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https://www.readbyqxmd.com/read/28343247/development-of-a-qtl-environment-based-predictive-model-for-node-addition-rate-in-common-bean
#1
Li Zhang, Salvador A Gezan, C Eduardo Vallejos, James W Jones, Kenneth J Boote, Jose A Clavijo-Michelangeli, Mehul Bhakta, Juan M Osorno, Idupulapati Rao, Stephen Beebe, Elvin Roman-Paoli, Abiezer Gonzalez, James Beaver, Jaumer Ricaurte, Raphael Colbert, Melanie J Correll
This work reports the effects of the genetic makeup, the environment and the genotype by environment interactions for node addition rate in an RIL population of common bean. This information was used to build a predictive model for node addition rate. To select a plant genotype that will thrive in targeted environments it is critical to understand the genotype by environment interaction (GEI). In this study, multi-environment QTL analysis was used to characterize node addition rate (NAR, node day(- 1)) on the main stem of the common bean (Phaseolus vulgaris L)...
March 25, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28341646/cardiorespiratory-fitness-alters-the-influence-of-a-polygenic-risk-score-on-biomarkers-of-ad
#2
Stephanie A Schultz, Elizabeth A Boots, Burcu F Darst, Henrik Zetterberg, Kaj Blennow, Dorothy F Edwards, Rebecca L Koscik, Cynthia M Carlsson, Catherine L Gallagher, Barbara B Bendlin, Sanjay Asthana, Mark A Sager, Kirk J Hogan, Bruce P Hermann, Dane B Cook, Sterling C Johnson, Corinne D Engelman, Ozioma C Okonkwo
OBJECTIVE: To examine whether a polygenic risk score (PRS) derived from APOE4, CLU, and ABCA7 is associated with CSF biomarkers of Alzheimer disease (AD) pathology and whether higher cardiorespiratory fitness (CRF) modifies the association between the PRS and CSF biomarkers. METHODS: Ninety-five individuals from the Wisconsin Registry for Alzheimer's Prevention were included in these cross-sectional analyses. They were genotyped for APOE4, CLU, and ABCA7, from which a PRS was calculated for each participant...
March 24, 2017: Neurology
https://www.readbyqxmd.com/read/28332574/natural-variation-in-ctb4a-enhances-rice-adaptation-to-cold-habitats
#3
Zhanying Zhang, Jinjie Li, Yinghua Pan, Jilong Li, Lei Zhou, Hongli Shi, Yawen Zeng, Haifeng Guo, Shuming Yang, Weiwei Zheng, Jianping Yu, Xingming Sun, Gangling Li, Yanglin Ding, Liang Ma, Shiquan Shen, Luyuan Dai, Hongliang Zhang, Shuhua Yang, Yan Guo, Zichao Li
Low temperature is a major factor limiting rice productivity and geographical distribution. Improved cold tolerance and expanded cultivation to high-altitude or high-latitude regions would help meet growing rice demand. Here we explored a QTL for cold tolerance and cloned the gene, CTB4a (cold tolerance at booting stage), encoding a conserved leucine-rich repeat receptor-like kinase. We show that different CTB4a alleles confer distinct levels of cold tolerance and selection for variation in the CTB4a promoter region has occurred on the basis of environmental temperature...
March 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28329467/unna-boot-central-gauze-technique-for-chronic-venous-leg-ulcers
#4
Anne L Gao, Justin G Cole, William V Stoecker
BACKGROUND: Venous leg ulcers generally take manyweeks to heal. Novel therapies that shorten healingtime and require less complex care are needed. PURPOSE: The purpose of this report is to presenta pilot study for a new method that can result ina faster healing time for venous leg ulcers usinginexpensive materials. METHODS: A central-gauzeprotocol was developed as described here. A three-ply gauze sponge was placed in the center of theulcer, allowing a peripheral 3-5 mm rim of ulcer toremain exposed...
