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https://www.readbyqxmd.com/read/28730915/burnout-among-danish-prison-personnel-a-question-of-quantitative-and-emotional-demands
#1
Dorte Raaby Andersen, Lars Peter Andersen, Charlotte Ann Gadegaard, Annie Høgh, Annick Prieur, Thomas Lund
Objectives The objective of this follow-up study was to investigate associations between individual, occupational and work environment factors and burnout among both uniformed and non-uniformed personnel working in the Danish Prison and Probation Service. Methods The participants (N = 4808) with client contact received a questionnaire in 2010 and again in 2011. In 2010, 2843 participants responded to the questionnaire (59.1%), and in 2011, 1741 responded to the questionnaire, yielding a response rate of 61...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28721099/sociodemographic-characteristics-of-nonparticipants-in-the-danish-colorectal-cancer-screening-program-a-nationwide-cross-sectional-study
#2
Mette Bach Larsen, Ellen M Mikkelsen, Morten Rasmussen, Lennart Friis-Hansen, Anders U Ovesen, Hans Bjarke Rahr, Berit Andersen
INTRODUCTION: Fecal occult blood tests are recommended for colorectal cancer (CRC) screening in Europe. Recently, the fecal immunochemical test (FIT) has come into use. Sociodemographic differences between participants and nonparticipants may be less pronounced when using FIT as there are no preceding dietary restrictions and only one specimen is required. The aim of this study was to examine the associations between sociodemographic characteristics and nonparticipation for both genders, with special emphasis on those who actively unsubscribe from the program...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28717904/a-description-of-deaths-following-emergency-abdominal-surgery
#3
Henrik Wolsted, Ann Merete Møller, Mai-Britt Tolstrup, Morten Vester-Andersen
OBJECTIVE: Emergency major abdominal surgery carries a high mortality rate. The aim of this present study was to characterize a population of deceased abdominal surgical patients, to examine how many died unexpectedly and how many were subject to treatment limitations. MATERIALS AND METHODS: We included adult emergency abdominal surgical patients who died within 30 days postoperatively. We collected data from January 1, 2013, to December 31, 2014, in a Danish tertiary care hospital (Herlev)...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28716578/simulation-to-aid-in-interpreting-biological-relevance-and-setting-of-population-level-protection-goals-for-risk-assessment-of-pesticides
#4
Christopher John Topping, Robert Luttik
Specific protection goals (SPGs) comprise an explicit expression of the environmental components that need protection and the maximum impacts that can be tolerated. SPGs are set by risk managers and are typically based on protecting populations or functions. However, the measurable endpoints available to risk managers, at least for vertebrates, are typically laboratory tests. We demonstrate, using the example of eggshell thinning in skylarks, how simulation can be used to place laboratory endpoints in context of population-level effects as an aid to setting the SPGs...
July 14, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28715709/parental-age-and-childhood-cancer-risk-a-danish-population-based-registry-study
#5
Zuelma A Contreras, Johnni Hansen, Beate Ritz, Jorn Olsen, Fei Yu, Julia E Heck
BACKGROUND: Though the association between parental age at child's birth and the risk of childhood cancer has been previously investigated, the evidence to date is inconclusive and scarce for rarer cancer types. METHODS: Cancer cases (N=5,856) were selected from all children born from 1968 to 2014 and diagnosed from 1968 to 2015 in Denmark at less than 16 years of age listed in the nationwide Danish Cancer Registry. Cases were individually matched to controls (1:100) on sex and year of birth with a total of 585,594 controls randomly sampled from all live births in Denmark from the Danish Central Population Registry...
