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https://www.readbyqxmd.com/read/28213927/long-term-hospitalisation-rates-among-5-year-survivors-of-hodgkin-lymphoma-in-adolescence-or-young-adulthood-a-nationwide-cohort-study
#1
Kathrine Rugbjerg, Maja Maraldo, Marianne C Aznar, David J Cutter, Sarah C Darby, Lena Specht, Jørgen H Olsen
In the present study, we report on the full range of physical diseases acquired by survivors of Hodgkin lymphoma diagnosed in adolescence or young adulthood. In a Danish nationwide population-based cohort study, 1768 five-year survivors of Hodgkin lymphoma diagnosed at ages 15-39 years during 1943-2004 and 228,447 comparison subjects matched to survivors on age and year of birth were included. Hospital discharge diagnoses and bed-days during 1977-2010 were obtained from the Danish Patient Register for 145 specific disease categories gathered in 14 main diagnostic groups...
February 18, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28213896/filaggrin-loss-of-function-mutations-atopic-dermatitis-and-risk-of-actinic-keratosis-results-from-two-cross-sectional-studies
#2
Y M F Andersen, A Egeberg, E Balslev, C L T Jørgensen, P B Szecsi, S Stender, J Kaae, A Linneberg, G Gislason, L Skov, P M Elias, J P Thyssen
BACKGROUND: Common loss-of-function mutations in filaggrin gene (FLG) represent a strong genetic risk factor for atopic dermatitis (AD). Homozygous mutation carriers typically display ichthyosis vulgaris (IV) and many have concomitant AD. Previously, homozygous, but not heterozygous, filaggrin gene mutations have been associated with squamous cell carcinomas. OBJECTIVE: The first objective was to examine the association between FLG mutations and actinic keratosis (AK)...
February 18, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28213711/implantable-cardioverter-defibrillators-for-primary-prevention-in-dilated-cardiomyopathy-post-danish-an-updated-meta-analysis-and-systematic-review-of-randomized-controlled-trials
#3
Georg Wolff, Yingfeng Lin, Athanasios Karathanos, Maximilian Brockmeyer, Susanne Wolters, Bernd Nowak, Alexander Fürnkranz, Hisaki Makimoto, Malte Kelm, Volker Schulze
BACKGROUND: Sudden cardiac death (SCD) is frequent in patients with heart failure due to dilated cardiomyopathy (DCM). Implantable cardioverter/defibrillator (ICD) device therapy is currently used for primary prevention. However, publication of the DANISH trial has recently given reason for doubt, showing no significant improvement in all-cause mortality in comparison to contemporary medical therapy. METHODS: We performed a meta-analysis of all randomized controlled trials comparing ICD therapy to medical therapy (MT) for primary prevention in DCM...
February 17, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28211588/is-this-back-pain-killing-me-all-cause-and-cardiovascular-specific-mortality-in-older-danish-twins-with-spinal-pain
#4
M Fernandez, E Boyle, J Hartvigsen, M L Ferreira, K M Refshauge, C G Maher, K Christensen, J L Hopper, P H Ferreira
BACKGROUND: Few studies have examined the potentially reduced life expectancy associated with spinal pain (i.e. low back and neck pain) in an ageing population, particularly after controlling for familial factors, including genetics. METHODS: We investigated whether spinal pain increased the rate of all-cause and disease-specific cardiovascular mortality in older Danish twins aged ≥70 years. Data from 4391 participants collected at baseline were linked with the Danish Cause of Death Registry with the study ending on 31 December 2014...
February 17, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28210793/a-national-population-based-cohort-study-of-urethral-injection-therapy-for-female-stress-and-mixed-urinary-incontinence-the-danish-urogynaecological-database-2007-2011
#5
Margrethe Foss Hansen, Gunnar Lose, Ulrik Schiøler Kesmodel, Kim Oren Gradel
INTRODUCTION AND HYPOTHESIS: Urethral injection therapy (UIT) has been performed since the early 20th century and a variety of agents have been launched. In 2006, polyacrylamide hydrogel (PAGH) was introduced and is now widely used as an agent. The objective was to evaluate the efficacy of PAGH based on a national population over a 5-year period (2007-2011) and the influence of patient-related factors, surgeon experience, and department volume. METHODS: A retrospective cohort study was carried out based on data from the Danish Urogynaecological Database (DugaBase)...
February 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28206872/associations-between-education-and-physical-functioning-and-pain-in-adult-danish-cancer-survivors
#6
Dorte Winther, Tina K Nygaard, Trine A Horsbøl, Trille Kjær, Peter Vedsted, Christoffer Johansen, Hanna B Hovaldt, Mette Sandager, Susanne O Dalton
BACKGROUND: Late effects after cancer diagnosis and treatment are common, but only few studies have examined the role of social factors in developing these late effects. The aim of this study was to examine the association between educational level and physical function and pain among cancer survivors two years after diagnosis. MATERIAL AND METHODS: The study population consisted of adult Danish patients with a first-time cancer diagnosis who were sent a questionnaire in 2010 and followed up in 2012...
