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https://www.readbyqxmd.com/read/27921090/the-effect-of-intrauterine-human-chorionic-gonadotropin-injection-before-embryo-transfer-on-the-implantation-and-pregnancy-rate-in-infertile-patients-a-randomized-clinical-trial
#1
Razieh Dehghani Firouzabadi, Sima Janati, Mohammad Hossein Razi
BACKGROUND: Implantation is one of the essential steps for the success of assisted reproductive techniques (ART). Their success depends on three main factors: embryo quality, endometrial receptivity (ER), and synchrony between embryo and endometrium. There are various factors that regulate the complex process of implantation. In this regard, one may refer to human chorionic gonadotropin (hCG) as the most important factor. OBJECTIVE: This study aims to investigate the effect of intrauterine hCG injection before embryo transfer (ET) on pregnancy outcome in infertile couples...
October 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27916070/-effect-of-luteal-phase-gonadotropin-releasing-hormone-agonist-administration-on-pregnancy-outcome-in-ivf-icsi-cycles-a-systematic-review-and-meta-analysis
#2
L P Yu, N Liu, Y Liu
Objective: To evaluate the potential efficacy and safety of gonadotropin-releasing hormone agonist(GnRH-a) administration in the luteal-phase on in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles in assisted reproductive technology (ART). Methods: The relevant papers published before November 2015 were electronically searched in PubMed, EMBASE, Cochrane Library, WHO ICTRP, ClinicalTrials.gov, CNKI, CBM and WanFang database to collect randomized controlled trial (RCT) involving GnRH-a administration in the luteal-phase on IVF/ICSI cycles in ART...
November 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27908224/serum-substance-p-concentrations-to-predict-oocyte-maturation-index-and-clinical-pregnancy
#3
Yavuz Sahin, Enis Özkaya, Semra Kayatas Eser, Tayfun Kutlu, Ilhan Sanverdi, Gulden Tunali, Ates Karateke
AIM: The aim of this study was to assess the predictive value of serum substance P (SP) concentrations on oocyte maturation and clinical pregnancy. METHODS: Ninety-three women with unexplained infertility underwent intracytoplasmic sperm injection (ICSI) cycles. Antagonist protocol was started for each participant and at the day of oocyte pick up, serum samples were obtained from each participant to assess SP concentrations, and these concentrations were utilized to predict mature/total oocyte ratio and clinical pregnancy...
December 2, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27881336/-outcome-analysis-of-monozygotic-twin-pregnancy-conceived-by-assisted-reproductive-techniques
#4
Shu-Xian Feng, Xue-Lan Li, Xing-Yu Zhou, Yu-Dong Liu, Ping-Ping Guo, De-Sheng Ye, Xin Chen, Shi-Ling Chen
OBJECTIVE: To analyze the incidence, management, and outcomes of monozygotic twin (MZT) pregnancy conceived by assisted reproductive techniques (ART). METHODS: A retrospective analysis was performed of clinical pregnancies after in vitro fertilization and embryo transfer (IVF-ET) and introcytoplasmic sperm injection and embryo transfer (ICSI-ET) from January, 2010 to June 2015 at our center. We investigated the incidence, managements and outcomes of 94 MZT pregnancies...
November 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/27876421/prognostic-factors-for-patients-undergoing-vitrified-warmed-human-embryo-transfer-cycles-a-retrospective-cohort-study
#5
Toshifumi Takahashi, Ayumi Hasegawa, Hideki Igarashi, Mitsuyoshi Amita, Jun Matsukawa, Isao Takehara, Satoko Suzuki, Satoru Nagase
We examined the prognostic factors for pregnancy in 210 vitrified-warmed embryo transfer (ET) cycles in 121 patients. The univariate analysis showed that age, gravida, the number of cycles associated with infertility caused by endometriosis, the number of previous assisted reproductive technology (ART) treatment cycles, and the number of ICSI procedures were significantly lower in pregnant cycles compared with non-pregnant cycles. The percentages of ET using at least one intact embryo and of ET using at least one embryo that had developed further after warming were significantly higher in pregnant cycles compared with non-pregnant cycles...
