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Anterior ciliary arteries

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https://www.readbyqxmd.com/read/27922054/first-insight-into-the-proteome-landscape-of-the-porcine-short-posterior-ciliary-arteries-key-signalling-pathways-maintaining-physiologic-functions
#1
Caroline Manicam, Natarajan Perumal, Norbert Pfeiffer, Franz H Grus, Adrian Gericke
Short posterior ciliary arteries (sPCA) provide the major blood supply to the optic nerve head. Emerging evidence has linked structural and functional anomalies of sPCA to the pathogenesis of several ocular disorders that cause varying degrees of visual loss, particularly anterior ischaemic optic neuropathy and glaucoma. Although the functional relevance of this vascular bed is well-recognized, the proteome of sPCA remains uncharacterized. Since the porcine ocular system closely resembles that of the human's and is increasingly employed in translational ophthalmic research, this study characterized the proteome of porcine sPCA employing the mass spectrometry-based proteomics strategy...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27642593/improvement-in-cerebral-and-ocular-hemodynamics-early-after-carotid-endarterectomy-in-patients-of-severe-carotid-artery-stenosis-with-or-without-contralateral-carotid-occlusion
#2
Jian Wang, Weici Wang, Bi Jin, Yanrong Zhang, Ping Xu, Feixiang Xiang, Yi Zheng, Juan Chen, Shi Sheng, Chenxi Ouyang, Yiqing Li
Purpose. To investigate the alternation in cerebral and ocular blood flow velocity (BFV) in patients of carotid stenosis (CS) with or without contralateral carotid occlusion (CO) early after carotid endarterectomy (CEA). Patients and Methods. Nineteen patients underwent CEA for ≥50% CS. Fourteen patients had the unilateral CS, and five patients had the ipsilateral CS and the contralateral CO. Transcranial Doppler (TCD) and Color Doppler Imaging (CDI) were performed before and early after CEA. Results. In patients with unilateral CS, significant improvements in BFV were observed in anterior cerebral artery (ACA) and middle cerebral artery (MCA) on the ipsilateral side after CEA...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27516038/clinical-and-color-doppler-imaging-features-of-one-patient-with-occult-giant-cell-arteritis-presenting-arteritic-anterior-ischemic-optic-neuropathy
#3
Dragoş Cătălin Jianu, Silviana Nina Jianu, Ligia Petrica, Andrei Gheorghe Marius Motoc, Traian Flavius Dan, Dorela CodruŢa Lăzureanu, Mihnea Munteanu
Anterior ischemic optic neuropathies (AIONs) represent a segmental infarction of the optic nerve head (ONH) supplied by the posterior ciliary arteries (PCAs). Blood supply blockage can occur with or without arterial inflammation. For this reason, there are two types of AIONs: non-arteritic (NA-AION), and arteritic (A-AION), the latter is almost invariably due to giant cell arteritis (GCA). GCA is a primary vasculitis that predominantly affects extracranial medium-sized arteries, particularly the branches of the external carotid arteries (including superficial temporal arteries - TAs)...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27220710/-apply-of-retcam-%C3%A2-and-color-doppler-imaging-in-persistent-hyperplastic-primary-vitreous
#4
Mei Han, Kanxing Zhao, Tongmei Zhang, Yan Li, Jianmin Gao, Liu Dong
OBJECTIVE: To observe the manifestations of RetCam Ⅱ and color Doppler imaging (CDI) in a retrospective case series of persistent hyperplastic primary vitreous (PHPV). METHODS: Retrospective study. The medical records of 9 eyes/9 patients with PHPV went through RetCamⅡ and CDI from 2009 to 2014. RESULTS: There were 6 young boys and 3 young girl in this study, age from 2 months to 5 years. All the patients were born at full term. 9 eyes had complication (cataract)...
