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https://www.readbyqxmd.com/read/28329459/nineteen-years-of-adult-congenital-heart-surgery-in-a-single-center
#1
Madurra Perinpanayagam, Signe H Larsen, Kristian Emmertsen, Marianne B Møller, Vibeke E Hjortdal
BACKGROUND: Adults with congenital heart disease are a growing population. We describe surgical interventions, short- and long-term mortality and morbidity, and risk factors for adverse events in a population-based cohort. METHODS: Patients over or equal to 18 years with congenital heart disease who underwent cardiac surgery at Aarhus University Hospital, Denmark, from 1994 to 2012 were included in the study. Diagnoses, surgical procedures, postoperative complications, and survival were identified in hospital databases, medical records, and the Danish Civil Registration System...
March 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28324016/cardiorespiratory-fitness-and-adiposity-as-determinants-of-metabolic-health-pooled-analysis-of-two-twin-cohorts
#2
Sakari Jukarainen, René Holst, Christine Dalgård, Päivi Piirilä, Jesper Lundbom, Antti Hakkarainen, Nina Lundbom, Aila Rissanen, Jaakko Kaprio, Kirsten Ohm Kyvik, Thorkild I A Sørensen, Kirsi H Pietiläinen
Context: The joint effects of cardiorespiratory fitness and body composition on metabolic health are not well known. Objective: To examine the associations of cardiorespiratory fitness (CRF), fat free mass index (FFMI) and fat mass index (FMI) with metabolic health in individual twins and controlling for genetic and shared environmental effects by studying monozygotic intrapair differences. Design, setting & participants: Two cross-sectional samples of healthy adult monozygotic and dizygotic twins were drawn from population-based Danish and Finnish national twin registries (n=996 and n=309)...
January 23, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323923/genetic-variation-of-follicle-stimulating-hormone-action-is-associated-with-age-at-testicular-growth-in-boys
#3
Alexander S Busch, Casper P Hagen, Katharina M Main, Anita Pereira, Camila Corvalan, Kristian Almstrup, Veronica Mericq, Anders Juul
Context: Although genetic factors play a pivotal role in male pubertal timing, genome-wide association studies have identified only a small number of loci. Genetic variation of FSH action affects adult reproductive parameters and female pubertal timing. Objective: To investigate whether genetic variation affecting FSH action is associated with onset of puberty in boys. Design: Cross-sectional and longitudinal study of two cohorts of healthy boys...
February 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28322364/marginal-bone-loss-after-ten-years-in-an-adult-danish-population-a-radiographic-study
#4
Golnosh Bahrami, Michael Vaeth, Ann Wenzel, Flemming Isidor
PURPOSE: To evaluate marginal bone loss over a 10-year period in individuals and in tooth groups in relation to age and level of marginal bone. MATERIALS AND METHODS: In 1997, 616 randomly selected individuals (mean age: 42 years, range: 21-63 years) underwent a full-mouth radiographic survey. In 2008, the survey was repeated in 362 of the same individuals (182 women and 180 men). The marginal bone level of each tooth was measured in mm from the cementoenamel junction to the marginal bone...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28319247/occupational-and-recreational-physical-activity-and-parkinson-s-disease-in-denmark
#5
I-Fan Shih, Charlotte Starhof, Christina Funch Lassen, Johnni Hansen, Zeyan Liew, Beate Ritz
Objectives This study aimed to examine whether occupational and physical activity (PA) at different ages contribute to Parkinson's disease (PD) risk in a large population-based case-control study in Denmark. Methods We identified 1828 PD patients from the Danish National Hospital Register and recruited 1909 gender and year of birth matched controls from the Danish Central Population Register. Occupational and leisure-time PA were determined from a job exposure matrix based on occupational history and self-reported leisure-time information...
