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Rejuvenation Research

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https://www.readbyqxmd.com/read/28185732/water-resources-management-in-the-urban-agglomeration-of-the-lake-biwa-region-japan-an-ecosystem-services-based-sustainability-assessment
#1
Xiaochen Chen, Yuqing Chen, Toshiyuki Shimizu, Jia Niu, Ken'ichi Nakagami, Xuepeng Qian, Baoju Jia, Jun Nakajima, Ji Han, Jianhua Li
An innovative ecosystem services-based sustainability assessment was conducted in the important urban agglomeration of the Lake Biwa region, Japan, covering the time period from 1950 to 2014. A 22-indicator system was established that was based on the major ecosystem services of Lake Biwa and its water courses, i.e., provisioning services regarding aquatic products and water; regulating services regarding floods and water quality; cultural services regarding recreation and tourism, scientific research, and environmental education; and supporting services regarding biodiversity...
February 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28154735/preventing-aging-with-stem-cell-rejuvenation-feasible-or-infeasible
#2
EDITORIAL
Kanya Honoki
Characterized by dysfunction of tissues, organs, organ systems and the whole organism, aging results from the reduced function of effective stem cell populations. Recent advances in aging research have demonstrated that old tissue stem cells can be rejuvenated for the purpose of maintaining the old-organ function by youthful re-calibration of the environment where stem cells reside. Biochemical cues regulating tissue stem cell function include molecular signaling pathways that interact between stem cells themselves and their niches...
January 26, 2017: World Journal of Stem Cells
https://www.readbyqxmd.com/read/28152565/sphere-induced-rejuvenation-of-swine-and-human-m%C3%A3-ller-glia-is-primarily-caused-by-telomere-elongation
#3
Ni Xu, Yao Chen, Kevin C Dean, Xiaoqin Lu, Xiao Liu, Wei Wang, Douglas C Dean, Henry J Kaplan, Ling Gao, Fangtian Dong, Yongqing Liu
Müller cells are the major supportive and protective glial cells in the retina with important functions in histogenesis and synaptogenesis during development, and in maintenance of mature neurons as they show to secrete various cytokines and manifest potentials of self-renewal and transdifferentiation into retinal neurons following injury in the vertebrate retinas. The swine retina has a visual streak structure similar to the human macular where cone photoreceptors are highly concentrated, thereby can serve as a better model for studying retinal diseases and for formulating cell-based therapeutics than the rodent retinas...
February 2, 2017: Stem Cells
https://www.readbyqxmd.com/read/28088983/the-epigenetic-basis-of-hematopoietic-stem-cell-aging
#4
REVIEW
Ashley Kramer, Grant A Challen
Highly proliferative tissues such as the gut, skin, and bone marrow lose millions of cells each day to normal attrition and challenge from different biological adversities. To achieve a lifespan beyond the longevity of individual cell types, tissue-specific stem cells sustain these tissues throughout the life of a human. For example, the lifespan of erythrocytes is about 100 days and adults make about two million new erythrocytes every second. A small pool of hematopoietic stem cells (HSCs) in the bone marrow is responsible for the lifetime maintenance of these populations...
January 2017: Seminars in Hematology
https://www.readbyqxmd.com/read/28001455/assessment-of-efficacy-and-safety-of-a-fractionated-bipolar-radiofrequency-device-for-the-treatment-of-lower-face-wrinkles-and-laxity
#5
Yueqi Jiang, Xuting Zhang, Zhong Lu, Michael H Gold
Skin aging, as a natural course, is a gradual process. It can be classified as either intrinsic or photo-aging. In recent years, as the attention to lower face wrinkles and laxity has raised significantly, the demands to facial rejuvenation also increased, along with a variety of technologies coming into being. Fractional bipolar RF as a novel means of rejuvenation has been used in clinical practice, but questions remain in terms of its efficacy and safety. Considering a large population in our country and huge demands for skin tightening, we did this research to evaluate the efficacy and safety of fractional bipolar radiofrequency...
December 21, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27987257/a-new-tool-to-improve-delivery-of-patient-engaged-care-and-satisfaction-in-facial-treatments-the-aesthetic-global-ranking-scale
#6
Ravi Jain, Peter Huang, Rodrigo M Ferraz
BACKGROUND: Physicians face the challenge of individualizing aesthetic treatments in order to match the aesthetic needs of patients with their expectations. OBJECTIVE: To review issues underlying patient satisfaction with minimally invasive aesthetic treatment and to present a patient-centric assessment tool (the Global Ranking Scale [GRS]) designed to set higher standards for patient consultation and treatment experience; ensure a comprehensive patient-centric aesthetic consultation process; and raise patient satisfaction with facial rejuvenation treatment...
December 16, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27922559/botulinum-toxin-type-a-bont-a-injections-of-the-corrugator-muscles-for-aesthetics-and-depression
#7
Connie Brennan
The treatment of glabellar lines with botulinum toxin type-A (BoNT-A) is a staple for aesthetic providers who specialize in facial rejuvenation. Clinical efforts are currently underway to substantiate upper facial injections (the corrugator muscles are the target muscles) of BoNT-A as an antidepression therapy. This article describes the origin of "facial feedback" by Charles Darwin nearly 150 years ago, as well as "emotional proprioception"-2 neuroanatomical concepts that help provide the scientific rationale behind the general influence facial muscles have on the emotional centers of the brain, and, specifically, how the corrugator muscles-involved with frowning-promote a gloomy mood...