May 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/26335631/intracellular-cytoskeleton-and-junction-proteins-of-endothelial-cells-in-the-porcine-iris-microvasculature
#5
Hongfang Yang, Paula K Yu, Stephen J Cringle, Xinghuai Sun, Dao-Yi Yu
Recently we reported studies of the iris microvasculature and its endothelial cells using intra-luminal micro-perfusion, fixation, and silver staining, suggesting that the iris vascular endothelium may be crucial for maintaining homeostasis in the ocular anterior segment. Here we present information regarding the intracellular structure and cell junctions of the iris endothelium. Thirty-seven porcine eyes were used for this study. The temporal long posterior ciliary artery was cannulated to assess the iris microvascular network and its endothelium using intra-luminal micro-perfusion, fixation, and staining with phalloidin for intracellular cytoskeleton f-actin, and with antibodies against claudin-5 and VE-cadherin for junction proteins...
November 2015: Experimental Eye Research
https://www.readbyqxmd.com/read/26334520/anterior-segment-seeding-in-eyes-with-retinoblastoma-failing-to-respond-to-intraophthalmic-artery-chemotherapy
#6
Efthymia Pavlidou, Christopher Burris, Caroline Thaung, Irene Scheimberg, Judith Kingston, John L Hungerford, M Ashwin Reddy, Mandeep S Sagoo
IMPORTANCE: Anterior chamber seeding following intraophthalmic artery chemotherapy is rarely reported. OBJECTIVES: To describe clinicopathologic observations in eyes in which intraophthalmic artery chemotherapy for retinoblastoma failed and to report anterior chamber involvement. OBSERVATIONS: A retrospective case series of 12 enucleated eyes (11 patients) with retinoblastoma refractory to intraophthalmic artery chemotherapy between March 1, 2010, and October 31, 2013, at University College London Institute of Ophthalmology and the Retinoblastoma Service, Royal London Hospital...
December 2015: JAMA Ophthalmology
https://www.readbyqxmd.com/read/26234004/amaurosis-fugax-anterior-ischemic-optic-neuropathy-and-cilioretinal-artery-occlusion-secondary-to-giant-cell-arteritis
#7
Oriel Spierer, Michael Waisbourd
No abstract text is available yet for this article.
June 2015: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/26021973/rat-optic-nerve-head-anatomy-within-3d-histomorphometric-reconstructions-of-normal-control-eyes
#8
Marta Pazos, Hongli Yang, Stuart K Gardiner, William O Cepurna, Elaine C Johnson, John C Morrison, Claude F Burgoyne
The purpose of this study is to three-dimensionally (3D) characterize the principal macroscopic and microscopic relationships within the rat optic nerve head (ONH) and quantify them in normal control eyes. Perfusion-fixed, trephinated ONH from 8 normal control eyes of 8 Brown Norway Rats were 3D histomorphometrically reconstructed, visualized, delineated and parameterized. The rat ONH consists of 2 scleral openings, (a superior neurovascular and inferior arterial) separated by a thin connective tissue strip we have termed the "scleral sling"...
October 2015: Experimental Eye Research
https://www.readbyqxmd.com/read/25904772/anterior-ischemic-optical-neuropathy-in-children-on-chronic-peritoneal-dialysis-report-of-7-cases
#9
Giacomo Di Zazzo, Isabella Guzzo, Lara De Galasso, Michele Fortunato, Giovanna Leozappa, Licia Peruzzi, Enrico Vidal, Ciro Corrado, Enrico Verrina, Stefano Picca, Francesco Emma
BACKGROUND: Anterior ischemic optic neuropathy (AION) is characterized by infarction of the optic nerve head due to hypoperfusion of the posterior ciliary arteries and causes sudden blindness in adults on chronic dialysis, but has rarely been described in children. Unlike adults, children do not have comorbidities related to aging. METHODS: We retrospectively analyzed data of 7 children on nocturnal continuous cycling peritoneal dialysis (CCPD) who developed AION identified within the Italian Registry of Pediatric Chronic Dialysis...
