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https://www.readbyqxmd.com/read/28531869/a-rare-case-of-subacute-appendicitis-actinomycosis-as-the-final-pathology-reports-a-case-report-and-literature-review
#1
G A Gómez-Torres, O S Ortega-Gárcia, E G Gutierrez-López, C A Carballido-Murguía, J A Flores-Rios, C R López-Lizarraga, C A Bautista López, C F Ploneda-Valencia
INTRODUCTION: Acute appendicitis is the most common indication for an emergency abdominal surgery in the world, with a lifetime incidence of around 10%. Actinomycetes are the etiology of appendicitis in only 0.02%-0.06%, having as the final pathology report a chronic inflammatory response; less than 10% of the cases are diagnosed before surgery. Here, we present the case of a subacute appendicitis secondary to actinomycosis. CASE REPORT: A 39-year-old male presented with a twelve-day evolution of intermittent abdominal pain in the right lower quadrant, treated at the beginning with ciprofloxacin and urinary analgesic...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28531836/trauma-exposure-incident-psychiatric-disorders-and-disorder-transitions-in-a-longitudinal-population-representative-sample
#2
Kate Walsh, Katie A McLaughlin, Ava Hamilton, Katherine M Keyes
Heterotypic continuity, whereby individuals transition from one disorder to another, is common; however, longitudinal studies examining transdiagnostic predictors of heterotypic continuity are lacking. The current study examined whether trauma exposure during childhood (maltreatment) and adulthood (interpersonal and non-interpersonal trauma) is associated with heterotypic continuity in a national sample. Men and women (N = 34,653) who participated in Waves 1 (2001-2002) and 2 (2004-2005) of the National Survey of Alcohol and Related Conditions (NESARC) completed face-to-face interviews about trauma exposure and psychopathology...
May 5, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28531791/an-innovative-brioche-enriched-in-protein-and-energy-improves-the-nutritional-status-of-malnourished-nursing-home-residents-compared-to-oral-nutritional-supplement-and-usual-breakfast-farine-project
#3
Virginie Van Wymelbeke, Laurent Brondel, Francis Bon, Isabelle Martin-Pfitzenmeyer, Patrick Manckoundia
BACKGROUND & AIMS: To compare the effects of a 12-week nutritional intervention, in which an innovative protein-and-energy-enriched brioche, an oral nutritional supplement or a usual breakfast were eaten, on food intake and nutritional status in nursing home residents. DESIGN: Three-armed, multicentre, controlled trial. SETTING: Eight nursing homes in Burgundy, France. PARTICIPANTS: Sixty-eight malnourished participants aged between 70 and 99 years old...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531780/vitamin-d-status-and-the-effects-of-oral-vitamin-d-treatment-in-children-with-vitiligo-a-prospective-study
#4
Gülay Karagüzel, Nil P Sakarya, Sevgi Bahadır, Selçuk Yaman, Ayşenur Ökten
BACKGROUND & AIMS: Vitiligo is a pigmentary disorder and autoimmune pathogenesis seems most likely. Decreased vitamin D levels have been related to several autoimmune diseases. Little is known about the association of vitiligo and vitamin D. We aimed to evaluate serum 25-hydroxyvitamin D [25(OH)D] levels in children with vitiligo and to determine the efficacy of oral vitamin D therapy on the repigmentation of vitamin D deficient patients. METHODS: Thirty patients aged 6-17 years with vitiligo and 30 sex- and age-matched apparently healthy controls were included in this prospective study...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28530603/modelling-of-the-effect-of-selenium-fertilization-on-the-content-of-bioactive-compounds-in-broccoli-heads
#5
Andrea Mahn
Selenium (Se) exerts many effects beneficial to health. Broccoli is a Se-hyperaccumulator plant, with Se-fertilization increasing its potential as a functional food. We studied the effect of dose, and the developmental stage at the beginning of Se-fortification, on antioxidant capacity, phenolics, glucosinolates, sulphoraphane, Se-methyl selenocysteine and myrosinase in broccoli. Se-fortification decreased the antioxidant properties and sulphur-containing compounds, but increased Se-methyl-selenocysteine content...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28530503/comparison-of-self-selected-walking-speeds-and-walking-speed-variability-when-data-are-collected-during-repeated-discrete-trials-and-during-continuous-walking
#6
Marcus J Brown, Laura A Hutchinson, Michael J Rainbow, Kevin J Deluzio, Alan R De Asha
A typical gait analysis data collection consists of a series of discrete trials, where a participant initiates gait, walks through a motion capture volume, and then terminates gait. This is not a normal 'everyday' gait pattern, yet measurements are considered representative of normal walking. However, walking speed, a global descriptor of gait quality that can affect joint kinematics and kinetics, may be different during discrete trials, compared to continuous walking. Therefore, the purpose of this study was to investigate the effect of continuous walking versus discrete trials on walking speed and walking speed variability...
