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https://www.readbyqxmd.com/read/28449168/mri-sequences-in-head-neck-radiology-state-of-the-art
#1
Gerlig Widmann, Benjamin Henninger, Christian Kremser, Werner Jaschke
Background Magnetic resonance imaging (MRI) has become an essential imaging modality for the evaluation of head & neck pathologies. However, the diagnostic power of MRI is strongly related to the appropriate selection and interpretation of imaging protocols and sequences. The aim of this article is to review state-of-the-art sequences for the clinical routine in head & neck MRI and to describe the evidence for which medical question these sequences and techniques are useful. Method Literature review of state-of-the-art sequences in head & neck MRI...
May 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28432404/pediatric-neuro-mri-tricks-to-minimize-sedation
#2
REVIEW
Matthew J Barkovich, Duan Xu, Rahul S Desikan, Cassandra Williams, A James Barkovich
Magnetic resonance imaging (MRI) is the workhorse modality in pediatric neuroimaging because it provides excellent soft-tissue contrast without ionizing radiation. Until recently, studies were uninterpretable without sedation; however, given development of shorter sequences, sequences that correct for motion, and studies showing the potentially deleterious effects of sedation on immature laboratory animals, it is prudent to minimize sedation when possible. This manuscript provides basic guidelines for performing pediatric neuro MRI without sedation by both modifying technical factors to reduce scan time and noise, and using a multi-disciplinary team to coordinate imaging with the patient's biorhythms...
April 22, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28424553/the-world-of-targeted-therapies-in-kidney-cancers-pitfalls-tips-and-tricks
#3
Alexis Vallard, Jane-Chloé Trone, Julien Langrand-Escure, Sophie Espenel, Jean-Baptiste Guy, Chloé Rancoule, Yaoxiong Xia, Anis El Meddeb Hamrouni, Majed Ben Mrad, Nicolas Magné
In the past few years, metastatic renal cell carcinoma prognosis was improved by the development of molecular targeted therapies (TTs). At the metastatic stage, the tolerance to treatment is a major concern, not only because of the challenge of the efficacy/toxicity ratio improvement but also because of the importance of an optimal adherence to oral treatments. The present case series relates the issues of dealing with uncommon and sometimes never described side effects of sunitinib and sorafenib. The first case report deals with grade 3 vomiting during hemodialysis with concurrent administration of sunitinib...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28422392/hepatic-artery-reconstruction-in-living-donor-liver-transplantation-using-surgical-loupes-achieving-low-rate-of-hepatic-arterial-thrombosis-in-consecutive-741-recipients-tips-and-tricks-to-overcome-the-poor-hepatic-arterial-flow
#4
Ping-Chun Li, Ashok Thorat, Long-Bin Jeng, Horng-Ren Yang, Ming-Li Li, Chun-Chieh Yeh, Te-Hung Chen, Shih-Chao Hsu, Kin-Shing Poon
BACKGROUND: The reconstruction of hepatic artery (HA) is most complex step in living donor liver transplantation (LDLT) due to smaller diameter of the artery and increased risk of HA related complications. Due to smaller diameter of the HA, many centres use microsurgical technique with interrupted sutures for arterial anastomosis. Aim of our study was to retrospectively investigate the outcomes after HA reconstruction performed under magnifying loupes using "parachute technique". MATERIALS AND METHODS: From August 2002 to 31(st) August 2016, LDLT was performed in 766 recipients...
April 19, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28415329/kardar-parisi-zhang-equation-with-short-range-correlated-noise-emergent-symmetries-and-nonuniversal-observables
#5
Steven Mathey, Elisabeth Agoritsas, Thomas Kloss, Vivien Lecomte, Léonie Canet
We investigate the stationary-state fluctuations of a growing one-dimensional interface described by the Kardar-Parisi-Zhang (KPZ) dynamics with a noise featuring smooth spatial correlations of characteristic range ξ. We employ nonperturbative functional renormalization group methods to resolve the properties of the system at all scales. We show that the physics of the standard (uncorrelated) KPZ equation emerges on large scales independently of ξ. Moreover, the renormalization group flow is followed from the initial condition to the fixed point, that is, from the microscopic dynamics to the large-distance properties...
