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Diet transcriptome

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https://www.readbyqxmd.com/read/28620217/secretory-laccase-1-in-bemisia-tabaci-med-is-involved-in-whitefly-plant-interaction
#1
Chun-Hong Yang, Jian-Yang Guo, Dong Chu, Tian-Bo Ding, Ke-Ke Wei, Deng-Fa Cheng, Fang-Hao Wan
The whitefly Bemisia tabaci is a phloem-feeding pest that lives predominantly on herbaceous species and causes serious damage to hosts. Whitefly saliva is thought to contain proteins that modulate plant defences and facilitate feeding. A predicted secreted protein, laccase 1 (LAC1), was found in the salivary gland transcriptome of B. tabaci and might be existed in the watery saliva of B. tabaci. As LAC1 has a potential role in detoxification of secondary plant compounds in insects, we speculated that it may participate in the insect's response to plant defences...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28611297/endogenous-il-33-has-no-effect-on-the-progression-of-fibrosis-during-experimental-steatohepatitis
#2
Philippe Vasseur, Sarah Dion, Aveline Filliol, Valentine Genet, Catherine Lucas-Clerc, Girard Jean-Philippe, Christine Silvain, Jean-Claude Lecron, Claire Piquet-Pellorce, Michel Samson
Interleukin (IL)-33 has been recently reported to be strongly pro-fibrogenic in various models of liver disease. Our aim was to study the role of endogenous IL-33 in a diet-induced model of steatohepatitis. IL-33 deficient mice and wild type (WT) littermates received a high-fat diet (HFD), or a standard diet for 12 weeks. The HFD-induced steatohepatitis was associated with an upregulation of IL-33 transcripts and protein. An insulin tolerance test revealed lower systemic insulin sensitivity in IL-33-/-HFD mice than in WT-HFD mice...
June 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28588501/genome-wide-characterization-and-expression-profiling-of-sugar-transporter-family-in-the-whitefly-bemisia-tabaci-gennadius-hemiptera-aleyrodidae
#3
Zezhong Yang, Jixing Xia, Huipeng Pan, Cheng Gong, Wen Xie, Zhaojiang Guo, Huixin Zheng, Xin Yang, Fengshan Yang, Qingjun Wu, Shaoli Wang, Youjun Zhang
Sugar transporters (STs) play pivotal roles in the growth, development, and stress responses of phloem-sucking insects, such as the whitefly, Bemisia tabaci. In this study, 137 sugar transporters (STs) were identified based on analysis of the genome and transcriptome of B. tabaci MEAM1. B. tabaci MEAM1 encodes a larger number of STs than other selected insects. Phylogenetic and molecular evolution analysis showed that the 137 STs formed three expanded clades and that the genes in Sternorrhyncha expanded clades had accelerated rates of evolution...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28580282/hepatic-gene-therapy-rescues-high-fat-diet-responses-in-circadian-clock-mutant-mice
#4
Judit Meyer-Kovac, Isa Kolbe, Lea Ehrhardt, Alexei Leliavski, Jana Husse, Gabriela Salinas, Thomas Lingner, Anthony H Tsang, Johanna L Barclay, Henrik Oster
OBJECTIVE: Circadian Clock gene mutant mice show dampened 24-h feeding rhythms and an increased sensitivity to high-fat diet (HFD) feeding. Restricting HFD access to the dark phase counteracts its obesogenic effect in wild-type mice. The extent to which altered feeding rhythms are causative for the obesogenic phenotype of Clock mutant mice, however, remains unknown. METHODS: Metabolic parameters of wild-type (WT) and Clock(Δ19) mutant mice (MT) were investigated under ad libitum and nighttime restricted HFD feeding...
June 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/28579762/prepartal-energy-intake-alters-blood-polymorphonuclear-leukocyte-transcriptome-during-the-peripartal-period-in-holstein-cows
#5
A Agrawal, M J Khan, D E Graugnard, M Vailati-Riboni, S L Rodriguez-Zas, J S Osorio, J J Loor
In the dairy industry, cow health and farmer profits depend on the balance between diet (ie, nutrient composition, daily intake) and metabolism. This is especially true during the transition period, where dramatic physiological changes foster vulnerability to immunosuppression, negative energy balance, and clinical and subclinical disorders. Using an Agilent microarray platform, this study examined changes in the transcriptome of bovine polymorphonuclear leukocytes (PMNLs) due to prepartal dietary intake. Holstein cows were fed a high-straw, control-energy diet (CON; NEL = 1...