May 22, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28530411/the-legacy-of-early-childhood-violence-exposure-to-adulthood-intimate-partner-violence-variable-and-person-oriented-evidence
#7
Angela J Narayan, Madelyn H Labella, Michelle M Englund, Elizabeth A Carlson, Byron Egeland
This study examined prospective pathways from exposure to interparental violence (EIPV) during infancy (ages 0-24 months) and toddlerhood/preschool (ages 25-64 months) to intimate partner violence (IPV) perpetration and victimization in adulthood (ages 23, 26, and 32 years) using 2 complementary approaches. Building on past findings, a variable-oriented approach was used to examine the effects of developmental timing of EIPV in infancy versus toddlerhood/preschool to IPV involvement in early adulthood, at age 23 years...
May 22, 2017: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/28530321/-the-effect-of-down-syndrome-on-teeth-and-jaws-development-the-first-case-report-on-dental-implants-with-15-years-follow-up
#8
Uri Zilberman
Down syndrome presents dentists with several treatment problems due to hereditary olygodontia of permanent teeth, abnormal development of the midface causing small maxilla and class III occlusion, abnormal mineralization of teeth, reduced bone density and hypotony. The challenge of replacing missing permanent teeth was the trigger for the development of dental implants some 30 years ago. However, the abnormal development of jaw bones and the reverse occlusion caused concerns in the dental community regarding the possibility of using dental implants in Down syndrome patients...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28530203/eit-based-pulsatile-impedance-monitoring-during-spontaneous-breathing-in-cystic-fibrosis
#9
Sabine Krueger-Ziolek, Benjamin Schullcke, Bo Gong, Ullrich Müller-Lisse, Knut Moeller
OBJECTIVE: Evaluating the lung function in patients with obstructive lung disease by electrical impedance tomography (EIT) usually requires breathing maneuvers containing deep inspirations and forced expirations. Since these maneuvers strongly depend on the patient's co-operation and health status, normal tidal breathing was investigated in an attempt to develop continuous maneuver-free measurements. APPROACH: Ventilation related and pulsatile impedance changes were systematically analyzed during normal tidal breathing in 12 cystic fibrosis (CF) patients and 12 lung-healthy controls (HL)...
June 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28530036/living-and-dying-to-be-counted-what-we-know-about-the-epidemiology-of-the-global-adolescent-hiv-epidemic
#10
Amy L Slogrove, Mary Mahy, Alice Armstrong, Mary-Ann Davies
INTRODUCTION: With increasing survival of vertically HIV-infected children and ongoing new horizontal HIV infections, the population of adolescents (age 10-19 years) living with HIV is increasing. This review aims to describe the epidemiology of the adolescent HIV epidemic and the ability of national monitoring systems to measure outcomes in HIV-infected adolescents through the adolescent transition to adulthood. METHODS: Differences in global trends between younger (age 10-14 years) and older (age 15-19 years) adolescents in key epidemic indicators are interrogated using 2016 UNAIDS estimates...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28530019/men1-in-children-and-adolescents-data-from-patients-of-a-regional-referral-center-for-hereditary-endocrine-tumors
#11
Letizia Vannucci, Francesca Marini, Francesca Giusti, Simone Ciuffi, Francesco Tonelli, Maria Luisa Brandi
PURPOSE: To retrospectively evaluate the age of onset of MEN1-associated lesions in a group of affected children and adolescents and to compare the clinical features of our series with the evidence derived from the literature. METHODS: The study population consisted of 22 Italian children and adolescents (age 6-31 years at the time of the inclusion in this study) all with a clinical and/or a genetic diagnosis of MEN1 performed before the age of 16 who have been followed-up regularly from 1998 to 2016 at the Regional Referral Center for Hereditary Endocrine Tumors...
May 22, 2017: Endocrine
https://www.readbyqxmd.com/read/28529993/endoscopic-treatment-for-high-risk-t1-colorectal-cancer-is-it-better-to-begin-with-endoscopic-or-surgical-treatment
#12
EDITORIAL
Shintaro Fujihara, Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Akira Yoshitake, Akihiro Deguchi, Tsutomu Masaki
No abstract text is available yet for this article.
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28529878/neuroimaging-in-pre-motor-parkinson-s-disease
#13
REVIEW
Thomas R Barber, Johannes C Klein, Clare E Mackay, Michele T M Hu
The process of neurodegeneration in Parkinson's disease begins long before the onset of clinical motor symptoms, resulting in substantial cell loss by the time a diagnosis can be made. The period between the onset of neurodegeneration and the development of motoric disease would be the ideal time to intervene with disease modifying therapies. This pre-motor phase can last many years, but the lack of a specific clinical phenotype means that objective biomarkers are needed to reliably detect prodromal disease...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28529753/assessment-of-xerostomia-and-its-impact-on-quality-of-life-in-head-and-neck-cancer-patients-undergoing-radiation-therapy
#14
Pinelopi-Theopisti Memtsa, Maria Tolia, Ioannis Tzitzikas, John Bizakis, Kyriaki Pistevou-Gombaki, Martha Charalambidou, Chrysoula Iliopoulou, George Kyrgias
Xerostomia in head and neck (H&N) cancer patients significantly affects their quality of life (QoL). The aim of the present study was to investigate the associations among QoL, xerostomia and quantity of saliva in a sample of H&N cancer patients who had received conventional radiotherapy (RT). A total of 60 H&N adult patients were enrolled in this prospective study. The patients completed the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (QLQ-C30), the Quality of Life Questionnaire Head and Neck Module (QLQ-H&N35) and the Greek version of the XQ questionnaire at 4 timepoints: At the beginning of RT, at the end of RT, 6 months after RT completion and 1 year after RT completion...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28529709/last-rolls-of-the-yoyo-assessing-the-human-canonical-protein-count
#15
REVIEW
Christopher Southan
In 2004, when the protein estimate from the finished human genome was only 24,000, the surprise was compounded as reviewed estimates fell to 19,000 by 2014. However, variability in the total canonical protein counts (i.e. excluding alternative splice forms) of open reading frames (ORFs) in different annotation portals persists. This work assesses these differences and possible causes. A 16-year analysis of Ensembl and UniProtKB/Swiss-Prot shows convergence to a protein number of ~20,000. The former had shown some yo-yoing, but both have now plateaued...
