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Eosinophilic panniculitis

Keisuke Goto, Sumiko Ishizaki, Keiji Tanese, Yoshimi Oshitani, Yo Kaku, Rie Kaneko, Hiromichi Takama, Misawo Ishikawa, Masaru Tanaka
Nonepisodic angioedema with eosinophilia (NEAE) is a rare condition characterized with monoepisodic angioedema, a nonfebrile state, eosinophilia, normal serum IgM levels, and lack of internal organ involvement. The histology of this disease is not yet well known. The purpose of this study was to characterize the histopathologic features of NEAE. Twelve cases of clinically confirmed NEAE were retrieved from 6 institutions, and these cases were reviewed regarding the clinical data and histopathology, particularly regarding granulomatous lesions...
February 2016: American Journal of Dermatopathology
James W Bush, Emily Himes, Deede Liu, Garth R Fraga
No abstract text is available yet for this article.
February 2015: Journal of Cutaneous Pathology
Sonia Jain, Pramod Jain, Preeti Jakhar, V B Shivkumar
Eosinophilic panniculitis (EP) is characterized by prominent infiltration of subcutaneous fat with eosinophils. The etiology is diverse. This is not a disease but represents a reaction pattern that may occur in a variety of circumstances. The exact pathogenesis of the disease is still unclear. We present the case of a 6-year-old girl child who was diagnosed with EP.
January 2015: Indian Dermatology Online Journal
Mohamed El-Khalawany, Sameh Fawzy, Asmaa Saied, Mohammed Al Said, Ahmed Amer, Bayoumi Eassa
Although dermal fillers are generally accepted as safe and well-tolerable cosmetic tools, adverse reaction still forms a prognostic problem. The aim of this study was to demonstrate the clinicopathologic patterns of dermal filler complications in our center. A 5-year single-center study that included patients complained from filler complications and referred to the dermatopathology unit in Al-Azhar University for histologic assessment. The study included 38 female patients with an average age of 47 years. The mean onset of complications was 14...
February 2015: Annals of Diagnostic Pathology
Satoshi Fukuda, Youichi Miyaoka, Kousuke Tsukano, Sayaka Ueno, Daisuke Izumi, Satoshi Yamanouchi, Tomotaka Yazaki, Takayuki Sonoyama, Satoko Ito, Hirofumi Fujishiro, Naruaki Kohge, Tomonori Imaoka
A 53-year-old female who complained of constipation and abdominal fullness was referred to our hospital. A tender low abdominal mass was palpable. Imaging (abdominal ultrasonography, CT, and MRI) revealed that the tumor had spread to the mesosigmoid and the superior mesentery. The tumor was very difficult to diagnose on the basis of imaging alone. Therefore, we obtained a biopsy at the time of laparotomy for definitive diagnosis. The biopsy showed extensive fibrosis and lymphocyte, plasma cell, and eosinophil infiltration in the associated adipose tissue...
December 2014: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
Gonzalo Labarca, Renatta de Grazia, Pamela Turrillas
No abstract text is available yet for this article.
February 2, 2015: Medicina Clínica
Nootchanard Mahamaytakit, Srisupalak Singalavanija, Wanida Limpongsanurak
Basidiobolus ranarum is an uncommon subcutaneous zygomycosis mostly found in immunocompetent children in tropical countries. Presence of slow growing non-tender, non-inflammatory, subcutaneous swelling that does not spread beyond the subcutaneous tissue are classic clinical features. The authors report two cases of subcutaneous zygomycosis which tissue cultures were positive for Basidiobolus ranarum. The first case was a 10-months-old boy presented with prolonged high fever and a rapidly expanding ulcerated plaque unresponsive to systemic antibiotic...
June 2014: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Didac Barco, Maria A Barnadas, Esther Roé, Francisco J Sancho, Elena Ricart, Agustín Alomar
We report the case of a 75-year old woman with collagenous colitis who presented with erythematous and edematous plaques on the periorbital and eyelid regions, accompanied by oral ulcers. Histopathology showed a dermal neutrophilic infiltrate plus mild septal and lobular panniculitis with lymphocytes, neutrophils and eosinophils. Five years earlier she had presented a flare of papules and vesicles on the trunk, together with oral ulcers; a skin biopsy revealed a neutrophilic dermal infiltrate and Sweet's syndrome was diagnosed...
