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Montreal cognitive assessment MOCA

Matthew Swan, Nancy Doan, Robert A Ortega, Matthew Barrett, William Nichols, Laurie Ozelius, Jeannie Soto-Valencia, Sarah Boschung, Andres Deik, Harini Sarva, Jose Cabassa, Brooke Johannes, Deborah Raymond, Karen Marder, Nir Giladi, Joan Miravite, William Severt, Rivka Sachdev, Vicki Shanker, Susan Bressman, Rachel Saunders-Pullman
Mutations in GBA1 are a well-established risk factor for Parkinson disease (PD). GBA-associated PD (GBA-PD) may have a higher burden of nonmotor symptoms than idiopathic PD (IPD). We sought to characterize the relationship between GBA-PD and neuropsychiatric symptoms. Subjects were screened for common GBA1 mutations. GBA-PD (n=31) and non-carrier (IPD; n=55) scores were compared on the Unified Parkinson Disease Rating Scale (UPDRS), Montreal Cognitive Assessment (MoCA), Beck Depression Inventory (BDI), and the State-Trait Anxiety Index (STAI)...
November 15, 2016: Journal of the Neurological Sciences
Serap Argun Baris, Dilek Tuncel, Cigdem Ozerdem, Huseyin Kutlu, Tugba Onyilmaz, Ilknur Basyigit, Hasim Boyaci, Fusun Yildiz
BACKGROUND: The aim of this study is to evaluate the presence of neurocognitive dysfunctions, depression and anxiety and the effect of positive airway pressure (PAP) therapy on these alterations in Obesity Hypoventilation Syndrome (OHS) patients. METHODS: Ten healthy normal and obese controls, 10 OHS and 10 OSAS patients were included in the study. Short form-36, Beck Depression Scale and State-Trade Anxiety Inventory (STAI 1-2) were performed. Wisconsin Card Sorting Test (WCST), Montreal Cognitive Assessment Scale (MOCA), Enhanced Cued Recall (ECR) and Mini Mental Test (MMT) were used for neurocognitive evaluation...
2016: Multidisciplinary Respiratory Medicine
Hirochika Ryuno, Kei Kamide, Yasuyuki Gondo, Mai Kabayama, Ken Sugimoto, Takeshi Nakagawa, Kazunori Ikebe, Hiroki Inagaki, Yukie Masui, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi
OBJECTIVE: It is well-documented that midlife hypertension (HT) is associated with decline of cognitive function. Recently, we reported that the influence of HT and/or elevated blood pressure on the progression of cognitive decline was attenuated at late life aged 70 of the general population in cross-sectional analysis. The purpose of this study is to investigate the 3 years' longitudinal effect of HT and additive risk factors on decline of cognitive function for 70-year-old general Japanese population in the Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) study, which is a narrow age range cohort...
September 2016: Journal of Hypertension
Lindsay S Nagamatsu, Chun Liang Hsu, Jennifer C Davis, John R Best, Teresa Liu-Ambrose
: Background/Study Context: With our aging population, understanding determinants of healthy aging is a priority. One essential component of healthy aging is mobility. Although self-efficacy can directly impact mobility in older adults, it is unknown what role brain health may play in this relationship. METHODS: The authors conducted a cross-sectional pilot analysis of community-dwelling women (N = 80, mean age = 69 years) to examine whether brain volume mediates the relationship between falls-related self-efficacy, as measured by the Activities-specific Balance Confidence (ABC) scale, and mobility, as measured by the Timed Up and Go (TUG) test...
October 2016: Experimental Aging Research
Taiji Ogawa, Masahiro Uota, Kazunori Ikebe, Yasumichi Arai, Kei Kamide, Yasuyuki Gondo, Yukie Masui, Tatsuro Ishizaki, Chisato Inomata, Hajime Takeshita, Yusuke Mihara, Kodai Hatta, Yoshinobu Maeda
The sense of taste plays a pivotal role for personal assessment of the nutritional value, safety, and quality of foods. Although it is commonly recognized that taste sensitivity decreases with age, alterations in that sensitivity over time in an old-old population have not been previously reported. Furthermore, no known studies utilized comprehensive variables regarding taste changes and related factors for assessments. Here, we report novel findings from a 3-year longitudinal study model aimed to elucidate taste sensitivity decline and its related factors in old-old individuals...
October 17, 2016: Journal of Oral Rehabilitation
Yi-Jen Wu, Philip Tseng, Han-Wei Huang, Jon-Fan Hu, Chi-Hung Juan, Kuei-Sen Hsu, Chou-Ching Lin
Diabetes mellitus can lead to diabetic polyneuropathy (DPN) and cognitive deficits that manifest as peripheral and central neuropathy, respectively. In this study we investigated the relationship between visuospatial working memory (VSWM) capacity and DPN severity, and attempted to improve VSWM in DPN patients via the use of transcranial direct current stimulation (tDCS). Sixteen DPN patients and 16 age- and education-matched healthy control subjects received Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Montreal Cognitive Assessment (MOCA) for baseline cognitive assessment...
