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Qi Wang, Wei Li, Danhua Qu, Tong Xin, Peng Gao
RATIONALE: Respiratory syncytial virus (RSV) is a single-stranded negative-sense RNA virus that belongs to the family of paramyxoviruses. RSV is the most common pathogen that causes acute lower respiratory tract infection in infants and young children. However, its incidence in immunocompromised adults remains unclear. In the present study, we report an adult patient with chronic nephropathy, who received long-term immunosuppressants and died of rapid respiratory failure due to RSV infection...
July 2018: Medicine (Baltimore)
Zikai Song, Haidi Wu, Hongyan Cao, Minglong Tang, Shuo Yang, Ling Qin
INTRODUCTION: Pulmonary embolism (PE) is often misdiagnosed, or the diagnosis is delayed because of its diverse clinical manifestations, it may even remain asymptomatic until sudden death. Most risk factors are not associated with young people, and there is a paucity of literature regarding PE in children and young adults. CASE PRESENTATION: Patient 1 who died was diagnosed with nephrotic syndrome more than 10 years before. He presented to a clinic with gradually worsening dyspnea, which was initially misdiagnosed as myocarditis...
July 2018: Medicine (Baltimore)
Xin-Tong Zhang, Wei-Dong Ren
Pompe disease, also called type II glycogen storage disease, is a rare autosomal recessive inherited disease caused by the storage of glycogen in lysosome due to acid α-glucosidase (GAA) deficiency, with the most severe conditions in the skeletal muscle, the myocardium, and the smooth muscle. Patients may have the manifestations of dyspnea and dyskinesia, with or without hypertrophic cardiomyopathy. GAA gene mutation has ethnic and regional differences, and new mutation sites are found with the advances in research...
July 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Marcelo Alcantara Holanda, Renata Dos Santos Vasconcelos, Juliana Carvalho Ferreira, Bruno Valle Pinheiro
Patient-v entilator asynchrony (PVA) is a mismatch between the patient, regarding time, flow, volume, or pressure demands of the patient respiratory system, and the ventilator, which supplies such demands, during mechanical ventilation (MV). It is a common phenomenon, with incidence rates ranging from 10% to 85%. PVA might be due to factors related to the patient, to the ventilator, or both. The most common PVA types are those related to triggering, such as ineffective effort, auto-triggering, and double triggering; those related to premature or delayed cycling; and those related to insufficient or excessive flow...
July 16, 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
İpek Candemir, Pınar Ergün, Dicle Kaymaz, Filiz Taşdemir, Fatma Şengül, Nurcan Egesel
Introduction: Oral nutritional supplement (ONS), an important part of multidisciplinary pulmonary rehabilitation (PR) program, is indicated according to body composition abnormalities in the patients with chronic obtructive pulmonary disease (COPD). We evaluated efficacy of oral nutritional supplement (ONS) during 5-8 months in patients with COPD who completed PR program. Materials and Methods: The data of 41 patients with stable COPD were recorded after the approval had been taken...
March 2018: Tüberküloz Ve Toraks
Alex J Thompson, Joseph A Dearani, Jonathan N Johnson, Hartzell V Schaff, Eric C Towe, Jared Palfreeman, Philip L Wackel, Frank Cetta
BACKGROUND: The transapical approach has been utilized in adult HCM patients with either midventricular obstruction or a small LV cavity; however, there are little data on its use in children. METHODS: We retrospectively reviewed all patients (age <21 years) with HCM who underwent a transapical myectomy from January 2002 to December 2016. Indication for surgery was midventricular obstruction in 19/23 (83%) and small LV cavity in 4 (17%). Preoperative symptoms included: dyspnea (96%), chest pain (65%), presyncope (61%), and syncope (35%)...
July 17, 2018: Congenital Heart Disease
Sowmya Palam, Ridhima Kapoor, Jacquelyn Kulinski
A 62-year-old man presented with 2 weeks of progressive dyspnea and chest pain. He was previously diagnosed with high-grade invasive urothelial carcinoma (UC) of the bladder and underwent neoadjuvant chemotherapy followed by radical cystectomy 10 months earlier, resulting in pathologic complete remission. Clinical evaluation and echocardiographic imaging was consistent with a diagnosis of cardiac tamponade. Due to a history of malignancy, the patient was referred for a surgical pericardial window, to include biopsy of the pericardium...