November 23, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27852097/subclinical-hypothyroidism-and-intracytoplasmic-sperm-injection-outcomes
#6
Marcela de Alencar Coelho Neto, Wellington de Paula Martins, Anderson Sanches de Melo, Rui Alberto Ferriani, Paula Andrea Navarro
Purpose Whether preconception elevated concentrations of thyroid-stimulating hormone (TSH) compromises reproductive outcomes in patients undergoing assisted reproduction techniques (ARTs) remains unclear. This study therefore compared the reproductive outcomes in patients with TSH concentrations of < 2.5 mIU/L, 2.5-4.0 mIU/L, and 4.0-10.0 mIU/L undergoing controlled ovarian stimulation (COS) for in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). Methods This retrospective cohort study evaluated the medical records of all women with measured TSH concentrations who underwent IVF/ICSI between January 2011 and December 2012...
November 16, 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/27846734/reproductive-technologies-and-the-risk-of-congenital-heart-defects
#7
Satoru Iwashima, Takamichi Ishikawa, Hiroaki Itoh
Assisted reproductive technology (ART) has become widespread, accounting for ∼2% of all births worldwide, with a similar proportion in Japan. Our goal was to determine whether ART is associated with an increased risk of congenital heart defect (CHD). The study subjects were 2716 pregnant women (2317 in a spontaneous conception [SC] group and 399 in an assisted conception [AC] group). Of patients in the AC group, 142 were treated with ovulation-inducing agents (OIAs), 56 with artificial insemination by the husband (AIH), 159 with in vitro fertilization (IVF), and 42 with intracytoplasmic sperm injection (ICSI)...
November 16, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27832397/optimal-embryo-transfer-strategy-in-poor-response-may-include-freeze-all
#8
Murat Berkkanoglu, Kevin Coetzee, Hasan Bulut, Kemal Ozgur
PURPOSE: In this retrospective cohort study, we investigated the best embryo transfer strategy in ICSI cycles with ≤4 oocytes collected at oocyte retrieval. METHODS: Women who underwent antagonist co-treatment COS for ICSI treatment between January 2010 and December 2015 at a private ART clinic (N = 2263). Eight hundred seventy-nine women (group 1) had ≤4 oocytes collected at oocyte retrieval, of whom 645 (group A) had cleavage stage embryo transfer (ET), and 234 (group B) had blastocyst ET...
November 10, 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27824942/identifying-maternal-constraints-on-fetal-growth-and-subsequent-perinatal-outcomes-using-a-multiple-embryo-implantation-model
#9
Nigel Pereira, Tyler Cozzubbo, Stephanie Cheung, Zev Rosenwaks, Gianpiero D Palermo, Queenie V Neri
INTRODUCTION: Although the majority of singleton births after in vitro fertilization (IVF) are uncomplicated, studies have suggested that IVF pregnancies may be independently associated with low birth weight (LBW), preterm birth (PTB), and perinatal mortality. These outcomes complicate multiple gestations as expected, but have also been reported in singletons. A multiple embryo implantation model allows for assessment of the early in utero environment, and therefore, assessment of any maternal constraints on developing fetuses...
2016: PloS One
https://www.readbyqxmd.com/read/27822908/the-duration-of-gonadotropin-stimulation-does-not-alter-the-clinical-pregnancy-rate-in-ivf-or-icsi-cycles
#10
N Purandare, G Emerson, C Kirkham, C Harrity, D Walsh, E Mocanu
BACKGROUND: Ovarian stimulation is an essential part of assisted reproduction treatments. Research on whether the duration of stimulation alters the success in assisted reproduction has not been conclusive. AIM: The purpose of the study was to establish whether the duration of ovarian stimulation alters the success in assisted reproduction treatments. METHODS: All fresh (non-donor) stimulation cycles performed in an academic tertiary referral ART centre over a period of 18 years, between 1st January 1997 and 31st December 2014, were identified...