2017: F1000Research
https://www.readbyqxmd.com/read/28529515/changes-in-leaf-anatomical-traits-enhanced-photosynthetic-activity-of-soybean-grown-in-hydroponics-with-plant-growth-promoting-microorganisms
#16
Roberta Paradiso, Carmen Arena, Veronica De Micco, Maria Giordano, Giovanna Aronne, Stefania De Pascale
The use of hydroponic systems for cultivation in controlled climatic conditions and the selection of suitable genotypes for the specific environment help improving crop growth and yield. We hypothesized that plant performance in hydroponics could be further maximized by exploiting the action of plant growth-promoting organisms (PGPMs). However, the effects of PGPMs on plant physiology have been scarcely investigated in hydroponics. Within a series of experiments aimed to identify the best protocol for hydroponic cultivation of soybean [Glycine max (L...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28529453/the-role-of-germ-cell-loss-during-primordial-follicle-assembly-a-review-of-current-advances
#17
REVIEW
Yuan-Chao Sun, Xiao-Feng Sun, Paul W Dyce, Wei Shen, Hong Chen
In most female mammals, early germline development begins with the appearance of primordial germ cells (PGCs), and develops to form mature oocytes following several vital processes. It remains well accepted that significant germ cell apoptosis and oocyte loss takes place around the time of birth. The transition of the ovarian environment from fetal to neonatal, coincides with the loss of germ cells and the timing of follicle formation. All told it is common to lose approximately two thirds of germ cells during this transition period...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/28529451/role-of-epigenetics-in-uveal-melanoma
#18
REVIEW
Yongyun Li, Renbing Jia, Shengfang Ge
Uveal melanoma (UM) is a severe human malignancy with a high mortality rate that demands continued research into new and alternative forms of prevention and treatment. The emerging field of epigenetics is beginning to unfold an era of contemporary approaches to reducing the risk and improving the clinical treatment of UM. Epigenetic changes have a high prevalence rate in cancer, are reversible in nature, and can lead to cancer characteristics even in mutation-free cells. The information contained in this review highlights and expands on the main mechanisms of epigenetic dysregulation in UM tumorigenesis, progression and metastasis, including microRNA expression, hypermethylation of genes and histone modification...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/28529195/rapid-web-based-platform-for-assessment-of-orthopedic-surgery-patient-care-milestones-a-2-year-validation
#19
Kenneth R Gundle, Dayne T Mickelson, Arien Cherones, Jason Black, Doug P Hanel
OBJECTIVE: To determine the validity, feasibility, and responsiveness of a new web-based platform for rapid milestone-based evaluations of orthopedic surgery residents. SETTING: Single academic medical center, including a trauma center and pediatrics tertiary hospital. PARTICIPANTS: Forty residents (PG1-5) in an orthopedic residency program and their faculty evaluators. METHODS: Residents and faculty were trained and supported in the use of a novel trainee-initiated web-based evaluation system...
May 18, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28529188/grade-guidelines-17-assessing-the-risk-of-bias-associated-with-missing-participant-outcome-data-in-a-body-of-evidence
#20
Gordon H Guyatt, Shanil Ebrahim, Pablo Alonso-Coello, Bradley C Johnston, Alexander G Mathioudakis, Matthias Briel, Reem A Mustafa, Xin Sun, Stephen D Walter, Diane Heels-Ansdell, Ignacio Neumann, Lara A Kahale, Alfonso Iorio, Joerg Meerpohl, Holger J Schünemann, Elie A Akl
OBJECTIVE: To provide GRADE guidance for assessing risk of bias across an entire body of evidence consequent on missing data for systematic reviews of both binary and continuous outcomes. STUDY DESIGN: Systematic survey of published methodological research, iterative discussions, testing in systematic reviews, and feedback from the GRADE Working Group. RESULTS: Approaches begin with a primary meta-analysis using a complete case analysis followed by sensitivity meta-analyses imputing, in each study, data for those with missing data, and then pooling across studies...
May 18, 2017: Journal of Clinical Epidemiology
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