October 2016: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/27854193/a-comprehensive-review-on-edible-bird-nests-and-swiftlet-farming
#8
REVIEW
Lee Suan Chua, Siti Najihah Zukefli
Edible bird's nest (EBN) is currently widely consumed by the Chinese community as tonic food and functional food, which is believed to have many medicinal benefits. Some studies have reported the biochemical compositions of EBN, graded on the basis of colour, nitrate and nitrite contents. Other studies have shown significant biological effects, while ongoing research is in progress to explore potential pharmacological applications. The high demand for EBNs in the global market has forced the local regulatory bodies to monitor swiftlet farming activities, including the EBN cleaning process...
November 2016: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27842480/mesenchymal-stem-cells-as-a-source-of-dopaminergic-neurons-a-potential-cell-based-therapy-for-parkinson-s-disease
#9
Katari Venkatesh, Dwaipayan Sen
Cell repair/replacing strategies for neurodegenerative diseases such as Parkinson's disease depend on well-characterized dopaminergic neuronal candidates that are healthy and show promising effect in the rejuvenation of degenerated area of the brain. Therefore, it is imperative to develop innovative therapeutic strategies that replace damaged neurons with new/functional dopaminergic neurons. Although several research groups have reported the generation of neural precursors/neurons from human/mouse embryonic stem cells and mesenchymal stem cells, the latter is considered to be an attractive therapeutic candidate because of its high capacity for self-renewable, no adverse effect to allogeneic versus autologous transplants, high ethical acceptance and no teratoma formation...
November 14, 2016: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27830812/ageing-neurodegeneration-and-brain-rejuvenation
#10
REVIEW
Tony Wyss-Coray
Although systemic diseases take the biggest toll on human health and well-being, increasingly, a failing brain is the arbiter of a death preceded by a gradual loss of the essence of being. Ageing, which is fundamental to neurodegeneration and dementia, affects every organ in the body and seems to be encoded partly in a blood-based signature. Indeed, factors in the circulation have been shown to modulate ageing and to rejuvenate numerous organs, including the brain. The discovery of such factors, the identification of their origins and a deeper understanding of their functions is ushering in a new era in ageing and dementia research...
10, 2016: Nature
https://www.readbyqxmd.com/read/27818905/new-insights-into-intrinsic-point-defects-in-v2vi3-thermoelectric-materials
#11
Tiejun Zhu, Lipeng Hu, Xinbing Zhao, Jian He
Defects and defect engineering are at the core of many regimes of material research, including the field of thermoelectric study. The 60-year history of V2VI3 thermoelectric materials is a prime example of how a class of semiconductor material, considered mature several times, can be rejuvenated by better understanding and manipulation of defects. This review aims to provide a systematic account of the underexplored intrinsic point defects in V2VI3 compounds, with regard to (i) their formation and control, and (ii) their interplay with other types of defects towards higher thermoelectric performance...
July 2016: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/27810629/the-integration-and-evaluation-of-a-social-media-facilitated-journal-club-to-enhance-the-student-learning-experience-of-evidence-based-practice-a-case-study
#12
Caleb Ferguson, Michelle DiGiacomo, Leila Gholizadeh, Leila E Ferguson, Louise D Hickman
INTRODUCTION: Nurses are required to interpret and apply knowledge so communities will receive care based on best available evidence, as opposed to care that is simply based on tradition or authority. Fostering nursing students' critical appraisal skills will assist in their capacity to engage with, interpret and use best evidence. Journal clubs are frequently used approach to engage learners with research and develop critical appraisal skills. Given new flipped and blended approaches to teaching and learning there is need to rejuvenate how research is utilised and integrated within journal clubs to maximise engagement and translation of evidence...
January 2017: Nurse Education Today
https://www.readbyqxmd.com/read/27752651/nanoscale-chirality-in-metal-and-semiconductor-nanoparticles
#13
Jatish Kumar, K George Thomas, Luis M Liz-Marzán
The field of chirality has recently seen a rejuvenation due to the observation of chirality in inorganic nanomaterials. The advancements in understanding the origin of nanoscale chirality and the potential applications of chiroptical nanomaterials in the areas of optics, catalysis and biosensing, among others, have opened up new avenues toward new concepts and design of novel materials. In this article, we review the concept of nanoscale chirality in metal nanoclusters and semiconductor quantum dots, then focus on recent experimental and theoretical advances in chiral metal nanoparticles and plasmonic chirality...
October 18, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27697004/intense-pulsed-light-from-the-past-to-the-future
#14
Dan Li, Shi-Bin Lin, Biao Cheng
BACKGROUND: For 20 years, intense pulsed light (IPL) technology has been used to treat various medical problems. IPL has since developed rapidly, becoming popular among patients worldwide. Recently, IPL has been used mainly for cosmetic purposes. Researchers are constantly seeking new applications of IPL to meet the increasing needs of patients. OBJECTIVE: This review summarizes the development of IPL devices, discusses the current literature on the clinical application of IPL to increase our understanding of IPL, and provides guidance for broadening its clinical applications...