March 2015: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/25711639/a-novel-mgp-cre-knock-in-mouse-reveals-an-anticalcification-antistiffness-candidate-gene-in-the-trabecular-meshwork-and-peripapillary-scleral-region
#10
Teresa Borrás, Matthew H Smith, LaKisha K Buie
PURPOSE: Soft tissue calcification is a pathological condition. Matrix Gla (MGP) is a potent mineralization inhibitor secreted by cartilage chondrocytes and arteries' vascular smooth muscle cells. Mgp knock-out mice die at 6 weeks due to massive arterial calcification. Arterial calcification results in arterial stiffness and higher systolic blood pressure. Intriguingly, MGP was highly abundant in trabecular meshwork (TM). Because tissue stiffness is relevant to glaucoma, we investigated which additional eye tissues use Mgp's function using knock-in mice...
April 2015: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/25596774/surgical-management-of-dysthyroid-diplopia-with-preservation-of-the-anterior-ciliary-vascularization-review-of-ten-cases
#11
B Roussat, W Kilani, N de Preobrajensky, M Berche, L Du Pasquier, M Paques
PURPOSE: During the surgical correction of dysthyroid diplopia, the risk of ischemia by transection of the anterior ciliary arteries is well-known. In order to avoid this, we modified the classical surgical technique: (1) through the preservation of the vascular pedicles during muscle recession and (2) if necessary, through a plication (instead of a resection) of the ipsilateral antagonist muscle. The objective to be achieved is thus the resolution of the diplopia without ischemic complications...
February 2015: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/25405659/posterior-tunica-vasculosa-lentis-and-brittle-star-of-persistent-fetal-vasculature
#12
Marco Pellegrini, Carol L Shields, Sruthi Arepalli, Jerry A Shields
A 17-month-old girl referred for a suspected ciliary body medulloepithelioma was found to have persistent fetal vasculature. Fluorescein angiography showed perfused hyaloid artery posterior tunica vasculosa lentis with brittle star appearance and nonperfused anterior pupillary membrane. Ultrasound biomicroscopy confirmed absence of iris or ciliary body solid tumor.
2014: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/25389879/bilateral-orbital-vasculature-alterations-after-systemic-chemotherapy-and-external-beam-radiation-therapy-treatment-of-advanced-retinoblastoma-implications-for-intraarterial-chemotherapy-management
#13
Hinda Boutrid, Stacey Quintero Wolfe, Timothy G Murray, Yolanda Pina, Roham Moftakhar, Cristina E Fernandes, Jennifer Reichbach, Mohammad Ali Aziz-Sultan
PURPOSE: The purpose of this study was to report significant alterations in orbital vasculature after combined systemic chemoreduction with consolidating external beam radiotherapy treatment in a case of advanced retinoblastoma and to discuss implications for intraarterial melphalan rescue chemotherapy. METHODS: We studied the case of a 22-month-old child who had been treated recently with intraarterial melphalan perfusion after multimodal therapy for advanced intraocular retinoblastoma...
2011: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/24864434/-nonarteritic-ischemic-optic-neuropathy-animal-model-and-its-treatment-applications
#14
REVIEW
Hideki Chuman
Nonarteritic ischemic optic neuropathy (NAION) is one of the most common acute unilaterally onset optic nerve diseases. One management problem in terms of NAION is the difficulty of differential diagnosis between NAION and anterior optic neuritis (ON). A second problem is that there is no established treatment for the acute stage of NAION. A third problem is that there is no preventive treatment for a subsequent attack on the fellow eye, estimated to occur in 15 to 25% of patients with NAION. For differentiation of acute NAION from anterior optic neuritis, we investigated the usefulness of laser speckle flowgraphy (LSFG)...
April 2014: Nippon Ganka Gakkai Zasshi
https://www.readbyqxmd.com/read/24676145/surgical-outcomes-following-rectus-muscle-plication-a-potentially-reversible-vessel-sparing-alternative-to-resection
#15
COMPARATIVE STUDY
Zia Chaudhuri, Joseph L Demer
IMPORTANCE: Extraocular muscle strengthening is a common treatment for strabismus. Plication is an alternative procedure for strengthening muscles with less tissue trauma than resection. OBJECTIVE: To compare the surgical dose effect of plication with that of resection. DESIGN, SETTING, AND PARTICIPANTS: Retrospective comparison of surgical outcomes in an academic pediatric ophthalmology and strabismus practice from July 25, 2005, through March 28, 2013, with a mean follow-up of 137 days for plication and 1243 days for resection...