July 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28714553/lithium-in-drinking-water-and-the-incidence-of-bipolar-disorder-a-nation-wide-population-based-study
#6
Lars V Kessing, Thomas A Gerds, Nikoline N Knudsen, Lisbeth F Jørgensen, Søren M Kristiansen, Denitza Voutchkova, Vibeke Ernstsen, Jörg Schullehner, Birgitte Hansen, Per K Andersen, Annette K Ersbøll
OBJECTIVE: Animal data suggest that subtherapeutic doses, including micro doses, of lithium may influence mood, and lithium levels in drinking water have been found to correlate with the rate of suicide. It has never been investigated whether consumption of lithium may prevent the development of bipolar disorder (primary prophylaxis). In a nation-wide population-based study, we investigated whether long-term exposure to micro levels of lithium in drinking water correlates with the incidence of bipolar disorder in the general population, hypothesizing an inverse association in which higher long-term lithium exposure is associated with lower incidences of bipolar disorder...
July 17, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28712803/maternal-asthma-severity-and-control-during-pregnancy-and-risk-of-offspring-asthma
#7
Xiaoqin Liu, Esben Agerbo, Vivi Schlünssen, Rosalind J Wright, Jiong Li, Trine Munk-Olsen
BACKGROUND: Severe and uncontrolled asthma during pregnancy has been linked to several unfavorable perinatal outcomes. However, current knowledge on the association between the severity and control of maternal asthma and offspring asthma is sparse. OBJECTIVE: We sought to investigate the extent to which offspring asthma is influenced by maternal asthma severity and control during pregnancy. METHODS: We performed a prospective population-based cohort study...
June 27, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28712434/does-vital-exhaustion-increase-the-risk-of-type-2-diabetes-a-prospective-study
#8
Sasia Volden, Cathrine Lawaetz Wimmelmann, Trine Flensborg-Madsen
BACKGROUND: There is evidence that both stress and depression have a causal relationship with type 2 diabetes suggesting that vital exhaustion (VE) too could be a risk factor. The association between VE and type 2 diabetes has, however, not been investigated prospectively. AIM: To prospectively investigate whether VE is associated with an increased risk of type 2 diabetes in a Danish population. METHODS: A prospective cohort study based on the Copenhagen City Heart Study (1991-1993)...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28712019/maternal-body-mass-index-before-pregnancy-as-a-risk-factor-for-adhd-and-autism-in-children
#9
Christina Hebsgaard Andersen, Per Hove Thomsen, Ellen Aagaard Nohr, Sanne Lemcke
The risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) may be influenced by environmental factors such as maternal obesity before pregnancy. Previous studies investigating those associations have found divergent results. We aim to investigate in a large birth cohort this association further in children with ADHD, ASD and comorbid ADHD and ASD. Our study population consisted of 81,892 mother-child pairs participating in the Danish National Birth Cohort (DNBC). Information about pre-pregnancy weight and height was collected in week 16 of pregnancy; the analysis was divided into groups based on BMI...
July 15, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28709436/satisfaction-discomfort-obligations-and-concerns-in-population-based-breast-cancer-screening-cross-sectional-study-in-a-danish-population
#10
Pernille Gabel, Mette Bach Larsen, Pernille Bjørnholt Nielsen, Dorte Brandt Svendstrup, Berit Andersen
BACKGROUND: Potential barriers to breast cancer screening adherence include patient satisfaction, as well as pain, feeling obliged to participate, and other concerns that might compromise the level of satisfaction. The present study aimed to assess the overall satisfaction of Danish citizens with their breast cancer screening experiences, as well as their level of discomfort, concerns, and feelings of obligation to participate. Furthermore, we analyzed the associations between overall satisfaction and the remaining outcomes...
July 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28708757/increased-incidence-rate-of-trauma-and-stressor-related-disorders-in-denmark-following-the-breivik-attacks-in-norway
#11
Bertel T Hansen, Peter T Dinesen, Søren D Østergaard
BACKGROUND: On July 22, 2011, Anders Breivik killed 77 adults and children in Norway. Having recently documented increases in the incidence of trauma- and stressor-related disorders in Denmark after the 9/11 attacks, we hypothesized that the Breivik attacks-due to their geographical proximity-would be followed by even larger increases in Denmark. METHODS: Using population-based data from the Danish Psychiatric Central Research Register (1995-2012), we conducted an intervention analysis of the change in the incidence of trauma- and stressor-related disorders following the Breivik attacks...