2018: Case Reports in Cardiology
Daphna Vilozni, Adi Dagan, Moran Lavie, Ifat Sarouk, Bat-El Bar-Aluma, Moshe Ashkenazi, Sarina Levy Mendelovich, Yael Betzalel, Ori Efrati
BACKGROUND: Inspiratory capacity (IC) was scarely considered an important measured index of spirometry in patients with cystic fibrosis (CF). Abnormally low IC may indicate the onset of static/dynamic hyperinflation, which may be accompanied by dyspnea and an increase in the work of breathing. This cross-sectional study sought to determine whether measuring IC during spirometry, may add clinical value to FEV1 measurements in CF subjects. METHODS: Anthropometric, clinical, spirometry, and static lung volume data were gathered retrospectively from 98 of 165 patients with CF (mean ± SD age 26...
July 17, 2018: Respiratory Care
A R Ouedraogo, K Boncoungou, S Maïga, G Ouedraogo, G Badoum, O Diallo, G Bonkoungou, R Nacanabo, M Ouedraogo
INTRODUCTION: Abnomalies of the aortic arches are rare and account for 1% of congenital cardiovascular malformations. They constitute one of the causes of compression of the airways with attacks of dyspnea sometimes simulating an asthma. We report the case of an infant with an anomaly development of aortic arches with impact breathing. CASE REPORT: It was a 22-month-old infant who consulted for a dyspnea with a type of stridor associated with a fat cough. This clinical table started 45 days after its birth and led to many hospitalizations in the pediatric emergency...
July 14, 2018: Revue de Pneumologie Clinique
Wai Keat Wong, Subhaschandra Shetty, Randall P Morton, Nicholas P McIvor, Tony Zheng
OBJECTIVE: Data pertaining to the outcomes of retrosternal goiter surgeries performed at secondary care centers, where thoracic surgery expertise is not readily available, is infrequently reported. Careful patient selection is crucial to avoid an unexpected need for a sternotomy during surgery. We sought to evaluate the surgical management of patients with retrosternal goiters treated at two secondary care centers. METHODS: Retrospective review of clinical records and computed tomographic (CT) scans of 557 patients who underwent thyroid surgery at the Departments of Otolaryngology, Head and Neck Surgery of Manukau Surgery Center and Whangarei Base Hospital...
July 12, 2018: Auris, Nasus, Larynx
Anne Kirstine Høyer-Nielsen, Shahin Gaini, Anne Kjerulf, Rudi Kollslíð, Torkil Á Steig, Marc Stegger, Jan Jóanesarson
Streptococcus equi subspecies zooepidemicus ( S. zooepidemicus ) is mostly known as an opportunistic pathogen found in horses and as a rare human zoonosis. An 82-year-old male, who had daily contact with horses, was admitted in a septic condition. The patient presented with dyspnea, hemoptysis, impaired general condition, and severe pain in a swollen left shoulder. Synovial fluid from the affected joint and blood cultures showed growth of S. equi subsp. zooepidemicus . Transesophageal echocardiography showed a vegetation on the aortic valve consistent with endocarditis...
2018: Case Reports in Infectious Diseases
Sucui Zhu, Kun Shi, Jin Yan, Zhiping He, Yan Wang, Qifeng Yi, Hui Huang
BACKGROUND AND OBJECTIVE: 24-form Tai Chi is a traditional exercise popular among old people in China, but it has some complex movements beyond of capabilities of patients with COPD. This study was to modify and simplify 24-form Tai Chi and evaluate effects of the modified Tai Chi on lung function, exercise capacity, dyspnea symptom and health status in patients with COPD. METHODS: A two-step procedure was applied: an initial qualitative research module consisting of focus group discussion, expert consultation and patient interviews was conducted to simplified and modified 24-form Tai Chi for patients with COPD...
August 2018: Complementary Therapies in Medicine
Cristian Aguilar, Daniel Espinoza, Renzo Soca
Intravascular leiomyomatosis is a rare condition characterized by histologically benign smooth muscle cell growth within the uterine veins and inferior vena cava and, rarely, into the right chambers of the heart. A 39-year-old female with a history of hysterectomy for uterine leiomyoma was admitted for lower limb oedema and progressive dyspnea of 5 months' duration. Transthoracic echocardiography and contrast-enhanced computed tomography showed a large mass extending through the inferior vena cava into the right chambers of the heart...
July 2018: Revista Española de Patología
Caroline Bodi Winn, Stephen C Artim, Morgan S Jamiel, Monika A Burns, Jennifer L Haupt, James G Fox, Sureshkumar Muthupalani
A 6-y-old, intact, pair-housed male common marmoset (Callithrix jacchus) presented with acute onset dyspnea and tachypnea immediately after sedation with alfaxalone; a history of gradual weight loss initiated the examination under sedation. Thoracic radiographs revealed significant right-lung consolidation, with a vesicular gas pattern in the right caudodorsal lung field, pleural effusion, and dorsal displacement of the heart. The marmoset was euthanized due to his unstable condition and poor prognosis. At necropsy, the cranial and middle lobes of the right lung were homogenously dark red-brown, enlarged, edematous, and twisted around the longitudinal axis at the hilus...
