, Takashi Okazaki, Noriharu Yanagimachi, Toru Shizuma, Naoto Fukuyama, Ken Johkura, Hidezo Mori
BACKGROUND: The risk factors among the types of ischemic stroke (atherothrombotic cerebral infarction: ATI, cardio-embolic infarction: CEI, lacunar infarction: LI) in aged stroke patients have rarely been compared to each other. METHODS: We compared the clinical parameters of 300 elderly patients with ischemic stroke, age 65-98years, to 100 age-matched control patients. RESULTS: Comparison by parametric test and logistic regression analysis between all 300 and 100 control patients showed higher systolic and diastolic blood pressures (p<0...
September 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28859026/reexpression-of-prior-stroke-symptoms-in-adults-when-is-a-mimic-a-mimic
#16
James E Siegler, Alexander J George, Sheryl Martin-Schild
A "stroke mimic" refers to any clinical condition that causes neurological symptoms clinically indistinguishable from a cerebral lesion that affects a vascular distribution, but is not caused by ischemia. One subtype of stroke mimic, termed stroke reexpression, is a form of mimicry in which previously recovered or improved stroke symptoms recur in the setting of a neurological disturbance (seizure, hypoperfusion state) or a systemic disturbance (toxic, metabolic, infectious). Many reports of stroke reexpression exist in the literature and are well known to clinicians, but there has been no consensus regarding terminology that has been published to date...
September 2017: Neurologist
https://www.readbyqxmd.com/read/28858643/exploring-putative-inhibitors-of-death-associated-protein-kinase-1-dapk1-via-targeting-gly-glu-leu-gel-and-pro-glu-asn-pen-substrate-recognition-motifs
#17
Pratibha Singh, Priti Talwar
Recently, a new signaling complex Death Associated Protein Kinase 1 (DAPK1) ̶ N-methyl-D-aspartate receptor subtype 2B (NMDAR2B or NR2B) engaged in the neuronal death cascade was identified and it was found that after stroke injury, N-methyl-D-aspartate glutamate (NMDA) receptors interact with DAPK1 through NR2B subunit and lead to excitotoxicity via over-activation of NMDA receptors. An acute brain injury, such as stroke, is a serious life-threatening medical condition which occurs due to poor blood supply to the brain and further leads to neuronal cell death...
August 18, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28856767/risks-of-newly-onset-hemorrhagic-stroke-in-patients-with-neovascular-age-related-macular-degeneration
#18
Wan-Ju Annabelle Lee, Ching-Lan Cheng, Cheng-Han Lee, Yea-Huei Kao Yang, Swu-Jane Lin, Cheng-Yang Hsieh
PURPOSE: Age-related macular degeneration (AMD) is an eye disease causing blindness in the elderly. It shares many common possible pathogenic mechanisms with cardiovascular diseases. Many studies have discussed the association between AMD and stroke, but the results were inconsistent. Our aim was to determine the associations between neovascular AMD and the risk of stroke in the Taiwanese population. METHODS: This is a retrospective cohort study. We used claims data from National Health Insurance Research Database...
August 30, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28854435/n-terminal-prosomatostatin-and-risk-of-vascular-dementia
#19
Hannes Holm, Katarina Nägga, Erik D Nilsson, Fabrizio Ricci, Eduardo Cinosi, Olle Melander, Oskar Hansson, Erasmus Bachus, Martin Magnusson, Artur Fedorowski
BACKGROUND: Increased somatostatin plasma concentration has been found in patients with vascular dementia. However, it is unknown whether or not somatostatin levels may predict dementia development in the general population. To this end, we sought to assess the association of circulating N-terminal prosomatostatin (NT-proSST) with incident dementia among community-dwelling older adults. METHODS: In the prospective population-based Malmö Preventive Project, 5,347 study participants (mean age: 69 ± 6years; 70% men) provided plasma for the determination of NT-proSST concentration...
August 31, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28852707/design-and-rationale-for-examining-neuroimaging-genetics-in-ischemic-stroke-the-mri-genie-study
#20
Anne-Katrin Giese, Markus D Schirmer, Kathleen L Donahue, Lisa Cloonan, Robert Irie, Stefan Winzeck, Mark J R J Bouts, Elissa C McIntosh, Steven J Mocking, Adrian V Dalca, Ramesh Sridharan, Huichun Xu, Petrea Frid, Eva Giralt-Steinhauer, Lukas Holmegaard, Jaume Roquer, Johan Wasselius, John W Cole, Patrick F McArdle, Joseph P Broderick, Jordi Jimenez-Conde, Christina Jern, Brett M Kissela, Dawn O Kleindorfer, Robin Lemmens, Arne Lindgren, James F Meschia, Tatjana Rundek, Ralph L Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Vincent Thijs, Daniel Woo, Bradford B Worrall, Steven J Kittner, Braxton D Mitchell, Jonathan Rosand, Polina Golland, Ona Wu, Natalia S Rost
OBJECTIVE: To describe the design and rationale for the genetic analysis of acute and chronic cerebrovascular neuroimaging phenotypes detected on clinical MRI in patients with acute ischemic stroke (AIS) within the scope of the MRI-GENetics Interface Exploration (MRI-GENIE) study. METHODS: MRI-GENIE capitalizes on the existing infrastructure of the Stroke Genetics Network (SiGN). In total, 12 international SiGN sites contributed MRIs of 3,301 patients with AIS. Detailed clinical phenotyping with the web-based Causative Classification of Stroke (CCS) system and genome-wide genotyping data were available for all participants...
October 2017: Neurology. Genetics
keyword
keyword
106101
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"