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https://www.readbyqxmd.com/read/28880869/differences-in-chemical-constituents-of-artemisia-annua-l-from-different-geographical-regions-in-china
#1
Xiaobo Zhang, Yuping Zhao, Lanping Guo, Zhidong Qiu, Luqi Huang, Xiaobo Qu
BACKGROUND: Daodi-herb is a part of Chinese culture, which has been naturally selected by traditional Chinese medicine clinical practice for many years. Sweet wormwood herb is a kind of Daodi-herb, and comes from Artemisia annua L. Artemisinin is a kind of effective antimalarial drug being extracted from A. annua. Because of artemisinin, Sweet wormwood herb earns a reputation. Based on the Pharmacopoeia of the People's Republic of China (PPRC), Sweet wormwood herb can be used to resolve summerheat-heat, and prevent malaria...
2017: PloS One
https://www.readbyqxmd.com/read/28829416/quantitative-localization-of-a-golgi-protein-by-imaging-its-center-of-fluorescence-mass
#2
Hieng Chiong Tie, Bing Chen, Xiuping Sun, Li Cheng, Lei Lu
The Golgi complex consists of serially stacked membrane cisternae which can be further categorized into sub-Golgi regions, including the cis-Golgi, medial-Golgi, trans-Golgi and trans-Golgi network. Cellular functions of the Golgi are determined by the characteristic distribution of its resident proteins. The spatial resolution of conventional light microscopy is too low to resolve sub-Golgi structure or cisternae. Thus, the immuno-gold electron microscopy is a method of choice to localize a protein at the sub-Golgi level...
August 10, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28820411/-importance-of-shear-wave-elastography-of-livers-in-practically-healthy-pregnant-women
#3
E Sariyeva, S Salahova, N Bayramov
Pulse-wave elastography (SWE) that is one of the mostly used methods in the recent years holds important place in assessment of liver fibrosis. However there is no exact information on the results of liver elastography in healthy pregnant women in the world literature. The aim of the study was to investigate theSWE parameters of liver elastography in practically healthy pregnant women. The subject of the research was 50 practically healthy pregnant women within 18-45 years old (mean age 27.7±0.7). The pregnant women with genital and extragenital diseases were not included to the research...
July 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28803679/systematic-review-of-the-methods-predictive-of-the-functionality-of-kidney-transplantation
#4
E Miret Alomar, E Trilla Herrera, D Lorente Garcia, L Regis Placido, R López Del Campo, M Cuadras Solé, T Pont Castellana, F Moreso Mateos, D Serón Micas, J Morote Robles
CONTEXT: Kidney transplantation from donors with expanded criteria has increased the pool of kidneys at the cost of a higher risk of short and long-term graft dysfunction. The main issue lies in determining which kidneys will offer acceptable function and survival compared with the risk represented by surgery and subsequent immunosuppression. OBJECTIVE: The objective of our article is to review the current evidence on the tools for predicting the functionality of kidney transplantation from cadaveric donors with expanded criteria and determining the validity for their use in standard practice...
August 10, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28790311/plasmonic-silver-nanoshells-for-drug-and-metabolite-detection
#5
Lin Huang, Jingjing Wan, Xiang Wei, Yu Liu, Jingyi Huang, Xuming Sun, Ru Zhang, Deepanjali D Gurav, Vadanasundari Vedarethinam, Yan Li, Ruoping Chen, Kun Qian
In-vitro metabolite and drug detection rely on designed materials-based analytical platforms, which are universally used in biomedical research and clinical practice. However, metabolic analysis in bio-samples needs tedious sample preparation, due to the sample complexity and low molecular abundance. A further challenge is to construct diagnostic tools. Herein, we developed a platform using silver nanoshells. We synthesized SiO2@Ag with tunable shell structures by multi-cycled silver mirror reactions. Optimized nanoshells achieved direct laser desorption/ionization mass spectrometry in 0...
