Alberto Romano, Fabrizio Sollazzo, Serena Rivetti, Lorenzo Morra, Tiziana Servidei, Donatella Lucchetti, Giorgio Attinà, Palma Maurizi, Stefano Mastrangelo, Isabella Carlotta Zovatto, Riccardo Monti, Massimiliano Bianco, Vincenzo Palmieri, Antonio Ruggiero
In recent decades, the improvement of treatments and the adoption of therapeutic protocols of international cooperation has led to an improvement in the survival of children affected by brain tumors. However, in parallel with the increase in survival, long-term side effects related to treatments have been observed over time, including the activation of chronic inflammatory processes and metabolic alterations, which can facilitate the onset of metabolic syndrome and increased cardiovascular risk. The aim of this study was to find possible statistically significant differences in the serum concentrations of early biomarkers of metabolic syndrome and in the results of cardiopulmonary exercise testing between survivors of childhood brain tumors and healthy controls...
January 11, 2024: Cancers