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Nidhi Rawat, Michael O Pumphrey, Sixin Liu, Xiaofei Zhang, Vijay K Tiwari, Kaori Ando, Harold N Trick, William W Bockus, Eduard Akhunov, James A Anderson, Bikram S Gill
Fusarium head blight (FHB), caused by Fusarium graminearum, is a devastating disease of wheat and barley that leads to reduced yield and mycotoxin contamination of grain, making it unfit for human consumption. FHB is a global problem, with outbreaks in the United States, Canada, Europe, Asia and South America. In the United States alone, total direct and secondary economic losses from 1993 to 2001 owing to FHB were estimated at $7.67 billion. Fhb1 is the most consistently reported quantitative trait locus (QTL) for FHB resistance breeding...
October 24, 2016: Nature Genetics
Eric S Molho, Mark Stacy, Patrick Gillard, David Charles, Charles H Adler, Joseph Jankovic, Marc Schwartz, Mitchell F Brin
BACKGROUND: Cervical dystonia is thought to result in high disease burden, but limited information exists on its impact on employment and work productivity. We utilized data from the Cervical Dystonia Patient Registry for the Observation of OnabotulinumtoxinA Efficacy ( identifier: NCT00836017) to assess the impact of cervical dystonia on employment and work productivity and examine the effect of onabotulinumtoxinA treatments on work productivity. METHODS: Subjects completed a questionnaire on employment status and work productivity at baseline and final visit...
March 2016: Movement Disorders Clinical Practice
Justin P Ingram, Igor E Brodsky, Siddharth Balachandran
Salmonella enterica is a facultative intracellular bacterium that is the leading cause of food borne illnesses in humans. The cytokine IFN-γ has well-established antibacterial properties against Salmonella and other intracellular microbes, for example its capacity to activate macrophages, promote phagocytosis, and destroy phagocytosed microbes by free radical-driven toxification of phagosomes. But IFN-γ induces the expression of hundreds of uncharacterized genes, suggesting that this cytokine deploys additional antimicrobial strategies that await discovery...
October 20, 2016: Cytokine
Tiffany Hughes, Tony Badrick
No abstract text is available yet for this article.
February 2016: Pathology
Michael Talerico, Jaimo Ahn
The objective of this article is to highlight the salient points of preoperative planning, intraoperative considerations for fracture reduction methods, and implant fixation when treating distal diaphyseal or diametaphyseal tibia fractures with an intramedullary nail. Through review of the necessary preoperative considerations, techniques available to hold and maintain a reduction, and lastly how to maximize the selected implant of intramedullary nail, we hope to assist the treating surgeon in simplifying these sometimes complex fractures into manageable injuries that can be treated successfully with an intramedullary implant...
November 2016: Journal of Orthopaedic Trauma
Giovanni Milito, Giorgio Lisi, Elena Aronadio, Michela Campanelli, Dario Venditti, Simona Grande, Michele Grande
BACKGROUNDS: Hemorrhoidectomy is considered the gold standard and the most effective and definitive treatment for grades 3 or 4 haemorrhoids, and Milligan-Morgan's and Ferguson's procedures are the most widely used techniques throughout the world. The aim of the study is to present our surgical technique using LigasureTM vessel sealing, focus on technical aspects and surgical tricks showing our results with a huge number of patients and a long-term follow-up. METHODS: Between June 2001 and June 2014 at the University Hospital of Tor Vergata, Rome, Italy, 1000 patients were selected to underwent LigaSureTM hemorrhoidectomy for III and IV degree haemorrhoids...
October 21, 2016: Minerva Gastroenterologica e Dietologica
James C Blankenship, Wayne A Powell, Dawn R Gray, Peter L Duffy
Interventional cardiology has finally completed, after 26 years of advocacy, a professional hat trick: independent board certification, membership as a unique specialty in the American Medical Association House of Delegates (AMA HOD), and recognition by the Centers for Medicaid and Medicare Services (CMS) as a separate medical specialty. This article points out how these distinctions for interventional cardiology and its professional society, the Society for Cardiovascular Angiography and Interventions (SCAI), have led to clear and definite benefits for interventional cardiologists and their patients...