October 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27664793/the-celebration-of-40-years-of-structural-biology-at-aarhus-university-as-seen-through-the-eyes-of-a-translationalist
#15
William C Merrick
Over the past 50 years, both Brian Clark and I have worked on tRNA, Brian more successfully than I. Our common interests have established collaborations and the training of Aarhus University students in my laboratory. As part of my rejuvenation plan, I have returned to Aarhus and participated in teaching a course in protein synthesis about every five years, beginning in 1990. It has been through this close contact with both Brian and the numerous faculty of the structural biology group that I have been able to witness and appreciate the great strides they have made, both in building a world class department and in the ground breaking discoveries that went with them...
September 21, 2016: New Biotechnology
https://www.readbyqxmd.com/read/27659589/reconciling-concepts-of-time-and-person-centred-care-of-the-older-person-with-cognitive-impairment-in-the-acute-care-setting
#16
Carole Rushton, Anita Nilsson, David Edvardsson
The aim of this analysis was to examine the concept of time to rejuvenate and extend existing narratives of time within the nursing literature. In particular, we hope to promote a new trajectory in nursing research and practice which focuses on time and person-centred care, specifically of older people with cognitive impairment hospitalized in the acute care setting. We consider the explanatory power of concepts such as clock time, process time, fast care, slow care and time debt for elucidating the relationship between 'good care' and 'time use'...
October 2016: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/27651990/patchiness-of-forest-landscape-can-predict-species-distribution-better-than-abundance-the-case-of-a-forest-dwelling-passerine-the-short-toed-treecreeper-in-central-italy
#17
Marco Basile, Francesco Valerio, Rosario Balestrieri, Mario Posillico, Rodolfo Bucci, Tiziana Altea, Bruno De Cinti, Giorgio Matteucci
Environmental heterogeneity affects not only the distribution of a species but also its local abundance. High heterogeneity due to habitat alteration and fragmentation can influence the realized niche of a species, lowering habitat suitability as well as reducing local abundance. We investigate whether a relationship exists between habitat suitability and abundance and whether both are affected by fragmentation. Our aim was to assess the predictive power of such a relationship to derive advice for environmental management...
2016: PeerJ
https://www.readbyqxmd.com/read/27624682/hidden-lattice-instabilities-as-origin-of-the-conductive-interface-between-insulating-laalo3-and-srtio3
#18
P W Lee, V N Singh, G Y Guo, H-J Liu, J-C Lin, Y-H Chu, C H Chen, M-W Chu
The metallic interface between insulating LaAlO3 and SrTiO3 opens up the field of oxide electronics. With more than a decade of researches on this heterostructure, the origin of the interfacial conductivity, however, remains unsettled. Here we resolve this long-standing puzzle by atomic-scale observation of electron-gas formation for screening hidden lattice instabilities, rejuvenated near the interface by epitaxial strain. Using atomic-resolution imaging and electron spectroscopy, the generally accepted notions of polar catastrophe and cation intermixing for the metallic interface are discounted...
2016: Nature Communications
https://www.readbyqxmd.com/read/27612515/enhanced-expansion-and-sustained-inductive-function-of-skin-derived-precursor-cells-in-computer-controlled-stirred-suspension-bioreactors
#19
Natacha A Agabalyan, Breanna S Borys, Holly D Sparks, Kathryn Boon, Eko W Raharjo, Sepideh Abbasi, Michael S Kallos, Jeff Biernaskie
: : Endogenous dermal stem cells (DSCs) reside in the adult hair follicle mesenchyme and can be isolated and grown in vitro as self-renewing colonies called skin-derived precursors (SKPs). Following transplantation into skin, SKPs can generate new dermis and reconstitute the dermal papilla and connective tissue sheath, suggesting they could have important therapeutic value for the treatment of skin disease (alopecia) or injury. Controlled cell culture processes must be developed to efficiently and safely generate sufficient stem cell numbers for clinical use...
September 9, 2016: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/27591230/poor-embryo-development-in-post-ovulatory-in-vivo-aged-mouse-oocytes-is-associated-with-mitochondrial-dysfunction-but-mitochondrial-transfer-from-somatic-cells-is-not-sufficient-for-rejuvenation
#20
Hideki Igarashi, Toshifumi Takahashi, Hiroyuki Abe, Hiroshi Nakano, Osamu Nakajima, Satoru Nagase
STUDY QUESTION: Does in vivo aging of mouse oocytes affect mitochondrial function? SUMMARY ANSWER: Mitochondrial function was impaired in post-ovulatory in vivo-aged mouse oocytes and microinjection of somatic cell mitochondria did not rescue poor fertilization and embryonic development rates. WHAT IS KNOWN ALREADY: The mechanisms underlying the decline in oocyte quality associated with oocyte aging remain unknown, although studies have suggested that the decline is regulated by mitochondrial dysfunction...
October 2016: Human Reproduction
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