July 13, 2017: Epidemiology
https://www.readbyqxmd.com/read/28707513/cross-cultural-adaptation-and-validation-of-the-danish-10-item-connor-davidson-resilience-scale-among-hospital-staff
#12
Line Skjødt Lauridsen, Morten Vejs Willert, Anita Eskildsen, David Høyrup Christiansen
OBJECTIVES: The 10-item Connor-Davidson Resilience Scale (CD-RISC 10) is a brief instrument measuring resilience in adults. The scale has shown sound psychometric properties in different populations and cultures. Our objectives were to cross-culturally adapt the CD-RISC 10 into Danish and to establish the psychometric properties of the Danish version in terms of internal consistency, construct validity and longitudinal validity. METHODS: The CD-RISC 10 was translated using established guidelines...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28707140/disordered-gambling-prevalence-methodological-innovations-in-a-general-danish-population-survey
#13
Glenn W Harrison, Lasse J Jessen, Morten I Lau, Don Ross
We study Danish adult gambling behavior with an emphasis on discovering patterns relevant to public health forecasting and economic welfare assessment of policy. Methodological innovations include measurement of formative in addition to reflective constructs, estimation of prospective risk for developing gambling disorder rather than risk of being falsely negatively diagnosed, analysis with attention to sample weights and correction for sample selection bias, estimation of the impact of trigger questions on prevalence estimates and sample characteristics, and distinguishing between total and marginal effects of risk-indicating factors...
July 13, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/28705951/excess-mortality-among-patients-with-multiple-sclerosis-in-denmark-has-dropped-significantly-over-the-past-six-decades-a-population-based-study
#14
Nils Koch-Henriksen, Bjarne Laursen, Egon Stenager, Melinda Magyari
BACKGROUND: Lifetime expectancy in multiple sclerosis (MS) is reduced. Few studies have had sufficient follow-up or sufficient number of patients to assess if survival has improved with time. However, a recent meta-analysis found no time-dependent change in MS excess mortality across studies over recent decades. OBJECTIVE: To investigate whether short-term all-cause excess mortality in patients with MS in the total Danish population has changed over the last six decades...
August 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28704231/male-fertility-after-inguinal-hernia-mesh-repair-a-national-register-study
#15
Andreas Pagh Kohl, Kristoffer Andresen, Jacob Rosenberg
OBJECTIVE: To determine whether patients who receive an inguinal hernia repair father the same number of children as the background population. BACKGROUND: Although the effect of inguinal hernia repair on male fertility has previously been investigated through indirect measures, no previous studies have evaluated the final measure of male fertility, which is the number of children fathered by patients. METHODS: Prospectively collected data on 32,621 male patients between the ages of 18 and 55 years who received 1 or more inguinal hernia repairs during the years 1998 to 2012 were found in 5 comprehensive Danish linked registers...
July 12, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28699369/single-centre-experience-with-intradetrusor-injection-of-onabotulinumtoxina-a-retrospective-study-of-the-years-2003-2012-in-a-danish-population
#16
Frederikke Eichner Christiansen, Torben Brøchner Pedersen, Jacob Juel, Hans Jørgen Kirkeby
OBJECTIVE: This study aimed to evaluate the efficacy of treatment for incontinence due to neurogenic detrusor overactivity (NDO) and idiopathic detrusor overactivity (IDO) with onabotulinumtoxinA (BoNT-A) at Aarhus University Hospital, Skejby, Denmark. MATERIALS AND METHODS: The data were collected retrospectively by systematic review of the patient records from March 2003 to May 2012. Patients treated with BoNT-A over the age of 18 years were included. Treatment indication, diagnosis, adverse events, treatment interval, duration of effect and effect grade were registered...