March 2017: Physical Review. E
https://www.readbyqxmd.com/read/28411713/cosmetic-sclerotherapy
#6
Jennifer J Watson, M Ashraf Mansour
Telangiectasias and spider veins are considered a common cosmetic concern for both women and men. Sclerotherapy is a frequently used, low-risk, and highly successful method to treat these venous problems. This article reviews the pathophysiology and diagnosis of telangiectasias and reticular veins as well as the currently available agents and techniques of sclerotherapy. The possible complications and adverse outcomes of sclerotherapy are described. Standard care and follow-up for patients after the procedure are outlined...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28408853/tumescent-mastectomy-the-current-indications-and-operative-tips-and-tricks
#7
Ashraf Khater, Alaa Mazy, Mona Gad, Ola Taha Abd Eldayem, Mohamed Hegazy
BACKGROUND: Tumescent mastectomy refers to usage of a mixture of lidocaine and epinephrine in a diluting saline solution that makes flaps firm and tense, thus minimizing systemic drugs toxicity and making surgery possible with minimal bleeding. This technique is very useful in elder women and those with American Society of Anesthesiologists; score III and IV. The objective was to establish an alternative safe technique to general anesthesia in some selected mastectomy patients. PATIENTS AND METHODS: Twenty candidate women for total mastectomy and axillary dissection were enrolled and consented to participate...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28405873/erratum-to-robotic-radical-cystectomy-technical-tips-and-tricks
#8
S S Goonewardene, D M Bolton, N Lawrentschuk
No abstract text is available yet for this article.
April 12, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28400786/effector-mimics-and-integrated-decoys-the-never-ending-arms-race-between-rice-and-xanthomonas-oryzae
#9
REVIEW
Paola Zuluaga, Boris Szurek, Ralf Koebnik, Thomas Kroj, Jean-Benoit Morel
Plants are constantly challenged by a wide range of pathogens and have therefore evolved an array of mechanisms to defend against them. In response to these defense systems, pathogens have evolved strategies to avoid recognition and suppress plant defenses (Brown and Tellier, 2011). Three recent reports dealing with the resistance of rice to Xanthomonas oryzae have added a new twist to our understanding of this fascinating co-evolutionary arms race (Ji et al., 2016; Read et al., 2016; Triplett et al., 2016)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28399743/foolhardy-idea
#10
Claire Brown
Saying that newly qualified nurses should prescribe is like saying a person who has just learned to ride a bike should start using a 10-foot ramp to do tricks without a helmet.
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28399656/teaching-old-dyes-new-tricks-biological-probes-built-from-fluoresceins-and-rhodamines
#11
Luke D Lavis
Small-molecule fluorophores, such as fluorescein and rhodamine derivatives, are critical tools in modern biochemical and biological research. The field of chemical dyes is old; colored molecules were first discovered in the 1800s, and the fluorescein and rhodamine scaffolds have been known for over a century. Nevertheless, there has been a renaissance in using these dyes to create tools for biochemistry and biology. The application of modern chemistry, biochemistry, molecular genetics, and optical physics to these old structures enables and drives the development of novel, sophisticated fluorescent dyes...
April 7, 2017: Annual Review of Biochemistry
https://www.readbyqxmd.com/read/28385644/learning-curve-after-fellowship-in-the-first-3-years-the-junior-faculty-perspective-lessons-tips-and-tricks
#12
EDITORIAL
Jordan E Goldhammer
No abstract text is available yet for this article.
February 3, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28381944/tips-tricks-and-technique-for-laparoscopic-colectomy
#13
REVIEW
Alexandra Briggs, Joel Goldberg
In the United States, there are in excess of 300,000 operations for diseases of the colon yearly. Minimally invasive colectomy became a reality early in the 21st century with the advent of laparoscopic colectomy. The goal of minimally invasive colectomy is to improve postoperative pain control, decrease length of hospital stay, decrease recovery time, decrease complications, and thereby decrease the cost of colon resections. There are many facets to laparoscopic colectomy, including completely laparoscopic approach versus hand-assisted approach and the medial versus lateral approach...
April 2017: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/28380338/understanding-card-tricks-in-apoptosomes
#14
Li Wang, Qi Qiao, Hao Wu
While earlier studies of Apaf-1 holo-apoptosome architecture revealed the spectacular heptameric wheel-like structure formed by Apaf-1, the central CARD disk responsible for caspase-9 recruitment remained incompletely resolved. In a recent issue of Structure, Su et al. (2017) describe a crystal structure of the complex between Apaf-1 CARD and caspase-9 CARD. Together with two recent cryo-EM structures, this work brings us closer to a full view of the holo-apoptosome.