November 7, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27821708/no-increased-risk-of-major-congenital-anomalies-or-adverse-pregnancy-or-neonatal-outcomes-following-letrozole-use-in-assisted-reproductive-technology
#11
T Tatsumi, S C Jwa, A Kuwahara, M Irahara, T Kubota, H Saito
STUDY QUESTION: Does letrozole use increase the risk of major congenital anomalies and adverse pregnancy and neonatal outcomes in fresh, single-embryo transfer? SUMMARY ANSWER: Letrozole significantly decreases the risk of miscarriage and does not increase the risk of major congenital anomalies or adverse pregnancy or neonatal outcomes compared with natural cycles in patients undergoing ART. WHAT IS KNOWN ALREADY: Letrozole is the most commonly used aromatase inhibitor for mild ovarian stimulation in ART...
November 7, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27807847/aspirin-for-in-vitro-fertilisation
#12
REVIEW
Charalampos S Siristatidis, George Basios, Vasilios Pergialiotis, Paraskevi Vogiatzi
BACKGROUND: Aspirin is used with the aim of optimising the chance of live birth in women undergoing assisted reproductive technology (ART), despite inconsistent evidence of its efficacy and safety (in terms of intraoperative bleeding during oocyte retrieval and risk of miscarriage). The most appropriate time to commence aspirin therapy and the length of treatment required are also still to be determined. This is the second update of the review first published in 2007. OBJECTIVES: To evaluate the effectiveness and safety of aspirin in women undergoing ART...
November 3, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27799629/oxidative-stress-and-polycystic-ovary-syndrome-evaluation-during-ovarian-stimulation-for-icsi
#13
Anderson Sanches de Melo, Jhenifer Kliemchen, Alceu Afonso Jordão Junior, Rui A Ferriani, Paula Andrea Navarro
Oxidative stress (OS) may affect natural fertility and the results of assisted reproduction techniques (ARTs). Subfertility associated with polycystic ovary syndrome (PCOS) may be related to OS. This process may intensify during controlled ovarian stimulation (COS) for ARTs because of increased ovarian metabolic activity and hypoestrogenism with the use of gonadotropin-releasing hormone agonists (GnRHas). The objective of this study was to investigate the presence of systemic OS in non-stimulated cycles and to determine OS markers (malondialdehyde [MDA], advanced oxidation protein products [AOPP], hydroperoxides [FOX], glutathione [GSH], and vitamin E) during COS in non-obese infertile women with and without PCOS who were subjected to ARTs...
October 31, 2016: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/27795706/inositol-treatment-and-art-outcomes-in-women-with-pcos
#14
REVIEW
Deepika Garg, Reshef Tal
Polycystic ovary syndrome (PCOS) affects 5-10% of women in reproductive age and is characterized by oligo/amenorrhea, androgen excess, insulin resistance, and typical polycystic ovarian morphology. It is the most common cause of infertility secondary to ovulatory dysfunction. The underlying etiology is still unknown but is believed to be multifactorial. Insulin-sensitizing compounds such as inositol, a B-complex vitamin, and its stereoisomers (myo-inositol and D-chiro-inositol) have been studied as an effective treatment of PCOS...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27762324/maternal-and-live-birth-outcomes-of-pregnancies-following-assisted-reproductive-technology-a-retrospective-cohort-study
#15
Linling Zhu, Yu Zhang, Yifeng Liu, Runjv Zhang, Yiqing Wu, Yun Huang, Feng Liu, Meigen Li, Saijun Sun, Lanfeng Xing, Yimin Zhu, Yiyi Chen, Li Xu, Liangbi Zhou, Hefeng Huang, Dan Zhang
This study was carried out to explore associations between assisted reproductive technology (ART) and maternal and neonatal outcomes compared with similar outcomes following spontaneously conceived births. We conducted a retrospective cohort study of pregnancies conceived by ART (N = 2641) during 2006-2014 compared to naturally conceived pregnancies (N = 5282) after matching for maternal age and birth year. Pregnancy complications, perinatal complications and neonatal outcomes of enrolled subjects were investigated and analysed by multivariate logistic regression...
October 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27752285/molecular-cytogenetic-analysis-of-early-spontaneous-abortions-conceived-from-varying-assisted-reproductive-technology-procedures
#16
Tonghua Wu, Biao Yin, Yuanchang Zhu, Guangui Li, Lijun Ye, Chunmei Chen, Yong Zeng, Desheng Liang
BACKGROUND: Spontaneous abortion (SA) is the most common complication of pregnancy, and chromosome aberrations are the principal cause of the first trimester abortuses in natural conception (NC) The increasing use of assisted reproductive technology (ART) has raised concern about chromosome abnormalities in ART-initiated pregnancies. Up to date, the literature on the risk of aneuploidy in failed pregnancies among various ART factors remain limited and inconclusive. This study aimed to explore the genetic etiology of pregnancy loss conceived from varying ART procedures...