August 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28782348/factors-affecting-oral-health-determinants-in-female-university-students-a-cross-sectional-survey-in-saudi-arabia
#6
Najla S Dar-Odeh, Fatimah Ali Aleithan, Ahmad A Alnazzawi, Mohammad H Al-Shayyab, Shaden O Abu-Hammad, Osama A Abu-Hammad
Objective This study aims at investigating factors affecting oral health patterns, attitudes and health risk behaviors among female university students. Methods An online questionnaire was distributed to female university students in Al Madinah in the western region of Saudi Arabia. Students were requested to answer questions on demographic data, oral hygiene practices, dental attendance, smoking history, practice of sports and body weight and height. Results Two hundred and fourteen students participated with age range of 18-31 years (mean = 21...
August 1, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28751633/chemical-characterization-of-the-adhesive-secretions-of-the-salamander-plethodon-shermani-caudata-plethodontidae
#7
Janek von Byern, Ingo Grunwald, Max Kosok, Ralph A Saporito, Ursula Dicke, Oliver Wetjen, Karsten Thiel, Kai Borcherding, Thomas Kowalik, Martina Marchetti-Deschmann
Salamanders have developed a wide variety of antipredator mechanisms, including tail autotomy, colour patterns, and noxious skin secretions. As an addition to these tactics, the red-legged salamander (Plethodon shermani) uses adhesive secretions as part of its defensive strategy. The high bonding strength, the fast-curing nature, and the composition of the biobased materials makes salamander adhesives interesting for practical applications in the medical sector. To understand the adhesive secretions of P. shermani, its components were chemically analysed by energy dispersive X-ray spectroscopy (EDX), inductively coupled plasma mass spectrometry (ICP-MS), amino acid analysis, and spectroscopy (ATR-IR, Raman)...
July 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747802/rashba-spin-orbit-coupling-in-graphene-monolayer-coated-by-periodic-magnetic-stripes
#8
Xiaojing Li, Zhenhua Wu, Jiangtao Liu
We investigate theoretically the effects of a modulated periodic perpendicular magnetic fields and the Rashba spin-orbit coupling (RSOC) on the electronic states and optical absorption spectrum in a graphene monolayer. The magnetic fields and supperlattice geometry give rise to distinct Dirac cone shift and open a finite bandgap at the Dirac point. In contrast to the energy spectrum without the RSOC interaction, we find that the RSOC term will develop a spin-splitting energy-momentum dispersion relation in this graphene magnetic supperlattice...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28745635/a-practical-guide-on-coupling-a-scanning-mobility-sizer-and-inductively-coupled-plasma-mass-spectrometer-smps-icpms
#9
Mohamed Tarik, Debora Foppiano, Adrian Hess, Christian Ludwig
A large variety of analytical methods are available to characterize particles in aerosols and suspensions. The choice of the appropriate technique depends on the properties to be determined. In many fields information about particle size and chemical composition are of great importance. While in aerosol techniques particle size distributions of gas-borne particles are determined online, their elemental composition is commonly analyzed offline after an appropriate sampling and preparation procedure. To obtain both types of information online and simultaneously, a hyphenated setup was recently developed, including a Scanning Mobility Particle Sizer (SMPS) and an Inductively Coupled Plasma Mass Spectrometer (ICPMS)...
July 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28744821/evaluating-the-effect-of-instruction-and-practice-schedule-on-the-acquisition-of-ecg-interpretation-skills
#10
Sandra Monteiro, Lindsay Melvin, Joshua Manolakos, Ameen Patel, Geoffrey Norman
INTRODUCTION: Evidence of the benefit of distributed instruction and interleaved practice comes from studies using simple materials (e. g. word pairs). Furthermore, there is currently no evidence of the combined impact of these strategies in undergraduate medical education. The present study evaluated the impact of varying both instruction and practice schedules for the acquisition of ECG interpretation skills. METHODS: We conducted a 2 × 2 factorial study with two levels of instruction (massed and distributed) and two levels of practice (interleaved and blocked)...