January 18, 2010: Dermatology Reports
Rosa María Fernández-Torres, Susana Castro, Ana Moreno, Roberto Alvarez, Eduardo Fonseca
We report a case of subcutaneous histiocytoid Sweet syndrome in an adolescent with Crohn disease. A 14-year-old boy with a 1-year history of ileocolonic and perianal Crohn disease, treated with infliximab and azathioprine, was admitted to the Pediatrics Department with malaise, abdominal pain, bloody diarrhea, and fever (39°C) from 15 days ago. Two days later, he developed cutaneous lesions consisting of tender, erythematous, and violaceous papules and nodules scattered over his legs, soles, and upper extremities...
2014: Case Reports in Dermatological Medicine
G Borroni, S Torti, R M D'Ospina, C Pezzini
A substantial number of all panniculitides fails to recognize a specific etiology, and that is true also for a relatively frequent type of panniculitis, such as erythema nodosum (EN). Between the recognized causative factors of panniculitides, infectious, physical agents, autoimmune mechanisms and neoplastic disorders are well known. On the contrary, the role of drugs as inducers of panniculitides is marginally considered, and their report limited to anecdotal observations, often without due histopathological support...
April 2014: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Shi-Jun Shan, Ying Guo
Sclerosing lipogranuloma is a granulomatous reaction to the injection of a high-viscosity fluid in the tissues for the cosmetic purpose of improving body contour; lesions on the extremities and buttocks are commonly the results of injections of therapeutic agents in oily vehicles. Exenatide, once-weekly injection, is a therapeutic method for patients with type 2 diabetes. Here, we describe a case of exenatide once weekly induced eosinophilic sclerosing lipogranuloma at the injection site of a 62-year-old patient...
June 2014: American Journal of Dermatopathology
Tomás A Orduna, Susana C Lloveras, Sofía E Echazarreta, Santiago L Garro, Gustavo D González, Claudia C Falcone
We describe a case of a 32-year-old man, resident in Buenos Aires, with dermatologic manifestations compatible with gnathostomiasis. The patient had traveled to Colombia in the month prior to the onset of symptoms. There, he repeatedly ate ceviche (raw fish marinated in lemon juice). He presented with an erythematous migratory panniculitis accompanied by eosinophilia. He underwent skin biopsy of a lesion and pathological diagnosis was "eosinophilic panniculitis". The triad of migratory panniculitis, eosinophilia and consume of raw fish during the trip to Colombia was suggestive of gnathostomiasis...
2013: Medicina
Shannon N S Cerveny, Michelle E Thompson, Sarah M Corner, Amy K Swinford, Rob L Coke
A 16-yr-old male clouded leopard (Neofelis nebulosa) was presented for lethargy and anorexia. A cutaneous abdominal mass extending from the pubis to just caudal to the xiphoid process was present. A biopsy revealed histologic lesions consistent with an atypical mycobacterial infection consisting of diffuse, severe, pyogranulomatous dermatitis and panniculitis, with clear vacuoles and 3-5 microm, intravacuolar, faintly eosinophilic, filamentous bacilli that stained positively with FiteFaraco modified acid-fast stain...
September 2013: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
S Grassi, R G Borroni, V Brazzelli
This paper will give a comprehensive view of the most frequent panniculitides seen in childhood, with emphasis on the types exclusively found in infancy, and for all other types of panniculitides also found in adults. Aim of this paper is also to analyze the clinical differences between panniculitis in childhood and in adulthood, and to give reliable histopathologic criteria for a specific diagnosis. A review of the literature is here integrated by authors' personal contribution. Panniculitides in children is a heterogeneous group of diseases, as well as in adult life, characterized by inflammation of the subcutaneous fat...