2017: Bioinformatics and Biology Insights
https://www.readbyqxmd.com/read/28576296/biological-determinants-of-health-genes-microbes-and-metabolism-exemplars-of-nursing-science
#6
Erin P Ferranti, Ruth Grossmann, Angela Starkweather, Margaret Heitkemper
BACKGROUND: Increasingly, nurse scientists are incorporating "omics" measures (e.g., genomics, transcriptomics, proteomics, and metabolomics) in studies of biologic determinants of health and behavior. The role of omics in nursing science can be conceptualized in several ways: (a) as a portfolio of biological measures (biomarkers) to monitor individual risk, (b) as a set of combined data elements that can generate new knowledge based on large and complex patient data sets, (c) as baseline information that promotes health education and potentially personalized interventions, and (d) as a platform to understand how environmental parameters (e...
April 12, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28572628/adipose-tissue-dysfunction-as-a-central-mechanism-leading-to-dysmetabolic-obesity-triggered-by-chronic-exposure-to-p-p-dde
#7
Diogo Pestana, Diana Teixeira, Manuela Meireles, Cláudia Marques, Sónia Norberto, Carla Sá, Virgínia C Fernandes, Luísa Correia-Sá, Ana Faria, Luísa Guardão, João T Guimarães, Wendy N Cooper, Ionel Sandovici, Valentina F Domingues, Cristina Delerue-Matos, Rosário Monteiro, Miguel Constância, Conceição Calhau
Endocrine-disrupting chemicals such as p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE), are bioaccumulated in the adipose tissue (AT) and have been implicated in the obesity and diabetes epidemic. Thus, it is hypothesized that p,p'-DDE exposure could aggravate the harm of an obesogenic context. We explored the effects of 12 weeks exposure in male Wistar rats' metabolism and AT biology, assessing a range of metabolic, biochemical and histological parameters. p,p'-DDE -treatment exacerbated several of the metabolic syndrome-accompanying features induced by high-fat diet (HF), such as dyslipidaemia, glucose intolerance and hypertension...
June 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28545403/long-lasting-effect-of-obesity-on-skeletal-muscle-transcriptome
#8
Ilhem Messaoudi, Mithila Handu, Maham Rais, Suhas Sureshchandra, Byung S Park, Suzanne S Fei, Hollis Wright, Ashley E White, Ruhee Jain, Judy L Cameron, Kerri M Winters-Stone, Oleg Varlamov
BACKGROUND: Reduced physical activity and increased intake of calorically-dense diets are the main risk factors for obesity, glucose intolerance, and type 2 diabetes. Chronic overnutrition and hyperglycemia can alter gene expression, contributing to long-term obesity complications. While caloric restriction can reduce obesity and glucose intolerance, it is currently unknown whether it can effectively reprogram transcriptome to a pre-obesity level. The present study addressed this question by the preliminary examination of the transcriptional dynamics in skeletal muscle after exposure to overnutrition and following caloric restriction...
May 25, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28539586/whole-blood-transcriptome-analysis-reveals-potential-competition-in-metabolic-pathways-between-negative-energy-balance-and-response-to-inflammatory-challenge
#9
Juliette Bouvier-Muller, Charlotte Allain, Guillaume Tabouret, Francis Enjalbert, David Portes, Céline Noirot, Rachel Rupp, Gilles Foucras
Negative Energy Balance (NEB) is considered to increase susceptibility to mastitis. The objective of this study was to improve our understanding of the underlying mechanisms by comparing transcriptomic profiles following NEB and a concomitant mammary inflammation. Accordingly, we performed RNA-seq analysis of blood cells in energy-restricted ewes and control-diet ewes at four different time points before and after intra mammary challenge with phlogogenic ligands. Blood leucocytes responded to NEB by shutting down lipid-generating processes, including cholesterol and fatty acid synthesis, probably under transcriptional control of SREBF 1...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28537652/efficacy-and-safety-of-very-low-calorie-ketogenic-diet-a-double-blind-randomized-crossover-study
#10
C Colica, G Merra, A Gasbarrini, A De Lorenzo, G Cioccoloni, P Gualtieri, M A Perrone, S Bernardini, V Bernardo, L Di Renzo, M Marchetti