March 20, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28317459/outcome-of-peripheral-t-cell-lymphoma-in-first-complete-remission-a-danish-swedish-population-based-study
#6
Henrik Cederleuf, Lasse Hjort Jakobsen, Fredrik Ellin, Peter de Nully Brown, Thomas Stauffer Larsen, Martin Bøgsted, Thomas Relander, Mats Jerkeman, Tarec Christoffer El-Galaly
In the present study, we investigate the outcome of 109 Danish and 123 Swedish patients with nodal PTCL in first complete remission (CR), and examine the impact of imaging-based follow-up (FU) strategies. The patients were selected by the following criteria: (a) newly diagnosed nodal PTCL from 2007 to 2012, (b) age ≥18 years, and (c) CR after CHOP or CHOEP therapy. FU guidelines in Sweden included symptom assessment, clinical examinations and blood tests at 3-4-month intervals for 2 years. FU strategies in Denmark was similar but included routine imaging, usually every 6 months for 2 years...
March 20, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28317318/men-with-biopsy-confirmed-hepatocellular-adenoma-have-a-high-risk-of-progression-to-hcc-a-nationwide-population-based-study
#7
Lars Bossen, Henning Grønbaek, Peter Lykke Eriksen, Peter Jepsen
BACKGROUND: Hepatocellular adenoma is a benign liver tumour that may transform to hepatocellular carcinoma (HCC). We used data from Danish nationwide healthcare registries to investigate the incidence and prognosis of hepatocellular adenoma. METHODS: We included all patients with a hospital discharge diagnosis for benign liver tumour (ICD-10: D13.4) in 1997-2012 and a liver biopsy confirming the hepatocellular adenoma diagnosis. Follow-up began one year after adenoma diagnosis, to minimize the possibility that the tumour was a misdiagnosed HCC...
March 19, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28301514/apolipoprotein-d-expression-does-not-predict-breast-cancer-recurrence-among-tamoxifen-treated-patients
#8
Daniella Klebaner, Stephen Hamilton-Dutoit, Thomas Ahern, Anatasha Crawford, Thomas Jakobsen, Deirdre P Cronin-Fenton, Per Damkier, Emiel Janssen, Anders Kjaersgaard, Anne Gulbech Ording, Håvard Søiland, Henrik Toft Sørensen, Timothy L Lash, Ylva Hellberg
BACKGROUND: Apolipoprotein D (ApoD) has been proposed as a predictor of breast cancer recurrence among estrogen receptor-positive (ER+), tamoxifen-treated patients. METHODS: We conducted a population-based case-control study nested in a population of 11,251 women aged 35-69 years at diagnosis with Stage I-III breast cancer between 1985 and 2001 on Denmark's Jutland Peninsula and registered with the Danish Breast Cancer Cooperative Group. We identified 541 recurrent or contralateral breast cancers cases among women with ER+ disease treated with tamoxifen for at least 1 year and 300 cases in women with ER- disease never treated with tamoxifen...
2017: PloS One
https://www.readbyqxmd.com/read/28301245/prevalence-of-taxa-of-pasteurellaceae-among-populations-of-healthy-captive-psittacine-birds
#9
M Bisgaard, Di Xin, M F Bertelsen, A M Bojesen, H Christensen
Sixty-two strains of Pasteurellaceae-like bacteria were isolated from the tracheas of 87 clinically healthy psittacine birds in two Danish zoos. The isolates were identified by a combination of rpoB and 16S rRNA gene sequencing and by matrix-assisted laser desorption-ionization time of flight. Twenty-eight strains belonged to the genus Volucribacter or were related to this genus and to the unnamed taxon 34 of Bisgaard, and 28 strains were related to the unnamed taxon 44 of Bisgaard. Four strains were identified as Pasteurella multocida , two isolates were classified with the related taxon 45 of Bisgaard, and a single isolate was classified as Pasteurella sp...
March 2017: Avian Diseases
https://www.readbyqxmd.com/read/28296516/eye-disorders-among-adult-people-diagnosed-with-infantile-autism-in-childhood-a-longitudinal-case-control-study
#10
Svend Erik Mouridsen, Bente Rich, Torben Isager
PURPOSE: The objective of this study was to compare the prevalence and types of eye disorders in a clinical sample of 118 adult people diagnosed with infantile autism (IA) during childhood with 336 sex- and age-matched controls from the general population. METHODS: All participants were screened through the nationwide Danish National Hospital Register. The average observation time of both groups was 37.2 years, and mean age was 49.6 years, by the end of the observation period...
