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Wudan Yan
In early September 2017, when the rains from Hurricane Harvey finally subsided in Houston, Texas, Seth Pedersen loaded up his pickup truck with sample collection kits, waders, rubber boots, buckets, and a small aluminum fishing boat. On that particular day, Pedersen, a second-year graduate student in environmental engineering at Rice University, was-along with a fellow graduate student-on a mission to test the water in homes flooded by Hurricane Harvey. He was looking specifically for E. coli bacteria, chemicals, heavy metals, and other pathogens (Figure 1)...
March 2018: IEEE Pulse
Kimberly A Bagley, Sarah E Dunn, Eliseu Y Chuang, Victoria J Dorr, Julie A Thompson, Sophia K Smith
BACKGROUND: A community hospital combined its medical and surgical patients with cancer on one unit, which resulted in nurses not trained in oncology caring for this patient population. OBJECTIVES: The Oncology Intensives Initiative (ONCii) involved the (a) design and implementation of a daylong didactic boot camp class and a four-hour simulation session and (b) the examination of nurses' worries, attitudes, self-efficacy, and perception of interdisciplinary teamwork...
April 1, 2018: Clinical Journal of Oncology Nursing
Rob R H van den Brom, Kornelis S M van der Geest, Elisabeth Brouwer, Geke A P Hospers, Annemieke M H Boots
The biological behavior of melanoma is unfavorable in the elderly when compared to young subjects. We hypothesized that differences in T-cell responses might underlie the distinct behavior of melanoma in young and old melanoma patients. Therefore, we investigated the circulating T-cell compartment of 34 patients with metastatic melanoma and 42 controls, which were classified as either young or old. Absolute numbers of CD4+ T cells were decreased in young and old melanoma patients when compared to the age-matched control groups...
March 15, 2018: Cancer Immunology, Immunotherapy: CII
Ahmad Khobrani, Nirali H Patel, Richard L George, Neil L McNinch, Rami A Ahmed
Trauma is a leading cause of morbidity and mortality in infants and children worldwide. Trauma education is one of the most commonly reported deficiencies in pediatric emergency medicine (PEM) training. In this study, we describe the creation of a pediatric trauma boot camp in which trainees' basic knowledge, level of confidence, teamwork, and communication skills are assessed. The primary goal of this pilot study was to create a simulation-based pediatric trauma curriculum for PEM fellows and emergency medicine residents utilizing Kern's curricular conceptual framework...
2018: Emergency Medicine International
Samantha B Boots, Marika Tiggemann, Nadia Corsini
The aim of this study was to investigate maternal feeding strategies as prospective predictors of young children's snack intake. Participants were 252 mothers of children aged 3-11 years old who completed questionnaire measures of parent feeding strategies (Restriction and Covert Control) and reported on their child's healthy and unhealthy snack intake at two time points separated by three years. Longitudinal regression models showed no prediction of healthy snack food intake. However, Time 1 parental restrictive feeding predicted greater unhealthy snack intake at Time 2, while Time 1 covert feeding strategies predicted lower unhealthy snack intake at Time 2...
March 10, 2018: Appetite
Kristen M Brown, Shawna S Mudd, Elizabeth A Hunt, Julianne S Perretta, Nicole A Shilkofski, J Wesley Diddle, Gregory Yurasek, Melania Bembea, Jordan Duval-Arnould, Kristen Nelson McMillan
OBJECTIVES: Assess the effect of a simulation "boot camp" on the ability of pediatric nurse practitioners to identify and treat a low cardiac output state in postoperative patients with congenital heart disease. Additionally, assess the pediatric nurse practitioners' confidence and satisfaction with simulation training. DESIGN: Prospective pre/post interventional pilot study. SETTING: University simulation center. SUBJECTS: Thirty acute care pediatric nurse practitioners from 13 academic medical centers in North America...
March 10, 2018: Pediatric Critical Care Medicine
Pisit Suntaravitun, Amornrat Dokmaikaw
Intestinal parasitic infections remain a major public health problem in many parts of Thailand, particularly in rural areas. This study aimed to determine the prevalence of intestinal parasitic infections and associated risk factors among the people living in Huai Sai sub-district, Bang Khla district, Chachoengsao Province, central Thailand. A cross-sectional survey was carried out from June 2017 to August 2017 which included a total of 224 participants. Stool samples were examined using a simple direct smear and formalin ethyl acetate concentration technique...