January 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28327406/serum-non-hdl-cholesterol-to-apolipoprotein-b-ratio-as-a-screening-test-for-familial-dysbetalipoproteinaemia-type-iii-hyperlipidaemia-in-patients-with-mixed-hyperlipidaemia
#5
Christopher Boot, Elizabeth Holmes, R Dermot G Neely
No abstract text is available yet for this article.
December 2016: Atherosclerosis
https://www.readbyqxmd.com/read/28321186/brain-activity-during-mental-imagery-of-gait-versus-gait-like-plantar-stimulation-a-novel-combined-functional-mri-paradigm-to-better-understand-cerebral-gait-control
#6
Matthieu Labriffe, Cédric Annweiler, Liubov E Amirova, Guillemette Gauquelin-Koch, Aram Ter Minassian, Louis-Marie Leiber, Olivier Beauchet, Marc-Antoine Custaud, Mickaël Dinomais
Human locomotion is a complex sensorimotor behavior whose central control remains difficult to explore using neuroimaging method due to technical constraints, notably the impossibility to walk with a scanner on the head and/or to walk for real inside current scanners. The aim of this functional Magnetic Resonance Imaging (fMRI) study was to analyze interactions between two paradigms to investigate the brain gait control network: (1) mental imagery of gait, and (2) passive mechanical stimulation of the plantar surface of the foot with the Korvit boots...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28303535/hyaluronic-acid-based-hydrogel-coating-does-not-affect-bone-apposition-at-the-implant-surface-in-a-rabbit-model
#7
W Boot, D Gawlitta, P G J Nikkels, B Pouran, M H P van Rijen, W J A Dhert, H Ch Vogely
BACKGROUND: Uncemented orthopaedic implants rely on the bone-implant interface to provide stability, therefore it is essential that a coating does not interfere with the bone-forming processes occurring at the implant interface. In addition, local application of high concentrations of antibiotics for prophylaxis or treatment of infection may be toxic for osteoblasts and could impair bone growth. QUESTIONS/PURPOSES: In this animal study, we investigated the effect of a commercially available hydrogel, either unloaded or loaded with 2% vancomycin...
March 16, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28301246/persistence-of-highly-pathogenic-and-low-pathogenic-avian-influenza-viruses-in-footbaths-and-poultry-manure
#8
R Hauck, B Crossley, D Rejmanek, H Zhou, R A Gallardo
A questionnaire was designed in order to gather information about bedding material and footbath preparation and maintenance in different productive units across the state of California.This information was used to plan two experiments. In the first experiment, we tested the effectiveness of footbaths in inactivating highly pathogenic (HP) and low pathogenic (LP) avian influenza viruses (AIVs) on rubber boots. Surprisingly, quaternary ammonia- and quaternary ammonia + glutaraldehyde-based footbaths were not able to eliminate live HPAIV (H5N8) and LPAIV (H6N2) particles on boots, while a chlorine-based granulated disinfectant was able to destroy the virus at contact...
March 2017: Avian Diseases
https://www.readbyqxmd.com/read/28296971/retention-and-sustainability-of-community-based-health-volunteers-activities-a-qualitative-study-in-rural-northern-ghana
#9
Samuel Chatio, Patricia Akweongo
BACKGROUND: The shortage of formal health workers has led to the utilization of Community-Based Health Volunteers (CBHV) to provide health care services to people especially in rural and neglected communities. Community-based health volunteers have been effective partners in health care delivery at the community level for many years. The challenge is how to retain these volunteers and also sustain their activities. This study explored factors affecting retention and sustainability of community-based health volunteers' activities in a rural setting in Northern Ghana...
2017: PloS One
https://www.readbyqxmd.com/read/28293687/melanoma-in-segmental-naevus-spilus-a-case-series-and-literature-review
#10
Monica C T Boot-Bloemen, Wim J A de Kort, Lidwine M T van der Spek-Keijser, Nicole A Kukutsch
is missing (Short communication).
