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https://www.readbyqxmd.com/read/29045957/-clinical-characteristics-of-neonatal-fungal-sepsis-in-neonatal-intensive-care-unit
#1
X Zhang, X F Ru, Y Wang, X Li, T Sang, Q Feng
OBJECTIVE: To study the characteristics of neonatal fungal sepsis and the difference between bacterial sepsis and fungal sepsis. To improve the understanding of neonatal fungal sepsis. METHODS: Clinical data of neonatal fungal sepsis in neonatal intensive care unit (NICU) were collected from 2011 to 2016 in Peking University first Hospital. The clinical characteristics were analyzed retrospectively. The difference between neonatal fungal sepsis and bacterial sepsis was also analyzed...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045765/oral-anti-diabetic-agents-for-women-with-established-diabetes-impaired-glucose-tolerance-or-previous-gestational-diabetes-planning-pregnancy-or-pregnant-women-with-pre-existing-diabetes
#2
REVIEW
Joanna Tieu, Suzette Coat, William Hague, Philippa Middleton, Emily Shepherd
BACKGROUND: While most guidance recommends the use of insulin in women whose pregnancies are affected by pre-existing diabetes, oral anti-diabetic agents may be more acceptable to women. The effects of these oral anti-diabetic agents on maternal and infant health outcomes need to be established in pregnant women with pre-existing diabetes or impaired glucose tolerance, as well as in women with previous gestational diabetes mellitus preconceptionally or during a subsequent pregnancy. OBJECTIVES: To investigate the effects of oral anti-diabetic agents in women with established diabetes, impaired glucose tolerance or previous gestational diabetes who are planning a pregnancy, or pregnant women with pre-existing diabetes, on maternal and infant health...
October 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29045653/a-quality-improvement-project-to-reduce-hypothermia-in-preterm-infants-on-admission-to-the-neonatal-intensive-care-unit
#3
Wai Yan Yip, Bin Huey Quek, Mary Choi Wan Fong, Thilagamangai, Sally Siew Gim Ong, Bee Leong Lim, Bo Chu Lo, Pratibha Agarwal
Objective: To study effectiveness of quality improvement interventions in reducing hypothermia in preterm infants on admission to neonatal intensive care unit. Design: Quality improvement methodologies including multidisciplinary planning and implementation of evidence-based interventions. Data during and post-implementation were collected. Setting and participants: In total, 84 preterm infants with birth weights ≤ 1500 g delivered during implementation period (October 2008-April 2009) were compared with 168 historical controls and 947 infants in the subsequent 4 years...
October 17, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29044351/surgical-management-of-necrotizing-enterocolitis-in-an-incredibly-low-birth-weight-infant-and-review-of-the-literature
#4
A Zangari, C Noviello, S Nobili, G Cobellis, C Gulia, R Piergentili, S Gigli, V Carnielli
Survival of preterm infants have dramatically improved over the last decades. Nonetheless, infants born preterm remain vulnerable to many complications, including necrotizing enterocolitis (NEC). The severity of the disease and the mortality rate are directly correlated with decreasing gestational age and birth weight. Despite surgical treatment mortality rate remains very high in extremely premature infants, especially in newborns at the lowest limit of viability. Survival of infants of birth weight (BW) below 750 g has been increasingly reported in recent years, however the overall mortality in extremely low "BW" infants (ELBW) requiring surgery for NEC has not decreased over the past years...
September 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29042061/analysis-of-selected-aspects-of-inflammasome-function-in-the-monocytes-from-neonates-born-extremely-and-very-prematurely
#5
Magdalena Zasada, Marzena Lenart, Magdalena Rutkowska-Zapała, Małgorzata Stec, Nina Mól, Ola Czyz, Maciej Siedlar, Przemko Kwinta
BACKGROUND: Inflammasomes regulate activation of caspase-1, which cleaves and activates interleukin (IL)-1β and IL-18, the cytokines that trigger pro-inflammatory and antimicrobial responses. There is very little known about inflammasome function in the subsets of monocytes (MO) isolated from preterm neonates born extremely and very prematurely. METHODS: A group of 76 very low birth weight patients without early-onset sepsis was divided into extremely preterm (<28 gestational week) or very preterm (28-32 gestational week) neonates...