OBJECTIVE: To verify safety respect to weight loss, cardiometabolic diseases of short-term Very low-calorie ketogenic diets (VLCKDs, <800 kcal day-1). PATIENTS AND METHODS: Randomized cross-over trial with placebo. The study had no. 2 dietary treatment (DT), conducted in two arms: (1) VLCKD1 in which 50% of protein intake is replaced with synthetic amino acids; (2) VLCKD2 with placebo. The VLCKDs (<800 kcal day-1) were different in term of protein content and quality each arm lasted three weeks (wks)...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28535200/the-draft-genome-of-blunt-snout-bream-megalobrama-amblycephala-reveals-the-development-of-intermuscular-bone-and-adaptation-to-herbivorous-diet
#11
Han Liu, Chunhai Chen, Zexia Gao, Jiumeng Min, Yongming Gu, Jianbo Jian, Xiewu Jiang, Huimin Cai, Ingo Ebersberger, Meng Xu, Xinhui Zhang, Jianwei Chen, Wei Luo, Boxiang Chen, Junhui Chen, Hong Liu, Jiang Li, Ruifang Lai, Mingzhou Bai, Jin Wei, Shaokui Yi, Huanling Wang, Xiaojuan Cao, Xiaoyun Zhou, Yuhua Zhao, Kaijian Wei, Ruibin Yang, Bingnan Liu, Shancen Zhao, Xiaodong Fang, Manfred Schartl, Xueqiao Qian, Weimin Wang
Background: The blunt snout bream, Megalobrama amblycephala , is the economically most important cyprinid fish species. As an herbivore, it can be grown by eco-friendly and resource-conserving aquaculture. However, the large number of intermuscular bones in the trunk musculature is adverse to fish meat processing and consumption. Results: As a first towards optimizing this aquatic livestock, we present a 1.116-Gb draft genome of M. amblycephala , with 779.54 Mb anchored on 24 linkage groups...
May 23, 2017: GigaScience
https://www.readbyqxmd.com/read/28500613/functional-diets-modulate-lncrna-coding-rnas-and-gene-interactions-in-the-intestine-of-rainbow-trout-oncorhynchus-mykiss
#12
Gustavo Núñez-Acuña, Camille Détrée, Cristian Gallardo-Escárate, Ana Teresa Gonçalves
The advent of functional genomics has sparked the interest in inferring the function of non-coding regions from the transcriptome in non-model species. However, numerous biological processes remain understudied from this perspective, including intestinal immunity in farmed fish. The aim of this study was to infer long non-coding RNA (lncRNAs) expression profiles in rainbow trout (Oncorhynchus mykiss) fed for 30 days with functional diets based on pre- and probiotics. For this, whole transcriptome sequencing was conducted through Illumina technology, and lncRNAs were mined to evaluate transcriptional activity in conjunction with known protein sequences...
May 12, 2017: Marine Biotechnology
https://www.readbyqxmd.com/read/28486416/transcriptomics-and-the-mediterranean-diet-a-systematic-review
#13
REVIEW
Luis V Herrera-Marcos, José M Lou-Bonafonte, Carmen Arnal, María A Navarro, Jesús Osada
The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases and cancer and in decreasing overall mortality. Nowadays, transcriptomics is gaining particular relevance due to the existence of non-coding RNAs capable of regulating many biological processes. The present work describes a systematic review of current evidence supporting the influence of the Mediterranean diet on transcriptomes of different tissues in various experimental models. While information on regulatory RNA is very limited, they seem to contribute to the effect...
May 9, 2017: Nutrients
https://www.readbyqxmd.com/read/28482007/molecular-biomarkers-for-weight-control-in-obese-individuals-subjected-to-a-multi-phase-dietary-intervention
#14
Jennifer Bolton, Emilie Montastier, Jérôme Carayol, Sophie Bonnel, Lucile Mir, Marie-Adeline Marques, Arne Astrup, Wim Saris, Jason Iacovoni, Nathalie Villa-Vialaneix, Armand Valsesia, Dominique Langin, Nathalie Viguerie
Context: While calorie restriction has proven beneficial for weight loss, long-term weight control is variable between individuals. Objective: To identify biomarkers of successful weight control during a dietary intervention (DI). Design, Setting, and Participants: Adipose tissue (AT) transcriptomes were compared between 21 obese individuals that either maintained weight loss or regained weight during the DI. Results were validated on 310 individuals from the same study using RT-qPCR, and protein levels of potential circulating biomarkers measured by ELISA...