2016: Molecular Cytogenetics
https://www.readbyqxmd.com/read/27741507/effect-of-parental-physiological-conditions-and-assisted-reproductive-technologies-on-the-pregnancy-and-birth-outcomes-in-infertile-patients
#17
Xinqi Zhong, Jianqiao Liu, Qiliang Cui, Shaozhen Liang, Yuanqing Lin, Haiying Liu, Qiyi Zeng
Assisted reproductive technologies (ART) are widely used to treat infertility. Emerging evidence suggested that ART was associated with perinatal or neonatal problems, however, little is known about the ART related risk factors. Here using 21136 ART cases, we determined the impacts of parental physiological conditions in the ART mediated pregnancy outcomes. In addition, we further evaluated the effects of three different ART methods (frozen-thawed embryo transfer [FET], in vitro fertilization [IVF] and intracytoplasmic sperm injection [ICSI]) in the pregnancy and birth outcomes in ART mediated pregnancy...
October 10, 2016: Oncotarget
https://www.readbyqxmd.com/read/27738114/use-of-icsi-in-ivf-cycles-in-women-with-tubal-ligation-does-not-improve-pregnancy-or-live-birth-rates
#18
F W Grimstad, Ajay K Nangia, B Luke, J E Stern, W Mak
STUDY QUESTION: Does ICSI improve outcomes in ART cycles without male factor, specifically in couples with a history of tubal ligation as their infertility diagnosis? SUMMARY ANSWER: The use of ICSI showed no significant improvement in fertilization rate and resulted in lower pregnancy and live birth (LB) rates for women with the diagnosis of tubal ligation and no male factor. WHAT IS KNOWN ALREADY: Prior studies have suggested that ICSI use does not improve fertilization, pregnancy or LB rates in couples with non-male factor infertility...
October 13, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27695610/assisted-reproductive-technology-in-iran-the-first-national-report-on-centers-2011
#19
Mehrandokht Abedini, Azadeh Ghaheri, Reza Omani Samani
BACKGROUND: Due to the worldwide increase in infertility, it is both necessary and important to have assisted reproductive technology (ART) registries. In Iran, donation and surrogacy programs are approved by decrees from religious scholars. ART has been used since 1984 in Iran and the first Iranian infant conceived by gamete intra-fallopian transfer (GIFT) was born in 1989. This report, however, is the first national report on Iranian ART centers. MATERIALS AND METHODS: This cross-sectional study, conducted under the supervision of the Iranian Ministry of Health, presented a summary of the numbers and percentages of centers that provided infertility services in Iran, as well as the status of ART in Iran during 2011...
October 2016: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/27676719/outcomes-of-cryopreserved-sperm-in-case-of-spinal-cord-injury-in-lyon-france
#20
Perrine Séguin, Kathleen Charvier, Frédérique Courtois, Corinne Del Aguila, Bruno Fernandez, Gilles Rode, Jacqueline Lornage, Alain Ruffion, Sandrine Giscard d'Estaing
OBJECTIVE: Sperm cryopreservation can be offered to men with spinal cord injury, as only 10% of spinal cord injured men (SCI) can have a child without assistive reproductive technologies (ART). Very few studies are dedicated to the outcomes of these cryopreservations. Our study aims to analyze the outcomes of these cryopreservation, namely their use or not for an ART, and to evaluate the success rate in case of ART. MATERIAL/PATIENTS AND METHODS: In May 2015, we retrospectively identified all people with stable spinal cord injury sent to the CECOS (Centre d'études de la conservation des œufs et du sperme: Egg, Sperm Embryo banking) by the department of neuroperineology based in the hospital Henry Gabrielle, for the first time between 1st January 2009 and 31st December 2013, to undergo a sperm cryopreservation of spermatozoa...
September 2016: Annals of Physical and Rehabilitation Medicine
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