October 5, 2017: Immunobiology
https://www.readbyqxmd.com/read/29041034/inhaled-versus-systemic-corticosteroids-for-preventing-bronchopulmonary-dysplasia-in-ventilated-very-low-birth-weight-preterm-neonates
#6
REVIEW
Sachin S Shah, Arne Ohlsson, Henry L Halliday, Vibhuti S Shah
BACKGROUND: Bronchopulmonary dysplasia (BPD) remains an important cause of mortality and morbidity in preterm infants and inflammation plays a significant role in its pathogenesis. The use of inhaled corticosteroids may modulate the inflammatory process without concomitant high systemic steroid concentrations and less risk of adverse effects. This is an update of a review published in 2012 (Shah 2012). We recently updated the related review on "Inhaled versus systemic corticosteroids for treating bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates"...
October 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29040820/systematic-review-of-the-effect-of-enteral-feeding-on-gut-microbiota-in-preterm-infants
#7
Wanli Xu, Michelle Judge, Kendra Maas, Naveed Hussain, Jacqueline M McGrath, Wendy A Henderson, Xiaomei Cong
OBJECTIVE: To examine the effect of feeding type on microbial patterns among preterm infants and to identify feeding factors that promote the colonization of beneficial bacteria. DATA SOURCES: PubMed, Cochrane Database of Systematic Reviews, Scopus, and the Cummulative Index of Nursing and Allied Health Literature were thoroughly searched for articles published between January 2000 and January 2017, using the keywords gut microbiome, gut microbiota, enteral microbiome, enteral microbiota, premature infant, preterm infant, extremely low birth weight infant, ELBW infant, very low birth weight infant, feeding, breast milk, breastfeeding, formula, prebiotic, probiotic, and long chain polyunsaturated fatty acid...
October 14, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29040312/end-tidal-carbon-dioxide-measurement-in-preterm-infants-with-low-birth-weight
#8
Hsin-Ju Lin, Ching-Tzu Huang, Hsiu-Feng Hsiao, Ming-Chou Chiang, Mei-Jy Jeng
OBJECTIVE: There are conflicting data regarding the use of end-tidal carbon dioxide (PetCO2) measurement in preterm infants. The aim of this study was to evaluate the effects of different dead space to tidal volume ratios (VD/VT) on the correlation between PetCO2 and arterial carbon dioxide pressure (PaCO2) in ventilated preterm infants with respiratory distress syndrome (RDS). METHODS: We enrolled ventilated preterm infants (with assist control mode or synchronous intermittent mandatory mode) with RDS who were treated with surfactant in this prospective study...
2017: PloS One
https://www.readbyqxmd.com/read/29039438/chondroitin-sulfate-proteoglycans-inhibit-the-migration-and-differentiation-of-oligodendrocyte-precursor-cells-and-its-counteractive-interaction-with-laminin
#9
Yi Sun, Yingping Deng, Mili Xiao, Lan Hu, Zhihua Li, Chao Chen
Cerebral white matter injury (WMI) is a recognized problem in premature infants, particularly in those with very low birth weights. Although the survival rate of premature infants has notably increased due to the advancement of modern medical treatments, their likelihood of developmental disability is higher than infants with an average birth weight. It has been previously reported that oligodendrocyte precursor cells (OPCs) are selectively vulnerable to WMI in premature infants. Following brain injury, glial scars may develop within the white matter...