August 2017: Perspectives on Medical Education
https://www.readbyqxmd.com/read/28742613/the-influence-of-heavier-football-helmet-faceguards-on-head-impact-location-and-severity
#11
Julianne D Schmidt, Tracy T Phan, Ron W Courson, Fred Reifsteck, Eric D Merritt, Cathleen N Brown
OBJECTIVE: To determine whether players with heavier faceguards have increased odds of sustaining top of the head impacts and head impacts of higher severity. DESIGN: Cohort study. SETTING: On-field. PARTICIPANTS: Thirty-five division I collegiate football players. INTERVENTIONS: Faceguard mass was measured. Head impact location and severity (linear acceleration [gravity], rotational acceleration [radian per square second], and Head Impact Technology severity profile [unitless]) were captured for 19 379 total head impacts at practices using the Head Impact Telemetry System...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28742051/cooperative-tracking-of-networked-agents-with-a-high-dimensional-leader-qualitative-analysis-and-performance-evaluation
#12
Guanghui Wen, Tingwen Huang, Wenwu Yu, Yuanqing Xia, Zhi-Wei Liu
Cooperative consensus tracking and its L²-gain performance is investigated in this paper for a class of multiple agent systems (MASs) in the presence of a single high-dimensional leader. Compared with the traditional models for MASs, the inherent dynamics of the leader are allowed to be different with those of the followers in the present framework, which is thus much more favorable in various practical applications. A new kind of distributed controllers associated with a reduced-order state observer are designed for each follower to track the high-dimensional leader under directed switching topology...
July 21, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28718178/body-composition-is-different-after-surgical-or-pharmacological-remission-of-cushing-s-syndrome-a-prospective-dxa-study
#13
Filippo Ceccato, Michela Boccato, Marialuisa Zilio, Mattia Barbot, Anna Chiara Frigo, Giovanni Luisetto, Marco Boscaro, Carla Scaroni, Valentina Camozzi
Patients with active Cushing's syndrome (CS) exhibit an increase of the visceral adipose tissue, increasing the risk of cardiovascular events. Until now, it is not yet clear whether remission of CS leads to a normalization of body composition, or if different strategies to control hypercortisolism could result in a different clinical outcome concerning adipose tissue distribution. Therefore, we analyzed body composition changes using dual-energy X-ray absorptiometry (DXA) in patients with CS in a prospective and controlled study...
September 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28717813/cut-off-points-for-muscle-mass-not-grip-strength-or-gait-speed-determine-variations-in-sarcopenia-prevalence
#14
F Masanés, X Rojano I Luque, A Salvà, J A Serra-Rexach, I Artaza, F Formiga, F Cuesta, A López Soto, D Ruiz, A J Cruz-Jentoft
OBJECTIVES: The European Working Group on Sarcopenia in Older People (EWGSOP) has proposed different methods and cut-off points for the three parameters that define sarcopenia: muscle mass, muscle strength and physical performance. Although this facilitates clinical practice, it limits comparability between studies and leads to wide differences in published prevalence rates. The aim of this study was to assess how changes in cut-off points for muscle mass, gait speed and grip strength affected sarcopenia prevalence according to EWGSOP criteria...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28711005/pesticide-occurrence-in-the-waters-of-j%C3%A3%C2%BAcar-river-spain-from-different-farming-landscapes
#15
Juan Antonio Pascual Aguilar, Vicente Andreu, Julián Campo, Yolanda Picó, Ana Masiá
A combined methodology to identify and quantify farming chemicals in the entire Júcar River basin has been developed. The procedure consisted of the application of environmental forensic criteria associating laboratory analytical samples, cartographic analysis using Geographical Information Systems (GIS) and synthetic statistical analysis. Sampling involved the collection of 15 samples in surface waters distributed alongside the Júcar River and its two main tributaries (Cabriel and Magro Rivers). The analytical procedure involves generic sample extraction and selective determination of up to 50 target pesticides by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28701204/criteria-and-models-for-the-distribution-of-casualties-in-trauma-related-mass-casualty-incidents-a-systematic-literature-review-protocol
#16
Ali Ardalan, Mohammad Reza Khajehaminian, Sayed Mohsen Hosseini Boroujeni, Amir Nejati, Abbasali Keshtkar, Abbas Rahimi Foroushani, Omid Mahdi Ebadati E
BACKGROUND: One of the most critical practices in mass casualty incident management is vacating the victims from scene of the incident and transporting them to proper healthcare facilities. Decision on distribution of casualties needs to be taken on pre-developed policies and structured decision support mechanisms. While many studies tried to present models for the distribution of casualties, no systematic review has yet been conducted to evaluate the existing models on casualty distribution following mass casualty incidents...