March 15, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28293467/relationships-between-cardiorespiratory-fitness-hippocampal-volume-and-episodic-memory-in-a-population-at-risk-for-alzheimer-s-disease
#11
Ryan J Dougherty, Stephanie A Schultz, Elizabeth A Boots, Laura D Ellingson, Jacob D Meyer, Stephanie Van Riper, Aaron J Stegner, Dorothy F Edwards, Jennifer M Oh, Jean Einerson, Claudia E Korcarz, Rebecca L Koscik, Maritza N Dowling, Catherine L Gallagher, Cynthia M Carlsson, Howard A Rowley, Barbara B Bendlin, Sanjay Asthana, Bruce P Hermann, Mark A Sager, James H Stein, Sterling C Johnson, Ozioma C Okonkwo, Dane B Cook
INTRODUCTION: Cardiorespiratory fitness (CRF) has been shown to be related to brain health in older adults. In individuals at risk for developing Alzheimer's disease (AD), CRF may be a modifiable risk factor that could attenuate anticipated declines in brain volume and episodic memory. The objective of this study was to determine the association between CRF and both hippocampal volume and episodic memory in a cohort of cognitively healthy older adults with familial and/or genetic risk for Alzheimer's disease (AD)...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28293188/evidence-for-narrow-transfer-after-short-term-cognitive-training-in-older-adults
#12
Dustin J Souders, Walter R Boot, Kenneth Blocker, Thomas Vitale, Nelson A Roque, Neil Charness
The degree to which "brain training" can improve general cognition, resulting in improved performance on tasks dissimilar from the trained tasks (transfer of training), is a controversial topic. Here, we tested the degree to which cognitive training, in the form of gamified training activities that have demonstrated some degree of success in the past, might result in broad transfer. Sixty older adults were randomly assigned to a gamified cognitive training intervention or to an active control condition that involved playing word and number puzzle games...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28290931/prophylactic-ankle-bracing-in-military-settings-a-review-of-the-literature
#13
Thomas M Newman, Michael R Gay, W E Buckley
BACKGROUND: Within athletics and the military, ankle sprains are one of the most common injuries with the potential for long-term functional deficits. Incidence rates for ankle sprains within the military are one of the leading causes of limited duty days, especially during basic combat training, parachute training exercises, and in cadet populations. In 2008, the Department of Defense U.S. Army Center for Health Promotion and Preventative Medicine report recommended that military personnel should wear semirigid ankle braces during parachuting, basketball, soccer, and other similar high-risk activities to reduce ankle sprain injuries...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28282226/a-quantitative-real-time-pcr-approach-for-assessing-campylobacter-jejuni-and-campylobacter-coli-colonization-in-broiler-herds
#14
Katrin Haas, Gudrun Overesch, Peter Kuhnert
Human campylobacteriosis is a major public health concern in developed countries, with Campylobacter jejuni and Campylobacter coli from poultry recognized as the main source of human infection. Identification of Campylobacter-positive broiler herds before slaughter is essential for implementing measures to avoid carryover of pathogens via the slaughter process into the food chain. However, appropriate methods that have been validated for testing poultry flocks antemortem are lacking for Campylobacter. A quantitative real-time PCR (qPCR) that allows simultaneous detection and quantification of C...
March 10, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28275593/intellectual-disability-and-assistive-technology-opening-the-gate-wider
#15
Fleur Heleen Boot, John Dinsmore, Chapal Khasnabis, Malcolm MacLachlan
The World Health Organization has launched a program to promote Global Cooperation on Assistive Technology (GATE). The objective of the GATE program is to improve access to high quality, affordable assistive technology for people with varying disabilities, diseases, and age-related conditions. As a first step, GATE has developed the assistive products list, a list of priority assistive products based on addressing the greatest need at population level. A specific group of people who can benefit from user appropriate assistive technology are people with intellectual disabilities...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28270305/carboxymethyl-cellulose-trichloroacetic-acid-and-unna-boot-for-healing-venous-ulcers-a-comparative-study-of-their-efficacy-and-socioeconomic-impact
#16
Sueli Carneiro, Virginia Januário, Maria Leide W Oliveira, Maria Luiza de Oliveira Teixeira, Solange Maciel, João Carlos Macedo, Marcia Ramos-E-Silva
Chronic ulcers are defined as a breakdown of the long-term cutaneous barrier or frequent recurrence of breakdowns. Dressings are a form of treatment and, in view of the variety and high cost of the products on the market, three agents were selected for this investigation, regarding their efficacy and cost/benefit ratio. The objective of the investigation was to evaluate and compare the efficacy, costs, and benefits of carboxymethylcellulose in paste at 20% (CMC 20%), trichloroacetic acid at 90% (TCA 90%), and Unna boot for treatment of chronic venous ulcers...