February 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28202701/chronobiology-differs-between-men-and-women-with-cluster-headache-clinical-phenotype-does-not
#7
Nunu Lund, Mads Barloese, Anja Petersen, Bryan Haddock, Rigmor Jensen
OBJECTIVE: To describe differences between the sexes in the phenotype of cluster headache (CH) in a large, well-characterized clinical CH population. METHODS: Patients from the Danish CH survey aged 18-65 years, diagnosed with CH according to International Classification of Headache Disorders, second edition, completed questionnaires and structured interviews. RESULTS: A total of 351 patients with CH participated, with a male:female ratio of 2:1...
February 15, 2017: Neurology
https://www.readbyqxmd.com/read/28199392/comparison-of-the-population-excess-fraction-of-chlamydia-trachomatis-infection-on-pelvic-inflammatory-disease-at-12-months-in-the-presence-and-absence-of-chlamydia-testing-and-treatment-systematic-review-and-retrospective-cohort-analysis
#8
Bethan Davies, Katy M E Turner, Stella Leung, B Nancy Yu, Maria Frølund, Thomas Benfield, James Blanchard, Henrik Westh, Helen Ward
BACKGROUND: The impact of Chlamydia trachomatis (chlamydia) control on the incidence of pelvic inflammatory disease (PID) is theoretically limited by the proportion of PID caused by chlamydia. We estimate the population excess fraction (PEF) of treated chlamydia infection on PID at 12-months in settings with widespread chlamydia control (testing and treatment) and compare this to the estimated PEF of untreated chlamydia. METHODS: We used two large retrospective population-based cohorts of women of reproductive age from settings with widespread chlamydia control to calculate the PEF of treated chlamydia on PID at 12-months...
2017: PloS One
https://www.readbyqxmd.com/read/28192643/associations-between-substance-use-disorders-and-suicide-or-suicide-attempts-in-people-with-mental-illness-a-danish-nationwide-prospective-register-based-study-of-patients-diagnosed-with-schizophrenia-bipolar-disorder-unipolar-depression-or-personality-disorder
#9
Marie L D Østergaard, Merete Nordentoft, Carsten Hjorthøj
AIM: To estimate and test associations between substance use disorders (SUDs) and both completed suicides and suicide attempts in a population with severe mental illness. DESIGN: Register-based cohort study with adjusted Cox regression of substance use disorders as time-varying covariates. SETTING: Denmark. PARTICIPANTS: People born in Denmark since 1955 with a diagnosis of schizophrenia (n = 35,625), bipolar disorder (n = 9,279), depression (n = 72,530), or personality disorder (n = 63,958)...
February 13, 2017: Addiction
https://www.readbyqxmd.com/read/28188494/palivizumab-exposure-and-the-risk-of-atopic-dermatitis-asthma-and-allergic-rhinoconjunctivitis-a-cross-national-population-based-cohort-study
#10
Ann Haerskjold, Lonny Stokholm, Marie Linder, Simon Francis Thomsen, Gunnar Bergman, Ingegärd Anveden Berglind, Helle Kieler, Henrik Ravn, Lone Graff Stensballe
BACKGROUND: Palivizumab is a humanized monoclonal antibody designed to provide passive immunity against respiratory syncytial virus. It is prescribed to children at high risk for severe infection with respiratory syncytial virus. However, little is known about the risk of the immune-mediated diseases atopic dermatitis, asthma, and allergic rhinoconjunctivitis after palivizumab exposure. AIM: Our objective was to investigate whether exposure to palivizumab was associated with atopic dermatitis, asthma, or allergic rhinoconjunctivitis in childhood...
February 10, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28183396/denheart-differences-in-physical-and-mental-health-across-cardiac-diagnoses-at-hospital-discharge
#11
Selina Kikkenborg Berg, Trine Bernholdt Rasmussen, Lars Thrysoee, Astrid Lauberg, Britt Borregaard, Anne Vinggaard Christensen, Ola Ekholm, Knud Juel, Jette Rolf Svanholm
OBJECTIVE: To describe: (i) differences in patient reported physical and mental health outcomes at hospital discharge between a) cardiac diagnostic groups and b) cardiac patients and a national representative reference population and to describe (ii) in-hospital predicting factors for patient reported outcomes. METHODS: A national cross-sectional survey combined with national register data. From April 2013 to April 2014 all patients (n=34,564) discharged or transferred from one of five Danish Heart Centres were invited to participate...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28182643/ige-sensitization-to-inhalant-allergens-and-the-risk-of-airway-infection-and-disease-a-population-based-study
#12
Tea Skaaby, Lise Lotte Nystrup Husemoen, Betina Heinsbæk Thuesen, Runa Vavia Fenger, Allan Linneberg
BACKGROUND: Immunoglobulin E (IgE) sensitization, which is the propensity to develop IgE antibodies against common environmental allergens, is associated with a lymphocyte T-helper type 2 (Th2) skewed immune response and a high risk of allergic respiratory disease. Little is known about whether IgE sensitization confers an increased risk of respiratory infections in adults. We investigated the association between IgE sensitization and the incidence of acute airway infections, other infections and chronic lower airway disease events as recorded in nation-wide registries...