May 2014: JAMA Ophthalmology
https://www.readbyqxmd.com/read/24631201/effect-of-tamsulosin-on-iris-vasculature-and%C3%A2-morphology
#16
Roni M Shtein, Munira T Hussain, Theresa M Cooney, Victor M Elner, Christopher T Hood
PURPOSE: To determine whether preoperative iris vasculature and morphology are altered in patients who have taken tamsulosin (Flomax). SETTING: Academic multispecialty practice. DESIGN: Case series. METHODS: Patients with current or past tamsulosin use and age- and sex-matched control patients were included. Anterior segment optical coherence tomography (AS-OCT) and iris fluorescein angiography were performed to measure iris vasculature and thickness before cataract surgery...
May 2014: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/24555213/-research-advances-in-the-risk-factors-of-nonarteritic-anterior-ischemic-optic-neuropathy
#17
REVIEW
Ting Chen, Jin Ma, Yang Zhong
As the most common acute optic neuropathy among individuals who are over 50-year old,non arteritic anterior ischemic optic neuropathy ( NAION) is presumed result from a circulatory insufficiency,or infarct, within the lamina or retrolaminar portion of the optic nerve head that is supplied by the short posterior ciliary arteries. It usually presents with sudden painless unilateral visual loss, characterized visual field defects, relative afferent papillary defect and pallid optic disk edema. The exact etiology of NAION remains elusive...
November 2013: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/24477744/massive-anterior-chamber-involvement-after-intra-arterial-chemotherapy-for-retinoblastoma-ultrasound-biomicroscopy-and-histopathology
#18
Sonia De Francesco, Francesco Pichi, Andrea Lembo, Domenico Mastrangelo, Anna Paradiso, Mariacarla De Luca, Paolo Toti, Paolo Nucci, Theodora Hadjistilianou
This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement after treatment with intra-arterial chemotherapy. UBM was used to document tumour pseudohypopion, cells in the aqueous humor, implanted clusters of cells on the corneal endothelium, iris nodules, lens capsule deposits and ciliary body invasion. The UBM data, compared with the histopathologic analysis, performed on eye tissue, after enucleation of the affected eye, revealed a significant concordance...
August 2014: International Ophthalmology
https://www.readbyqxmd.com/read/24386788/-ocular-ischemic-syndrome-a-case-report
#19
M Zemba, Corina Ioana Avram, Uliana Ochinciuc, Alina Cristina Stamate, Raluca Lăcrămioara Camburu
Ocular ischemic syndrome, also known as hypoperfusion/ hypotensive retinopathy or as ischemic oculopathy is a rare ocular disease determined by chronic arterial hypoperfusion through central retinal artery, posterior and anterior ciliary arteries. It is bilateral in 20% of the cases. Most often it appears due to severe occlusion of the carotid arteries (ICA, MCA>ECA), described in 1963 by Kearns and Hollenhorst. Occasionally it can be determined by the obstruction of ophtalmic artery or some arterities (Takayasu, giant cell arteritis)...
2013: Oftalmologia
https://www.readbyqxmd.com/read/24242220/cataract-formation-a-possible-complication-of-intra-arterial-chemotherapy-for-retinoblastoma
#20
Daniela Suesskind, Merle Schrader, Michael H Foerster, Ulrike Ernemann, Sabine Aisenbrey
PURPOSE: To delineate and discuss a not yet described possible ocular complication of selective intra-arterial chemotherapy (SIAC) for treatment of retinoblastoma. METHODS: A 23-month-old girl with a large unilateral retinoblastoma was treated with repeated SIAC using 5 mg melphalan between July 2010 and January 2012. Clinical course of tumor and further ocular changes after therapy and histopathologic findings are described. RESULTS: In total, 5 SIAC were performed over a time period of 18 months...
May 2014: European Journal of Ophthalmology
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