July 16, 2018: Comparative Medicine
Chien-Yi Hsu, Yu-Wen Su, San-Chi Chen
BACKGROUND: Use of anti-programmed cell death-1 (anti-PD-1) has been successful in treating many types of cancers. Despite its promising efficacy, immune-related adverse events are still a major concern. Immune-related cardiotoxicity, which is rare but fatal, has recently become a focus of attention. Cardiotoxicities including myocarditis, cardiomyopathy, cardiac fibrosis, heart block and cardiac arrest have been reported. Of these toxicities, myocarditis is often accompanied by dysrhythmia...
July 16, 2018: Journal for Immunotherapy of Cancer
Francesc Medina-Mirapeix, Roberto Bernabeu-Mora, Luz María Giménez-Giménez, Pilar Escolar-Reina, Mariano Gacto-Sánchez, Silvana Loana de Oliveira-Sousa
BACKGROUND: The physical frailty status affects the health status of patients with chronic obstructive pulmonary disease (COPD). The objective was to determine if the individual physical frailty characteristics have a differential impact on the CAT score. METHODS: This observational study included 137 patients with stable COPD. Physical frailty was measured with unintentional weight loss, low physical activity, exhaustion, slow walking speed and low grip strength and health status assessed with the COPD Assessment test (CAT)...
July 16, 2018: Health and Quality of Life Outcomes
Cássio Magalhães da Silva E Silva, Mansueto Gomes Neto, Micheli Bernardone Saquetto, Cristiano Sena da Conceição, Adelmir Souza-Machado
OBJECTIVE: To evaluate the effects of upper limb resistance exercise on the functional capacity, muscle function, and quality of life in patients with chronic obstructive pulmonary disease. SETTING: Clinical School of Physiotherapy in a Public University of Brazil. SUBJECTS: 58 patients were recruited; of these, 7 were excluded and 51 individuals were enrolled. INTERVENTION: Control group performed warm-up, aerobic exercise, inspiratory muscle training, and session stretching, followed by massage therapy...
July 1, 2018: Clinical Rehabilitation
Jun Kako, Tatsuya Morita, Takuhiro Yamaguchi, Masamitsu Kobayashi, Asuko Sekimoto, Hiroya Kinoshita, Asao Ogawa, Sadamoto Zenda, Yosuke Uchitomi, Hironobu Inoguchi, Eisuke Matsushima
CONTEXT: Dyspnea is a common distressing symptom among patients with advanced cancer. OBJECTIVE: To determine the effect of fan therapy on dyspnea in terminally ill cancer patients. METHODS: This parallel arm, randomized controlled trial included 40 patients with advanced cancer from a palliative care unit at the National Cancer Center Hospital in Japan. All patients experienced dyspnea at rest with a score of at least 3 points on a subjective 0-10-point numerical rating scale (NRS), showed peripheral oxygen saturation levels of ≥90%, an Eastern Cooperative Oncology Group grade of 3 or 4, and were aged 20 years or more...
July 12, 2018: Journal of Pain and Symptom Management
Mahdi Pishgahi, Toktam Alirezaei, Behzad Hajimoradi, S Mojtaba Nekooghadam, Shima Shahi
In massive pulmonary embolism (PE), fibrinolytic therapy is a potential lifesaving treatment; therefore, if other treatments are not available, the physicians encounter this question: can we accept the risk of complications from fibrinolytic therapy, especially intracranial hemorrhage, in the presence of absolute contraindication, in order to save the patient's life? Here, we describe three cases of massive PE with absolute contraindication for fibrinolytic therapy who presented to emergency department following dyspnea...
2018: Emergency (Tehran, Iran)
Argyrios Ioannidis, Christos Koutserimpas, Michael Konstantinidis, Ioannis Drikos, Panagiotis Voulgaris, Nikolaos Economou
Liposarcomas are the most common soft tissue tumors with various histological subtypes. They usually appear in the retroperitoneal region of the abdomen, but their symptomatology remains unclear and their diagnosis, as well as treatment challenging. A case of a 55-year-old female patient with dyspnea and light diffuse abdominal pain caused by a giant retroperitoneal liposarcoma is presented. The patient had an unremarkable medical history, while the computed tomography scan revealed a large mass at the right portion of the abdomen, with its upper limits to the lower edge and the gate portion of the liver...
August 2018: Oncology Letters
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