September 27, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29038711/study-of-the-c677t-and-1298ac-polymorphic-genotypes-of-mthfr-gene-in-autism-spectrum-disorder
#10
Farida El-Baz, Mohammed Abd El-Aal, Tarek Moustafa Kamal, Abdelrahim Abdrabou Sadek, Amr Ahmed Othman
BACKGROUND: Autism is currently known as "a behaviorally defined syndrome" manifested as impairment in social communication, repetitive routines and restricted interests. There is an increased risk of ASDs associated with common mutations affecting the folate/methylation cycle. AIM: The aim of this study was to identify C677T and 1298AC polymorphic genotypes of MTHFR gene among a sample of Egyptian children with autism and to make a phenotype-genotype correlation for the autistic patients...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29037267/tracking-of-infant-and-young-child-feeding-practices-among-9-to-24-month-old-children-in-nepal-the-mal-ed-birth-cohort-study
#11
Marianne S Morseth, Liv Elin Torheim, Mekdes K Gebremariam, Ram K Chandyo, Manjeswori Ulak, Sanjaya K Shrestha, Binob Shrestha, Sigrun Henjum
OBJECTIVE: The present study aimed to assess infant and young child feeding (IYCF) practices and the tracking of dietary diversity score (DDS), intakes of Fe- and vitamin A-rich foods and meal frequency in a peri-urban area in Nepal. Furthermore, to explore whether sociodemographic factors were associated with tracking patterns of these IYCF practices. DESIGN: Longitudinal study. Monthly food intake was measured by 24 h recall. Four time slots were used (9-12, 13-16, 17-20 and 21-24 months)...
October 17, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29037176/the-association-between-high-birth-weight-and-the-risks-of-childhood-cns-tumors-and-leukemia-an-analysis-of-a-us-case-control-study-in-an-epidemiological-database
#12
Long Thanh Tran, Hang Thi Minh Lai, Chihaya Koriyama, Futoshi Uwatoko, Suminori Akiba
BACKGROUND: High birth weight (BW), 4000 g or larger, is an established risk factor for childhood leukemia. However, its association with central nervous system (CNS) tumor risk is yet unclear. The present study examined it, analyzing data obtained from a case-control study conducted among three states from the US. The association with childhood leukemia risk was also further examined. METHODS: In this study, a data set provided by the Comprehensive Epidemiologic Data Resource was analyzed with an official permission...
October 16, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29037175/a-ten-year-study-of-midwife-led-care-at-an-austrian-tertiary-care-center-a-retrospective-analysis-with-special-consideration-of-perineal-trauma
#13
Barbara Bodner-Adler, Oliver Kimberger, Julia Griebaum, Peter Husslein, Klaus Bodner
BACKGROUND: In contrast to other countries, Austria rarely offers alternative models to medical led-care. In an attempt to improve the facilities, a midwife-led care service was incorporated within the Department of Obstetrics and Fetomaternal Medicine. The aim of the present study was to analyze the maternal and neonatal outcomes of this approach. METHODS: Over a 10-years period, a total of 2123 low-risk women receiving midwife-led care were studied. Among these women, 148 required obstetric referral...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29037105/the-role-of-female-obesity-on-in-vitro-fertilization-outcomes
#14
Miro Kasum, Slavko Orešković, Ermin Čehić, Albert Lila, Emina Ejubović, Dragan Soldo
The aim of this review is to analyze the role of obesity on fertility outcome in women undergoing in vitro fertilization (IVF) with respect to clinical or live birth rates and pregnancy loss rates. Despite findings from several earlier and newer studies that obesity does not adversely affect pregnancy outcome in women attempting conception, numerous reports from mostly recent studies suggest that obesity undoubtedly impairs IVF outcomes. Obesity impairs ovarian responsiveness to gonadotrophin stimulation, requiring higher doses of medication, increased risk of cycle cancelation, pre-term delivery, low birth weight or miscarriage, and decreases implantation, clinical pregnancy or live birth rates compared to women of normal weight...
October 16, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29036471/immunization-completion-in-infants-born-at-low-birth-weight
#15
Matt Nestander, Jay Dintaman, Apryl Susi, Gregory Gorman, Elizabeth Hisle-Gorman
Background: Low birth weight (LBW) has been associated with underimmunization. We sought to understand the effect of LBW on immunization completion after controlling for previously hypothesized mediators, including prematurity, neonatal illness, well-child care, non-well-child visits, and provider consistency. Methods: We formed a retrospective cohort of infants born between 2008 and 2011 with ≥2 years of military healthcare follow-up. International Classification of Diseases, Ninth Revision codes were used to identify LBW, preterm birth, neonatal illnesses, well-child visits, non-well-child visits, provider consistency, and parental rank in the inpatient and outpatient records...