July 12, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28699189/human-papillomavirus-infects-placental-trophoblast-and-hofbauer-cells-but-appears-not-to-play-a-causal-role-in-miscarriage-and-preterm-labor
#17
Lea Maria Margareta Ambühl, Anne Katrine Leonhard, Carina Widen Zakhary, Annemette Jørgensen, Jan Blaakaer, Karen Dybkaer, Ulrik Baandrup, Niels Uldbjerg, Suzette Sørensen
INTRODUCTION: Recently, an association between human papillomavirus (HPV) infection and both spontaneous abortion and spontaneous preterm delivery was suggested. However, the reported HPV prevalence in pregnant women varies considerably and reliable conclusions are difficult. We aimed to investigate HPV infection in placental tissue of a Danish study cohort. Furthermore, we studied the cellular localization of HPV. MATERIAL AND METHODS: In this prospective case-control study, placental tissue was analyzed for HPV infection by nested PCR in the following four study groups: full-term delivery (n=103), spontaneous preterm delivery (n=69), elective abortion (n=54), and spontaneous abortion (n=44)...
July 12, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28697450/changes-in-genetically-drifted-h3n2-influenza-a-viruses-and-vaccine-effectiveness-in-adults-65-years-and-older-during-the-2016-17-season-in-denmark
#18
Ramona Trebbien, Thea K Fischer, Tyra G Krause, Lene Nielsen, Xiaohui Chen Nielsen, Lenette Sandborg Weinreich, Joanna Lis-Tønder, Marianne Nielsine Skov, Claus Bohn Christiansen, Hanne-Dorthe Emborg
BACKGROUND: In Denmark, influenza A virus of the subtype H3N2 has been dominating the 2016/17 season, as in most countries of the Northern Hemisphere. OBJECTIVES: This study was conducted as part of the Danish seasonal influenza surveillance programme to genetically characterize circulating H3N2 viruses and determine the seasonal vaccine effectiveness (VE) overall in the Danish population and further on the virus cluster level. STUDY DESIGN: Influenza virus positive samples submitted for the national surveillance programme were genetically characterized by sequencing...
June 29, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28688779/formulation-stabilisation-and-encapsulation-of-bacteriophage-for-phage-therapy
#19
REVIEW
Danish J Malik, Ilya J Sokolov, Gurinder K Vinner, Francesco Mancuso, Salvatore Cinquerrui, Goran T Vladisavljevic, Martha R J Clokie, Natalie J Garton, Andrew G F Stapley, Anna Kirpichnikova
Against a backdrop of global antibiotic resistance and increasing awareness of the importance of the human microbiota, there has been resurgent interest in the potential use of bacteriophages for therapeutic purposes, known as phage therapy. A number of phage therapy phase I and II clinical trials have concluded, and shown phages don't present significant adverse safety concerns. These clinical trials used simple phage suspensions without any formulation and phage stability was of secondary concern. Phages have a limited stability in solution, and undergo a significant drop in phage titre during processing and storage which is unacceptable if phages are to become regulated pharmaceuticals, where stable dosage and well defined pharmacokinetics and pharmacodynamics are de rigueur...
May 14, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28679695/mice-as-stowaways-colonization-history-of-danish-striped-field-mice
#20
Liselotte Wesley Andersen, Magnus Jacobsen, Christina Vedel-Smith, Thomas Secher Jensen
Species from the steppe region of Eastern Europe likely colonized northwestern Europe in connection with agriculture after 6500 BP. The striped field mouse (Apodemus agrarius Pallas, 1783), is a steppe-derived species often found in human crops. It is common on the southern Danish islands of Lolland and Falster, which have been isolated from mainland Europe since approximately 10 300-8000 BP. Thus, this species could have been brought in with humans in connection with agriculture, or it could be an earlier natural invader...
July 2017: Biology Letters
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