2017: PloS One
https://www.readbyqxmd.com/read/28182624/socio-demographic-characteristics-of-danish-blood-donors
#13
Kristoffer Sølvsten Burgdorf, Jacob Simonsen, Anna Sundby, Klaus Rostgaard, Ole Birger Pedersen, Erik Sørensen, Kaspar René Nielsen, Mie Topholm Bruun, Morten Frisch, Gustaf Edgren, Christian Erikstrup, Henrik Hjalgrim, Henrik Ullum
BACKGROUND: Blood transfusion is an essential component of a modern healthcare system. Because knowledge about blood donor demography may inform the design of strategies for donor recruitment and retention, we used nationwide registers to characterize the entire population of blood donors in Denmark in 2010. METHODS: The study population comprised all Danes in the age range eligible for blood donation (N = 3,236,753) at the end of 2010. From the Scandinavian Donations and Transfusions (SCANDAT) register, we identified 174,523 persons who donated blood in Danish blood banks at least once in 2010...
2017: PloS One
https://www.readbyqxmd.com/read/28179451/cushing-s-syndrome-in-children-and-adolescents-a-danish-nationwide-population-based-cohort-study
#14
Johanne Marie Holst, Erzsébet Horváth-Puhó, Rb Jensen, Mariane Rix, Niels Thomas Hertel, Olaf Dekkers, Henrik Toft Sørensen, Anders Juul, Jens Otto L Jorgensen
OBJECTIVE: Cushing's syndrome (CS) affects all age groups, but epidemiologic data in young pa-tients are very limited. We therefore examined the incidence, prevalence, and hospital morbidity of CS in children and adolescents. DESIGN: In a nationwide cohort study we included all Danish citizens aged 0-20 years from 1977 to 2012. Data were obtained from the Danish National Patient Registry using the International Classi-fication of Diseases (ICD) codes and the Danish Civil Registration System...
February 8, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28178023/risk-factors-for-acute-care-hospital-readmission-in-older-persons-in-western-countries-a-systematic-review
#15
Mona Kyndi Pedersen, Gabriele Meyer, Lisbeth Uhrenfeldt
BACKGROUND: Hospital readmission in older persons is common and reported as a post-discharge adverse outcome from hospitalization. Readmission relates to a mix of factors associated with increasing age, living conditions, progression of disease as well as factors related to the processes of care. To allow health professionals to focus more intensively on patients at risk of readmission, there is a need to identify the characteristics of those patients. OBJECTIVES: To identify and synthesize the best available evidence on risk factors for acute care hospital readmission within one month of discharge in older persons in Western countries...
February 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28177461/common-breast-cancer-risk-alleles-and-risk-assessment-a-study-on-35%C3%A2-441-individuals-from-the-danish-general-population
#16
C Näslund-Koch, B G Nordestgaard, S E Bojesen
No abstract text is available yet for this article.
January 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28176979/risk-of-pneumonia-and-urinary-tract-infection-within-the-first-week-after-total-hip-arthroplasty-and-the-impact-on-survival
#17
Eva N Glassou, Torben B Hansen, Alma B Pedersen
BACKGROUND: Pneumonia and urinary tract infections (UTIs) increase morbidity and mortality. There is little epidemiological evidence from large population-based studies on risk factors for these infections and subsequent mortality in total hip arthroplasty (THA) patients. AIM: To examine the risk factors of postoperative pneumonia and UTI after THA and their impact on survival. PATIENTS AND METHODS: We used the Danish Hip Arthroplasty Register to identify THAs due to osteoarthritis registered from 2000 to 2013...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28176348/inflammatory-bowel-diseases-in-faroese-born-danish-residents-and-their-offspring-further-evidence-of-the-dominant-role-of-environmental-factors-in-ibd-development
#18
T Hammer, S N Lophaven, K R Nielsen, M von Euler-Chelpin, P Weihe, P Munkholm, J Burisch, E Lynge
BACKGROUND: The incidence of inflammatory bowel disease (IBD) is record high in the Faroe Islands, and many Faroese emigrate to Denmark, where the IBD incidence is considerably lower. AIM: To study the IBD incidence in first-, second- and third-generation immigrants from the Faroe Islands to Denmark to assess the extent to which the immigrants adopt the lower IBD incidence of their new home country. METHODS: Data on Faroese-born Danish residents and their children were retrieved from the Danish Central Population Register for 1980-2014...
February 8, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28174933/dop003-proximal-disease-extension-in-patients-with-limited-ulcerative-colitis-a-danish-population-based-inception-cohort
#19
J Burisch, I Vind, M Prosberg, J-F Colombel, R Ungaro, F Bendtsen, M Vester-Andersen
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172743/p703-risk-of-disease-progression-in-patients-with-crohn-s-disease-after-7-years-of-follow-up-in-a-danish-population-based-inception-cohort
#20
J Burisch, I Vind, M Prosberg, M Dubinsky, C A Siegel, F Bendtsen, M Vester-Andersen
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
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