February 2018: Korean Journal of Parasitology
M Forouhan, K Mori, R P Boot-Handford
Whilst the role of ATF6α in modulating the unfolded protein response (UPR) has been well documented, the function of its paralogue ATF6β is less well understood. Using knockdown in cell culture and gene ablation in mice we have directly compared the roles of ATF6α & β in responding to the increased ER stress induced by mutant forms of type X collagen that cause the ER stress-associated metaphyseal chondrodysplasia type Schmid (MCDS). ATF6α more efficiently deals with the disease-associated ER stress in the absence of ATF6β and conversely, ATF6β is less effective in the absence of ATF6α...
March 6, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
Naing T Thet, Laura Wallace, Anne Wibaux, Nick Boote, A Toby A Jenkins
It is becoming increasingly accepted that to understand and model the bacterial colonization and infection of abiotic surfaces requires the use of a biofilm model. There are many bacterial colonizations by at least two primary species, however this is difficult to model in vitro. This study reports the development of a simple mixed-species biofilm model using strains of two clinically significant bacteria: Staphylococcus aureus and Pseudomonas aeruginosa grown on nanoporous polycarbonate membranes on nutrient agar support...
March 8, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Rebeca Hid Cadena, Wayel H Abdulahad, G A P Hospers, T T Wind, Annemieke M H Boots, Peter Heeringa, Elisabeth Brouwer
Age-associated changes in the immune system including alterations in surface protein expression are thought to contribute to an increased susceptibility for autoimmune diseases. The balance between the expression of coinhibitory and costimulatory surface protein molecules, also known as immune checkpoint molecules, is crucial in fine-tuning the immune response and preventing autoimmunity. The activation of specific inhibitory signaling pathways allows cancer cells to evade recognition and destruction by the host immune system...
2018: Frontiers in Immunology
Christopher J Udell, Julie L Ruddy, Philip M Procento
Introduction: US Navy recruits who have injuries preventing them from participating in intense physical conditioning are pulled out of boot camp training and receive treatment that includes daily physical therapy, pain medications, and psychoeducational groups. Graduation from boot camp for these recruits requires not only recovering from their injuries but also passing a required Physical Fitness Assessment consisting of a timed 1.5-mile run, curl-ups, and push-ups. About 50-60% of these recruits will eventually be separated out and sent home...
March 6, 2018: Military Medicine
Xuexin Xu, Yinghua Zhang, Jinpeng Li, Meng Zhang, Xiaonan Zhou, Shunli Zhou, Zhimin Wang
Improving winter wheat grain yield and water use efficiency (WUE) with minimum irrigation is very important for ensuring agricultural and ecological sustainability in the Northern China Plain (NCP). A three-year field experiment was conducted to determine how single irrigation can improve grain yield and WUE by manipulating the "sink-source" relationships. To achieve this, no-irrigation after sowing (W0) as a control, and five single irrigation treatments after sowing (75 mm of each irrigation) were established...
2018: PloS One
Joshua D Niforatos
The hallways of the Emergency Department are filled with patients during influenza season. Our patient is rushed to imaging with work-boots left-behind as his placeholder. This article is protected by copyright. All rights reserved.
March 6, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Jose A Blanco, Gemma Slater, Jitendra Mangwani
The incidence of venous thromboembolic (VTE) events (deep vein thrombophlebitis [DVT] or pulmonary embolism [PE]) in foot and ankle trauma has been low, and the risk/benefit ratio associated with chemoprophylaxis is controversial. We compared the 90-day incidence of VTE events in 3 cohorts: group 1, tendo-Achillis (TA) ruptures managed with full weightbearing in a walker boot; group 2, ankle fractures immobilized non-weightbearing in a below-the-knee cast; and group 3, ankle fractures managed surgically, followed by non-weightbearing in a below-the-knee cast...