October 19, 2016: Catheterization and Cardiovascular Interventions
Suparna Bharadwaj, Jaya Wanchoo, Harsh Sapra
No abstract text is available yet for this article.
October 17, 2016: Journal of Neurosurgical Anesthesiology
Katherine C Konvinse, Elizabeth J Phillips, Katie D White, Jason A Trubiano
PURPOSE OF REVIEW: Antimicrobials are a leading cause of severe T cell-mediated adverse drug reactions (ADRs). The purpose of this review is to address the current understanding of antimicrobial cross-reactivity and the ready availability of and evidence for in-vitro, in-vivo, and ex-vivo diagnostics for T cell-mediated ADRs. RECENT FINDINGS: Recent literature has evaluated the efficacy of traditional antibiotic allergy management, including patch testing, skin prick testing, intradermal testing, and oral challenge...
October 7, 2016: Current Opinion in Infectious Diseases
Scott A Norris, H A Jinnah, Alberto J Espay, Christine Klein, Norbert Brüggemann, Richard L Barbano, Irene Andonia C Malaty, Ramon L Rodriguez, Marie Vidailhet, Emmanuel Roze, Stephen G Reich, Brian D Berman, Mark S LeDoux, Sarah Pirio Richardson, Pinky Agarwal, Zoltan Mari, William G Ondo, Ludy C Shih, Susan H Fox, Alfredo Berardelli, Claudia M Testa, Florence Ching-Fen Cheng, Daniel Truong, Fatta B Nahab, Tao Xie, Mark Hallett, Ami R Rosen, Laura J Wright, Joel S Perlmutter
BACKGROUND: Clinical characteristics of isolated idiopathic cervical dystonia such as onset site and spread to and from additional body regions have been addressed in single-site studies with limited data and incomplete or variable dissociation of focal and segmental subtypes. The objectives of this study were to characterize the clinical characteristics and demographics of isolated idiopathic cervical dystonia in the largest standardized multicenter cohort. METHODS: The Dystonia Coalition, through a consortium of 37 recruiting sites in North America, Europe, and Australia, recruited 1477 participants with focal (60...
October 18, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
Simon A Moss, Melanie Irons, Martin Boland
BACKGROUND AND AIMS: Lecturers often present entertaining videos, or organize a variety of amusing demonstrations, to foster student engagement or to encourage critical analysis. Magic tricks, in particular, have been shown to activate neural circuits that underpin motivation or problem-solving and, therefore, could be beneficial during lectures. Nevertheless, we hypothesize that, unless the method that underpins these tricks is revealed, students may ruminate over possible explanations, distracting attention from the lecture material...
October 18, 2016: British Journal of Educational Psychology
Simon J Labrie, Sylvain Moineau
Bacterial genomic islands contain hidden treasures. In this issue of Cell Host & Microbe, Depardieu et al. (2016) found, in one of those islands, an altruistic anti-phage system that is triggered by a phage component and induces a phosphorylation cascade leading to protection of the bacterial population.
October 12, 2016: Cell Host & Microbe
Xin-Xing Zhan, Xin Zhang, Si-Min Dai, Shu-Hui Li, Xu-Zhai Lu, Lin-Long Deng, Su-Yuan Xie, Rong-Bin Huang, Lan-Sun Zheng
Despite being widely used as electron acceptor in polymer solar cells, commercially available PC71BM (phenyl-C71-butyric acid methyl ester) usually has a "random" composition of mixed regioisomers or stereoisomers. Here the PC71BM has been isolated into three typical isomers, α-, β1- and β2-PC71BM, for establishing the isomer-dependent photovoltaic performance on change of ternary composition of α-, β1- and β2-PC71BM. Mixing the isomers in a ratio of α:β1:β2=8:1:1 resulted in the best power conversion efficiency (PCE) of 7...