April 4, 2017: Structure
https://www.readbyqxmd.com/read/28380126/factors-associated-with-violence-against-female-sex-workers-in-ten-brazilian-cities
#15
Francisca Sueli da Silva Lima, Edgar Merchán-Hamann, Margarita Urdaneta, Giseli Nogueira Damacena, Célia Landmann Szwarcwald
Few studies in Brazil have focused on violence against female sex workers, a theme that has attracted researchers' attention worldwide, especially due to possible associations with HIV. The current study aims to estimate the prevalence of violence against female sex workers according to type and perpetrator and to identify associated factors. A cross-sectional study was conducted with data on 2,523 female sex workers from ten Brazilian cities, and with the respondent-driven sampling (RDS). Prevalence of verbal violence was 59...
March 30, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28371964/tips-and-tricks-to-improve-clinical-and-aesthetic-outcomes-in-latissimus-dorsi-flap-breast-reconstruction
#16
Rosaria Laporta, Michail Sorotos, Benedetto Longo, Fabio Santanelli di Pompeo
Background The aim of this study is to present technical strategies to decrease donor-site complications, to optimize breast shaping, and to achieve symmetry in one-stage procedure in latissimus dorsi (LD) flap reconstruction. Methods Between 2004 and 2014, a retrospective review was performed on LD flap reconstructions. Demographics, reconstructive details, clinical, and aesthetic outcomes were collected and analyzed. Patients were divided in historical control group (HCG) and new strategy group (NSG)...
April 3, 2017: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/28369771/intervention-radiology-for-venous-thrombosis-early-thrombus-removal-using-invasive-methods
#17
REVIEW
Ana I Casanegra, Robert D McBane, Haraldur Bjarnason
The post thrombotic syndrome is one of the most dreaded complications of proximal deep vein thrombosis. This syndrome leads to pain and suffering with leg swelling, recalcitrant ulceration and venous claudication which greatly impairs mobility and quality of life. The prevalence can be high in patients with iliofemoral venous involvement particularly in the setting of a proximal venous stenosis, such as occurs in May Thurner syndrome. Anticoagulation alone does not reduce the likelihood of this outcome. Compression therapy may be effective but garment discomfort limits its implementation...
April 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28368816/multi-target-regression-via-robust-low-rank-learning
#18
Xiantong Zhen, Mengyang Yu, Xiaofei He, Shuo Li
Multi-target regression has recently regained great popularity due to its capability of simultaneously learning multiple relevant regression tasks and its wide applications in data mining, computer vision and medical image analysis, while great challenges arise from jointly handling inter-target correlations and input-output relationships. In this paper, we propose Multilayer Multi-target Regression (MMR) which enables simultaneously modeling intrinsic inter-target correlations and nonlinear input-output relationships in a general framework via robust low-rank learning...
March 28, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28361689/avc-selecting-discriminative-features-on-basis-of-auc-by-maximizing-variable-complementarity
#19
Lei Sun, Jun Wang, Jinmao Wei
BACKGROUND: The Receiver Operator Characteristic (ROC) curve is well-known in evaluating classification performance in biomedical field. Owing to its superiority in dealing with imbalanced and cost-sensitive data, the ROC curve has been exploited as a popular metric to evaluate and find out disease-related genes (features). The existing ROC-based feature selection approaches are simple and effective in evaluating individual features. However, these approaches may fail to find real target feature subset due to their lack of effective means to reduce the redundancy between features, which is essential in machine learning...
March 14, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28353024/teaching-an-old-dog-new-tricks-colchicine-in-cardiovascular-medicine
#20
REVIEW
Kevin Chen, Aldo L Schenone, Nyal Borges, Michael Militello, Venu Menon
Colchicine is one of the oldest known drugs that remains part of the current pharmacopeia. Recent studies have examined the efficacy of colchicine in cardiology with promising results. We conducted a search of electronic databases for studies on colchicine in cardiovascular medicine published through October 2016. As the utilization of colchicine in the management of cardiac conditions grows, it is paramount that internists and cardiologists are familiarized with its benefits and risks. We present a comprehensive review of the role of colchicine in the management of cardiovascular diseases with a strong emphasis on side effects and potential drug interactions...
March 28, 2017: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
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