March 15, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28290942/increased-postdeployment-use-of-medication-for-common-mental-disorders-in-danish-gulf-war-veterans
#11
Lars Ravnborg Nissen, Christian Stoltenberg, Mia Sadowa Vedtofte, Anni Brit Sternhagen Nielsen, Jacob Louis Marott, Finn Gyntelberg, Bernadette Guldager
BACKGROUND: Gulf War veterans (GWVs) have an elevated risk of reporting symptoms of mental disorders as compared with nondeployed military controls. A difficulty in the Gulf War health research is that most health outcomes are self-reported; therefore, it is highly relevant to study objective outcomes in this line of research. The Danish National Prescription Registry provides an opportunity to use the prescription of drugs as an objective evaluation of the impact of mental health disorders at the individual level...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290468/ageing-with-neurogenic-bowel-dysfunction
#12
S D Nielsen, P M Faaborg, N B Finnerup, P Christensen, K Krogh
STUDY DESIGN: Longitudinal study with postal survey. OBJECTIVES: To describe changes in the patterns of neurogenic bowel dysfunction and bowel management in a population of people with spinal cord injury (SCI) followed for two decades. SETTING: Members of the Danish SCI Association. METHODS: In 1996, a validated questionnaire on bowel function was sent to the members of the Danish SCI Association (n=589). The same questionnaire was sent to all the surviving members in 2006 (n=284) and in 2015 (n=178)...
March 14, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28288406/early-adversity-and-risk-for-moderate-to-severe-unipolar-depressive-disorder-in-adolescence-and-adulthood-a-register-based-study-of-978-647-individuals
#13
Signe Kirk Dahl, Janne Tidselbak Larsen, Liselotte Petersen, Mads Bonde Ubbesen, Preben Bo Mortensen, Trine Munk-Olsen, Katherine Louise Musliner
BACKGROUND: Early adversity is a known risk factor for unipolar depression. We examined the impact of 9 types of early adversity on risk for moderate to severe unipolar depression in adolescence or adulthood, and evaluated whether these effects were moderated by gender and adversity timing. METHODS: We conducted a prospective, population-based cohort study using Danish national registers. The sample included all individuals born in Denmark between 1980 and 1998 (N=978,647)...
March 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28280390/a-nationwide-population-based-cross-sectional-survey-of-health-related-quality-of-life-in-patients-with-myeloproliferative-neoplasms-in-denmark-mpnhealthsurvey-survey-design-and-characteristics-of-respondents-and-nonrespondents
#14
Nana Brochmann, Esben Meulengracht Flachs, Anne Illemann Christensen, Christen Lykkegaard Andersen, Knud Juel, Hans Carl Hasselbalch, Ann-Dorthe Zwisler
OBJECTIVE: The Department of Hematology, Zealand University Hospital, Denmark, and the National Institute of Public Health, University of Southern Denmark, created the first nationwide, population-based, and the most comprehensive cross-sectional health-related quality of life (HRQoL) survey of patients with myeloproliferative neoplasms (MPNs). In Denmark, all MPN patients are treated in public hospitals and treatments received are free of charge for these patients. Therefore, MPN patients receive the best available treatment to the extent of its suitability for them and if they wish to receive the treatment...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28277046/social-disparities-in-diabetes-care-a-general-population-study-in-denmark
#15
Andreas Heltberg, John Sahl Andersen, Jakob Kragstrup, Volkert Siersma, Håkon Sandholdt, Christina Ellervik
OBJECTIVE: We investigated the association between socioeconomic factors and the attainment of treatment goals and pharmacotherapy in patients with type 2 diabetes in Denmark. DESIGN: A cross-sectional population study. SETTING: The municipality of Naestved, Denmark. SUBJECTS: We studied 907 patients with type 2 diabetes identified from a random sample of 21,205 Danish citizens. MAIN OUTCOME MEASURES: The proportion of patients who were not achieving goals for diabetes care based on their HbA1c, LDL-cholesterol, blood pressure, and lifestyle, and the proportion of patients who were treated with antihypertensive and cholesterol- and glucose-lowering medication...