2016: Frontiers in Human Neuroscience
Kelly A Mills, Zoltan Mari, Gregory M Pontone, Alexander Pantelyat, Angela Zhang, Nadine Yoritomo, Emma Powers, Jason Brandt, Ted M Dawson, Liana S Rosenthal
BACKGROUND: In Parkinson's disease, the association between objective and patient-reported measures of cognitive dysfunction is unknown and highly relevant to research and clinical care. OBJECTIVE: To determine which cognitive domain-specific Montreal Cognitive Assessment (MoCA) subscores are most strongly associated with patient-reported cognitive impairment on question 1 (Q1) of the Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS)...
September 27, 2016: Parkinsonism & related Disorders
N A Trusova, O S Levin, A V Arablinsky
AIM: To study clinical/neuropsychological and neuroimaging characteristics of Alzheimer's disease in the combination with cerebrovascular disease (CVD). MATERIAL AND METHODS: Ninety patients with dementia, including 35 patients with AD, 35 patients with mixed dementia (MD) and 20 patients with vascular dementia, were examined. The character of dementia was established according to NINCDS-ADRDA and NINDS-AIREN criteria. The neuropsychological battery included Addenbrooke's Cognitive Examination (ACE-R), Montreal Cognitive Assessment scale (MoCA), fluency test and the visual memory test (SCT)...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
D A Gutorova, E E Vasenina, O S Levin
AIM: To determine sensitivity and specificity of the 3-CT scale, a combination of 3 simple and minimum cost tests, for screening purposes in old and old-old patients in comparison to the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE). MATERIAL AND METHODS: The study included 106 patients. Assessment of sensitivity and specificity of neuropsychological testing with ROC-curves was used. RESULTS: MoCA showed moderate sensitivity (0...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
T A Polyakova, O S Levin
AIM: To study a role of cerebral microbleeds (CMB) in the diagnosis of main cerebrovascular and neurodegenerative diseases with cognitive impairment. MATERIAL AND METHODS: CMB were studied in 120 patients with Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and vascular dementia using 1.5T MRI in T2 * gradient echo. An impact of CMB on cognitive functions and the relationship with signs of vascular and neurodegenerative lesions of the brain were studied as well...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Sabrina Castellano, Andrea Ventimiglia, Salvatore Salomone, Andrea J Ventimiglia, Simona De Vivo, Maria Salvina Signorelli, Elisa Bellelli, Mario Santagati, Rita Anna Cantarella, Enrica Fazio, Eugenio Aguglia, Filippo Drago, Santo Di Nuovo, Filippo Caraci
BACKGROUND: Major Depressive disorder (MDD) is often accompanied by cognitive deficits, involving attention, learning, memory and executive functioning. Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin and Noradrenaline Reuptake Inhibitors (SNRIs) show efficacy on affective symptoms, but it is unclear whether or not they improve cognitive symptoms. METHODS: We carried out a 12 week-prospective observational study in two cohorts of recurrent moderate-severe partial responder MDD patients, to test the hypothesis that SSRIs and/or SNRIs may affect cognitive symptoms and assess whether or not such an effect was correlated to their effect on affective symptoms...
October 3, 2016: CNS & Neurological Disorders Drug Targets
A J Larner
BACKGROUND/AIMS: Calculation of correlation coefficients is often undertaken as a way of comparing different cognitive screening instruments (CSIs). However, test scores may correlate but not agree, and high correlation may mask lack of agreement between scores. The aim of this study was to use the methodology of Bland and Altman to calculate limits of agreement between the scores of selected CSIs and contrast the findings with Pearson's product moment correlation coefficients between the test scores of the same instruments...
October 6, 2016: Dementia and Geriatric Cognitive Disorders
Joonbum Lee, Bruce Mehler, Bryan Reimer, Kazutoshi Ebe, Joseph F Coughlin
OBJECTIVE: Research has established that long off-road glances increase crash risk, and other work has shown increased off-road glance behavior in older drivers. This study investigated the relationship between older drivers' (M = 66.3, range 61-69 years) cognitive abilities and the duration of off-road glances while engaged in secondary visual-manual activities. METHOD: Twenty-two drivers completed the Montreal Cognitive Assessment (MoCA) prior to driving an instrumented vehicle and completing a set of radio-tuning tasks...