July 12, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28699651/combination-of-thresholding-and-fitting-methods-for-measuring-nanoparticle-sizes-and-size-distributions-in-s-tem
#17
Dmitry O Shvedchenko, Elena I Suvorova
The practical need for a simple and reliable tool for routine size analysis of nanoparticles with diameters down to a few nm embedded in a polymer matrix motivated the development of a new approach. The idea underlying the method proposed in this work is to combine intensity thresholding and contrast fitting procedures in the same software for particle recognition and measurements of sizes and size distributions of nanoparticles in transmission and scanning transmission electron microscopy images. Particle recognition in images is performed in an interactive process of manual setting the numerical threshold level after image preprocessing...
July 12, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28699306/strategies-for-building-a-successful-ultrasound-guided-fna-practice-in-department-of-pathology-experience-at-a-university-hospital
#18
Maoxin Wu, Kenneth R Shroyer
INTRODUCTION: Although pathology services focused on fine needle aspiration (FNA) biopsy of superficial palpable masses with on-site cytological evaluation are available in a wide range of clinical and academic settings, the addition of ultrasound (US) guidance into FNA practice by a cytopathologist group can be challenging. An US-FNA service provided by a cytopathologist in the department of Pathology is a relatively new practice in the field of medicine. This report summarizes our experience and strategies in achieving this objective and our successful preliminary results...
July 11, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28695328/study-of-the-emitted-dose-after-two-separate-inhalations-at-different-inhalation-flow-rates-and-volumes-and-an-assessment-of-aerodynamic-characteristics-of-indacaterol-onbrez-breezhaler-%C3%A2-150-and-300%C3%A2-%C3%AE-g
#19
Mohamad Abadelah, Henry Chrystyn, Golshan Bagherisadeghi, Gaballa Abdalla, Hassan Larhrib
Onbrez Breezhaler® is a low-resistance capsule-based device that was developed to deliver indacaterol maleate. The study was designed to investigate the effects of both maximum flow rate (MIF) and inhalation volume (Vin) on the dose emission of indacaterol 150 and 300 μg dose strengths after one and two inhalations using dose unit sampling apparatus (DUSA) as well as to study the aerodynamic characteristics of indacaterol Breezhaler® using the Andersen cascade impactor (ACI) at a different set of MIF and Vin...
July 10, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28688270/simultaneous-quantitative-analysis-of-polyethylene-glycol-peg-pegylated-paclitaxel-and-paclitaxel-in-rats-by-ms-ms-all-technique-with-hybrid-quadrupole-time-of-flight-mass-spectrometry
#20
Heping Sun, Qi Zhang, Zhi Zhang, Jin Tong, Dafeng Chu, Jingkai Gu
PEGylation is practically one of most important modifications of drugs including small molecules, peptides and proteins, which has been proven to dramatically improve physicochemical properties and pharmacokinetic behavior of the PEGylated drugs. However, it is a challenge currently to quantitatively analyze PEG and PEGylated drugs by various analytical methods, even mass spectrometry because of multiple parent ion distribution of PEG caused by its polydispersity of molecular weight. Here we developed a robust method with MS/MS(ALL) technique using electrospray ionization (ESI) source coupled high resolution Quadrupole Time-of-Flight (Q-TOF) mass spectrometry for the quantification of PEG2K-Paclitaxel (PEG-PTX) and its two metabolites, PEG and Paclitaxel (PTX)...
October 25, 2017: Journal of Pharmaceutical and Biomedical Analysis
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