March 2017: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/28275316/cohort-description-the-danish-study-of-functional-disorders
#16
Thomas Meinertz Dantoft, Jeanette Frost Ebstrup, Allan Linneberg, Sine Skovbjerg, Anja Lykke Madsen, Jesper Mehlsen, Louise Brinth, Lene Falgaard Eplov, Tina Wisbech Carstensen, Andreas Schroder, Per Klausen Fink, Erik Lykke Mortensen, Torben Hansen, Oluf Pedersen, Torben Jørgensen
The Danish study of Functional Disorders (DanFunD) cohort was initiated to outline the epidemiology of functional somatic syndromes (FSS) and is the first larger coordinated epidemiological study focusing exclusively on FSS. FSS are prevalent in all medical settings and can be defined as syndromes that, after appropriate medical assessment, cannot be explained in terms of a conventional medical or surgical disease. FSS are frequent and the clinical importance varies from vague symptoms to extreme disability...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28271296/cross-cultural-translation-adaptation-and-reliability-of-the-danish-m-d-andeson-dysphagia-inventory-mdadi-in-patients-with-head-and-neck-cancer
#17
Sara Fredslund Hajdú, Christina Caroline Plaschke, Christoffer Johansen, Susanne Oksbjerg Dalton, Irene Wessel
The objectives were to translate and culturally adapt the M.D. Anderson Dysphagia Inventory (MDADI) into Danish and subsequently test the reliability of the Danish version. The MDADI was translated into Danish and cross culturally adapted through cognitive interviews. The final version was test-retest evaluated in a group of head and neck cancer (HNC) patients who responded to the questionnaire twice with a mean of eight days apart. Interclass correlation coefficient, Cronbach's alpha, floor and ceiling effects, standard error of measurement and minimal detectable change were investigated...
March 7, 2017: Dysphagia
https://www.readbyqxmd.com/read/28271023/determinants-of-preferences-for-lifestyle-changes-versus-medication-and-beliefs-in-ability-to-maintain-lifestyle-changes-a-population-based-survey
#18
Dorte Ejg Jarbøl, Pia Veldt Larsen, Dorte Gyrd-Hansen, Jens Søndergaard, Carl Brandt, Anja Leppin, Benedicte Lind Barfoed, Jesper Bo Nielsen
Preferences for medication treatment versus lifestyle changes are of major importance in the management of chronic diseases. This study aims to investigate determinants of preference for lifestyle changes versus medication for prevention of cardiovascular disease as well as determinants of respondents' beliefs in their ability to maintain lifestyle changes. A representative sample of 40-60-year old Danish inhabitants was in 2012 invited to a survey and were asked to imagine that they had been diagnosed as being at increased risk of heart disease...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28267247/validity-of-physical-activity-and-cardiorespiratory-fitness-in-the-danish-cohort-diet-cancer-and-health-next-generations
#19
Lene Lerche, Anja Olsen, Kristina Elin Nielsen Petersen, Agnetha Linn Rostgaard-Hansen, Lars Ove Dragsted, Nikolai Baastrup Nordsborg, Anne Tjønneland, Jytte Halkjaer
Valid assessments of physical activity (PA) and cardiorespiratory fitness (CRF) is essential in epidemiological studies to define dose-response relationship for e.g. formulating thorough recommendations of an appropriate pattern of PA to maintain good health. The aim of this study was to validate the Danish step test, the physical activity questionnaire Active-Q and self-rated fitness against directly measured maximal oxygen uptake (VO2 max). A population based subsample (n=125) was included from the 'Diet, Cancer and Health - Next Generations' (DCH-NG) cohort which is under establishment...
March 7, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28265802/translation-and-adaptation-of-the-genetic-counselling-outcome-scale-gcos-24-for-use-in-denmark
#20
Birgitte Rode Diness, Gritt Overbeck, Tina Duelund Hjortshøj, Trine Bjørg Hammer, Susanne Timshel, Else Sørensen, Marion McAllister
Outcome measurement in clinical genetics is challenging. Robust outcome measures are needed to provide evidence to support service development within genetic counseling. The Genetic Counselling Outcome Scale (GCOS-24), a Patient Reported Outcome Measure (PROM), was developed in English and validated with clinical genetics patients in the British NHS. This study reports the translation and adaptation of the GCOS-24 for use in Denmark. GCOS-24 was translated and back translated, supervised by an expert committee...
March 6, 2017: Journal of Genetic Counseling
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