August 2013: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
George P Sarantopoulos, Beth Palla, Jonathan Said, Marsha C Kinney, Steven M Swerdlow, Rein Willemze, Scott W Binder
The Society for Hematopathology and European Association for Haematopathology workshop, from October 27 to 29, 2011, in Los Angeles, CA, exhibited many exemplary skin biopsy specimens with interesting inflammatory changes mimicking features of cutaneous lymphoma. This article reviews features observed in cutaneous lymphoid hyperplasia, cutaneous drug reactions, lupus-associated panniculitis, pityriasis lichenoides, hypereosinophilic syndrome, histiocytic necrotizing lymphadenitis, traumatic ulcerative granuloma with stromal eosinophils, and pigmented purpuric dermatosis, as well as a brief review of the pertinent literature and discussion of submitted conference cases...
April 2013: American Journal of Clinical Pathology
Raegan D Hunt, Maria Robinson, Rishi Patel, Andrew G Franks
A 60-year-old man presented with intermittent, tender, erythematous nodules on the legs that were associated with mild arthralgias. He was otherwise asymptomatic but reported a history of lupus anticoagulant antibodies that were discovered incidentally on laboratory screening at the approximate time that his lesions first occurred. A biopsy specimen showed a septal and lobular panniculitis with neutrophils, histiocytes, numerous eosinophils, foci of fibrosis, and fat necrosis but no vascular pathology. An elevated activated partial thromboplastin time (PTT), appreciably elevated levels of anti-beta-2 glycoprotein I antibody (IgM and IgG), and moderately elevated levels of anticardiolipin antibody (IgM and IgG) were present...
December 2012: Dermatology Online Journal
Pelin Ustuner, Nursel Dilek, Yunus Saral, Aziz Ramazan Dilek, Recep Bedir
UNLABELLED: HASH(0x4709318) INTRODUCTION: Eosinophilic panniculitis is an unusual type of panniculitis characterized by a prominent infiltration of subcutaneous fat with eosinophils without an exact etiopathogenesis. To the best of our knowledge, up to now eosinophilic panniculitis has been described in only one previous case with human immunodeficiency virus disease in the literature. CASE PRESENTATION: Here we report the case of a 44-year-old Caucasian man, who is human immunodeficiency virus positive, diagnosed with eosinophilic panniculitis...
2012: Journal of Medical Case Reports
Alvaro C Laga, Cecilia Lezcano, César Ramos, Humberto Costa, César Chian, César Salinas, Martin Salomon, Manuel del Solar, Francisco Bravo
BACKGROUND: Cutaneous gnathostomiasis is an emerging food-borne parasitic zoonosis. Histopathological demonstration of the larva on random biopsy specimen of erythematous plaques is infrequent because of its migrating nature. OBJECTIVE: We sought to determine whether medical treatment with albendazole or ivermectin increases the diagnostic yield of skin biopsy specimen. METHODS: A retrospective chart review was conducted in a private dermatology practice in Lima, Peru...
February 2013: Journal of the American Academy of Dermatology
M Zöller, S Silinski, C Ludwig, M Weig, K Mätz-Rensing, F-J Kaup
An adult male mandrill (Mandrillus sphinx) suffered from chronic ulceration of the facial and gluteal skin and the oral and nasal mucosa. The ulcers were resistant to therapy and led to deterioration in the general condition of the animal. Microscopical examination revealed a severe, chronic, multifocal, granulomatous and eosinophilic dermatitis and panniculitis. There was also stomatitis and rhinitis with numerous intralesional fungal elements. These organisms were identified by immunohistochemistry, transmission electron microscopy, polymerase chain reaction and fungal culture as Candida albicans...
August 2012: Journal of Comparative Pathology
Mayra Carrijo Rochael, Luciana Pantaleão, Enoï A Guedes Vilar, Luciana Helena Zacaron, Eduardo Quelhas Spada, Marcus H S B Xavier, Karla Strong Rodrigues
BACKGROUND: Sweet's syndrome refers to a set of cutaneous, systemic and histopathological alterations that occur in response to different stimuli, in a similar way to that occurring in erythema nodosum, erythema multiforme and leukocytoclastic vasculitis. The syndrome has been described in association with conditions such as infections, pregnancy, the use of certain medications and malignancy. OBJECTIVES: To evaluate the clinical and histopathological alterations occurring in this syndrome and to assess the association between these alterations and other conditions...
July 2011: Anais Brasileiros de Dermatologia
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