October 13, 2016: Chemistry: a European Journal
Gaetano Di Rienzo, Corrado Surrente, Camillo Lopez, Giovanna Imbriglio, Gaetano Greco, Anna Lucia Urgese, Luigi Andriolo
In 2012, open procedures represented 63% of the total number of lobectomies performed in our unit; in 2015, video-assisted thoracoscopic surgery (VATS) lobectomy numbers increased up to 66% of the total number of lobectomies performed. When carrying out the procedures, we followed the guidelines presented by the International VATS Lobectomy Consensus Group regarding indications, contraindications, preoperative investigations and conversions. In view of 280 VATS major lung resections from May 2012 to May 2016, we describe some tips and tricks that can be useful in this surgical technique, from general principles to single operative procedures...
October 13, 2016: Future Oncology
André Klostermann, Philip Küng
PURPOSE: This study aimed to further the knowledge on gaze behavior in locomotion by studying gaze strategies in skateboard jumps of different difficulty that had to be performed either with or without an obstacle. METHOD: Nine experienced skateboarders performed "Ollie" and "Kickflip" jumps either over an obstacle or over a plane surface. The stable gaze at 5 different areas of interest was calculated regarding its relative duration as well as its temporal order...
October 12, 2016: Research Quarterly for Exercise and Sport
Abdelrahman A Nimeri, Ahmed Maasher, Talat Al Shaban, Elnazeer Salim, Maha Ibrahim
BACKGROUND: Conversion of laparoscopic adjustable gastric banding (LAGB) to other operations is commonly done for significant weight recidivism and complications. METHODS: This is a consecutive series of LAGB converted to RYGB done at the Bariatric and Metabolic Institute (BMI) Abu Dhabi from 2009 to 2013 for weight recidivism. Our preferred approach is to convert LAGB to LRYGB in one stage. All patients undergo upper endoscopy (EGD) and upper gastrointestinal series and are started on clears liquids 2 h after surgery without performing UGI studies...
October 12, 2016: Obesity Surgery
Luigi Mearini, Elisabetta Nunzi, Manuel Di Biase, Elisa Silvi, Ilaria Sabatini, Massimo Porena
OBJECTIVES: The current report describes the feasibility of robotic retroperitoneal lymph node dissection (RRPLND), including some technical tricks for port placement for both right- and left-sided surgery. METHODS: Patients with advanced stage retroperitoneal disease underwent RRPLND using the 4-arm da Vinci Si Surgical System (Intuitive Surgical, Inc.). In both cases, the field of dissection was an ipsilateral template for lymph node dissection. RESULTS: RRPLND in such configuration was safe and effective in both cases...
October 11, 2016: Urologia Internationalis
Qiuling Hou, Meng Lv, Ling Zhen, Ling Jing
Although support vector machine (SVM) has become a powerful tool for pattern classification and regression, a major disadvantage is it fails to exploit the underlying correlation between any pair of data points as much as possible. Inspired by the modified pairwise constraints trick, in this paper, we propose a novel classifier termed as support vector machine with hypergraph-based pairwise constraints to improve the performance of the classical SVM by introducing a new regularization term with hypergraph-based pairwise constraints (HPC)...
2016: SpringerPlus
Sunit K Singh
HIV-Tat protein displays an array of functions, essential for successful HIV replication. The structural flexibility of Tat protein has been regarded as one of the unique features responsible for sustaining diverse functions, ranging from cell membrane-crossing ability to strong affinity for RNA binding. RNA binding ability and presence of multiple interacting domains in the same protein is very important property of HIV-Tat protein. Tat protein has shown great ability to influence cellular and viral gene expression...
October 6, 2016: Current HIV Research
Eugene J Mahon
No abstract text is available yet for this article.
October 2016: Psychoanalytic Quarterly
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