September 23, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29035425/inhaled-versus-systemic-corticosteroids-for-the-treatment-of-bronchopulmonary-dysplasia-in-ventilated-very-low-birth-weight-preterm-infants
#16
REVIEW
Sachin S Shah, Arne Ohlsson, Henry L Halliday, Vibhuti S Shah
BACKGROUND: This is an update of a review published in 2012. A related review "Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates" has been updated as well. Bronchopulmonary dysplasia (BPD) is a serious and common problem among very low birth weight infants, despite the use of antenatal steroids and postnatal surfactant therapy to decrease the incidence and severity of respiratory distress syndrome. Due to their anti-inflammatory properties, corticosteroids have been widely used to treat or prevent BPD...
October 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29034551/early-breastfeeding-practices-descriptive-analysis-of-recent-demographic-and-health-surveys
#17
Laura Oakley, Lenka Benova, David Macleod, Caroline A Lynch, Oona M R Campbell
The aim of this study was to describe early breastfeeding practices (initiation within 1 hr of birth, no prelacteal feeding, and a combination of both-"optimal" early breastfeeding) according to childbirth location in low- and middle-income countries. Using data from the most recent Demographic and Health Survey (2000-2013) for 57 countries, we extracted information on the most recent birth for women aged 15-49 with a live birth in the preceding 24 months. Childbirth setting was self-reported by location (home or facility) and subtype (home delivery with or without a skilled birth attendant; public or private facility)...
October 16, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29033411/relationship-between-the-clinical-course-of-ulcerative-colitis-during-pregnancy-and-the-outcomes-of-pregnancy-a-retrospective-evaluation
#18
Ayumi Ito, Bunei Iizuka, Teppei Omori, Shinichi Nakamura, Katsutoshi Tokushige
Background Little information is available on the relationship between the clinical course of ulcerative colitis (UC) and the outcomes of pregnancy and delivery in pregnant Japanese women. The aim of this retrospective study was to determine the factors that influence pregnancy and childbirth in middle-aged UC patients. Methods We studied 53 pregnancies in 45 pregnant women with UC who delivered at our department. They included 41 pregnancies that started while in UC remission and 12 pregnancies that started in the UC active phase...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29032790/formative-qualitative-research-to-develop-community-based-interventions-addressing-low-birth-weight-in-the-plains-of-nepal
#19
Joanna Morrison, Sophiya Dulal, Helen Harris-Fry, Machhindra Basnet, Neha Sharma, Bhim Shrestha, Dharma Manandhar, Anthony Costello, David Osrin, Naomi Saville
OBJECTIVE: To explore the factors affecting intra-household food allocation practices to inform the development of interventions to prevent low birth weight in rural plains of Nepal. DESIGN: Qualitative methodology using purposive sampling to explore the barriers and facilitating factors to improved maternal nutrition. SETTING: Rural Dhanusha District, Nepal. SUBJECTS: We purposively sampled twenty-five young daughters-in-law from marginalised groups living in extended families and conducted semi-structured interviews with them...
October 16, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29032242/combination-of-vitamin-b12-active-forms-improved-fetal-growth-in-wistar-rats-through-up-regulation-of-placental-mir-16-and-mir-21-levels
#20
Tejas Shah, Sanjay Mishra, Amol More, Suhas Otiv, Kishori Apte, Kalpana Joshi
Aim Epidemiological studies have indicated importance of folate and vitamin (B12) during pregnancy. Also available evidence on efficacy of B12 forms viz. Cyanocobalamin (Cbl), Methylcobalamin (MeCbl), Adenosylcobalamin (AdCbl) and Hydroxycobalamin (HCbl) in preventing or treating cobalamin deficiency is limited. The present study examines the effect of various B12 forms in combination with folate during pregnancy and their effect on gestational outcomes. MAIN METHOD: In the present study, we examined the effect of various vitamin B12 forms in presence of recommended folate (RFol: 400μg/day) and high folate (HFol: 5mg/day) on gestational outcomes in female Wistar rats...
October 12, 2017: Life Sciences
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