Lifang Sun, Yurun Miao, Zhenzhong Wang, Huan Chen, Panpan Dong, Hong Zhang, Linjiao Wu, Meiqin Jiang, Lifei Chen, Wendi Yang, Pingdong Lin, Dingding Jing, Zhipu Luo, Yongqiang Zhang, Yong-Sam Jung, Xiaodong Wu, Yingjuan Qian, Yunkun Wu
African Swine Fever (ASF) is a highly contagious viral haemorrhagic disease of swine, leading to enormous economic losses in the swine industry. However, vaccines and drugs to treat ASF have yet to be developed. African swine fever virus (ASFV) encodes more than 150 proteins, but 50% of them have unknown functions. Here, we present the crystal structure of the ASFV I73R protein at a resolution of 2.0 Å. Similar search tools based solely on amino acid sequence shows that it has no relationships to any proteins of known function...
March 21, 2022: Transboundary and Emerging Diseases