May 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28481231/zeolite-containing-mixture-supplementation-ameliorated-dextran-sodium-sulfate-induced-colitis-in-mice-by-suppressing-the-inflammatory-bowel-disease-pathway-and-improving-apoptosis-in-colon-mucosa
#15
Weida Lyu, Huijuan Jia, Chuanzong Deng, Kenji Saito, Seigo Yamada, Hisanori Kato
Inflammatory bowel disease (IBD) is induced by multiple environmental factors, and there is still no known treatment capable of curing the disease completely. We propose a zeolite-containing mixture (Hydryeast(®), HY)-a multi-component nutraceutical of which the main ingredients are Azumaceramics (mixture of zeolite and oyster shell burned under high temperature), citric acid, red rice yeast (monascus) and calcium stearate-as a nutraceutical intervention in IBD to ameliorate dextran sodium sulfate (DSS)-induced colitis...
May 6, 2017: Nutrients
https://www.readbyqxmd.com/read/28480144/transcriptome-assembly-and-candidate-genes-involved-in-nutritional-programming-in-the-swordtail-fish-xiphophorus-multilineatus
#16
Yuan Lu, Charlotte M Klimovich, Kalen Z Robeson, William Boswell, Oscar Ríos-Cardenas, Ronald B Walter, Molly R Morris
BACKGROUND: Nutritional programming takes place in early development. Variation in the quality and/or quantity of nutrients in early development can influence long-term health and viability. However, little is known about the mechanisms of nutritional programming. The live-bearing fish Xiphophorus multilineatus has the potential to be a new model for understanding these mechanisms, given prior evidence of nutritional programming influencing behavior and juvenile growth rate. We tested the hypotheses that nutritional programming would influence behaviors involved in energy homeostasis as well gene expression in X...
2017: PeerJ
https://www.readbyqxmd.com/read/28473973/salivary-diagnostics-in-pediatrics-applicability-translatability-and-limitations
#17
REVIEW
Mona Hassaneen, Jill L Maron
In the last decade, technological advances, combined with an improved appreciation of the ability of saliva to inform caregivers about both oral health and systemic disease, have led to the emergence of salivary diagnostic platforms. However, the majority of these assays have targeted diseases that more commonly affect the adult population, largely neglecting infants and children who arguably could benefit the most from non-invasive assessment tools for health monitoring. Gaining access into development, infection, and disease through comprehensive "omic" analyses of saliva could significantly improve care and enhance health access...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28455184/arabidopsis-glucosinolates-trigger-a-contrasting-transcriptomic-response-in-a-generalist-and-a-specialist-herbivore
#18
Fabian Schweizer, Hanna Heidel-Fischer, Heiko Vogel, Philippe Reymond
Phytophagous insects have to deal with toxic defense compounds from their host plants. Although it is known that insects have evolved genes and mechanisms to detoxify plant allochemicals, how specialist and generalist precisely respond to specific secondary metabolites at the molecular level is less understood. Here we studied the larval performance and transcriptome of the generalist moth Heliothis virescens and the specialist butterfly Pieris brassicae feeding on Arabidopsis thaliana genotypes with different glucosinolate (GS) levels...
April 26, 2017: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28454041/long-term-intake-of-a-high-protein-diet-increases-liver-triacylglycerol-deposition-pathways-and-hepatic-signs-of-injury-in-rats
#19
Rubén Díaz-Rúa, Jaap Keijer, Andreu Palou, Evert M van Schothorst, Paula Oliver
Intake of high-protein (HP) diets has increased over the last years, mainly due to their popularity for body weight control. Liver is the main organ handling ingested macronutrients and it is associated with the beginning of different pathologies. We aimed to deepen our knowledge on molecular pathways affected by long-term intake of an HP diet. We performed a transcriptome analysis on liver of rats chronically fed with a casein-rich HP diet and analyzed molecular parameters related to liver injury. Chronic increase in the dietary protein/carbohydrate ratio up-regulated processes related with amino acid uptake/metabolism and lipid synthesis, promoting a molecular environment indicative of hepatic triacylglycerol (TG) deposition...
April 19, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28434033/the-gut-microbiome-as-a-target-for-prevention-and-treatment-of-hyperglycaemia-in-type-2-diabetes-from-current-human-evidence-to-future-possibilities
#20
REVIEW
Louise Brunkwall, Marju Orho-Melander
The totality of microbial genomes in the gut exceeds the size of the human genome, having around 500-fold more genes that importantly complement our coding potential. Microbial genes are essential for key metabolic processes, such as the breakdown of indigestible dietary fibres to short-chain fatty acids, biosynthesis of amino acids and vitamins, and production of neurotransmitters and hormones. During the last decade, evidence has accumulated to support a role for gut microbiota (analysed from faecal samples) in glycaemic control and type 2 diabetes...
June 2017: Diabetologia
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