October 3, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
Vincent Auffret, Francisco Campelo-Parada, Ander Regueiro, María Del Trigo, Olivier Chiche, Chekrallah Chamandi, Ricardo Allende, Juan G Cordoba-Soriano, Jean-Michel Paradis, Robert De Larochellière, Daniel Doyle, Eric Dumont, Siamak Mohammadi, Mélanie Côté, Alier Marrero, Rishi Puri, Josep Rodés-Cabau
BACKGROUND: Data regarding the mid- to long-term cognitive trajectory of transcatheter aortic valve (TAVR) recipients are scarce. OBJECTIVES: Changes in global cognition and specific cognitive domains up to 1 year post-TAVR were evaluated. METHODS: Fifty-one patients (median age 80.0 [interquartile range: 72.0 to 85.0] years; 37% women) underwent TAVR and prospective assessment of cognitive function using the Montreal Cognitive Assessment (MoCA) at baseline, short-term (30 days), and 1 year post-TAVR...
September 22, 2016: Journal of the American College of Cardiology
Siting Chen, Xuyang Zuo, Yuan Li, Tian Jiang, Nan Zhang, Fang Dai, Qiu Zhang
AIM: The aim of this research is to study the ghrelin level, executive function, and their possible association in patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: 370 people were recruited between March 2015 and March 2016 in this study. Among them, 212 subjects were patients with T2DM and 158 subjects were included as control group. Their blood sample was analyzed for the level of ghrelin and other clinical indexes. Cognitive function was measured by Montreal Cognitive Assessment (MoCA) and executive function was evaluated by Wisconsin Card Sorting Test (WCST)...
September 30, 2016: Journal of Diabetes Investigation
Iwona Bojar, Jarosław Pinkas, Anna Wierzbińska-Stępniak, Dorota Raczkiewicz, Alfred Owoc, Mariusz Gujski
BACKGROUND The goal of this study was to investigate the relationship between cognitive functions and the level of endogenous estradiol in postmenopausal women, according to which estrogen receptor α (ERα) polymorphism the woman carries. MATERIAL AND METHODS The study group consisted of 210 women. The inclusion criteria were: minimum 2 years after the last menstruation, FSH concentration 30 U/ml, and no dementia signs on Montreal Cognitive Assessment (MoCA). A computerized battery of Central Nervous System Vital Signs (CNS VS) test was used to diagnose cognitive functions...
September 28, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Luqman Helmi, David Meagher, Edmond O'Mahony, Donagh O'Neill, Owen Mulligan, Sutha Murthy, Geraldine McCarthy, Dimitrios Adamis
AIM: To explore the agreement between the mini-mental state examination (MMSE) and montreal cognitive assessment (MoCA) within community dwelling older patients attending an old age psychiatry service and to derive and test a conversion formula between the two scales. METHODS: Prospective study of consecutive patients attending outpatient services. Both tests were administered by the same researcher on the same day in random order. RESULTS: The total sample (n = 135) was randomly divided into two groups...
September 22, 2016: World Journal of Psychiatry
Charles Van Liew, Maya S Santoro, Jody Goldstein, Shea Gluhm, Paul E Gilbert, Jody Corey-Bloom
We sought to investigate whether the Montreal Cognitive Assessment (MoCA) could provide a brief assessment of recall and recognition using Huntington disease (HD) and Alzheimer disease (AD) as disorders characterized by different memory deficits. This study included 80 participants with HD, 64 participants with AD, and 183 community-dwelling control participants. Random-effects hierarchical logistic regressions were performed to assess the relative performance of the normal control (NC), participants with HD, and participants with AD on verbal free recall, cued recall, and multiple-choice recognition on the MoCA...
September 26, 2016: American Journal of Alzheimer's Disease and Other Dementias
Nathalie Ribeiro Artigas, Giovana Duarte Eltz, Alexandre Severo do Pinho, Vanessa Bielefeldt Leotti Torman, Arlete Hilbig, Carlos R M Rieder
Background. Changes in proprioception may contribute to postural instability in individuals with neurological disorders. Objectives. Evaluate proprioception in the lower limbs of patients with Parkinson's disease (PD) and the association between proprioception and cognitive ability, motor symptoms, postural instability, and disease severity. Methods. This is a cross-sectional, controlled study that evaluated proprioception in PD patients and healthy age- and sex-matched individuals. Kinetic postural proprioception of the knee was evaluated using an isokinetic dynamometer (Biodex® Multi-Joint System 4 Pro)...
2016: Neuroscience Journal
Ziad Samir Nasreddine, Bhavini Bhovan Patel
UNLABELLED: Objective background: The Montreal Cognitive Assessment (MoCA) is a questionnaire that has been developed to help physicians around the world diagnose a patient's cognitive ability. Available in multiple languages and for use in multiple countries worldwide, the goal of this study was to validate the alternate versions 2 and 3 of the French MoCA test to assist physicians in the detection of mild cognitive impairment (MCI), while decreasing the learning effect upon frequent testing...
September 2016: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
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