2017: Skinmed
https://www.readbyqxmd.com/read/28263630/individual-differences-in-automatic-semantic-priming
#17
Sally Andrews, Steson Lo, Violet Xia
This research investigated whether masked semantic priming in a semantic categorization task that required classification of words as animals or nonanimals was modulated by individual differences in lexical proficiency. A sample of 89 skilled readers, assessed on reading comprehension, vocabulary and spelling ability, classified target words preceded by brief (50 ms) masked primes that were either congruent or incongruent with the category of the target. Congruent primes were also selected to be either high (e...
March 6, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28250797/changes-in-peripheral-immune-cell-numbers-and-functions-in-octogenarian-walkers-an-acute-exercise-study
#18
Kornelis S M van der Geest, Qi Wang, Thijs M H Eijsvogels, Hans J P Koenen, Irma Joosten, Elisabeth Brouwer, Maria T E Hopman, Joannes F M Jacobs, Annemieke M H Boots
BACKGROUND: Age-related changes of the immune system, termed immunosenescence, may underlie the increased risk of infections and morbidity in the elderly. Little is known about the effects of acute exercise on peripheral immune parameters in octogenarians. Therefore, we investigated acute exercise-induced changes in phenotype and function of the immune system in octogenarians participating in the 2013 edition of the Nijmegen Four Days Marches. Blood sampling was performed at baseline and immediately after 4 days of the walking exercise (30 km/day)...
2017: Immunity & Ageing: I & A
https://www.readbyqxmd.com/read/28245572/phase-compensation-sensor-for-ranging-consistency-in-inter-satellite-links-of-navigation-constellation
#19
Zhijun Meng, Jun Yang, Xiye Guo, Mei Hu
Theperformanceoftheglobalnavigationsatellitesystem(GNSS)canbeenhancedsignificantly by introducing the inter-satellite links (ISL) of a navigation constellation. In particular, the improvement of the position, velocity, and time accuracy, and the realization of autonomous functions require the ISL distance measurement data as the original input. For building a high-performance ISL, the ranging consistency between navigation satellites becomes a crucial problem to be addressed. Considering the frequency aging drift and the relativistic effect of the navigation satellite, the frequency and phase adjustment (FPA) instructions for the 10...
February 24, 2017: Sensors
https://www.readbyqxmd.com/read/28238931/effect-of-interleukin-il-8-on-benzo-a-pyrene-metabolism-and-dna-damage-in-human-lung-epithelial-cells
#20
Q Shi, A W Boots, L Maas, C Veith, K van Kuijk, G R Haenen, R W Godschalk, F J Van Schooten
It has been well established that inflammation and concurrent mutagenic exposures drive the carcinogenic process in a synergistic way. To elucidate the role of the inflammatory cytokine IL-8 in this process, we studied its effect on the activation and deactivation of the chemical mutagen benzo[a]pyrene B[a]P in the immortalized pulmonary BEAS-2B cell line. After 24h incubation with B[a]P in the presence or absence of IL-8, the B[a]P induced cytochrome P450 1A1 and 1B1 (CYP1A1 and CYP1B1) gene expression and CYP1A1 enzyme activity was significantly higher in the presence of the cytokine...
April 15, 2017: Toxicology
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