March 1, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Celia Herrera-Rincon, Michael Levin
A recent study in Xenopus laevis embryos showed that the very early brain has important functions long before behavior. While the nascent brain is being constructed, it is required for normal patterning of the muscle and peripheral nerve networks, including those far away from the head. In addition to providing important developmental signals to remote tissues in normal embryogenesis, its presence is also able to render harmless exposure to specific chemicals that normally act as teratogens. These activities of the early brain can be partially compensated for in a brainless embryo by experimental modulation of neurotransmitter and ion channel signaling...
2018: Communicative & Integrative Biology
Cécile R L Boot, Astrid de Wind, Myrthe van Vilsteren, Allard J van der Beek, Dirkjan van Schaardenburg, Johannes R Anema
OBJECTIVE: Rheumatoid arthritis (RA) affects adults of working age and leads to productivity losses because of presenteeism that results from limitations while at work. The aim of our study was to gain insight into disease-related factors, general health, and work characteristics as predictors of presenteeism in workers with RA. METHODS: Workers with RA (n = 150) recruited by rheumatologists completed questionnaires at baseline and after 1 year. Medical information was retrieved from patient records...
March 1, 2018: Journal of Rheumatology
Franz Konstantin Fuss, Peter Düking, Yehuda Weizman
This paper provides the evidence of a sweet spot on the boot/foot as well as the method for detecting it with a wearable pressure sensitive device. This study confirmed the hypothesized existence of sweet and dead spots on a soccer boot or foot when kicking a ball. For a stationary curved kick, kicking the ball at the sweet spot maximized the probability of scoring a goal (58-86%), whereas having the impact point at the dead zone minimized the probability (11-22%). The sweet spot was found based on hypothesized favorable parameter ranges (center of pressure in x/y-directions and/or peak impact force) and the dead zone based on hypothesized unfavorable parameter ranges...
2018: Frontiers in Physiology
Meagan Cusack, Ann Elizabeth Montgomery
Though the U.S. Departments of Housing and Urban Development (HUD) and Veterans Affairs (VA) supportive housing (HUD-VASH) program endeavors to address barriers to Veterans accessing and maintaining housing, participants report challenges that lead to program exits. This study aims to understand participants' views on the factors contributing to their exits from HUD-VASH, as well as how program staff may respond to challenges. This mixed methods study includes four sources of data: (1) surveys with Veterans, (2) semi-structured interviews with a subsample of surveyed Veterans, (3) Veterans' administrative data from VA electronic data systems, and (4) focus groups with staff from local public housing authorities and VA case management teams...
February 26, 2018: Social Work in Health Care
Samaneh Abbasi, Manoochehr Makvandi, Ali Teimoori, Alireza Samarbaf-Zadeh
BACKGROUND: Echovirus 6 (E6), is one of the main enteroviral serotypes, was initially isolated from patients with aseptic meningitis (AM) and is a major cause of hospitalization among children and adults worldwide. METHODS: A cerebrospinal fluid (CSF) sample was collected from patient with clinically suspected aseptic meningitis (AM) in August 2011. Following detection of a virus and subsequent virus serotyping, the whole genome sequence was determined. The sequence of the VP1 region of the isolated strain E6 RA/E6/Ahvaz/Iran/2011 showed 79% (>75%) nucleotide and 94% (>85%) amino acid homology with prototype strain D'Amori...
February 20, 2018: Journal of the Chinese Medical Association: JCMA
Noellie Gay, Alexandre Leclaire, Morgane Laval, Guillaume Miltgen, Maël Jégo, Ramin Stéphane, Julien Jaubert, Olivier Belmonte, Eric Cardinale
In South Western Indian ocean (IO), Extended-Spectrum β-Lactamase producing Enterobacteriaceae (ESBL-E) are a main public health issue. In livestock, ESBL-E burden was unknown. The aim of this study was estimating the prevalence of ESBL-E on commercial farms in Reunion, Mayotte and Madagascar and genes involved. Secondly, risk factors of ESBL-E occurrence in broiler, beef cattle and pig farms were explored. In 2016-2017, commercial farms were sampled using boot swabs and samples stored at 4 °C before microbiological analysis for phenotypical ESBL-E and gene characterization...
February 23, 2018: Veterinary Sciences
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